Proteins > Transcriptional activator protein LasR
Page last updated: 2024-08-07 23:23:13
Transcriptional activator protein LasR
A protein that is a translation product of the lasR gene in Pseudomonas aeruginosa PAO1. [PRO:DNx, UniProtKB:P25084]
Synonyms
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
Compounds (7)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria.Bioorganic & medicinal chemistry, , 02-01, Volume: 28, Issue:3, 2020
Medicinal chemistry as a conduit for the modulation of quorum sensing.Journal of medicinal chemistry, , Nov-11, Volume: 53, Issue:21, 2010
Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria.Bioorganic & medicinal chemistry, , 02-01, Volume: 28, Issue:3, 2020
Theoretical and structural analysis of the active site of the transcriptional regulators LasR and TraR, using molecular docking methodology for identifying potential analogues of acyl homoserine lactones (AHLs) with anti-quorum sensing activity.European journal of medicinal chemistry, , Volume: 45, Issue:2, 2010
Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria.Bioorganic & medicinal chemistry, , 02-01, Volume: 28, Issue:3, 2020
A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence.Bioorganic & medicinal chemistry, , 10-15, Volume: 26, Issue:19, 2018
Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa.ACS medicinal chemistry letters, , Feb-12, Volume: 6, Issue:2, 2015
Medicinal chemistry as a conduit for the modulation of quorum sensing.Journal of medicinal chemistry, , Nov-11, Volume: 53, Issue:21, 2010