Proteins > Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Page last updated: 2024-08-07 14:53:08
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of mouse. [OMA:P97287, PRO:DNx]
Synonyms
Bcl-2-related protein EAT/mcl1
Research
Bioassay Publications (4)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
marinopyrrole a | Mus musculus (house mouse) | IC50 | 10.1000 | 3 | 3 |
Drugs with Activation Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
abt-737 | Mus musculus (house mouse) | Kd | 1.0000 | 1 | 1 |
Structure-Based Optimization of 3-Phenyl-Journal of medicinal chemistry, , 07-22, Volume: 64, Issue:14, 2021
Small-molecule Mcl-1 inhibitors: Emerging anti-tumor agents.European journal of medicinal chemistry, , Feb-25, Volume: 146, 2018
Expanding the Cancer Arsenal with Targeted Therapies: Disarmament of the Antiapoptotic Bcl-2 Proteins by Small Molecules.Journal of medicinal chemistry, , 02-09, Volume: 60, Issue:3, 2017