calmagite: indicator used to measure free magnesium &/or calcium in biological systems; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 2530 |
| CHEMBL ID | 122867 |
| CHEMBL ID | 1980402 |
| SCHEMBL ID | 263650 |
| MeSH ID | M0049693 |
| Synonym |
|---|
| 3-hydroxy-4-((6-hydroxy-m-tolyl)azo)-1-naphthalenesulfonic acid |
| 3-hydroxy-4-(6-hydroxy-m-tolylazo)naphthalene-1-sulphonic acid |
| 1-naphthalenesulfonic acid, 3-hydroxy-4-((2-hydroxy-5-methylphenyl)azo)- |
| 1-naphthalenesulfonic acid, 3-hydroxy-4-((6-hydroxy-m-tolyl)azo)- |
| 1-naphthalenesulfonic acid, 3-hydroxy-4-(2-(2-hydroxy-5-methylphenyl)diazenyl)- |
| nsc 299391 |
| 0a3kvv9hzc , |
| einecs 221-563-0 |
| unii-0a3kvv9hzc |
| NCI60_002511 |
| 1-naphthalenesulfonic acid, 3-hydroxy-4-[(2-hydroxy-5-methylphenyl)azo]- |
| nsc299391 |
| calmagite |
| 1-naphthalenesulfonic acid, 3-hydroxy-4-[(6-hydroxy-m-tolyl)azo]- |
| nsc-299391 |
| 3147-14-6 |
| calmagite, indicator grade |
| 1-(1-hydroxy-4-methyl-2-phenylazo)-2-naphthol-4-sulfonic acid |
| CHEMBL122867 , |
| bdbm50105944 |
| 3-hydroxy-4-(2-hydroxy-5-methyl-phenylazo)-naphthalene-1-sulfonic acid |
| (4z)-4-[(2-hydroxy-5-methylphenyl)hydrazinylidene]-3-oxonaphthalene-1-sulfonic acid |
| FT-0623426 |
| AKOS015903174 |
| 3-hydroxy-4-(2-(2-hydroxy-5-methylphenyl)diazenyl)-1-naphthalenesulfonic acid |
| 3-hydroxy-4-((2-hydroxy-5-methylphenyl)azo)-1-naphthalenesulfoni |
| calmagite [mi] |
| 3-hydroxy-4-((2-hydroxy-5-methylphenyl)azo)-1-naphthalenesulfonic acid |
| SCHEMBL263650 |
| DTXSID8062866 |
| W-202292 |
| CHEMBL1980402 |
| VBRNLOQCBCPPHL-UHFFFAOYSA-N |
| mfcd00011656 |
| 3-hydroxy-4-(2-hydroxy-5-methylphenylazo)naphthalene-1-sulfonic acid |
| (e)-3-hydroxy-4-((2-hydroxy-5-methylphenyl)diazenyl)naphthalene-1-sulfonic acid |
| CS-8214 |
| Q4353551 |
| HY-D0801 |
| AMY22381 |
| 3-hydroxy-4-[(2-hydroxy-5-methylphenyl)diazenyl]naphthalene-1-sulfonic acid |
| T70756 |
| calmagite [metal indicator for ca, mg etc.] |
| MS-25627 |
| 1-naphthalenesulfonic acid,3-hydroxy-4-[(2-hydroxy-5-methylphenyl)azo]- |
| PD078506 |
| PD078507 |
| AKOS040744037 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Thrombopoietin receptor | Homo sapiens (human) | EC50 (µMol) | 3.0000 | 0.0380 | 3.2690 | 10.0000 | AID210168 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| neutrophil homeostasis | Thrombopoietin receptor | Homo sapiens (human) |
| monocyte homeostasis | Thrombopoietin receptor | Homo sapiens (human) |
| positive regulation of lymphocyte proliferation | Thrombopoietin receptor | Homo sapiens (human) |
| cellular response to hypoxia | Thrombopoietin receptor | Homo sapiens (human) |
| positive regulation of platelet formation | Thrombopoietin receptor | Homo sapiens (human) |
| eosinophil homeostasis | Thrombopoietin receptor | Homo sapiens (human) |
| basophil homeostasis | Thrombopoietin receptor | Homo sapiens (human) |
| thrombopoietin-mediated signaling pathway | Thrombopoietin receptor | Homo sapiens (human) |
| immunoglobulin mediated immune response | Thrombopoietin receptor | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| protein binding | Thrombopoietin receptor | Homo sapiens (human) |
| thrombopoietin receptor activity | Thrombopoietin receptor | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| Golgi apparatus | Thrombopoietin receptor | Homo sapiens (human) |
| plasma membrane | Thrombopoietin receptor | Homo sapiens (human) |
| cell surface | Thrombopoietin receptor | Homo sapiens (human) |
| nuclear membrane | Thrombopoietin receptor | Homo sapiens (human) |
| neuronal cell body | Thrombopoietin receptor | Homo sapiens (human) |
| external side of plasma membrane | Thrombopoietin receptor | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID210169 | Thrombopoietin luciferase activity in BAF-3 cells | 2001 | Journal of medicinal chemistry, Oct-25, Volume: 44, Issue:22 | Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis. |
| AID210168 | Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells | 2001 | Journal of medicinal chemistry, Oct-25, Volume: 44, Issue:22 | Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (55.56) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 18 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||