Proteins > Muscarinic acetylcholine receptor M3
Page last updated: 2024-08-07 17:25:20
Muscarinic acetylcholine receptor M3
A muscarinic acetylcholine receptor M3 that is encoded in the genome of mouse. [OMA:Q9ERZ3, PRO:DNx]
Synonyms
Mm3 mAChR
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (11)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pirenzepine | Mus musculus (house mouse) | IC50 | 0.7500 | 1 | 3 |
| pinacidil | Mus musculus (house mouse) | IC50 | 8.9000 | 1 | 3 |
| dexetimide | Mus musculus (house mouse) | IC50 | 0.0033 | 1 | 3 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| aceclidine | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| arecoline | Mus musculus (house mouse) | EC50 | 12.0000 | 1 | 1 |
| carbachol | Mus musculus (house mouse) | EC50 | 9.9000 | 1 | 1 |
| phencyclidine | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| xanomeline | Mus musculus (house mouse) | EC50 | 11.0000 | 1 | 1 |
Drugs with Other Measurements
Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.Journal of medicinal chemistry, , Apr-11, Volume: 40, Issue:8, 1997
Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.Journal of medicinal chemistry, , Apr-11, Volume: 40, Issue:8, 1997
Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.Journal of medicinal chemistry, , Apr-11, Volume: 40, Issue:8, 1997
Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.Journal of medicinal chemistry, , Apr-11, Volume: 40, Issue:8, 1997