hydrochlorothiazide has been researched along with Sensitivity and Specificity in 52 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to determine whether hydrochlorothiazide (HCTZ) could improve radioiodine uptake in low-uptake hyperthyroid patients." | 9.10 | Enhancement of radioiodine uptake in hyperthyroidism with hydrochlorothiazide: a prospective randomised control study. ( Tepmongkol, S, 2002) |
| "The aim of this study was to determine whether hydrochlorothiazide (HCTZ) could improve radioiodine uptake in low-uptake hyperthyroid patients." | 5.10 | Enhancement of radioiodine uptake in hyperthyroidism with hydrochlorothiazide: a prospective randomised control study. ( Tepmongkol, S, 2002) |
| " Statistical comparison showed that the test and reference products were bioequivalent in terms of both the rate and extent of bioavailability of both active ingredients." | 2.76 | Bioequivalence evaluation of a triamterene-hydrochlorothiazide generic product: a new bioequivalence index for fixed-dose combinations. ( Azimi, K; Hamidi, M; Shahbazi, MA, 2011) |
| " Based on the 90% confidence interval of the individual ratios for Cmax and AUC0-inf, it was concluded that the test formulation is bioequivalent to the reference Hyzaar formulation with respect to the rate and extent of absorption of both LOS and HCTZ." | 2.74 | Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics. ( Andraus, MH; Azevedo, CP; Borges, BC; Borges, NC; Moreira, RF; Moreno, RA; Salvadori, MC, 2009) |
| " Night-time dosing of thiazides may be particularly beneficial in patients with modest glucocorticoid excess." | 1.43 | Glucocorticoids Induce Nondipping Blood Pressure by Activating the Thiazide-Sensitive Cotransporter. ( Al-Dujaili, EA; Bailey, MA; Dear, JW; Dhaun, N; Flatman, PW; Howarth, AR; Hunter, RW; Ivy, JR; Oosthuyzen, W; Peltz, TS; Webb, DJ, 2016) |
| "Accurate, sensitive and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC), high-performance thin-layer chromatography (HPTLC) and ultraviolet (UV) spectrophopometric methods were developed for the concurrent estimation of amlodipine besylate (AMLO), hydrochlorothiazide (HCTZ) and valsartan (VALS) in bulk and combined tablet dosage forms." | 1.40 | Concurrent estimation of amlodipine besylate, hydrochlorothiazide and valsartan by RP-HPLC, HPTLC and UV-spectrophotometry. ( Kothari, C; Mehta, P; Sharma, M; Sherikar, O, 2014) |
| "A simple, specific, accurate and precise stability-indicating reversed-phase high-performance liquid chromatographic method was developed for simultaneous estimation of olmesartan medoxomile (OLME), amlodipine besylate (AMLO) and hydrochlorothiazide (HCTZ) in tablet dosage form." | 1.38 | Stability-indicating method for simultaneous estimation of olmesartan medoxomile, amlodipine besylate and hydrochlorothiazide by RP-HPLC in tablet dosage form. ( Chaudhari, AJ; Gorle, AP; Jain, PS; Patel, MK; Surana, SJ, 2012) |
| "A simple, precise and stability-indicating HPLC method was developed and validated for the simultaneous determination of bisoprolol fumarate and hydrochlorothiazide in pharmaceutical dosage form." | 1.36 | RP-HPLC method for simultaneous estimation of bisoprolol fumarate and hydrochlorothiazide in tablet formulation. ( Bhoir, SI; Bindu, KS; Das, C; Joshi, SJ; Karbhari, PA, 2010) |
| "Methylparaben was used as internal standard." | 1.36 | Stability indicating LC method for simultaneous determination of irbesartan and hydrochlorothiazide in pharmaceutical preparations. ( Patil, KR; Rane, VP; Sangshetti, JN; Shinde, DB; Yeole, RD, 2010) |
| "Chlorothiazide was determined to be a minor metabolite of altizide and hydrochlorothiazide and could be detected up to 120 h." | 1.35 | Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis. ( Delbeke, FT; Deventer, K; Pozo, OJ; Van Eenoo, P, 2009) |
| "Although the diagnosis of Gitelman syndrome (GS) and Bartter syndrome (BS) is now feasible by genetic analysis, implementation of genetic testing for these disorders is still hampered by several difficulties, including large gene dimensions, lack of hot-spot mutations, heavy workup time, and costs." | 1.34 | A thiazide test for the diagnosis of renal tubular hypokalemic disorders. ( Bettinelli, A; Bianchetti, MG; Borsa, N; Casari, G; Colussi, G; De Ferrari, ME; Mattiello, C; Syrén, ML; Tedeschi, S, 2007) |
| " The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetic, bioavailability or bioequivalence studies." | 1.33 | Sensitive liquid chromatography-tandem mass spectrometry method for quantification of hydrochlorothiazide in human plasma. ( Koteshwara, M; Manoj, S; Ramakrishna, NV; Varma, DP; Vishwottam, KN; Wishu, S, 2005) |
| "Four sensitive methods are described for the direct determination of telmisartan (TELM) and hydrochlorothiazide (HCT) in combined dosage forms without prior separation." | 1.33 | Application of first-derivative, ratio derivative spectrophotometry, TLC-densitometry and spectrofluorimetry for the simultaneous determination of telmisartan and hydrochlorothiazide in pharmaceutical dosage forms and plasma. ( Abbas, SS; Bebawy, LI; Fattah, LA; Refaat, HH, 2005) |
| " The drug's effect as well as adverse effects should be actively sought, and dosage alterations made in order to enhance the drug's effect." | 1.32 | Introduction to monitoring. What is what you prescribed actually doing? ( George, A; Shakib, S, 2003) |
| " It is considered one of the most important quality control tests performed on pharmaceutical dosage forms, and validation of dissolution methods is an important part of good manufacturing practices (GMP)." | 1.31 | Validation of tablet dissolution method by high-performance liquid chromatography. ( Dluzneski, PR; Guo, JH; Harcum, WW; Skinner, GW; Trumbull, DE, 2000) |
| "A simple, rapid and sensitive HPLC method has been developed for the simultaneous determination of ramipril and hydrochlorothiazide in their dosage forms." | 1.31 | A stability-indicating LC method for the simultaneous determination of ramipril and hydrochlorothiazide in dosage forms. ( Abounassif, MA; Al-Zaagi, IA; Belal, F; Gadkariem, EA, 2001) |
| "A micro-bore liquid chromatographic method was developed for the simultaneous determination of benazepril hydrochloride and hydrochlorothiazide in pharmaceutical dosage forms." | 1.30 | Simultaneous determination of benazepril hydrochloride and hydrochlorothiazide by micro-bore liquid chromatography. ( Panderi, IE; Parissi-Poulou, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (7.69) | 18.2507 |
| 2000's | 29 (55.77) | 29.6817 |
| 2010's | 19 (36.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Šljivic, J | 1 |
| Protic, A | 1 |
| Otaševic, B | 1 |
| Golubovic, J | 1 |
| Zecevic, M | 2 |
| Krmar, J | 1 |
| Qiu, X | 1 |
| Wang, Z | 1 |
| Wang, B | 1 |
| Zhan, H | 1 |
| Pan, X | 1 |
| Xu, RA | 1 |
| Koyuturk, S | 1 |
| Can, NO | 1 |
| Atkosar, Z | 1 |
| Arli, G | 1 |
| Mannemala, SS | 1 |
| Nagarajan, JS | 1 |
| Patel, JR | 1 |
| Pethani, TM | 1 |
| Vachhani, AN | 1 |
| Sheth, NR | 1 |
| Dudhrejiya, AV | 1 |
| Jiang, L | 1 |
| Peng, X | 1 |
| Ma, J | 1 |
| Yuan, T | 2 |
| Qin, Y | 1 |
| Wang, O | 2 |
| Wang, H | 1 |
| Wang, Y | 3 |
| Chen, G | 1 |
| Yue, C | 2 |
| Li, C | 1 |
| Nie, M | 1 |
| Xing, X | 1 |
| Li, X | 1 |
| Lee, X | 1 |
| Chen, L | 1 |
| Machini, WB | 1 |
| David-Parra, DN | 1 |
| Teixeira, MF | 1 |
| Ivy, JR | 1 |
| Oosthuyzen, W | 1 |
| Peltz, TS | 1 |
| Howarth, AR | 1 |
| Hunter, RW | 1 |
| Dhaun, N | 1 |
| Al-Dujaili, EA | 1 |
| Webb, DJ | 1 |
| Dear, JW | 1 |
| Flatman, PW | 1 |
| Bailey, MA | 1 |
| Peng, XY | 1 |
| Jiang, LP | 1 |
| Zheng, K | 1 |
| Li, NS | 1 |
| Li, W | 1 |
| Tong, AL | 1 |
| Xing, XP | 1 |
| Li, XM | 1 |
| Li, XW | 1 |
| Chen, LM | 1 |
| Vespasiano, CF | 1 |
| Laurito, TL | 1 |
| Iwamoto, RD | 1 |
| Moreno, RA | 2 |
| Mendes, GD | 1 |
| De Nucci, G | 1 |
| Ekman, M | 1 |
| Bienfait-Beuzon, C | 1 |
| Jackson, J | 1 |
| Parekh, SA | 1 |
| Pudage, A | 1 |
| Joshi, SS | 1 |
| Vaidya, VV | 1 |
| Gomes, NA | 1 |
| Kamat, SS | 1 |
| Shaikh, S | 1 |
| Thusleem, OA | 1 |
| Muneera, MS | 1 |
| Akmal, J | 1 |
| Kondaguli, AV | 1 |
| Ruckmani, K | 1 |
| Yan, T | 1 |
| Li, H | 2 |
| Deng, L | 1 |
| Guo, Y | 1 |
| Yu, W | 1 |
| Fawcett, JP | 1 |
| Zhang, D | 1 |
| Cui, Y | 1 |
| Gu, J | 2 |
| Deventer, K | 1 |
| Pozo, OJ | 1 |
| Van Eenoo, P | 1 |
| Delbeke, FT | 1 |
| Salvadori, MC | 1 |
| Moreira, RF | 1 |
| Borges, BC | 1 |
| Andraus, MH | 1 |
| Azevedo, CP | 1 |
| Borges, NC | 1 |
| Joshi, SJ | 1 |
| Karbhari, PA | 1 |
| Bhoir, SI | 1 |
| Bindu, KS | 1 |
| Das, C | 1 |
| Rajasekhar, D | 1 |
| Kumara, IJ | 1 |
| Venkateswarlu, P | 1 |
| Rane, VP | 1 |
| Patil, KR | 1 |
| Sangshetti, JN | 1 |
| Yeole, RD | 1 |
| Shinde, DB | 1 |
| Hamidi, M | 1 |
| Shahbazi, MA | 1 |
| Azimi, K | 1 |
| Hegazy, MA | 1 |
| Metwaly, FH | 1 |
| Abdelkawy, M | 1 |
| Abdelwahab, NS | 1 |
| Zhang, WT | 1 |
| Li, ST | 1 |
| Li, Y | 1 |
| Sun, CJ | 1 |
| Shang, D | 1 |
| Wang, X | 1 |
| Zhao, X | 1 |
| Huang, F | 1 |
| Tian, G | 1 |
| Lu, W | 1 |
| Zhou, T | 1 |
| Jain, PS | 1 |
| Patel, MK | 1 |
| Gorle, AP | 1 |
| Chaudhari, AJ | 1 |
| Surana, SJ | 1 |
| Maggio, RM | 1 |
| Rivero, MA | 1 |
| Kaufman, TS | 1 |
| Sharma, M | 1 |
| Kothari, C | 1 |
| Sherikar, O | 1 |
| Mehta, P | 1 |
| Tepmongkol, S | 1 |
| Erk, N | 2 |
| Walter, MA | 1 |
| Nitzsche, EU | 1 |
| Müller-Brand, J | 1 |
| Prieto, JA | 1 |
| Jiménez, RM | 1 |
| Alonso, RM | 1 |
| Shakib, S | 1 |
| George, A | 1 |
| Zendelovska, D | 1 |
| Stafilov, T | 1 |
| Milosevski, P | 1 |
| Takubo, T | 1 |
| Okada, H | 1 |
| Ishii, M | 1 |
| Hara, K | 1 |
| Ishii, Y | 1 |
| Varma, MV | 1 |
| Sarkar, M | 1 |
| Kapoor, N | 1 |
| Panchagnula, R | 1 |
| Ramakrishna, NV | 1 |
| Vishwottam, KN | 1 |
| Manoj, S | 1 |
| Koteshwara, M | 1 |
| Wishu, S | 1 |
| Varma, DP | 1 |
| Bebawy, LI | 1 |
| Abbas, SS | 1 |
| Fattah, LA | 1 |
| Refaat, HH | 1 |
| Jain, DS | 1 |
| Subbaiah, G | 1 |
| Sanyal, M | 1 |
| Jain, VK | 1 |
| Shrivastav, P | 1 |
| Kolocouri, F | 1 |
| Dotsikas, Y | 1 |
| Apostolou, C | 1 |
| Kousoulos, C | 1 |
| Loukas, YL | 1 |
| Jiang, Y | 1 |
| Tang, Y | 1 |
| Wang, J | 1 |
| Zhao, L | 1 |
| Liu, F | 1 |
| Xu, Y | 1 |
| Gao, S | 1 |
| Zhang, J | 1 |
| Guo, Q | 1 |
| Colussi, G | 1 |
| Bettinelli, A | 1 |
| Tedeschi, S | 1 |
| De Ferrari, ME | 1 |
| Syrén, ML | 1 |
| Borsa, N | 1 |
| Mattiello, C | 1 |
| Casari, G | 1 |
| Bianchetti, MG | 1 |
| Mahnensmith, RL | 1 |
| Farthing, D | 1 |
| Fakhry, I | 1 |
| Ripley, EB | 1 |
| Sica, D | 1 |
| Chen, YC | 1 |
| Shiea, J | 1 |
| Sunner, J | 1 |
| Panderi, IE | 1 |
| Parissi-Poulou, M | 1 |
| Guo, JH | 1 |
| Harcum, WW | 1 |
| Skinner, GW | 1 |
| Dluzneski, PR | 1 |
| Trumbull, DE | 1 |
| Carlucci, G | 1 |
| Palumbo, G | 1 |
| Mazzeo, P | 1 |
| Quaglia, MG | 1 |
| Belal, F | 1 |
| Al-Zaagi, IA | 1 |
| Gadkariem, EA | 1 |
| Abounassif, MA | 1 |
| Zivanović, L | 1 |
| Agatonovic-Kustrin, S | 1 |
| Minic, D | 1 |
| Schiffrin, EL | 1 |
| Park, JB | 1 |
| Pu, Q | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Randomized, Parallel Design Study Comparing Effectiveness of Losartan vs. Hydrochlorothiazide in Reversing or Preventing the Progression of the Remodeling of Resistance Arteries in Pre-hypertensive Pre-diabetic Subjects[NCT00388388] | Phase 2 | 1 participants (Actual) | Interventional | 2007-03-31 | Terminated (stopped due to Few subjects recruited, sponsor withdrew support.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydrochlorothiazide and Sensitivity and Specificity
| Article | Year |
|---|---|
Diabetic nephropathy: a comprehensive approach.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Clinical Protocols; Clinical Tria | 1993 |
6 trials available for hydrochlorothiazide and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma by ultra high performance liquid chromatography tandem mass spectrometry and its application to a bioequivalence study.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Hydrochlorothi | 2014 |
Bioequivalence study between a fixed-dose single-pill formulation of nebivolol plus hydrochlorothiazide and separate formulations in healthy subjects using high-performance liquid chromatography coupled to tandem mass spectrometry.
Topics: Adult; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug | 2017 |
Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.
Topics: Administration, Oral; Adult; Chlorthalidone; Chromatography, High Pressure Liquid; Cross-Over Studie | 2009 |
Bioequivalence evaluation of a triamterene-hydrochlorothiazide generic product: a new bioequivalence index for fixed-dose combinations.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Area Under Curve; Biological Availability; Chr | 2011 |
Enhancement of radioiodine uptake in hyperthyroidism with hydrochlorothiazide: a prospective randomised control study.
Topics: Adult; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Hydrochlorothiazide; Hy | 2002 |
Effect of crossing over hypertensive patients from a beta-blocker to an angiotensin receptor antagonist on resistance artery structure and on endothelial function.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin Receptor Antagonists; Antihyper | 2002 |
45 other studies available for hydrochlorothiazide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Multicriteria Optimization Methodology in Stability-Indicating Method Development of Cilazapril and Hydrochlorothiazide.
Topics: Chromatography, High Pressure Liquid; Cilazapril; Drug Stability; Hydrochlorothiazide; Linear Models | 2017 |
A novel dilute and shoot HPLC assay method for quantification of irbesartan and hydrochlorothiazide in combination tablets and urine using second generation C18-bonded monolithic silica column with double gradient elution.
Topics: Acetamides; Biphenyl Compounds; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; I | 2014 |
Development and validation of a HPLC-PDA bioanalytical method for the simultaneous estimation of Aliskiren and Amlodipine in human plasma.
Topics: Acetonitriles; Amides; Amlodipine; Chemical Precipitation; Chromatography, High Pressure Liquid; Dru | 2015 |
Development and validation of bioanalytical method for simultaneous estimation of ramipril and hydrochlorothiazide in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Drug Stability; Humans; Hydrochlorothiazide; Linear Models; Ramipril; Reprod | 2014 |
NORMOMAGNESEMIC GITELMAN SYNDROME PATIENTS EXHIBIT A STRONGER REACTION TO THIAZIDE THAN HYPOMAGNESEMIC PATIENTS.
Topics: Adolescent; Adult; Aged; Child; Chlorides; Female; Genotype; Gitelman Syndrome; Humans; Hydrochlorot | 2015 |
Electrochemical investigation of the voltammetric determination of hydrochlorothiazide using a nickel hydroxide modified nickel electrode.
Topics: Conductometry; Diuretics; Doping in Sports; Electrodes; Equipment Design; Equipment Failure Analysis | 2015 |
Glucocorticoids Induce Nondipping Blood Pressure by Activating the Thiazide-Sensitive Cotransporter.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Corticosterone; Disease Mod | 2016 |
Value of Chloride Clearance Test in Differential Diagnosis of Gitelman Syndrome.
Topics: Case-Control Studies; Chlorides; Diagnosis, Differential; Gitelman Syndrome; Humans; Hydrochlorothia | 2016 |
Cost-effectiveness of irbesartan/hydrochlorothiazide in patients with hypertension: an economic evaluation for Sweden.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; | 2008 |
Simultaneous determination of hydrochlorothiazide, quinapril and quinaprilat in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Quinapril; Reproducibility of Res | 2008 |
A simple and rapid high-performance liquid chromatographic method for the determination of bisoprolol fumarate and hydrochlorothiazide in a tablet dosage form.
Topics: Acetonitriles; Adrenergic beta-Antagonists; Bisoprolol; Buffers; Chlorothiazide; Chromatography, Hig | 2008 |
Liquid chromatographic-tandem mass spectrometric method for the simultaneous quantitation of telmisartan and hydrochlorothiazide in human plasma.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Calibration; Chromatography, Liq | 2008 |
Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis.
Topics: Administration, Oral; Adult; Benzothiadiazines; Biomarkers, Pharmacological; Chlorothiazide; Chromat | 2009 |
RP-HPLC method for simultaneous estimation of bisoprolol fumarate and hydrochlorothiazide in tablet formulation.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Chemistry, Pharmaceutical; Chromatography, High Pressure Li | 2010 |
High performance liquid chromatography/negative ion electrospray tandem mass spectrometry method for the measurement of hydrochlorothiazide in human plasma: application to a comparative bioavailability study.
Topics: Chromatography, High Pressure Liquid; Diuretics; Humans; Hydrochlorothiazide; Plasma; Reference Stan | 2009 |
Stability indicating LC method for simultaneous determination of irbesartan and hydrochlorothiazide in pharmaceutical preparations.
Topics: Biphenyl Compounds; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinatio | 2010 |
Validated chromatographic methods for determination of hydrochlorothiazide and spironolactone in pharmaceutical formulation in presence of impurities and degradants.
Topics: Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Contamination; Drug Stability; Hydrochloroth | 2011 |
[Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography].
Topics: Bumetanide; Chromatography, High Pressure Liquid; Clopamide; Cyclobutanes; Food Contamination; Food, | 2010 |
Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction.
Topics: Animals; Area Under Curve; Chromatography, High Pressure Liquid; Drug Stability; Hydrochlorothiazide | 2011 |
Stability-indicating method for simultaneous estimation of olmesartan medoxomile, amlodipine besylate and hydrochlorothiazide by RP-HPLC in tablet dosage form.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Hyd | 2012 |
Simultaneous acquisition of the dissolution curves of two active ingredients in a binary pharmaceutical association, employing an on-line circulation system and chemometrics-assistance.
Topics: Bisoprolol; Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Fumarates; Hydroch | 2013 |
Concurrent estimation of amlodipine besylate, hydrochlorothiazide and valsartan by RP-HPLC, HPTLC and UV-spectrophotometry.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; | 2014 |
Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma by liquid chromatography.
Topics: Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Diuretics; Humans | 2003 |
Enhancement of radioiodine uptake in hyperthyroidism by administration of hydrochlorothiazide.
Topics: Adult; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Hydrochlorothiazide; Hy | 2003 |
Square wave voltammetric determination of the angiotensin-converting enzyme inhibitors cilazapril, quinapril and ramipril in pharmaceutical formulations.
Topics: Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Drug Combinations; Hydrochlorothiazide; Potent | 2003 |
Introduction to monitoring. What is what you prescribed actually doing?
Topics: Acetaminophen; Aged; Aspirin; Australia; Celecoxib; Drug Interactions; Drug Therapy, Combination; Fa | 2003 |
Development of solid-phase extraction method and its application for determination of hydrochlorothiazide in human plasma using HPLC.
Topics: Chromatography, High Pressure Liquid; Diuretics; Humans; Hydrochlorothiazide; Reference Standards; R | 2004 |
Sensitive and selective liquid chromatography-electrospray ionization tandem mass spectrometry analysis of hydrochlorothiazide in rat plasma.
Topics: Animals; Area Under Curve; Chromatography, Liquid; Diuretics; Hydrochlorothiazide; Rats; Reproducibi | 2004 |
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liqu | 2005 |
Sensitive liquid chromatography-tandem mass spectrometry method for quantification of hydrochlorothiazide in human plasma.
Topics: Antidiuretic Agents; Antihypertensive Agents; Chromatography, High Pressure Liquid; Drug Stability; | 2005 |
Application of first-derivative, ratio derivative spectrophotometry, TLC-densitometry and spectrofluorimetry for the simultaneous determination of telmisartan and hydrochlorothiazide in pharmaceutical dosage forms and plasma.
Topics: Benzimidazoles; Benzoates; Chromatography, Thin Layer; Densitometry; Drug Combinations; Humans; Hydr | 2005 |
A rapid and specific approach for direct measurement of pravastatin concentration in plasma by LC-MS/MS employing solid-phase extraction.
Topics: Administration, Oral; Anticholesteremic Agents; Calibration; Chromatography, Liquid; Humans; Hydroch | 2007 |
Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry.
Topics: Antihypertensive Agents; Chemical Fractionation; Drug Combinations; Drug Monitoring; Humans; Hydroch | 2007 |
A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of valsartan and hydrochlorothiazide in human plasma.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Reference Standards; Reproducibil | 2007 |
Determination of hydrochlorothiazide in human plasma by liquid chromatography/tandem mass spectrometry.
Topics: Administration, Oral; Antihypertensive Agents; Biphenyl Compounds; Chromatography, Liquid; Diuretics | 2007 |
A thiazide test for the diagnosis of renal tubular hypokalemic disorders.
Topics: Adolescent; Adult; Bartter Syndrome; Child; Chronic Disease; Cohort Studies; Diagnosis, Differential | 2007 |
Simple method for determination of hydrochlorothiazide in human urine by high performance liquid chromatography utilizing narrowbore chromatography.
Topics: Black People; Chromatography, High Pressure Liquid; Diuretics; Female; Humans; Hydrochlorothiazide; | 1998 |
Thin-layer chromatography-mass spectrometry using activated carbon, surface-assisted laser desorption/ionization.
Topics: Bradykinin; Carbon; Chromatography, Thin Layer; Diuretics; Glycerol; Hydrochlorothiazide; Lasers; Ma | 1998 |
Simultaneous determination of benazepril hydrochloride and hydrochlorothiazide by micro-bore liquid chromatography.
Topics: Antihypertensive Agents; Benzazepines; Calibration; Chromatography, High Pressure Liquid; Drug Combi | 1999 |
Validation of tablet dissolution method by high-performance liquid chromatography.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chromatography, High Pressure Liq | 2000 |
Simultaneous determination of losartan and hydrochlorothiazide in tablets by high-performance liquid chromatography.
Topics: Antihypertensive Agents; Calibration; Chromatography, High Pressure Liquid; Diuretics; Hydrochloroth | 2000 |
A stability-indicating LC method for the simultaneous determination of ramipril and hydrochlorothiazide in dosage forms.
Topics: Chromatography, High Pressure Liquid; Dosage Forms; Hydrochlorothiazide; Pharmaceutical Preparations | 2001 |
The use of a response surface methodology on HPLC analysis of methyldopa, amiloride and hydrochlorothiazide in tablets.
Topics: Amiloride; Calibration; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Methyldopa; Refer | 2001 |
Analysis of binary mixtures of losartan potassium and hydrochlorothiazide by using high performance liquid chromatography, ratio derivative spectrophotometric and compensation technique.
Topics: Chromatography, High Pressure Liquid; Hydrochlorothiazide; Losartan; Reproducibility of Results; Sen | 2001 |