A protein that is a translation product of the LmjF06.0860 gene in Leishmania major. [PRO:DNx, UniProtKB:P07382]
DHFR-TS
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| doxorubicin hydrochloride | Leishmania major | IC50 | 0.0300 | 1 | 1 |
| trimethoprim | Leishmania major | IC50 | 20.5000 | 1 | 1 |
| trimethoprim | Leishmania major | Ki | 0.1200 | 1 | 1 |
| indole-3-carbaldehyde | Leishmania major | IC50 | 2,000.0000 | 1 | 1 |
| 4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine | Leishmania major | Ki | 12.5892 | 1 | 1 |
| methotrexate | Leishmania major | Ki | 0.0001 | 1 | 1 |
| cb 3717 | Leishmania major | Ki | 0.0940 | 1 | 5 |