Proteins > Voltage-dependent calcium channel gamma-6 subunit
Page last updated: 2024-08-07 19:51:35

Voltage-dependent calcium channel gamma-6 subunit

A voltage-dependent calcium channel gamma-6 subunit that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BXT2]

Synonyms

Neuronal voltage-gated calcium channel gamma-6 subunit

Research

Bioassay Publications (2)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (3)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
tacrineHomo sapiens (human)IC5017.000011
nimodipineHomo sapiens (human)IC5014.000011
ith 4012Homo sapiens (human)IC5020.000011

Enables

This protein enables 2 target(s):

TargetCategoryDefinition
voltage-gated calcium channel activitymolecular functionEnables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. [GOC:mtg_transport, GOC:tb, ISBN:0815340729]
calcium channel regulator activitymolecular functionModulates the activity of a calcium channel. [GOC:mah]

Located In

This protein is located in 1 target(s):

TargetCategoryDefinition
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

Part Of

This protein is part of 2 target(s):

TargetCategoryDefinition
voltage-gated calcium channel complexcellular componentA protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. [GOC:mah]
L-type voltage-gated calcium channel complexcellular componentA type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation. [GOC:ame, PMID:12946355]

Involved In

This protein is involved in 3 target(s):

TargetCategoryDefinition
calcium ion transportbiological processThe directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]
calcium ion transmembrane transportbiological processA process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]
regulation of calcium ion transmembrane transport via high voltage-gated calcium channelbiological processAny process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel. [GOC:dph, GOC:pg, GOC:TermGenie, PMID:1611048]