1-methoxy-5-methylphenazinium methyl sulfate profile

1-methoxy-5-methylphenazinium methyl sulfate, also known as **methyl viologen**, is a heterocyclic organic compound with the chemical formula C₁₄H₁₆N₂O₄S. It is important for research for several reasons:

**1. Redox Properties:**

* **Electron acceptor:** Methyl viologen readily accepts electrons, making it a powerful electron acceptor. It is easily reduced to a blue radical cation, which can then be further reduced to a colorless neutral species. This property makes it useful for various research applications like:
* **Redox chemistry and electrochemistry:** Studying electron transfer reactions and mechanisms.
* **Photochemistry:** Acting as a mediator in photocatalytic reactions.
* **Biochemistry:** Studying electron transfer processes in biological systems.

**2. Photochemical Properties:**

* **Photosensitizer:** When irradiated with UV light, methyl viologen can undergo photochemical reactions. This property makes it useful for:
* **Photocatalysis:** Generating reactive oxygen species (ROS) for various applications like environmental remediation and organic synthesis.
* **Photodynamic therapy:** Killing cancer cells using light-activated processes.

**3. Agricultural Applications:**

* **Herbicide:** Methyl viologen, also known as **paraquat**, is a widely used herbicide. It disrupts the electron transport chain in plants, leading to oxidative stress and cell death. However, due to its toxicity and environmental concerns, its use is being phased out in many countries.

**4. Other Research Applications:**

* **Analytical Chemistry:** Methyl viologen can be used as a reagent for various analytical techniques like spectrophotometry and electrochemistry.
* **Material Science:** It can be incorporated into functional materials like polymers and nanoparticles for applications in sensing, energy storage, and electronics.

**Overall, methyl viologen is a versatile compound with a wide range of applications in various research fields. Its redox and photochemical properties, coupled with its relatively low cost and ease of synthesis, make it a valuable tool for scientists.**

It is important to note that while methyl viologen is a valuable research tool, it is also a highly toxic substance. Proper handling and safety precautions are crucial when working with this compound.

ID Source	ID
PubMed CID	127832
SCHEMBL ID	483707
MeSH ID	M0080888

Synonym
1-methoxy-5-methylphenazinium methyl sulfate
65162-13-2
M1442
1-methoxy-5-methylphenazinium methyl sulphate
1-methoxy-5-methylphenazin-5-ium methyl sulfate
1-methoxy-5-methylphenazonium methosulfate
x2or19pg1u ,
einecs 265-579-6
unii-x2or19pg1u
phenazinium, 1-methoxy-5-methyl-, methyl sulfate
FT-0608009
CS-5925
methoxy-pms
HY-D0937
SCHEMBL483707
indole-2,5-dicarboxylicacid2-ethylester5-methylester
AC-35238
AKOS024465055
1-methoxy-5-methylphenazinium methylsulfate
mfcd00040648
DTXSID40215474
1-methoxy-5-methyl-1,5-dihydrophenazin-1-ylium methyl sulfate
AS-66132
1-methoxy pms
methoxyphenazine-methosulfate
BCP04440
1-methoxy pms;1-methoxyphenazine methosulfate
A867733
1-methoxy-5-methylphenazin-5-ium;methyl sulfate
F11462
AB91869
1-methoxy-5-methylphenazinium (methyl sulfate)
1-methoxy-5-methyl-phenazin-5-ium;methyl sulfate
EX-A8006D

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	2 (18.18)	18.7374
1990's	1 (9.09)	18.2507
2000's	5 (45.45)	29.6817
2010's	3 (27.27)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
acetic acid Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.	2.06	1	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent
aminooxyacetic acid Aminooxyacetic Acid: A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.. (aminooxy)acetic acid : A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.	2.02	1	amino acid; hydroxylamines; monocarboxylic acid	anticonvulsant; EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor; EC 4.2.1.22 (cystathionine beta-synthase) inhibitor; nootropic agent
methane Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed). methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).	2.07	1	alkane; gas molecular entity; mononuclear parent hydride; one-carbon compound	bacterial metabolite; fossil fuel; greenhouse gas
1-octanol 1-Octanol: A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticizers. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed). octan-1-ol : An octanol carrying the hydroxy group at position 1.	2.02	1	octanol; primary alcohol	antifungal agent; bacterial metabolite; fuel additive; kairomone; plant metabolite
sulfuric acid sulfuric acid : A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.	2.01	1	sulfur oxoacid	catalyst
uric acid Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.. uric acid : An oxopurine that is the final oxidation product of purine metabolism.. 6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.. 7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.	2	1	uric acid	Escherichia coli metabolite; human metabolite; mouse metabolite
carbonyl cyanide p-trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone: A proton ionophore that is commonly used as an uncoupling agent in biochemical studies.. carbonyl cyanide p-trifluoromethoxyphenylhydrazone : A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.	2.03	1	aromatic ether; hydrazone; nitrile; organofluorine compound	ATP synthase inhibitor; geroprotector; ionophore
vitamin k 3 Vitamin K 3: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.	2.15	1	1,4-naphthoquinones; vitamin K	angiogenesis inhibitor; antineoplastic agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; human urinary metabolite; nutraceutical
aspartic acid Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.	2.06	1	aspartate family amino acid; aspartic acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; mouse metabolite; neurotransmitter
n-octanethiol octane-1-thiol : An alkanethiol that is octane substituted by a thiol group at position 1.	2	1	alkanethiol
thiazoles [no description available]	2.03	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
methylphenazonium methosulfate Methylphenazonium Methosulfate: Used as an electron carrier in place of the flavine enzyme of Warburg in the hexosemonophosphate system and also in the preparation of SUCCINIC DEHYDROGENASE.	3.8	11	azaheterocycle sulfate salt; phenazines
2,6-dichloroindophenol 2,6-Dichloroindophenol: A dye used as a reagent in the determination of vitamin C.. 2,6-dichloroindophenol : A quinone imine that is indophenol substituted by chloro groups at positions 2 and 6.. N-3,5-dichloro-4-hydroxyphenyl-1,4-benzoquinone imine : 1,4-benzoquinone imine having a 3,5-dichloro-4-hydroxyphenyl substituent attached to the nitrogen atom.	2.02	1	dichlorobenzene; quinone imine
gold Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.	2	1	copper group element atom; elemental gold
d-aspartic acid [no description available]	2.06	1	aspartic acid; D-alpha-amino acid	mouse metabolite
nadp [no description available]	2.01	1
silicon Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].	2.07	1	carbon group element atom; metalloid atom; nonmetal atom
monorden monorden: inhibits HSP90 Heat-Shock Proteins, DNA topoisomerase VI and human Topoisomerase II	2.02	1	cyclic ketone; enone; epoxide; macrolide antibiotic; monochlorobenzenes; phenols	antifungal agent; metabolite; tyrosine kinase inhibitor
1-palmitoyl-2-oleoylphosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine: RN given refers to (Z)-isomer	2	1
myxothiazol myxothiazol: strobilurin analogue; methoxyacrylamide derivative; antifungal antibiotic from Myxococcus fulvus; structure given in first source. myxothiazol : A 2,4'-bi-1,3-thiazole substituted at the 4-position with a (1E,3S,4R,5E)-7-amino-3,5-dimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl] group and at the 2'-position with a (2S,3E,5E)-7-methylocta-3,5-dien-2-yl group. It is an inhibitor of coenzyme Q - cytochrome c reductase.	2.03	1
bromopyruvate [no description available]	2.15	1	2-oxo monocarboxylic acid anion
formazans Formazans: Colored azo compounds formed by the reduction of tetrazolium salts. Employing this reaction, oxidoreductase activity can be determined quantitatively in tissue sections by allowing the enzymes to act on their specific substrates in the presence of tetrazolium salts.	2.46	2
nad NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.	2.96	4	organophosphate oxoanion	cofactor; human metabolite; hydrogen acceptor; Saccharomyces cerevisiae metabolite
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	2	1	1,2-diacyl-sn-glycero-3-phosphocholine
ubiquinone Ubiquinone: A lipid-soluble benzoquinone which is involved in ELECTRON TRANSPORT in mitochondrial preparations. The compound occurs in the majority of aerobic organisms, from bacteria to higher plants and animals.	2.02	1

Condition	Relationship Strength	Studies
Glial Cell Tumors [description not available]	2.15	1
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)	2.15	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.7	3
Osteogenic Sarcoma [description not available]	2.02	1
Osteosarcoma A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)	2.02	1

1-methoxy-5-methylphenazinium methyl sulfate

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