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oxalic acid and Sensitivity and Specificity

oxalic acid has been researched along with Sensitivity and Specificity in 31 studies

Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Oxalic acid was found to be the most appropriate acid among all the acids used for detection in this study."1.34A rapid field detection method for arsenic in drinking water. ( Baghel, A; Pandey, P; Sekhar, K; Singh, B, 2007)
"Oxalic acid was determined in wastewater and in spinach by the proposed method with satisfactory results."1.31Flow injection spectrophotometric determination of ultra trace amounts of oxalic acid. ( Ensafi, AA; Kazemzadeh, A, 2000)
"Patients with primary hyperoxaluria and chronic renal failure exhibited markedly greater plasma concentrations of oxalate."1.29Assay of plasma oxalate with soluble oxalate oxidase. ( Cerelli, E; Cosseddu, D; Linari, F; Marangella, M; Petrarulo, M; Vitale, C, 1994)
"Oxolinic acid was extracted with a mixture of McIlvaine buffer (pH 3."1.29High-performance liquid chromatographic determination of oxolinic acid residues in fish silage. ( Samuelsen, OB, 1994)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's8 (25.81)18.2507
2000's18 (58.06)29.6817
2010's4 (12.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Husáková, L1
Urbanová, I1
Šrámková, J1
Konečná, M1
Bohuslavová, J1
Arrabal-Polo, MA1
Cano-García, MC1
Hidalgo-Agullo, G1
Roletto-Salmo, L1
Jones, P1
Nesterenko, PN1
Hong, YH1
Dublin, N1
Razack, AH1
Mohd, MA1
Husain, R1
Uchihara, T1
Nakamura, A1
Shibuya, K1
Yagishita, S1
Ohta, K1
Kusumoto, K1
Takao, Y1
Towata, A1
Morikawa, H1
Ohashi, M1
Kalapathy, U1
Proctor, A1
Shultz, J1
Hong, F1
Nilvebrant, NO1
Jönsson, LJ1
Bruzzoniti, MC1
Cavalli, S1
Mangia, A1
Mucchino, C1
Sarzanini, C1
Tarasco, E1
Pérez-Ruiz, T1
Martínez-Lozano, C1
Tomás, V1
Martín, J1
Recht, PA1
Tepedino, GJ1
Siecke, NW1
Buckley, MT1
Mandeville, JT1
Maxfield, FR1
Levin, RI1
Hossain, RZ1
Ogawa, Y1
Morozumi, M1
Hokama, S1
Uchida, A1
Sugaya, K1
Zhai, QZ1
Zhang, XX1
Liu, QZ1
de Tacconi, NR1
Chenthamarakshan, CR1
Yogeeswaran, G1
Watcharenwong, A1
de Zoysa, RS1
Basit, NA1
Rajeshwar, K1
Bhambi, M1
Pundir, CS1
Baghel, A1
Singh, B1
Pandey, P1
Sekhar, K1
Marković, V1
Draganić, I1
Holmes, RP1
Petrarulo, M1
Cerelli, E1
Marangella, M1
Cosseddu, D1
Vitale, C1
Linari, F1
Samuelsen, OB1
Campoy Martínez, P1
Reina Ruiz, C1
Salazar Murillo, R1
Quintero Rodríguez, R1
Espinosa Olmedo, FJ1
García Pérez, M1
Hesse, A2
Bongartz, D2
Heynck, H1
Berg, W1
Hönow, R1
Yang, L1
Liu, L1
Olsen, BA1
Nussbaum, MA1
del Nozal, MJ1
Bernal, JL1
Diego, JC1
Gómez, LA1
Ruiz, JM1
Higes, M1
Mesa, MM1
Macías, M1
Cantero, D1
Ensafi, AA2
Kazemzadeh, A1
Abbasi, S1
Rezaei, B1
Izco, JM1
Tormo, M1
Jiménez-Flores, R1
Wilson, DM1
Liedtke, RR1
Wandzilak, TR1
Hagen, LE1
Hughes, H1
Sutton, RA1
Smith, LH1
Williams, HE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Variation in Urine Electrolytes, pH and Specific Gravity Throughout the Day and the Effect of Increased Fluid Intake on Intra-Day Urine Composition[NCT03645785]23 participants (Actual)Interventional2018-08-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Calcium / Creatinine

Ca/Cr at 4 voids throughout the day. Pre = baseline fluid intake; Post = increased fluid and citrate supplementation (NCT03645785)
Timeframe: Day 1 (first void, 9-10 am, 1-2 pm and 5 pm) and Day 4 (first void, 9-10 am, 1-2 pm and 5 pm)

InterventionRatio (Mean)
5pm Void Post0.162234
5p.m. Pre0.161287
1-2 pm Post0.137398
1-2pm Void Pre0.140431
9-10AM Post0.126269
9-10AM Pre0.111446
First Void Pre0.160932
First Void Post0.142987

Citrate/Creatinine Ratio

Citrate/Cr at 4 voids throughout the day. Pre = baseline fluid intake; Post = increased fluid and citrate supplementation (NCT03645785)
Timeframe: Day 1 (first void, 9-10 am, 1-2 pm and 5 pm) and Day 4 (first void, 9-10 am, 1-2 pm and 5 pm)

Interventionratio (Mean)
5pm Void Post0.658644
5p.m. Pre0.584115
1-2 pm Post0.562886
1-2pm Void Pre0.540394
9-10AM Post0.490685
9-10AM Pre0.441938
First Void Pre0.423415
First Void Post0.404892

pH

pH at 4 voids throughout the day. Pre = baseline fluid intake; Post (NCT03645785)
Timeframe: Day 1 (first void, 9-10 am, 1-2 pm and 5 pm) and Day 4 (first void, 9-10 am, 1-2 pm and 5 pm)

InterventionpH (Mean)
5pm Void Post6.52770
5p.m. Pre6.32645
1-2 pm Post6.34060
1-2pm Void Pre6.37845
9-10AM Post6.43430
9-10AM Pre6.24125
First Void Pre6.08345
First Void Post6.01865

Specific Gravity (SG)

SG at 4 voids throughout the day. Pre = baseline fluid intake; Post (NCT03645785)
Timeframe: Day 1 (first void, 9-10 am, 1-2 pm and 5 pm) and Day 4 (first void, 9-10 am, 1-2 pm and 5 pm)

Interventiong/mL (Mean)
5pm Void Post1.01725
5p.m. Pre1.01525
1-2 pm Post1.01725
1-2pm Void Pre1.01850
9-10AM Post1.01950
9-10AM Pre1.02051
First Void Pre1.02000
First Void Post1.01825

Total Fluid Intake

(NCT03645785)
Timeframe: Over 4 day study period

InterventionmL (Mean)
Day 12416.854
Day 22625.093
Day 33116.562
Day 43396.781

Other Studies

31 other studies available for oxalic acid and Sensitivity and Specificity

ArticleYear
Multi-element analysis of milk by ICP-oa-TOF-MS after precipitation of calcium and proteins by oxalic and nitric acid.
    Talanta, 2013, Mar-15, Volume: 106

    Topics: Animals; Calcium; Cations, Divalent; Chemical Precipitation; Milk; Milk Proteins; Nitric Acid; Oxali

2013
Use of urinary concentrations in mg/dl in relation to absolute values in 24-hour samples for the evaluation of lithogenic factors in stone forming patients.
    Archivos espanoles de urologia, 2016, Volume: 69, Issue:2

    Topics: Calcium; Citric Acid; Humans; Hypercalciuria; Magnesium; Oxalic Acid; Risk Factors; Sensitivity and

2016
Use of complexing reagents as additives to the eluent for optimization of separation selectivity in high-performance chelation ion chromatography.
    Journal of chromatography. A, 2008, Dec-05, Volume: 1213, Issue:1

    Topics: Chelating Agents; Chlorides; Chromatography, High Pressure Liquid; Imino Acids; Metals, Heavy; Oxali

2008
Twenty-four hour and spot urine metabolic evaluations: correlations versus agreements.
    Urology, 2010, Volume: 75, Issue:6

    Topics: Adult; Calcium Oxalate; Circadian Rhythm; Citrates; Cohort Studies; Creatinine; Female; Humans; Magn

2010
Specific detection of pathological three-repeat tau after pretreatment with potassium permanganate and oxalic acid in PSP/CBD brains.
    Brain pathology (Zurich, Switzerland), 2011, Volume: 21, Issue:2

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Brain; Female; Humans; Immunohistochemistry; Indicators a

2011
Simultaneous separation of common mono- and divalent cations on an acid-treated silica gel column by ion chromatography with indirect photometric detection and tyramine-oxalic acid, containing 18-crown-6 as eluent.
    Journal of chromatography. A, 2002, May-17, Volume: 956, Issue:1-2

    Topics: Cations, Divalent; Cations, Monovalent; Chromatography, Liquid; Crown Ethers; Ethers, Cyclic; Oxalic

2002
An improved method for production of silica from rice hull ash.
    Bioresource technology, 2002, Volume: 85, Issue:3

    Topics: Acids; Agriculture; Citric Acid; Gels; Hydrochloric Acid; Hydrogen-Ion Concentration; Incineration;

2002
Rapid and convenient determination of oxalic acid employing a novel oxalate biosensor based on oxalate oxidase and SIRE technology.
    Biosensors & bioelectronics, 2003, Aug-15, Volume: 18, Issue:9

    Topics: Biosensing Techniques; Electrochemistry; Flow Injection Analysis; Humans; Oxalic Acid; Oxidoreductas

2003
Ion chromatography with inductively coupled plasma mass spectrometry, a powerful analytical tool for complex matrices estimation of Pt and Pd in environmental samples.
    Journal of chromatography. A, 2003, May-16, Volume: 997, Issue:1-2

    Topics: Anions; Cations; Chromatography; Chromatography, Ion Exchange; Environmental Pollutants; Hydrogen-Io

2003
High-performance liquid chromatographic separation and quantification of citric, lactic, malic, oxalic and tartaric acids using a post-column photochemical reaction and chemiluminescence detection.
    Journal of chromatography. A, 2004, Feb-13, Volume: 1026, Issue:1-2

    Topics: Acids; Animals; Beer; Chromatography, High Pressure Liquid; Citric Acid; Food Analysis; Fruit; Lacti

2004
Oxalic acid alters intracellular calcium in endothelial cells.
    Atherosclerosis, 2004, Volume: 173, Issue:2

    Topics: Biological Transport, Active; Calcium; Calcium Oxalate; Cell Division; Cells, Cultured; Endothelial

2004
Urinary response to an oxalic acid load is influenced by the timing of calcium loading in rats.
    The Journal of urology, 2005, Volume: 174, Issue:5

    Topics: Analysis of Variance; Animals; Calcium; Calcium Oxalate; Dietary Supplements; Disease Models, Animal

2005
Catalytic kinetic spectrophotometry for the determination of trace amount of oxalic acid in biological samples with oxalic acid-rhodamine B-potassium dichromate system.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2006, Volume: 65, Issue:1

    Topics: Catalysis; Indicators and Reagents; Kinetics; Oxalic Acid; Potassium Dichromate; Rhodamines; Sensiti

2006
Nanoporous TiO2 and WO3 films by anodization of titanium and tungsten substrates: influence of process variables on morphology and photoelectrochemical response.
    The journal of physical chemistry. B, 2006, Dec-21, Volume: 110, Issue:50

    Topics: Ammonium Compounds; Electrochemistry; Electrolytes; Fluorides; Glycerol; Mannitol; Membranes, Artifi

2006
Immobilization of grain-sorghum (Sorghum bicolor, var. CSH-14) leaf oxalate oxidase on to a modified mica chip and its application in the determination of urinary oxalate.
    Biotechnology and applied biochemistry, 2007, Volume: 47, Issue:Pt 2

    Topics: Adsorption; Aluminum Silicates; Biosensing Techniques; Coated Materials, Biocompatible; Colorimetry;

2007
A rapid field detection method for arsenic in drinking water.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2007, Volume: 23, Issue:2

    Topics: Acids; Arsenic; Color; Colorimetry; Environmental Monitoring; Filtration; Gold Compounds; Magnesium

2007
New possibilities for routine use of oxalic acid solutions in in-pile dosimetry.
    Radiation research, 1968, Volume: 36, Issue:3

    Topics: Dose-Response Relationship, Radiation; Models, Chemical; Nuclear Reactors; Oxalic Acid; Radiation Do

1968
Measurement of urinary oxalate and citrate by capillary electrophoresis and indirect ultraviolet absorbance.
    Clinical chemistry, 1995, Volume: 41, Issue:9

    Topics: Capillary Action; Citrates; Citric Acid; Electrophoresis; Humans; Hydrogen-Ion Concentration; Kidney

1995
Assay of plasma oxalate with soluble oxalate oxidase.
    Clinical chemistry, 1994, Volume: 40, Issue:11 Pt 1

    Topics: Adolescent; Adsorption; Adult; Ascorbic Acid; Benzenesulfonates; Blood Proteins; Charcoal; Child; Ch

1994
High-performance liquid chromatographic determination of oxolinic acid residues in fish silage.
    Journal of chromatography. B, Biomedical applications, 1994, May-13, Volume: 655, Issue:2

    Topics: Acetonitriles; Animals; Buffers; Chromatography, High Pressure Liquid; Furans; Hydrogen-Ion Concentr

1994
[A metabolic study of urolithiasis. Specificity, sensitivity, efficacy and reproducibility].
    Annales d'urologie, 1995, Volume: 29, Issue:6-7

    Topics: Absorption; Adolescent; Adult; Aged; Calcium; Citrates; Citric Acid; Clinical Protocols; Creatinine;

1995
Measurement of urinary oxalic acid: a comparison of five methods.
    Clinical biochemistry, 1996, Volume: 29, Issue:5

    Topics: Chromatography, Ion Exchange; Costs and Cost Analysis; Humans; Immunoenzyme Techniques; Indicators a

1996
An improved HPLC-enzyme-reactor method for the determination of oxalic acid in complex matrices.
    Clinica chimica acta; international journal of clinical chemistry, 1997, May-28, Volume: 261, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Oxalates; Oxalic Acid; Sensitivity and Specificity

1997
The determination of oxalic acid, oxamic acid, and oxamide in a drug substance by ion-exclusion chromatography.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 22, Issue:3

    Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Drug Contamination; Linear Models; Oxalic

2000
Determination of oxalate, sulfate and nitrate in honey and honeydew by ion-chromatography.
    Journal of chromatography. A, 2000, Jun-09, Volume: 881, Issue:1-2

    Topics: Calibration; Chromatography, Liquid; Fruit; Honey; Nitrates; Oxalic Acid; Sensitivity and Specificit

2000
A simplification of the protein assay method of Ramsay et al. for the quantification of Thiobacillus ferrooxidans in the presence of ferric precipitates.
    Applied microbiology and biotechnology, 2000, Volume: 53, Issue:6

    Topics: Bacterial Proteins; Biomass; Chemical Precipitation; Chemistry Techniques, Analytical; Ferric Compou

2000
Flow injection spectrophotometric determination of ultra trace amounts of oxalic acid.
    Fresenius' journal of analytical chemistry, 2000, Volume: 367, Issue:6

    Topics: Hydrogen-Ion Concentration; Indicators and Reagents; Oxalic Acid; Oxidation-Reduction; Reproducibili

2000
Kinetic spectrophotometric method for the determination of oxalic acid by its catalytic effect on the oxidation of safranine by dichromate.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2001, Volume: 57, Issue:9

    Topics: Calibration; Catalysis; Oxalic Acid; Oxidation-Reduction; Phenazines; Potassium Dichromate; Sensitiv

2001
Development of a CE method to analyze organic acids in dairy products: application to study the metabolism of heat-shocked spores.
    Journal of agricultural and food chemistry, 2002, Mar-27, Volume: 50, Issue:7

    Topics: Acetic Acid; Animals; Butyric Acid; Carboxylic Acids; Citric Acid; Dairy Products; Electrophoresis,

2002
Modified enzyme-based colorimetric assay of urinary and plasma oxalate with improved sensitivity and no ascorbate interference: reference values and sample handling procedures.
    Clinical chemistry, 1991, Volume: 37, Issue:7

    Topics: Adult; Aged; Ascorbic Acid; Chromatography, High Pressure Liquid; Colorimetry; Female; Humans; Male;

1991
Quantitation of glycolate in urine by ion-chromatography.
    Kidney international, 1991, Volume: 39, Issue:4

    Topics: Chromatography, Ion Exchange; Creatinine; Evaluation Studies as Topic; Glycolates; Humans; Oxalates;

1991