An anthrax toxin receptor 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P58335]
Capillary morphogenesis gene 2 protein;
CMG-2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| protocatechuic acid | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| digallic acid | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| gallic acid | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| propyl gallate | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| methyl gallate | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| vanillic acid | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose | Homo sapiens (human) | IC50 | 0.4535 | 2 | 2 |
| epicatechin | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| gallocatechol | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| methyl 3,4-dihydroxybenzoate | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| 3,4-dihydroxyphenylpropionic acid | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| caffeic acid | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| quercetin | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| myricetin | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| tannins | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
| metal ion binding | molecular function | Binding to a metal ion. [GOC:ai] |
| transmembrane signaling receptor activity | molecular function | Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. [GOC:go_curators, Wikipedia:Transmembrane_receptor] |
This protein is located in 4 target(s):
| Target | Category | Definition |
|---|---|---|
| extracellular region | cellular component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
| endoplasmic reticulum membrane | cellular component | The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah] |
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| endosome membrane | cellular component | The lipid bilayer surrounding an endosome. [GOC:mah] |
This protein is active in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| cell surface | cellular component | The external part of the cell wall and/or plasma membrane. [GOC:jl, GOC:mtg_sensu, GOC:sm] |