Page last updated: 2024-08-07 14:46:35
DNA gyrase subunit B
[no definition available]
Synonyms
EC 5.6.2.2
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| moxifloxacin | Mycolicibacterium smegmatis | IC50 | 50.0000 | 3 | 3 |
| novobiocin | Mycolicibacterium smegmatis | IC50 | 25.8523 | 7 | 7 |
Design and synthesis of novel quinoline-aminopiperidine hybrid analogues as Mycobacterium tuberculosis DNA gyraseB inhibitors.Bioorganic & medicinal chemistry, , May-01, Volume: 23, Issue:9, 2015
4-Aminoquinoline derivatives as novel Mycobacterium tuberculosis GyrB inhibitors: Structural optimization, synthesis and biological evaluation.European journal of medicinal chemistry, , Oct-20, Volume: 103, 2015
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.Bioorganic & medicinal chemistry, , Sep-01, Volume: 22, Issue:17, 2014
Mycobacterium Tuberculosis (MTB) GyrB inhibitors: An attractive approach for developing novel drugs against TB.European journal of medicinal chemistry, , Nov-29, Volume: 124, 2016
Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.Bioorganic & medicinal chemistry, , Apr-01, Volume: 23, Issue:7, 2015
Design and synthesis of novel quinoline-aminopiperidine hybrid analogues as Mycobacterium tuberculosis DNA gyraseB inhibitors.Bioorganic & medicinal chemistry, , May-01, Volume: 23, Issue:9, 2015
4-Aminoquinoline derivatives as novel Mycobacterium tuberculosis GyrB inhibitors: Structural optimization, synthesis and biological evaluation.European journal of medicinal chemistry, , Oct-20, Volume: 103, 2015
An efficient synthesis and biological screening of benzofuran and benzo[d]isothiazole derivatives for Mycobacterium tuberculosis DNA GyrB inhibition.Bioorganic & medicinal chemistry, , Dec-01, Volume: 22, Issue:23, 2014
Design, synthesis, biological evaluation of substituted benzofurans as DNA gyraseB inhibitors of Mycobacterium tuberculosis.Bioorganic & medicinal chemistry, , Sep-01, Volume: 22, Issue:17, 2014
Thiazole-aminopiperidine hybrid analogues: design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors.European journal of medicinal chemistry, , Volume: 70, 2013