| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Anemia, Fanconi
[description not available] | 0 | 2.13 | 1 | 0 |
Fanconi Anemia
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004) | 0 | 2.13 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.01 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.01 | 1 | 0 |
Menstruation, Painful
[description not available] | 0 | 1.93 | 1 | 0 |
Premenstrual Tension
A term used to describe the psychological aspects of PREMENSTRUAL SYNDROME, such as the indescribable tension, depression, hostility, and increased seizure activity in women with seizure disorder. | 0 | 1.93 | 1 | 0 |
Dysmenorrhea
Painful menstruation. | 0 | 1.93 | 1 | 0 |
Premenstrual Syndrome
A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses. | 0 | 1.93 | 1 | 0 |
Cataract, Membranous
[description not available] | 0 | 1.93 | 1 | 0 |
Hypertelorism
Abnormal increase in the interorbital distance due to overdevelopment of the lesser wings of the sphenoid. | 0 | 1.93 | 1 | 0 |
Cataract
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 1.93 | 1 | 0 |
Female Genital Diseases
[description not available] | 0 | 3.31 | 7 | 0 |
Genital Diseases, Female
Pathological processes involving the female reproductive tract (GENITALIA, FEMALE). | 0 | 3.31 | 7 | 0 |
Emaciation
Clinical manifestation of excessive LEANNESS usually caused by disease or a lack of nutrition (MALNUTRITION). | 0 | 1.93 | 1 | 0 |
Leanness
[description not available] | 0 | 2.33 | 2 | 0 |
Menopause
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. | 0 | 2.62 | 3 | 0 |
Polyarthritis
[description not available] | 0 | 2.34 | 2 | 0 |
Rheumatoid Arthritis
[description not available] | 0 | 1.93 | 1 | 0 |
Breast Cancer
[description not available] | 0 | 3.03 | 5 | 0 |
Arthritis
Acute or chronic inflammation of JOINTS. | 0 | 2.34 | 2 | 0 |
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 1.93 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 3.03 | 5 | 0 |
Adrenal Cortex Diseases
Pathological processes of the ADRENAL CORTEX. | 0 | 1.93 | 1 | 0 |
Atrophy
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 1.93 | 1 | 0 |
Complications, Pregnancy
[description not available] | 0 | 1.93 | 1 | 0 |
Ambiguous Genitalia
[description not available] | 0 | 2.62 | 3 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 2.63 | 3 | 0 |
Disorders of Sex Development
In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included. | 0 | 2.62 | 3 | 0 |
Blood Pressure, High
[description not available] | 0 | 3.19 | 6 | 0 |
Nephrosclerosis
Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA. | 0 | 2.33 | 2 | 0 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 3.19 | 6 | 0 |
Nephritis
Inflammation of any part of the KIDNEY. | 0 | 1.93 | 1 | 0 |
Cushing's Syndrome
[description not available] | 0 | 1.93 | 1 | 0 |
Cushing Syndrome
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent. | 0 | 1.93 | 1 | 0 |
Symptom Cluster
[description not available] | 0 | 1.93 | 1 | 0 |
Syndrome
A characteristic symptom complex. | 0 | 1.93 | 1 | 0 |
Ankylosis
Fixation and immobility of a joint. | 0 | 1.93 | 1 | 0 |
Ankylosing Spondylarthritis
[description not available] | 0 | 1.93 | 1 | 0 |
Spondylitis
Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions. | 0 | 1.93 | 1 | 0 |
Spondylitis, Ankylosing
A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions. | 0 | 1.93 | 1 | 0 |
Hypomenorrhea
[description not available] | 0 | 1.93 | 1 | 0 |
Disease
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. | 0 | 2.33 | 2 | 0 |
Cachexia
General ill health, malnutrition, and weight loss, usually associated with chronic disease. | 0 | 1.93 | 1 | 0 |
Benign Neoplasms
[description not available] | 0 | 3.31 | 7 | 0 |
Cancer of Ovary
[description not available] | 0 | 1.93 | 1 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 3.31 | 7 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 1.93 | 1 | 0 |
Carditis
[description not available] | 0 | 1.93 | 1 | 0 |
Myocarditis
Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies. | 0 | 1.93 | 1 | 0 |
Congenital Myotonic Dystrophy
[description not available] | 0 | 1.93 | 1 | 0 |
Myotonic Dystrophy
Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2. | 0 | 1.93 | 1 | 0 |
Adenohypophyseal Diseases
[description not available] | 0 | 1.93 | 1 | 0 |
Pituitary Diseases
Disorders involving either the ADENOHYPOPHYSIS or the NEUROHYPOPHYSIS. These diseases usually manifest as hypersecretion or hyposecretion of PITUITARY HORMONES. Neoplastic pituitary masses can also cause compression of the OPTIC CHIASM and other adjacent structures. | 0 | 1.93 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 3.18 | 6 | 0 |
Koch's Disease
[description not available] | 0 | 2.84 | 4 | 0 |
Pulmonary Consumption
[description not available] | 0 | 2.84 | 4 | 0 |
Tuberculosis
Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS. | 0 | 2.84 | 4 | 0 |
Tuberculosis, Pulmonary
MYCOBACTERIUM infections of the lung. | 0 | 2.84 | 4 | 0 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 1.93 | 1 | 0 |
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues. | 0 | 1.93 | 1 | 0 |
Cancer of the Uterus
[description not available] | 0 | 4.57 | 6 | 1 |
Uterine Neoplasms
Tumors or cancer of the UTERUS. | 0 | 4.57 | 6 | 1 |
Breast Pain
[description not available] | 0 | 2.33 | 2 | 0 |
Breast Diseases
Pathological processes of the BREAST. | 0 | 2.63 | 3 | 0 |
Mastodynia
Pain in the breast generally classified as cyclical (associated with menstrual periods), or noncyclical, i.e. originating from the breast or nearby muscles or joints, ranging from minor discomfort to severely incapacitating. | 0 | 2.33 | 2 | 0 |
Infant Malnutrition
Malnutrition, occurring in infants ages 1 month to 24 months, which is due to insufficient intake of food, dietary nutrients, or a pathophysiologic condition which prevents the absorption and utilization of food. Growth and development are markedly affected. | 0 | 1.93 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.84 | 4 | 0 |
Bone Fractures
[description not available] | 0 | 1.93 | 1 | 0 |
Fractures, Bone
Breaks in bones. | 0 | 1.93 | 1 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 1.93 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 1.93 | 1 | 0 |
Liver Dysfunction
[description not available] | 0 | 1.93 | 1 | 0 |
Liver Diseases
Pathological processes of the LIVER. | 0 | 1.93 | 1 | 0 |
Adverse Drug Event
[description not available] | 0 | 2.34 | 2 | 0 |
Drug-Related Side Effects and Adverse Reactions
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. | 0 | 2.34 | 2 | 0 |
Muscular Dystrophy
[description not available] | 0 | 3.55 | 3 | 0 |
Muscular Dystrophies
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS. | 0 | 3.55 | 3 | 0 |
Arthritis, Juvenile Chronic
[description not available] | 0 | 1.93 | 1 | 0 |
Dermatomyositis, Adult Type
[description not available] | 0 | 1.93 | 1 | 0 |
Acute Rheumatic Fever
[description not available] | 0 | 1.93 | 1 | 0 |
Rheumatism
[description not available] | 0 | 1.93 | 1 | 0 |
Arthritis, Juvenile
Arthritis in children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent. | 0 | 1.93 | 1 | 0 |
Dermatomyositis
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) | 0 | 1.93 | 1 | 0 |
Rheumatic Diseases
Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement. | 0 | 1.93 | 1 | 0 |
Animal Mammary Carcinoma
[description not available] | 0 | 1.94 | 1 | 0 |
Experimental Mammary Neoplasms
[description not available] | 0 | 1.94 | 1 | 0 |
Complications of Diabetes Mellitus
[description not available] | 0 | 1.93 | 1 | 0 |
Diabetic Retinopathy
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 1.93 | 1 | 0 |
Retinal Diseases
Diseases involving the RETINA. | 0 | 1.93 | 1 | 0 |
Eunuchism
The state of being a eunuch, a male without TESTES or whose testes failed to develop. It is characterized by the lack of mature male GERM CELLS and TESTICULAR HORMONES. | 0 | 1.93 | 1 | 0 |
Cancer, Second Primary
[description not available] | 0 | 1.92 | 1 | 0 |
Chronic Illness
[description not available] | 0 | 1.96 | 1 | 0 |
Addison's Disease
[description not available] | 0 | 1.96 | 1 | 0 |
Acute Edematous Pancreatitis
[description not available] | 0 | 1.96 | 1 | 0 |
Addison Disease
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES. | 0 | 1.96 | 1 | 0 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 1.96 | 1 | 0 |
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 1.96 | 1 | 0 |
Muscular Dystrophy, Animal
MUSCULAR DYSTROPHY that occurs in VERTEBRATE animals. | 0 | 2.88 | 1 | 0 |
Aggression
Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. | 0 | 1.96 | 1 | 0 |
Canine Diseases
[description not available] | 0 | 1.96 | 1 | 0 |
Galactorrhea
Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA. | 0 | 1.96 | 1 | 0 |
Ache
[description not available] | 0 | 1.95 | 1 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 1.95 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2 | 1 | 0 |
Coronary Heart Disease
[description not available] | 0 | 3.33 | 1 | 1 |
Coagulation, Disseminated Intravascular
[description not available] | 0 | 3.33 | 1 | 1 |
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 3.33 | 1 | 1 |
Disseminated Intravascular Coagulation
A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS. | 0 | 3.33 | 1 | 1 |
Fibroid
[description not available] | 0 | 3.34 | 1 | 1 |
Heavy Menstrual Bleeding
[description not available] | 0 | 3.34 | 1 | 1 |
Leiomyoma
A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues. | 0 | 3.34 | 1 | 1 |
Menorrhagia
Excessive uterine bleeding during MENSTRUATION. | 0 | 3.34 | 1 | 1 |