Page last updated: 2024-08-07 12:47:49
Cytochrome P450 1A1
A cytochrome P450 1A1 that is encoded in the genome of rat. [OMA:P00185, PRO:DNx]
Synonyms
CYP1A1;
EC 1.14.14.1;
CYPIA1;
Cytochrome P450 form 6;
Cytochrome P450-C;
Cytochrome P450-P1;
Cytochrome P450MT2;
Hydroperoxy icosatetraenoate dehydratase;
4.2.1.152
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (36)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| dibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 1,000.0000 | 1 | 2 |
| 2,3,7,8-tetrachlorodibenzodioxine | Rattus norvegicus (Norway rat) | EC50 | 0.0100 | 1 | 2 |
| 2,4,2',4'-tetrachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 130.0170 | 1 | 2 |
| octachlorodibenzo-4-dioxin | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 2 |
| 2-chlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 279.8980 | 1 | 2 |
| 1,2,3,4-tetrachlorodibenzodioxin | Rattus norvegicus (Norway rat) | EC50 | 1.3002 | 1 | 2 |
| pcb 118 | Rattus norvegicus (Norway rat) | EC50 | 9.0991 | 1 | 2 |
| 3,4,3',4'-tetrachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 0.7096 | 1 | 2 |
| 2,3,3',4,4'-pentachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 4.2658 | 1 | 2 |
| 2,3,4,5-tetrachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 139.9590 | 1 | 2 |
| 1,2,7,8-tetrachlorodibenzo-p-dioxin | Rattus norvegicus (Norway rat) | EC50 | 0.1600 | 1 | 2 |
| 2,4,5,2',4',5'-hexachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 79.4328 | 1 | 2 |
| 2,3,3',4,4',5-hexachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 7.0958 | 1 | 2 |
| 2,8-dichlorodibenzo-4-dioxin | Rattus norvegicus (Norway rat) | EC50 | 3.1989 | 1 | 2 |
| 1,2,3,4,7,8-hexachlorodibenzodioxin | Rattus norvegicus (Norway rat) | EC50 | 0.2799 | 1 | 2 |
| 1,2,4-trichlorodibenzo-1,4-dioxin | Rattus norvegicus (Norway rat) | EC50 | 13.0017 | 1 | 2 |
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin | Rattus norvegicus (Norway rat) | EC50 | 0.0794 | 1 | 2 |
| 2,3,7,8-tetrabromodibenzo-4-dioxin | Rattus norvegicus (Norway rat) | EC50 | 0.0015 | 1 | 2 |
| 2,3,7,8-tetrachlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 0.0410 | 1 | 2 |
| 2,3,4,7,8-pentachlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 0.0151 | 1 | 2 |
| 1,2,3,7,8-pentachlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 0.0741 | 1 | 2 |
| 1,2,3,4,7,8-hexachlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 0.2301 | 1 | 2 |
| 2,3,4,4'5-pentachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 4.1020 | 1 | 2 |
| 3,4,5,3',4'-pentachlorobiphenyl | Rattus norvegicus (Norway rat) | EC50 | 0.1300 | 1 | 2 |
| 3-chlorodibenzofuran | Rattus norvegicus (Norway rat) | EC50 | 41.9759 | 1 | 2 |
| f 13640 | Rattus norvegicus (Norway rat) | EC50 | 0.0257 | 1 | 1 |
Drugs with Other Measurements