Proteins > Cruzipain
Page last updated: 2024-08-07 16:17:57

Cruzipain

[no definition available]

Synonyms

EC 3.4.22.51;
Cruzaine;
Major cysteine proteinase

Research

Bioassay Publications (18)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's12 (66.67)24.3611
2020's2 (11.11)2.80

Compounds (54)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
aurintricarboxylic acidTrypanosoma cruziIC5040.500022
candesartan cilexetilTrypanosoma cruziIC50105.000022
celecoxibTrypanosoma cruziIC50263.000022
clofazimineTrypanosoma cruziIC5023.000044
fenofibrateTrypanosoma cruziIC50280.500022
itraconazoleTrypanosoma cruziIC50101.500022
manidipineTrypanosoma cruziIC5053.000022
ono 1078Trypanosoma cruziIC5037.500022
raloxifeneTrypanosoma cruziIC5073.666733
imatinibTrypanosoma cruziIC50252.000022
methylene blueTrypanosoma cruziIC5070.000022
chlorpromazine hydrochlorideTrypanosoma cruziIC50236.500022
5-bromoisatinTrypanosoma cruziIC5010.000011
isatinTrypanosoma cruziIC5010.000022
5-methylisatinTrypanosoma cruziIC5010.000011
n-methylisatinTrypanosoma cruziIC5010.000011
tocopheryl nicotinateTrypanosoma cruziIC50249.000022
triclabendazoleTrypanosoma cruziIC50107.500022
nelfinavirTrypanosoma cruziIC50222.000022
5-Chloro-1H-indole-2,3-dioneTrypanosoma cruziIC5010.000011
5-iodoisatinTrypanosoma cruziIC5010.000011
meclizine hydrochlorideTrypanosoma cruziIC50189.500022
plavixTrypanosoma cruziIC50211.500022
gefitinibTrypanosoma cruziIC50118.000022
e 64Trypanosoma cruziIC500.210022
etravirineTrypanosoma cruziIC50102.000022
5-FluoroisatinTrypanosoma cruziIC5010.000011
nsc-260594Trypanosoma cruziIC5063.000011
amiodarone hydrochlorideTrypanosoma cruziIC50105.000022
delavirdine mesylateTrypanosoma cruziIC50161.000022
N-[2-[5-[(2,4-dichlorophenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamic acid tert-butyl esterTrypanosoma cruziIC50282.500022
isatin beta-thiosemicarbazoneTrypanosoma cruziIC505.750022
N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamideTrypanosoma cruziIC500.800011
N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamideTrypanosoma cruziKi2.000011
cinnarizineTrypanosoma cruziIC50212.000022
d 609Trypanosoma cruziIC50307.500022
5-NitroisatinTrypanosoma cruziIC5010.000022
7-chloro-N-(phenylmethyl)-4-quinolinamineTrypanosoma cruziIC5044.000011
luteolinTrypanosoma cruziIC5091.500022
genisteinTrypanosoma cruziIC50241.350022
fisetinTrypanosoma cruziIC5045.000022
ellagic acidTrypanosoma cruziIC50142.000022
menatetrenoneTrypanosoma cruziIC50109.000022
2-acetylpyridine thiosemicarbazoneTrypanosoma cruziIC5020.000011
am 404Trypanosoma cruziIC5045.000022
3-hydroxy-4-methoxybenzaldehyde thiosemicarbazoneTrypanosoma cruziIC5010.000011
l 755507Trypanosoma cruziIC5036.000022
odanacatibTrypanosoma cruziKi0.125911
gallinamide aTrypanosoma cruziIC500.000822
4-(3,5-difluoroanilino)-6-(2,2-difluoroethylamino)-1,3,5-triazine-2-carbonitrileTrypanosoma cruziIC500.013022
6-(3-chloroanilino)-9-cyclopentyl-2-purinecarbonitrileTrypanosoma cruziIC500.020222
6-(3,5-difluoroanilino)-9-ethyl-2-purinecarbonitrileTrypanosoma cruziIC500.005122
6-(3,5-difluoroanilino)-9-(2,2-difluoroethyl)-2-purinecarbonitrileTrypanosoma cruziIC500.013011
6-(3-chloroanilino)-9-ethyl-2-purinecarbonitrileTrypanosoma cruziIC500.009222
9-(3,5-difluorophenyl)-6-(ethylamino)-2-purinecarbonitrileTrypanosoma cruziIC500.251011