Page last updated: 2024-08-07 13:03:25
Substance-K receptor
A substance-K receptor that is encoded in the genome of rat. [OMA:P16610, PRO:DNx]
Synonyms
SKR;
NK-2 receptor;
NK-2R;
Neurokinin A receptor;
Tachykinin receptor 2
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (10)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| pyrimethamine | Rattus norvegicus (Norway rat) | Ki | 0.0717 | 1 | 1 |
| substance p | Rattus norvegicus (Norway rat) | IC50 | 0.2000 | 1 | 1 |
| 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan | Rattus norvegicus (Norway rat) | IC50 | 0.3981 | 1 | 1 |
| 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan | Rattus norvegicus (Norway rat) | Ki | 0.1340 | 1 | 1 |
| sr 142806 | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| thiram | Rattus norvegicus (Norway rat) | EC50 | 0.4000 | 1 | 0 |
| helenalin | Rattus norvegicus (Norway rat) | EC50 | 0.1800 | 1 | 0 |
| substance p | Rattus norvegicus (Norway rat) | EC50 | 0.1670 | 1 | 1 |
| senktide | Rattus norvegicus (Norway rat) | EC50 | 200.0000 | 1 | 2 |
| N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester | Rattus norvegicus (Norway rat) | EC50 | 3.1300 | 1 | 0 |
| neurokinin a | Rattus norvegicus (Norway rat) | EC50 | 0.0223 | 3 | 3 |
| neurokinin b | Rattus norvegicus (Norway rat) | EC50 | 0.0270 | 1 | 1 |