Page last updated: 2024-10-15
8,5'-cyclo-2'-deoxyguanosine
Description
8,5'-cyclo-2'-deoxyguanosine: RN given refers to (5'R)-isomer in Toxline; RN not in Chemline 1/87 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
8,5'-cyclo-2'-deoxyguanosine : An organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of 2'-deoxyguanosine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
Synonyms (14)
| Synonym |
|---|
| 8,5'-cyclo-2'-deoxyguanosine |
| cyclo-dg |
| cyclodg |
| 104504-22-5 |
| CHEBI:131828 |
| 2'-deoxy-8,5'-cycloguanosine |
| 8,5'-cyclo-dg |
| (6r,7s,8s,10r)-2-amino-6,8-dihydroxy-1,6,7,8,9,10-hexahydro-4h-7,10-epoxyazepino[1,2-e]purin-4-one |
| Q27225268 |
| (1r,11r,12s,13s)-5-amino-11,13-dihydroxy-15-oxa-2,4,6,9-tetrazatetracyclo[10.2.1.02,10.03,8]pentadeca-3(8),4,9-trien-7-one |
| DTXSID60909020 |
| 2-imino-1,6,7,8,9,10-hexahydro-2h-7,10-epoxyazepino[1,2-e]purine-4,6,8-triol |
| (1r,11r,12s,13s)-5-amino-11,13-dihydroxy-15-oxa-2,4,6,9-tetrazatetracyclo[10.2.1.02,10.03,8]pentadeca-3(8),5,9-trien-7-one |
| 8,5/'-cyclo-2/'-deoxyguanosine |
Roles (1)
| Role | Description |
|---|
| Mycoplasma genitalium metabolite | Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (5)
| Class | Description |
|---|
| N-glycosyl compound | A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. |
| aromatic amine | An amino compound in which the amino group is linked directly to an aromatic system. |
| bridged compound | A polycyclic compound in which two rings have two or more atoms in common. |
| diol | A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. |
| organic heterotetracyclic compound | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (26)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 18 (69.23) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (11.54%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 23 (88.46%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |