Page last updated: 2024-10-16

carnitine and Sensitivity and Specificity

carnitine has been researched along with Sensitivity and Specificity in 71 studies

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"To determine the sensitivity and specificity of detecting urinary medium-chain acylcarnitines for the diagnosis of MCAD deficiency, 114 urine specimens from 75 children with metabolic diseases and controls were analyzed in a blinded fashion using a radioisotopic exchange/HPLC method."7.68Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method. ( Gage, DA; Huang, ZH; Kossak, D; Li, BU; Penn, D; Rinaldo, P; Schmidt-Sommerfeld, E, 1992)
"l-Carnitine levels were increased in HF patients, but decreased according to the severity of cardiac decompensation."5.33Inflammation and perturbation of the l-carnitine system in heart failure. ( Dalla Libera, L; Gobbo, V; Ravara, B; Vescovo, G, 2005)
"Urinary organic acids, plasma amino acids and acylcarnitine profile analyses are the main tools used to diagnose inborn errors of metabolisms (IEMs)."3.78Quantification of acylglycines in human urine by HPLC electrospray ionization-tandem mass spectrometry and the establishment of pediatric reference interval in local Chinese. ( Fong, BM; Leung, KS; Tam, S, 2012)
" We investigated whether sodium bicarbonate-induced metabolic alkalosis could positively affect force development during the rest-to-work transition in ischaemic skeletal muscle."3.71Bicarbonate-induced alkalosis augments cellular acetyl group availability and isometric force during the rest-to-work transition in canine skeletal muscle. ( Constantin-Teodosiu, D; Greenhaff, PL; Loxham, SJ; Poucher, SM; Roberts, PA, 2002)
"To determine the sensitivity and specificity of detecting urinary medium-chain acylcarnitines for the diagnosis of MCAD deficiency, 114 urine specimens from 75 children with metabolic diseases and controls were analyzed in a blinded fashion using a radioisotopic exchange/HPLC method."3.68Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method. ( Gage, DA; Huang, ZH; Kossak, D; Li, BU; Penn, D; Rinaldo, P; Schmidt-Sommerfeld, E, 1992)
"Correct staging of hepatocellular carcinoma (HCC) could help physicians to precisely select treatments for patients, such as surgery, chemotherapy, or their combination."1.48Dysregulated serum metabolites in staging of hepatocellular carcinoma. ( Chen, N; Chen, Y; Lou, B; Lv, J; Mao, W; Wang, P; Wang, W, 2018)
"Current screening methods for gestational diabetes mellitus (GDM) are insufficient in detecting the risk of GDM in the first trimester of the pregnancy."1.43First-Trimester Maternal Serum Amino Acids and Acylcarnitines Are Significant Predictors of Gestational Diabetes. ( Appelblom, H; Gissler, M; Nevalainen, J; Ryynänen, M; Sairanen, M; Timonen, S, 2016)
"Increasing evidence suggest that Alzheimer's disease (AD) is a heterogeneous disorder that includes several subtypes with different etiology and progression."1.40Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease. ( Cedazo-Mínguez, Á; Cifuentes, A; Ibáñez, C; Lodeiro, M; Simó, C, 2014)
"Betaines were derivatized with butanol previous to their baseline separation in 10 min using a 0."1.37Determination of betaines in vegetable oils by capillary electrophoresis tandem mass spectrometry--application to the detection of olive oil adulteration with seed oils. ( Castro-Puyana, M; Crego, AL; Luisa Marina, M; Sánchez-Hernández, L, 2011)
"L-carnitine is a naturally occurring quaternary ammonium compound present in all mammalian species."1.33Determination of total and free plasma carnitine concentrations on the Dade Behring Dimension RxL: integrated chemistry system. ( Ghoshal, AK; Soldin, SJ, 2005)
"Sensitivity and specificity were evaluated by identifying patient samples under a wide variety of clinical conditions."1.33Rapid measurement of plasma acylcarnitines by liquid chromatography-tandem mass spectrometry without derivatization. ( Ghoshal, AK; Guo, T; Soldin, SJ; Soukhova, N, 2005)
"l-Carnitine levels were increased in HF patients, but decreased according to the severity of cardiac decompensation."1.33Inflammation and perturbation of the l-carnitine system in heart failure. ( Dalla Libera, L; Gobbo, V; Ravara, B; Vescovo, G, 2005)
"In 106 newborns, confirmed inborn errors of metabolism were found."1.32Expanded newborn screening for inborn errors of metabolism by electrospray ionization-tandem mass spectrometry: results, outcome, and implications. ( Hoffmann, GF; Kohlmüller, D; Lindner, M; Mayatepek, E; Olgemöller, K; Schulze, A, 2003)
"Acylcarnitines were analyzed using tandem mass spectrometry."1.32A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. ( Bali, D; Gregersen, N; Koeberl, DD; Liu, HM; Matern, D; Millington, DS; Stevens, RD; Young, SP, 2003)
" We used this special combination to develop an easy and convenient procedure for the enantio- and chemo-selective dosage of propionyl L-carnitine (1) and relative impurities (2-6), which allowed for the simultaneous separation and quantitation within 30 min."1.32Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities. ( Badaloni, E; D'Acquarica, I; Galletti, B; Gasparrini, F; Giannoli, B; Giorgi, F; Tinti, MO; Vigevani, A, 2004)
" There was negative linear correlation between the dosage of carnitine and formation of [(3)H]AFB(1)-DNA adducts in the hepatocytes; however, the partitioning of AFB(1) into cellular compartments was not affected by carnitine."1.31Carnitine alters binding of aflatoxin to DNA and proteins in rat hepatocytes and cell-free systems. ( Sachan, DS; Yatim, AM, 2001)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (23.94)18.2507
2000's30 (42.25)29.6817
2010's23 (32.39)24.3611
2020's1 (1.41)2.80

Authors

AuthorsStudies
Lu, J1
Guo, Y1
Lu, Y1
Ji, W1
Lin, L1
Qian, W1
Chen, W1
Wang, J2
Lv, X1
Ke, M1
Kong, D1
Shen, Q1
Zhu, Y1
Liu, P1
Su, J1
Wang, L1
Li, Y1
Gao, P1
Shan, J1
Liu, S1
Huffnagel, IC1
van de Beek, MC1
Showers, AL1
Orsini, JJ1
Klouwer, FCC1
Dijkstra, IME1
Schielen, PC1
van Lenthe, H1
Wanders, RJA1
Vaz, FM2
Morrissey, MA2
Engelen, M1
Kemp, S1
Céspedes, N1
Valencia, A1
Echeverry, CA1
Arce-Plata, MI1
Colón, C1
Castiñeiras, DE1
Hurtado, PM1
Cocho, JA1
Herrera, S1
Arévalo-Herrera, M1
Wang, W1
Lv, J1
Chen, N1
Lou, B1
Mao, W1
Wang, P1
Chen, Y1
Magiera, S1
Baranowska, I1
Kusa, J1
Baranowski, J1
Uzunoglu, S1
Cosar, R1
Cicin, I1
Ibis, K1
Demiralay, E1
Benlier, E1
Erdogan, B1
Kandulu, H1
Ozen, A1
Altaner, S1
Peng, M1
Liu, L1
Jiang, M1
Liang, C1
Zhao, X2
Cai, Y1
Sheng, H1
Ou, Z1
Luo, H1
Golbahar, J1
Altayab, DD1
Carreon, E1
Lodeiro, M1
Ibáñez, C1
Cifuentes, A1
Simó, C1
Cedazo-Mínguez, Á1
Mapstone, M1
Cheema, AK1
Fiandaca, MS1
Zhong, X1
Mhyre, TR1
MacArthur, LH1
Hall, WJ1
Fisher, SG1
Peterson, DR1
Haley, JM1
Nazar, MD1
Rich, SA1
Berlau, DJ1
Peltz, CB1
Tan, MT1
Kawas, CH1
Federoff, HJ1
Nobuoka, Y1
Ogawa, R1
Echizen, H1
Liu, X1
Zheng, P1
Zhang, Y1
Hu, C1
Li, J1
Zhao, J1
Zhou, J1
Xie, P1
Xu, G1
Gong, Z1
Xu, WJ1
Tian, GL1
Zhang, T1
Lv, Z1
Minkler, PE4
Stoll, MS1
Ingalls, ST3
Kerner, J2
Hoppel, CL4
Chen, YX1
Zhang, XJ1
Huang, J1
Zhou, SJ1
Liu, F1
Jiang, LL1
Chen, M1
Wan, JB1
Yang, DZ1
Lin, Y1
Lin, W1
Yu, K1
Zheng, F1
Zheng, Z1
Fu, Q1
Stoll, MSK1
Nevalainen, J1
Sairanen, M1
Appelblom, H1
Gissler, M1
Timonen, S1
Ryynänen, M1
Liu, Z1
Mutlib, AE1
Talaat, RE1
Chalcraft, KR1
Britz-McKibbin, P1
Castro-Puyana, M2
García-Ruiz, C2
Crego, AL3
Marina, ML2
Sánchez-Hernández, L2
McHugh, D1
Cameron, CA1
Abdenur, JE1
Abdulrahman, M1
Adair, O1
Al Nuaimi, SA1
Åhlman, H1
Allen, JJ1
Antonozzi, I1
Archer, S1
Au, S1
Auray-Blais, C1
Baker, M1
Bamforth, F1
Beckmann, K1
Pino, GB1
Berberich, SL1
Binard, R1
Boemer, F1
Bonham, J1
Breen, NN1
Bryant, SC2
Caggana, M2
Caldwell, SG2
Camilot, M2
Campbell, C2
Carducci, C2
Cariappa, R1
Carlisle, C1
Caruso, U1
Cassanello, M1
Castilla, AM1
Ramos, DE1
Chakraborty, P1
Chandrasekar, R1
Ramos, AC1
Cheillan, D1
Chien, YH1
Childs, TA1
Chrastina, P1
Sica, YC1
de Juan, JA1
Colandre, ME1
Espinoza, VC1
Corso, G1
Currier, R1
Cyr, D1
Czuczy, N1
D'Apolito, O1
Davis, T1
de Sain-Van der Velden, MG1
Delgado Pecellin, C1
Di Gangi, IM1
Di Stefano, CM1
Dotsikas, Y1
Downing, M1
Downs, SM1
Dy, B1
Dymerski, M1
Rueda, I1
Elvers, B1
Eaton, R1
Eckerd, BM1
El Mougy, F1
Eroh, S1
Espada, M1
Evans, C1
Fawbush, S1
Fijolek, KF1
Fisher, L1
Franzson, L1
Frazier, DM1
Garcia, LR1
Bermejo, MS1
Gavrilov, D1
Gerace, R1
Giordano, G1
Irazabal, YG1
Greed, LC1
Grier, R1
Grycki, E1
Gu, X1
Gulamali-Majid, F1
Hagar, AF1
Han, L1
Hannon, WH1
Haslip, C1
Hassan, FA1
He, M1
Hietala, A1
Himstedt, L1
Hoffman, GL1
Hoffman, W1
Hoggatt, P1
Hopkins, PV1
Hougaard, DM1
Hughes, K1
Hunt, PR1
Hwu, WL1
Hynes, J1
Ibarra-González, I1
Ingham, CA1
Ivanova, M1
Jacox, WB1
John, C1
Johnson, JP1
Jónsson, JJ1
Karg, E1
Kasper, D1
Klopper, B1
Katakouzinos, D1
Khneisser, I1
Knoll, D1
Kobayashi, H1
Koneski, R1
Kozich, V1
Kouapei, R1
Kohlmueller, D1
Kremensky, I1
la Marca, G1
Lavochkin, M1
Lee, SY1
Lehotay, DC1
Lemes, A1
Lepage, J1
Lesko, B1
Lewis, B1
Lim, C1
Linard, S1
Lindner, M3
Lloyd-Puryear, MA1
Lorey, F1
Loukas, YL1
Luedtke, J1
Maffitt, N1
Magee, JF1
Manning, A1
Manos, S1
Marie, S1
Hadachi, SM1
Marquardt, G1
Martin, SJ1
Matern, D3
Mayfield Gibson, SK1
Mayne, P1
McCallister, TD1
McCann, M1
McClure, J1
McGill, JJ1
McKeever, CD1
McNeilly, B1
Moutsatsou, P1
Mulcahy, EA1
Nikoloudis, D1
Norgaard-Pedersen, B1
Oglesbee, D1
Oltarzewski, M1
Ombrone, D1
Ojodu, J1
Papakonstantinou, V1
Reoyo, SP1
Park, HD1
Pasquali, M1
Pasquini, E1
Patel, P1
Pass, KA1
Peterson, C1
Pettersen, RD1
Pitt, JJ2
Poh, S1
Pollak, A1
Porter, C1
Poston, PA2
Price, RW1
Queijo, C1
Quesada, J1
Randell, E1
Ranieri, E1
Raymond, K1
Reddic, JE1
Reuben, A1
Ricciardi, C1
Rinaldo, P2
Rivera, JD1
Roberts, A1
Rocha, H1
Roche, G1
Greenberg, CR1
Mellado, JM1
Juan-Fita, MJ1
Ruiz, C1
Ruoppolo, M1
Rutledge, SL1
Ryu, E1
Saban, C1
Sahai, I1
García-Blanco, MI1
Santiago-Borrero, P1
Schenone, A1
Schoos, R1
Schweitzer, B1
Scott, P1
Seashore, MR1
Seeterlin, MA1
Sesser, DE1
Sevier, DW1
Shone, SM1
Sinclair, G1
Skrinska, VA1
Stanley, EL1
Strovel, ET1
Jones, AL1
Sunny, S1
Takats, Z1
Tanyalcin, T1
Teofoli, F1
Thompson, JR1
Tomashitis, K1
Domingos, MT1
Torres, J1
Torres, R1
Tortorelli, S1
Turi, S1
Turner, K1
Tzanakos, N1
Valiente, AG1
Vallance, H1
Vela-Amieva, M1
Vilarinho, L1
von Döbeln, U1
Vincent, MF1
Vorster, BC1
Watson, MS1
Webster, D1
Weiss, S1
Wilcken, B2
Wiley, V3
Williams, SK1
Willis, SA1
Woontner, M1
Wright, K1
Yahyaoui, R1
Yamaguchi, S2
Yssel, M1
Zakowicz, WM1
Pormsila, W1
Morand, R1
Krähenbühl, S2
Hauser, PC1
Luisa Marina, M1
Fong, BM1
Tam, S1
Leung, KS1
Miller, JH1
Karnes, HT1
Di Tullio, A1
D'Acquarica, I2
Gasparrini, F2
Desiderio, P1
Giannessi, F1
Muck, S1
Piccirilli, F1
Tinti, MO2
Villani, C1
Okun, JG1
Kölker, S1
Schulze, A3
Kohlmüller, D2
Olgemöller, K2
Hoffmann, GF2
Wanders, RJ3
Mayatepek, E2
Roberts, PA1
Loxham, SJ1
Poucher, SM1
Constantin-Teodosiu, D1
Greenhaff, PL1
Alvarez-Vasquez, F1
Cánovas, M2
Iborra, JL3
Torres, NV1
Mueller, P1
Schindler, I1
Ethofer, T1
Buehrdel, P1
Ceglarek, U1
Young, SP1
Gregersen, N1
Stevens, RD1
Bali, D1
Liu, HM1
Koeberl, DD1
Millington, DS2
McEntyre, CJ1
Lever, M2
Storer, MK1
Vernez, L1
Wenk, M1
Napolitano, N1
Giannoli, B1
Badaloni, E1
Galletti, B1
Giorgi, F1
Vigevani, A1
North, KN1
Hasegawa, Y1
Iga, M1
Kimura, M1
Shigematsu, Y1
Ghoshal, AK2
Soldin, SJ2
Guo, T1
Soukhova, N1
Vescovo, G1
Ravara, B1
Gobbo, V1
Dalla Libera, L1
Holub, M1
Tuschl, K1
Ratschmann, R1
Strnadová, KA1
Mühl, A1
Heinze, G1
Sperl, W1
Bodamer, OA1
Cibulka, R1
Siroka, R1
Trefil, L1
Racek, J1
Vesela, E1
Prieto, JA1
Andrade, F1
Aldámiz-Echevarría, L1
Sanjurjo, P1
Pollitt, RJ1
Matthews, AJ1
Muro, H1
Tatsuhara, T1
Sugimoto, T1
Woo, M1
Nishida, N1
Murakami, K1
Yamaguchi, Y1
Kamimori, H1
Hamashima, Y1
Konishi, M2
Takahashi, M1
Ueda, S1
Misaki, H1
Sugiyama, N1
Matsumoto, K1
Matsuo, N1
Murao, S1
Brass, EP1
Hiatt, WR1
Longo, A1
Bruno, G1
Curti, S1
Mancinelli, A1
Miotto, G1
Costa, CG1
Struys, EA1
Bootsma, A2
ten Brink, HJ1
Dorland, L1
Tavares de Almeida, I1
Duran, M1
Jakobs, C1
Delolme, F1
Vianey-Saban, C1
Guffon, N1
Favre-Bonvin, J1
Guibaud, P1
Becchi, M1
Mathieu, M1
Divry, P1
Wan, L1
Hubbard, RW1
Johnson, WA1
Landry, GL1
Terada, N1
Inoue, F1
Okochi, M1
Nakajima, H1
Kizaki, Z1
Kinugasa, A1
Sawada, T1
Obón, JM2
Buendía, B1
Carpenter, K1
Heinig, K1
Henion, J1
Vreken, P2
van Lint, AE1
Bootsma, AH1
Overmars, H1
van Gennip, AH2
Manjón, A1
Van Hove, JL1
Kahler, SG1
Feezor, MD1
Ramakrishna, JP1
Hart, P1
Treem, WR1
Shen, JJ1
Yatim, AM1
Sachan, DS1
Braida, L1
Crovella, S1
Boniotto, M1
Luchesi, A1
de Vonderweid, U1
Casetta, B1
Amoroso, A1
Fingerhut, R1
Röschinger, W1
Muntau, AC1
Dame, T1
Kreischer, J1
Arnecke, R1
Superti-Furga, A1
Troxler, H1
Liebl, B1
Olgemöller, B1
Roscher, AA1
Durán, JM1
Peral, MJ1
Calonge, ML1
Ilundáin, AA1
Melegh, B1
Bene, J1
Cuebas, D1
Gage, DA2
Bieber, LL1
Hashimoto, H1
Bason, L1
Leaver, C1
Hayman, CM1
Chambers, ST1
Schmidt-Sommerfeld, E1
Penn, D1
Kossak, D1
Li, BU1
Huang, ZH1

Reviews

1 review available for carnitine and Sensitivity and Specificity

ArticleYear
Nutritional supplements: fact vs. fiction.
    Adolescent medicine (Philadelphia, Pa.), 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Amino Acids; Carnitine; Creatine; Dietar

1998

Other Studies

70 other studies available for carnitine and Sensitivity and Specificity

ArticleYear
Untargeted lipidomics reveals specific lipid abnormalities in Sjögren's syndrome.
    Rheumatology (Oxford, England), 2021, 03-02, Volume: 60, Issue:3

    Topics: Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Discriminant Anal

2021
Comparison of C26:0-carnitine and C26:0-lysophosphatidylcholine as diagnostic markers in dried blood spots from newborns and patients with adrenoleukodystrophy.
    Molecular genetics and metabolism, 2017, Volume: 122, Issue:4

    Topics: Adrenoleukodystrophy; Adult; ATP Binding Cassette Transporter, Subfamily D, Member 1; Biomarkers; Ca

2017
Reference values of amino acids, acylcarnitines and succinylacetone by tandem mass spectrometry for use in newborn screening in southwest Colombia.
    Colombia medica (Cali, Colombia), 2017, Sep-30, Volume: 48, Issue:3

    Topics: Amino Acids; Biomarkers; Carnitine; Colombia; Cross-Sectional Studies; False Positive Reactions; Hep

2017
Dysregulated serum metabolites in staging of hepatocellular carcinoma.
    Clinical biochemistry, 2018, Volume: 61

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Carnitine; China; Cohort Studies; Docosah

2018
A liquid chromatography and tandem mass spectrometry method for the determination of potential biomarkers of cardiovascular disease.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Mar-01, Volume: 919-920

    Topics: Acetylcarnitine; Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid;

2013
Carnitine or dimethyl sulfoxide, or both, for the treatment of anthracycline extravasation in rats.
    Journal of plastic surgery and hand surgery, 2013, Volume: 47, Issue:5

    Topics: Administration, Topical; Animals; Anthracyclines; Carnitine; Dimethyl Sulfoxide; Disease Models, Ani

2013
Measurement of free carnitine and acylcarnitines in plasma by HILIC-ESI-MS/MS without derivatization.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Aug-01, Volume: 932

    Topics: Carnitine; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Isomerism; Sens

2013
Short-term stability of amino acids and acylcarnitines in the dried blood spots used to screen newborns for metabolic disorders.
    Journal of medical screening, 2014, Volume: 21, Issue:1

    Topics: Amino Acids; Blood Specimen Collection; Carnitine; Dried Blood Spot Testing; Humans; Infant, Newborn

2014
Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 41, Issue:1

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Arginine; Biomarkers; Carnitine;

2014
Plasma phospholipids identify antecedent memory impairment in older adults.
    Nature medicine, 2014, Volume: 20, Issue:4

    Topics: Aged; Alzheimer Disease; Asparagine; Biomarkers; Carnitine; Cognitive Dysfunction; Cohort Studies; D

2014
Simultaneous determination of N(1)-methylnicotinamide, L-carnitine, and creatinine in human plasma and urine by liquid chromatography with mass spectrometry for assessing the activities of multiple renal cationic transporters.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Sep-15, Volume: 967

    Topics: Carnitine; Chromatography, Liquid; Creatinine; Drug Stability; Female; Humans; Male; Mass Spectromet

2014
Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography-mass spectrometry.
    Journal of proteome research, 2015, May-01, Volume: 14, Issue:5

    Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, Liquid; Depressive Disorder, Maj

2015
Neonatal Intrahepatic Cholestasis Caused by Citrin Deficiency Differentiated from Biliary Atresia.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2016, Volume: 26, Issue:3

    Topics: Amino Acids; Analysis of Variance; Biliary Atresia; Bilirubin; Calcium-Binding Proteins; Carnitine;

2016
Quantitative acylcarnitine determination by UHPLC-MS/MS--Going beyond tandem MS acylcarnitine "profiles".
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Acetyl-CoA C-Acyltransferase; Acyl-CoA Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Betaine;

2015
UHPLC/Q-TOFMS-based plasma metabolomics of polycystic ovary syndrome patients with and without insulin resistance.
    Journal of pharmaceutical and biomedical analysis, 2016, Mar-20, Volume: 121

    Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Fatty Acid

2016
[Mutational analysis of SLC22A5 gene in eight patients with systemic primary carnitine deficiency].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2017, Feb-10, Volume: 34, Issue:1

    Topics: Adult; Amino Acid Sequence; Base Sequence; Cardiomyopathies; Carnitine; DNA Mutational Analysis; Fem

2017
Correcting false positive medium-chain acyl-CoA dehydrogenase deficiency results from newborn screening; synthesis, purification, and standardization of branched-chain C8 acylcarnitines for use in their selective and accurate absolute quantitation by UHPL
    Molecular genetics and metabolism, 2017, Volume: 120, Issue:4

    Topics: Acyl-CoA Dehydrogenase; Carnitine; Chromatography, High Pressure Liquid; False Positive Reactions; H

2017
First-Trimester Maternal Serum Amino Acids and Acylcarnitines Are Significant Predictors of Gestational Diabetes.
    The review of diabetic studies : RDS, 2016,Winter, Volume: 13, Issue:4

    Topics: Adult; Arginine; Biomarkers; Carnitine; Case-Control Studies; Diabetes, Gestational; Down-Regulation

2016
Liquid chromatography/mass spectrometry determination of endogenous plasma acetyl and palmitoyl carnitines as potential biomarkers of beta-oxidation in mice.
    Rapid communications in mass spectrometry : RCM, 2008, Volume: 22, Issue:21

    Topics: Animals; Biomarkers; Calibration; Carnitine; Chromatography, Liquid; Isotope Labeling; Male; Mass Sp

2008
Newborn screening of inborn errors of metabolism by capillary electrophoresis-electrospray ionization-mass spectrometry: a second-tier method with improved specificity and sensitivity.
    Analytical chemistry, 2009, Jan-01, Volume: 81, Issue:1

    Topics: Adult; Amino Acids; Calibration; Carnitine; Electrophoresis, Capillary; Humans; Infant, Newborn; Mas

2009
Development of a CE-MS(2) method for the enantiomeric separation of L/D-carnitine: application to the analysis of infant formulas.
    Electrophoresis, 2009, Volume: 30, Issue:2

    Topics: Carnitine; Electrophoresis, Capillary; Humans; Infant Formula; Sensitivity and Specificity; Spectrom

2009
Sensitive determination of D-carnitine as enantiomeric impurity of levo-carnitine in pharmaceutical formulations by capillary electrophoresis-tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2010, Dec-15, Volume: 53, Issue:5

    Topics: Carnitine; Chemistry, Pharmaceutical; Drug Contamination; Electrophoresis, Capillary; Sensitivity an

2010
Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2011, Volume: 13, Issue:3

    Topics: Amino Acids; Carnitine; Humans; Infant, Newborn; International Cooperation; Metabolic Diseases; Neon

2011
Capillary electrophoresis with contactless conductivity detection for the determination of carnitine and acylcarnitines in clinical samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Apr-15, Volume: 879, Issue:13-14

    Topics: Carnitine; Electric Conductivity; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Li

2011
Determination of betaines in vegetable oils by capillary electrophoresis tandem mass spectrometry--application to the detection of olive oil adulteration with seed oils.
    Electrophoresis, 2011, Volume: 32, Issue:11

    Topics: Alkaloids; Betaine; Carnitine; Electrophoresis, Capillary; Linear Models; Olive Oil; Plant Oils; Pro

2011
Quantification of acylglycines in human urine by HPLC electrospray ionization-tandem mass spectrometry and the establishment of pediatric reference interval in local Chinese.
    Talanta, 2012, Jan-15, Volume: 88

    Topics: 1-Butanol; Acylation; Adolescent; Asian People; Calibration; Carnitine; Child; Child, Preschool; Chr

2012
A quantitative method for acylcarnitines and amino acids using high resolution chromatography and tandem mass spectrometry in newborn screening dried blood spot analysis.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Aug-15, Volume: 903

    Topics: Amino Acids; Carnitine; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Humans; Infa

2012
The first gas chromatographic resolution of carnitine enantiomers.
    Chemical communications (Cambridge, England), 2002, Mar-07, Issue:5

    Topics: 4-Butyrolactone; Carnitine; Chromatography, Gas; Cyclodextrins; Sensitivity and Specificity; Stereoi

2002
A method for quantitative acylcarnitine profiling in human skin fibroblasts using unlabelled palmitic acid: diagnosis of fatty acid oxidation disorders and differentiation between biochemical phenotypes of MCAD deficiency.
    Biochimica et biophysica acta, 2002, Oct-10, Volume: 1584, Issue:2-3

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Carnitine; Cells, Cultured; Fibroblasts; Humans; In

2002
Bicarbonate-induced alkalosis augments cellular acetyl group availability and isometric force during the rest-to-work transition in canine skeletal muscle.
    Experimental physiology, 2002, Volume: 87, Issue:4

    Topics: Acetylcarnitine; Alkalosis; Animals; Carnitine; Dogs; Electric Stimulation; Female; Infusions, Intra

2002
Modeling, optimization and experimental assessment of continuous L-(-)-carnitine production by Escherichia coli cultures.
    Biotechnology and bioengineering, 2002, Dec-30, Volume: 80, Issue:7

    Topics: Alcohol Oxidoreductases; Algorithms; Bioreactors; Carnitine; Computer Simulation; Escherichia coli;

2002
Validation of an ESI-MS/MS screening method for acylcarnitine profiling in urine specimens of neonates, children, adolescents and adults.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 327, Issue:1-2

    Topics: Adolescent; Adult; Age Factors; Carnitine; Case-Control Studies; Child; Child, Preschool; Humans; In

2003
Expanded newborn screening for inborn errors of metabolism by electrospray ionization-tandem mass spectrometry: results, outcome, and implications.
    Pediatrics, 2003, Volume: 111, Issue:6 Pt 1

    Topics: Acyl-CoA Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carnitine; Cohort Studies

2003
A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 337, Issue:1-2

    Topics: Acyl-CoA Dehydrogenase; Butyric Acid; Butyryl-CoA Dehydrogenase; Carbon Isotopes; Carnitine; Deuteri

2003
A high performance liquid chromatographic method for the measurement of total carnitine in human plasma and urine.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 344, Issue:1-2

    Topics: Carnitine; Chromatography, High Pressure Liquid; Diagnostic Techniques and Procedures; Humans; Refer

2004
Determination of carnitine and acylcarnitines in plasma by high-performance liquid chromatography/electrospray ionization ion trap tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:11

    Topics: Calibration; Carnitine; Chromatography, High Pressure Liquid; Humans; Methylmalonic Acid; Reference

2004
Pseudo-glutarylcarnitinaemia in medium-chain acyl-CoA dehydrogenase deficiency detected by tandem mass spectrometry newborn screening.
    Journal of inherited metabolic disease, 2004, Volume: 27, Issue:4

    Topics: Acetylation; Acyl-CoA Dehydrogenase; Carnitine; False Positive Reactions; Fatty Acids; Gas Chromatog

2004
Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities.
    Journal of chromatography. A, 2004, Dec-24, Volume: 1061, Issue:2

    Topics: Carnitine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Reproducibility of Resu

2004
Quantitation of long-chain acylcarnitines by HPLC/fluorescence detection: application to plasma and tissue specimens from patients with carnitine palmitoyltransferase-II deficiency.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 352, Issue:1-2

    Topics: Carnitine; Carnitine O-Palmitoyltransferase; Chromatography, High Pressure Liquid; Humans; Lipid Met

2005
Prenatal diagnosis for organic acid disorders using two mass spectrometric methods, gas chromatography mass spectrometry and tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Aug-25, Volume: 823, Issue:1

    Topics: Amniotic Fluid; Carboxylic Acids; Carnitine; Female; Fetal Diseases; Gas Chromatography-Mass Spectro

2005
Determination of total and free plasma carnitine concentrations on the Dade Behring Dimension RxL: integrated chemistry system.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 361, Issue:1-2

    Topics: Carnitine; Humans; Sensitivity and Specificity

2005
Rapid measurement of plasma acylcarnitines by liquid chromatography-tandem mass spectrometry without derivatization.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 358, Issue:1-2

    Topics: Acylation; Carnitine; Chromatography, Liquid; Mass Spectrometry; Sensitivity and Specificity; Time F

2005
Inflammation and perturbation of the l-carnitine system in heart failure.
    European journal of heart failure, 2005, Volume: 7, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carnitine; Case-Control Studies; Enzyme-Linked Immunosorbent Assay;

2005
Influence of hematocrit and localisation of punch in dried blood spots on levels of amino acids and acylcarnitines measured by tandem mass spectrometry.
    Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 373, Issue:1-2

    Topics: Amino Acids; Blood Specimen Collection; Blood Stains; Carnitine; Glycine; Hematocrit; Humans; Sensit

2006
Measurement of carnitine in hemodialysis patients - adaptation of an enzymatic photometric method for an automatic analyzer.
    Clinical chemistry and laboratory medicine, 2006, Volume: 44, Issue:8

    Topics: Adult; Aged; Automation; Carnitine; Clinical Enzyme Tests; Female; Humans; Male; Middle Aged; Photom

2006
Determination of free and total carnitine in plasma by an enzymatic reaction and spectrophotometric quantitation spectrophotometric determination of carnitine.
    Clinical biochemistry, 2006, Volume: 39, Issue:10

    Topics: Calibration; Carnitine; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Spe

2006
Population quantile-quantile plots for monitoring assay performance in newborn screening.
    Journal of inherited metabolic disease, 2007, Volume: 30, Issue:4

    Topics: Calibration; Carnitine; DNA Mutational Analysis; Humans; Infant, Newborn; Mass Screening; Mass Spect

2007
Determination of urinary valproylcarnitine by gas chromatography-mass spectrometry with selected-ion monitoring.
    Journal of chromatography. B, Biomedical applications, 1995, Jan-06, Volume: 663, Issue:1

    Topics: Calibration; Carbon Tetrachloride; Carnitine; Dimethylformamide; Drug Stability; Epilepsy; Gas Chrom

1995
Determination of carnitine and saturated-acyl group carnitines in human urine by high-performance liquid chromatography with fluorescence detection.
    Analytical biochemistry, 1994, May-01, Volume: 218, Issue:2

    Topics: Acetylation; Acetylcarnitine; Calibration; Carnitine; Chromatography, High Pressure Liquid; Chromato

1994
Carnitine determination by an enzymatic cycling method with carnitine dehydrogenase.
    Clinical chemistry, 1994, Volume: 40, Issue:5

    Topics: Alcaligenes; Alcohol Oxidoreductases; Carnitine; Female; Humans; Hydrogen-Ion Concentration; Male; N

1994
Quantification of carnitine, acetylcarnitine, and total carnitine in tissues by high-performance liquid chromatography: the effect of exercise on carnitine homeostasis in man.
    Analytical biochemistry, 1995, Nov-01, Volume: 231, Issue:2

    Topics: Acetophenones; Acetylcarnitine; Carnitine; Chromatography, High Pressure Liquid; Exercise; Homeostas

1995
Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene.
    Journal of chromatography. B, Biomedical applications, 1996, Nov-15, Volume: 686, Issue:2

    Topics: Acetylcarnitine; Anthracenes; Carnitine; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hum

1996
Quantitative analysis of plasma acylcarnitines using gas chromatography chemical ionization mass fragmentography.
    Journal of lipid research, 1997, Volume: 38, Issue:1

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Acylation; Carnitine; Case-Control Studi

1997
[Study of plasma acylcarnitines using tandem mass spectrometry. Application to the diagnosis of metabolism hereditary diseases].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1997, Volume: 4, Issue:9

    Topics: Acyl Coenzyme A; Acylation; Amniotic Fluid; Carnitine; Child; Fatty Acids; Female; Humans; Metabolis

1997
Determination of free and total carnitine with a random-access chemistry analyzer.
    Clinical chemistry, 1998, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Autoanalysis; Blood Proteins; Carnitine; Child; Child, Preschool; Humans; Infant;

1998
Measurement of carnitine precursors, epsilon-trimethyllysine and gamma-butyrobetaine in human serum by tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Aug-06, Volume: 731, Issue:1

    Topics: Betaine; Carnitine; Humans; Lysine; Mass Spectrometry; Methylation; Reference Standards; Sensitivity

1999
Enzymatic cycling assay for D-carnitine determination.
    Analytical biochemistry, 1999, Oct-01, Volume: 274, Issue:1

    Topics: Alcohol Oxidoreductases; Automation; Biotransformation; Carnitine; Carnitine O-Acetyltransferase; Es

1999
Newborn screening with tandem mass spectrometry: 12 months' experience in NSW Australia.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1999, Volume: 88, Issue:432

    Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Humans; Infant, Newborn; Male; Mass Spectro

1999
Determination of carnitine and acylcarnitines in biological samples by capillary electrophoresis-mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-10, Volume: 735, Issue:2

    Topics: Carnitine; Electrophoresis, Capillary; Humans; Mass Spectrometry; Reproducibility of Results; Sensit

1999
Rapid diagnosis of organic acidemias and fatty-acid oxidation defects by quantitative electrospray tandem-MS acyl-carnitine analysis in plasma.
    Advances in experimental medicine and biology, 1999, Volume: 466

    Topics: Acyl-CoA Dehydrogenases; Biomarkers; Calibration; Carnitine; Carnitine O-Palmitoyltransferase; Human

1999
Determination of L-carnitine by flow injection analysis with NADH fluorescence detection.
    Analytical biochemistry, 2000, Jun-01, Volume: 281, Issue:2

    Topics: Alcohol Oxidoreductases; Calibration; Carnitine; Enzymes, Immobilized; Flow Injection Analysis; NAD;

2000
Acylcarnitines in plasma and blood spots of patients with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase defiency.
    Journal of inherited metabolic disease, 2000, Volume: 23, Issue:6

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Carnitine; Erythrocytes; False Negative Reactions; Female; Genotyp

2000
Carnitine alters binding of aflatoxin to DNA and proteins in rat hepatocytes and cell-free systems.
    The Journal of nutrition, 2001, Volume: 131, Issue:7

    Topics: Aflatoxin B1; Animals; Biomarkers; Carnitine; Cells, Cultured; Choline; DNA Adducts; Dose-Response R

2001
A rapid and quantitative mass spectrometry method for determining the concentration of acylcarnitines and aminoacids in amniotic fluid.
    Prenatal diagnosis, 2001, Volume: 21, Issue:7

    Topics: Amino Acids; Amniotic Fluid; Carnitine; Female; Fetal Diseases; Humans; Mass Spectrometry; Metabolic

2001
Hepatic carnitine palmitoyltransferase I deficiency: acylcarnitine profiles in blood spots are highly specific.
    Clinical chemistry, 2001, Volume: 47, Issue:10

    Topics: Biomarkers; Blood Specimen Collection; Carnitine; Carnitine O-Palmitoyltransferase; Humans; Infant;

2001
Functional characterization of intestinal L-carnitine transport.
    The Journal of membrane biology, 2002, Jan-01, Volume: 185, Issue:1

    Topics: Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Cell-Free System; Cells, Culture

2002
Analysis of carnitine biosynthesis metabolites in urine by HPLC-electrospray tandem mass spectrometry.
    Clinical chemistry, 2002, Volume: 48, Issue:6 Pt 1

    Topics: Carnitine; Chromatography, High Pressure Liquid; Deuterium; Humans; Infant, Newborn; Lysine; Male; R

2002
Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:10

    Topics: Calibration; Carnitine; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans

1992
Same-day batch measurement of glycine betaine, carnitine, and other betaines in biological material.
    Analytical biochemistry, 1992, Aug-15, Volume: 205, Issue:1

    Topics: Animals; Betaine; Carnitine; Chromatography, High Pressure Liquid; Humans; Kidney Medulla; Reference

1992
Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method.
    Pediatric research, 1992, Volume: 31, Issue:6

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adolescent; Carnitine; Child; Child, Preschool; Chr

1992