miltefosine has been researched along with Sensitivity and Specificity in 8 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with miltefosine resulted in substantially lower cost-per-cure from a societal and patient perspective, and slightly higher cost-per-cure from a government payer perspective compared to MA." | 1.46 | Cost-effectiveness of meglumine antimoniate versus miltefosine caregiver DOT for the treatment of pediatric cutaneous leishmaniasis. ( Bartlett, AH; Berger, BA; Castro, MDM; Cossio, A; Pho, MT; Prada, S; Saravia, NG, 2017) |
| " This indicates that the bioavailability of He-PC and ET18-OCH3 is not controlled by differences in the uptake of the two drugs, but by differences in their metabolism." | 1.28 | Distribution of hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine in rat tissues during steady-state treatment. ( Eibl, H; Kötting, J; Marschner, N; Unger, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, BA | 1 |
| Cossio, A | 1 |
| Saravia, NG | 1 |
| Castro, MDM | 1 |
| Prada, S | 1 |
| Bartlett, AH | 1 |
| Pho, MT | 1 |
| Godfrey, AR | 1 |
| Jones, L | 1 |
| Davies, M | 1 |
| Townsend, R | 1 |
| Sarkar, A | 1 |
| Mandal, G | 1 |
| Singh, N | 1 |
| Sundar, S | 1 |
| Chatterjee, M | 1 |
| Michel, G | 1 |
| Ferrua, B | 1 |
| Lang, T | 1 |
| Maddugoda, MP | 1 |
| Munro, P | 1 |
| Pomares, C | 1 |
| Lemichez, E | 1 |
| Marty, P | 1 |
| Srivastava, A | 1 |
| Sweat, JM | 1 |
| Azizan, A | 1 |
| Vesely, B | 1 |
| Kyle, DE | 1 |
| Hu, W | 1 |
| Hasebe, K | 1 |
| Tanaka, K | 1 |
| Fritz, JS | 1 |
| Dorlo, TP | 1 |
| Hillebrand, MJ | 1 |
| Rosing, H | 1 |
| Eggelte, TA | 1 |
| de Vries, PJ | 1 |
| Beijnen, JH | 1 |
| Marschner, N | 1 |
| Kötting, J | 1 |
| Eibl, H | 1 |
| Unger, C | 1 |
1 trial available for miltefosine and Sensitivity and Specificity
| Article | Year |
|---|---|
Miltefosine: a novel internal standard approach to lysophospholipid quantitation using LC-MS/MS.
Topics: Algorithms; Blood Chemical Analysis; Chromatography, Liquid; Humans; Internationality; Lysophospholi | 2017 |
7 other studies available for miltefosine and Sensitivity and Specificity
| Article | Year |
|---|---|
Cost-effectiveness of meglumine antimoniate versus miltefosine caregiver DOT for the treatment of pediatric cutaneous leishmaniasis.
Topics: Administration, Oral; Antiprotozoal Agents; Caregivers; Child; Child, Preschool; Cost-Benefit Analys | 2017 |
Flow cytometric determination of intracellular non-protein thiols in Leishmania promastigotes using 5-chloromethyl fluorescein diacetate.
Topics: Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Culture Media, Serum-Free; Flow Cytometry; | 2009 |
Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Female; Leishmania infantum; Leishmania | 2011 |
Real-time PCR to quantify Leishmania donovani in hamsters.
Topics: Amidines; Animals; Antiprotozoal Agents; Cricetinae; Disease Models, Animal; DNA, Kinetoplast; Dose- | 2013 |
Determination of total acidity and of divalent cations by ion chromatography with n-hexadecylphosphocholine as the stationary phase.
Topics: Acids; Cations, Divalent; Chromatography, Liquid; Phosphorylcholine; Sensitivity and Specificity | 2002 |
Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Antiprotozoal Agents; Chromatography, Liquid; Humans; Phosphorylcholine; Sensitivity and Specificity | 2008 |
Distribution of hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine in rat tissues during steady-state treatment.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Densitometry; Drug | 1992 |