Proteins > Vesicular acetylcholine transporter
Page last updated: 2024-08-07 18:06:43
Vesicular acetylcholine transporter
[no definition available]
Synonyms
VAChT;
TorVAChT
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| vesamicol | Tetronarce californica (Pacific electric ray) | IC50 | 0.0340 | 1 | 1 |
| colchicine | Tetronarce californica (Pacific electric ray) | IC50 | 2.6200 | 1 | 1 |
| vesamicol | Tetronarce californica (Pacific electric ray) | IC50 | 0.0340 | 1 | 1 |
| vesamicol | Tetronarce californica (Pacific electric ray) | Ki | 0.0015 | 2 | 2 |
| fosbretabulin | Tetronarce californica (Pacific electric ray) | IC50 | 1.8000 | 1 | 1 |
| benzovesamicol | Tetronarce californica (Pacific electric ray) | Ki | 0.0001 | 3 | 3 |
Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.Journal of medicinal chemistry, , Apr-08, Volume: 53, Issue:7, 2010
Spirovesamicols: conformationally restricted analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol, AH5183) as potential modulators of presynaptic cholinergic function.Journal of medicinal chemistry, , Aug-05, Volume: 37, Issue:16, 1994
Nonsymmetrical bipiperidyls as inhibitors of vesicular acetylcholine storage.Journal of medicinal chemistry, , Apr-16, Volume: 36, Issue:8, 1993
New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure.European journal of medicinal chemistry, , Jul-15, Volume: 100, 2015
Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.Journal of medicinal chemistry, , Apr-08, Volume: 53, Issue:7, 2010
Spirovesamicols: conformationally restricted analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol, AH5183) as potential modulators of presynaptic cholinergic function.Journal of medicinal chemistry, , Aug-05, Volume: 37, Issue:16, 1994