Page last updated: 2024-12-05

glyphosate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Glyphosate is a broad-spectrum herbicide used to kill weeds. It works by inhibiting the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which is essential for the synthesis of aromatic amino acids in plants. Glyphosate was first synthesized in 1950 by Monsanto, and it was introduced as a herbicide in 1974 under the trade name Roundup. Glyphosate is the most widely used herbicide in the world, and it is applied to a wide variety of crops, including corn, soybeans, wheat, and cotton. It is also used for weed control in lawns, gardens, and other non-crop areas. Glyphosate is a non-selective herbicide, meaning that it can kill any type of plant. It is absorbed through the roots and leaves of plants, and it can also be taken up by the soil. Glyphosate is relatively non-toxic to mammals, but it can cause eye and skin irritation. Glyphosate has been the subject of much research and controversy, with some studies suggesting that it may be linked to cancer and other health problems. However, other studies have found no evidence of such links. The safety of glyphosate is still being debated, and more research is needed to fully understand its effects on human health and the environment.'

glyphosate: active cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

glyphosate : A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS). [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID3496
CHEMBL ID95764
CHEBI ID27744
SCHEMBL ID16440
MeSH IDM0056912

Synonyms (171)

Synonym
CHEMBL95764 ,
2-(phosphonatomethylammonio)acetate
accord
4632ww1x5a ,
glyphodin a
ground bio
glyphomax
safal
gliz
glyfos
carboxymethylaminomethanephosphinic acid
hm 2028
unii-4632ww1x5a
buccaneer plus
leone
glialka 36
forsat
lancer (herbicide)
rebel garden
glifoglex
herbatop
atila
c-k yuyos fav
glygran
buccaneer
klinik
phosphonomethylglycine
phorsat
gliz 480cs
glifosan 747
kickdown
hockey
folusen
glyphosate ct
mon 3539
CHEBI:27744 ,
2-(phosphonomethylamino)acetic acid
n-(phosphonomethyl) glycine
KBIO1_001518
DIVK1C_006574
(carboxymethylamino)methylphosphonic acid
pondmaster
sting
mon 6000
spasor
sonic
n-phosphomethylglycine
glialka
tumbleweed
phosphonomethyliminoacetic acid
SPECTRUM_001867
((phosphonomethyl)amino)acetic acid
BSPBIO_002397
NCGC00014409
gpj ,
brn 2045054
silglif
roundup max
hsdb 3432
caswell no. 661a
gliphosate
ccris 1587
glyphosate [ansi:bsi:iso]
nsc 151063
epa pesticide chemical code 417300
einecs 213-997-4
C01705
glyphosate
roundup (tn)
1071-83-6
glyphosphate
wln: qv1m1pqqo
mon 39
glycine, n-(phosphonomethyl)-
nsc-151063
n-(phosphonomethyl)glycine
n-phosphonomethylglycine
mon 0573
glyphosate, isopropylamine salt
cp 70139
nsc151063 ,
mon 2139
cp 67573
glifonox
n-(phosphonomethyl)glycine, plant cell culture tested, bioreagent
2GGD
2GGA
n-(phosphonomethyl)glycine, 96%
NCI151063
NCGC00094536-01
NCGC00094536-02
KBIO2_007516
KBIO2_002380
KBIO2_004948
KBIO3_001897
KBIOGR_001117
KBIOSS_002384
NCI60_001060
NCISTRUC2_000104
SPECTRUM3_000839
SPBIO_001634
SPECTRUM2_001847
SPECPLUS_000478
SPECTRUM4_000679
NCISTRUC1_000002
SPECTRUM330047
SPECTRUM5_001992
[(phosphonomethyl)amino]acetic acid
NCGC00094536-03
GPF ,
86491FAD-2F76-4CDE-90EE-6131D3FCF0BB
n-(phosphonomethyl)-glycine
FT-0651304
inchi=1/c3h8no5p/c5-3(6)1-4-2-10(7,8)9/h4h,1-2h2,(h,5,6)(h2,7,8,9)
xddaorkbjwwyjs-uhfffaoysa-
bdbm50281349
A801602
2-(phosphonomethylamino)ethanoic acid
AKOS004915878
CCG-38069
NCGC00014409-02
NCGC00014409-03
NCGC00014409-04
2-[(phosphonomethyl)amino]acetic acid
994-61-6
n-phosphonomethyl-glycine
SCHEMBL16440
KS-5110
glyphosate [mart.]
glyphosate [mi]
glyphosate [iso]
glyphosate [iarc]
glyphosate [hsdb]
phosphonomethyl glycine
n-phosphonomethyl glycine
Q-201175
2-((phosphonomethyl)amino)acetic acid
hm 2028; herbatop; hockey; kickdown; klinik;nsc 151063
DTXSID1024122 ,
glyphosate, certified reference material, tracecert(r)
glyphosate, pestanal(r), analytical standard
glyphosate 10 microg/ml in water
glyphosate 100 microg/ml in water
glyphosate (n-(phosphonomethyl)glycine) 100 microg/ml in water
glyphosat
Q407232
mfcd00055350
AMY22521
BCP32091
glyphosate [m+h+]
H10288
EN300-187560
CS-0012877
glyfosate 13c2 15n
HY-B0863
mon-0573
glifinox
gliialka
usepa/opp pesticide code: 417300
biotox pest detox
glyphosate (mart.)
mon 0468
glyphosate (iarc)
dtxcid004122
Z3225522739
837 - pesticides in citrus fruits
840 - pesticides in pulses
841 - pesticides in cereals
836 - pesticides in pome fruits
838 - pesticides in fruiting vegetables
839 - pesticides in root and tuber vegetables

Research Excerpts

Overview

Glyphosate (Roundup) is an herbicide used extensively worldwide. It acts as an inhibitor of 5'enolpyruvylshikimate-3-phosphate synthase and for which transgenic herbicide resistant plants have been developed.

ExcerptReferenceRelevance
"Glyphosate (Roundup) is an herbicide used extensively worldwide which acts as an inhibitor of 5'enolpyruvylshikimate-3-phosphate synthase and for which transgenic herbicide resistant plants have been developed. "( Glyphosate is an inhibitor of plant cytochrome P450: functional expression of Thlaspi arvensae cytochrome P45071B1/reductase fusion protein in Escherichia coli.
Hanley, SZ; Kelly, DE; Kelly, SL; Lamb, DC; Mehmood, Z, 1998
)
3.19
"Glyphosate is an herbicide widely used in agricultural activities causing contamination of soils and bodies of water and damage to the biodiversity of ecosystems. "( Interaction of glyphosate in matrices of cellulose and diethylaminoethyl cellulose biopolymers: theoretical viewpoint of the adsorption process.
Cavallini, GS; Costa, AMF; de Aguiar Filho, SQ; Dos Santos Pereira, AK; Pereira, DH, 2021
)
2.42
"Glyphosate is a broad-spectrum herbicide that inactivates the 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) enzyme and causes plant death."( Rapeseed Transformation with aroA Bacterial Gene Containing P101S Mutation Confers Glyphosate Resistance.
Kahrizi, D; Roeintan, A; Safavi, SM, 2022
)
1.67
"Glyphosate is a highly effective, low-toxicity, broad-spectrum herbicide, which is extensively used in global agriculture to control weeds and vegetation. "( NPA-Cu
Fu, Y; Li, P; Liu, YL; Sun, F; Wang, YB; Yang, L; Ye, XL; Yue, ML, 2021
)
2.06
"Glyphosate is a broad-spectrum, non-selective systemic herbicide. "( Transcriptome analysis reveals differing response and tolerance mechanism of EPSPS and GAT genes among transgenic soybeans.
Guo, BF; Guo, Y; Hong, HL; Qiu, LJ; Sun, LP, 2021
)
2.06
"Glyphosate (GLYP) is a widely used pesticide; it is considered to be a safe herbicide for animals and humans because it targets 5-enolpyruvylshikimate-3-phosphate synthase. "( Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology.
Anadón, A; Ares, I; Guo, J; Lu, Q; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Wang, X, 2022
)
2.41
"Glyphosate is a widely used herbicide in global agriculture. "( The association between urinary glyphosate and aminomethyl phosphonic acid with biomarkers of oxidative stress among pregnant women in the PROTECT birth cohort study.
Alshawabkeh, A; Cathey, AL; Cordero, J; Eaton, JL; Fernandez, JA; Meeker, JD; Milne, GL; Rosario, Z; Silver, MK; Velez-Vega, C; Watkins, DJ, 2022
)
2.45
"Glyphosate (GLP) is a broad-spectrum herbicide that is frequently used in crop production, but its residues remain in foodstuffs. "( Ameliorative effect of N-acetylcysteine on the testicular tissue of adult male albino rats after glyphosate-based herbicide exposure.
Bashir, DW; El-Gharbawy, SM; Hashim, AR; Rashad, MM; Yasin, NAE, 2022
)
2.38
"Glyphosate is a broad-spectrum and nonselective organophosphorus herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), an enzyme in the shikimate pathway in plants. "( Isolation of a degrading strain of Fusarium verticillioides and bioremediation of glyphosate residue.
Guo, J; Li, Q; Li, R; Song, X; Tao, B; Zhang, Q; Zheng, S, 2022
)
2.39
"Glyphosate is a component of commonly used herbicides for controlling weeds in crops, gardens and municipal parks. "( Metabolomic and Transcript Analysis Revealed a Sex-Specific Effect of Glyphosate in Zebrafish Liver.
Carnevali, O; Giommi, C; Habibi, HR; Ladisa, C; Maradonna, F, 2022
)
2.4
"Glyphosate (GBH) is a worldwide consumption pesticide and is used in the formulation of Roundup®, one of the most commercialized herbicides in the world. "( Maternal exposure to glyphosate-based herbicide promotes changes in the muscle structure of C57BL/6 mice offspring.
Barbosa, A; Bonfleur, ML; Costa, RM; Oliveira, MC; Teleken, JL; Torrejais, MM; Zazula, MF, 2022
)
2.48
"Glyphosate is a widely used herbicide with an annual production of more than one million tons globally. "( Harnessing phosphonate antibiotics argolaphos biosynthesis enables a synthetic biology-based green synthesis of glyphosate.
Cao, Y; Chu, L; Deng, Z; Gao, J; Luo, X; Zhang, L; Zhu, T, 2022
)
2.38
"Glyphosate (GLY) is a broad-spectrum herbicide that is the most commonly applied pesticide in terrestrial ecosystems in the U.S. "( Pesticides in a warmer world: Effects of glyphosate and warming across insect life stages.
D, B; Evalen, P; Stahlschmidt, ZR; Vo, C; Whitlock, J, 2022
)
2.43
"Glyphosate is a universal herbicide with genital toxicity, but the effect of glyphosate on oocytes has not been reported. "( Glyphosate decreases bovine oocyte quality by inducing oxidative stress and apoptosis.
E, Z; Gao, Q; Jin, Q; Sun, J; Zhang, X; Zhao, Y, 2022
)
3.61
"Glyphosate is a herbicide that acts as a broad-spectrum, non-selective, post-emergence systemic pest controller. "( Degradation of commercial glyphosate-based herbicide via advanced oxidative processes in aqueous media and phytotoxicity evaluation using maize seeds.
da Silva, VEC; Forti, JC; Putti, FF; Santos, FA; Tadayozzi, YS, 2022
)
2.46
"Glyphosate is a dominant organophosphate herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) of the shikimate pathway. "( Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona.
Chen, CC; Dai, L; Guo, RT; Hu, Y; Huang, JW; Li, H; Min, J; Yang, Y, 2022
)
2.4
"Glyphosate is a herbicide which is commonly used in agricultural areas. "( Effects of exposure to glyphosate on oxidative stress, inflammation, and lung function in maize farmers, Northern Thailand.
Khacha-Ananda, S; Pothirat, C; Sapbamrer, R; Sidthilaw, S; Wunnapuk, K, 2022
)
2.47
"Glyphosate (Gly) is a globally spread herbicide that can cause toxic injuries to hepatocytes. "( Trehalose prevents glyphosate-induced hepatic steatosis in roosters by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation.
Lian, CY; Wang, J; Wang, L; Wang, RZ; Wang, ZY; Zhang, W, 2023
)
2.68
"Glyphosate is a pesticide, which contaminates the environment and exposes workers and general population to its residues present in foods and waters. "( In vitro study of glyphosate effects on thyroid cells.
Chiovato, L; Coperchini, F; Croce, L; Denegri, M; Greco, A; Magri, F; Rotondi, M, 2023
)
2.69
"Glyphosate is a pesticide considered of low toxicity, but scientific evidences show it can be harmful to health. "( Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring.
Aragão, GF; Assreuy, AMS; Braga, MDM; Chaves, EMC; de Castro Vieira Carneiro, CL; de Moraes, MEA; Neves, KRT, 2023
)
2.6
"Glyphosate is a widely used herbicide and crop desiccant. "( The effects of glyphosate exposure on gene transcription and immune function of the silkworm, Bombyx mori.
Feng, P; Hu, Y; Li, B; Liu, W; Ren, Y; Shu, Q; Su, W; Wang, Y; Zhu, Q; Zou, H, 2023
)
2.71
"Glyphosate (GLYP) is a broad-spectrum, nonselective, organic phosphine postemergence herbicide registered for many food and nonfood fields. "( A Novel Fluorescent Sensor Based on Aptamer and qPCR for Determination of Glyphosate in Tap Water.
Abd El-Aty, AM; Cao, J; Cao, Z; Duan, J; Jin, F; Li, G; Shao, Y; She, Y; Tian, R; Wang, M, 2023
)
2.58
"Glyphosate is a broad-spectrum herbicide applied in agricultural and non-agricultural settings."( Glyphosate exposure and preterm birth: A nested case-control pilot study.
Bloom, MS; Braak, DC; Gerona, RR; Newman, RB; Reckers, A; Varde, M; Vena, JE, 2023
)
3.07
"Glyphosate is a herbicide widely used in food production that blocks the synthesis of aromatic amino acids in plants and in microorganisms and also induces the accumulation of the alarmone (p)ppGpp. "( Glyphosate affects persistence and tolerance but not antibiotic resistance.
Ospino, K; Spira, B, 2023
)
3.8
"Glyphosate is a nonselective and postemergent herbicide used to combat weeds in several crops, which raises concerns about risks to human health since residues are detected in urine, human milk, surface water and several types of food. "( Prepubertal to adulthood exposure to low doses of glyphosate-based herbicide increases the expression of the Havcr1 (Kim1) biomarker and causes mild kidney alterations.
Bender, JMO; Gadotti, CP; Lima, MDFS; Oliveira, JM; Quináia, SP; Romano, MA; Romano, RM; Taques, GR, 2023
)
2.61
"As glyphosate is a broad-spectrum herbicide extensively used in agriculture worldwide, rapid glyphosate detection is essential for food safety and human health. "( Ratio fluorescence test strip visualized by amino-functionalized metal-organic framework for rapid sensing of glyphosate.
Pang, YH; Shen, XF; Wan, CQ; Zhai, YS, 2023
)
1.74
"Glyphosate is a widely used herbicide that has deleterious effects on animal reproduction. "( Integrated metabolomics and transcriptomics reveal glyphosate based-herbicide induced reproductive toxicity through disturbing energy and nucleotide metabolism in mice testes.
Dong, Y; Li, G; Li, Y; Ma, S; Qi, L, 2023
)
2.6
"Glyphosate is an herbicide commonly used worldwide, and its substantial use causes widespread pollution with runoff. "( Glyphosate induces autophagy in hepatic L8824 cell line through NO-mediated activation of RAS/RAF/MEK/ERK signaling pathway and energy metabolism disorders.
Chen, L; Hong, H; Ni, X; Qi, M; Xu, H; Xu, S; Yu, F; Zhang, L, 2023
)
3.8
"Glyphosate is an herbicide commonly used in agriculture, and its widespread use has adversely affected the survival of nontarget organisms. "( Fox transcription factor AccGRF1 in response to glyphosate stress in Apis cerana cerana.
Guo, XQ; Huang, YY; Niu, XJ; Sun, YH; Wang, C; Wang, LJ; Wang, Y; Xu, BH, 2023
)
2.61
"Glyphosate is an active ingredient in herbicides. "( Adhesion Molecules in Lung Inflammation from Repeated Glyphosate Exposures.
Aulakh, G; Kirychuk, S; Pandher, U; Schneberger, D; Sethi, RS; Singh, B; Thompson, B, 2023
)
2.6
"Glyphosate is a popular and extremely effective herbicide for weed control in grain crops that inhibits the shikimate pathway."( Glyphosate potentiates insulin resistance in skeletal muscle through the modulation of IRS-1/PI3K/Akt mediated mechanisms: An in vivo and in silico analysis.
Alshuniaber, MA; Elrobh, M; Gatasheh, MK; Jayaraman, S; Krishnamoorthy, K; Krishnamoorthy, R; Prasad, M; Veeraraghavan, VP, 2023
)
3.07
"Glyphosate (GLY) is an herbicide used for rural and urban weed control. "( Maternal pre-conceptional glyphosate exposure impacts the offspring hepatic and ovarian proteome.
Keating, AF; Novbatova, G; Sayadi, M; Severin, A; Timme, K, 2023
)
2.65
"Glyphosate is a broad-spectrum and one of the most widely used herbicides in the world, which has led to its high environmental dissemination. "( Occurrence and exposure assessment of glyphosate in the environment and its impact on human beings.
Calaf, GM; Carrillo-Beltrán, D; Muñoz, JP; Silva-Pavez, E, 2023
)
2.62
"Glyphosate is a broad-spectrum systemic herbicide widely used in crops to control weeds and could affect honeybees' health in sublethal doses."( Sublethal doses of glyphosate modulates mitochondria and oxidative stress in honeybees by direct feeding.
Herrera, C; Leza, M; Pons, DG; Sastre-Serra, J; Torrens-Mas, M, 2023
)
1.96
"Glyphosate is a broad-spectrum pesticide used in crops and is found in many products used by industry and consumers. "( Ratiometric Sensing of Glyphosate in Water Using Dual Fluorescent Carbon Dots.
Clermont-Paquette, A; Mendoza, DA; Naccache, R; Piekny, A; Sadeghi, A, 2023
)
2.66
"Glyphosate (Glyp) is an organophosphorus herbicide, and its abuse causes potential harm to the environment and human health. "( A novel Cu(II)-assisted peptide fluorescent probe for highly sensitive detection of glyphosate in real samples: real application in test strips and smartphone.
Hou, P; Wang, P; Wang, Q; Wei, P; Xiao, L, 2023
)
2.58
"Glyphosate is a broad-spectrum, non-selective herbicide used to control weeds and protect agricultural crops, and it is classified as potentially carcinogenic by the International Agency for Research on Cancer. "( GLYPHOSATE IMPACT on human health and the environment: Sustainable alternatives to replace it in Mexico.
González-Moscoso, M; Martínez-Villegas, NV; Meza-Figueroa, D; Pedroza-Montero, MR, 2023
)
3.8
"Glyphosate is a herbicide commonly used in agriculture for weed control. "( Biomarkers of pollution by glyphosate in the lichens, Parmotrema tinctorium and Usnea barbata.
Augusto, DSS; Batista, PF; Bessa, LA; Santos, AMD; Vasconcelos Filho, SC; Vitorino, LC, 2023
)
2.65
"Glyphosate is an organophosphorus compound, and its detection in complex matrices usually requires laborious pretreatment."( Direct glyphosate soil monitoring at the triazine-based covalent organic framework with the theoretical study of sensing principle.
Ajdačić, V; Costache, V; Jovanović, NT; Knežević, S; Opsenica, I; Stanković, D; Vidić, J; Vlahović, F, 2023
)
2.09
"Glyphosate is a widely-used herbicide that shows toxicity to non-target organisms. "( Glyphosate decreases survival, increases fecundity, and alters the microbiome of the natural predator Harmonia axyridis (ladybird beetle).
Cui, H; Cui, J; Gao, X; Hu, F; Ji, J; Li, D; Luo, J; Wang, L; Zhang, K; Zhu, X, 2023
)
3.8
"Glyphosate is an herbicide extensively used worldwide that can remain in the soil. "( Capability of phytoremediation of glyphosate in environment by Vulpia myuros.
Gao, W; Hou, R; Li, Y; Lin, M; Mao, J; Xing, B; Zhang, Y, 2023
)
2.63
"Glyphosate (GLY) is a widely used herbicide with potential adverse effects on public health. "( Association of glyphosate exposure with multiple adverse outcomes and potential mediators.
Huang, G; Jiang, L; Lei, D; Li, W; Lin, Y; Lu, P; Lv, J; Qin, YJ; Tang, N; Xu, F, 2023
)
2.71
"Glyphosate is a nonselective systemic herbicide used in agriculture since 1974. "( Glyphosate in livestock: feed residues and animal health1.
Karberg, KA; Reeves, WR; Swarthout, JT; Vicini, JL, 2019
)
3.4
"Glyphosate is a chemical compound used mainly as a broad spectrum herbicide, it is recognized for its proven effectiveness and easy handling. "( Cytotoxic evaluation of glyphosate, using Allium cepa L. as bioindicator.
Caleño, JDQ; Mercado, SAS, 2020
)
2.31
"Glyphosate is a broad-spectrum pesticide that is widely used in agricultural production."( Toxic effects of glyphosate on intestinal morphology, antioxidant capacity and barrier function in weaned piglets.
Bai, G; Fu, H; Qiu, S; Shi, B; Yang, Z; Zhou, R, 2020
)
1.62
"Glyphosate is a broad-spectrum, non-selective, post-emergence herbicide that controls weeds by inhibiting their ability to synthesize amino acids. "( Investigation of the presence of glyphosate and its major metabolite AMPA in Greek soils.
Karasali, H; Marousopoulou, A; Pavlidis, G, 2019
)
2.24
"Glyphosate (GP) is a widely used herbicide worldwide, yet accumulation of GP and its main byproduct, aminomethylphosphonic acid (AMPA), in soil and water has raised concerns about its potential effects on human health. "( Thermal decomposition kinetics of glyphosate (GP) and its metabolite aminomethylphosphonic acid (AMPA).
da Silva, G; Narimani, M, 2020
)
2.28
"Glyphosate is a widely used herbicide worldwide. "( The Potential Effects of Recall Bias and Selection Bias on the Epidemiological Evidence for the Carcinogenicity of Glyphosate.
Crump, K, 2020
)
2.21
"Glyphosate (GLY) is a broad-spectrum, post-emergent, non-selective and synthetic universal herbicide, whose commercial formulations are referred to as glyphosate-based-herbicides (GBHs). "( Effects of glyphosate exposure on human health: Insights from epidemiological and in vitro studies.
Agostini, LP; Cardoso, RC; Dettogni, RS; Dos Reis, RS; Dos Santos, EVW; Garcia, FM; Graceli, JB; Louro, ID; Stur, E; Ventorim, DP, 2020
)
2.39
"Glyphosate is a widely used pesticide worldwide. "( Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.).
Chen, L; Li, S; Liu, Q; Wang, W; Xu, S; Zhang, T, 2020
)
3.44
"Glyphosate is an herbicide that inhibits the growth of weed plants, while chlorpyrifos is an insecticide commonly applied to control the pests' population. "( Combined effects of exposure to sub-lethal concentration of the insecticide chlorpyrifos and the herbicide glyphosate on the biochemical changes in the freshwater crayfish Pontastacus leptodactylus.
Akhlaghi, M; Banaee, M; Gholamhosseini, A; Rakhshaninejad, M; Soltanian, S; Sureda, A, 2020
)
2.21
"Glyphosate (Gly) is a broad-spectrum herbicide and currently one of the most studied pesticides. "( Glyphosate and its toxicology: A scientometric review.
de Castilhos Ghisi, N; Fabrin, TMC; Oliveira, EC; Zuanazzi, NR, 2020
)
3.44
"Glyphosate is a systemic herbicide still used in many countries, though there are several known detrimental effects on animals. "( Palatability of glyphosate in ants: a field experiment reveals broad acceptance of highly polluted solutions in a Mediterranean ant.
Balzani, P; Frasconi Wendt, C; Frizzi, F; Masoni, A; Palchetti, V; Santini, G, 2020
)
2.35
"Glyphosate is a popular, systemic, broad-spectrum herbicide used in modern agriculture. "( Overexpression of improved EPSPS gene results in field level glyphosate tolerance and higher grain yield in rice.
Achary, VMM; Agarwal, A; Agrawal, PK; Borphukan, B; Fartyal, D; Manna, M; Masakapalli, SK; Panditi, V; Ram, B; Reddy, MK; Sheri, V; Teotia, D, 2020
)
2.24
"Glyphosate (GLY) is an herbicidal active ingredient and both in vitro and in vivo studies suggest that GLY alters ovarian function. "( Absence of glyphosate-induced effects on ovarian folliculogenesis and steroidogenesis.
Ganesan, S; Keating, AF; McGuire, BC, 2020
)
2.39
"Glyphosate is a broad-spectrum biocide and the active ingredient in the most widely used herbicides worldwide. "( Glyphosate in Portuguese Adults - A Pilot Study.
Calheiros, CSC; Nova, P; Silva, M, 2020
)
3.44
"Glyphosate (Gly) is an active ingredient of herbicide, its underlying toxicity on fish is still unclear. "( Effects of chronic glyphosate exposure on antioxdative status, metabolism and immune response in tilapia (GIFT, Oreochromis niloticus).
Cao, L; Du, J; Gu, Z; He, Q; Jia, R; Xu, P; Yin, G; Zheng, T, 2021
)
2.39
"Glyphosate is a widely used herbicide. "( Glyphosate-induced Delayed Pyloric Obstruction, Ulcer and Scar Changes.
Hao, JY; Huang, XJ; Jiang, T, 2020
)
3.44
"Glyphosate is a broad-spectrum herbicide widely used worldwide. "( Determination of Glyphosate in Water from a Rural Locality in México and Its Implications for the Population Based on Water Consumption and Use Habits.
Chavarin-Pineda, Y; Palchetti, I; Peña, RD; Reyes, D; Reynoso, EC; Torres, E, 2020
)
2.34
"Glyphosate is an organophosphorus herbicide that is applied to the leaves of plants and crops to kill broadleaf plants and grasses. "( ElectrochemSENSE: A platform towards field deployable direct on-produce glyphosate detection.
Dhamu, VN; Prasad, S, 2020
)
2.23
"Glyphosate is a non-specific organophosphate pesticide, which finds widespread application in shielding crops against the weeds. "( Herbicide Glyphosate: Toxicity and Microbial Degradation.
Datta, S; Dhaka, V; Dhanjal, DS; Gill, JPK; Harikumar, SL; Kapoor, D; Kumar, M; Kumar, V; Singh, J; Singh, S; Wani, AB, 2020
)
2.4
"Glyphosate is a large-spectrum herbicide that was introduced on the market in 1974. "( Glyphosate and the key characteristics of an endocrine disruptor: A review.
Bleak, TC; Calaf, GM; Muñoz, JP, 2021
)
3.51
"Glyphosate is a commonly used herbicide known for its high performance in killing certain plants and grasses; however, its use is regulated due to its harmful effects on the aquatic environment. "( Glyphosate Accelerates the Proliferation of Microcystis aeruginosa, a Dominant Species in Cyanobacterial Blooms.
Jiang, M; Sheng, Y; Wang, W, 2021
)
3.51
"Glyphosate is a commonly used non-selective herbicide in agriculture and aquafarms. "( Cardiogenic shock with first-degree heart block in a patient with glyphosate-surfactant poisoning.
Bhalla, A; Garbhapu, A; Ghosh, S; Kaur, S; Kolli, M; Tale, S, 2021
)
2.3
"Glyphosate is an herbicidal active substance (AS) entering in the composition of a large diversity of pesticide products (glyphosate-based herbicides; GBH) used in modern intensive agriculture. "( Impact of chronic exposure of rainbow trout, Oncorhynchus mykiss, to low doses of glyphosate or glyphosate-based herbicides.
Danion, M; Du-Carrée, JL; Morin, T, 2021
)
2.29
"Glyphosate (GLY) is a broad-spectrum herbicide used worldwide to control broadleaf sedge, and grass weeds to control non-specific vegetation. "( Monitoring of glyphosate-DNA interaction and synergistic genotoxic effect of glyphosate and 2,4-dichlorophenoxyacetic acid using an electrochemical biosensor.
Congur, G, 2021
)
2.42
"Glyphosate is an organophosphorus compound and the active ingredient in commonly used herbicides, whereas polyoxyethyleneamine (POEA) is a nonionic surfactant often coupled with glyphosate in these herbicides to increase their efficacy. "( Glyphosate and Polyoxyethyleneamine Ingestion Leading to Renal, Hepatic, and Pulmonary Failure.
Bigner, JA; Burney, HE; Fiester, SE; Fulcher, JW; Schammel, CMG; Teuber, JM; Ward, ME; Wheeler, JF; Wheeler, SK, 2021
)
3.51
"Glyphosate is a very effective herbicide and the main active ingredient in Roundup"( Ecotoxicological Studies on the Effect of Roundup
Pniewski, F; Sylwestrzak, Z; Zgrundo, A, 2021
)
2.06
"Glyphosate is a synthetic phosphonate compound characterized by a carbon‑phosphorus bond. "( Bacterial isolates from Argentine Pampas and their ability to degrade glyphosate.
Altabe, S; Burdisso, P; Garavaglia, BS; Gottig, N; Masotti, F; Ottado, J; Piazza, A, 2021
)
2.3
"Glyphosate (GLY) is an herbicide widely used in agriculture. "( Is glyphosate toxic to bees? A meta-analytical review.
Abati, R; Battisti, L; Costa-Maia, FM; de Castilhos Ghisi, N; Dos Reis Martinez, CB; Potrich, M; Sampaio, AR; Sofia, SH, 2021
)
2.69
"Glyphosate is a nonselective herbicide that kills weeds and other plants competing with crops. "( Molecular mechanisms underlying glyphosate resistance in bacteria.
Commichau, FM; Gibhardt, J; Hertel, R; Kuhn, R; Martienssen, M, 2021
)
2.35
"Glyphosate is a broad-spectrum herbicide that impairs testosterone synthesis in mammals. "( Glyphosate exposure attenuates testosterone synthesis via NR1D1 inhibition of StAR expression in mouse Leydig cells.
Chen, H; Dong, H; Gao, D; Jiang, H; Jin, Y; Li, Y; Ma, T; Wang, A; Wang, X; Wu, M; Yang, L; Yuan, Y; Zhang, H; Zhang, J; Zhang, Y; Zhao, L, 2021
)
3.51
"Glyphosate is a commonly used agrochemical active substance co-formulated in glyphosate-based herbicides (GBHs) whose environmental safety is still a subject of debate in the European Union. "( Immunological and metabolic effects of acute sublethal exposure to glyphosate or glyphosate-based herbicides on juvenile rainbow trout, Oncorhynchus mykiss.
Cabon, J; Danion, M; Le Du-Carrée, J; Morin, T, 2021
)
2.3
"Glyphosate is a phosphonomethyl amino acid derivative present in a number of non-selective and systemic herbicides. "( Epigenetic Changes Associated With Exposure to Glyphosate-Based Herbicides in Mammals.
Canesini, G; Lorenz, V; Milesi, MM; Ramos, JG; Rossetti, MF; Varayoud, J, 2021
)
2.32
"Glyphosate (GLY) is a broad-spectrum herbicide and is the most used pesticide worldwide. "( Electrochemical Microsensor for Microfluidic Glyphosate Monitoring in Water Using MIP-Based Concentrators.
Kieninger, J; Uka, B; Urban, GA; Weltin, A, 2021
)
2.32
"Glyphosate is a broad-spectrum systemic herbicide, which mainly acts in the phloem of weeds that compete with crop growth and is widely used in agriculture."( Synergetic toxicity of silver nanoparticle and glyphosate on wheat (Triticum aestivum L.).
Feng, L; Ke, M; Lu, T; Qian, H; Qu, Q; Xu, N; Zhang, Z, 2021
)
1.6
"Glyphosate is a very important herbicide that is widely used in the agriculture, and thus the exposure of humans to this substance and its metabolites has been noted. "( DNA damage and methylation induced by glyphosate in human peripheral blood mononuclear cells (in vitro study).
Bukowska, B; Jabłońska, E; Kwiatkowska, M; Michałowicz, J; Reszka, E; Woźniak, K, 2017
)
2.17
"Glyphosate is an efficient herbicide widely used worldwide. "( Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure.
Fu, YH; Jiang, L; Li, MH; Ruan, LY; Wang, JS; Zhao, H; Zhou, JW, 2017
)
2.13
"Glyphosate is a herbicide that acts by inhibition of the enzyme, 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), involved in the catalysis of an essential step in the biosynthesis of aromatic amino acids. "( Identification and analysis of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) gene from glyphosate-resistant Ochrobactrum intermedium Sq20.
Anwar, S; Firdous, S; Iqbal, S; Jabeen, H, 2018
)
2.14
"Glyphosate (GLY) is an herbicide widely used in the state of Campeche, located in the Mayan zone in the western Yucatan peninsula."( Glyphosate Residues in Groundwater, Drinking Water and Urine of Subsistence Farmers from Intensive Agriculture Localities: A Survey in Hopelchén, Campeche, Mexico.
Dzul-Caamal, R; Rendon-von Osten, J, 2017
)
2.62
"Glyphosate is a widely used broad-spectrum postemergent herbicide used for weed control in both agricultural and nonagricultural settings. "( Effects of spray drift of glyphosate on nontarget terrestrial plants-A critical review.
Cederlund, H, 2017
)
2.2
"Glyphosate is a widely used broad spectrum herbicide; however, this limits its use once crops are planted. "( Identification and functional analysis of a new glyphosate resistance gene from a fungus cDNA library.
Chang, SJ; Qiao, YX; Qiu, LJ; Shao, BH; Tao, B; Wang, XQ, 2017
)
2.15
"Glyphosate is a broad-spectrum systemic herbicide used worldwide. "( Glyphosate-induced oxidative stress in Arabidopsis thaliana affecting peroxisomal metabolism and triggers activity in the oxidative phase of the pentose phosphate pathway (OxPPP) involved in NADPH generation.
Corpas, FJ; da Silva, LC; de Freitas-Silva, L; Houmani, H; Palma, JM; Rodríguez-Ruiz, M, 2017
)
3.34
"Glyphosate is a broad-spectrum herbicide that is frequently detected in water bodies and is harmful to aquatic systems. "( Responses of Hydrilla verticillata (L.f.) Royle and Vallisneria natans (Lour.) Hara to glyphosate exposure.
Chai, L; Wu, Z; Yin, J; Zhong, G, 2018
)
2.15
"Glyphosate is an herbicide widely used in the world, being applied in several crops, among them soybeans. "( Occurrence of glyphosate and AMPA residues in soy-based infant formula sold in Brazil.
de Souza, APF; Rodrigues, NR, 2018
)
2.28
"Glyphosate is a non-selective organophosphate herbicide that is widely used in agriculture, but its effects on soil microbial communities are highly variable and often contradictory, especially for high dose applications. "( Glyphosate application increased catabolic activity of gram-negative bacteria but impaired soil fungal community.
Hua, X; Li, Y; Liu, Y; Müller, K; Pang, Y; Peng, X; Qi, J; Wang, H; Wang, M; Wang, Q; Yang, T; Yang, Y, 2018
)
3.37
"Glyphosate is an important herbicide worldwide, but its efficacy has been compromised where weed species have evolved glyphosate resistance. "( High Levels of Glyphosate Resistance in Conyza canadensis from Agricultural and Non-Agricultural Sites in Ohio and Iowa.
Ackley, BA; Beres, ZT; Ernst, EE; Loux, MM; Owen, MDK; Snow, AA, 2018
)
2.28
"Glyphosate is an important broad-spectrum herbicide used in agriculture and residential areas for weed and vegetation control, respectively. "( In vitro evaluation of genomic damage induced by glyphosate on human lymphocytes.
Cervella, P; Gendusa, C; Ruberto, S; Santovito, A, 2018
)
2.18
"Glyphosate is a pesticide used for occupational and non-occupational purposes. "( Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier.
Al-Ahmad, AJ; Martinez, A, 2019
)
2.35
"Glyphosate is a widely used herbicide in commercial crop production for both conventional and herbicide-resistant crops. "( Fate of Glyphosate during Production and Processing of Glyphosate-Resistant Sugar Beet ( Beta vulgaris).
Barker, AL; Dayan, FE, 2019
)
2.39
"Glyphosate is an extensively used herbicide, not only known for its effectiveness but also for its indirect impacts on non-target organisms."( Effects of glyphosate and a commercial formulation Roundup® exposures on maturation of Xenopus laevis oocytes.
Bodart, JF; Hanotel, J; Lemiere, S; Leprêtre, A; Lescuyer, A; Marchand, G; Marin, M; Slaby, S; Titran, P, 2020
)
1.67
"Glyphosate is a broad-spectrum herbicide that is used worldwide. "( Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines.
Agostini, LP; Aristizabal-Pachon, AF; Chariker, J; Detogni, RS; Louro, ID; Miller, DM; Peronni, KC; Reis, RSD; Rezzoug, F; Silva Junior, WA; Stur, E; Thomas, SD; Waigel, S, 2019
)
3.4
"Glyphosate is a high-efficiency, low-toxicity, broad-spectrum herbicide. "( The toxic effects and possible mechanisms of glyphosate on mouse oocytes.
Feng, XZ; Xu, DQ; Zhang, JW, 2019
)
2.22
"Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. "( Glyphosate induces human breast cancer cells growth via estrogen receptors.
Rangkadilok, N; Satayavivad, J; Suriyo, T; Thiantanawat, A; Thongprakaisang, S, 2013
)
3.28
"Glyphosate is a broad spectrum, non-selective herbicide which has been widely used for weed control. "( Glyphosate effects on the gene expression of the apical bud in soybean (Glycine max).
Guo, Y; Jiang, LX; Jin, LG; Qiu, LJ; Tao, B, 2013
)
3.28
"Glyphosate is a widely used herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) activity. "( Identification of regulated genes conferring resistance to high concentrations of glyphosate in a new strain of Enterobacter.
Fei, YY; Gai, JY; Zhao, TJ, 2013
)
2.06
"Glyphosate is a member of a large group of chemicals, phosphonic acids or phosphonates, which are characterized by a carbon-phosphorus bond."( Utilization of glyphosate as phosphate source: biochemistry and genetics of bacterial carbon-phosphorus lyase.
Hove-Jensen, B; Jochimsen, B; Zechel, DL, 2014
)
1.48
"Glyphosate is a broad-spectrum organophosphate (OP) herbicide, highly soluble in water, and when applied in terrestrial systems it penetrates into soil, eventually reaching the aquatic community and affecting nontarget organisms. "( Changes in ultrastructure and expression of steroidogenic factor-1 in ovaries of zebrafish Danio rerio exposed to glyphosate.
Ammar, D; Armiliato, N; Muller, YM; Nazari, EM; Nezzi, L; Straliotto, M, 2014
)
2.06
"Glyphosate is a widely applied broad-spectrum systemic herbicide that inhibits competitively the penultimate enzyme 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) from the shikimate pathway, thereby causing deleterious effects. "( A red and far-red light receptor mutation confers resistance to the herbicide glyphosate.
Bressan, RA; Gehring, C; Merzaban, JS; Narasimhan, ML; Sharkhuu, A; Weller, S, 2014
)
2.07
"Glyphosate is an agrochemical widely used to control weeds. "( Occurrence of glyphosate in water bodies derived from intensive agriculture in a tropical region of southern Mexico.
Bello-Mendoza, R; Castro, R; Rivero-Pérez, N; Ruiz-Toledo, J; Sánchez, D, 2014
)
2.21
"Glyphosate is an active substance of the most popular herbicides worldwide. "( Glyphosate affects the spontaneous motoric activity of intestine at very low doses - in vitro study.
Chłopecka, M; Dziekan, N; Karlik, W; Mendel, M, 2014
)
3.29
"Glyphosate (GLY) is a broad-spectrum herbicide used for weed control. "( Effects of field-realistic doses of glyphosate on honeybee appetitive behaviour.
Arenas, A; Farina, WM; Herbert, LT; Vázquez, DE, 2014
)
2.12
"Glyphosate is a systemic, non-selective herbicide widely used in agriculture worldwide. "( Effect of glyphosate on the sperm quality of zebrafish Danio rerio.
Corcini, CD; da Rosa, CE; da Silva, AC; Guazzelli, VG; Lopes, FM; Tavares, G; Varela Junior, AS, 2014
)
2.25
"Glyphosate is a broad-spectrum herbicide frequently used world widely in agricultural and non-agricultural areas to control unwanted plants. "( Immunological and histopathological responses of the kidney of common carp (Cyprinus carpio L.) sublethally exposed to glyphosate.
Bu, Y; Li, X; Ma, J, 2015
)
2.07
"Glyphosate is a non-selective herbicide that is effective against all types of weeds and has been used for many years."( Removal of glyphosate herbicide from water using biopolymer membranes.
Beppu, MM; Campos, EV; Carneiro, RT; da Silva, CM; de Moraes, MA; Fraceto, LF; Gomes Neto, RJ; Oliveira, JL; Taketa, TB, 2015
)
1.53
"Glyphosate is a broad spectrum herbicide widely used throughout the world, and it could be degraded by glycine oxidase (GO) through CN bond cleavage. "( Improvement of glycine oxidase by DNA shuffling, and site-saturation mutagenesis of F247 residue.
Kumar, A; Lin, Y; Liu, Z; Lu, Y; Wu, G; Yao, P; Zhan, T; Zhang, L, 2015
)
1.86
"Glyphosate is a herbicide that is widely applied to cereal crops in Egypt and is used in controlling a very broad spectrum of weeds."( RETRACTED: Glyphosate herbicide induces genotoxic effect and physiological disturbances in Bulinus truncatus snails.
Abd El-Atti, MS; Bakry, FA; Ismail, SM, 2015
)
1.53
"Glyphosate (GLY) is a herbicide that is widely used in agriculture for weed control. "( Effects of sublethal doses of glyphosate on honeybee navigation.
Balbuena, MS; Farina, WM; Greggers, U; Hahn, ML; Menzel, R; Tison, L, 2015
)
2.15
"Glyphosate is a commonly applied herbicide in coffee plantations. "( Analysis of glyphosate and aminomethylphosphonic acid in leaves from Coffea arabica using high performance liquid chromatography with quadrupole mass spectrometry detection.
Cedergreen, N; Christensen, JH; Masís-Mora, M; Rojas, EC; Schrübbers, LC; Valverde, BE, 2016
)
2.26
"As glyphosate is a broad spectrum herbicide extensively used in agriculture worldwide, identification of new aroA genes with high level of glyphosate tolerance is essential for the development and breeding of transgenic glyphosate-tolerant crops. "( A Novel Naturally Occurring Class I 5-Enolpyruvylshikimate-3-Phosphate Synthase from Janibacter sp. Confers High Glyphosate Tolerance to Rice.
Cui, Y; Lin, YJ; Liu, ZD; Yi, SY; Zhao, Y; Zhou, F, 2016
)
1.27
"Glyphosate is a non-selective and post-emergent herbicide that affects plant growth. "( Glyphosate-based herbicide exposure causes antioxidant defence responses in the fruit fly Drosophila melanogaster.
da Rosa, CE; de Aguiar, LM; Figueira, FH; Gottschalk, MS,
)
3.02
"Glyphosate is a globally popular herbicide to kill weeds and its wide applications may lead to accumulation in coastal oceans as a source of phosphorus (P) nutrient or growth inhibitor of phytoplankton. "( Differential Growth Responses of Marine Phytoplankton to Herbicide Glyphosate.
Li, L; Lin, S; Lin, X; Wang, C, 2016
)
2.11
"Glyphosate is a broad-spectrum herbicide used widely in agriculture, horticulture, private gardens, and public infrastructure, where it is applied to areas such as roadsides, railway tracks, and parks to control the growth of weeds. "( Glyphosate and aminomethylphosphonic acid chronic risk assessment for soil biota.
Levine, SL; Manson, PS; Mehrsheikh, A; Sutton, P; von Mérey, G, 2016
)
3.32
"Glyphosate is a herbicide used to control broad-leaved weeds. "( An assessment of dietary exposure to glyphosate using refined deterministic and probabilistic methods.
Harris, CA; Stephenson, CL, 2016
)
2.15
"Glyphosate is a broad spectrum herbicide used aggressively in agricultural practices as well as home garden care. "( Glyphosate induces cardiovascular toxicity in Danio rerio.
Anderson, A; Ochs, J; Roy, NM; Zambrzycka, E, 2016
)
3.32
"Glyphosate is a chelating agent that can form stable complexes with divalent metal ions including Cu(II)."( Behavioral responses of juvenile Daphnia magna after exposure to glyphosate and glyphosate-copper complexes.
Hansen, LR; Roslev, P, 2016
)
1.39
"Glyphosate is an important non-selective herbicide that is in common use worldwide. "( Investigating the mechanisms of glyphosate resistance in goosegrass (Eleusine indica (L.) Gaertn.) by RNA sequencing technology.
Chen, J; Huang, H; Huang, Z; Wang, X; Wei, S; Zhang, C, 2017
)
2.18
"Glyphosate (GLY) is a common herbicide used worldwide but its effect on ovarian function in mammals is unknown. "( Evidence for direct effects of glyphosate on ovarian function: glyphosate influences steroidogenesis and proliferation of bovine granulosa but not theca cells in vitro.
Albonico, M; Caloni, F; Cortinovis, C; Perego, MC; Schutz, LF; Spicer, LJ, 2017
)
2.18
"Glyphosate is an herbicide that is used worldwide with potential environmental risks to nontarget organisms. "( Treating Prey With Glyphosate Does Not Alter the Demographic Parameters and Predation of the Harmonia axyridis (Coleoptera: Coccinellidae).
Chi, H; Honek, A; Lukáš, J; Saska, P; Skuhrovec, J; Tuan, SJ; Vlach, M, 2017
)
2.23
"Glyphosate is a highly used active compound in agriculturally based pesticides. "( Evaluation of various glyphosate concentrations on DNA damage in human Raji cells and its impact on cytotoxicity.
Heaton, M; Meng, W; O'Neill, K; Peck, C; Robison, R; Townsend, M, 2017
)
2.21
"Glyphosate is a commonly used nonselective herbicide which inhibits plant growth through interference with the production of essential aromatic amino acids. "( [Dysphonia following glyphosate exposition].
Ptok, M, 2009
)
2.11
"Glyphosate is a herbicide widely used to kill weeds both in agricultural and non-agricultural landscapes. "( Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology.
Bernardi, MM; Furtado, PV; Oliveira, CA; Romano, MA; Romano, RM, 2010
)
2.04
"Glyphosate is a widely used broad spectrum herbicide, reported to induce various toxic effects in non-target species, but its carcinogenic potential is still unknown. "( Studies on glyphosate-induced carcinogenicity in mouse skin: a proteomic approach.
George, J; Mahmood, Z; Prasad, S; Shukla, Y, 2010
)
2.19
"Glyphosate is a broad spectrum herbicide which has been widely used for non-selective weed control in turfgrass management. "( Genome-wide profiling and analysis of Festuca arundinacea miRNAs and transcriptomes in response to foliar glyphosate application.
Bakar, M; Budak, H; Shearman, RC; Unver, T, 2010
)
2.02
"Glyphosate is a non-volatile herbicide that is relatively immobile in soil."( Degradation of 14C-glyphosate in compost amended soils.
Alexa, E; Bragea, M; Lazureanu, A; Negrea, M; Sumalan, R, 2009
)
1.4
"Glyphosate is a non-selective broad-spectrum herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS, also designated as AroA), a key enzyme in the aromatic amino acid biosynthesis pathway in microorganisms and plants. "( Novel AroA from Pseudomonas putida confers tobacco plant with high tolerance to glyphosate.
Chang, SH; Li, Y; Sun, YC; Tian, ZX; Wang, J; Wang, YP; Yan, HQ; Zhang, L, 2011
)
2.04
"Glyphosate is a non-selective, foliar-applied, systemic herbicide that kills weeds by inhibiting the synthesis of 5-enolpyruvylshikimate-3-phosphate synthase. "( Evaluation of the efficacy of glyphosate plus urea phosphate in the greenhouse and the field.
Cao, Y; He, S; Li, P; Ni, H; Qian, K; Tang, T, 2012
)
2.11
"Glyphosate is a herbicide that is liable to be used in the extensive cultivation of glyphosate-tolerant cultivars. "( Potential accumulative effect of the herbicide glyphosate on glyphosate-tolerant maize rhizobacterial communities over a three-year cultivation period.
Barriuso, J; Marín, S; Mellado, RP, 2011
)
2.07
"Glyphosate is a herbicide in common use, in both agricultural and residential settings. "( Estimating maternal and prenatal exposure to glyphosate in the community setting.
Callan, AC; Hinwood, AL; McQueen, H, 2012
)
2.08
"Glyphosate is an extensively used herbicide that has been shown to increase the risk of cancer."( Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells.
Berquand, A; Elie-Caille, C; Heu, C; Nicod, L, 2012
)
2.54
"Glyphosate is an herbicide used widely and increasingly since the early 1990s in production of many crops and in urban areas. "( Transport and attenuation of dissolved glyphosate and AMPA in a stormwater wetland.
Imfeld, G; Lefrancq, M; Maillard, E; Payraudeau, S, 2013
)
2.1
"Glyphosate (GPS) is a wildly-used pesticide throughout the world. "( Does glyphosate impact on Cu uptake by, and toxicity to, the earthworm Eisenia fetida?
Sun, RJ; Wang, YJ; Yu, YC; Zhang, HL; Zhou, CF; Zhou, DM; Zhu, XD, 2012
)
2.34
"Glyphosate is an effective antimetabolite that inhibits 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase in the shikimate pathway, thereby resulting in a shortage of the chorismate-derived essential aromatic amino acids."( Genome-wide transcriptional responses of Escherichia coli to glyphosate, a potent inhibitor of the shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase.
Chen, M; Li, L; Lin, M; Lu, W; Ping, S; Wang, J; Yan, Y; Zhang, W; Zhou, Z, 2013
)
1.35
"Glyphosate (GlySH) is a broad spectrum, nonselective herbicide, widely used in agriculture. "( Accidental chemical burns of oral mucosa by herbicide.
Deo, SP; Shetty, P,
)
1.57
"Glyphosate is a widely used non-selective herbicide. "( Leaching of pesticides through normal-tillage and low-tillage soil--a lysimeter study. II. Glyphosate.
Felding, G; Fomsgaard, IS; Spliid, NH, 2003
)
1.98
"Glyphosate is a nonselective herbicide used as a harvest aid in a variety of crops. "( Glyphosate applied preharvest induces shikimic acid accumulation in hard red spring wheat (Triticum aestivum).
Bresnahan, GA; Chakraborty, M; Howatt, KA; Manthey, FA, 2003
)
3.2
"Glyphosate is a non-selective broad-spectrum herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), a key enzyme in the aromatic amino acid biosynthetic pathway in microorganisms and plants. "( Expression of a bacterial aroA mutant, aroA-M1, encoding 5-enolpyruvylshikimate-3-phosphate synthase for the production of glyphosate-resistant tobacco plants.
Li, YF; Wang, HY; Xie, LX; Xu, P, 2003
)
1.97
"Glyphosate is a broad-spectrum herbicide that is one of the most frequently applied pesticides in the world. "( Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health Study.
Alavanja, MC; Blair, A; De Roos, AJ; Dosemeci, M; Hoppin, JA; Rusiecki, JA; Sandler, DP; Svec, M, 2005
)
2.08
"Glyphosate is a non-selective herbicide which acts by inhibiting 5-enolpyruvylshikimate-3-phosphate synthase. "( Expression of a wheat cytochrome P450 monooxygenase in yeast and its inhibition by glyphosate.
Ju, XL; Ren, TR; Wang, XJ; Xiang, WS, 2005
)
2
"Glyphosate is a commonly used nonselective herbicide that inhibits plant growth through interference with the production of essential aromatic amino acids. "( Oral bioavailability of glyphosate: studies using two intestinal cell lines.
Moore, MM; Pinto, LJ; Vasiluk, L, 2005
)
2.08
"Glyphosate is a non-selective, broad spectrum, post-emergent herbicide widely used in weed control. "( Aminomethylphosphonic acid and glyphosate adsorption onto goethite: a comparative study.
Barja, BC; Dos Santos Afonso, M, 2005
)
2.06
"Glyphosate is a post-emergence herbicide that acts on the synthesis of amino acids and other endogenous metabolites in plants. "( Effect of the herbicide glyphosate on liver lipoperoxidation in pregnant rats and their fetuses.
Beuret, CJ; Giménez, MS; Zirulnik, F,
)
1.88
"Glyphosate is a broad-spectrum herbicide, and its behaviour-as well as that of other herbicides-in soils is an important consideration for the overall environmental evaluation of genetically resistant crop introduction."( Glyphosate adsorption in soils compared to herbicides replaced with the introduction of glyphosate resistant crops.
Barriuso, E; Mamy, L, 2005
)
2.49
"Glyphosate is a broad-spectrum non-selective herbicide, used to eliminate unwanted weeds in agricultural and forest settings. "( [Cytotoxicity and genotoxicity of human cells exposed in vitro to glyphosate].
Cortés, AC; de Restrepo, HG; Monroy, CM; Sicard, DM, 2005
)
2.01
"Glyphosate is a broad-spectrum herbicide used for the control of weeds in glyphosate-resistant crops. "( Glyphosate inhibits rust diseases in glyphosate-resistant wheat and soybean.
Alibhai, MF; Baley, GJ; Bunkers, GJ; Clinton, WP; Feng, PC; Kidwell, KK; Paulitz, TC, 2005
)
3.21
"Glyphosate (GPS) is a non-selective, post-mergence herbicide that is widely used throughout the world. "( Effects of phosphate on the adsorption of glyphosate on three different types of Chinese soils.
Sun, RJ; Wang, YJ; Zhou, DM, 2005
)
2.04
"Glyphosate is a non-selective broad-spectrum herbicide that inhibits 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). "( Simultaneous substitution of Gly96 to Ala and Ala183 to Thr in 5-enolpyruvylshikimate-3-phosphate synthase gene of E. coli (k12) and transformation of rapeseed (Brassica napus L.) in order to make tolerance to glyphosate.
Afshari, A; Kahrizi, D; Moieni, A; Mousavi, A; Salmanian, AH, 2007
)
1.97
"Glyphosate is a widely used broad-spectrum weed control agent. "( Detection of cytogenetic and DNA damage in peripheral erythrocytes of goldfish (Carassius auratus) exposed to a glyphosate formulation using the micronucleus test and the comet assay.
Cavaş, T; Könen, S, 2007
)
1.99
"Glyphosate is a widely used broad-spectrum herbicide. "( The control of Asian rust by glyphosate in glyphosate-resistant soybeans.
Andrade, GC; Balbi, MC; Caldwell, P; Clark, C; Feng, PC, 2008
)
2.08
"Glyphosate tolerance is a dominant trait in modern biotech crops."( Characterization and plant expression of a glyphosate-tolerant enolpyruvylshikimate phosphate synthase.
Beilinson, V; Bryant, CT; Carozzi, NB; Carr, B; Chen, Z; Chun, BL; Deter, R; Duck, NB; Eberle, T; Guo, R; Hammer, PE; Hinson, TK; Koziel, MG; Moellenbeck, DJ; Peters, C; Samoylov, V; Schouten, LC; Shekita, A; Stauffer, ME; Vande Berg, BJ, 2008
)
2.05
"Glyphosate is a highly effective broad-spectrum herbicide, yet it is very toxicologically and environmentally safe."( Glyphosate: a once-in-a-century herbicide.
Duke, SO; Powles, SB, 2008
)
2.51
"Glyphosate is a broad-spectrum, non-selective herbicide and commonly used to eliminate weeds in agricultural and forest settings. "( [Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cells].
Martínez, A; Reyes, I; Reyes, N, 2007
)
2.07
"Glyphosate is a potent inhibitor of three enzymes of aromatic amino acid biosynthesis in this yeast."( Mode of action of glyphosate in Candida maltosa.
Birnbaum, D; Bode, R; Melo, C, 1984
)
1.32
"Glyphosate was found to be an uncompetitive inhibitor versus EPSP with Kii(app) = 54 +/- 2 microM.(ABSTRACT TRUNCATED AT 250 WORDS)"( Reevaluating glyphosate as a transition-state inhibitor of EPSP synthase: identification of an EPSP synthase.EPSP.glyphosate ternary complex.
Anderson, KS; Gruys, KJ; Johnson, KA; Sammons, RD; Sikorski, JA, 1995
)
1.38
"Glyphosate is a potent herbicide whereas its phosphonate monoester derivative, glyceryl glyphosate, is approximately 50-fold less active."( A phosphonate monoester hydrolase from Burkholderia caryophilli PG2982 is useful as a conditional lethal gene in plants.
Dotson, SB; Kishore, GM; Lanahan, MB; Smith, AG, 1996
)
1.02
"Glyphosate is a potent herbicide. "( Containment of herbicide resistance through genetic engineering of the chloroplast genome.
Daniell, H; Datta, R; Gray, S; Lee, SB; Varma, S, 1998
)
1.74
"Glyphosate is a herbicide that blocks the shikimic acid pathway. "( Glyphosate effects on phenolic metabolism of nodulated soybean (Glycine max L. merr.).
Becerril, JM; Garcia-Plazaola, JI; Hernandez, A, 1999
)
3.19
"Glyphosate is an organophosphorated nonselective agrochemical widely used in many countries including Argentina and acts after the sprout in a systemic way."( Effect of the herbicide glyphosate on enzymatic activity in pregnant rats and their fetuses.
Daruich, J; Gimenez, MS; Zirulnik, F, 2001
)
1.34
"Glyphosate is a widely used herbicide that inhibits the synthesis of aromatic amino acids via the shikimate acid pathway."( Glyphosate inhibits melanization of Cryptococcus neoformans and prolongs survival of mice after systemic infection.
Casadevall, A; Nosanchuk, JD; Ovalle, R, 2001
)
2.47
"Glyphosate is a widely-used broad-spectrum herbicide with little to no hazard to man or the environment. "( The biological activity of glyphosate to plants and animals: a literature review.
Oehme, FW; Smith, EA, 1992
)
2.02
"Glyphosate is a broad-spectrum postemergence translocated herbicide. "( Glyphosate skin binding, absorption, residual tissue distribution, and skin decontamination.
Maibach, HI; McMaster, J; Melendres, J; Sarason, R; Wester, RC, 1991
)
3.17

Effects

Glyphosate has a reputation of being nontoxic to animals and rapidly inactivated in soils. It shows low bioavailability following oral ingestion and low systemic toxicity following intravenous exposures.

Glyphosate has been described as an endocrine disruptor affecting the male reproductive system. The molecular basis of its toxicity remains to be clarified. Glyphosate residues have been detected in surface and groundwater, in food, and in human blood and urine.

ExcerptReferenceRelevance
"Glyphosate has a high sorption affinity, yet it can be detected occasionally in groundwater."(
Ditterich, F; Haderlein, S; Huhn, C; Kandeler, E; Martin-Laurent, F; Poll, C; Schlögl, J; Wimmer, B; Wirsching, J, 2022
)
1.44
"Glyphosate has an amino acid-like structure that is highly polar and shows low bioavailability following oral ingestion and low systemic toxicity following intravenous exposures."( The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial tissues.
Cai, J; Donovan, MD; He, S; Huang, J; Li, G; Si, L; Wang, Z; Xu, J, 2016
)
1.4
"Glyphosate has a reputation of being nontoxic to animals and rapidly inactivated in soils."( Glyphosate in northern ecosystems.
Helander, M; Saikkonen, K; Saloniemi, I, 2012
)
2.54
"Glyphosate has antimicrobial and mineral chelating properties and we investigated whether there is an association between feed residues of glyphosate on the one side and broiler breeder egg laying percent and egg hatchability on the other side."( Impact of feed glyphosate residues on broiler breeder egg production and egg hatchability.
Foldager, L; Nørskov, NP; Sørensen, MT; Winters, JFM, 2021
)
1.7
"Glyphosate has been detected in urine, blood and maternal milk and has been found to induce the generation of reactive oxygen species (ROS) and several cytotoxic and genotoxic effects in vitro and in animal models directly or indirectly through its metabolite, aminomethylphosphonic acid (AMPA)."( Pleiotropic Outcomes of Glyphosate Exposure: From Organ Damage to Effects on Inflammation, Cancer, Reproduction and Development.
Marino, M; Meccariello, R; Mele, E; Nori, SL; Santoro, A; Viggiano, A, 2021
)
1.65
"Glyphosate has a high sorption affinity, yet it can be detected occasionally in groundwater."(
Ditterich, F; Haderlein, S; Huhn, C; Kandeler, E; Martin-Laurent, F; Poll, C; Schlögl, J; Wimmer, B; Wirsching, J, 2022
)
1.44
"Glyphosate has been shown to cross the blood-brain barrier in in vitro models, but has yet to be verified in vivo."( Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders.
Huentelman, MJ; Pathak, KV; Piras, IS; Pirrotte, P; Sharma, R; Velazquez, R; White, J; Winslow, W; Winstone, JK, 2022
)
2.89
"Glyphosate has been the most widely used herbicide for decades providing a unique tool, alone or in mixtures, to control weeds on citrus in Veracruz. "( Reduced Glyphosate Movement and Mutation of the
Barro, F; De Prado, R; Domínguez-Valenzuela, JA; López-Valencia, G; Palma-Bautista, C; Vázquez-Garcia, JG, 2023
)
2.79
"Glyphosate has become the most widely used herbicide in the world. "( Identification and integrated analysis of glyphosate stress-responsive microRNAs, lncRNAs, and mRNAs in rice using genome-wide high-throughput sequencing.
Chu, Q; Lu, Y; Ye, J; Ye, S; Yu, F; Zhai, R; Zhang, X; Zhu, G, 2020
)
2.27
"Glyphosate has excellent properties of fast sorption in soil, biodegradation and less toxicity to nontarget organisms."( Controversies over human health and ecological impacts of glyphosate: Is it to be banned in modern agriculture?
Annamalai, P; Asaduzzaman, M; Dharmarajan, R; Meftaul, IM; Megharaj, M; Parven, A; Venkateswarlu, K, 2020
)
1.52
"Glyphosate (PMG) has been the most widely used herbicide in the world, and its environmental mobility and fate are mainly controlled by interactions with mineral surfaces. "( Glyphosate adsorption onto kaolinite and kaolinite-humic acid composites: Experimental and molecular dynamics studies.
Fein, JB; Guo, F; Huang, Q; Rong, X; Wang, Y; Xu, J; Yu, Q; Zhou, M, 2021
)
3.51
"Glyphosate has been used intensively on wild poinsettia (Euphorbia heterophylla L.) populations for at least 20 years in GR crops within South America."( Evolution of EPSPS double mutation imparting glyphosate resistance in wild poinsettia (Euphorbia heterophylla L.).
Adegas, FS; Dayan, FE; Gaines, TA; Leal, JF; Mendes, RR; Morran, S; Oliveira, RS; Souza, AS; Takano, HK, 2020
)
1.54
"Glyphosate has prominent role in shikimic acid pathway, decreasing lignin synthesis resulting in improved growth and productivity of several crops."( Hormesis in plants: Physiological and biochemical responses.
Fernandes, GC; Jalal, A; Mariano, GG; Oliveira Junior, JC; Reis, ARD; Ribeiro, JS; Trindade, VDR, 2021
)
1.34
"Glyphosate has been banned in some herbicidal formulations. "( Toxic compounds in herbicides without glyphosate.
Jungers, G; Seralini, GE, 2020
)
2.27
"Glyphosate has become the best-selling herbicide used in agriculture, horticulture, silviculture, and urban environments. "( Glyphosate-Modulated Biosynthesis Driving Plant Defense and Species Interactions.
Fuchs, B; Helander, M; Saikkonen, K, 2021
)
3.51
"Glyphosate has been frequently detected in water environments because of the wide use for controlling weed in farm lands and urban areas. "( Glyphosate escalates horizontal transfer of conjugative plasmid harboring antibiotic resistance genes.
Liu, J; Wang, L; Zhai, Z; Zhang, H, 2021
)
3.51
"Glyphosate has been widely and extensively used for weed control because of its excellent herbicidal profile and low costs. "( Effective removal of the herbicide glyphosate by the kelp Saccharina japonica female gametophytes from saline waters and its mechanism elucidation.
Gao, J; Liu, S; Shen, L; Tang, X, 2021
)
2.34
"Glyphosate has been used for weed control in South China in various situations for four decades, and most Eleusine indica populations are suspected to have evolved resistance to glyphosate. "( Evolution of multiple target-site resistance mechanisms in individual plants of glyphosate-resistant Eleusine indica from China.
Guo, WL; Tian, XS; Yu, CJ; Yu, Q; Zhang, C; Zhang, TJ, 2021
)
2.29
"Glyphosate degradation has been extensively examined; however, only a few detailed computational studies have been performed on the topic so far. "( The fate of a hazardous herbicide: a DFT-based
Ingersoll, DW; Purgel, M; Sadatsharifi, M, 2021
)
2.06
"Glyphosate has become the most commonly used herbicide worldwide and is reputedly environmentally benign, nontoxic, and safe for use near wildlife and humans. "( The rise of glyphosate and new opportunities for biosentinel early-warning studies.
Kissane, Z; Shephard, JM, 2017
)
2.28
"Glyphosate has been used for more than 15 years for weed management in citrus groves in the Gulf of Mexico, at up to 3-4 applications per year. "( Pro-106-Ser mutation and EPSPS overexpression acting together simultaneously in glyphosate-resistant goosegrass (Eleusine indica).
Alcántara-de la Cruz, R; Cruz-Hipolito, HE; De Prado, R; Domínguez-Valenzuela, JA; Fernández-Moreno, PT; Gherekhloo, J; Sánchez-González, E, 2017
)
2.12
"Glyphosate has long been used to manage invasive hybrid cattails in wetlands in North America, but hybrid cattail expansions continue to occur."( Glyphosate (Ab)sorption by Shoots and Rhizomes of Native versus Hybrid Cattail (Typha).
de Jager, P; Farenhorst, A; Grosshans, R; Munira, S; Sutton, NB; Zheng, T, 2017
)
2.62
"Glyphosate has never been considered acutely toxic; however, in 2015 the European Food Safety Authority (EFSA) proposed an acute reference dose (ARfD)."( An assessment of the acute dietary exposure to glyphosate using deterministic and probabilistic methods.
Clarke, R; Harris, CA; Stephenson, CL, 2018
)
1.46
"Glyphosate has been the most widely used herbicide worldwide over the last three decades, raising increasing concerns for its potential impacts on environmental and human health. "( Ecotoxicological effects of the herbicide glyphosate in non-target aquatic species: Transcriptional responses in the mussel Mytilus galloprovincialis.
Bargelloni, L; Bogialli, S; Dalla Rovere, G; Ferraresso, S; Marin, MG; Matozzo, V; Milan, M; Pastore, P; Patarnello, T; Smits, M, 2018
)
2.19
"Glyphosate and dicamba have been used for decades to control K."( Reduced Translocation of Glyphosate and Dicamba in Combination Contributes to Poor Control of Kochia scoparia: Evidence of Herbicide Antagonism.
Bloedow, N; Jugulam, M; Ou, J; Stahlman, PW; Thompson, CR, 2018
)
1.51
"Glyphosate has emerged as the most widespread herbicide to control annual and perennial weeds. "( Recent advances in glyphosate biodegradation.
Chen, S; Fan, X; Feng, Y; Zhan, H, 2018
)
2.25
"Glyphosate has recently received much public attention following its 'Group 2A - probably carcinogenic to humans' classification from the International Agency for Research on Cancer. "( Characterising glyphosate exposures among amenity horticulturists using multiple spot urine samples.
Basinas, I; Coggins, MA; Connolly, A; Galea, KS; Jones, K; Kenny, L; McGowan, P, 2018
)
2.28
"Glyphosate has been suggested to be an endocrine disrupting chemical capable of disrupting male reproduction. "( Exposure to a glyphosate-based herbicide formulation, but not glyphosate alone, has only minor effects on adult rat testis.
Bahl, MI; Boberg, J; Johansson, HKL; Nielsen, LN; Schwartz, CL; Svingen, T; Vinggaard, AM, 2018
)
2.28
"Glyphosate has been considered safe to animals as it mainly targets physiological pathways in plants."( Effects of a glyphosate-based herbicide on survival and oxidative status of a non-target herbivore, the Colorado potato beetle (Leptinotarsa decemlineata).
Helander, M; Lehmann, P; Lindström, L; Margus, A; Rainio, MJ, 2019
)
1.6
"As glyphosate has effects at the ADI level, our data suggest that the current ADI for glyphosate could be overestimated."( Perinatal Exposure to Glyphosate and a Glyphosate-Based Herbicide Affect Spermatogenesis in Mice.
Derian, L; Gely-Pernot, A; Jégou, B; Kernanec, PY; Kervarrec, C; Pham, TH; Smagulova, F, 2019
)
1.34
"Glyphosate residues have been detected in surface and groundwater, in food, and in human blood and urine."( Histopathological and ultrastructural indices for the assessment of glyphosate-based herbicide cytotoxicity in decapod crustacean hepatopancreas.
de Melo, MS; Dos Santos, TPG; Jaramillo, M; Nazari, EM; Nezzi, L; Rauh Muller, YM, 2019
)
1.47
"Glyphosate has been described as an endocrine disruptor affecting the male reproductive system; however, the molecular basis of its toxicity remains to be clarified."( Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.
Benedetti Parisotto, E; Cattani, D; de Liz Oliveira Cavalli, VL; Heinz Rieg, CE; Mena Barreto Silva, FR; Pessoa-Pureur, R; Pierozan, P; Wilhelm Filho, D; Zamoner, A; Zanatta, L, 2013
)
1.11
"Glyphosate use has increased over the last decades for the control of invasive plant species in wetland ecosystems. "( Effects of sub-lethal glyphosate concentrations on growth and photosynthetic performance of non-target species Bolboschoenus maritimus.
Mateos-Naranjo, E; Perez-Martin, A, 2013
)
2.15
"Glyphosate surfactant has recently been used with increasing frequency in suicide attempts, so clinical toxicologists occasionally encounter cases of severe systemic toxicity."( Heart rate-corrected QT interval predicts mortality in glyphosate-surfactant herbicide-poisoned patients.
Cho, KW; Hong, CK; Hwang, SY; Kim, YH; Kim, YW; Lee, JH; Park, YH, 2014
)
1.37
"Glyphosate has been used widely in the south of China."( Mutations and amplification of EPSPS gene confer resistance to glyphosate in goosegrass (Eleusine indica).
Chen, J; Huang, H; Huang, Z; Wang, X; Wei, S; Zhang, C, 2015
)
1.38
"Glyphosate has an amino acid-like structure that is highly polar and shows low bioavailability following oral ingestion and low systemic toxicity following intravenous exposures."( The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial tissues.
Cai, J; Donovan, MD; He, S; Huang, J; Li, G; Si, L; Wang, Z; Xu, J, 2016
)
1.4
"Glyphosate has been used extensively for weed control in agriculture in many countries. "( Physiological effects of the herbicide glyphosate on the cyanobacterium Microcystis aeruginosa.
Du, Y; Hu, X; Liu, C; Qiu, Z; Wu, L; Ye, J; Zhou, Y, 2016
)
2.15
"Glyphosate has been the most widely used herbicide during the past three decades. "( Glyphosate: environmental contamination, toxicity and potential risks to human health via food contamination.
Bai, SH; Ogbourne, SM, 2016
)
3.32
"Glyphosate has been shown to affect the development of plant disease in several ways. "( How glyphosate affects plant disease development: it is more than enhanced susceptibility.
Hammerschmidt, R, 2018
)
2.48
"Glyphosate has already been approved under this directive."( Weed control in glyphosate-tolerant maize in Europe.
Dewar, AM, 2009
)
1.42
"Glyphosate neurotoxicity has been discussed in the literature therefore, the dysphonia observed here may have been due to an intermittent neuropraxia of the laryngeal nerve."( [Dysphonia following glyphosate exposition].
Ptok, M, 2009
)
1.39
"Glyphosate has been shown to induce in vitro cutaneous cytotoxic effects, concomitant with oxidative disorders."( Morphological damages of a glyphosate-treated human keratinocyte cell line revealed by a micro- to nanoscale microscopic investigation.
Elie-Caille, C; Guyon, C; Heu, C; Nicod, L, 2010
)
1.38
"Glyphosate has been detected in a range of surface waters but this is the first study to monitor its fate in prairie wetlands situated in agricultural fields."( Dissipation of glyphosate and aminomethylphosphonic acid in water and sediment of two Canadian prairie wetlands.
Badiou, PH; Cessna, AJ; Degenhardt, D; Farenhorst, A; Humphries, D; Messing, P; Pennock, DJ; Raina, R, 2012
)
1.45
"Glyphosate has a reputation of being nontoxic to animals and rapidly inactivated in soils."( Glyphosate in northern ecosystems.
Helander, M; Saikkonen, K; Saloniemi, I, 2012
)
2.54
"Glyphosate has worked extremely well in controlling weeds in glyphosate-resistant crops for more than a decade, but some key weeds have evolved resistance, and using glyphosate alone has proved unsustainable."( The benefits of herbicide-resistant crops.
Green, JM, 2012
)
1.1
"Glyphosate has been used globally as a safe herbicide for weed control. "( Novel AroA with high tolerance to glyphosate, encoded by a gene of Pseudomonas putida 4G-1 isolated from an extremely polluted environment in China.
Chen, YC; Dowling, DN; Gilmartin, N; Li, FM; Lin, M; Sun, YC; Tian, ZX; Wang, XY; Wang, YP; Xiao, ZL; Zhang, J, 2005
)
2.05
"Glyphosate has performed long and well, but now some weed communities are shifting to populations that survive glyphosate, and growers need new weed management technologies to augment glyphosate performance in glyphosate-resistant crops. "( New multiple-herbicide crop resistance and formulation technology to augment the utility of glyphosate.
Forney, DR; Green, JM; Hazel, CB; Pugh, LM, 2008
)
2.01
"Glyphosate resistance has been confirmed in 58 populations of Lolium rigidum (Gaud.), a major weed of crops in southern Australia. "( A risk calculator for glyphosate resistance in Lolium rigidum (Gaud.).
Dill, GM; Hudson, D; Pratley, JE; Stanton, RA, 2008
)
2.1
"Glyphosate has broad spectrum herbicidal activity against a wide range of annual and perennial weeds. "( The herbicide glyphosate.
Barry, G; Kishore, G; Malik, J, 1989
)
2.08

Actions

Glyphosate did not cause reduction in chlorophyll content and shoot fresh weight in GR canola, unlike GR soybean. Glyphosate can generate positive effects on turfgrass maintenance as a form of growth control by decreasing the expenses associated with mowing.

ExcerptReferenceRelevance
"Glyphosate can cause tissue damage such as liver and kidney in mammals. "( Tannin alleviates glyphosate exposure-induced apoptosis, necrosis and immune dysfunction in hepatic L8824 cell line by inhibiting ROS/PTEN/PI3K/AKT pathway.
Chen, L; Qi, M; Tao, D; Xu, S; Yu, F; Zhang, L, 2023
)
2.69
"Glyphosate can generate positive effects on turfgrass maintenance as a form of growth control by decreasing the expenses associated with mowing. "( Growth regulation of bermudagrass (
Carbonari, CA; Dadazio, TS; Dias, RC; Macedo, GC; Silva, PV; Tropaldi, L; Velini, ED, 2021
)
2.06
"Glyphosate at 840 (lower label limit) or 1260 (upper label limit) g ae/ha was applied twice at 3 and 6 WAP to transgenic corn."( Glyphosate effect on shikimate, nitrate reductase activity, yield, and seed composition in corn.
Bellaloui, N; Reddy, KN; Zablotowicz, RM, 2010
)
2.52
"Glyphosate did not cause reduction in chlorophyll content and shoot fresh weight in GR canola, unlike GR soybean."( Glyphosate-resistant and -susceptible soybean (Glycine max) and canola (Brassica napus) dose response and metabolism relationships with glyphosate.
Duke, SO; Nandula, VK; Poston, DH; Reddy, KN; Rimando, AM, 2007
)
2.5
"Glyphosate changed the flower symmetry from the actinomorphic type to the zygomorphic type."( Nitrogen metabolism and flower symmetry of petunia corollas treated with glyphosate.
Kimura, Y; Shimada, A,
)
1.08
"Glyphosate did not increase beta-oxidation."( Enhanced peroxisomal beta-oxidation of fatty acids and glutathione metabolism in rats exposed to phenoxyacetic acids.
Ahotupa, M; Hämäläinen, H; Heinonen, T; Hietanen, E; Kunnas, T; Linnainmaa, K; Mäntylä, E; Vainio, H, 1985
)
0.99

Treatment

Glyphosate treatments disrupted microbial taxonomic composition. Some bacteria seem to be sensitive to this environmental pollutant. Glyphosate treatment reduced leaf trichome density but had no effect on the other plant traits considered.

ExcerptReferenceRelevance
"Glyphosate treatments disrupted microbial taxonomic composition and some bacteria seem to be sensitive to this environmental pollutant."( Glyphosate-based herbicide exposure: effects on gill microbiota of rainbow trout (Oncorhynchus mykiss) and the aquatic bacterial ecosystem.
Almeras, F; Bellec, L; Cambon-Bonavita, MA; Danion, M; Durand, L; Le Du-Carré, J; Morin, T, 2022
)
2.89
"Glyphosate treatment reduced leaf trichome density but had no effect on the other plant traits considered."( Glyphosate residues in soil can modify plant resistance to herbivores through changes in leaf quality.
Helander, M; Kalske, A; Ramula, S; Saikkonen, K, 2022
)
2.89
"Glyphosate treatment of these glyphosate-resistant TIPS plants showed an increase in growth relative to those without glyphosate."( Challenging glyphosate resistance EPSPS P106S and TIPS mutations with soybean competition and glyphosate: implications for management.
Barroso, AAM; da Costa Aguiar Alves, PL; Han, H; Michelon, TB; Powles, SB; Vila-Aiub, MM; Yu, Q, 2022
)
1.82
"Glyphosate-treated assemblages were classified correctly; a subsetting approach identified the taxa primarily responsible for this, permitting the reduction of input features."( An artificial neural network and Random Forest identify glyphosate-impacted brackish communities based on 16S rRNA amplicon MiSeq read counts.
Janßen, R; Labrenz, M; von Lukas, U; Zabel, J, 2019
)
1.48
"Glyphosate and MON 52276 treatment resulted in ceca accumulation of shikimic acid and 3-dehydroshikimic acid, suggesting inhibition of 5-enolpyruvylshikimate-3-phosphate synthase of the shikimate pathway in the gut microbiome. "( Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats.
Amiel, C; Antoniou, MN; Belpoggi, F; Caldwell, A; Ducarmon, QR; Falcioni, L; Halket, J; Mandrioli, D; Mazzacuva, F; Mesnage, R; Panoff, JM; Teixeira, M; Zwittink, RD, 2021
)
2.3
"Glyphosate treatment significantly reduced the abundance and gene copy number of Staphylococcus and increased the abundance and gene copy number of Enterobacter."( Glyphosate exposure disturbs the bacterial endosymbiont community and reduces body weight of the predatory ladybird beetle Harmonia axyridis (Coleoptera: Coccinellidae).
Cui, J; Gao, X; Hu, F; Ji, J; Li, D; Luo, J; Niu, L; Wang, L; Wu, C; Zhang, K; Zhang, S; Zhu, X, 2021
)
2.79
"Glyphosate-treated rats (35, 75, 150 and 800mg/kg bw, 6 days), had no visible injury, i.e., no clinical signs of dysfunction were observed."( Neurotransmitter changes in rat brain regions following glyphosate exposure.
Anadón, A; Ares, I; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Rodríguez, JL, 2018
)
1.45
"Glyphosate treatment increased shikimate abundance in UABs 7 d after treatment; however, the abundance of shikimate gradually decreased as UABs transitioned through endo- and ecodormancy."( Foliar Glyphosate Treatment Alters Transcript and Hormone Profiles in Crown Buds of Leafy Spurge and Induces Dwarfed and Bushy Phenotypes throughout its Perennial Lifecycle.
Anderson, JV; Chao, WS; Doğramaci, M; Foley, ME; Hernandez, AG; Horvath, DP; Mikel, MA, 2017
)
1.63
"Glyphosate-treated C."( Molecular basis of natural tolerance to glyphosate in Convolvulus arvensis.
Huang, H; Huang, Z; Jiang, C; Liu, Y; Wei, S; Zhang, C, 2019
)
1.5
"Glyphosate-treated wild-type mice developed benign monoclonal gammopathy with increased serum IgG, anemia, and plasma cell presence in the spleen and bone marrow."( Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice.
Deng, Q; Gong, Z; Hu, H; Li, Y; Liu, M; Lu, Z; Ma, X; Wang, L; Xu-Monette, ZY; Young, KH; Zhang, S, 2019
)
2.68
"Glyphosate treatment did not lead to a huge increase of shikimate contents of tobacco leaves in transgenic plants overexpressing two genes, whereas significant increase of shikimate contents in transgenic plants containing only a single gene was observed."( Transgenic tobacco simultaneously overexpressing glyphosate N-acetyltransferase and 5-enolpyruvylshikimate-3-phosphate synthase are more resistant to glyphosate than those containing one gene.
Cao, G; Chen, R; Liu, Y; Lu, W; Ren, Y; Wang, G; Wang, J; Zhang, S, 2015
)
1.39
"Glyphosate-treated lilyturf plants accumulated little shikimic acid but had significantly higher levels of EPSPS mRNA than initially expressed in the control."( Multiple mechanism confers natural tolerance of three lilyturf species to glyphosate.
Chen, S; Mao, C; Qiang, S; Valverde, BE; Xie, H, 2016
)
1.39
"Glyphosate treatment caused the accumulation of shikimic and quinic acids (not detected in untreated samples) in R and NR calluses (with higher levels found in R tissues) and also decreased the FA/diFA ratio in cell wall phenolics, polyamine and amino acid levels, and increased sugar concentrations in the R L2 tissues, indicating a metabolic shift of R callus to NR tissues."( Metabolic effects of glyphosate change the capacity of maize culture to regenerate plants.
Duncan, D; Lozovaya, V; Lygin, A; Ulanov, A; Widholm, J, 2009
)
1.39
"To glyphosate applied treatments, a part of active agent comes in contact with soil surface, adsorbing to soil compounds, while another part remains in soil solution."( Researches regarding extractable glyphosate residues from different soils.
Alda, S; Alexa, E; Iordanescu, O; Lazureanu, A; Negrea, M, 2008
)
1.14
"In glyphosate drift-treated mesocosms, Brassica remained the dominant genus and the incidence of the CP4 EPSPS transgene increased in the community."( Changes in constructed Brassica communities treated with glyphosate drift.
Colasanti, R; King, G; Lee, EH; Londo, JP; Smith, BM; Waschmann, RS; Watrud, LS, 2011
)
1.13
"Glyphosate-treated plants showed impaired carbon metabolism with an accumulation of carbohydrates in the leaves and roots."( Impairment of carbon metabolism induced by the herbicide glyphosate.
Orcaray, L; Royuela, M; Zabalza, A; Zulet, A, 2012
)
1.35
"The glyphosate treatment during the three-year period of seasonal cultivation in two different fields did not seem to significantly change the maize rhizobacterial communities when compared to those of the untreated soil. "( Potential accumulative effect of the herbicide glyphosate on glyphosate-tolerant maize rhizobacterial communities over a three-year cultivation period.
Barriuso, J; Marín, S; Mellado, RP, 2011
)
1.18
"Late glyphosate and hoeing treatments resulted in cumulative dispersal statistically similar to or greater than from control plots."( Management of winter weeds affects Frankliniella fusca (Thysanoptera: Thripidae) dispersal.
Beaudoin, AL; Kennedy, GG, 2012
)
0.83
"Glyphosate treatments have the potential to affect relationships between the GR crop, plant pathogens, plant pests and symbiotic micro-organisms, although management practices can also have a large impact."( Technical performance of some commercial glyphosate-resistant crops.
Pline-Srnic, W, 2005
)
1.32
"All glyphosate treatments decreased nitrogenase activity rapidly (24 h) after application, even at the lowest and sublethal dose used (1.25 mM)."( New insights on glyphosate mode of action in nodular metabolism: Role of shikimate accumulation.
Becerril, JM; De Felipe, MR; de María, N; Fernandez-Pascual, M; García-Plazaola, JI; Hernandez, A, 2006
)
1.16
"Glyphosate treatment induced the accumulation of high levels of indole-3-acetic acid in GRC anthers."( Glyphosate-induced anther indehiscence in cotton is partially temperature dependent and involves cytoskeleton and secondary wall modifications and auxin accumulation.
Abu-Abied, M; Belausov, E; Madmony, A; Riov, J; Rubin, B; Sadot, E; Yasuor, H, 2006
)
2.5
"Treated glyphosate-sensitive plants showed an increase in shikimate, superoxide and H"( The moderate oxidative stress induced by glyphosate is not detected in Amaranthus palmeri plants overexpressing EPSPS.
Barco-Antoñanzas, M; Eceiza, MV; Gil-Monreal, M; Royuela, M; Zabalza, A, 2022
)
1.39
"Post-treatment of glyphosate-treated samples with distilled water allowed a partial recovery of the genotoxic effect of glyphosate, and some of the Psychotria extracts also did so."( Post-treatment with plant extracts used in Brazilian folk medicine caused a partial reversal of the antiproliferative effect of glyphosate in the Allium cepa test.
Frescura, VD; Kuhn, AW; Laughinghouse, HD; Paranhos, JT; Tedesco, SB, 2013
)
0.92
"When treated with glyphosate, susceptible (S) plants accumulated 4- to 6-fold more shikimic acid than resistant (R) plants."( Distinct non-target site mechanisms endow resistance to glyphosate, ACCase and ALS-inhibiting herbicides in multiple herbicide-resistant Lolium rigidum.
Abdallah, I; Han, H; Owen, M; Powles, S; Yu, Q, 2009
)
0.92

Toxicity

Both technical grade glyphosate and Roundup formulation were toxic to human peripheral blood mononuclear cells. Study is to investigate the potentially toxic effects of glyphosate on scallops.

ExcerptReferenceRelevance
" The use of protein-free medium considerably increased the sensitivity of sperm cells from rabbit and human to the toxic effects of the pesticide."( A sensitive sperm-motility test for the assessment of cytotoxic effect of pesticides.
Bertheussen, K; Helmi, S; Ibrahim, HZ; Salem, MH; Seehy, MA; Yousef, MI, 1996
)
0.29
" Also IC50 values of these pesticides were compared with LD50 values obtained from the literature."( A new sensitive cell culture test for the assessment of pesticide toxicity.
Bertheussen, K; Figenschau, Y; Yousef, MI, 1997
)
0.3
" moorei was slightly less toxic than Roundup(R) with 48-h LC50 values ranging between 27."( The toxicity of glyphosate and several glyphosate formulations to four species of southwestern Australian frogs.
Bidwell, JR; Mann, RM, 1999
)
0.65
" Likewise there were no adverse effects in reproductive tissues from animals treated with glyphosate, AMPA, or POEA in chronic and/or subchronic studies."( Safety evaluation and risk assessment of the herbicide Roundup and its active ingredient, glyphosate, for humans.
Kroes, R; Munro, IC; Williams, GM, 2000
)
0.75
" The results of the studies demonstrate that Roundup Ready soybeans are as safe as traditional soybeans with respect to food and feed safety."( Current methods for assessing safety of genetically modified crops as exemplified by data on Roundup Ready soybeans.
Fuchs, RL; Nair, RS; Schuette, SA,
)
0.13
" This study complements extensive agronomic, compositional and farm animal feeding studies with Roundup Ready corn grain, confirming it is as safe and nutritious as existing commercial corn hybrids."( Results of a 13 week safety assurance study with rats fed grain from glyphosate tolerant corn.
Dudek, R; Hammond, B; Lemen, J; Nemeth, M, 2004
)
0.56
" From the porewater toxicity tests, Roundup Biactive (340 mg kg(-1)) and Roundup (244 mg kg(-1)) were similarly toxic in the sediment tests at 0% organic carbon, indicating that the surfactants in Roundup were considerably more adsorptive than those in Roundup Biactive to the sediment of the same organic carbon."( Comparative toxicity of glyphosate-based herbicides: aqueous and sediment porewater exposures.
Chu, LM; Tsui, MT, 2004
)
0.63
"05) reductions in algal growth compared to the controls, although the 30-microg/L clopyralid or 10-microg/L glyphosate treatments did not exhibit any toxic effects."( Toxicity of herbicides in highway runoff.
Deanovic, L; Fong, S; Huang, X; Young, TM, 2005
)
0.54
" Carelessness in handling glyphosate or failure to follow label directions may produce adverse effects."( Toxicity of glyphosate as Glypro and LI700 to red-eared slider (trachemys scripta elegans) embryos and early hatchlings.
Bickham, J; Doelling-Brown, P; Matson, C; Sparling, DW, 2006
)
1.01
" The results showed that glyphosate-Roundup did not induce maternal toxicity but induced adverse reproductive effects on male offspring rats: a decrease in sperm number per epididymis tail and in daily sperm production during adulthood, an increase in the percentage of abnormal sperms and a dose-related decrease in the serum testosterone level at puberty, and signs of individual spermatid degeneration during both periods."( Pre- and postnatal toxicity of the commercial glyphosate formulation in Wistar rats.
Andrade, AJ; Dallegrave, E; Dalsenter, PR; Langeloh, A; Mantese, FD; Oliveira, RT, 2007
)
0.9
" Studies evaluating glyphosate toxicity in animals and environment show that commercial formulations of glyphosate are more toxic than the active component itself."( [Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cells].
Martínez, A; Reyes, I; Reyes, N, 2007
)
0.95
"Both technical grade glyphosate and Roundup formulation were toxic to human peripheral blood mononuclear cells."( [Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cells].
Martínez, A; Reyes, I; Reyes, N, 2007
)
0.94
"This in vitro study confirmed the toxic effects on human cells by glyphosate and its commercial preparations."( [Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cells].
Martínez, A; Reyes, I; Reyes, N, 2007
)
0.86
" In fact, although pesticides were not detected in elutriates, high levels of un-ionized ammonia were recorded, which is considered highly toxic to aquatic life."( A whole sample toxicity assessment to evaluate the sub-lethal toxicity of water and sediment elutriates from a lake exposed to diffuse pollution.
Abrantes, N; de Figueiredo, DR; Gonçalves, F; Marques, CR; Pereira, MJ; Pereira, R, 2009
)
0.35
" Analysis of morphological, hematological, biochemical parameters and system (sensitive) biomarkers has not confirmed any toxic effect of maize event MON 88017."( [Medical and biological safety assessment of genetically modified maize event MON 88017. Report 1. Toxicologo-hygienic examinations].
Aksiuk, IN; Avren'eva, LI; Chernysheva, ON; Gapparov, MM; Guseva, GV; kravchenko, LV; L'vova, LS; Saprykin, VP; Tutel'ian, VA; Tyshko, NV, 2008
)
0.35
" Both herbicides were innocuous to all test organisms at environmentally realistic concentrations, except for Stam and Propanil (highly toxic for Pseudokirchneriella; moderately toxic to Daphnia)."( Toxicity evaluation of three pesticides on non-target aquatic and soil organisms: commercial formulation versus active ingredient.
Antunes, SC; Castro, BB; Gonçalves, AM; Gonçalves, F; Marques, CR; Pereira, JL; Pereira, R, 2009
)
0.35
" The 2mEPSPS enzyme does not possess any of the properties associated with known toxins or allergens, including a lack of amino acid sequence similarity to known toxins and allergens, a rapid degradation in simulated gastric and intestinal fluids, and no adverse effects in mice after intravenous or oral administration (at 10 or 2000 mg/kg body weight, respectively)."( Safety evaluation of the double mutant 5-enol pyruvylshikimate-3-phosphate synthase (2mEPSPS) from maize that confers tolerance to glyphosate herbicide in transgenic plants.
Bates, EE; Currier, T; Ferullo, JM; Freyssinet, M; Hendrickx, K; Herouet-Guicheney, C; Martone, A; Rouan, D; Rouquié, D; Zhou, J, 2009
)
0.56
" However, direct adverse effects of pesticides on embryos and free-living stages of trematodes have not been thoroughly explored, despite the potential for these effects to reduce amphibian trematode infections."( Lack of pesticide toxicity to Echinostoma trivolvis eggs and miracidia.
Raffel, TR; Rohr, JR; Sheingold, JL, 2009
)
0.35
" Notably, in all the cases except for Synechocystis aquatilis Sauvageau, isopropylamine alone was indicated as more toxic than glyphosate."( The toxicity of Roundup® 360 SL formulation and its main constituents: glyphosate and isopropylamine towards non-target water photoautotrophs.
Gruyaert, S; Lipok, J; Studnik, H, 2010
)
0.8
"Glyphosate, one of the most commonly used herbicides worldwide, has been considered as minimally toxic to humans."( Surfactant volume is an essential element in human toxicity in acute glyphosate herbicide intoxication.
Gil, HW; Hong, JR; Hong, SY; Lee, EY; Park, JS; Seok, SJ; Song, HY; Yang, JO, 2011
)
2.05
"Using glyphosate agrochemical components, we investigated their acute toxicity to juvenile Japanese medaka (Oryzias latipes) as well as their toxic impact at gene expression level on the liver tissues of adult medaka using DNA microarray."( Toxicity evaluation of glyphosate agrochemical components using Japanese medaka (Oryzias latipes) and DNA microarray gene expression analysis.
Arizono, K; Goto, Y; Kagami, Y; Kusano, T; Matsusaki, H; Nakamura, H; Tachikawa, K; Takumi, S; Uchida, M; Yamauchi, R, 2012
)
1.17
" Permeates of solutions with concentrations five times above the lethal doses (48 mg/l) did not present toxicity, pointing that all toxic compounds were removed at the same time."( Drinking water obtaining by nanofiltration from waters contaminated with glyphosate formulations: process evaluation by means of toxicity tests and studies on operating parameters.
Giannini, F; Padilla, AP; Saitúa, H, 2012
)
0.61
" Here we demonstrate that all formulations are more toxic than glyphosate, and we separated experimentally three groups of formulations differentially toxic according to their concentrations in ethoxylated adjuvants."( Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity.
Bernay, B; Mesnage, R; Séralini, GE, 2013
)
0.93
" Glyphosate herbicides such as brands of Roundup, are known to be toxic to daphnids."( Clone- and age-dependent toxicity of a glyphosate commercial formulation and its active ingredient in Daphnia magna.
Bøhn, T; Cuhra, M; Traavik, T, 2013
)
1.57
"5-fold more toxic than glyphosate-B."( Comparative toxicity of two glyphosate-based formulations to Eisenia andrei under laboratory conditions.
Basack, S; Casabé, N; Fuchs, J; Kesten, E; Oneto, ML; Piola, L, 2013
)
0.99
"Glyphosate, a post emergent herbicide, has become the backbone of no-till agriculture and is considered safe for animals."( Toxic and genotoxic effects of Roundup on tadpoles of the Indian skittering frog (Euflictis cyanophlyctis) in the presence and absence of predator stress.
Boro, F; Giri, A; Giri, S; Singha, U; Yadav, SS, 2013
)
1.83
" Reports of positive results for DNA damage endpoints indicate that glyphosate and GBFs tend to elicit DNA damage effects at high or toxic dose levels, but the data suggest that this is due to cytotoxicity rather than DNA interaction with GBF activity perhaps associated with the surfactants present in many GBFs."( Review of genotoxicity studies of glyphosate and glyphosate-based formulations.
Kier, LD; Kirkland, DJ, 2013
)
0.9
" In this study, the toxic effects of glyphosate and methidathion were evaluated comparatively on early developmental stages of 3 anurans-2 natural (Pelophylax ridibundus, Pseudepidalea viridis) and 1 laboratory species (Xenopus laevis)."( Comparative toxicity of methidathion and glyphosate on early life stages of three amphibian species: Pelophylax ridibundus, Pseudepidalea viridis, and Xenopus laevis.
Güngördü, A, 2013
)
0.93
" Our results show that G formulation had toxic effects while no effects were found with acid glyphosate and AMPA treatments."( Glyphosate commercial formulation causes cytotoxicity, oxidative effects, and apoptosis on human cells: differences with its active ingredient.
Chaufan, G; Coalova, I; Ríos de Molina, Mdel C,
)
1.79
" In this context the purpose of this study was to compare the genotoxicity of the active ingredient glyphosate with the formulated product RT in order to clarify whether the active ingredient and the surfactant of the RT formula may exert toxic effects on the DNA molecule in juveniles of fish Prochilodus lineatus."( Genotoxic effects of the herbicide Roundup Transorb and its active ingredient glyphosate on the fish Prochilodus lineatus.
Martinez, CB; Moreno, NC; Sofia, SH, 2014
)
0.85
" Presenting adverse effects of glyphosate and its formulations we focused on the role of glyphosate formulations in hormonal disorders by impeding the expression of steroidogenic acute regulatory protein and the inhibition of aromatase activity."( [Glyphosate and its formulations--toxicity, occupational and environmental exposure].
Bukowska, B; Kwiatkowska, M; Paweł, J, 2013
)
1.59
" Were examined Roundup toxic effects on Ruppia maritima specimens collected from Jansen Lagoon (São Luís, MA, Brazil) and acclimatized under laboratory conditions."( Using a toxicity test with Ruppia maritima (Linnaeus) to assess the effects of Roundup.
Castro, Ade J; Colares, IG; Cutrim, MV; Franco, TC; Luvizotto-Santos, R, 2015
)
0.42
" However, Cúspide 480SL contains an alkyl polyglycoside surfactant rather than the polyethoxylated tallow amine (POEA) surfactant used in other formulations and known to be more toxic to nonprimary producing aquatic organisms than glyphosate itself."( Toxicity of Cúspide 480SL® spray mixture formulation of glyphosate to aquatic organisms.
Currie, Z; Mahon, K; Poirier, D; Prosser, RS; Rodriguez-Gil, JL; Solomon, KR, 2015
)
0.85
" We observed that concentrations below those allowed by law were toxic regarding all parameters tested in this study, with the exception of mitochondrial function."( Cytotoxicity of the association of pesticides Roundup Transorb® and Furadan 350 SC® on the zebrafish cell line, ZF-L.
Boyle, RT; Goulart, TL; Souza, MM, 2015
)
0.42
" We have reviewed the toxic effects of GlyBH measured below regulatory limits by evaluating the published literature and regulatory reports."( Potential toxic effects of glyphosate and its commercial formulations below regulatory limits.
Defarge, N; Mesnage, R; Séralini, GE; Spiroux de Vendômois, J, 2015
)
0.71
" This study evaluates the acute toxic and sublethal effects (embryonic development, tadpole body size, tadpole swimming performance) of the mixture of the formulated glyphosate Roundup Active and Cosmo-Flux 411F to anuran embryos and tadpoles of four Colombian species under 96h laboratory standard tests and microcosms, which are more similar to field conditions as they include soil, sand and macrophytes."( Acute toxicity and sublethal effects of the mixture glyphosate (Roundup Active) and Cosmo-Flux 411F to anuran embryos and tadpoles of four Colombian species.
Bernal Bautista, MH; Henao Muñoz, LM; Montes Rojas, CM, 2015
)
0.86
" Its mechanism of action was thought to be specific only to plants and thus considered safe and non-toxic."( Glyphosate induces neurotoxicity in zebrafish.
Carneiro, B; Ochs, J; Roy, NM, 2016
)
1.88
"Players completed the Safe Play Questionnaire (0 = less knowledge, 7 = most knowledge) and Competitive Aggressiveness and Anger Scale (12 = less aggressive, 60 = most aggressive) at midseason."( Safe-Play Knowledge, Aggression, and Head-Impact Biomechanics in Adolescent Ice Hockey Players.
Guskiewicz, KM; Mihalik, JP; Pamukoff, DN; Pierce, AF; Register-Mihalik, JK; Schmidt, JD, 2016
)
0.43
"One-way analyses of variance were used to compare safe play knowledge and aggression between sexes."( Safe-Play Knowledge, Aggression, and Head-Impact Biomechanics in Adolescent Ice Hockey Players.
Guskiewicz, KM; Mihalik, JP; Pamukoff, DN; Pierce, AF; Register-Mihalik, JK; Schmidt, JD, 2016
)
0.43
"Coaches and sports medicine professionals should ensure that athletes of all levels, ages, and sexes have full knowledge of safe play and should consider aggression interventions for reducing head-impact severity among aggressive players during practice."( Safe-Play Knowledge, Aggression, and Head-Impact Biomechanics in Adolescent Ice Hockey Players.
Guskiewicz, KM; Mihalik, JP; Pamukoff, DN; Pierce, AF; Register-Mihalik, JK; Schmidt, JD, 2016
)
0.43
"Environmental contaminants produce multiple adverse consequences at individual, population and ecosystem levels."( Genotoxicity induced by Roundup® (Glyphosate) in tegu lizard (Salvator merianae) embryos.
Mudry, MD; Poletta, GL; Schaumburg, LG; Siroski, PA, 2016
)
0.71
" We conclude that glyphosate is developmentally toxic to the zebrafish heart."( Glyphosate induces cardiovascular toxicity in Danio rerio.
Anderson, A; Ochs, J; Roy, NM; Zambrzycka, E, 2016
)
2.21
" This classification is supported by the majority of scientific literature on the toxic effects of glyphosate."( Glyphosate: environmental contamination, toxicity and potential risks to human health via food contamination.
Bai, SH; Ogbourne, SM, 2016
)
2.09
" The results of the 90-days subchronic feeding study demonstrated that the GM soybean FG72 is as safe as the conventional non-GM soybean Jack."( No subchronic toxicity of multiple herbicide-resistant soybean FG72 in Sprague-Dawley rats by 90-days feeding study.
He, X; Huang, K; Liu, X; Xie, Z; Xu, W; Zou, S, 2018
)
0.48
" In natural-freshwater assays, at environmentally relevant concentrations, all three pesticides inhibited the preparasitic-stage endpoints; with carbendazim being the most toxic pesticide and the subsequent infectivity of larvae exposed in ovo the most sensitive endpoint."( Susceptibility of Chordodes nobilii (Gordiida, Nematomorpha) to three pesticides: Influence of the water used for dilution on endpoints in an ecotoxicity bioassay.
Achiorno, CL; de Villalobos, C; Ferrari, L, 2018
)
0.48
" It is concluded that no adverse effects related to the feeding of the NK603 maize cultivated with or without Roundup for up to 2 years were observed."( Lack of adverse effects in subchronic and chronic toxicity/carcinogenicity studies on the glyphosate-resistant genetically modified maize NK603 in Wistar Han RCC rats.
Aláčová, R; Alison, C; Alison, R; Babincová, J; Baumgärtner, W; Becker, K; de Vriend, H; Goedhart, PW; Jaďuďová, S; Kebis, A; Kleter, G; Kok, EJ; Krivošíková, Z; Lempp, C; Líšková, A; Mikušová, ML; Nadal, A; Pla, M; Pöting, A; Racovita, M; Rollerová, E; Schiemann, J; Schmicke, M; Schrenk, D; Spök, A; Steinberg, P; Szabova, E; Takácsová, M; Tulinská, J; van der Voet, H; Wilhelm, R; Zeljenková, D, 2019
)
0.74
"Glyphosate-based herbicides are broad-spectrum pesticides widely used in the world, which is considered a highly safe pesticide due to their target specificity, but recently, there has been an ongoing controversy regarding their carcinogenicity and possible side effects of glyphosate on human health."( Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve.
Gao, J; Hao, Y; Ni, H; Tao, L; Xu, W; Yang, Y; Zhang, Y, 2019
)
2.23
" Some of these factors include heat stroke leading to dehydration, toxic metals such as cadmium and arsenic, fluoride, low selenium, toxigenic cyanobacteria, nutritionally deficient diet and mycotoxins from mold exposure."( Glyphosate's Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin.
Gunatilake, S; Orlando, L; Seneff, S, 2019
)
1.96
"At present, the public is paying more attention to the adverse effects of pesticides on human and animal health and the environment."( Toxic effects of glyphosate on intestinal morphology, antioxidant capacity and barrier function in weaned piglets.
Bai, G; Fu, H; Qiu, S; Shi, B; Yang, Z; Zhou, R, 2020
)
0.9
" The toxicity of formulations is currently assessed substance by substance, neglecting possible combined effects in mixtures and many of the findings regarding the toxic effects of glyphosate and GBHs to human cells are inconsistent."( Comparative cyto- and genotoxicity assessment of glyphosate and glyphosate-based herbicides in human peripheral white blood cells.
Ádám, B; Budnik, LT; Nagy, K; Tessema, RA, 2019
)
0.96
" The aim of this study was to evaluate the acute toxic effects and the prevailing interactions on stage 36 tadpoles of the anuran species Rhinella arenarum when exposed to equitoxic and non-equitoxic combinations of these herbicide combinations."( Toxicity to Rhinella arenarum tadpoles (Anura, Bufonidae) of herbicide mixtures commonly used to treat fallow containing resistant weeds: glyphosate-dicamba and glyphosate-flurochloridone.
Brodeur, JC; Larramendy, ML; Ruiz de Arcaute, C; Soloneski, S, 2020
)
0.76
" Overall, the main toxic effects evaluated were mortality, abnormalities in the blood cells, developmental abnormalities, and behavior alterations."( The Toxic Effects of Glyphosate, Chlorpyrifos, Abamectin, and 2,4-D on Animal Models: A Systematic Review of Brazilian Studies.
Andrade-Barros, AI; Disner, GR; Falcão, MAP; Gomes, KS; Leite Dos Santos, NV; Lima, C; Lopes-Ferreira, M; Marcolino-Souza, M; Soares, ABS, 2021
)
0.94
" The objective of the present study was to characterize the sublethal effects of four environmental toxic compounds at two experimental pollution scenarios on the morphology, development and thyroid (T4), acetylcholinesterase (AChE) and glutathione S-transferase (GST) levels in Rhinella arenarum tadpoles."( Toxicity assessment at different experimental scenarios with glyphosate, chlorpyrifos and antibiotics in Rhinella arenarum (Anura: Bufonidae) tadpoles.
Attademo, AM; Cuzziol Boccioni, AP; Lajmanovich, RC; Martinuzzi, CS; Peltzer, PM, 2021
)
0.86
" Several transformation products of boscalid and fenbuconazole were estimated to be significantly more orally toxic than their parent residues."( Hazard assessment using an in-silico toxicity assessment of the transformation products of boscalid, pyraclostrobin, fenbuconazole and glyphosate generated by exposure to an advanced oxidative process.
Prosser, RS; Skanes, B; Warriner, K, 2021
)
0.82
" With the large-scale use of glyphosate-based herbicides (GBHs), their toxic effects on animals and plants have increasingly become a concern."( Effects of glyphosate-based herbicide-contaminated diets on reproductive organ toxicity and hypothalamic-pituitary-ovarian axis hormones in weaned piglets.
Fu, H; Gao, F; Qiu, S; Shan, A; Shi, B; Tan, P; Wang, X, 2021
)
1.3
" The resource, called Active & Safe Central (www."( Active & Safe Central: using a mixed-methods design and the RE-AIM framework to evaluate a sport and recreational injury prevention resource for practitioners in Canada.
Babul, S; Black, AM; Bruin, S; Pike, I; Richmond, SA, 2021
)
0.62
"A mixed-methods study design, guided by the RE-AIM (reach, effectiveness, adoption, implementation and maintenance) framework, was used to evaluate Active & Safe Central."( Active & Safe Central: using a mixed-methods design and the RE-AIM framework to evaluate a sport and recreational injury prevention resource for practitioners in Canada.
Babul, S; Black, AM; Bruin, S; Pike, I; Richmond, SA, 2021
)
0.62
" Active & Safe Central was reported as a credible source of evidence-based sport and recreational information and that the site would be recommended to others."( Active & Safe Central: using a mixed-methods design and the RE-AIM framework to evaluate a sport and recreational injury prevention resource for practitioners in Canada.
Babul, S; Black, AM; Bruin, S; Pike, I; Richmond, SA, 2021
)
0.62
" In this study, we used mature mouse oocytes to study the toxic effects of low-dose GBH exposure in vitro (0."( Melatonin rescues the reproductive toxicity of low-dose glyphosate-based herbicide during mouse oocyte maturation via the GPER signaling pathway.
Cao, M; Li, J; Qin, X; Wang, Y; Yang, F, 2021
)
0.87
" Several studies have concluded that herbicide concentrations right below the official safety limits induced toxic effects."( Trends in science on glyphosate toxicity: a scientometric study.
Carneiro, FM; de Moraes, JB; Rezende, ECN; Wastowski, IJ, 2021
)
0.94
"The toxic effects of the insecticides chlorpyrifos and cypermethrin, and the herbicide glyphosate on the growth, biovolume and ultrastructure of the green microalgae Selenastrum capricornutum were evaluated."( Toxic effects of chlorpyrifos, cypermethrin and glyphosate on the non-target organism Selenastrum capricornutum (Chlorophyta).
Asselborn, V; Fernández, C; Parodi, ER, 2021
)
1.1
" Glyphosate also seems to exert a significant toxic effect on neurotransmission and to induce oxidative stress, neuroinflammation and mitochondrial dysfunction, processes that lead to neuronal death due to autophagy, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders."( Toxic Effects of Glyphosate on the Nervous System: A Systematic Review.
Costas-Ferreira, C; Durán, R; Faro, LRF, 2022
)
1.97
" Therefore, the purpose of this study is to investigate the potentially toxic effects of glyphosate on scallops, an ecologically and economically important bivalve group."( Glyphosate exposure modulates lipid composition, histo-architecture and oxidative stress status and induces neurotoxicity in the smooth scallop Flexopecten glaber.
Al-Harbi, MS; Ben Ali, M; Chelbi, E; Hajji, T; Hedfi, A; Mhadhbi, L; Nechi, S; Rabeh, I; Telahigue, K, 2022
)
2.39
" This study aimed to investigate the toxic effects of glyphosate-based herbicide (GBH) on reproduction in mice exposed to 0 (control group), 50 (low-dose group), 250 (middle-dose group), and 500 (high-dose group) mg/kg/day GBH for 30 days."( Integrated metabolomics and transcriptomics reveal glyphosate based-herbicide induced reproductive toxicity through disturbing energy and nucleotide metabolism in mice testes.
Dong, Y; Li, G; Li, Y; Ma, S; Qi, L, 2023
)
1.41
" However, its potential vascular toxic effects in occupationally exposed populations remain unclear."( Glyphosate Causes Vascular Toxicity through Cellular Senescence and Lipid Accumulation.
Chen, W; Cheng, J; Li, Z; Lu, J; Tao, L; Wang, W; Xu, W; Zhang, C; Zhang, Y, 2023
)
2.35

Compound-Compound Interactions

Glyphosate's synergistic health effects in combination with exposure to other pollutants could result in renal damage consistent with CKDu in Sri Lanka.

ExcerptReferenceRelevance
" To advance isotope ratio analysis of an additional element, we present compound-specific (15)N/(14)N analysis of glyphosate and AMPA by a two step derivatization in combination with gas chromatography/isotope ratio mass spectrometry (GC/IRMS)."( Dual element ((15)N/(14)N, (13)C/(12)C) isotope analysis of glyphosate and AMPA by derivatization-gas chromatography isotope ratio mass spectrometry (GC/IRMS) combined with LC/IRMS.
Elsner, M; Jochmann, MA; Kujawinski, DM; Mogusu, EO; Wolbert, JB, 2015
)
0.87
"Both modalities effectively increased maximal strength and power output, whereas isokinetic resistance training, combined with eccentric overload, improved drop jump performance and induced greater muscle hypertrophy than traditional training in young ice hockey players."( Isokinetic resistance training combined with eccentric overload improves athletic performance and induces muscle hypertrophy in young ice hockey players.
Esping, T; Horwath, O; Olsson, MC; Paulsen, G; Seynnes, O, 2019
)
0.51
" Glyphosate's synergistic health effects in combination with exposure to other pollutants, in particular paraquat, and physical labor in the ubiquitous high temperatures of lowland tropical regions, could result in renal damage consistent with CKDu in Sri Lanka."( Glyphosate's Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin.
Gunatilake, S; Orlando, L; Seneff, S, 2019
)
2.87
"This study suggests that perinatal glyphosate exposure combined with a high-fat diet in adulthood increases the risk of jejunum inflammation and dysfunction."( Perinatal exposure to low doses of glyphosate-based herbicide combined with a high-fat diet in adulthood causes changes in the jejunums of mice.
Balbo, SL; Bonfleur, ML; Granzotto, DCT; Nogueira-Melo, GA; Panza, SB; Sant'Ana, DMG; Vargas, R, 2021
)
1.18

Bioavailability

Glyphosate exposure impairs metaphase II mouse oocyte quality. fortunei accelerated the dissipation of glyphosate, which showed a 4-fold decrease in its half-life. This promoted the rapid bioavailability of glyphosate-derived phosphorus in the water.

ExcerptReferenceRelevance
" Therefore, our study strongly suggests that glyphosate and its commercial formulations can control the toxicity as well as the bioavailability of heavy metals in aquatic ecosystems where both groups of chemicals can co-occur."( Influence of glyphosate and its formulation (Roundup) on the toxicity and bioavailability of metals to Ceriodaphnia dubia.
Chu, LM; Tsui, MT; Wang, WX, 2005
)
0.96
" We suggest that the presence of Roundup adjuvants enhances glyphosate bioavailability and/or bioaccumulation."( Differential effects of glyphosate and roundup on human placental cells and aromatase.
Benachour, N; Moslemi, S; Richard, S; Seralini, GE; Sipahutar, H, 2005
)
0.88
" In these studies, we examined the influence of the lepidopterean Bt Cry1Ac toxin on mineralization and bioavailability of the herbicide glyphosate in two different soils."( Influence of Cry1Ac toxin on mineralization and bioavailability of glyphosate in soil.
Accinelli, C; Koskinen, WC; Sadowsky, MJ, 2006
)
0.77
" Such results suggest that glyphosate in field may increase the mobility and bioavailability of Zn and correspondingly increase its environmental risk."( Cosorption of zinc and glyphosate on two soils with different characteristics.
Cang, L; Hao, XZ; Sun, RJ; Wang, YJ; Zhou, DM, 2006
)
0.94
"Sorption may affect the bioavailability and biodegradation of pesticides in soils."( Effects of surface sorption on microbial degradation of glyphosate.
Giesler, R; Nilsson, M; Nordgren, A; Persson, P; Schnurer, Y, 2006
)
0.58
" The increased efficacy of GLY-A versus GLY-IPA-1 and GLY-IPA-2 on velvetleaf is due to the greater rate of absorption and subsequent translocation of glyphosate out of the treated leaf."( Comparison of efficacy, absorption and translocation of three glyphosate formulations on velvetleaf (Abutilon theophrasti).
Belles, D; Brunk, G; Shaner, D; Westra, P, 2006
)
0.77
"5 and 11-fold higher, respectively) which potentially reduced the bioavailability of glyphosate to the microbial decomposers."( Environmental fate and non-target impact of glyphosate-based herbicide (Roundup) in a subtropical wetland.
Chu, LM; Tsui, MT, 2008
)
0.83
" The oral bioavailability of glyphosate was found to be 23."( Toxicokinetics of glyphosate and its metabolite aminomethyl phosphonic acid in rats.
Anadón, A; Bernal, JL; Castellano, VJ; Martin, MT; Martínez, M; Martínez, MA; Martínez-Larrañaga, MR; Nozal, MJ, 2009
)
0.98
" The fate of both herbicides was influenced by the type of plant organ in which herbicide was incorporated, because of differences in herbicides bioavailability and organs biodegradability, but not by adjuvants."( Delayed degradation in soil of foliar herbicides glyphosate and sulcotrione previously absorbed by plants: consequences on herbicide fate and risk assessment.
Barriuso, E; Doublet, J; Mamy, L, 2009
)
0.61
"6% higher than in the control which can be linked to (i) a higher glyphosate bioavailability in sewage sludge soil, which was triggered by the pre-sorption of phosphate originating from the sewage sludge and/or (ii) beneficial alterations of the sewage sludge to the physical-chemical characteristics of the soil."( Single application of sewage sludge--impact on the quality of an alluvial agricultural soil.
Dörfler, U; Hagn, A; Lobnik, F; Schloter, M; Schroll, R; Suhadolc, M, 2010
)
0.6
" These results demonstrate that GPS could control the toxicity as well as the bioavailability of heavy metals in soil solutions where both GPS and heavy metals often coexist."( Does glyphosate impact on Cu uptake by, and toxicity to, the earthworm Eisenia fetida?
Sun, RJ; Wang, YJ; Yu, YC; Zhang, HL; Zhou, CF; Zhou, DM; Zhu, XD, 2012
)
0.89
" With glyphosate-B toxic effects were observed at higher doses, close to its LC50, suggesting that the higher toxicity of formulate A could be attributed to the effects of some of the so-called "inert ingredients", either due to a direct intrinsic toxicity, or to an enhancement in the bioavailability and/or bioaccumulation of the active ingredient."( Comparative toxicity of two glyphosate-based formulations to Eisenia andrei under laboratory conditions.
Basack, S; Casabé, N; Fuchs, J; Kesten, E; Oneto, ML; Piola, L, 2013
)
1.16
" Due to the chemical structure of GPS, it can form complexes of heavy metals and interface their bioavailability in soil environment."( Subacute toxicity of copper and glyphosate and their interaction to earthworm (Eisenia fetida).
Li, CC; Sun, RJ; Wang, YJ; Yu, YC; Zhou, CF; Zhou, DM, 2013
)
0.67
" Thus, the herbicide glyphosate can reduce the toxicity and bioavailability of Cd in the soil ecosystems at both short- and long-term exposures."( Inhibition effect of glyphosate on the acute and subacute toxicity of cadmium to earthworm Eisenia fetida.
Fan, GP; Li, CC; Liu, C; Qin, WX; Sun, RJ; Wang, YJ; Zhou, CF; Zhou, DM, 2014
)
1.04
" Due to their chemical similarities, PO4(3-) and glyphosate compete for soil adsorbing sites, with PO4(3-) fertilization increasing glyphosate bioavailability in the soil solution."( Consequences of phosphate application on glyphosate uptake by roots: Impacts for environmental management practices.
Gomes, MP; Juneau, P; Labrecque, M; Lucotte, M; Maccario, S, 2015
)
0.94
" fortunei accelerated the dissipation of glyphosate, which showed a 4-fold decrease in its half-life; this promoted the rapid bioavailability of glyphosate-derived phosphorus in the water."( Impact of multiple anthropogenic stressors on freshwater: how do glyphosate and the invasive mussel Limnoperna fortunei affect microbial communities and water quality?
Cataldo, D; Di Fiori, E; Pizarro, H; Ramírez, M; Rodríguez, P; Sinistro, R; Vinocur, A, 2016
)
0.94
" Glyphosate has an amino acid-like structure that is highly polar and shows low bioavailability following oral ingestion and low systemic toxicity following intravenous exposures."( The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial tissues.
Cai, J; Donovan, MD; He, S; Huang, J; Li, G; Si, L; Wang, Z; Xu, J, 2016
)
1.59
" Little is known about the bioavailability and ecotoxicity of glyphosate-Cu(II) complexes to aquatic organisms."( Behavioral responses of juvenile Daphnia magna after exposure to glyphosate and glyphosate-copper complexes.
Hansen, LR; Roslev, P, 2016
)
0.91
" However, AM method has several limitations such as uncertainty regarding the bioavailability and amount of pesticides ingested."( Continuous liquid feeding: New method to study pesticides toxicity in Drosophila melanogaster.
Bianchini, MC; Caurio, AC; Denardin, ELG; Gayer, MC; Gonçalves, MB; Puntel, RL; Roehrs, R; Soares, JJ; Soares, SJ, 2017
)
0.46
" However, assessing glyphosate bioavailability to plants from soil residues remains challenging."( Assessing plant-available glyphosate in contrasting soils by diffusive gradient in thin-films technique (DGT).
Bennett, W; Lombi, E; Rose, MT; Styles, G; Tavakkoli, E; Van Zwieten, L; Weng, Z, 2019
)
1.14
" Microplastics can have a direct negative effect, but they can also potentially modify the toxicity and bioavailability of pollutants."( Microplastics modify the toxicity of glyphosate on Daphnia magna.
Sommaruga, R; Zocchi, M, 2019
)
0.79
" Our work shows for the first time that glyphosate exposure impairs metaphase II mouse oocyte quality via two mechanisms: 1) disruption of the microtubule organizing center and chromosomes such as anomalous pericentrin formation, spindle fiber destruction and disappearance, and defective chromosomal alignment and 2) substantial depletion of intracellular zinc bioavailability and enhancement of reactive oxygen species accumulation."( Glyphosate Induces Metaphase II Oocyte Deterioration and Embryo Damage by Zinc Depletion and Overproduction of Reactive Oxygen Species.
Abu-Soud, HM; Bai, D; Chatzicharalampous, C; Khan, SN; Kohan-Ghadr, HR; Morris, RT; Yahfoufi, ZA, 2020
)
2.27
" In this study, as witnessed via characterizing the bioavailability and phytotoxicity of glyphosate to cowpea plants in soils applied with or without earthworm casts (EWCs), EWCs could significantly facilitate glyphosate desorption from soil, thus enhance its bioaccessibility, nonetheless, sharply decreased rather than increased the accumulation of glyphosate in cowpea plants via reducing the residue pool of glyphosate in the soil."( Earthworm casts restrained the accumulation and phytotoxicity of soil glyphosate to cowpea (Vigna unguiculata (L.) Walp.) plants.
Jiang, L; Liang, J; Lin, Y; Pan, B; Wang, B; Yang, Y, 2021
)
1.08
" It sorbs strongly to particles in soil and sediments and this reduces bioavailability so that exposures to non-target organisms in the environment are acute and decrease with half-lives in the order of hours to a few days."( Ecotoxicology of Glyphosate, Its Formulants, and Environmental Degradation Products.
Duke, SO; Prosser, RS; Rodríguez-Gil, JL; Solomon, KR, 2021
)
0.96
"Although Glyphosate-based herbicides are often marketed as environmentally friendly and easily biodegradable, its bioavailability and risks to wildlife raise significant concerns."( Glyphosate, AMPA and glufosinate in soils and earthworms in a French arable landscape.
Bertrand, C; Bretagnolle, V; Coeurdassier, M; Delhomme, O; Deschamps, M; Fritsch, C; Gaba, S; Millet, M; Nélieu, S; Pelosi, C, 2022
)
2.58
" Hence, we tested degradation of five HILs with the glyphosate anion, their bioavailability in soil, toxicity towards microorganisms, impact on the biodiversity and the abundance of phnJ and soxA genes."( Glyphosate versus glyphosate based ionic liquids: Effect of cation on glyphosate biodegradation, soxA and phnJ genes abundance and microbial populations changes during soil bioaugmentation.
Batycka, M; Cajthaml, T; Chrzanowski, Ł; Dabert, M; Heipieper, HJ; Homa, J; Niemczak, M; Parus, A; Táncsics, A; Trzebny, A; Wilms, W; Woźniak-Karczewska, M, 2023
)
2.6
"Biogenic manganese oxides (BMO) are widely distributed in groundwater and provides promise for adsorbing and oxidizing a wide range of micropollutants, however, the continuous biodegradation and bioavailability of micropollutants via cycle biogenic Mn(II) oxidation remains to be elucidated."( Detoxification and metabolism of glyphosate by a Pseudomonas sp. via biogenic manganese oxidation.
Ji, Q; Jin, B; Wang, H; Yu, J, 2023
)
1.19
" In this study, in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AMPA in soils and their adverse effects on plant growth."( Kinetics of glyphosate and aminomethylphosphonic acid sorption onto montmorillonite clays in soil and their translocation to genetically modified corn.
Phillips, TD; Rivenbark, KJ; Wang, M, 2024
)
1.82

Dosage Studied

The results show that the glyphosate weed control programs compared to the conventional methods decreased not only the number of herbicide applications but equally in magnitude decreased the dosage of active ingredients. The dose-response assays showed that the biotypes were highly resistant to glyphosate.

ExcerptRelevanceReference
" Although there was no appreciable inhibition of the reduction of pyridine nucleotide at dosage levels less than 150 mg PMG/kg, the extent of inhibition increased as the dose was raised to 240 mg PMG/kg."( Inhibition of succinate-linking reduction of pyridine nucleotide in rat liver mitochondria 'in vivo' by N-(phosphonomethyl)glycine.
Bababunmi, EA; Olorunsogo, OO, 1980
)
0.26
" CP4 EPSPS degrades readily in simulated gastric and intestinal fluids, suggesting that this protein will be degraded in the mammalian digestive tract upon ingestion as a component of food or feed, There were no deleterious effects due to the acute administration of CP4 EPSPS to mice by gavage at a high dosage of 572 mg/kg body wt, which exceeds 1000-fold tha anticipated consumption level of food products potentially containing CP4 EPSPS protein."( The expressed protein in glyphosate-tolerant soybean, 5-enolpyruvylshikimate-3-phosphate synthase from Agrobacterium sp. strain CP4, is rapidly digested in vitro and is not toxic to acutely gavaged mice.
Bailey, MR; Burnette, BL; Fuchs, RL; Hammond, BG; Harrison, LA; Mitsky, TA; Naylor, MW; Nickson, TE; Nida, DL; Padgette, SR; Ream, JE; Taylor, ML, 1996
)
0.6
" The provocative dose causing a 20% fall in the forced expiratory volume in one second (PD20) was significantly lower in ice hockey players than in floor ball players, but there was no significant difference in the dose-response slopes between the two groups."( High prevalence of bronchial hyperresponsiveness and asthma in ice hockey players.
Comminot, C; Kuhn, M; Leuppi, JD; Reinhart, WH, 1998
)
0.3
" There is evidence of a dose-response gradient as predicted probability of injury decreases with increasing levels of sport specific training."( Risk factors for groin injuries in hockey.
Emery, CA; Meeuwisse, WH, 2001
)
0.31
" We investigated these claims by examining dose-response curves of barley plants treated with glyphosate at various calcium concentrations in the presence of these adjuvants."( Adjuvant influence on glyphosate efficacy in the presence of CA2+.
Gaudry, JC; Gauvrit, C, 2001
)
0.84
" This direct comparison conclusively confirms that horseweed plants collected in western Tennessee in 2002 are resistant to 4 times the normal application dosage of glyphosate."( Shikimate accumulates in both glyphosate-sensitive and glyphosate-resistant horseweed (Conyza canadensis L. Cronq.).
Hayes, RM; Main, CL; Massey, JH; Mueller, TC; Stewart, CN, 2003
)
0.8
"A suite of dose-response bioassays with white mustard (Sinapis alba L) and sugar beet (Beta vulgaris L) in the greenhouse and with three herbicides was used to analyse how the fluorescence induction curves (Kautsky curves) were affected by the herbicides."( Linking fluorescence induction curve and biomass in herbicide screening.
Christensen, MG; Streibig, JC; Teicher, HB, 2003
)
0.32
" Dose-response assays showed significant differences between low and high spraying volume treatments as expected, the former being much more effective than the latter."( The correlation of the spraying volume with herbicide adherence and herbicide penetration in glyphosate treatments.
Bastida, F; Menéndez, J, 2004
)
0.54
" Dose-response experiments established that the glyphosate rate causing 50% mortality (LD(50)) for the resistant (R) biotype is 14 times greater than for the susceptible (S) biotype."( Glyphosate, paraquat and ACCase multiple herbicide resistance evolved in a Lolium rigidum biotype.
Cairns, A; Powles, S; Yu, Q, 2007
)
2.04
" During a 14-d holding period, we observed dose-response relationships in the ability of hatchlings to right themselves when turned on their backs."( Toxicity of glyphosate as Glypro and LI700 to red-eared slider (trachemys scripta elegans) embryos and early hatchlings.
Bickham, J; Doelling-Brown, P; Matson, C; Sparling, DW, 2006
)
0.71
"0% of the recommended dosage (i."( Foliar-applied glyphosate substantially reduced uptake and transport of iron and manganese in sunflower (Helianthus annuus L.) plants.
Cakmak, I; Eker, S; Erenoglu, B; Ozturk, L; Romheld, V; Yazici, A, 2006
)
0.69
" Based on a Petri dish dose-response bioassay, the OR and the SF populations were two and fivefold more resistant to glyphosate when compared to the susceptible (S) population, respectively; however, based on a whole-plant dose-response bioassay, both OR and SF populations were fivefold more resistant to glyphosate than the S population, implying that different resistance mechanisms might be involved."( Investigating the mechanisms of glyphosate resistance in Lolium multiflorum.
Colquhoun, J; Mallory-Smith, CA; Park, KW; Perez-Jones, A; Polge, N, 2007
)
0.83
" Dose-response assays were conducted to characterize the extreme populations further, and shikimate accumulation in vivo was determined using a spectrophotometric method."( Response of wild Brassica juncea populations to glyphosate.
Huangfu, CH; Qiang, S; Song, XL; Zhang, HJ, 2007
)
0.6
" Human cadaver skin was dosed (approximately 375microg) of [14C]-glyphosate on 3cm2 per skin."( Skin decontamination of glyphosate from human skin in vitro.
Chan, HP; Hui, X; Maibach, HI; Zhai, H, 2008
)
0.89
" Dose-response experiments indicated a glyphosate tolerance ratio [ED(50)(C."( Nontarget mechanims involved in glyphosate tolerance found in Canavalia ensiformis plants.
Cruz-Hipolito, H; De Prado, R; Heredia, A; Osuna, MD; Ruiz-Santaella, JP, 2009
)
0.91
" The aim of this paper is to assess selectivity of various herbicides in grass seed crops by using dose-response curves."( Using a selectivity index to evaluate logarithmic spraying in grass seed crops.
Jensen, JE; Mathiesen, TJ; Ritz, C; Streibig, JC; Tind, T, 2009
)
0.35
" Single-species tests are useful because they are inexpensive, can demonstrate clear dose-response patterns uncomplicated by other factors influencing growth, and are able to provide a measure of the sensitivity of a given species to glyphosate and atrazine."( Comparison of the effects of glyphosate and atrazine herbicides on nontarget plants grown singly and in microcosms.
Boutin, C; Dalton, RL, 2010
)
0.83
" The two pesticides were applied in equal dosage to a structured, tile-drained soil, and the concentration of the pesticides was then measured in drainage water sampled flow-proportionally."( Transport modes and pathways of the strongly sorbing pesticides glyphosate and pendimethalin through structured drained soils.
de Jonge, LW; Ernsten, V; Hansen, N; Jacobsen, OH; Kjær, J; Olsen, P, 2011
)
0.61
" Experiments on an SSF planted with Phragmites australis and an unplanted SSF with mainly vertical flow conditions to which Glyphosate was continuously dosed showed that in the planted SSF Glyphosate retardation exceeds 54% compared to 14% retardation in the unplanted SSF."( Comparative studies on the retardation and reduction of glyphosate during subsurface passage.
Grützmacher, G; Heise, S; Krause, B; Litz, NT; Weigert, A, 2011
)
0.82
" For this mixture, a dose-response approach was used to treat mesocosms with the ERCs of each herbicide as the base concentration."( Effects of glyphosate and two herbicide mixtures on microbial communities in prairie wetland ecosystems: a mesocosm approach.
Cessna, AJ; Glozier, N; Lawrence, JR; Sura, S; Tumber, V; Waiser, M,
)
0.52
" A part of the title compounds such as IIa-g, IIk, IIo, and IIr exhibited significant postemergence herbicidal activity against Abutilon theophrasti, Brassica juncea, Amaranthus retroflexus, and Eclipta prostrate at a dosage of 150 g ai/ha."( Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
He, HF; He, HW; Peng, H; Tan, XS; Wang, W; Zuo, N, 2012
)
0.38
" The results show that the glyphosate weed control programs compared to the conventional methods decreased not only the number of herbicide applications but equally in magnitude decreased the dosage of active ingredients."( Yield of glyphosate-resistant sugar beets and efficiency of weed management systems with glyphosate and conventional herbicides under German and Polish crop production.
Kordas, L; Kraus, J; Matzk, A; Nichterlein, H; Stibbe, C, 2013
)
1.1
" Random occurrences of cardiovascular malformations were observed across all dose groups (including controls) and did not exhibit a dose-response relationship."( Evaluation of developmental toxicity studies of glyphosate with attention to cardiovascular development.
DeSesso, JM; Kimmel, CA; Kimmel, GL; Williams, AL, 2013
)
0.65
" Land use, localized dosage history, depth below ground and other factors likely control the occurrence of detectable glyphosate residues in groundwater."( Residues of the herbicide glyphosate in riparian groundwater in urban catchments.
Bickerton, G; Brown, SJ; Roy, JW; Van Stempvoort, DR, 2014
)
0.91
" Mean glyphosate residues in larvae were comparable at 4 days after spray application in the exposure study and also following dosing at a level calculated from the mean measured levels in pollen and nectar, showing the applicability and robustness of the approach for dose setting with honeybee brood studies."( Evaluating exposure and potential effects on honeybee brood (Apis mellifera) development using glyphosate as an example.
Doering, J; Levine, SL; Manson, P; Norman, S; Sutton, P; Thompson, HM; von Mérey, G, 2014
)
1.1
" Higher dosage levels typically contributed to an increase in the magnitude of phenotypic changes."( Sub-lethal glyphosate exposure alters flowering phenology and causes transient male-sterility in Brassica spp.
Bollman, M; Londo, JP; McKinney, J; Sagers, C; Schwartz, M; Watrud, L, 2014
)
0.79
" At the same time there was a clear dose-response effect for VisionMax(®) to increase thyroid hormone receptor β in tadpole brain (F(2,69)=3."( Effects of glyphosate-based herbicides on survival, development, growth and sex ratios of wood frogs (Lithobates sylvaticus) tadpoles. I: chronic laboratory exposures to VisionMax®.
Doe, K; Jackman, P; Lanctôt, C; Navarro-Martín, L; Park, BJ; Pauli, BD; Trudeau, VL, 2014
)
0.79
" Dose-response experiments yielded ED50 values (50% effect dose) in the range of 38-550 ga."( Glyphosate spray drift in Coffea arabica - sensitivity of coffee plants and possible use of shikimic acid as a biomarker for glyphosate exposure.
Cedergreen, N; Schrübbers, LC; Sørensen, JC; Valverde, BE, 2014
)
1.85
" Dose-response bioassays, glyphosate absorption and translocation experiments, herbicide target (EPSPS) gene sequence analysis, and gene amplification assays were conducted."( EPSPS Gene Amplification in Glyphosate-Resistant Italian Ryegrass (Lolium perenne ssp. multiflorum) Populations from Arkansas (United States).
Burgos, NR; Dayan, FE; Salas, RA; Scott, RC, 2015
)
1.01
" elata populations, one glyphosate resistant (GR) and one glyphosate susceptible (GS), were studied in detail for a dose-response experiment and for resistance mechanism."( Confirmation and mechanism of glyphosate resistance in tall windmill grass (Chloris elata) from Brazil.
Brunharo, CA; Carrijo, DR; Christoffoleti, PJ; de Melo, MS; Gaines, TA; Nicolai, M; Nissen, SJ; Patterson, EL, 2016
)
1.03
" Transgenic rice lines were tested by herbicide bioassay and it was confirmed that they could tolerate up to 3360 g/ha glyphosate, a dosage four-fold that of the recommended agricultural application level."( A Novel Naturally Occurring Class I 5-Enolpyruvylshikimate-3-Phosphate Synthase from Janibacter sp. Confers High Glyphosate Tolerance to Rice.
Cui, Y; Lin, YJ; Liu, ZD; Yi, SY; Zhao, Y; Zhou, F, 2016
)
0.85
" The comparison between the concentration of glyphosate and administered dosage did not show the correlation, which suggests further investigation on the effects of surfactants in glyphosate from different vendors."( Determination of glyphosate and its metabolite in emergency room in Korea.
Chung, H; Han, J; Hong, Y; Jeong, WJ; Lee, KS; Moon, H; Yang, S, 2016
)
1.03
" Dose-response assays confirmed the presence of high levels of herbicide resistance in the five selected populations (≥ 25-fold compared to a susceptible standard)."( Multiple-Herbicide Resistance Is Widespread in Roadside Palmer Amaranth Populations.
Bagavathiannan, MV; Norsworthy, JK, 2016
)
0.43
" However, effluent from all the test models including those dosed with high GCH concentration of 7200 mg L(-1) do not pose any threat in terms of infiltration or deterioration associated with salinity although, there are indications that high dosage of the herbicide could lead to an elevated electrical conductivity of the recycled water."( Stormwater harvesting from landscaped areas: effect of herbicide application on water quality and usage.
Charlesworth, SM; Coupe, SJ; Mbanaso, FU; Nnadi, EO, 2016
)
0.43
" A linear dose-response effect of field hockey (hours/week x years) within the field hockey players could not be demonstrated (OR=1."( Dupuytren disease is highly prevalent in male field hockey players aged over 60 years.
Broekstra, DC; Harder, T; Lanting, R; Smits, I; van den Heuvel, ER; Werker, PMN, 2018
)
0.48
" Dose-response assays confirmed resistance in seven different accessions."( First confirmation and characterization of target and non-target site resistance to glyphosate in Palmer amaranth (Amaranthus palmeri) from Mexico.
Alcántara-de la Cruz, R; Cruz-Hipolito, HE; De Prado, R; Dominguez-Valenzuela, JA; Fernández-Moreno, PT; Gherekhloo, J; Sánchez-González, E, 2017
)
0.68
" Metabolomics analysis combined with correlation network analysis uncovered significant perturbations in oxidative stress, energy metabolism, amino acids metabolism and nucleosides metabolism in glyphosate dosed fish, which provide new clues to the toxicity of glyphosate."( Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure.
Fu, YH; Jiang, L; Li, MH; Ruan, LY; Wang, JS; Zhao, H; Zhou, JW, 2017
)
0.88
" Dose-response and shikimate accumulation assays confirmed resistance of the resistant (R) biotypes."( Pro-106-Ser mutation and EPSPS overexpression acting together simultaneously in glyphosate-resistant goosegrass (Eleusine indica).
Alcántara-de la Cruz, R; Cruz-Hipolito, HE; De Prado, R; Domínguez-Valenzuela, JA; Fernández-Moreno, PT; Gherekhloo, J; Sánchez-González, E, 2017
)
0.68
" Dose-response experiments revealed that the MR1 population was 45."( Multiple resistance to glyphosate, paraquat and ACCase-inhibiting herbicides in Italian ryegrass populations from California: confirmation and mechanisms of resistance.
Jasieniuk, M; Jugulam, M; Nandula, V; Putta, K; Tehranchian, P, 2018
)
0.79
" The dose-response assays showed that the biotypes were highly resistant to glyphosate."( Transgene escape and persistence in an agroecosystem: the case of glyphosate-resistant Brassica rapa L. in central Argentina.
Cantamutto, M; Carbonell, FT; Pandolfo, CE; Poverene, M; Presotto, A; Ureta, S, 2018
)
0.95
" In particular, we criticise an arbitrary attenuation by the authorities of the power of statistical analyses; their disregard of existing dose-response relationships; their unjustified claim that the doses used in the mouse carcinogenicity studies were too high and their contention that the carcinogenic effects were not reproducible by focusing on quantitative and neglecting qualitative reproducibility."( Pesticides and public health: an analysis of the regulatory approach to assessing the carcinogenicity of glyphosate in the European Union.
Burtscher-Schaden, H; Clausing, P; Robinson, C, 2018
)
0.69
" The dose-response behavior was not observed in either CA or SCE."( Cytogenetic damage in peripheral blood cultures of Chaetophractus villosus exposed in vivo to a glyphosate formulation (Roundup).
Luaces, JP; Merani, MS; Mudry, MD; Palermo, AM; Rossi, LF, 2018
)
0.7
" One cohort was continuously dosed until sexual maturity (6-week cohort) and another cohort was continuously dosed until adulthood (13-week cohort)."( The Ramazzini Institute 13-week study on glyphosate-based herbicides at human-equivalent dose in Sprague Dawley rats: study design and first in-life endpoints evaluation.
Belpoggi, F; Bua, L; Chen, J; Dinelli, G; Falcioni, L; Galeati, G; Hu, J; Landrigan, PJ; Lorenzetti, S; Mandrioli, D; Manservisi, F; Mantovani, A; Miglio, R; Panzacchi, S; Perry, MJ; Spinaci, M, 2018
)
0.75
": Future research using larger sample sizes is warranted to evaluate the potential dose-response relationship between number of prior concussions and NPC."( A History of Concussion Does Not Lead to an Increase in Ocular Near Point of Convergence.
Dierijck, J; Smirl, J; van Donkelaar, P; Wright, A, 2018
)
0.48
" Our assessment also indicates a non-monotonic dose-response and variability in the effects among colonies."( Glyphosate affects the larval development of honey bees depending on the susceptibility of colonies.
Farina, WM; Ilina, N; Pagano, EA; Vázquez, DE; Zavala, JA, 2018
)
1.92
" Glyphosate resistance was confirmed for the GRP population by dose-response assays."( Reduced Absorption and Impaired Translocation Endows Glyphosate Resistance in Amaranthus palmeri Harvested in Glyphosate-Resistant Soybean from Argentina.
Alcántara-de la Cruz, R; Bracamonte, E; De Prado, R; Garcia, MJ; Palma-Bautista, C; Rojano-Delgado, AM; Torra, J, 2019
)
1.67
" The use of biomarkers as a tool to assess responses of organisms exposed to pollutants requires the understanding of their natural fluctuation and the dose-response relationship."( Seasonal variations in the dose-response relationship of acetylcholinesterase activity in freshwater fish exposed to chlorpyrifos and glyphosate.
Bernal-Rey, DL; Cantera, CG; Dos Santos Afonso, M; Menéndez-Helman, RJ, 2020
)
0.76
" Moreover, the deleterious effects of GLY exposure on human health were observed in epidemiological studies; however, most of these studies have not determined the GLY dosage to confirm a direct effect."( Effects of glyphosate exposure on human health: Insights from epidemiological and in vitro studies.
Agostini, LP; Cardoso, RC; Dettogni, RS; Dos Reis, RS; Dos Santos, EVW; Garcia, FM; Graceli, JB; Louro, ID; Stur, E; Ventorim, DP, 2020
)
0.95
" Progenies were subjected to herbicide dose-response studies following drift selection."( Herbicide drift exposure leads to reduced herbicide sensitivity in Amaranthus spp.
Amundsen, KL; Gaines, TA; Kruger, GR; Luck, JD; Vieira, BC; Werle, R, 2020
)
0.56
" aeruginosa, photosynthetic activity indicated by Fv/Fm, and microcystin production ability showed a typical U-shaped hormetic dose-response to glyphosate exposure."( Proteomic mechanisms for the combined stimulatory effects of glyphosate and antibiotic contaminants on Microcystis aeruginosa.
Gao, B; Liu, Y; Xu, S; Zhang, J, 2021
)
1.06
" Prior to resistance monitoring trials, dose-response assays were conducted to determine a single dose of glyphosate or chlorimuron-ethyl to discriminate resistant and susceptible populations."( Monitoring Glyphosate- and Chlorimuron- resistant Conyza spp. Populations in Brazil.
Cavenaghi, AL; Christoffoleti, PJ; Gonçalves Netto, A; Melo, MSC; Mendes, RR; Nicolai, M; Oliveira Junior, RS; Ovejero, RFL; Picoli Junior, GJ; Silva, VFV; Takano, HK, 2021
)
1.22
" The level of exposure to the herein assessed pesticides was quantified at the end of the incubation period; it was done by dosing its concentration in eggshells."( The exposure in ovo of embryos belonging to Amazonian turtle species Podocnemis expansa (Testudines) to commercial glyphosate and fipronil formulations impairs their growth and changes their skeletal development.
Ambrósio, IS; Araújo, APDC; Costa, MS; de Andrade, DV; de Castro Pereira, C; de Faria, AM; de Lima, PN; de Melo E Silva, D; de Moura Bife Castilho, L; Dos Santos, ALR; Hirano, LQL; Malafaia, G; Mendonça, JDS; Santos, ALQ; Vieira, LG, 2022
)
0.93
" We observed a dose-response relationship between consumption of whole grain bread and higher urinary glyphosate concentrations."( Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Arbuckle, TE; Ashley-Martin, J; Bienvenu, JF; Borghese, MM; Bouchard, MF; Brion, O; Fisher, M; Foster, WG; Gaudreau, E; Huang, R; Lanphear, B; MacPherson, S; Owen, J, 2023
)
1.39
" No clear dose-response effect was seen."( Exposure to phenoxyacetic acids and glyphosate as risk factors for non-Hodgkin lymphoma- pooled analysis of three Swedish case-control studies including the sub-type hairy cell leukemia.
Carlberg, M; Eriksson, M; Hardell, L; Nordström, M, 2023
)
1.19
" At dosing completion, females were housed with unexposed males and divided into Cohort 1 who were euthanized at gestation day 14 (n = 10 per treatment) and Cohort 2 who completed gestation (n = 10 per treatment)."( Maternal pre-conceptional glyphosate exposure impacts the offspring hepatic and ovarian proteome.
Keating, AF; Novbatova, G; Sayadi, M; Severin, A; Timme, K, 2023
)
1.21
" The dose-response relationships between GLY exposure with health outcomes and potential mediators were analyzed using restricted cubic spline (RCS) regression."( Association of glyphosate exposure with multiple adverse outcomes and potential mediators.
Huang, G; Jiang, L; Lei, D; Li, W; Lin, Y; Lu, P; Lv, J; Qin, YJ; Tang, N; Xu, F, 2023
)
1.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (3)

RoleDescription
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitorAn EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19).
herbicideA substance used to destroy plant pests.
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
phosphonic acidA phosphorus oxoacid that consists of a single pentavalent phosphorus covalently bound via single bonds to a single hydrogen and two hydroxy groups and via a double bond to an oxygen. The parent of the class of phosphonic acids.
glycine derivativeA proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (6)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferaseAgrobacterium sp. CP4IC50 (µMol)5,580.0000160.00005,580.000011,000.0000AID977608
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferaseAgrobacterium sp. CP4IC50 (µMol)5,580.0000160.00005,580.000011,000.0000AID977608
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (239)

Assay IDTitleYearJournalArticle
AID1081422Drug absorption in Conyza sumatrensis (tall fleabane) assessed as translocation in treated leaf at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1104243Toxicity against Festuca rubra applied using logarithmic sprayer2009Pest management science, Nov, Volume: 65, Issue:11
Using a selectivity index to evaluate logarithmic spraying in grass seed crops.
AID1091001Induction of shikimate accumulation in Abutilon theophrasti (velvetleaf) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 2 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082938Post-emergence herbicidal activity against Ammannia baccifera assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1091010Induction of shikimate accumulation in Vigna unguiculata (cowpea) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 64 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1110709Post-emergence herbicidal activity against Amaranthus viridis assessed as reduction of seed germination at 1.22 ppm after 5 to 25 days by pot test2000Farmaco (Societa chimica italiana : 1989), May, Volume: 55, Issue:5
Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
AID1103027Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.68 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091043Drug level in non glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102982Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 0.45 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103038Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 0.45 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103007Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 1.68 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091009Induction of shikimate accumulation in non glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 27 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081416Drug absorption in Conyza bonariensis (hairy fleabane) assessed as translocation in rest of plant at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1103000Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.25 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102989Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.45 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102981Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 0.84 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082287Toxicity in young Olea europaea (olive) plants assessed as induction of chronic photoinhibition of photosystem II at 3 kg/ha measured 60 days post dose in presence of oil Olea europaea (olive)-mill waste2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1102464Stimulation of shoot elongation in Lactuca sativa (lettuce) at 10'-4 to 10'-9 M after 5 days relative to control2003Journal of agricultural and food chemistry, Oct-08, Volume: 51, Issue:21
Lignans and neolignans from Brassica fruticulosa: effects on seed germination and plant growth.
AID1081426Ratio of ED50 for hairy fleabane Conyza bonariensis to ED50 for tall fleabane Conyza sumatrensis2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1082942Post-emergence herbicidal activity against Amaranthus retroflexus assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1103035Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 1.68 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082937Post-emergence herbicidal activity against Monochoria vaginalis assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1103017Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.45 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091015Ratio of compound to AMPA level in Senna obtusifolia (sicklepod) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081415Drug absorption in Conyza sumatrensis (tall fleabane) assessed as translocation in root at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1103043Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.25 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103004Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 9 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103034Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 2.52 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103024Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 9 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091054Growth inhibition of Senna obtusifolia (sicklepod) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103018Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 3.36 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1090998Induction of shikimate accumulation in Lolium multiflorum (Italian ryegrass) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 904 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081424Ratio of ED50 for hairy fleabane Conyza canadensis to ED50 for tall fleabane Conyza sumatrensis2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1103054Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 3.36 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082277Toxicity in young Olea europaea (olive) plants assessed as reduction in intracellular CO2 level at 3 kg/ha measured 15 days post dose in presence of oil Olea europaea (olive)-mill waste2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1091040Drug level in Senna occidentalis (coffee senna) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103002Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.45 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID628617Antimelanogenic activity in non-melanized Cryptococcus neoformans var. grubii assessed as inhibition of pigmentation at 200 ug/mL after 10 days by microtiter plate assay in presence of 1 mM catecholamine2011Bioorganic & medicinal chemistry, Nov-15, Volume: 19, Issue:22
Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans.
AID1091047Growth inhibition of Conyza canadensis (horseweed) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1105559Inhibition of Thlaspi arvense CPR-fused CYP71B1 expressed in Escherichia coli DH5alpha assessed as conversion of benzo(a)pyrene to 3-hydroxybenzo(a)pyrene1998Biochemical and biophysical research communications, Mar-06, Volume: 244, Issue:1
Glyphosate is an inhibitor of plant cytochrome P450: functional expression of Thlaspi arvensae cytochrome P45071B1/reductase fusion protein in Escherichia coli.
AID1103051Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.45 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082940Post-emergence herbicidal activity against Ipomoea nil (Japanese morning glory) assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1081430Herbicidal activity against Conyza bonariensis (hairy fleabane) at rosette stage (BBHC14 to 15) assessed as growth inhibition measured after 21 days2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1091007Induction of shikimate accumulation in Senna obtusifolia (sicklepod) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 348 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081419Drug absorption in Conyza canadensis (horseweed) assessed as translocation in treated leaf at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1091002Induction of shikimate accumulation in Conyza canadensis (horseweed) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 251 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091026Drug level in Sesbania herbacea assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082951Post-emergence herbicidal activity against Amaranthus retroflexus assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1082289Toxicity in young Olea europaea (olive) plants assessed as reduction in non-photochemical quenching photosystem II at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103050Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.84 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082292Toxicity in young Olea europaea (olive) plants assessed as reduction in quantum efficiency of photosystem II at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1091057Growth inhibition of non glyphosate-resistant Zea mays (maize) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102994Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.84 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1091011Ratio of compound to AMPA level in Conyza canadensis (horseweed) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082553Herbicidal activity against Digitaria sanguinalis (hairy crabgrass) assessed as growth inhibition at 1 kg/ha postemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID640436Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells using PEP as substrate after 10 to 15 mins by Michaelis-Menten equation2012Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
Synthesis and evaluation of tetrahedral intermediate mimic inhibitors of 3-deoxy-d-manno-octulosonate 8-phosphate synthase.
AID1103009Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 0.84 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082552Herbicidal activity against Amaranthus retroflexus assessed as growth inhibition at 1 kg/ha preemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1091037Drug level in Pueraria montana var. lobata ( kudzu) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103011Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 9 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091016Ratio of compound to AMPA level in non glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082283Toxicity in young Olea europaea (olive) plants assessed as reduction in photosynthetic rate at 3 kg/ha measured 60 days post dose in presence of oil Olea europaea (olive)-mill waste2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1102975Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 9 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103039Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 9 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091055Growth inhibition of Vigna unguiculata (cowpea) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081425Drug absorption in Conyza sumatrensis ( tall fleabane) at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1103030Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.45 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082276Toxicity in young Olea europaea (olive) plants assessed as reduction in intracellular CO2 level at 3 kg/ha measured 60 days post dose in presence of oil Olea europaea (olive)-mill waste2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1082557Herbicidal activity against Poa annua assessed as growth inhibition at 32 ppm by 96-well plate test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1399320Allelopathic activity against Triticum aestivum assessed as germination rate at 4 ug/ml after 48 hrs (Rvb = 91 +/- 0.42%)2018Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18
Design and synthesis of C
AID1082550Herbicidal activity against Stellaria media assessed as growth inhibition at 1 kg/ha preemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1082556Herbicidal activity against Amaranthus retroflexus assessed as growth inhibition at 1 kg/ha postemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1082935Post-emergence herbicidal activity against Brassica rapa subsp. oleifera assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1102997Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 3.36 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082275Toxicity in young Olea europaea (olive) plants assessed as reduction in intracellular CO2 level at 3 kg/ha measured 60 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1091044Drug level in glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091038Drug level in Desmanthus illinoensis (Illinois bundleflower) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102974Herbicidal activity against Conyza canadensis (horseweed) under greenhouse condition at 0.05 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102472Inhibition of seed germination in Lactuca sativa (lettuce) at 10'-4 to 10'-9 M after 5 days relative to control2003Journal of agricultural and food chemistry, Oct-08, Volume: 51, Issue:21
Lignans and neolignans from Brassica fruticulosa: effects on seed germination and plant growth.
AID1103031Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 9 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082939Post-emergence herbicidal activity against Raphanus sativus (radish) assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1082288Toxicity in young Olea europaea (olive) plants assessed as induction of chronic photoinhibition of photosystem II at 3 kg/ha measured 60 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1102990Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 3.36 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1081427Herbicidal activity against Conyza bonariensis (hairy fleabane) at bolting stage (BBHC32) assessed as growth inhibition measured after 21 days2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1082282Toxicity in young Olea europaea (olive) plants assessed as reduction in stomatal conductance at 3 kg/ha measured 60 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1102984Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 3.36 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102972Herbicidal activity against Conyza canadensis (horseweed) under greenhouse condition at 0.05 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082558Herbicidal activity against Arabidopsis thaliana assessed as growth inhibition at 10 ppm by 96-well plate test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1103005Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 3.36 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091019Drug level in non glyphosate-resistant Zea mays (maize) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091053Growth inhibition of Senna occidentalis (coffee senna) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091050Growth inhibition of Pueraria montana var. lobata ( kudzu) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1090999Induction of shikimate accumulation in non glyphosate-resistant Zea mays (maize) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 161 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091027Drug level in Senna obtusifolia (sicklepod) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102976Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 9 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091004Induction of shikimate accumulation in Desmanthus illinoensis (Illinois bundleflower) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 21 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103008Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 1.25 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103016Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.84 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102993Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.25 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091042Drug level in Vigna unguiculata (cowpea) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082949Post-emergence herbicidal activity against Raphanus sativus (radish) assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1082941Post-emergence herbicidal activity against Brassica rapa subsp. chinensis assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1399319Allelopathic activity against Raphanus sativus assessed as germination rate at 4 ug/ml after 48 hrs (Rvb = 92 +/- 0.47%)2018Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18
Design and synthesis of C
AID1102468Effect on root elongation in Lactuca sativa (lettuce) at 10'-4 to 10'-9 M after 5 days relative to control2003Journal of agricultural and food chemistry, Oct-08, Volume: 51, Issue:21
Lignans and neolignans from Brassica fruticulosa: effects on seed germination and plant growth.
AID1103029Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.84 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082945Post-emergence herbicidal activity against Brassica rapa subsp. oleifera assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1081428Herbicidal activity against Conyza bonariensis (hairy fleabane) at flowering stage (BBHC55) assessed as growth inhibition measured after 21 days2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1102986Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.68 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082946Post-emergence herbicidal activity against Brassica oleracea assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1103056Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.25 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091000Induction of shikimate accumulation in glyphosate-resistant Zea mays (maize) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 241 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102991Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 2.52 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103057Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.84 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091005Induction of shikimate accumulation in Senna occidentalis (coffee senna) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 277 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1081429Herbicidal activity against Conyza canadensis (horseweed) at rosette stage (BBHC14 to 15) assessed as growth inhibition measured after 21 days2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1091030Drug level in non glyphosate-resistant Glycine max (soybean) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103036Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 1.25 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082286Toxicity in young Olea europaea (olive) plants assessed as reduction in photosynthetic rate at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1081431Herbicidal activity against Conyza sumatrensis ( tall fleabane) at rosette stage (BBHC14 to 15) assessed as growth inhibition measured after 21 days2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1110710Post-emergence herbicidal activity against Digitaria sanguinalis (hairy crabgrass) assessed as reduction of seed germination at 1.22 ppm after 5 to 25 days by pot test2000Farmaco (Societa chimica italiana : 1989), May, Volume: 55, Issue:5
Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
AID1090679Inhibition of Spinacia oleracea (spinach) glutamine synthetase activity2007Journal of agricultural and food chemistry, May-30, Volume: 55, Issue:11
Plant P5C reductase as a new target for aminomethylenebisphosphonates.
AID1091031Drug level in glyphosate-resistant Glycine max (soybean) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102973Herbicidal activity against Conyza canadensis (horseweed) under greenhouse condition at 0.05 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102999Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.68 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102971Herbicidal activity against Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 0.05 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091056Growth inhibition of Abutilon theophrasti (velvetleaf) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103045Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.45 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1081414Drug absorption in Conyza bonariensis (hairy fleabane) assessed as translocation in root at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1081420Drug absorption in Conyza bonariensis (hairy fleabane) assessed as translocation in treated leaf at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1103025Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 3.36 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102988Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.84 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091021Drug level in Conyza canadensis (horseweed) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102987Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.25 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082549Herbicidal activity against Digitaria sanguinalis (hairy crabgrass) assessed as growth inhibition at 1 kg/ha preemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1091020Drug level in Lolium multiflorum (Italian ryegrass) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091008Induction of shikimate accumulation in glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 65 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082952Post-emergence herbicidal activity against Brassica rapa subsp. chinensis assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1081417Drug absorption in Conyza canadensis (horseweed) assessed as translocation in rest of plant at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1081423Drug absorption in Conyza bonariensis (hairy fleabane) at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1091013Ratio of compound to AMPA level in Senna occidentalis (coffee senna) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103047Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 2.52 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082278Toxicity in young Olea europaea (olive) plants assessed as reduction in intracellular CO2 level at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103023Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.45 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091006Induction of shikimate accumulation in Sesbania herbacea at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 266 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103028Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.25 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103001Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.84 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091018Ratio of compound to AMPA level in glyphosate-resistant Glycine max (soybean) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103033Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 3.36 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091046Growth inhibition of glyphosate-resistant Zea mays (maize) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082281Toxicity in young Olea europaea (olive) plants assessed as reduction in stomatal conductance at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103048Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.68 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1110708Post-emergence herbicidal activity against Cynodon dactylon assessed as reduction of seed germination at 1.22 ppm after 5 to 25 days by pot test2000Farmaco (Societa chimica italiana : 1989), May, Volume: 55, Issue:5
Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
AID1091032Drug level in non glyphosate-resistant Zea mays (maize) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103010Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 0.45 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091034Drug level in glyphosate-resistant Zea mays (maize) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082950Post-emergence herbicidal activity against Ipomoea nil (Japanese morning glory) assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1102978Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 2.52 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082934Post-emergence herbicidal activity against Chenopodium album assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1103026Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 2.52 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103020Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.68 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103019Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 2.52 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103032Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 9 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091029Drug level in Vigna unguiculata (cowpea) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091024Drug level in Pueraria montana var. lobata ( kudzu) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103041Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 2.52 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102996Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 9 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091049Growth inhibition of glyphosate-resistant Glycine max (soybean) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082936Post-emergence herbicidal activity against Brassica oleracea assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1102985Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 2.52 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102979Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 1.68 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103049Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.25 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103015Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.25 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082947Post-emergence herbicidal activity against Monochoria vaginalis assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1081413Drug absorption in Conyza canadensis (horseweed) assessed as translocation in root at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1091045Growth inhibition of Lolium multiflorum (Italian ryegrass) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102998Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 2.52 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091051Growth inhibition of Desmanthus illinoensis (Illinois bundleflower) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082555Herbicidal activity against Lolium perenne (perennial ryegrass) assessed as growth inhibition at 1 kg/ha postemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1091036Drug level in Conyza canadensis (horseweed) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103006Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition assessed as decrease in fresh weight at 2.52 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091023Drug level in Abutilon theophrasti (velvetleaf) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1082943Post-emergence herbicidal activity against Brassica juncea assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1091012Ratio of compound to AMPA level in Pueraria montana var. lobata ( kudzu) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091028Drug level in Senna occidentalis (coffee senna) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091003Induction of shikimate accumulation in Pueraria montana var. lobata ( kudzu) at growth inhibition I50 level rate measured 7 days post treatment (Rvb = 188 ug/g tissue)2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091017Ratio of compound to AMPA level in Vigna unguiculata (cowpea) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103055Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.68 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103021Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.25 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091039Drug level in Sesbania herbacea at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103058Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.45 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102992Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 1.68 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091041Drug level in Senna obtusifolia (sicklepod) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1110707Post-emergence herbicidal activity against Euphorbia hirta assessed as reduction of seed germination at 1.22 ppm after 5 to 25 days by pot test2000Farmaco (Societa chimica italiana : 1989), May, Volume: 55, Issue:5
Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
AID1091048Growth inhibition of non glyphosate-resistant Glycine max (soybean) measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1110706Post-emergence herbicidal activity against Parthenium hysterophorus assessed as reduction of seed germination at 1.22 ppm after 5 to 25 days by pot test2000Farmaco (Societa chimica italiana : 1989), May, Volume: 55, Issue:5
Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
AID1082284Toxicity in young Olea europaea (olive) plants assessed as reduction in photosynthetic rate at 3 kg/ha measured 15 days post dose in presence of oil Olea europaea (olive)-mill waste2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103013Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 2.52 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091025Drug level in Desmanthus illinoensis (Illinois bundleflower) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102980Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 1.25 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103012Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 3.36 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103014Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 1.68 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082285Toxicity in young Olea europaea (olive) plants assessed as reduction in photosynthetic rate at 3 kg/ha measured 60 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103040Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 3.36 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103044Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 0.84 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103042Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 1.68 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091014Ratio of compound to AMPA level in Desmanthus illinoensis (Illinois bundleflower) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1102995Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 0.45 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082944Post-emergence herbicidal activity against Chenopodium album assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1105558Inhibition of Thlaspi arvense CPR-fused CYP71B1 expressed in Escherichia coli DH5alpha assessed as conversion of benzo(a)pyrene to 3-hydroxybenzo(a)pyrene at 30 uM1998Biochemical and biophysical research communications, Mar-06, Volume: 244, Issue:1
Glyphosate is an inhibitor of plant cytochrome P450: functional expression of Thlaspi arvensae cytochrome P45071B1/reductase fusion protein in Escherichia coli.
AID1091033Drug level in Lolium multiflorum (Italian ryegrass) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1091035Drug level in Abutilon theophrasti (velvetleaf) at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103053Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 2.52 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1081421Drug absorption in Conyza canadensis (horseweed) at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1102983Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition at 9 kg ae/ha measured 21 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1102977Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 2 under greenhouse condition assessed as decrease in fresh weight at 3.36 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082554Herbicidal activity against Stellaria media assessed as growth inhibition at 1 kg/ha postemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1103003Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 9 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1090678Inhibition of glutamine synthetase in Nicotiana tabacum (tobacco) cells2007Journal of agricultural and food chemistry, May-30, Volume: 55, Issue:11
Plant P5C reductase as a new target for aminomethylenebisphosphonates.
AID1091022Drug level in glyphosate-resistant Zea mays (maize) assessed as AMPA level at growth inhibition I50 level rate measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1103037Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition assessed as decrease in fresh weight at 0.84 kg ae/ha measured 21 days post treatment relative to untreated control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1082948Post-emergence herbicidal activity against Ammannia baccifera assessed as inhibition at 150 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1082933Post-emergence herbicidal activity against Brassica juncea assessed as inhibition at 75 g/hectare by green house assay2012Journal of agricultural and food chemistry, Aug-08, Volume: 60, Issue:31
Synthesis and herbicidal activity of 2-(substituted phenoxyacetoxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one.
AID1103046Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 3.36 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1091052Growth inhibition of Sesbania herbacea measured 7 days post treatment2008Journal of agricultural and food chemistry, Mar-26, Volume: 56, Issue:6
Aminomethylphosphonic acid accumulation in plant species treated with glyphosate.
AID1105560Binding affinity to Thlaspi arvense CPR-fused CYP71B1 expressed in Escherichia coli DH5alpha1998Biochemical and biophysical research communications, Mar-06, Volume: 244, Issue:1
Glyphosate is an inhibitor of plant cytochrome P450: functional expression of Thlaspi arvensae cytochrome P45071B1/reductase fusion protein in Escherichia coli.
AID1081418Drug absorption in Conyza sumatrensis (tall fleabane) assessed as translocation in rest of plant at 1 g/ha measured after 96 hr by liquid scintillation spectrometry2010Journal of agricultural and food chemistry, Apr-14, Volume: 58, Issue:7
Differential susceptibility to glyphosate among the Conyza weed species in Spain.
AID1082551Herbicidal activity against Lolium perenne (perennial ryegrass) assessed as growth inhibition at 1 kg/ha preemergence treatment by glasshouse test2011Journal of agricultural and food chemistry, Nov-09, Volume: 59, Issue:21
Design, synthesis, and biological activities of arylmethylamine substituted chlorotriazine and methylthiotriazine compounds.
AID1082295Toxicity in young Olea europaea (olive) plants assessed as effect on maximum quantum efficiency of photosystem II at 3 kg/ha measured at midday 24 hr post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1103022Herbicidal activity against compound-resistant Conyza canadensis (horseweed) isolate 1 under greenhouse condition at 0.84 kg ae/ha measured 14 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID1103052Herbicidal activity against compound-sensitive Conyza canadensis (horseweed) under greenhouse condition at 9 kg ae/ha measured 7 days post treatment relative to control2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Response of selected horseweed (Conyza canadensis (L.) Cronq.) populations to glyphosate.
AID640437Competitive inhibition of Acidithiobacillus ferrooxidans KDO8P synthase using PEP as substrate after 10 to 15 mins by Michaelis-Menten equation2012Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
Synthesis and evaluation of tetrahedral intermediate mimic inhibitors of 3-deoxy-d-manno-octulosonate 8-phosphate synthase.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1082294Toxicity in young Olea europaea (olive) plants assessed as effect on maximum quantum efficiency of photosystem II at 3 kg/ha measured 15 days post dose2011Journal of agricultural and food chemistry, May-25, Volume: 59, Issue:10
Effect of the herbicides terbuthylazine and glyphosate on photosystem II photochemistry of young olive (Olea europaea) plants.
AID1224817Assays to identify small molecules inhibitory for eIF4E expression2015Chemistry & biology, Jul-23, Volume: 22, Issue:7
Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.
AID977608Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB2006Proceedings of the National Academy of Sciences of the United States of America, Aug-29, Volume: 103, Issue:35
Molecular basis for the herbicide resistance of Roundup Ready crops.
AID1811Experimentally measured binding affinity data derived from PDB2006Proceedings of the National Academy of Sciences of the United States of America, Aug-29, Volume: 103, Issue:35
Molecular basis for the herbicide resistance of Roundup Ready crops.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4,863)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990277 (5.70)18.7374
1990's304 (6.25)18.2507
2000's883 (18.16)29.6817
2010's2122 (43.64)24.3611
2020's1277 (26.26)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 63.65

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index63.65 (24.57)
Research Supply Index8.56 (2.92)
Research Growth Index5.11 (4.65)
Search Engine Demand Index220.14 (26.88)
Search Engine Supply Index3.88 (0.95)

This Compound (63.65)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials108 (2.12%)5.53%
Reviews321 (6.29%)6.00%
Case Studies285 (5.59%)4.05%
Observational33 (0.65%)0.25%
Other4,353 (85.35%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]