| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| betaine | [no description available] | medium | 8 | 0 | amino-acid betaine;
glycine derivative | fundamental metabolite |
| taurine | [no description available] | medium | 4 | 0 | amino sulfonic acid;
zwitterion | antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite |
| arsenic | [no description available] | medium | 1 | 0 | metalloid atom;
pnictogen | micronutrient |
| arsenobetaine | [no description available] | medium | 1 | 0 | organic salt | |
| trimethyloxamine | [no description available] | medium | 3 | 0 | tertiary amine oxide | Escherichia coli metabolite;
metabolite;
osmolyte |
| dimethylpropiothetin | [no description available] | medium | 2 | 0 | sulfonium betaine | marine metabolite;
osmolyte |
| isethionic acid | [no description available] | medium | 1 | 0 | alkanesulfonic acid | human metabolite |
| proline | [no description available] | medium | 1 | 0 | amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid | algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| niacin | [no description available] | medium | 3 | 0 | pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3 | antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent |
| trigonelline | [no description available] | medium | 9 | 0 | alkaloid;
iminium betaine | food component;
human urinary metabolite;
plant metabolite |
| succinic acid | [no description available] | medium | 2 | 0 | alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid | anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent |
| lysine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| choline | [no description available] | medium | 5 | 0 | cholines | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| guanidinoethane sulfonate | [no description available] | medium | 1 | 0 | guanidines;
organosulfonic acid;
zwitterion | |
| glycine | [no description available] | medium | 5 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
| ergothioneine | [no description available] | medium | 1 | 0 | 1,3-dihydroimidazole-2-thiones;
amino-acid betaine;
L-histidine derivative;
sulfur-containing amino acid | antioxidant;
chelator;
fungal metabolite;
plant metabolite;
xenobiotic metabolite |
| adenine | [no description available] | medium | 1 | 0 | 6-aminopurines;
purine nucleobase | Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| histidine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| trimethylamine | [no description available] | medium | 1 | 0 | methylamines;
tertiary amine | Escherichia coli metabolite;
human xenobiotic metabolite |
| picolinic acid | [no description available] | medium | 3 | 0 | pyridinemonocarboxylic acid | human metabolite;
MALDI matrix material |
| phenyl acetate | [no description available] | medium | 3 | 0 | benzenes;
phenyl acetates | |
| propionic acid | [no description available] | medium | 1 | 0 | saturated fatty acid;
short-chain fatty acid | antifungal drug |
| lactic acid | [no description available] | medium | 2 | 0 | 2-hydroxy monocarboxylic acid | algal metabolite;
Daphnia magna metabolite |
| acetic acid | [no description available] | medium | 1 | 0 | monocarboxylic acid | antimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent |
| acrylic acid | [no description available] | medium | 1 | 0 | alpha,beta-unsaturated monocarboxylic acid | metabolite |
| putrescine | [no description available] | medium | 1 | 0 | alkane-alpha,omega-diamine | antioxidant;
fundamental metabolite |
| hydroxylysine | [no description available] | medium | 1 | 0 | 5-hydroxylysine;
hydroxy-L-lysine | human metabolite |
| arginine | [no description available] | medium | 2 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
| histamine | [no description available] | medium | 1 | 0 | aralkylamino compound;
imidazoles | human metabolite;
mouse metabolite;
neurotransmitter |
| acetoacetic acid | [no description available] | medium | 1 | 0 | 3-oxo fatty acid;
ketone body | metabolite |
| pukalide | [no description available] | medium | 1 | 0 | | |
| succinyl-coenzyme a | [no description available] | medium | 1 | 0 | omega-carboxyacyl-CoA | Escherichia coli metabolite;
inhibitor;
mouse metabolite |
| sinefungin | [no description available] | medium | 1 | 0 | adenosines;
non-proteinogenic alpha-amino acid | antifungal agent;
antimicrobial agent |
| s-adenosylhomocysteine | [no description available] | medium | 1 | 0 | adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide | cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite |
| adenosine | [no description available] | medium | 1 | 0 | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent |
| s-adenosylmethionine | [no description available] | medium | 1 | 0 | organic cation;
sulfonium compound | coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| serine | [no description available] | medium | 1 | 0 | L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| aspartic acid | [no description available] | medium | 2 | 0 | aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
mouse metabolite;
neurotransmitter |
| kynurenine | [no description available] | medium | 1 | 0 | aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline | human metabolite |
| tryptophan | [no description available] | medium | 2 | 0 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| methionine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid | antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
| glycerol | [no description available] | medium | 1 | 0 | alditol;
triol | algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent |
| hydrogen carbonate | [no description available] | medium | 1 | 0 | carbon oxoanion | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
| retinol | [no description available] | medium | 1 | 0 | retinol;
vitamin A | human metabolite;
mouse metabolite;
plant metabolite |
| tetramethylammonium | [no description available] | medium | 1 | 0 | quaternary ammonium ion | |
| 3-chloroalanine | [no description available] | low | 0 | 0 | chloroalanine;
non-proteinogenic alpha-amino acid;
organochlorine compound | |
| phosphoserine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative | human metabolite |
| 2-amino-3-ketobutyrate | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid;
non-proteinogenic alpha-amino acid | |
| 2,3-diaminopropionic acid | [no description available] | low | 0 | 0 | alanine derivative;
amino acid zwitterion;
beta-amino acid;
diamino acid;
non-proteinogenic alpha-amino acid | Escherichia coli metabolite |
| 2-aminoadipic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
dicarboxylic fatty acid;
non-proteinogenic alpha-amino acid | Caenorhabditis elegans metabolite;
mammalian metabolite |
| 2,4-diaminobutyric acid | [no description available] | low | 0 | 0 | diamino acid;
gamma-amino acid;
non-proteinogenic alpha-amino acid | |
| 1-aminocyclopropane-1-carboxylic acid | [no description available] | low | 0 | 0 | amino acid zwitterion;
monocarboxylic acid;
non-proteinogenic alpha-amino acid | ethylene releasers;
plant metabolite |
| dihydroxyphenylalanine | [no description available] | low | 0 | 0 | hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | human metabolite |
| thyroxine | [no description available] | low | 0 | 0 | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | mitogen |
| 2-amino-5-phosphonovalerate | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | NMDA receptor antagonist |
| alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| ibotenic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | neurotoxin |
| cycloleucine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | EC 2.5.1.6 (methionine adenosyltransferase) inhibitor |
| 2-amino-3-phosphonopropionic acid | [no description available] | low | 0 | 0 | alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids | human metabolite;
metabotropic glutamate receptor antagonist |
| 2-phenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | human metabolite |
| p-fluorophenylalanine | [no description available] | low | 0 | 0 | fluoroamino acid;
monofluorobenzenes;
non-proteinogenic alpha-amino acid;
phenylalanine derivative | |
| penicillamine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
thiol | |
| penicillamine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
penicillamine | antirheumatic drug;
chelator;
copper chelator;
drug allergen |
| iminodiacetic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
glycine derivative;
non-proteinogenic alpha-amino acid | chelator |
| 2-fluorophenylalanine | [no description available] | low | 0 | 0 | monofluorobenzenes;
non-proteinogenic alpha-amino acid;
phenylalanine derivative | |
| 5-fluorotryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
organofluorine compound;
tryptophan derivative | |
| thiazolidine-4-carboxylic acid | [no description available] | low | 0 | 0 | alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
sulfur-containing amino acid;
thiazolidinemonocarboxylic acid | antidote;
antioxidant;
hepatoprotective agent |
| 3-cyanoalanine | [no description available] | low | 0 | 0 | alanine derivative;
aliphatic nitrile;
non-proteinogenic alpha-amino acid | |
| methionine sulfoximine | [no description available] | low | 0 | 0 | methionine derivative;
non-proteinogenic alpha-amino acid;
sulfoximide | |
| buthionine sulfoximine | [no description available] | low | 0 | 0 | diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide | EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer |
| cysteic acid | [no description available] | low | 0 | 0 | alanine derivative;
amino sulfonic acid;
carboxyalkanesulfonic acid;
cysteine derivative;
non-proteinogenic alpha-amino acid | animal metabolite |
| quisqualic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| cilazaprilat | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 3-hydroxynorvaline | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
non-proteinogenic amino acid derivative | |
| n-phenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | allergen |
| selfotel | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 2-(methylamino)isobutyric acid | [no description available] | low | 0 | 0 | alanine derivative;
alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
secondary amino compound | human urinary metabolite |
| 2-tyrosine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
phenols;
phenylalanine derivative | |
| 3-fluorotyrosine | [no description available] | low | 0 | 0 | fluoroamino acid;
fluorophenol;
non-proteinogenic alpha-amino acid;
tyrosine derivative | |
| triazolealanine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
triazoles | |
| 5-methyltryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
tryptophan derivative | |
| 4-methyleneglutamic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 1-methyltryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
tryptophan derivative | antineoplastic agent;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor |
| alpha-aminopimelic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
non-proteinogenic alpha-amino acid | bacterial metabolite |
| lanthionine | [no description available] | low | 0 | 0 | alanine derivative;
non-proteinogenic alpha-amino acid;
organic sulfide | bacterial metabolite |
| 6-hydroxydopa | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| dityrosine | [no description available] | low | 0 | 0 | biphenyls;
non-proteinogenic alpha-amino acid;
tyrosine derivative | biomarker |
| selenomethylselenocysteine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
selenocysteines | antineoplastic agent;
human metabolite |
| dehydroalanine | [no description available] | low | 0 | 0 | 2,3-dehydroamino acid;
alpha,beta-unsaturated monocarboxylic acid;
amino acid zwitterion;
enamine;
non-proteinogenic alpha-amino acid | alkylating agent;
human metabolite;
mouse metabolite |
| (tetrazol-5-yl)glycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| delta-n-hydroxyornithine | [no description available] | low | 0 | 0 | amino acid zwitterion;
hydroxylamines;
L-ornithine derivative;
non-proteinogenic alpha-amino acid | |
| melagatran | [no description available] | low | 0 | 0 | azetidines;
carboxamidine;
dicarboxylic acid monoamide;
non-proteinogenic alpha-amino acid;
secondary amino compound | anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
serine protease inhibitor |
| 3-nitrotyrosine | [no description available] | low | 0 | 0 | 2-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid | |
| 5',5',5'-trifluoroleucine | [no description available] | low | 0 | 0 | leucine derivative;
non-proteinogenic alpha-amino acid;
organofluorine compound | |
| azaleucine | [no description available] | low | 0 | 0 | alanine derivative;
leucine derivative;
non-proteinogenic alpha-amino acid;
tertiary amino compound | |
| 2-amino-3,3-dimethylbutanoic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabolite |
| cucumopine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| cucurbitine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| temocaprilat | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| alpha-methyl-4-carboxyphenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabotropic glutamate receptor antagonist |
| serine ethanolamine phosphate | [no description available] | low | 0 | 0 | amino acid zwitterion;
non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
phosphoethanolamine;
serine derivative | |
| indicaxanthin | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| thermozymocidin | [no description available] | low | 0 | 0 | alpha-amino fatty acid;
hydroxy monocarboxylic acid;
non-proteinogenic alpha-amino acid;
sphingoid | antifungal agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor;
fungal metabolite;
immunosuppressive agent |
| argpyrimidine | [no description available] | low | 0 | 0 | hydroxypyrimidine;
L-arginine derivative;
non-proteinogenic alpha-amino acid | epitope |
| brasilicardin a | [no description available] | low | 0 | 0 | benzoate ester;
carbotricyclic compound;
diterpenoid;
N-acetyl-D-glucosaminide;
non-proteinogenic alpha-amino acid;
phenols | antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
immunosuppressive agent |
| 4-formylaminooxyvinylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabolite |