tinidazole has been researched along with Sensitivity and Specificity in 12 studies
Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fifty patients with active or scarred duodenal ulcer were randomized to lansoprazole or omeprazole for 1 to 4 weeks, with clarithromycin 250 mg twice a day and tinidazole 500 mg twice a day for the first week." | 9.09 | Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. ( Fanti, L; Guslandi, M; Ieri, R; Mezzi, G; Passaretti, S; Testoni, PA, 2001) |
| " Fifty patients with active or scarred duodenal ulcer were randomized to lansoprazole or omeprazole for 1 to 4 weeks, with clarithromycin 250 mg twice a day and tinidazole 500 mg twice a day for the first week." | 5.09 | Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. ( Fanti, L; Guslandi, M; Ieri, R; Mezzi, G; Passaretti, S; Testoni, PA, 2001) |
| " Concentrations of brazilin in plasma were determined by HPLC method at different time points and all pharmacokinetic parameters were estimated by non-compartmental analysis with WinNonLin 6." | 1.40 | A simple high-performance liquid chromatographic method for the determination of brazilin and its application to a pharmacokinetic study in rats. ( Ai-dong, W; Fang, D; Jinyi, Z; Yan, L; Yan-yan, J; Ying, S; Yuan, S, 2014) |
| " The validated method was applied to assay real plasma samples used for pharmacokinetic studies and therapeutic drug monitoring of the selected drugs." | 1.39 | Simultaneous quantification of linezolid, tinidazole, norfloxacin, moxifloxacin, levofloxacin, and gatifloxacin in human plasma for therapeutic drug monitoring and pharmacokinetic studies in human volunteers. ( Helmy, SA, 2013) |
| " The validated method was applied for the analysis of in vivo pharmacokinetic (PK) study samples after intravenous administration of MTZ to a rat." | 1.37 | Dried blood spot assay for estimation of metronidazole concentrations in rats and its application in single animal drug pharmacokinetic study. ( Donnelly, RF; Garland, MJ; Kole, PL; Majithia, R; McElnay, J; Migalska, K; Singh, TR, 2011) |
| "Secnidazole was then separated by HPLC on a Diamond C(18) column and quantified by ultraviolet detection at 319 nm." | 1.34 | Determination of secnidazole in human plasma by high-performance liquid chromatography with UV detection and its application to the bioequivalence studies. ( Gu, Y; Li, X; Ren, H; Sun, J; Wang, G; Xie, H; Yan, B; Zheng, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helmy, SA | 1 |
| Yan-yan, J | 1 |
| Yan, L | 1 |
| Ying, S | 1 |
| Jinyi, Z | 1 |
| Fang, D | 1 |
| Yuan, S | 1 |
| Ai-dong, W | 1 |
| Ye, G | 1 |
| Cai, X | 1 |
| Wang, B | 1 |
| Zhou, Z | 1 |
| Yu, X | 1 |
| Wang, W | 1 |
| Zhang, J | 1 |
| Wang, Y | 2 |
| Dong, J | 1 |
| Jiang, Y | 1 |
| Kole, PL | 1 |
| Majithia, R | 1 |
| Singh, TR | 1 |
| Garland, MJ | 1 |
| Migalska, K | 1 |
| Donnelly, RF | 1 |
| McElnay, J | 1 |
| Zhang, P | 1 |
| Jiang, N | 1 |
| Gong, X | 1 |
| Meng, L | 1 |
| Wang, D | 1 |
| Ou, N | 1 |
| Zhang, H | 1 |
| Mohammad, MA | 1 |
| Zawilla, NH | 1 |
| El-Anwar, FM | 1 |
| El-Moghazy Aly, SM | 1 |
| Li, X | 2 |
| Sun, J | 1 |
| Wang, G | 1 |
| Zheng, Y | 1 |
| Yan, B | 1 |
| Xie, H | 1 |
| Gu, Y | 1 |
| Ren, H | 1 |
| Guo, P | 1 |
| Wang, J | 1 |
| You, A | 1 |
| Jessa, MJ | 1 |
| Barrett, DA | 1 |
| Shaw, PN | 1 |
| Spiller, RC | 1 |
| Perri, F | 1 |
| Clemente, R | 1 |
| Festa, V | 1 |
| Quitadamo, M | 1 |
| Conoscitore, P | 1 |
| Niro, G | 1 |
| Ghoos, Y | 1 |
| Rutgeerts, P | 1 |
| Andriulli, A | 1 |
| Kang, EW | 1 |
| Clinch, K | 1 |
| Furneaux, RH | 1 |
| Harvey, JE | 1 |
| Schofield, PJ | 1 |
| Gero, AM | 1 |
| Fanti, L | 1 |
| Ieri, R | 1 |
| Mezzi, G | 1 |
| Testoni, PA | 1 |
| Passaretti, S | 1 |
| Guslandi, M | 1 |
2 trials available for tinidazole and Sensitivity and Specificity
| Article | Year |
|---|---|
Relationship between the results of pre-treatment urea breath test and efficacy of eradication of Helicobacter pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Carbon Isotopes; Clarithromycin; Drug Admin | 1998 |
Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies | 2001 |
10 other studies available for tinidazole and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous quantification of linezolid, tinidazole, norfloxacin, moxifloxacin, levofloxacin, and gatifloxacin in human plasma for therapeutic drug monitoring and pharmacokinetic studies in human volunteers.
Topics: Acetamides; Adult; Anti-Infective Agents; Aza Compounds; Chromatography, High Pressure Liquid; Drug | 2013 |
A simple high-performance liquid chromatographic method for the determination of brazilin and its application to a pharmacokinetic study in rats.
Topics: Animals; Area Under Curve; Benzopyrans; Chromatography, High Pressure Liquid; Dose-Response Relation | 2014 |
Simultaneous determination of vancomycin and ceftazidime in cerebrospinal fluid in craniotomy patients by high-performance liquid chromatography.
Topics: Acetates; Acetonitriles; Anti-Bacterial Agents; Buffers; Ceftazidime; Chromatography, High Pressure | 2008 |
Dried blood spot assay for estimation of metronidazole concentrations in rats and its application in single animal drug pharmacokinetic study.
Topics: Animals; Blood Specimen Collection; Chromatography, High Pressure Liquid; Desiccation; Least-Squares | 2011 |
Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Metronidazole; Ni | 2012 |
Stability indicating methods for the determination of norfloxacin in mixture with tinidazole.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Densitometry; Drug Stability; Norfloxacin; Reference | 2007 |
Determination of secnidazole in human plasma by high-performance liquid chromatography with UV detection and its application to the bioequivalence studies.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Antiprotozoal Agents; Area Under Curve; Biologic | 2007 |
Study on the compatibility of cefotaxime with tinidazole in glucose injection.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Antitrichomonal Agents; Cefotaxi | 2007 |
Rapid and selective high-performance liquid chromatographic method for the determination of metronidazole and its active metabolite in human plasma, saliva and gastric juice.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Gastric Juice; Humans; Metronidazole; R | 1996 |
A novel and simple colorimetric method for screening Giardia intestinalis and anti-giardial activity in vitro.
Topics: Animals; Antitrichomonal Agents; Chromogenic Compounds; Colorimetry; Furazolidone; Giardia lamblia; | 1998 |