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Chitinase
[no definition available]
Synonyms
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| rafoxanide | Onchocerca volvulus | IC50 | 0.3400 | 1 | 1 |
| rafoxanide | Onchocerca volvulus | Ki | 0.1300 | 1 | 1 |
| closantel | Onchocerca volvulus | IC50 | 1.6000 | 2 | 2 |
| closantel | Onchocerca volvulus | Ki | 0.4690 | 2 | 2 |
Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting.Journal of medicinal chemistry, , Jul-10, Volume: 57, Issue:13, 2014
Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus.Journal of medicinal chemistry, , Jun-09, Volume: 54, Issue:11, 2011