Proteins > Fatty acid-binding protein, liver
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Fatty acid-binding protein, liver
A fatty acid-binding protein, liver that is encoded in the genome of rat. [OMA:P02692, PRO:DNx]
Synonyms
Fatty acid-binding protein 1;
Liver-type fatty acid-binding protein;
L-FABP;
Squalene- and sterol-carrier protein;
SCP;
Z-protein;
p14
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (19)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| aspirin | Rattus norvegicus (Norway rat) | Ki | 2,064.0000 | 2 | 2 |
| atenolol | Rattus norvegicus (Norway rat) | Ki | 717.0000 | 1 | 1 |
| clofibrate | Rattus norvegicus (Norway rat) | Ki | 6.9200 | 1 | 1 |
| diazepam | Rattus norvegicus (Norway rat) | Ki | 57.7655 | 2 | 2 |
| diclofenac | Rattus norvegicus (Norway rat) | Ki | 19.3100 | 2 | 2 |
| fenofibrate | Rattus norvegicus (Norway rat) | Ki | 0.1118 | 3 | 5 |
| flurbiprofen | Rattus norvegicus (Norway rat) | Ki | 111.5900 | 2 | 2 |
| gemfibrozil | Rattus norvegicus (Norway rat) | Ki | 90.4300 | 2 | 2 |
| ibuprofen | Rattus norvegicus (Norway rat) | Ki | 247.8000 | 2 | 2 |
| indoprofen | Rattus norvegicus (Norway rat) | Ki | 81.1350 | 2 | 2 |
| ketorolac | Rattus norvegicus (Norway rat) | Ki | 65.3000 | 2 | 2 |
| lorazepam | Rattus norvegicus (Norway rat) | Ki | 76.4500 | 2 | 2 |
| meclofenamic acid | Rattus norvegicus (Norway rat) | Ki | 0.3175 | 2 | 2 |
| prednisolone | Rattus norvegicus (Norway rat) | Ki | 51.8300 | 2 | 2 |
| phytanic acid | Rattus norvegicus (Norway rat) | Ki | 0.0367 | 1 | 3 |
| bezafibrate | Rattus norvegicus (Norway rat) | Ki | 44.4000 | 1 | 1 |
| sq-11725 | Rattus norvegicus (Norway rat) | Ki | 2,310.0000 | 1 | 1 |
| fenofibric acid | Rattus norvegicus (Norway rat) | Ki | 6.8388 | 3 | 5 |
| oleic acid | Rattus norvegicus (Norway rat) | Ki | 1.5400 | 2 | 2 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| clofibrate | Rattus norvegicus (Norway rat) | Kd | 8.6625 | 8 | 8 |
| fenofibrate | Rattus norvegicus (Norway rat) | Kd | 0.1378 | 15 | 15 |
| fenofibric acid | Rattus norvegicus (Norway rat) | Kd | 12.6463 | 15 | 15 |
Probing the fibrate binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Sep-10, Volume: 52, Issue:17, 2009
Characterization of the drug binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Jul-10, Volume: 51, Issue:13, 2008
The human liver fatty acid binding protein T94A variant alters the structure, stability, and interaction with fibrates.Biochemistry, , Dec-23, Volume: 52, Issue:51, 2013
Probing the fibrate binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Sep-10, Volume: 52, Issue:17, 2009
Characterization of the drug binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Jul-10, Volume: 51, Issue:13, 2008
The human liver fatty acid binding protein T94A variant alters the structure, stability, and interaction with fibrates.Biochemistry, , Dec-23, Volume: 52, Issue:51, 2013
Probing the fibrate binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Sep-10, Volume: 52, Issue:17, 2009
Characterization of the drug binding specificity of rat liver fatty acid binding protein.Journal of medicinal chemistry, , Jul-10, Volume: 51, Issue:13, 2008