Proteins > MO15-related protein kinase Pfmrk
Page last updated: 2024-08-07 13:27:19
MO15-related protein kinase Pfmrk
[no definition available]
Synonyms
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (26)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bisindolylmaleimide i | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 24.0000 | 1 | 1 |
| chloroquine | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 150.0000 | 1 | 1 |
| n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 70.0000 | 1 | 1 |
| n-(2-aminoethyl)-5-isoquinolinesulfonamide | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.7000 | 1 | 1 |
| 1-(5-isoquinolinesulfonyl)piperazine | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| ha 1004 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| fasudil | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| indirubin-3'-monoxime | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 30.0000 | 2 | 2 |
| nsc 664704 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 15.0000 | 2 | 2 |
| mefloquine hydrochloride | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 12.0000 | 1 | 1 |
| ml 7 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| ml 9 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| olomoucine | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1,050.0000 | 2 | 2 |
| w 7 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| whi p180 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 168.0000 | 1 | 1 |
| staurosporine | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 4.0000 | 2 | 2 |
| cyc 202 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1,000.0000 | 1 | 1 |
| h 89 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| purvalanol a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 26.0000 | 1 | 1 |
| 5-Nitroisatin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.9000 | 1 | 1 |
| alsterpaullone | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 51.0000 | 2 | 2 |
| apigenin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 7.0000 | 1 | 1 |
| genistein | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 93.0000 | 1 | 1 |
| myricetin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 157.0000 | 1 | 1 |
| 4'-acetamidochalcone | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 17.0000 | 2 | 2 |
| butyrolactone i | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 94.0000 | 1 | 1 |
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.Journal of medicinal chemistry, , Aug-28, Volume: 46, Issue:18, 2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.Journal of medicinal chemistry, , Aug-28, Volume: 46, Issue:18, 2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.Journal of medicinal chemistry, , Aug-28, Volume: 46, Issue:18, 2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.Journal of medicinal chemistry, , Aug-28, Volume: 46, Issue:18, 2003
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.Journal of medicinal chemistry, , Aug-28, Volume: 46, Issue:18, 2003
Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.Bioorganic & medicinal chemistry letters, , Apr-01, Volume: 19, Issue:7, 2009
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.Journal of medicinal chemistry, , Oct-21, Volume: 47, Issue:22, 2004