4-nitrophenylacetic acid profile

4-Nitrophenylacetic acid (4-NPA) is a synthetic organic compound used in various research and industrial applications. Its synthesis often involves the nitration of phenylacetic acid with a mixture of nitric acid and sulfuric acid. 4-NPA is known to exhibit biological activity, particularly as a substrate for the enzyme peroxidase, and is often used in studies of enzyme kinetics and mechanisms. The compound's potential for inhibiting the growth of certain bacteria and fungi makes it relevant for research on antimicrobial agents. 4-NPA has also been explored as a starting material in the synthesis of other organic compounds, including pharmaceuticals. Its unique structure and properties make it a subject of ongoing research in fields such as biochemistry, medicinal chemistry, and materials science.'

4-nitrophenylacetic acid: don't confuse with 4-Nitrophenyl acetate, which is the ester of phenol and acetic acid [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

(4-nitrophenyl)acetic acid : A member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the para- position by a nitro group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	4661
CHEBI ID	40443
SCHEMBL ID	76204
SCHEMBL ID	13941612
MeSH ID	M0302637

Synonym
4-nitrophenylaceticacid
ai3-15093
ccris 2338
einecs 203-168-5
4-nitrophenylacetic acid
nsc 5398
2-(p-nitrophenyl)acetic acid
(p-nitrophenyl)acetic acid
BB 0244245
nsc-5398
p-nitrophenylacetic acid
nsc5398
4-nitrobenzeneacetic acid
104-03-0
benzeneacetic acid, 4-nitro-
(4-nitrophenyl)acetic acid
acetic acid, (p-nitrophenyl)-
OPREA1_127303
inchi=1/c8h7no4/c10-8(11)5-6-1-3-7(4-2-6)9(12)13/h1-4h,5h2,(h,10,11
SR-01000631614-1
4-nitrophenylacetic acid, reagentplus(r), 99%
1AJN ,
2-(4-nitrophenyl)acetic acid
STK054869
AC-2513
AKOS000104752
DB07331
N0227
AE-641/02392058
unii-klb4p626re
klb4p626re ,
BBL012452
CCG-41548
FT-0619270
AM20060474
S12333
p-nitro-.alpha.-toluic acid
4-nitrophenylacetic acid [mi]
SCHEMBL76204
SCHEMBL13941612
DTXSID6059289
CHEBI:40443
4-nitrophenyl acetic acid
(p-nitrophenyl) acetic acid
(4-nitro-phenyl)-acetic acid
(4-nitrophenyl)-acetic acid
STR00634
4-nitrobenzencacetic acid
W-108829
4-nitrophenylacetate acid
HMS3604G17
F2191-0048
mfcd00007383
4-nitrophenylacetic acid, vetec(tm) reagent grade, 98%
CS-D1370
bdbm237235
SY001731
4-nitro-benzeneacetic acid,
Q27096559
p-nitrophenyl acetic acid
4-nitrophenylaetic acid
EN300-20166
Z104477118
AKOS040744590

Excerpt	Relevance	Reference
" The overall hydrolytic activity in the liver microsomes toward both 1-naphthyl- and para-nitrophenylacetate was markedly increased in the nonlethal dosage groups, but markedly decreased in the lethal dosage group."	( Regulation of rat carboxylesterase expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): a dose-dependent decrease in mRNA levels but a biphasic change in protein levels and activity. Li, Y; Matoney, L; Yan, B; Yang, D; Yuan, X, 2001)	0.31

Class	Description
C-nitro compound	A nitro compound having the nitro group (-NO2) attached to a carbon atom.
phenylacetic acids	Any monocarboxylic acid that is phenylacetic acid or its substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain A, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
Chain B, Penicillin Amidohydrolase	Escherichia coli	Ki	2,320.0000	82.0000	2,297.8000	5,850.0000	AID977610
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Assay ID	Title	Year	Journal	Article
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).	2014	Journal of biomolecular screening, Jul, Volume: 19, Issue:6	A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
AID977610	Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB	1998	Journal of molecular biology, Nov-27, Volume: 284, Issue:2	Ligand-induced conformational change in penicillin acylase.
AID1159607	Screen for inhibitors of RMI FANCM (MM2) intereaction	2016	Journal of biomolecular screening, Jul, Volume: 21, Issue:6	A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	4 (14.29)	18.2507
2000's	15 (53.57)	29.6817
2010's	8 (28.57)	24.3611
2020's	1 (3.57)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	28 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
4-hydroxyphenylacetic acid 4-hydroxyphenylacetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group.	1.99	1	monocarboxylic acid; phenols	fungal metabolite; human metabolite; mouse metabolite; plant metabolite
carbamates [no description available]	2.04	1	amino-acid anion
octane Octanes: Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. octane : A straight chain alkane composed of 8 carbon atoms.	2.01	1	alkane	xenobiotic
phloroglucinol Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.. phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.	2.07	1	benzenetriol; phenolic donor	algal metabolite
3,4-dihydroxyphenylacetic acid 3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.. (3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.. dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.	1.99	1	catechols; dihydroxyphenylacetic acid	human metabolite
glycine [no description available]	2.11	1	alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid	EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical
homogentisic acid Homogentisic Acid: Dihydroxyphenylacetic acid with hydroxyls at the 2 and 5 positions of the phenyl ring.. homogentisic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents at the 2- and 5-positions.	1.99	1	dihydroxyphenylacetic acid; hydroquinones	human metabolite; plant metabolite
phenol [no description available]	1.99	1	phenols	antiseptic drug; disinfectant; human xenobiotic metabolite; mouse metabolite
phenylacetic acid phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.	2.71	3	benzenes; monocarboxylic acid; phenylacetic acids	allergen; Aspergillus metabolite; auxin; EC 6.4.1.1 (pyruvate carboxylase) inhibitor; Escherichia coli metabolite; human metabolite; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite; toxin
1,10-phenanthroline 1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases	2	1	phenanthroline	EC 2.7.1.1 (hexokinase) inhibitor; EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
acetazolamide Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)	2.08	1	monocarboxylic acid amide; sulfonamide; thiadiazoles	anticonvulsant; diuretic; EC 4.2.1.1 (carbonic anhydrase) inhibitor
ethacrynic acid Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.. etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.	2.92	1	aromatic ether; aromatic ketone; dichlorobenzene; monocarboxylic acid	EC 2.5.1.18 (glutathione transferase) inhibitor; ion transport inhibitor; loop diuretic
isocarboxazid Isocarboxazid: An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)	2	1	benzenes
phenylmethylsulfonyl fluoride Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.. phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.	2.01	1	acyl fluoride	serine proteinase inhibitor
fluoroacetic acid fluoroacetic acid: N1 same as NM; RN given refers to parent cpd. fluoroacetic acid : A haloacetic acid that is acetic acid in which one of the methyl hydrogens is substituted by fluorine.	2.92	1	haloacetic acid; organofluorine compound	EC 4.2.1.3 (aconitate hydratase) inhibitor
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	2.01	1	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
lysine Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.	2	1	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
phenylalanine Phenylalanine: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.. L-phenylalanine : The L-enantiomer of phenylalanine.. phenylalanine : An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.	2.11	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
histidine Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.	2	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
arginine Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.	2	1	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical
dichloroacetic acid [no description available]	2.92	1	monocarboxylic acid; organochlorine compound	astringent; marine metabolite
1-naphthaleneacetic acid 1-naphthaleneacetic acid: a plant growth regulator; RN given refers to parent cpd. naphthylacetic acid : A monocarboxylic acid that is naphthalene substituted by a carboxymethyl group at any position.. 1-naphthaleneacetic acid : A naphthylacetic acid substituted by a carboxymethyl group at position 1.	2.41	2	naphthylacetic acid	synthetic auxin
nitrobenzene nitrobenzene : A nitroarene consisting of benzene carrying a single nitro substituent. An industrial chemical used widely in the production of aniline.	2.06	1	nitroarene; nitrobenzenes
2,6-diaminopyridine 2,6-diaminopyridine: structure in first source	7.11	1
paraoxon [no description available]	2.42	2	aryl dialkyl phosphate; organophosphate insecticide	EC 3.1.1.7 (acetylcholinesterase) inhibitor; mouse metabolite
2,2,4-trimethylpentane 2,2,4-trimethylpentane: nephrotoxic. isooctane : An alkane that consists of pentane bearing two methyl substituents at position 2 and a single methyl substituent at position 4.	2.01	1	alkane; volatile organic compound	fuel additive; nephrotoxin; non-polar solvent
docusate Dioctyl Sulfosuccinic Acid: All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.	2.01	1	diester; organosulfonic acid
2-chloropropionic acid 2-chloropropionic acid: RN given refers to parent cpd with specified chlorine locant; structure	2.92	1
acetylcysteine N-acetyl-L-cysteine : An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.	2	1	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
samarium Samarium: An element of the rare earth family of metals. It has the atomic symbol Sm, atomic number 62, and atomic weight 150.36. The oxide is used in the control rods of some nuclear reactors.	2.01	1	f-block element atom; lanthanoid atom
terbium Terbium: An element of the rare earth family of metals. It has the atomic symbol Tb, atomic number 65, and atomic weight 158.92.	2.01	1	f-block element atom; lanthanoid atom
europium Europium: An element of the rare earth family of metals. It has the atomic symbol Eu, atomic number 63, and atomic weight 152. Europium is used in the form of its salts as coatings for cathode ray tubes and in the form of its organic derivatives as shift reagents in NMR spectroscopy.	2.41	2	f-block element atom; lanthanoid atom
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	2.92	1	benzenes; phenyl acetates
1,7-phenanthroline [no description available]	2	1	phenanthroline
4-nitrophenyl butyrate p-nitrophenyl butyrate : A butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid.	2.01	1	butyrate ester; C-nitro compound
2-nitrophenylacetic acid (2-nitrophenyl)acetic acid : A member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the ortho- position by a nitro group.	2.44	2	C-nitro compound; phenylacetic acids
chlorofluoroacetic acid chlorofluoroacetic acid: structure in first source	2.92	1
temocapril hydrochloride temocapril hydrochloride: structure given in first source	2.02	1	dipeptide
nadp [no description available]	2	1
bilirubin [no description available]	2	1	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite
fumarates Fumarates: Compounds based on fumaric acid.. fumarate(2-) : A C4-dicarboxylate that is the E-isomer of but-2-enedioate(2-)	2	1	butenedioate; C4-dicarboxylate	human metabolite; metabolite; Saccharomyces cerevisiae metabolite
oxadiazoles Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.	2.04	1
dextrothyroxine [no description available]	2	1
c-peptide C-Peptide: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.	2.01	1

Condition	Relationship Strength	Studies
Plasmodium falciparum Malaria [description not available]	2.1	1
Malaria, Falciparum Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.	2.1	1
Anemia, Fanconi [description not available]	2.13	1
Fanconi Anemia Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)	2.13	1
Bacterial Disease [description not available]	2.11	1
Fungal Diseases [description not available]	2.11	1
Bacterial Infections Infections by bacteria, general or unspecified.	2.11	1
Mycoses Diseases caused by FUNGI.	2.11	1
Chronic Kidney Failure [description not available]	2.05	1
Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.	2.05	1
Impaired Glucose Tolerance [description not available]	2.01	1
Diabetes Mellitus, Adult-Onset [description not available]	2.01	1
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.	2.01	1
Glucose Intolerance A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.	2.01	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	2	1
Adenocarcinoma, Basal Cell [description not available]	2.01	1
Cancer of Colon [description not available]	2.01	1
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	2.01	1
Colonic Neoplasms Tumors or cancer of the COLON.	2.01	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.01	1

4-nitrophenylacetic acid

Description

Cross-References

Synonyms (64)

Research Excerpts

Dosage Studied

Drug Classes (2)

Protein Targets (14)

Inhibition Measurements

Bioassays (4)

Research

Studies (28)

Market Indicators

Research Demand Index: 32.70

Study Types