A kynurenine 3-monooxygenase that is encoded in the genome of rat. [OMA:O88867, PRO:DNx]
EC 1.14.13.9;
Kynurenine 3-hydroxylase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| mianserin hydrochloride | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 1 |
| (3-nitrobenzoyl)alanine | Rattus norvegicus (Norway rat) | IC50 | 2.6435 | 4 | 4 |
| sitagliptin | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| ro 61-8048 | Rattus norvegicus (Norway rat) | IC50 | 0.0295 | 2 | 2 |
| ro 61-8048 | Rattus norvegicus (Norway rat) | Ki | 0.0048 | 1 | 1 |
| vildagliptin | Rattus norvegicus (Norway rat) | IC50 | 52.0000 | 1 | 1 |
| talabostat | Rattus norvegicus (Norway rat) | IC50 | 0.0660 | 1 | 1 |