A tryptophan 2,3-dioxygenase that is encoded in the genome of mouse. [OMA:P48776, PRO:DNx]
TDO;
EC 1.13.11.11;
Tryptamin 2,3-dioxygenase;
Tryptophan oxygenase;
TO;
TRPO;
Tryptophan pyrrolase;
Tryptophanase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 1,4-naphthohydroquinone | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| 3-cyanoindole | Mus musculus (house mouse) | IC50 | 80.0000 | 1 | 1 |
| indole-3-acetonitrile | Mus musculus (house mouse) | IC50 | 80.0000 | 1 | 1 |
| 5-amino-8-hydroxyquinoline | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| 1-methyltryptophan | Mus musculus (house mouse) | IC50 | 400.0000 | 1 | 1 |
| 4-phenyl-3H-thiazole-2-thione | Mus musculus (house mouse) | IC50 | 80.0000 | 1 | 1 |
| 680c91 | Mus musculus (house mouse) | IC50 | 1.2300 | 2 | 2 |