Page last updated: 2024-08-07 12:49:31

Beta-lactamase

A protein that is a translation product of any of the plasmid-encoded copies of the blaZ gene in Staphylococcus aureus. [PRO:DAN, UniProtKB:P00807]

Synonyms

EC 3.5.2.6;
Penicillinase

Research

Bioassay Publications (10)

TimeframeStudies on this Protein(%)All Drugs %
pre-19902 (20.00)18.7374
1990's2 (20.00)18.2507
2000's6 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (13)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
boric acidStaphylococcus aureusKi2,150.000012
3-aminobenzeneboronic acidStaphylococcus aureusKi7.300011
tazobactamStaphylococcus aureusIC500.500011
sulbactamStaphylococcus aureusIC506.500011
methaneboronic acidStaphylococcus aureusKi1,750.000012
clavulanic acidStaphylococcus aureusIC500.080011
tazobactam sodiumStaphylococcus aureusIC5010.071266

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
cephaloridineStaphylococcus aureusKm110.000011
penicillin gStaphylococcus aureusKm7.700022
cephalothinStaphylococcus aureusKm1.000011
cefepimeStaphylococcus aureusKm61.000011
ceftazidimeStaphylococcus aureusKm29.000011
ceftobiproleStaphylococcus aureusKm78.000011