Page last updated: 2024-12-06

trimethylarsine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

trimethylarsine : An arsine that is arsane in which each of the hydrogens is substituted by a methyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID68978
CHEBI ID27130
MeSH IDM0054399

Synonyms (18)

Synonym
593-88-4
CHEBI:27130
(ch3)3as
trimethylarsane
asme3
einecs 209-815-8
brn 1730780
arsine, trimethyl-
trimethylarsenic
trimethylarsine
mq83uq8a1q ,
unii-mq83uq8a1q
4-04-00-03665 (beilstein handbook reference)
DTXSID4073203
mfcd00014838
trimethylarsine, elec. gr.
FT-0767762
Q421500

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"Trimethylarsine (TM-As) proved to be an arsenic compound of low toxicity, with a po LD50 of 7870 mg/kg in mice."( Toxicity and metabolism of trimethylarsine in mice and hamsters.
Kaise, T; Takahashi, K; Yamamura, Y; Yamauchi, H, 1990
)
2.02

Compound-Compound Interactions

ExcerptReferenceRelevance
"The simultaneous detection of arsenic and sulfur in thioarsenicals was achieved using xenon-based collision-cell inductively coupled plasma (ICP) mass spectrometry (MS) in combination with high-performance liquid chromatography."( Complementary molecular and elemental detection of speciated thioarsenicals using ESI-MS in combination with a xenon-based collision-cell ICP-MS with application to fortified NIST freeze-dried urine.
Caruso, JA; Conklin, SD; Creed, JT; Creed, PA; Ellis, JL; Gallawa, CM; Kubachka, KM; Young, AR, 2008
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
arsineArsane (AsH3) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RAsH2, R2AsH, R3As (R =/= H) are called primary, secondary and tertiary arsines, respectively. A specific arsine is preferably named as a substituted arsane.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (31.82)18.7374
1990's2 (9.09)18.2507
2000's11 (50.00)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.89

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.89 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.87 (4.65)
Search Engine Demand Index33.89 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.89)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.55%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (95.45%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]