Compounds > 3,4-dimethylbenzaldehyde
Page last updated: 2024-12-06

3,4-dimethylbenzaldehyde

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

3,4-dimethylbenzaldehyde is an organic compound with the formula CH3C6H3(CH3)CHO. It is a colorless liquid with a pungent odor. It is used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, dyes, and fragrances. 3,4-dimethylbenzaldehyde is also used as a flavoring agent in foods and beverages. The compound is synthesized by the Friedel-Crafts acylation of toluene with acetyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. The resulting product is then oxidized to the corresponding aldehyde using a suitable oxidizing agent, such as potassium permanganate. 3,4-dimethylbenzaldehyde is a known irritant and can cause skin and eye irritation. It is also a potential allergen. The compound is studied for its potential applications in various fields, such as organic synthesis, medicine, and cosmetics. Its reactivity and versatility make it a valuable starting material for the development of new and useful compounds.'

Cross-References

ID SourceID
PubMed CID22278
CHEMBL ID3187739
CHEBI ID167406
SCHEMBL ID98097
MeSH IDM0453407

Synonyms (41)

Synonym
EN300-22064
CHEBI:167406
benzaldehyde, 3,4-dimethyl-
3,4-dimethylbenzaldehyde
3,4-dimethylbenzaldehyde, 98%
o-xylene-4-carboxaldehyde
5973-71-7
D3334
inchi=1/c9h10o/c1-7-3-4-9(6-10)5-8(7)2/h3-6h,1-2h3
poqjhlbmlvthau-uhfffaoysa-
A832442
3,4-dimethyl-benzaldehyde
3 pound not4-dimethylbenzaldehyde
dtxcid0021626
tox21_301638
NCGC00255646-01
cas-5973-71-7
dtxsid2041626 ,
unii-16g1j12arb
ec 227-770-2
16g1j12arb ,
einecs 227-770-2
AKOS009075842
FT-0614367
PS-4693
4-formyl-o-xylene
SCHEMBL98097
3,4-dimethyl benzaldehyde
3,4 dimethyl benzaldehyde
3,4-di-methylbenzaldehyde
SY004808
mfcd00016612
Q-200344
CHEMBL3187739
AC-3245
AC-15539
BCP24427
STL185667
Q27251808
CS-W013376
Z147641440
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
carbonyl compoundAny compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.61 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index34.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.		2.0110alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
hydrogen
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.		2.0310elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
pseudocumene
1,2,4-trimethylbenzene : A trimethylbenzene carrying methyl groups at positions 1, 2 and 4.		2.4220trimethylbenzeneneurotoxin
diethylhexyl phthalate
Diethylhexyl Phthalate: An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.. bis(2-ethylhexyl) phthalate : A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.		2.0110diester;
phthalate ester		androstane receptor agonist;
apoptosis inhibitor;
plasticiser
ConditionIndicatedRelationship StrengthStudiesTrials
Germinoblastoma
[description not available]		02.1710
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue.		02.1710
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.0110