Compounds > trifloxystrobin
Page last updated: 2024-12-11

trifloxystrobin

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Description

trifloxystrobin : The methyl ester of (2E)-(methoxyimino)[2-({[(E)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetic acid. A foliar applied fungicide for cereals which is particularly active against Ascomycetes, Deuteromycetes and Oomycetes [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID53627428
SCHEMBL ID4448910
MeSH IDM0440810
PubMed CID11664966
CHEMBL ID1897483
CHEBI ID81833
SCHEMBL ID9880011
SCHEMBL ID19148

Synonyms (48)

Synonym
trifloxystrobin
141517-21-7
cga 279202
SCHEMBL4448910
c20h19f3n2o4
C72628
(e)-methyl 2-(methoxyimino)-2-(2-((((e)-(1-(3-(trifluoromethyl)phenyl)ethylidene)amino)oxy)methyl)phenyl)acetate
methyl (e)-2-(methoxyimino)-2-(2-(((((e)-1-(3-(trifluoromethyl)phenyl)ethylidene)amino)oxy)methyl)phenyl)acetate
Q15090829
methyl (z,z)-alpha-(methoxyimino)-2-[({1-[3- (trifluoromethyl)phenyl]ethylidene}amino)oxy]methyl]benzeneacetate
trifloxystrobin 1000 microg/ml in toluene
EN300-6486649
methyl (2z)-2-(methoxyimino)-2-[2-({[(z)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetate
methyl (2z)-(methoxyimino)[2-({[(z)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetate
DTXSID701024921
711603-62-2
NCGC00163847-01
methyl (2e)-(methoxyimino)(2-{[({(1e)-1-[3-(trifluoromethyl)phenyl]ethylidene}amino)oxy]methyl}phenyl)acetate
NCGC00163847-02
SCHEMBL9880011
methyl (2e)-2-methoxyimino-2-[2-[[(z)-1-[3-(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate
A807769
(2e)-2-methoxyimino-2-[2-[[(e)-1-[3-(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetic acid methyl ester
methyl (2e)-2-methoxyimino-2-[2-[[(e)-1-[3-(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]ethanoate
NCGC00163847-03
C18562
dtxsid4032580 ,
SCHEMBL19148
CHEMBL1897483
chebi:81833 ,
methyl methoxyimino(alpha-(1-(alpha,alpha,alpha-trifluoro-3-tolyl)ethylideneaminooxy)-2-tolyl)acetate
methyl (alphae)-alpha-(methoxyimino)-2-[[[[(1e)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]oxy]methyl]benzeneacetate
methyl (e)-methoxyimino-{(e)-alpha-[1-(alpha,alpha,alpha-trifluoro-m-tolyl)ethylideneaminooxy]-o-tolyl}acetate
methyl (2e)-(methoxyimino)[2-({[(e)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetate
trifloxystrobin, pestanal(r), analytical standard
ONCZDRURRATYFI-TVJDWZFNSA-N ,
J-007507
methyl (2e)-2-methoxyimino-2-[2-[[(e)-1-[3-(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate
AKOS030621531
AMY14810
CS-0082159
HY-123230
benzeneacetic acid, alpha-(methoxyimino)-2-[[[(e)-[1-[3-(trifluoromethyl)phenyl]ethylidene]amino]oxy]methyl]-, methyl ester, (alphae)-
methyl (e)-alpha-methoxyimino-2-[(e)-1-(3-trifluoromethylphenyl)ethylidenaminooxymethyl]phenylacetate
benzeneacetic acid, a-(methoxyimino)-2-[[[(e)-[1-[3-(trifluoromethyl)phenyl]ethylidene]amino]oxy]methyl]-, methyl ester, (ae)-
AS-76139
EN300-6486651
methyl (2e)-2-(methoxyimino)-2-[2-({[(e)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetate

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The present study reinforces previous studies that Headline and Stratego are toxic to nontarget aquatic organisms."( Acute toxicity of pyraclostrobin and trifloxystrobin to Hyalella azteca.
Belden, JB; McMurry, ST; Morrison, SA; Smith, LM, 2013)		0.39
" Our results suggest that TFS is highly toxic to fish embryos."( Assessment of trifloxystrobin uptake kinetics, developmental toxicity and mRNA expression in rare minnow embryos.
Ling, F; Liu, GL; Liu, L; Wang, GX; Zhu, B, 2015)		0.42
"Strobilurins have been reported highly toxic to non-target aquatic organisms but few illustrated how they cause toxic effects on algae."( Acute toxicity and associated mechanisms of four strobilurins in algae.
Chen, H; Li, X; Liu, X; Pang, S; Wang, C; Wang, Y; Zhang, J, 2018)		0.48
" However, its adverse effects on aquatic organisms remain unknown."( Low trifloxystrobin-tebuconazole concentrations induce cardiac and developmental toxicity in zebrafish by regulating notch mediated-oxidative stress generation.
Chen, G; Guo, C; Jia, K; Liao, X; Liu, F; Lu, H; Luo, J; Xiong, G; Zeng, J, 2022)		0.72
" The toxic effects of TFS were tested, considering physiological, cytogenetic, biochemical and anatomical analyses."( Acute multiple toxic effects of Trifloxystrobin fungicide on Allium cepa L.
Çavuşoğlu, K; Kalefetoğlu Macar, T; Macar, O; Yalçın, E, 2022)		0.72

Compound-Compound Interactions

ExcerptReferenceRelevance
" A simple and sensitive liquid chromatography-ultraviolet detection (LC-UV) method combined with the 'Quick Easy Cheap Effective Rugged and Safe' (QuEChERS) protocol was developed to quantify the levels of kresoxim-methyl and trifloxystrobin residues in citrus."( Simultaneous detection and degradation patterns of kresoxim-methyl and trifloxystrobin residues in citrus fruits by HPLC combined with QuEChERS.
Dai, XJ; Fang, JJ; Zhu, HM; Zhu, J, 2013)		0.39
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
mitochondrial cytochrome-bc1 complex inhibitornull
antifungal agrochemicalAny substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
oxime O-etherO-organyl oximes R2C=NOR' (R' =/= H).
organofluorine compoundAn organofluorine compound is a compound containing at least one carbon-fluorine bond.
methyl esterAny carboxylic ester resulting from the formal condensation of a carboxy group with methanol.
methoxyiminoacetate strobilurin antifungal agent
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (10)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency14.12540.000221.22318,912.5098AID588516
retinoid X nuclear receptor alphaHomo sapiens (human)Potency24.06820.000817.505159.3239AID588544; AID588546
farnesoid X nuclear receptorHomo sapiens (human)Potency25.11890.375827.485161.6524AID588526
pregnane X nuclear receptorHomo sapiens (human)Potency31.62280.005428.02631,258.9301AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency25.48900.000229.305416,493.5996AID588513; AID588514
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency35.48130.001019.414170.9645AID588536; AID588537
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency35.48130.023723.228263.5986AID588541
aryl hydrocarbon receptorHomo sapiens (human)Potency63.09570.000723.06741,258.9301AID651777
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency8.63490.000627.21521,122.0200AID651741
Cellular tumor antigen p53Homo sapiens (human)Potency5.01190.002319.595674.0614AID651743
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (124)

Processvia Protein(s)Taxonomy
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycle G2/M phase transitionCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
ER overload responseCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
mitophagyCellular tumor antigen p53Homo sapiens (human)
in utero embryonic developmentCellular tumor antigen p53Homo sapiens (human)
somitogenesisCellular tumor antigen p53Homo sapiens (human)
release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
hematopoietic progenitor cell differentiationCellular tumor antigen p53Homo sapiens (human)
T cell proliferation involved in immune responseCellular tumor antigen p53Homo sapiens (human)
B cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
T cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
response to ischemiaCellular tumor antigen p53Homo sapiens (human)
nucleotide-excision repairCellular tumor antigen p53Homo sapiens (human)
double-strand break repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
protein import into nucleusCellular tumor antigen p53Homo sapiens (human)
autophagyCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorCellular tumor antigen p53Homo sapiens (human)
transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
Ras protein signal transductionCellular tumor antigen p53Homo sapiens (human)
gastrulationCellular tumor antigen p53Homo sapiens (human)
neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
protein localizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA replicationCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
determination of adult lifespanCellular tumor antigen p53Homo sapiens (human)
mRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
rRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
response to salt stressCellular tumor antigen p53Homo sapiens (human)
response to inorganic substanceCellular tumor antigen p53Homo sapiens (human)
response to X-rayCellular tumor antigen p53Homo sapiens (human)
response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
positive regulation of gene expressionCellular tumor antigen p53Homo sapiens (human)
cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
viral processCellular tumor antigen p53Homo sapiens (human)
glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
cerebellum developmentCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell growthCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
mitotic G1 DNA damage checkpoint signalingCellular tumor antigen p53Homo sapiens (human)
negative regulation of telomere maintenance via telomeraseCellular tumor antigen p53Homo sapiens (human)
T cell differentiation in thymusCellular tumor antigen p53Homo sapiens (human)
tumor necrosis factor-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
regulation of tissue remodelingCellular tumor antigen p53Homo sapiens (human)
cellular response to UVCellular tumor antigen p53Homo sapiens (human)
multicellular organism growthCellular tumor antigen p53Homo sapiens (human)
positive regulation of mitochondrial membrane permeabilityCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
entrainment of circadian clock by photoperiodCellular tumor antigen p53Homo sapiens (human)
mitochondrial DNA repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
transcription initiation-coupled chromatin remodelingCellular tumor antigen p53Homo sapiens (human)
negative regulation of proteolysisCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of RNA polymerase II transcription preinitiation complex assemblyCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
response to antibioticCellular tumor antigen p53Homo sapiens (human)
fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
circadian behaviorCellular tumor antigen p53Homo sapiens (human)
bone marrow developmentCellular tumor antigen p53Homo sapiens (human)
embryonic organ developmentCellular tumor antigen p53Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationCellular tumor antigen p53Homo sapiens (human)
protein stabilizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of helicase activityCellular tumor antigen p53Homo sapiens (human)
protein tetramerizationCellular tumor antigen p53Homo sapiens (human)
chromosome organizationCellular tumor antigen p53Homo sapiens (human)
neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
hematopoietic stem cell differentiationCellular tumor antigen p53Homo sapiens (human)
negative regulation of glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
type II interferon-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
cardiac septum morphogenesisCellular tumor antigen p53Homo sapiens (human)
positive regulation of programmed necrotic cell deathCellular tumor antigen p53Homo sapiens (human)
protein-containing complex assemblyCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressCellular tumor antigen p53Homo sapiens (human)
thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
necroptotic processCellular tumor antigen p53Homo sapiens (human)
cellular response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
cellular response to xenobiotic stimulusCellular tumor antigen p53Homo sapiens (human)
cellular response to ionizing radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to UV-CCellular tumor antigen p53Homo sapiens (human)
stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
cellular response to actinomycin DCellular tumor antigen p53Homo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
cellular senescenceCellular tumor antigen p53Homo sapiens (human)
replicative senescenceCellular tumor antigen p53Homo sapiens (human)
oxidative stress-induced premature senescenceCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
oligodendrocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of execution phase of apoptosisCellular tumor antigen p53Homo sapiens (human)
negative regulation of mitophagyCellular tumor antigen p53Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of G1 to G0 transitionCellular tumor antigen p53Homo sapiens (human)
negative regulation of miRNA processingCellular tumor antigen p53Homo sapiens (human)
negative regulation of glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
negative regulation of pentose-phosphate shuntCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
regulation of fibroblast apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
positive regulation of cellular senescenceCellular tumor antigen p53Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (34)

Processvia Protein(s)Taxonomy
transcription cis-regulatory region bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
core promoter sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
TFIID-class transcription factor complex bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
protease bindingCellular tumor antigen p53Homo sapiens (human)
p53 bindingCellular tumor antigen p53Homo sapiens (human)
DNA bindingCellular tumor antigen p53Homo sapiens (human)
chromatin bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activityCellular tumor antigen p53Homo sapiens (human)
mRNA 3'-UTR bindingCellular tumor antigen p53Homo sapiens (human)
copper ion bindingCellular tumor antigen p53Homo sapiens (human)
protein bindingCellular tumor antigen p53Homo sapiens (human)
zinc ion bindingCellular tumor antigen p53Homo sapiens (human)
enzyme bindingCellular tumor antigen p53Homo sapiens (human)
receptor tyrosine kinase bindingCellular tumor antigen p53Homo sapiens (human)
ubiquitin protein ligase bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase regulator activityCellular tumor antigen p53Homo sapiens (human)
ATP-dependent DNA/DNA annealing activityCellular tumor antigen p53Homo sapiens (human)
identical protein bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase bindingCellular tumor antigen p53Homo sapiens (human)
protein heterodimerization activityCellular tumor antigen p53Homo sapiens (human)
protein-folding chaperone bindingCellular tumor antigen p53Homo sapiens (human)
protein phosphatase 2A bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingCellular tumor antigen p53Homo sapiens (human)
14-3-3 protein bindingCellular tumor antigen p53Homo sapiens (human)
MDM2/MDM4 family protein bindingCellular tumor antigen p53Homo sapiens (human)
disordered domain specific bindingCellular tumor antigen p53Homo sapiens (human)
general transcription initiation factor bindingCellular tumor antigen p53Homo sapiens (human)
molecular function activator activityCellular tumor antigen p53Homo sapiens (human)
promoter-specific chromatin bindingCellular tumor antigen p53Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (19)

Processvia Protein(s)Taxonomy
nuclear bodyCellular tumor antigen p53Homo sapiens (human)
nucleusCellular tumor antigen p53Homo sapiens (human)
nucleoplasmCellular tumor antigen p53Homo sapiens (human)
replication forkCellular tumor antigen p53Homo sapiens (human)
nucleolusCellular tumor antigen p53Homo sapiens (human)
cytoplasmCellular tumor antigen p53Homo sapiens (human)
mitochondrionCellular tumor antigen p53Homo sapiens (human)
mitochondrial matrixCellular tumor antigen p53Homo sapiens (human)
endoplasmic reticulumCellular tumor antigen p53Homo sapiens (human)
centrosomeCellular tumor antigen p53Homo sapiens (human)
cytosolCellular tumor antigen p53Homo sapiens (human)
nuclear matrixCellular tumor antigen p53Homo sapiens (human)
PML bodyCellular tumor antigen p53Homo sapiens (human)
transcription repressor complexCellular tumor antigen p53Homo sapiens (human)
site of double-strand breakCellular tumor antigen p53Homo sapiens (human)
germ cell nucleusCellular tumor antigen p53Homo sapiens (human)
chromatinCellular tumor antigen p53Homo sapiens (human)
transcription regulator complexCellular tumor antigen p53Homo sapiens (human)
protein-containing complexCellular tumor antigen p53Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (80)

Assay IDTitleYearJournalArticle
AID1112709Antifungal activity against Cercospora beticola isolate 11-1006-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112715Antifungal activity against Cercospora beticola isolate 11-1015-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112722Antifungal activity against Cercospora beticola isolate 11-1027-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112694Antifungal activity against Cercospora beticola isolate 11-1044-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104842Antifungal activity against Erysiphe necator biotype B assessed as AUDPC at 0.625 g a.i./l applied 4 days post-inoculation measured after 14 days during cycle 2 by leaf-disk method (Rvb = 844)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112537Antifungal activity against Botryotinia fuckeliana SAS56 assessed as inhibition of colony growth2012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112536Antifungal activity against Botryotinia fuckeliana SAS405 assessed as inhibition of colony growth2012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112736Antifungal activity against Cercospora beticola isolate 11-1041-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112533Antifungal activity against QoI fungicide-resistant Botryotinia fuckeliana field isolates expressing cytb G143A mutant gene assessed as inhibition of colony growth2012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112531Resistance index, ratio of EC50 for QoI fungicide-resistant Botryotinia fuckeliana field isolates expressing cytb G143A mutant gene to EC50 for Botryotinia fuckeliana SAS4052012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112710Antifungal activity against Cercospora beticola isolate 11-1007-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112735Antifungal activity against Cercospora beticola isolate 11-1040-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112720Antifungal activity against Cercospora beticola isolate 11-1026-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112535Antifungal activity against Botryotinia fuckeliana SAS56 assessed as complete inhibition of colony growth at 1 mg/ml2012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1104856Antifungal activity against Erysiphe necator biotype B assessed as number of spores at 0.625 g a.i./l applied 48 hr post-inoculation measured after 14 days by leaf-disk method (Rvb = 43.5 x 10'3 cm'-2)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1104835Antifungal activity against Erysiphe necator biotype B assessed as disease severity at 0.625 g a.i./l applied 4 days post-inoculation measured immediately during cycle 1 by leaf-disk method relative to untreated-control2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112707Antifungal activity against Cercospora beticola isolate 11-1005-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112716Antifungal activity against Cercospora beticola isolate 11-1015-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1080373Fungicidal activity against Botryotinia fuckeliana assessed as inhibition of mycelial growth at 25 mg/ml measured after 48 hr2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins.
AID1112725Antifungal activity against Cercospora beticola isolate 11-1028-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112528Resistance index, ratio of EC50 for QoI fungicide-resistant Botryotinia fuckeliana lab isolates to EC50 for Botryotinia fuckeliana SAS4052012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112691Antifungal activity against Cercospora beticola isolate 11-1046-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104841Antifungal activity against Erysiphe necator biotype B assessed as number of spores at 0.625 g a.i./l applied 4 days post-inoculation measured after 14 days during cycle 2 by leaf-disk method (Rvb = 44.4 x 10'3 cm'-2)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112714Antifungal activity against Cercospora beticola isolate 11-1014-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112734Antifungal activity against Cercospora beticola isolate 11-1040-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104857Antifungal activity against Erysiphe necator biotype B assessed as AUDPC at 0.625 g a.i./l applied 48 hr post-inoculation measured after 14 days by leaf-disk method (Rvb = 394)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1104823Antifungal activity against Erysiphe necator biotype B assessed as AUDPC at 0.625 g a.i./l applied 13 days post-inoculation measured after 14 days during cycle 2 by leaf-disk method (Rvb = 654)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1080370Fungicidal activity against Colletotrichum lagenaria infected in compound pre-treated cucumber plants assessed as inhibition of fungal growth at 6.25 mg/ml measured 3 days post compound treatment2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins.
AID1112726Antifungal activity against Cercospora beticola isolate 11-1035-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112702Antifungal activity against Cercospora beticola isolate 98-150-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112696Antifungal activity against Cercospora beticola isolate 98-9-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104851Antifungal activity against Erysiphe necator biotype B assessed as disease severity at 0.625 g a.i./l applied 48 hr post-inoculation measured after 7 days by leaf-disk method relative to untreated-control2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112712Antifungal activity against Cercospora beticola isolate 11-1008-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112717Antifungal activity against Cercospora beticola isolate 11-1016-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112708Antifungal activity against Cercospora beticola isolate 11-1005-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112532Resistance index, ratio of EC50 for QoI fungicide-resistant Botryotinia fuckeliana field isolates expressing cytb G143A mutant gene to EC50 for Botryotinia fuckeliana SAS562012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112718Antifungal activity against Cercospora beticola isolate 11-1022-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112699Antifungal activity against Cercospora beticola isolate 98-13-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112737Antifungal activity against Cercospora beticola isolate 11-1042-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112703Antifungal activity against Cercospora beticola isolate 99-233-3-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1091311Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 6.2 ppm measured after 1 or 2 weeks2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
Synthesis and fungicidal activities of novel bis(trifluoromethyl)phenyl-based strobilurins.
AID1112693Antifungal activity against Cercospora beticola isolate 11-1045-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112698Antifungal activity against Cercospora beticola isolate 98-12-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104843Antifungal activity against Erysiphe necator biotype B assessed as number of spores at 0.625 g a.i./l applied 4 days post-inoculation measured after 14 days during cycle 1 by leaf-disk method (Rvb = 35.9 x 10'3 cm'-2)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112727Antifungal activity against Cercospora beticola isolate 11-1036-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112733Antifungal activity against Cercospora beticola isolate 11-1039-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112729Antifungal activity against Cercospora beticola isolate 11-1037-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112706Antifungal activity against Cercospora beticola isolate 11-1004-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112738Antifungal activity against Cercospora beticola isolate 11-1042-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112695Antifungal activity against Cercospora beticola isolate 11-1044-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112721Antifungal activity against Cercospora beticola isolate 11-1026-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112697Antifungal activity against Cercospora beticola isolate 98-10-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112731Antifungal activity against Cercospora beticola isolate 11-1038-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112728Antifungal activity against Cercospora beticola isolate 11-1036-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1080372Fungicidal activity against Pseudoperonospora cubensis grown on compound pre-treated cucumber leaves assessed as inhibition of fungal growth at 6.25 mg/ml measured 5 days post compound treatment2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins.
AID1080371Fungicidal activity against Blumeria graminis grown on compound pre-treated wheat seedlings assessed as inhibition of fungal growth at 6.25 mg/ml measured 7 days post fungal inoculation2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins.
AID1112719Antifungal activity against Cercospora beticola isolate 11-1022-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112732Antifungal activity against Cercospora beticola isolate 11-1038-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1091312Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 500 ppm measured after 1 or 2 weeks2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
Synthesis and fungicidal activities of novel bis(trifluoromethyl)phenyl-based strobilurins.
AID1112701Antifungal activity against Cercospora beticola isolate 98-101-5-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112705Antifungal activity against Cercospora beticola isolate 11-1003-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104822Antifungal activity against Erysiphe necator biotype B assessed as number of spores at 0.625 g a.i./l applied 13 days post-inoculation measured after 14 days during cycle 2 by leaf-disk method (Rvb = 47.6 x 10'3 cm'-2)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112692Antifungal activity against Cercospora beticola isolate 11-1046-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112724Antifungal activity against Cercospora beticola isolate 11-1028-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1091309Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 1.5 ppm measured after 1 or 2 weeks2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
Synthesis and fungicidal activities of novel bis(trifluoromethyl)phenyl-based strobilurins.
AID1112730Antifungal activity against Cercospora beticola isolate 11-1037-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1091310Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 3.1 ppm measured after 1 or 2 weeks2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
Synthesis and fungicidal activities of novel bis(trifluoromethyl)phenyl-based strobilurins.
AID1112711Antifungal activity against Cercospora beticola isolate 11-1007-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112530Antifungal activity against QoI fungicide-resistant Botryotinia fuckeliana lab isolates assessed as inhibition of colony growth2012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1112739Antifungal activity against Cercospora beticola isolate 11-1043-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112713Antifungal activity against Cercospora beticola isolate 11-1009-1 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1080375Fungicidal activity against Magnaporthe oryzae assessed as inhibition of mycelial growth at 25 mg/ml measured after 48 hr2008Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins.
AID1112704Antifungal activity against Cercospora beticola isolate 99-521-29-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112723Antifungal activity against Cercospora beticola isolate 11-1027-2 expressing cytb with alanine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1104850Antifungal activity against Erysiphe necator biotype B assessed as disease severity at 0.625 g a.i./l applied 48 hr post-inoculation measured after 14 days by leaf-disk method relative to untreated-control2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1112700Antifungal activity against Cercospora beticola isolate 98-19-M expressing cytb with glycine at codon 143 assessed as reduction in spore germination2013Pest management science, Jan, Volume: 69, Issue:1
Identification of the G143A mutation associated with QoI resistance in Cercospora beticola field isolates from Michigan, United States.
AID1112529Resistance index, ratio of EC50 for QoI fungicide-resistant Botryotinia fuckeliana lab isolates to EC50 for Botryotinia fuckeliana SAS562012Pest management science, Sep, Volume: 68, Issue:9
Genetic analysis and molecular characterisation of laboratory and field mutants of Botryotinia fuckeliana (Botrytis cinerea) resistant to QoI fungicides.
AID1104831Antifungal activity against Erysiphe necator biotype B assessed as disease severity at 0.625 g a.i./l applied 4 days post-inoculation measured after 14 days during cycle 1 by leaf-disk method relative to untreated-control2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1104844Antifungal activity against Erysiphe necator biotype B assessed as AUDPC at 0.625 g a.i./l applied 4 days post-inoculation measured after 14 days during cycle 1 by leaf-disk method (Rvb = 695.6)2010Pest management science, Dec, Volume: 66, Issue:12
Efficacy of fungicides with various modes of action in controlling the early stages of an Erysiphe necator-induced epidemic.
AID1091313Fungicidal activity against Blumeria graminis infected compound pre-treated wheat plants assessed as disease preventive activity at 100 ppm measured after 1 or 2 weeks2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
Synthesis and fungicidal activities of novel bis(trifluoromethyl)phenyl-based strobilurins.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (100)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's21 (21.00)29.6817
2010's56 (56.00)24.3611
2020's23 (23.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Trials0 (0.00%)5.53%
Reviews1 (1.01%)6.00%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other98 (98.99%)84.16%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetic acid
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.		2.2510monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
carbamates
[no description available]		4.7990amino-acid anion
niacinamide
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.		2.1310pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
atrazine
[no description available]		2.2510chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
iodoquinol
Iodoquinol: One of the halogenated 8-quinolinols widely used as an intestinal antiseptic, especially as an antiamebic agent. It is also used topically in other infections and may cause CNS and eye damage. It is known by very many similar trade names world-wide.. iodoquinol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.		2.2510monohydroxyquinoline;
organoiodine compound		antiamoebic agent;
antibacterial agent;
antiprotozoal drug;
antiseptic drug
metolachlor
metolachlor: structure given in first source. metolachlor : A racemate that consists of equimolar amounts of (R)- and (S)-metolachlor.. 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide : An organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl) group at the nitrogen atom.		2.2510aromatic amide;
benzenes;
ether;
organochlorine compound
alanine
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.		2.0510alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
acetonitrile
acetonitrile: RN given refers to unlabeled cpd. acetonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.		2.5120aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
phencyclidine
Phencyclidine: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.. phencyclidine : A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.		2.2510benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
captan
Captan: One of the phthalimide fungicides.. captan : A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.		7.7830isoindoles;
organochlorine compound;
organosulfur compound;
phthalimide fungicide		antifungal agrochemical
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		2.73301,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
aminoimidazole carboxamide
Aminoimidazole Carboxamide: An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.. 5-aminoimidazole-4-carboxamide : An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.		2.4820aminoimidazole;
monocarboxylic acid amide		mouse metabolite
hydantoins
Hydantoins: Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.. imidazolidine-2,4-dione : An imidazolidinone with oxo groups at position 2 and 4.		2.4820imidazolidine-2,4-dione
malondialdehyde
Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.		3.0430dialdehydebiomarker
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide
N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide: an endocrine disruptor; structure given in first source. tolylfluanid : A member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union.		2.1310organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides		antifungal agrochemical;
genotoxin
tetrachloroisophthalonitrile
tetrachloroisophthalonitrile: structure. chlorothalonil : A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops.		3.2250aromatic fungicide;
dinitrile;
tetrachlorobenzene		antifungal agrochemical
fluorescein
Fluorescein: A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.. fluorescein (lactone form) : A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.		2.15102-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
carbendazim
carbendazim: carcinogen when combined with sodium nitrite; principle metabolite of thiophanate methyl & benomyl; structure. carbendazim : A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables.		2.1110benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		7.02910benzenes;
phenyl acetates
pronamide
pronamide: structure. propyzamide : A member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops.		2.1310benzamides;
dichlorobenzene;
terminal acetylenic compound		agrochemical;
herbicide
enilconazole
enilconazole: RN given refers to parent cpd. enilconazole : A racemate comprising equimolar amounts of (R)- and (S)-enilconazole. A fungicide used to control a wide range of fungi including Tilletia and Helminthosporium spp. on fruit, vegetables and ornamentals. In veterinary medicine, it is used topically for the treatment of fungal skin infections in cattle, dogs, and horses; it is also used by inhalation for the treatment of aspergillosis in ostriches.. 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a 2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl group.		2.4620dichlorobenzene;
ether;
imidazoles
iprodione
iprodione : An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide.		2.4820benzenes;
dichlorophenyl dicarboximide fungicide;
imidazole fungicide;
imidazolidine-2,4-dione;
ureas		antifungal agrochemical;
nematicide
metalaxyl
metalaxyl: RN given refers to (DL-Ala)-isomer. metalaxyl : A racemate comprising equal amounts of (R)- and (S)-metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.. methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate : An alanine derivative that is methyl alaninate in which one of the hydrogens attached to the nitrogen is substituted by a methoxyacetyl group, while the other is substituted by a 2,6-dimethylphenyl group.		2.0510alanine derivative;
aromatic amide;
carboxamide;
ether;
methyl ester
propiconazole
Orbit: Bony cavity that holds the eyeball and its associated tissues and appendages.		3.8330conazole fungicide;
cyclic ketal;
dichlorobenzene;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		5.872801,2,3-triazole
buparvaquone
buparvaquone: used in therapy of theileriasis; structure given in first source		7.4110
tebuconazole
Lynx: A genus in the family FELIDAE comprising felines with long legs, ear tufts, and a short tail.. 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol : A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively.. tebuconazole : A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops.		4.5210monochlorobenzenes;
tertiary alcohol;
triazoles
spiroxamine
spiroxamine: structure in first source. spiroxamine : The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes.		2.0510dioxolane;
spiroketal;
tertiary amino compound		antifungal agrochemical;
environmental contaminant;
sterol biosynthesis inhibitor;
xenobiotic
difenoconazole
difenoconazole : A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms.		8.0840aromatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
cyprodinil
cyprodinil: structure in first source. cyprodinil : A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as well as most aquatic organisms and earthworms, but it is not considered toxic to honeybees.		2.5220aminopyrimidine;
anilinopyrimidine fungicide;
cyclopropanes;
secondary amino compound		antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
pyrimethanil
pyrimethanil: structure in first source. pyrimethanil : A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine.		2.1310aminopyrimidine;
anilinopyrimidine fungicide;
secondary amino compound		antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
bitertanol
bitertanol: a triazole fungicide; structure given in first source. bitertanol : A diastereoisomeric mixture composed of the enantiomeric pair (1R,2S)- and (1S,2R)-bitertanol in a 4:1 ratio with the enantiomeric pair (1R,2R)- and (1S,2S)-bitertanol. A fungicide used to control a range of diseases including scab, powder mildew, rusts and blackspot. It is moderately toxic to most animal and insect species but is non-toxic to honeybees.. 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol : A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O-1 by a biphenyl-4-yl group.		2.2510aromatic ether;
biphenyls;
secondary alcohol;
triazoles
diflufenican
diflufenican : A pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2.		2.1310(trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
fenpropimorph
[no description available]		2.0110alkylbenzene
thiacloprid
thiacloprid: structure in first source. (Z)-thiacloprid : The (Z)-stereoisomer of thiacloprid.. thiacloprid : A nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen.		7.3110monochloropyridine;
nitrile;
thiazolidines		environmental contaminant;
neonicotinoid insectide;
xenobiotic
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide: structure in first source. fenhexamid : An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol.		2.4420anilide fungicide;
aromatic amide;
dichlorobenzene;
monocarboxylic acid amide;
phenols		antifungal agrochemical;
EC 1.14.13.72 (methylsterol monooxygenase) inhibitor;
sterol biosynthesis inhibitor
famoxadone
famoxadone: strobilurin analogue; structure in first source. famoxadone : A racemate composed of equimolar amounts of (R)- and (S)-famoxadone. It prevents spore germination and mycelial growth of sensitive fungi, and is used in agriculture for the control of various fungal diseases. Only the (S)- enantiomer is active.. 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione : A member of the class of oxazolidinones that is 1,3-oxazolidine-2,4-dione in which the hydrogen attached to the nitrogen is substituted by a phenylamino group and the hydrogens at position 5 are substituted by methyl and 4-phenoxyphenyl groups.		2.7330aromatic ether;
carbohydrazide;
oxazolidinone
betadex
beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.		2.1110cyclodextrin
nabam
mancozeb: complex of zinc & maneb, containing 20% manganese & 2.5% zinc. mancozeb : A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide.. ethylenebis(dithiocarbamic acid) : A dithiocarbamic acid resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine.		2.0510dithiocarbamic acids
zineb
Zineb: An agricultural fungicide of the dithiocarbamate class. It has relatively low toxicity and there is little evidence of human injury from exposure.. zineb : A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU.		2.0510dithiocarbamate salt;
macromolecule;
zinc coordination entity		antifungal agrochemical
maneb
Maneb: Manganese derivative of ethylenebisdithiocarbamate. It is used in agriculture as a fungicide and has been shown to cause irritation to the eyes, nose, skin, and throat.. maneb : A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab.		2.0510
azoxystrobin
azoxystrobin: a methoxyacrylate analog; a strobilurin fungicide; structure given in first source. azoxystrobin : An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.		5.33160aryloxypyrimidine;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
methyl ester;
nitrile		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
quinone outside inhibitor;
xenobiotic
epoxiconazole
epoxiconazole : A racemate composed of equimolar amounts of (2S,3R)- and (2R,3S)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms.. 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole : An epoxide that is oxirane substituted by a 2-chlorophenyl, 4-fluorophenyl and a 1H-1,2,4-triazol-1-ylmethyl groups.		2.0110epoxide;
monochlorobenzenes;
monofluorobenzenes;
triazoles
quinoxyfen
quinoxyfen: structure in first source. quinoxyfen : A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.		2.0510aromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines		antifungal agrochemical
zearalenone
Zearalenone: (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.. zearalenone : A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.		7.610macrolide;
resorcinols		fungal metabolite;
mycoestrogen
cyhalothrin
cyhalothrin: acaricidal & insecticidal synthetic pyrethroid; structure given in first source. cyhalothrin : A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.		2.1710aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
dimethomorph
dimethomorph: structure given in first source; RN given refers to cpd without isomeric designation. (Z)-dimethomorph : An enamide resulting from the formal condensation of (2Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid with the amino group of morpholine. The agricultural fungicide dimethomorph is a mixture of (E)- and (Z)-dimethomorph; only the Z isomer has fungicidal activity.. dimethomorph : A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity.		2.1310aromatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide
propineb
propineb: structure. propineb : A polymeric complex of zinc with the propylene 1,2-bis(dithiocarbamate) anionic ligand. A fungicide, it is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grapes, tomatoes, potatoes, berries, citrus, rice and tea.		7.610dithiocarbamate salt;
macromolecule;
zinc coordination entity		antifungal agrochemical
kresoxim-methyl
kresoxim-methyl: strobilurin analogue; an industrial fungicide. kresoxim-methyl : A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.		4.33180aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
pyrachlostrobin
pyraclostrobin : A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres.		5.38160aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
prothioconazole
prothioconazole: a fungicide. prothioconazole : A racemate comprising equal amounts of (R)- and (S)-prothioconazole. A fungicide for use both as a seed treatment and foliar spray to treat a variety of diseases in cereals.. 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione : A member of the class of triazoles that is 1,2,4-triazole-3-thione substituted at position 2 by a 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl group.		2.8630cyclopropanes;
monochlorobenzenes;
tertiary alcohol;
thiocarbonyl compound;
triazoles
mocetinostat
mocetinostat: undergoing phase II clinical trials for treatment of cancer. mocetinostat : A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).		2.5220aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
fenamidone
fenamidone: a fungicide against downy mildew; structure in first source. fenamidone : A member of the class of imidazolones that is 3,5-dihydroimidazol-4-one substituted at position 2 by a methylthiogroup, at position 3 by an anilino group and at position 5 by phenyl and methyl groups (the S-enantiomer). A fungicide effective against Oomycete diseases such as downy mildew and certain leaf spot diseases.		2.0510carbohydrazide;
imidazole fungicide;
imidazolone;
organic sulfide		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor;
quinone outside inhibitor
fluoxastrobin
fluoxastrobin: a fungicide. fluoxastrobin : An oxime O-ether that is the O-methyl oxime of (2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone. A fungicide used for disease control of potatoes and a wide range of vegetables.		2.2510aromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
picoxystrobin
picoxystrobin: a fungicide. picoxystrobin : An enoate ester that is the methyl ester of (2E)-3-methoxy-2-[2-({[6-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]prop-2-enoic acid. A cereal fungicide used to control a wide range of diseases including brown rust, tan spot, powdery mildew and net blotch.		3.5270aromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
fluxapyroxad
fluxapyroxad: carboxamide; succinate dehydrogenase inhibitor. fluxapyroxad : An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families.		2.1710anilide fungicide;
aromatic amide;
biphenyls;
pyrazoles;
trifluorobenzene		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
chlorophyll a
Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.		2.0110chlorophyll;
methyl ester		cofactor
piperidines
Piperidines: A family of hexahydropyridines.		2.1310
pyrethrins
[no description available]		2.1710
mitotempo
MitoTEMPO: an antioxidant		2.1310
tebuconazole
Lynx: A genus in the family FELIDAE comprising felines with long legs, ear tufts, and a short tail.. 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol : A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively.. tebuconazole : A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops.		2.0510monochlorobenzenes;
tertiary alcohol;
triazoles
azoxystrobin
azoxystrobin: a methoxyacrylate analog; a strobilurin fungicide; structure given in first source. azoxystrobin : An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.		2.4620aryloxypyrimidine;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
methyl ester;
nitrile		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
quinone outside inhibitor;
xenobiotic
quinoxyfen
quinoxyfen: structure in first source. quinoxyfen : A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.		2.0510aromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines		antifungal agrochemical
kresoxim-methyl
kresoxim-methyl: strobilurin analogue; an industrial fungicide. kresoxim-methyl : A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.		2.4620aromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
pyrachlostrobin
pyraclostrobin : A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres.		2.0810aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalopathy, Toxic
[description not available]		02.4110
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)		07.4110
Abnormalities, Autosome
[description not available]		02.4110
Chromoblastomycosis
Scaly papule or warty growth, caused by five fungi, that spreads as a result of satellite lesions affecting the foot or leg. The extremity may become swollen and, at its distal portion, covered with various nodular, tumorous, verrucous lesions that resemble cauliflower. In rare instances, the disease may begin on the hand or wrist and involve the entire upper extremity. (Arnold, Odom, and James, Andrew's Diseases of the Skin, 8th ed, p362)		02.2510
Diathesis
[description not available]		02.3110
Viral Diseases
[description not available]		02.3110
Virus Diseases
A general term for diseases caused by viruses.		02.3110
Disease Resistance
The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants.		02.3110
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.4420