| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
lamivudine
[no description available] | 2.21 | 1 | 0 | monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol | allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug |
isopimpinellin
isopimpinellin: from Ruta graveolens & Heracleum lanatum; structure | 2.21 | 1 | 0 | psoralens | |
matairesinol
matairesinol: lignan that is a central precursor in plants in the biosynthesis of numerous lignans (coordinate with specific); RN refers to (3R-trans)-isomer. (-)-matairesinol : A lignan that is gamma-butyrolactone in which the 3 and 4 positions are substituted by 4-hydroxy-3-methoxybenzyl groups (the 3R,4R-diastereomer). | 2.1 | 1 | 0 | gamma-lactone;
lignan;
polyphenol | angiogenesis inhibitor;
anti-asthmatic agent;
phytoestrogen;
plant metabolite |
chamaejasmine
chamaejasmine: isolated from Stellera chamaejasmae; structure in first source | 2.21 | 1 | 0 | | |
lariciresinol
lariciresinol: found in human urine. (+)-lariciresinol : A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer). | 2.1 | 1 | 0 | aromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol | antifungal agent;
plant metabolite |
isochamaejasmin
isochamaejasmin: from S. chamaejasme L; structure in first source. isochamaejasmin : A biflavonoid that consists of two units of 5,7,4'-trihydroxyflavanone joined together at position 3 and 3''. | 7.17 | 1 | 0 | biflavonoid;
hydroxyflavone | plant metabolite |
nortrachelogenin
nortrachelogenin: pharmacologically active lignan from Wikstroemia indica; RN & N1 from 9th CI; RN refers to (3S-cis)-isomer; structure in first source | 2.1 | 1 | 0 | lignan | |
lignans
Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) | 2.1 | 1 | 0 | | |
daphnoretin
daphnoretin: isolated from the whole plant Wikstroemia indica. daphnoretin : A member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 6 and a (2-oxo-2H-chromen-7-yl)oxy group at position 3. | 2.54 | 2 | 0 | aromatic ether;
hydroxycoumarin | antineoplastic agent;
antiviral agent;
metabolite |
chamaechromone
chamaechromone: an anti-hepatitis B virus agent isolated from Stellera chamaejasme; structure in first source | 3.06 | 4 | 0 | | |
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 2.54 | 2 | 0 | benzenes;
hydroxycoumarin;
methyl ketone | |