Compounds > 25-hydroxycholesterol
Page last updated: 2024-09-23

25-hydroxycholesterol

Cross-References

ID SourceID
PubMed CID65094
CHEMBL ID169046
CHEBI ID42977
SCHEMBL ID177267
MeSH IDM0051507

Synonyms (44)

Synonym
gtpl2885
(3s,8s,9s,10r,13r,14s,17r)-17-[(1r)-5-hydroxy-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-ol
25-hydroxycholesterol
2140-46-7
cholest-5-ene-3beta,25-diol
NCGC00181327-01
(1s,2r,5s,10s,11s,14r,15r)-14-[(2r)-6-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-7-en-5-ol
bdbm20182
(3beta)-cholest-5-ene-3,25-diol
5-cholestene-3beta,25-diol
CHEBI:42977 ,
DB04705
25-hydroxy-cholesterol
25-ohc
cholest-5-en-3beta,25-diol
LMST01010018
(3s,8s,9s,10r,13r,14s,17r)-17-[(2r)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-ol
CHEMBL169046
cas-2140-46-7
dtxsid5044023 ,
tox21_112790
dtxcid3024023
767jtd2n31 ,
unii-767jtd2n31
25-hydroxycholesterol [mi]
cholest-5-ene-3.beta.,25-diol
5-cholestene-3.beta.,25-diol
SCHEMBL177267
cholest-5-en-3b,25-diol
(3?)-cholest-5-ene-3,25-diol
W-201876
25-hydroxy cholesterol
cholest-5-ene-3?,25-diol
25-hydroxycholesterol, >=98%
F20674
cholest-5-ene-3,25-diol, (3b)-
(3s,8s,9s,10r,13r,14s,17r)-17-((r)-6-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-ol
(3beta,14beta,17alpha)-cholest-5-ene-3,25-diol
Q27071875
HY-113134
CS-0061533
AS-57475
NCGC00181327-02
PD005887

Roles (1)

RoleDescription
human metaboliteAny mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
25-hydroxy steroid
oxysterolAn oxygenated derivative of cholesterol
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (18)

25-hydroxycholesterol is involved in 18 pathway(s), involving a total of 3842 unique proteins and 2972 unique compounds

PathwayProteinsCompounds
Metabolism14961108
Metabolism of lipids500463
Metabolism of steroids111135
Bile acid and bile salt metabolism3171
Synthesis of bile acids and bile salts2068
Biological oxidations150276
Phase I - Functionalization of compounds69175
Cytochrome P450 - arranged by substrate type30110
Endogenous sterols1838
Disease1278231
Diseases of metabolism69121
Metabolic disorders of biological oxidation enzymes647
Defective CYP7B1 causes SPG5A and CBAS304
Cholesterol metabolism with Bloch and Kandutsch-Russell pathways039
SARS-CoV-2 and COVID-19 pathway153
Cholesterol biosynthesis pathway in hepatocytes1137
Oxysterols derived from cholesterol3831
Sterols biosynthesis pathway015

Protein Targets (17)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
TDP1 proteinHomo sapiens (human)Potency27.31710.000811.382244.6684AID686978; AID686979
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency1.34500.01237.983543.2770AID1645841
estrogen nuclear receptor alphaHomo sapiens (human)Potency21.31380.000229.305416,493.5996AID743075
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency8.90580.005612.367736.1254AID624044
Cellular tumor antigen p53Homo sapiens (human)Potency14.96010.002319.595674.0614AID651631
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)IC50 (µMol)0.30000.00000.79498.9000AID83295
Sterol regulatory element-binding protein 2Homo sapiens (human)IC50 (µMol)0.30000.30005.300010.0000AID615677
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Alpha-crystallin B chainHomo sapiens (human)EC50 (µMol)0.32000.32000.87001.4200AID1386480
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)EC50 (µMol)0.63000.47000.76901.1000AID1656767
Integrin beta-3Homo sapiens (human)Kd0.01090.00010.11780.6500AID1647694
Integrin alpha-V Homo sapiens (human)Kd0.01090.01090.06540.1200AID1647694
Nuclear receptor ROR-gammaHomo sapiens (human)EC50 (µMol)0.02000.02000.70359.0000AID1173425; AID1505268; AID1632485
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)EC50 (µMol)10.00000.02100.35851.0000AID1608923; AID1608925
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)EC50 (µMol)10.00000.02100.32421.0000AID1608923
Oxysterols receptor LXR-alphaHomo sapiens (human)EC50 (µMol)1.16000.00010.63026.7100AID101835; AID1797959
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)EC50 (µMol)10.00000.02100.51701.0000AID1608925
Oxysterol-binding protein 2Homo sapiens (human)Kd0.02000.01700.02000.0230AID1802835
NPC1-like intracellular cholesterol transporter 1Homo sapiens (human)EC50 (µMol)3.30001.70003.52508.7000AID1179742
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (336)

Processvia Protein(s)Taxonomy
regulation of programmed cell deathAlpha-crystallin B chainHomo sapiens (human)
cellular response to gamma radiationAlpha-crystallin B chainHomo sapiens (human)
response to hypoxiaAlpha-crystallin B chainHomo sapiens (human)
lens development in camera-type eyeAlpha-crystallin B chainHomo sapiens (human)
protein foldingAlpha-crystallin B chainHomo sapiens (human)
muscle contractionAlpha-crystallin B chainHomo sapiens (human)
tubulin complex assemblyAlpha-crystallin B chainHomo sapiens (human)
muscle organ developmentAlpha-crystallin B chainHomo sapiens (human)
negative regulation of gene expressionAlpha-crystallin B chainHomo sapiens (human)
negative regulation of cell growthAlpha-crystallin B chainHomo sapiens (human)
microtubule polymerization or depolymerizationAlpha-crystallin B chainHomo sapiens (human)
negative regulation of protein-containing complex assemblyAlpha-crystallin B chainHomo sapiens (human)
response to estradiolAlpha-crystallin B chainHomo sapiens (human)
negative regulation of intracellular transportAlpha-crystallin B chainHomo sapiens (human)
response to hydrogen peroxideAlpha-crystallin B chainHomo sapiens (human)
negative regulation of apoptotic processAlpha-crystallin B chainHomo sapiens (human)
negative regulation of DNA-templated transcriptionAlpha-crystallin B chainHomo sapiens (human)
protein stabilizationAlpha-crystallin B chainHomo sapiens (human)
stress-activated MAPK cascadeAlpha-crystallin B chainHomo sapiens (human)
apoptotic process involved in morphogenesisAlpha-crystallin B chainHomo sapiens (human)
negative regulation of amyloid fibril formationAlpha-crystallin B chainHomo sapiens (human)
negative regulation of reactive oxygen species metabolic processAlpha-crystallin B chainHomo sapiens (human)
protein refoldingAlpha-crystallin B chainHomo sapiens (human)
response to heatAlpha-crystallin B chainHomo sapiens (human)
cholesterol biosynthetic process3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
visual learning3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
coenzyme A metabolic process3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
negative regulation of protein catabolic process3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
negative regulation of protein secretion3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
long-term synaptic potentiation3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
regulation of ERK1 and ERK2 cascade3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
negative regulation of amyloid-beta clearance3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
isoprenoid biosynthetic process3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
sterol biosynthetic process3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycle G2/M phase transitionCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
ER overload responseCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
mitophagyCellular tumor antigen p53Homo sapiens (human)
in utero embryonic developmentCellular tumor antigen p53Homo sapiens (human)
somitogenesisCellular tumor antigen p53Homo sapiens (human)
release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
hematopoietic progenitor cell differentiationCellular tumor antigen p53Homo sapiens (human)
T cell proliferation involved in immune responseCellular tumor antigen p53Homo sapiens (human)
B cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
T cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
response to ischemiaCellular tumor antigen p53Homo sapiens (human)
nucleotide-excision repairCellular tumor antigen p53Homo sapiens (human)
double-strand break repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
protein import into nucleusCellular tumor antigen p53Homo sapiens (human)
autophagyCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorCellular tumor antigen p53Homo sapiens (human)
transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
Ras protein signal transductionCellular tumor antigen p53Homo sapiens (human)
gastrulationCellular tumor antigen p53Homo sapiens (human)
neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
protein localizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA replicationCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
determination of adult lifespanCellular tumor antigen p53Homo sapiens (human)
mRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
rRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
response to salt stressCellular tumor antigen p53Homo sapiens (human)
response to inorganic substanceCellular tumor antigen p53Homo sapiens (human)
response to X-rayCellular tumor antigen p53Homo sapiens (human)
response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
positive regulation of gene expressionCellular tumor antigen p53Homo sapiens (human)
cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
viral processCellular tumor antigen p53Homo sapiens (human)
glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
cerebellum developmentCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell growthCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
mitotic G1 DNA damage checkpoint signalingCellular tumor antigen p53Homo sapiens (human)
negative regulation of telomere maintenance via telomeraseCellular tumor antigen p53Homo sapiens (human)
T cell differentiation in thymusCellular tumor antigen p53Homo sapiens (human)
tumor necrosis factor-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
regulation of tissue remodelingCellular tumor antigen p53Homo sapiens (human)
cellular response to UVCellular tumor antigen p53Homo sapiens (human)
multicellular organism growthCellular tumor antigen p53Homo sapiens (human)
positive regulation of mitochondrial membrane permeabilityCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
entrainment of circadian clock by photoperiodCellular tumor antigen p53Homo sapiens (human)
mitochondrial DNA repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
transcription initiation-coupled chromatin remodelingCellular tumor antigen p53Homo sapiens (human)
negative regulation of proteolysisCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of RNA polymerase II transcription preinitiation complex assemblyCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
response to antibioticCellular tumor antigen p53Homo sapiens (human)
fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
circadian behaviorCellular tumor antigen p53Homo sapiens (human)
bone marrow developmentCellular tumor antigen p53Homo sapiens (human)
embryonic organ developmentCellular tumor antigen p53Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationCellular tumor antigen p53Homo sapiens (human)
protein stabilizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of helicase activityCellular tumor antigen p53Homo sapiens (human)
protein tetramerizationCellular tumor antigen p53Homo sapiens (human)
chromosome organizationCellular tumor antigen p53Homo sapiens (human)
neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
hematopoietic stem cell differentiationCellular tumor antigen p53Homo sapiens (human)
negative regulation of glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
type II interferon-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
cardiac septum morphogenesisCellular tumor antigen p53Homo sapiens (human)
positive regulation of programmed necrotic cell deathCellular tumor antigen p53Homo sapiens (human)
protein-containing complex assemblyCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressCellular tumor antigen p53Homo sapiens (human)
thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
necroptotic processCellular tumor antigen p53Homo sapiens (human)
cellular response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
cellular response to xenobiotic stimulusCellular tumor antigen p53Homo sapiens (human)
cellular response to ionizing radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to UV-CCellular tumor antigen p53Homo sapiens (human)
stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
cellular response to actinomycin DCellular tumor antigen p53Homo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
cellular senescenceCellular tumor antigen p53Homo sapiens (human)
replicative senescenceCellular tumor antigen p53Homo sapiens (human)
oxidative stress-induced premature senescenceCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
oligodendrocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of execution phase of apoptosisCellular tumor antigen p53Homo sapiens (human)
negative regulation of mitophagyCellular tumor antigen p53Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of G1 to G0 transitionCellular tumor antigen p53Homo sapiens (human)
negative regulation of miRNA processingCellular tumor antigen p53Homo sapiens (human)
negative regulation of glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
negative regulation of pentose-phosphate shuntCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
regulation of fibroblast apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
positive regulation of cellular senescenceCellular tumor antigen p53Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
negative regulation of low-density lipoprotein receptor activityIntegrin beta-3Homo sapiens (human)
positive regulation of protein phosphorylationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
cell-substrate junction assemblyIntegrin beta-3Homo sapiens (human)
cell adhesionIntegrin beta-3Homo sapiens (human)
cell-matrix adhesionIntegrin beta-3Homo sapiens (human)
integrin-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
embryo implantationIntegrin beta-3Homo sapiens (human)
blood coagulationIntegrin beta-3Homo sapiens (human)
positive regulation of endothelial cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of gene expressionIntegrin beta-3Homo sapiens (human)
negative regulation of macrophage derived foam cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast migrationIntegrin beta-3Homo sapiens (human)
negative regulation of lipid storageIntegrin beta-3Homo sapiens (human)
response to activityIntegrin beta-3Homo sapiens (human)
smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell migrationIntegrin beta-3Homo sapiens (human)
platelet activationIntegrin beta-3Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
cell-substrate adhesionIntegrin beta-3Homo sapiens (human)
activation of protein kinase activityIntegrin beta-3Homo sapiens (human)
negative regulation of lipid transportIntegrin beta-3Homo sapiens (human)
regulation of protein localizationIntegrin beta-3Homo sapiens (human)
regulation of actin cytoskeleton organizationIntegrin beta-3Homo sapiens (human)
cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of cell adhesion mediated by integrinIntegrin beta-3Homo sapiens (human)
positive regulation of osteoblast proliferationIntegrin beta-3Homo sapiens (human)
heterotypic cell-cell adhesionIntegrin beta-3Homo sapiens (human)
substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
tube developmentIntegrin beta-3Homo sapiens (human)
wound healing, spreading of epidermal cellsIntegrin beta-3Homo sapiens (human)
cellular response to platelet-derived growth factor stimulusIntegrin beta-3Homo sapiens (human)
apolipoprotein A-I-mediated signaling pathwayIntegrin beta-3Homo sapiens (human)
wound healingIntegrin beta-3Homo sapiens (human)
apoptotic cell clearanceIntegrin beta-3Homo sapiens (human)
regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
positive regulation of angiogenesisIntegrin beta-3Homo sapiens (human)
positive regulation of bone resorptionIntegrin beta-3Homo sapiens (human)
symbiont entry into host cellIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
positive regulation of fibroblast proliferationIntegrin beta-3Homo sapiens (human)
mesodermal cell differentiationIntegrin beta-3Homo sapiens (human)
positive regulation of smooth muscle cell proliferationIntegrin beta-3Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationIntegrin beta-3Homo sapiens (human)
negative regulation of lipoprotein metabolic processIntegrin beta-3Homo sapiens (human)
negative chemotaxisIntegrin beta-3Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosolIntegrin beta-3Homo sapiens (human)
regulation of serotonin uptakeIntegrin beta-3Homo sapiens (human)
angiogenesis involved in wound healingIntegrin beta-3Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascadeIntegrin beta-3Homo sapiens (human)
platelet aggregationIntegrin beta-3Homo sapiens (human)
cellular response to mechanical stimulusIntegrin beta-3Homo sapiens (human)
cellular response to xenobiotic stimulusIntegrin beta-3Homo sapiens (human)
positive regulation of glomerular mesangial cell proliferationIntegrin beta-3Homo sapiens (human)
blood coagulation, fibrin clot formationIntegrin beta-3Homo sapiens (human)
maintenance of postsynaptic specialization structureIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor internalizationIntegrin beta-3Homo sapiens (human)
regulation of postsynaptic neurotransmitter receptor diffusion trappingIntegrin beta-3Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreadingIntegrin beta-3Homo sapiens (human)
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathwayIntegrin beta-3Homo sapiens (human)
regulation of trophoblast cell migrationIntegrin beta-3Homo sapiens (human)
regulation of extracellular matrix organizationIntegrin beta-3Homo sapiens (human)
cellular response to insulin-like growth factor stimulusIntegrin beta-3Homo sapiens (human)
negative regulation of endothelial cell apoptotic processIntegrin beta-3Homo sapiens (human)
positive regulation of T cell migrationIntegrin beta-3Homo sapiens (human)
cell migrationIntegrin beta-3Homo sapiens (human)
negative regulation of low-density lipoprotein receptor activityIntegrin alpha-V Homo sapiens (human)
angiogenesisIntegrin alpha-V Homo sapiens (human)
vasculogenesisIntegrin alpha-V Homo sapiens (human)
cell adhesionIntegrin alpha-V Homo sapiens (human)
cell-matrix adhesionIntegrin alpha-V Homo sapiens (human)
positive regulation of cytosolic calcium ion concentrationIntegrin alpha-V Homo sapiens (human)
integrin-mediated signaling pathwayIntegrin alpha-V Homo sapiens (human)
positive regulation of cell population proliferationIntegrin alpha-V Homo sapiens (human)
negative regulation of macrophage derived foam cell differentiationIntegrin alpha-V Homo sapiens (human)
negative regulation of lipid storageIntegrin alpha-V Homo sapiens (human)
cell migrationIntegrin alpha-V Homo sapiens (human)
positive regulation of cell migrationIntegrin alpha-V Homo sapiens (human)
cell-substrate adhesionIntegrin alpha-V Homo sapiens (human)
negative regulation of lipid transportIntegrin alpha-V Homo sapiens (human)
cell adhesion mediated by integrinIntegrin alpha-V Homo sapiens (human)
positive regulation of osteoblast proliferationIntegrin alpha-V Homo sapiens (human)
heterotypic cell-cell adhesionIntegrin alpha-V Homo sapiens (human)
substrate adhesion-dependent cell spreadingIntegrin alpha-V Homo sapiens (human)
wound healing, spreading of epidermal cellsIntegrin alpha-V Homo sapiens (human)
endodermal cell differentiationIntegrin alpha-V Homo sapiens (human)
apolipoprotein A-I-mediated signaling pathwayIntegrin alpha-V Homo sapiens (human)
apoptotic cell clearanceIntegrin alpha-V Homo sapiens (human)
positive regulation of cell adhesionIntegrin alpha-V Homo sapiens (human)
symbiont entry into host cellIntegrin alpha-V Homo sapiens (human)
negative regulation of lipoprotein metabolic processIntegrin alpha-V Homo sapiens (human)
regulation of phagocytosisIntegrin alpha-V Homo sapiens (human)
negative chemotaxisIntegrin alpha-V Homo sapiens (human)
positive regulation of small GTPase mediated signal transductionIntegrin alpha-V Homo sapiens (human)
ERK1 and ERK2 cascadeIntegrin alpha-V Homo sapiens (human)
calcium ion transmembrane transportIntegrin alpha-V Homo sapiens (human)
transforming growth factor beta productionIntegrin alpha-V Homo sapiens (human)
entry into host cell by a symbiont-containing vacuoleIntegrin alpha-V Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligandIntegrin alpha-V Homo sapiens (human)
positive regulation of intracellular signal transductionIntegrin alpha-V Homo sapiens (human)
negative regulation of entry of bacterium into host cellIntegrin alpha-V Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathwayIntegrin alpha-V Homo sapiens (human)
cell-cell adhesionIntegrin alpha-V Homo sapiens (human)
negative regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
xenobiotic metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of glucose metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of steroid metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
intracellular receptor signaling pathwayNuclear receptor ROR-gammaHomo sapiens (human)
circadian regulation of gene expressionNuclear receptor ROR-gammaHomo sapiens (human)
cellular response to sterolNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of circadian rhythmNuclear receptor ROR-gammaHomo sapiens (human)
regulation of fat cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of DNA-templated transcriptionNuclear receptor ROR-gammaHomo sapiens (human)
adipose tissue developmentNuclear receptor ROR-gammaHomo sapiens (human)
T-helper 17 cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
cellular response to amyloid-betaGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
monoatomic cation transportGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
brain developmentGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
visual learningGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of calcium ion transport into cytosolGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
propylene metabolic processGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calcium-mediated signalingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
ionotropic glutamate receptor signaling pathwayGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
regulation of membrane potentialGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
response to ethanolGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of transcription by RNA polymerase IIGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
regulation of synaptic plasticityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
regulation of neuronal synaptic plasticityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
protein heterotetramerizationGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergicGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calcium ion homeostasisGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calcium ion transmembrane import into cytosolGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
excitatory chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of reactive oxygen species biosynthetic processGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
regulation of monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
response to glycineGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
positive regulation of cholesterol storageSterol regulatory element-binding protein 2Homo sapiens (human)
negative regulation of cholesterol effluxSterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of transcription by RNA polymerase IISterol regulatory element-binding protein 2Homo sapiens (human)
negative regulation of transcription by RNA polymerase IISterol regulatory element-binding protein 2Homo sapiens (human)
lipid metabolic processSterol regulatory element-binding protein 2Homo sapiens (human)
cholesterol metabolic processSterol regulatory element-binding protein 2Homo sapiens (human)
regulation of Notch signaling pathwaySterol regulatory element-binding protein 2Homo sapiens (human)
cellular response to starvationSterol regulatory element-binding protein 2Homo sapiens (human)
SREBP signaling pathwaySterol regulatory element-binding protein 2Homo sapiens (human)
cholesterol homeostasisSterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of cholesterol biosynthetic processSterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of transcription by RNA polymerase IISterol regulatory element-binding protein 2Homo sapiens (human)
cellular response to low-density lipoprotein particle stimulusSterol regulatory element-binding protein 2Homo sapiens (human)
cellular response to laminar fluid shear stressSterol regulatory element-binding protein 2Homo sapiens (human)
regulation of mitophagySterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of miRNA transcriptionSterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of protein targeting to mitochondrionSterol regulatory element-binding protein 2Homo sapiens (human)
positive regulation of cholesterol storageSterol regulatory element-binding protein 2Homo sapiens (human)
cellular response to amyloid-betaGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
startle responseGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
response to amphetamineGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
glutamate receptor signaling pathwayGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
brain developmentGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
learning or memoryGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
memoryGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
visual learningGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
response to xenobiotic stimulusGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
response to woundingGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
sensory perception of painGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
calcium-mediated signalingGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
neurogenesisGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
protein catabolic processGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
sleepGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
directional locomotionGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
ionotropic glutamate receptor signaling pathwayGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
negative regulation of protein catabolic processGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
dopamine metabolic processGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
serotonin metabolic processGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
positive regulation of apoptotic processGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
response to ethanolGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
regulation of synaptic plasticityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
regulation of neuronal synaptic plasticityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
positive regulation of synaptic transmission, glutamatergicGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
activation of cysteine-type endopeptidase activityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
calcium ion transmembrane import into cytosolGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
excitatory chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
protein localization to postsynaptic membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
regulation of monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
positive regulation of excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
synaptic transmission, glutamatergicGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
long-term synaptic potentiationGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
negative regulation of transcription by RNA polymerase IIOxysterols receptor LXR-alphaHomo sapiens (human)
hormone-mediated signaling pathwayOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of macrophage derived foam cell differentiationOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of triglyceride biosynthetic processOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of cholesterol effluxOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of cholesterol storageOxysterols receptor LXR-alphaHomo sapiens (human)
intracellular receptor signaling pathwayOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of lipid transportOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of cholesterol transportOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of transporter activityOxysterols receptor LXR-alphaHomo sapiens (human)
response to progesteroneOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of toll-like receptor 4 signaling pathwayOxysterols receptor LXR-alphaHomo sapiens (human)
phosphatidylcholine acyl-chain remodelingOxysterols receptor LXR-alphaHomo sapiens (human)
cholesterol homeostasisOxysterols receptor LXR-alphaHomo sapiens (human)
regulation of circadian rhythmOxysterols receptor LXR-alphaHomo sapiens (human)
mRNA transcription by RNA polymerase IIOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of macrophage activationOxysterols receptor LXR-alphaHomo sapiens (human)
apoptotic cell clearanceOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of fatty acid biosynthetic processOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of proteolysisOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of DNA-templated transcriptionOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of transcription by RNA polymerase IIOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of lipid biosynthetic processOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of pinocytosisOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of inflammatory responseOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of lipoprotein lipase activityOxysterols receptor LXR-alphaHomo sapiens (human)
positive regulation of protein metabolic processOxysterols receptor LXR-alphaHomo sapiens (human)
lipid homeostasisOxysterols receptor LXR-alphaHomo sapiens (human)
sterol homeostasisOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of type II interferon-mediated signaling pathwayOxysterols receptor LXR-alphaHomo sapiens (human)
triglyceride homeostasisOxysterols receptor LXR-alphaHomo sapiens (human)
cellular response to lipopolysaccharideOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of pancreatic juice secretionOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of secretion of lysosomal enzymesOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of cold-induced thermogenesisOxysterols receptor LXR-alphaHomo sapiens (human)
negative regulation of response to endoplasmic reticulum stressOxysterols receptor LXR-alphaHomo sapiens (human)
cell differentiationOxysterols receptor LXR-alphaHomo sapiens (human)
glutamate receptor signaling pathwayGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
brain developmentGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
learning or memoryGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
calcium-mediated signalingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
ionotropic glutamate receptor signaling pathwayGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
response to ethanolGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
regulation of synaptic plasticityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
regulation of neuronal synaptic plasticityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
protein heterotetramerizationGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
positive regulation of synaptic transmission, glutamatergicGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
calcium ion transmembrane import into cytosolGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
excitatory chemical synaptic transmissionGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
regulation of presynaptic membrane potentialGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
negative regulation of dendritic spine maintenanceGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
regulation of monoatomic cation transmembrane transportGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
positive regulation of excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
positive regulation of cysteine-type endopeptidase activityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
long-term synaptic potentiationGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
synaptic transmission, glutamatergicGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
excitatory postsynaptic potentialGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
lipid transportOxysterol-binding protein 2Homo sapiens (human)
spermatid developmentOxysterol-binding protein 2Homo sapiens (human)
cholesterol biosynthetic processNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
intestinal cholesterol absorptionNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
cholesterol transportNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
lipoprotein metabolic processNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
vitamin E metabolic processNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
vitamin transportNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
cellular response to sterol depletionNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
cholesterol homeostasisNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (89)

Processvia Protein(s)Taxonomy
amyloid-beta bindingAlpha-crystallin B chainHomo sapiens (human)
structural molecule activityAlpha-crystallin B chainHomo sapiens (human)
structural constituent of eye lensAlpha-crystallin B chainHomo sapiens (human)
protein bindingAlpha-crystallin B chainHomo sapiens (human)
microtubule bindingAlpha-crystallin B chainHomo sapiens (human)
identical protein bindingAlpha-crystallin B chainHomo sapiens (human)
protein homodimerization activityAlpha-crystallin B chainHomo sapiens (human)
protein-containing complex bindingAlpha-crystallin B chainHomo sapiens (human)
metal ion bindingAlpha-crystallin B chainHomo sapiens (human)
unfolded protein bindingAlpha-crystallin B chainHomo sapiens (human)
hydroxymethylglutaryl-CoA reductase (NADPH) activity3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
protein binding3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
GTPase regulator activity3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
NADPH binding3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
coenzyme A binding3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
transcription cis-regulatory region bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
core promoter sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
TFIID-class transcription factor complex bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
protease bindingCellular tumor antigen p53Homo sapiens (human)
p53 bindingCellular tumor antigen p53Homo sapiens (human)
DNA bindingCellular tumor antigen p53Homo sapiens (human)
chromatin bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activityCellular tumor antigen p53Homo sapiens (human)
mRNA 3'-UTR bindingCellular tumor antigen p53Homo sapiens (human)
copper ion bindingCellular tumor antigen p53Homo sapiens (human)
protein bindingCellular tumor antigen p53Homo sapiens (human)
zinc ion bindingCellular tumor antigen p53Homo sapiens (human)
enzyme bindingCellular tumor antigen p53Homo sapiens (human)
receptor tyrosine kinase bindingCellular tumor antigen p53Homo sapiens (human)
ubiquitin protein ligase bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase regulator activityCellular tumor antigen p53Homo sapiens (human)
ATP-dependent DNA/DNA annealing activityCellular tumor antigen p53Homo sapiens (human)
identical protein bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase bindingCellular tumor antigen p53Homo sapiens (human)
protein heterodimerization activityCellular tumor antigen p53Homo sapiens (human)
protein-folding chaperone bindingCellular tumor antigen p53Homo sapiens (human)
protein phosphatase 2A bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingCellular tumor antigen p53Homo sapiens (human)
14-3-3 protein bindingCellular tumor antigen p53Homo sapiens (human)
MDM2/MDM4 family protein bindingCellular tumor antigen p53Homo sapiens (human)
disordered domain specific bindingCellular tumor antigen p53Homo sapiens (human)
general transcription initiation factor bindingCellular tumor antigen p53Homo sapiens (human)
molecular function activator activityCellular tumor antigen p53Homo sapiens (human)
promoter-specific chromatin bindingCellular tumor antigen p53Homo sapiens (human)
fibroblast growth factor bindingIntegrin beta-3Homo sapiens (human)
C-X3-C chemokine bindingIntegrin beta-3Homo sapiens (human)
insulin-like growth factor I bindingIntegrin beta-3Homo sapiens (human)
neuregulin bindingIntegrin beta-3Homo sapiens (human)
virus receptor activityIntegrin beta-3Homo sapiens (human)
fibronectin bindingIntegrin beta-3Homo sapiens (human)
protease bindingIntegrin beta-3Homo sapiens (human)
protein disulfide isomerase activityIntegrin beta-3Homo sapiens (human)
protein kinase C bindingIntegrin beta-3Homo sapiens (human)
platelet-derived growth factor receptor bindingIntegrin beta-3Homo sapiens (human)
integrin bindingIntegrin beta-3Homo sapiens (human)
protein bindingIntegrin beta-3Homo sapiens (human)
coreceptor activityIntegrin beta-3Homo sapiens (human)
enzyme bindingIntegrin beta-3Homo sapiens (human)
identical protein bindingIntegrin beta-3Homo sapiens (human)
vascular endothelial growth factor receptor 2 bindingIntegrin beta-3Homo sapiens (human)
metal ion bindingIntegrin beta-3Homo sapiens (human)
cell adhesion molecule bindingIntegrin beta-3Homo sapiens (human)
extracellular matrix bindingIntegrin beta-3Homo sapiens (human)
fibrinogen bindingIntegrin beta-3Homo sapiens (human)
opsonin bindingIntegrin alpha-V Homo sapiens (human)
protein kinase C bindingIntegrin alpha-V Homo sapiens (human)
fibroblast growth factor bindingIntegrin alpha-V Homo sapiens (human)
C-X3-C chemokine bindingIntegrin alpha-V Homo sapiens (human)
insulin-like growth factor I bindingIntegrin alpha-V Homo sapiens (human)
neuregulin bindingIntegrin alpha-V Homo sapiens (human)
virus receptor activityIntegrin alpha-V Homo sapiens (human)
fibronectin bindingIntegrin alpha-V Homo sapiens (human)
protease bindingIntegrin alpha-V Homo sapiens (human)
integrin bindingIntegrin alpha-V Homo sapiens (human)
voltage-gated calcium channel activityIntegrin alpha-V Homo sapiens (human)
protein bindingIntegrin alpha-V Homo sapiens (human)
coreceptor activityIntegrin alpha-V Homo sapiens (human)
metal ion bindingIntegrin alpha-V Homo sapiens (human)
transforming growth factor beta bindingIntegrin alpha-V Homo sapiens (human)
extracellular matrix bindingIntegrin alpha-V Homo sapiens (human)
extracellular matrix protein bindingIntegrin alpha-V Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
protein bindingNuclear receptor ROR-gammaHomo sapiens (human)
oxysterol bindingNuclear receptor ROR-gammaHomo sapiens (human)
zinc ion bindingNuclear receptor ROR-gammaHomo sapiens (human)
ligand-activated transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
sequence-specific double-stranded DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
nuclear receptor activityNuclear receptor ROR-gammaHomo sapiens (human)
NMDA glutamate receptor activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calcium channel activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
amyloid-beta bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
NMDA glutamate receptor activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calcium ion bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
protein bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
calmodulin bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
glycine bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
glutamate bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
glutamate-gated calcium ion channel activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
protein-containing complex bindingGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
signaling receptor activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
ligand-gated monoatomic ion channel activityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
C-8 sterol isomerase activitySterol regulatory element-binding protein 2Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingSterol regulatory element-binding protein 2Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificSterol regulatory element-binding protein 2Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificSterol regulatory element-binding protein 2Homo sapiens (human)
protein bindingSterol regulatory element-binding protein 2Homo sapiens (human)
protein dimerization activitySterol regulatory element-binding protein 2Homo sapiens (human)
E-box bindingSterol regulatory element-binding protein 2Homo sapiens (human)
sequence-specific double-stranded DNA bindingSterol regulatory element-binding protein 2Homo sapiens (human)
amyloid-beta bindingGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
NMDA glutamate receptor activityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
protein bindingGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
zinc ion bindingGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
glutamate-gated calcium ion channel activityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potentialGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
transcription cis-regulatory region bindingOxysterols receptor LXR-alphaHomo sapiens (human)
transcription cis-regulatory region bindingOxysterols receptor LXR-alphaHomo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificOxysterols receptor LXR-alphaHomo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificOxysterols receptor LXR-alphaHomo sapiens (human)
DNA bindingOxysterols receptor LXR-alphaHomo sapiens (human)
nuclear receptor activityOxysterols receptor LXR-alphaHomo sapiens (human)
protein bindingOxysterols receptor LXR-alphaHomo sapiens (human)
zinc ion bindingOxysterols receptor LXR-alphaHomo sapiens (human)
cholesterol bindingOxysterols receptor LXR-alphaHomo sapiens (human)
chromatin DNA bindingOxysterols receptor LXR-alphaHomo sapiens (human)
sterol response element bindingOxysterols receptor LXR-alphaHomo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingOxysterols receptor LXR-alphaHomo sapiens (human)
amyloid-beta bindingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
NMDA glutamate receptor activityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
protein bindingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
zinc ion bindingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
glycine bindingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
glutamate bindingGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
glutamate-gated calcium ion channel activityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potentialGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potentialGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
protein bindingOxysterol-binding protein 2Homo sapiens (human)
cholesterol bindingOxysterol-binding protein 2Homo sapiens (human)
protein bindingNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
vitamin E bindingNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
cholesterol bindingNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
small GTPase bindingNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
myosin V bindingNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
protein homodimerization activityNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (83)

Processvia Protein(s)Taxonomy
nucleusAlpha-crystallin B chainHomo sapiens (human)
nucleoplasmAlpha-crystallin B chainHomo sapiens (human)
cytoplasmAlpha-crystallin B chainHomo sapiens (human)
mitochondrionAlpha-crystallin B chainHomo sapiens (human)
lysosomeAlpha-crystallin B chainHomo sapiens (human)
cytosolAlpha-crystallin B chainHomo sapiens (human)
cell surfaceAlpha-crystallin B chainHomo sapiens (human)
Z discAlpha-crystallin B chainHomo sapiens (human)
axonAlpha-crystallin B chainHomo sapiens (human)
M bandAlpha-crystallin B chainHomo sapiens (human)
actin filament bundleAlpha-crystallin B chainHomo sapiens (human)
dendritic spineAlpha-crystallin B chainHomo sapiens (human)
perikaryonAlpha-crystallin B chainHomo sapiens (human)
extracellular exosomeAlpha-crystallin B chainHomo sapiens (human)
synaptic membraneAlpha-crystallin B chainHomo sapiens (human)
cardiac myofibrilAlpha-crystallin B chainHomo sapiens (human)
protein-containing complexAlpha-crystallin B chainHomo sapiens (human)
nucleusAlpha-crystallin B chainHomo sapiens (human)
cytoplasmAlpha-crystallin B chainHomo sapiens (human)
peroxisomal membrane3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
endoplasmic reticulum3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
endoplasmic reticulum membrane3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
endoplasmic reticulum membrane3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
peroxisomal membrane3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)
nuclear bodyCellular tumor antigen p53Homo sapiens (human)
nucleusCellular tumor antigen p53Homo sapiens (human)
nucleoplasmCellular tumor antigen p53Homo sapiens (human)
replication forkCellular tumor antigen p53Homo sapiens (human)
nucleolusCellular tumor antigen p53Homo sapiens (human)
cytoplasmCellular tumor antigen p53Homo sapiens (human)
mitochondrionCellular tumor antigen p53Homo sapiens (human)
mitochondrial matrixCellular tumor antigen p53Homo sapiens (human)
endoplasmic reticulumCellular tumor antigen p53Homo sapiens (human)
centrosomeCellular tumor antigen p53Homo sapiens (human)
cytosolCellular tumor antigen p53Homo sapiens (human)
nuclear matrixCellular tumor antigen p53Homo sapiens (human)
PML bodyCellular tumor antigen p53Homo sapiens (human)
transcription repressor complexCellular tumor antigen p53Homo sapiens (human)
site of double-strand breakCellular tumor antigen p53Homo sapiens (human)
germ cell nucleusCellular tumor antigen p53Homo sapiens (human)
chromatinCellular tumor antigen p53Homo sapiens (human)
transcription regulator complexCellular tumor antigen p53Homo sapiens (human)
protein-containing complexCellular tumor antigen p53Homo sapiens (human)
glutamatergic synapseIntegrin beta-3Homo sapiens (human)
nucleusIntegrin beta-3Homo sapiens (human)
nucleoplasmIntegrin beta-3Homo sapiens (human)
plasma membraneIntegrin beta-3Homo sapiens (human)
cell-cell junctionIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
external side of plasma membraneIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
apical plasma membraneIntegrin beta-3Homo sapiens (human)
platelet alpha granule membraneIntegrin beta-3Homo sapiens (human)
lamellipodium membraneIntegrin beta-3Homo sapiens (human)
filopodium membraneIntegrin beta-3Homo sapiens (human)
microvillus membraneIntegrin beta-3Homo sapiens (human)
ruffle membraneIntegrin beta-3Homo sapiens (human)
integrin alphav-beta3 complexIntegrin beta-3Homo sapiens (human)
melanosomeIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
postsynaptic membraneIntegrin beta-3Homo sapiens (human)
extracellular exosomeIntegrin beta-3Homo sapiens (human)
integrin alphaIIb-beta3 complexIntegrin beta-3Homo sapiens (human)
glycinergic synapseIntegrin beta-3Homo sapiens (human)
integrin complexIntegrin beta-3Homo sapiens (human)
protein-containing complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-HMGB1 complexIntegrin beta-3Homo sapiens (human)
receptor complexIntegrin beta-3Homo sapiens (human)
alphav-beta3 integrin-vitronectin complexIntegrin beta-3Homo sapiens (human)
alpha9-beta1 integrin-ADAM8 complexIntegrin beta-3Homo sapiens (human)
focal adhesionIntegrin beta-3Homo sapiens (human)
cell surfaceIntegrin beta-3Homo sapiens (human)
synapseIntegrin beta-3Homo sapiens (human)
cytosolIntegrin alpha-V Homo sapiens (human)
plasma membraneIntegrin alpha-V Homo sapiens (human)
focal adhesionIntegrin alpha-V Homo sapiens (human)
cell surfaceIntegrin alpha-V Homo sapiens (human)
membraneIntegrin alpha-V Homo sapiens (human)
lamellipodium membraneIntegrin alpha-V Homo sapiens (human)
filopodium membraneIntegrin alpha-V Homo sapiens (human)
microvillus membraneIntegrin alpha-V Homo sapiens (human)
ruffle membraneIntegrin alpha-V Homo sapiens (human)
integrin alphav-beta1 complexIntegrin alpha-V Homo sapiens (human)
integrin alphav-beta3 complexIntegrin alpha-V Homo sapiens (human)
integrin alphav-beta5 complexIntegrin alpha-V Homo sapiens (human)
integrin alphav-beta6 complexIntegrin alpha-V Homo sapiens (human)
integrin alphav-beta8 complexIntegrin alpha-V Homo sapiens (human)
specific granule membraneIntegrin alpha-V Homo sapiens (human)
phagocytic vesicleIntegrin alpha-V Homo sapiens (human)
extracellular exosomeIntegrin alpha-V Homo sapiens (human)
integrin complexIntegrin alpha-V Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complexIntegrin alpha-V Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complexIntegrin alpha-V Homo sapiens (human)
alphav-beta3 integrin-HMGB1 complexIntegrin alpha-V Homo sapiens (human)
external side of plasma membraneIntegrin alpha-V Homo sapiens (human)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
nucleoplasmNuclear receptor ROR-gammaHomo sapiens (human)
nuclear bodyNuclear receptor ROR-gammaHomo sapiens (human)
chromatinNuclear receptor ROR-gammaHomo sapiens (human)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
cytoplasmGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
synaptic vesicleGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
cell surfaceGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
postsynaptic densityGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
NMDA selective glutamate receptor complexGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
dendriteGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
neuron projectionGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
synaptic cleftGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
terminal boutonGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
dendritic spineGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
synapseGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
postsynaptic membraneGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
excitatory synapseGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
synaptic membraneGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
synapseGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
neuron projectionGlutamate receptor ionotropic, NMDA 1Homo sapiens (human)
Golgi membraneSterol regulatory element-binding protein 2Homo sapiens (human)
nucleusSterol regulatory element-binding protein 2Homo sapiens (human)
nucleoplasmSterol regulatory element-binding protein 2Homo sapiens (human)
cytoplasmSterol regulatory element-binding protein 2Homo sapiens (human)
endoplasmic reticulumSterol regulatory element-binding protein 2Homo sapiens (human)
endoplasmic reticulum membraneSterol regulatory element-binding protein 2Homo sapiens (human)
cytosolSterol regulatory element-binding protein 2Homo sapiens (human)
ER to Golgi transport vesicle membraneSterol regulatory element-binding protein 2Homo sapiens (human)
intracellular membrane-bounded organelleSterol regulatory element-binding protein 2Homo sapiens (human)
chromatinSterol regulatory element-binding protein 2Homo sapiens (human)
SREBP-SCAP-Insig complexSterol regulatory element-binding protein 2Homo sapiens (human)
nucleusSterol regulatory element-binding protein 2Homo sapiens (human)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
synaptic vesicleGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
cell surfaceGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
postsynaptic densityGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
NMDA selective glutamate receptor complexGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
cytoplasmic vesicle membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
presynaptic membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
dendritic spineGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
postsynaptic membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
synaptic membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
glutamatergic synapseGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
postsynaptic density membraneGlutamate receptor ionotropic, NMDA 2AHomo sapiens (human)
nucleusOxysterols receptor LXR-alphaHomo sapiens (human)
nucleoplasmOxysterols receptor LXR-alphaHomo sapiens (human)
cytoplasmOxysterols receptor LXR-alphaHomo sapiens (human)
cytosolOxysterols receptor LXR-alphaHomo sapiens (human)
RNA polymerase II transcription regulator complexOxysterols receptor LXR-alphaHomo sapiens (human)
chromatinOxysterols receptor LXR-alphaHomo sapiens (human)
receptor complexOxysterols receptor LXR-alphaHomo sapiens (human)
nucleusOxysterols receptor LXR-alphaHomo sapiens (human)
cytoplasmGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
lysosomeGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
late endosomeGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
endoplasmic reticulum membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
cytoskeletonGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
cell surfaceGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
postsynaptic densityGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
NMDA selective glutamate receptor complexGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
neuron projectionGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
postsynaptic membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
synaptic membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
plasma membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
postsynaptic density membraneGlutamate receptor ionotropic, NMDA 2BHomo sapiens (human)
apical dendriteOxysterol-binding protein 2Homo sapiens (human)
cytosolOxysterol-binding protein 2Homo sapiens (human)
plasma membraneOxysterol-binding protein 2Homo sapiens (human)
perinuclear endoplasmic reticulumOxysterol-binding protein 2Homo sapiens (human)
plasma membraneNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
apical plasma membraneNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
cytoplasmic vesicle membraneNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
plasma membraneNPC1-like intracellular cholesterol transporter 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (60)

Assay IDTitleYearJournalArticle
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID695019Selectivity ratio of agonist activity at Hh receptor over agonist activity at LXR in mouse C3H10T1/2 cells2012ACS medicinal chemistry letters, Oct-11, Volume: 3, Issue:10
Structure-activity relationships for side chain oxysterol agonists of the hedgehog signaling pathway.
AID738363Cytotoxicity against human HepG2 cells assessed as cell viability up to 2 uM after 48 hrs by MTT assay2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID1386525Inhibition of beta-crystallin B2 V187E mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1647694Binding affinity to human integrin alphavbeta3 by surface plasmon resonance method2020Journal of medicinal chemistry, 06-11, Volume: 63, Issue:11
Insights into Protein-Ligand Interactions in Integrin Complexes: Advances in Structure Determinations.
AID1608926Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method relati2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1608925Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1608938Volume of distribution at steady state in rat2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1179742Binding affinity to FLAG/tGFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as localization after 24 hrs by fluorescence microscopy2014Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15
Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.
AID509545Agonist activity at hedgehog receptor2010Bioorganic & medicinal chemistry, Sep-15, Volume: 18, Issue:18
Modulators of the hedgehog signaling pathway.
AID780282Cytotoxicity against african green monkey Vero cells by tetrazolium dye reduction assay2013Bioorganic & medicinal chemistry letters, Nov-15, Volume: 23, Issue:22
Inhibitory effect of oxygenated cholestan-3β-ol derivatives on the growth of Mycobacterium tuberculosis.
AID1590319Induction of OSBP localization in golgi apparatus of human HeLa cells assessed as increase in colocalization of 58K golgi protein at 0.5 uM incubated for 30 mins by immunofluorescence imaging method2019Bioorganic & medicinal chemistry letters, 07-15, Volume: 29, Issue:14
Anticancer saponin OSW-1 is a novel class of selective Golgi stress inducer.
AID738369Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID1070447Activation of LXRalpha in human HepG2 cells at 25 uM after 24 hrs by luciferase reporter gene assay relative to vehicle-treated control2014Journal of natural products, Mar-28, Volume: 77, Issue:3
Octulosonic acid derivatives from Roman chamomile (Chamaemelum nobile) with activities against inflammation and metabolic disorder.
AID1173425Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysis2014Bioorganic & medicinal chemistry letters, Dec-15, Volume: 24, Issue:24
A reversed sulfonamide series of selective RORc inverse agonists.
AID101835Concentration required for half maximal activity was calculated in human nuclear oxysterol receptor liver X receptor-alpha in LiSA.2001Journal of medicinal chemistry, Mar-15, Volume: 44, Issue:6
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
AID1386474Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 0.4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1386523Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1386524Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1656767Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase reporter assay2020Bioorganic & medicinal chemistry, 02-01, Volume: 28, Issue:3
Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.
AID1386475Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID780283Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay2013Bioorganic & medicinal chemistry letters, Nov-15, Volume: 23, Issue:22
Inhibitory effect of oxygenated cholestan-3β-ol derivatives on the growth of Mycobacterium tuberculosis.
AID1386526Inhibition of beta-crystallin B2 V187E mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1608940Oral bioavailability in rat2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1386528Inhibition of gamma-crystallin C G129C mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1608937Clearance in iv dosed rat2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID695017Agonist activity at Hh receptor in mouse C3H10T1/2 cells assessed as fold increase in Gli1 expression at 5 uM by RT-PCR analysis relative to control2012ACS medicinal chemistry letters, Oct-11, Volume: 3, Issue:10
Structure-activity relationships for side chain oxysterol agonists of the hedgehog signaling pathway.
AID615677Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 20 hrs by luciferase reporter gene assay2011Journal of medicinal chemistry, Jul-14, Volume: 54, Issue:13
Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.
AID1386476Inhibition of alpha-crystallin A Y118D mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID83299Tested for its percent inhibition against HMG-CoA reductase transcription in HepG2 cells in HMG-CoA reductase assay1994Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.
AID1386480Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID768322Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as localization to endoplasmic reticulum and plasma membrane after 24 hrs by fluorescence microscopic analysis2013Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.
AID1656771Inhibition of SREBP (unknown origin) expressed in HEK293 cells assessed as reduction in LDLr promotor activity after 24 hrs by luciferase reporter assay2020Bioorganic & medicinal chemistry, 02-01, Volume: 28, Issue:3
Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.
AID1505268Agonist activity at 6xHis tagged human RORgammat LBD (262 to 507 residues) expressed in Escherichia coli BL21 (DE3) assessed as biotinylated SRC1-2 peptide coactivator recruitment by AlphaScreen assay2018Journal of medicinal chemistry, Jul-26, Volume: 61, Issue:14
Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Agonists as Potential Small Molecule Therapeutics for Cancer Immunotherapy.
AID101844Tested for its ability to activate Liver X receptor-alpha expressed as Relative efficacy determined by maximal increase in relative fluorescence in LiSA2001Journal of medicinal chemistry, Mar-15, Volume: 44, Issue:6
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
AID738362Stimulation of triglyceride biosynthesis in human HepG2 cells incubated at 2 uM for 14 hrs followed by sodium [14C]-acetate addition measured after 4 hrs2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID738364Reduction in cholesterol biosynthesis in human HepG2 cells incubated at 2 uM for 14 hrs followed by sodium [14C]-acetate addition measured after 4 hrs2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID738366Effect on triglyceride biosynthesis in human HepG2 cells at 30 uM2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID695018Agonist activity at LXR in mouse C3H10T1/2 cells assessed as fold increase in ABCA1 expression at 5 uM by RT-PCR analysis relative to control2012ACS medicinal chemistry letters, Oct-11, Volume: 3, Issue:10
Structure-activity relationships for side chain oxysterol agonists of the hedgehog signaling pathway.
AID1608923Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1608939Half life in rat2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1608936Stability in rat liver microsomes2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1386520Toxicity in human HLE-B3 cells transfected with peGFP-N1 assessed as reduction in cell viability of at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID83302Tested for the percent inhibition against HMG-CoA reductase transcription in HepG2 cells1994Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.
AID1608935Stability in human liver microsomes2019Journal of medicinal chemistry, 08-22, Volume: 62, Issue:16
Neuroactive Steroid
AID1632485Activity at 6His-tagged human RORgamma LBD (262 to 507 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of biotinylated SRC1 co-activator peptide recruitment by alphascreen assay2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Recent progress on nuclear receptor RORγ modulators.
AID83300Tested for its percent inhibition against HMG-CoA reductase transcription in HepG2 cells in HMG-CoA reductase m-RNA assay1994Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.
AID83301Tested for its percent inhibition against HMG-CoA reductase transcription in HepG2 cells in LDL-receptor binding assay1994Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.
AID1386519Toxicity in human HeLa cells transfected with peGFP-N1 assessed as reduction in cell viability of at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID1386527Inhibition of gamma-crystallin C G129C mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay2018Journal of medicinal chemistry, 10-11, Volume: 61, Issue:19
Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.
AID738368Effect on sterol biosynthesis in human HepG2 cells at 30 uM2013Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.
AID83295Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cells1994Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.
AID768321Binding affinity to NPC1 (unknown origin)2013Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.
AID504749qHTS profiling for inhibitors of Plasmodium falciparum proliferation2011Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
AID1802835Sterol-Binding Assay from Article 10.1074/jbc.M114.571216: \\Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.\\2014The Journal of biological chemistry, May-30, Volume: 289, Issue:22
Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.
AID1797959Cell-Free Ligand Sensing Assay (LiSA)-LXRalpha-SRC1 Assay from Article 10.1021/jm0004749: \\Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.\\2001Journal of medicinal chemistry, Mar-15, Volume: 44, Issue:6
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
AID1346769Human RAR-related orphan receptor-gamma (1F. Retinoic acid-related orphans)2010Molecular endocrinology (Baltimore, Md.), May, Volume: 24, Issue:5
Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma.
AID1346900Human GPR183 (Class A Orphans)2011Nature, Jul-27, Volume: 475, Issue:7357
Oxysterols direct B-cell migration through EBI2.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (839)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990179 (21.33)18.7374
1990's228 (27.18)18.2507
2000's170 (20.26)29.6817
2010's202 (24.08)24.3611
2020's60 (7.15)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (0.35%)5.53%
Reviews31 (3.63%)6.00%
Case Studies2 (0.23%)4.05%
Observational0 (0.00%)0.25%
Other817 (95.78%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
3 beta-hydroxy-delta 5-cholenic acid[no description available]medium30steroid
(20s)-20-hydroxycholesterol[no description available]high13020-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol		human metabolite;
mouse metabolite
24-hydroxycholesterol[no description available]medium3024-hydroxycholesterolbiomarker;
human blood serum metabolite;
mouse metabolite
27-hydroxycholesterol[no description available]medium37026-hydroxycholesterolapoptosis inducer;
human metabolite;
mouse metabolite;
neuroprotective agent
27-hydroxycholesterol[no description available]medium37326-hydroxycholesterolapoptosis inducer;
human metabolite;
mouse metabolite;
neuroprotective agent
(22r)-22-hydroxycholesterol[no description available]medium6022-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol
22s-hydroxycholesterol[no description available]medium5022-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol
24,25-epoxycholesterol[no description available]medium803beta-hydroxy-Delta(5)-steroid;
cholestanoid;
epoxy steroid		liver X receptor agonist
cholenic acid dimethylamide[no description available]medium30
itraconazole[no description available]medium10piperazines
veratramine[no description available]medium10piperidine alkaloid
jervine[no description available]medium10piperidines
gant58[no description available]medium10pyridines
gant 61[no description available]medium10aminal;
dialkylarylamine;
pyridines;
substituted aniline;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
glioma-associated oncogene inhibitor;
Hedgehog signaling pathway inhibitor
cyclopamine[no description available]medium10piperidinesglioma-associated oncogene inhibitor
purmorphamine[no description available]medium20aromatic ether;
morpholines;
purines;
secondary amino compound		osteogenesis regulator;
SMO receptor agonist
sag compound[no description available]medium10
gdc 0449[no description available]medium10benzamides;
monochlorobenzenes;
pyridines;
sulfone		antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist;
teratogenic agent
robotnikinin[no description available]medium10
physalin f[no description available]medium10enone;
epoxy steroid;
lactone;
physalin		antileishmanial agent;
antimalarial;
antineoplastic agent;
apoptosis inducer;
immunosuppressive agent
fatostatin[no description available]medium20thiazoles
warfarin[no description available]medium10benzenes;
hydroxycoumarin;
methyl ketone
cholest-5-en-3 beta,7 alpha-diol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
7alpha-hydroxy steroid;
oxysterol		mouse metabolite
cholest-5-en-3 beta,7 alpha-diol, (3beta,7beta)-isomer[no description available]medium407beta-hydroxy steroid;
oxysterol
dehydroepiandrosterone[no description available]medium9017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid		androgen;
human metabolite;
mouse metabolite
7-ketocholesterol[no description available]medium5803beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
7-oxo steroid;
cholestanoid		neuroprotective agent
cholestane-3,5,6-triol, (3beta, 5alpha, 6beta)-isomer[no description available]medium303beta-hydroxy steroid;
5alpha-hydroxy steroid;
6beta-hydroxy steroid
6-ketocholestanol[no description available]medium30
ezetimibe[no description available]medium10azetidines;
beta-lactam;
organofluorine compound		anticholesteremic drug;
antilipemic drug;
antimetabolite
19-hydroxycholesterol[no description available]medium40cholestanoid
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
diosgenin[no description available]medium103beta-sterol;
hexacyclic triterpenoid;
sapogenin;
spiroketal		antineoplastic agent;
antiviral agent;
apoptosis inducer;
metabolite
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
ciglitazone[no description available]medium10aromatic ether;
thiazolidinone		antineoplastic agent;
insulin-sensitizing drug
ciprofibrate[no description available]medium20cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
diclofenac[no description available]medium10amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
parthenolide[no description available]medium10germacranolide
quercetin[no description available]medium307-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
androstenediol[no description available]medium1017beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid		androgen;
human metabolite;
mouse metabolite;
radiation protective agent
ys 64[no description available]medium10cholestanoid
digoxin[no description available]medium10cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
sr 1078[no description available]medium10
zymosterol[no description available]medium103beta-sterol;
cholestanoid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
desmosterol[no description available]medium403beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C27-steroid;
cholestanoid		human metabolite;
mouse metabolite
lanosterol[no description available]medium8014alpha-methyl steroid;
3beta-sterol;
tetracyclic triterpenoid		bacterial metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
24,25-dihydrolanosterol[no description available]medium203beta-sterol;
tetracyclic triterpenoid		human metabolite;
mouse metabolite
bendazac lysine[no description available]medium10
osw 1[no description available]medium10
sk&f 99085[no description available]medium30
ketoconazole[no description available]medium10cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
tak 475[no description available]medium10
lovastatin[no description available]medium630delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
tirofiban[no description available]medium10L-tyrosine derivative;
piperidines;
sulfonamide		anticoagulant;
fibrin modulating drug;
platelet glycoprotein-IIb/IIIa receptor antagonist
eptifibatide[no description available]medium10homodetic cyclic peptide;
macrocycle;
organic disulfide		anticoagulant;
platelet aggregation inhibitor
mk-0429[no description available]medium10
dabigatran[no description available]medium10aromatic amide;
benzimidazoles;
beta-alanine derivative;
carboxamidine;
pyridines		anticoagulant;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
EC 3.4.21.5 (thrombin) inhibitor
rivaroxaban[no description available]medium10aromatic amide;
lactam;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
oxazolidinone;
thiophenes		anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
transforming growth factor beta[no description available]medium40
osteoprotegerin[no description available]medium10long-chain fatty acid
dapagliflozin[no description available]medium10aromatic ether;
C-glycosyl compound;
monochlorobenzenes		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
canagliflozin[no description available]medium10C-glycosyl compound;
organofluorine compound;
thiophenes		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
empagliflozin[no description available]medium10aromatic ether;
C-glycosyl compound;
monochlorobenzenes;
tetrahydrofuryl ether		hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
t0901317[no description available]medium100
1,2-dipalmitoylphosphatidylcholine[no description available]medium50
gw 3965[no description available]medium20diarylmethane
betadex[no description available]medium120cyclodextrin
sphingosine[no description available]medium30sphing-4-eninehuman metabolite;
mouse metabolite
n-acetylsphingosine[no description available]medium20N-acylsphingosine
adenosine[no description available]medium10adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
cgs 24012[no description available]medium10
24-hydroxycholesterol[no description available]medium16024-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol
glycolipids[no description available]medium110
adenine[no description available]medium206-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
3-methyladenine[no description available]medium10
phosphatidylinositol 4-phosphate[no description available]medium40
girard's reagent t[no description available]medium10
betaine[no description available]medium10amino-acid betaine;
glycine derivative		fundamental metabolite
3-hydroxy-3-methylglutaryl-coenzyme a[no description available]medium103-hydroxy-3-methylglutaryl-CoA;
3-hydroxy fatty acyl-CoA		human metabolite;
mouse metabolite
mevalonic acid[no description available]medium7203,5-dihydroxy-3-methylpentanoic acid
atorvastatin[no description available]medium52aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic)		environmental contaminant;
xenobiotic
deoxycholic acid[no description available]medium11bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
resveratrol[no description available]medium11resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
1-palmitoyl-2-oleoylphosphatidylcholine[no description available]medium40
phosphatidylcholines[no description available]medium1701,2-diacyl-sn-glycero-3-phosphocholine
gemfibrozil[no description available]medium30aromatic etherantilipemic drug
pregnenolone[no description available]medium53020-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid		human metabolite;
mouse metabolite
carbamazepine[no description available]medium10dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
11-ketotestosterone[no description available]medium2011-oxo steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
human metabolite;
marine xenobiotic metabolite
cholest-5-ene-3,4-diol[no description available]medium60
1,2-oleoylphosphatidylcholine[no description available]medium50phosphatidylcholine(1+)
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
pf-429242[no description available]medium10
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
itraconazole[no description available]medium10aromatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles		EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor
ergosterol[no description available]medium303beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
stigmasterol[no description available]medium203beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
phytosterols;
stigmastane sterol		plant metabolite
interleukin-8[no description available]medium160
angiotensin ii[no description available]medium60amino acid zwitterion;
angiotensin II		human metabolite
ribavirin[no description available]medium101-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
cholecalciferol[no description available]medium20D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone		geroprotector;
human metabolite
oligonucleotides[no description available]medium10
ly 295427[no description available]medium80
dizocilpine maleate[no description available]medium10maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
simvastatin[no description available]medium80delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug
nad[no description available]medium10organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
tryptophan[no description available]medium10erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
7,25-dihydroxycholesterol[no description available]medium30
sr 12813[no description available]medium20organic phosphonate;
phenols		pregnane X receptor agonist
tert-butylhydroperoxide[no description available]medium10alkyl hydroperoxideantibacterial agent;
oxidising agent
n-hydroxyphthalimide[no description available]medium10
5,6-epoxycholesterol[no description available]medium10
lysophosphatidylcholines[no description available]medium501-O-acyl-sn-glycero-3-phosphocholine
acetovanillone[no description available]medium10acetophenones;
aromatic ketone;
methyl ketone		antirheumatic drug;
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
cytochrome c-t[no description available]medium30
cholesterol hydroperoxide[no description available]medium10
schweinfurthin b[no description available]medium10
stilbenes[no description available]medium20stilbene
muramidase[no description available]medium10
calcitriol[no description available]medium10D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
involucrin[no description available]medium30
triiodothyronine[no description available]medium202-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
gefitinib[no description available]medium10aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
betulin[no description available]medium10diol;
pentacyclic triterpenoid		analgesic;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
metabolite
thiazoles[no description available]medium101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
quinazolines[no description available]medium20azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione[no description available]medium10benzenes;
thiadiazolidine		anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
interleukin-1beta (163-171)[no description available]medium10
pyrazolanthrone[no description available]medium10anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
lathosterol[no description available]medium103beta-sterol;
C27-steroid;
cholestanoid;
Delta(7)-sterol		human metabolite;
mouse metabolite
mdl 201053[no description available]medium10
22-hydroxycholesterol[no description available]medium200cholanoid
4-chloro-7-nitrobenzofurazan[no description available]medium10benzoxadiazole;
C-nitro compound;
organochlorine compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome
3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate[no description available]medium101,1-diunsubstituted alkanesulfonate
u 0126[no description available]medium10aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
aminoglutethimide[no description available]medium120dicarboximide;
piperidones;
substituted aniline		adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
androstenedione[no description available]medium14017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
8-epi-prostaglandin f2alpha[no description available]medium10F2-isoprostanebiomarker;
bronchoconstrictor agent;
vasoconstrictor agent
dinoprost[no description available]medium40monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
leupeptins[no description available]medium60
benzyloxycarbonylleucyl-leucyl-leucine aldehyde[no description available]medium30amino aldehyde;
carbamate ester;
tripeptide		proteasome inhibitor
activins[no description available]medium10
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
desoxycorticosterone[no description available]medium4020-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
corticosterone[no description available]medium12011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
colforsin[no description available]medium170acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
rutecarpine[no description available]medium10beta-carbolines
evodiamine[no description available]medium10beta-carbolines
8-bromo cyclic adenosine monophosphate[no description available]medium2703',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
phytosterols[no description available]medium10
cytellin[no description available]medium10
tretinoin[no description available]medium90retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
alitretinoin[no description available]medium70retinoic acidantineoplastic agent;
keratolytic drug;
metabolite;
retinoid X receptor agonist
farnesol[no description available]medium20farnesolplant metabolite
mevalonolactone[no description available]medium1204-hydroxy-4-methyloxan-2-onefungal metabolite;
plant metabolite
lycopene[no description available]medium10acyclic caroteneantioxidant;
plant metabolite
beta-glycerophosphoric acid[no description available]medium10glycerol monophosphateEscherichia coli metabolite;
plant metabolite
genistein[no description available]medium207-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
6-ketoprostaglandin f1 alpha[no description available]medium10prostaglandins Falphahuman metabolite;
mouse metabolite
pregnenolone carbonitrile[no description available]medium10aliphatic nitrile
troleandomycin[no description available]medium10acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic
beta-escin[no description available]medium20
schweinfurthin a[no description available]medium10
ritterazine b[no description available]medium10
cephalostatin i[no description available]medium10
triptolide[no description available]medium10diterpenoid;
epoxide;
gamma-lactam;
organic heteroheptacyclic compound		antispermatogenic agent;
plant metabolite
phenanthrenes[no description available]medium10
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
serine[no description available]medium30L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
1-anilino-8-naphthalenesulfonate[no description available]medium10aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
quinacrine[no description available]medium10acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
u 18666a[no description available]medium70hydrochlorideantiviral agent;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
Hedgehog signaling pathway inhibitor;
nicotinic antagonist;
sterol biosynthesis inhibitor
trilostane[no description available]medium5017beta-hydroxy steroid;
3-hydroxy steroid;
androstanoid;
epoxy steroid;
nitrile		abortifacient;
antineoplastic agent;
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor
dihydrotestosterone[no description available]medium7017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
propylthiouracil[no description available]medium20pyrimidinethioneantidote to paracetamol poisoning;
antimetabolite;
antioxidant;
antithyroid drug;
carcinogenic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
hormone antagonist
dactinomycin[no description available]medium80actinomycinmutagen
guanosine 5'-o-(3-thiotriphosphate)[no description available]medium10nucleoside triphosphate analogue
oxazolone[no description available]medium10
tetradecanoylphorbol acetate[no description available]medium90acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
pirinixic acid[no description available]medium20aryl sulfide;
organochlorine compound;
pyrimidines
bezafibrate[no description available]medium20aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
prostaglandin d2[no description available]medium40prostaglandins Dhuman metabolite;
mouse metabolite
9-deoxy-delta-9-prostaglandin d2[no description available]medium10prostaglandins Jhuman metabolite
aldosterone[no description available]medium6011beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
filipin[no description available]medium30
fibrinogen[no description available]medium10iditolfungal metabolite
d-alpha tocopherol[no description available]medium80alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
oligomycins[no description available]medium10
1-methyl-3-isobutylxanthine[no description available]medium1003-isobutyl-1-methylxanthine
diphenylhexatriene[no description available]medium20alkatrienefluorochrome
ketoconazole[no description available]medium70dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
clofibrate[no description available]medium20aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
pd 98059[no description available]medium10aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
lignans[no description available]medium10
pyrroles[no description available]medium30pyrrole;
secondary amine
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium10isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
magnolol[no description available]medium10biphenyls
oleic acid[no description available]medium170octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
kt 5720[no description available]medium10carboxylic ester;
gamma-lactam;
hemiaminal;
indolocarbazole;
organic heterooctacyclic compound;
semisynthetic derivative;
tertiary alcohol		EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
kn 93[no description available]medium10monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector
ucn 1028 c[no description available]medium10
kn 62[no description available]medium10piperazines
mevastatin[no description available]medium1602-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite
pitavastatin[no description available]medium10cyclopropanes;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
quinolines;
statin (synthetic)		antioxidant
cerivastatin[no description available]medium10dihydroxy monocarboxylic acid;
pyridines;
statin (synthetic)
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine;
aldehyde		apoptosis inducer
taurocholic acid[no description available]medium10amino sulfonic acid;
bile acid taurine conjugate		human metabolite
tocotrienols[no description available]medium10diterpenoid
cholestanol[no description available]medium20cholestanoid
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
fenofibric acid[no description available]medium10aromatic ketone;
chlorobenzophenone;
monocarboxylic acid		drug metabolite;
marine xenobiotic metabolite
troglitazone[no description available]medium10chromanes;
thiazolidinone		anticoagulant;
anticonvulsant;
antineoplastic agent;
antioxidant;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
hypoglycemic agent;
platelet aggregation inhibitor;
vasodilator agent
fenofibrate[no description available]medium10aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
pioglitazone[no description available]medium10aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic
cholest-5-ene-3 beta,26-diol[no description available]high5026-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol		EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
eicosapentaenoic acid[no description available]medium20icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical
arachidonic acid[no description available]medium60icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
acetyl-aspartyl-glutamyl-valyl-aspartal[no description available]medium40tetrapeptideprotease inhibitor
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
cholesterol alpha-oxide[no description available]medium803beta-hydroxy steroid;
epoxy steroid;
oxysterol
cholestane-3,5,6-triol[no description available]medium160
farnesyl pyrophosphate[no description available]medium10farnesyl diphosphateEscherichia coli metabolite;
mouse metabolite
geranyl pyrophosphate[no description available]medium10polyprenyl diphosphateEscherichia coli metabolite;
mouse metabolite
sesquiterpenes[no description available]medium20
sb 203580[no description available]medium10imidazoles;
monofluorobenzenes;
pyridines;
sulfoxide		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent
acetone[no description available]medium10ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
phenyl acetate[no description available]medium190benzenes;
phenyl acetates
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
squalestatin 1[no description available]medium40acetate ester;
cyclic ketal;
oxabicycloalkane;
polyketide;
tertiary alcohol;
tricarboxylic acid		EC 2.5.1.21 (squalene synthase) inhibitor;
fungal metabolite
15-deoxyprostaglandin j2[no description available]medium10
hydroxyl radical[no description available]medium10oxygen hydride;
oxygen radical;
reactive oxygen species
diacetyldichlorofluorescein[no description available]medium10
erythrosine[no description available]medium20
cadmium chloride[no description available]medium10cadmium coordination entity
bucladesine[no description available]medium1303',5'-cyclic purine nucleotide
nifedipine[no description available]medium20C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
verapamil[no description available]medium30aromatic ether;
nitrile;
polyether;
tertiary amino compound
androst-16-en-3-one[no description available]medium103-oxo steroid;
androstanoid		mammalian metabolite;
pheromone
digitonin[no description available]medium20
bromochloroacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound
tsushimycin[no description available]medium10
showdomycin[no description available]medium10
1-deoxynojirimycin[no description available]medium102-(hydroxymethyl)piperidine-3,4,5-triol;
piperidine alkaloid		anti-HIV agent;
anti-obesity agent;
bacterial metabolite;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
hypoglycemic agent;
plant metabolite
acetylglucosamine[no description available]medium10N-acetyl-D-glucosamineepitope
mannose[no description available]medium10D-aldohexose;
D-mannose;
mannopyranose		metabolite
castanospermine[no description available]medium10indolizidine alkaloidanti-HIV-1 agent;
anti-inflammatory agent;
EC 3.2.1.* (glycosidase) inhibitor;
metabolite
glucosamine[no description available]medium30D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
swainsonine[no description available]medium10indolizidine alkaloidantineoplastic agent;
EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor;
immunological adjuvant;
plant metabolite
asparagine[no description available]medium20amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
uracil[no description available]medium10pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
inositol[no description available]medium20cyclitol;
hexol
streptovirudin[no description available]medium10
dolichol monophosphate[no description available]medium10
6-bromoconduritol[no description available]medium10
2-methylpentane[no description available]medium10alkane
cycloheximide[no description available]medium280antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
cyanoketone[no description available]medium30
22-ketocholesterol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid		EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) inhibitor
tempo[no description available]medium10aminoxyls;
piperidines		catalyst;
ferroptosis inhibitor;
radical scavenger
5-doxylstearate[no description available]medium10aminoxyls
chloroquine[no description available]medium40aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
thymidine[no description available]medium70pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
cytochalasin d[no description available]medium20
cytochalasin b[no description available]medium30cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor
octanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite
caprylates[no description available]medium10fatty acid anion 8:0;
straight-chain saturated fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
concanavalin a[no description available]medium60
strontium[no description available]medium10alkaline earth metal atom
barium[no description available]medium10alkaline earth metal atom;
elemental barium
manganese[no description available]medium10elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
arsenazo iii[no description available]medium10
sodium molybdate(vi)[no description available]medium10inorganic sodium saltpoison
molybdenum[no description available]medium10chromium group element atommicronutrient
dimyristoylphosphatidylcholine[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
chenodeoxycholic acid[no description available]medium40bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
cholesteryl sulfate[no description available]medium60steroid sulfatehuman metabolite
pregnenolone sulfate[no description available]medium10steroid sulfateEC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite
puromycin[no description available]medium30puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
emetine[no description available]medium20isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
cholestyramine resin[no description available]medium20
rubidium[no description available]medium10alkali metal atom
5,22-cholestadien-3beta-ol[no description available]medium10cholestanoid
20,22-dihydroxycholesterol[no description available]high1020-hydroxy steroid;
22-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
oxysterol		human metabolite;
mouse metabolite
palmitic acid[no description available]medium30long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite
monensin[no description available]medium30cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
aloxistatin[no description available]medium10epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide		anticoronaviral agent;
cathepsin B inhibitor
acetylleucyl-leucyl-norleucinal[no description available]medium40aldehyde;
tripeptide		cysteine protease inhibitor
leucine[no description available]medium30amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
safingol[no description available]medium10amino alcohol
choline[no description available]medium20cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
brefeldin a[no description available]medium40macrolide antibioticPenicillium metabolite
cyclopentane[no description available]medium40cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
masoprocol[no description available]medium10nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite
6-ketocholestanol[no description available]medium10cholestanoid
deuterium[no description available]medium10dihydrogen
cholic acid[no description available]medium1012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
fluorine[no description available]medium10diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
phosphorylcholine[no description available]medium10phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
proadifen[no description available]medium10diarylmethane
n,n'-diphenyl-4-phenylenediamine[no description available]medium10N-substituted diamine;
secondary amino compound		antioxidant
mannitol[no description available]medium10mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
g(m3) ganglioside[no description available]medium10alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide;
sialodiosylceramide;
sialotriaosylceramide		mouse metabolite
bromocriptine[no description available]medium20indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist
osmium[no description available]medium10iron group element atom;
platinum group metal atom
cholesteryl succinate[no description available]medium30cholestane ester;
dicarboxylic acid monoester;
hemisuccinate		detergent
epidermal growth factor[no description available]medium20
3,3'-dioctadecylindocarbocyanine[no description available]medium10Cy5 dye;
indolium ion		fluorochrome
carbocyanines[no description available]medium10cyanine dye;
organic iodide salt		fluorochrome
acetic acid[no description available]medium30monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
plastochromanol 8[no description available]medium10
cholest-8(14)-en-3-ol-15-one[no description available]medium1015-oxo steroid;
3beta-hydroxy steroid
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]medium10(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
phenobarbital[no description available]medium20barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
clofibric acid[no description available]medium10aromatic ether;
monocarboxylic acid;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist
beta-naphthoflavone[no description available]medium10extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound		aryl hydrocarbon receptor agonist
cafestol[no description available]medium20diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
plant metabolite
ouabain[no description available]medium2011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
thromboplastin[no description available]medium10
sk&f 104976[no description available]medium10
cysteine[no description available]medium10cysteiniumfundamental metabolite
cl 277082[no description available]medium20
ethylene dimethanesulfonate[no description available]medium10
lactacystin[no description available]medium10lactam;
S-substituted L-cysteine
acetylcysteine[no description available]medium10acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
16-fluoro-5-androsten-17-one[no description available]medium10
sodium fluoride[no description available]medium10fluoride saltmutagen
san 58035[no description available]medium30
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4,4,10-trimethyl-trans-decal-3-ol[no description available]medium20
2-naphthol[no description available]medium20naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
squalene[no description available]medium20triterpenehuman metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
metyrapone[no description available]medium10aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
3-hydroxy-5-cholestenoic acid[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
monocarboxylic acid;
steroid acid		bacterial metabolite
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone[no description available]medium10
fura-2[no description available]medium20
metallothionein[no description available]medium10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine[no description available]medium102-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
potassium chloride[no description available]medium20inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
aurintricarboxylic acid[no description available]medium20monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist
ascorbic acid[no description available]medium20ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
staurosporine[no description available]medium20ammonium ion derivative
okadaic acid[no description available]medium10ketal
cp 113818[no description available]medium10
kahweol[no description available]medium10diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite
limonene[no description available]medium10cycloalkene;
p-menthadiene		human metabolite
1-butanol[no description available]medium10alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
cholest-4-en-3-one[no description available]medium103-oxo-Delta(4) steroid;
cholestanoid		human metabolite;
plant metabolite
neopterin[no description available]medium10
2-hexadecynoic acid[no description available]medium10long-chain fatty acid
ethylnitrosourea[no description available]medium10N-nitrosoureasalkylating agent;
carcinogenic agent;
genotoxin;
mutagen
tripalmitin[no description available]medium10triglyceride
tamoxifen[no description available]medium10stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
fulvestrant[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid;
organofluorine compound;
sulfoxide		antineoplastic agent;
estrogen antagonist;
estrogen receptor antagonist
calcimycin[no description available]medium60benzoxazole
levonorgestrel[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound		contraceptive drug;
female contraceptive drug;
progestin;
synthetic oral contraceptive
miconazole[no description available]medium20dichlorobenzene;
ether;
imidazoles
econazole[no description available]medium10dichlorobenzene;
ether;
imidazoles;
monochlorobenzenes
2,2'-(hydroxynitrosohydrazono)bis-ethanamine[no description available]medium10
cyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
oxadiazoles[no description available]medium10
quinoxalines[no description available]medium10mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one[no description available]medium10oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor
ym17e[no description available]medium10
15-deoxy-delta(12,14)-prostaglandin j2[no description available]medium10prostaglandins Jelectrophilic reagent;
insulin-sensitizing drug;
metabolite
13-hydroxy-9,11-octadecadienoic acid[no description available]medium10octadecadienoic acid
9-hydroxy-10,12-octadecadienoic acid[no description available]medium10HODE;
octadecadienoic acid		human metabolite;
metabolite;
mouse metabolite;
plant metabolite
15-hydroxy-5,8,11,13-eicosatetraenoic acid[no description available]medium10
11-hydroxy-5,8,12,14-eicosatetraenoic acid[no description available]medium10
cholesterol 7-hydroperoxide[no description available]medium10
calpain[no description available]medium10
myricetin[no description available]medium107-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite
rutin[no description available]medium10disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
calpain inhibitor 2[no description available]medium10peptide
arachidonyltrifluoromethane[no description available]medium10fatty acid derivative;
ketone;
olefinic compound;
organofluorine compound		EC 3.1.1.4 (phospholipase A2) inhibitor
indomethacin[no description available]medium20aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
acetyl coenzyme a[no description available]medium10acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
catechin[no description available]medium10catechinantioxidant;
plant metabolite
epigallocatechin gallate[no description available]medium10flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite
indo-1[no description available]medium10indolesfluorochrome
sq-23377[no description available]medium30cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite
2,5-di-tert-butylhydroquinone[no description available]medium10hydroquinones
thapsigargin[no description available]medium10butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
orotic acid[no description available]medium10pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
nandrolone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid		human metabolite
androstane-3,17-diol[no description available]medium1017-hydroxy steroid;
3-hydroxy steroid;
androstanoid
amphotericin b[no description available]medium20antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
thiophenes[no description available]medium10mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
simvastatin acid[no description available]medium10carbonyl compound
nb 598[no description available]medium10
azastene[no description available]medium10
colchicine[no description available]medium10alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
merocyanine dye[no description available]medium10
pyrimidinones[no description available]medium10
7-dehydrocholesterol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
Delta(5),Delta(7)-sterol		human metabolite;
mouse metabolite
mifepristone[no description available]medium103-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive
gossypolone[no description available]medium10
gossypol[no description available]medium30
20-alpha-dihydroprogesterone[no description available]medium5020-hydroxypregn-4-en-3-onehuman metabolite;
mouse metabolite
17-alpha-hydroxyprogesterone[no description available]medium2017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin
aphidicolin[no description available]medium10tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite
chondroitin sulfates[no description available]medium10
cosyntropin[no description available]medium10
methionine[no description available]medium30aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
ammonium sulfate[no description available]medium10ammonium salt;
inorganic sulfate salt		fertilizer
phentolamine[no description available]medium10imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
propranolol[no description available]medium10naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
1,2-dioctanoylglycerol[no description available]medium10
imipramine[no description available]medium10dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
w 7[no description available]medium10
p-methoxy-n-methylphenethylamine[no description available]medium10aromatic ether;
secondary amino compound		metabolite
trifluoperazine[no description available]medium20N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines		antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug
6-carboxyfluorescein[no description available]medium10monocarboxylic acid
1,2-dielaidoylphosphatidylethanolamine[no description available]medium10
4-carboxyfluorescein[no description available]medium10monocarboxylic acidfluorochrome
myelin basic protein[no description available]medium10
dinoprostone[no description available]medium30prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
kaur-16-en-15-ol[no description available]medium10
dolichols[no description available]medium40polyterpene
azides[no description available]medium10pseudohalide anionmitochondrial respiratory-chain inhibitor
8-azidoadenosine-3',5'-monophosphate[no description available]medium10
fluorides[no description available]medium10halide anion;
monoatomic fluorine
ammonium chloride[no description available]medium10ammonium salt;
inorganic chloride		ferroptosis inhibitor
3,3'-iminodipropionitrile[no description available]medium10
deoxyglucose[no description available]medium10
retinol[no description available]medium20retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
ubiquinone[no description available]medium30
lhrh, ala(6)-[no description available]medium10
prostaglandin a2[no description available]medium10prostaglandins Ahuman metabolite
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]medium10
linoleic acid[no description available]medium20octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
acid phosphatase[no description available]medium10
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
lasalocid[no description available]medium10beta-hydroxy ketone;
monocarboxylic acid;
monohydroxybenzoic acid;
oxanes;
oxolanes;
polyether antibiotic;
secondary alcohol;
tertiary alcohol		bacterial metabolite;
coccidiostat;
ionophore
pimozide[no description available]medium10benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
diltiazem[no description available]medium105-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetateantihypertensive agent;
calcium channel blocker;
vasodilator agent
piperidines[no description available]medium10
raloxifene hydrochloride[no description available]medium10hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
acetylcarnitine[no description available]low00O-acylcarnitinehuman metabolite
2-oxo-3-methylvalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite
alpha-ketoisovalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		human metabolite;
Saccharomyces cerevisiae metabolite
2,3-diphosphoglycerate[no description available]low00bisphosphoglyceric acid;
tetronic acid derivative		human metabolite
2-keto-4-methylvalerate[no description available]low002-oxo monocarboxylic acid;
branched-chain keto acid		algal metabolite;
human metabolite
3-hydroxyanthranilic acid[no description available]low00aminobenzoic acid;
monohydroxybenzoic acid		human metabolite;
mouse metabolite
3-hydroxykynurenine[no description available]low00hydroxykynureninehuman metabolite
3-oxoadipic acid[no description available]low00dicarboxylic fatty acid;
oxo dicarboxylic acid		bacterial xenobiotic metabolite;
human metabolite
3-mercaptopyruvic acid[no description available]low002-oxo monocarboxylic acid;
thiol		antidote to cyanide poisoning;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
phosphoserine[no description available]low00non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative		human metabolite
3-phenylpropionic acid[no description available]low00benzenes;
monocarboxylic acid		antifungal agent;
human metabolite;
plant metabolite
gamma-aminobutyric acid[no description available]low00amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
4-hydroxyphenylacetic acid[no description available]low00monocarboxylic acid;
phenols		fungal metabolite;
human metabolite;
mouse metabolite;
plant metabolite
isocaproaldehyde[no description available]low00alpha-CH2-containing aldehydehuman metabolite;
mouse metabolite
aminolevulinic acid[no description available]low004-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid		antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
5-aminovaleric acid[no description available]low00amino acid zwitterion;
delta-amino acid;
omega-amino fatty acid		human metabolite
5-hydroxytryptophan[no description available]low00hydroxytryptophanhuman metabolite;
neurotransmitter
acetaldehyde[no description available]low00aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
acetyl phosphate[no description available]low00acyl monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
allantoin[no description available]low00imidazolidine-2,4-dione;
ureas		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary
anthranilic acid[no description available]low00aminobenzoic acidhuman metabolite;
mouse metabolite
beta-alanine[no description available]low00amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
betaine aldehyde[no description available]low00quaternary ammonium ionAspergillus metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
ureidosuccinic acid[no description available]low00aspartic acid derivative;
C4-dicarboxylic acid;
N-carbamoyl-amino acid		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
carbon monoxide[no description available]low00carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
carnitine[no description available]low00amino-acid betainehuman metabolite;
mouse metabolite
chlorine[no description available]low00halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
coumarin[no description available]low00coumarinsfluorescent dye;
human metabolite;
plant metabolite
aminoethylphosphonic acid[no description available]low00phosphonic acids;
primary amino compound;
zwitterion		human metabolite;
metabolite;
mouse metabolite
dihydrolipoic acid[no description available]low00thio-fatty acidantioxidant;
human metabolite;
neuroprotective agent
trimethylenediamine[no description available]low00alkane-alpha,omega-diaminehuman metabolite;
mouse metabolite;
reagent
3-hydroxybutyric acid[no description available]low00(omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid		human metabolite
methylmalonic acid[no description available]low00C4-dicarboxylic acidhuman metabolite
pyrrolidonecarboxylic acid[no description available]low00oxoproline;
pyrrolidin-2-ones;
pyrrolidinemonocarboxylic acid		human metabolite
3,4-dihydroxyphenylacetic acid[no description available]low00catechols;
dihydroxyphenylacetic acid		human metabolite
alpha-keto-delta-guanidinovaleric acid[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
creatine[no description available]low00glycine derivative;
guanidines;
zwitterion		geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical
cytosine[no description available]low00aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydrouracil[no description available]low00pyrimidoneEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
dihydrolipoamide[no description available]low00dithiol;
monocarboxylic acid amide		cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone phosphate[no description available]low00glycerone phosphates;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone[no description available]low00ketotriose;
primary alpha-hydroxy ketone		antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dimethylglycine[no description available]low00amino acid zwitterion;
N-methyl-amino acid;
N-methylglycines		Daphnia magna metabolite;
human metabolite;
mouse metabolite
5,6-dimethylbenzimidazole[no description available]low00dimethylbenzimidazoleEscherichia coli metabolite;
human metabolite
ethanolamine[no description available]low00ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
gamma-butyrobetaine[no description available]low00amino-acid betaineEscherichia coli metabolite;
human metabolite
glutaric acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		Daphnia magna metabolite;
human metabolite
alpha-glycerophosphoric acid[no description available]low00glycerol monophosphatealgal metabolite;
human metabolite
glycolaldehyde[no description available]low00glycolaldehydesfundamental metabolite;
human metabolite
glyoxylic acid[no description available]low002-oxo monocarboxylic acid;
aldehydic acid		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
glycocyamine[no description available]low00guanidinoacetic acids;
zwitterion		bacterial metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
hydrogen cyanide[no description available]low00hydracid;
one-carbon compound		Escherichia coli metabolite;
human metabolite;
poison
hydrogen carbonate[no description available]low00carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
histamine[no description available]low00aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
homogentisic acid[no description available]low00dihydroxyphenylacetic acid;
hydroquinones		human metabolite;
plant metabolite
indole-3-acetaldehyde[no description available]low00indoleacetaldehydebacterial metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
indoleacetic acid[no description available]low00indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
itaconic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid;
olefinic compound		fungal metabolite;
human metabolite
potassium[no description available]low00alkali metal cation;
elemental potassium;
monoatomic monocation;
monovalent inorganic cation		cofactor;
human metabolite
dihydroxyphenylalanine[no description available]low00hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative		human metabolite
kynurenine[no description available]low00aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
lipoamide[no description available]low00dithiolanes;
monocarboxylic acid amide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
malonic acid[no description available]low00alpha,omega-dicarboxylic acidhuman metabolite
methylmercaptan[no description available]low00alkanethiolhuman metabolite;
Saccharomyces cerevisiae metabolite
pyruvaldehyde[no description available]low002-oxo aldehyde;
propanals		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
methanol[no description available]low00alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
melatonin[no description available]low00acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
n-acetylserotonin[no description available]low00acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist
n-methylphenylethanolamine[no description available]low00alkaloid;
phenylethanolamines		human metabolite;
plant metabolite
n'-acetylspermine[no description available]low00acetamides;
acetylspermine		human metabolite
nitrites[no description available]low00monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
hydroxypyruvic acid[no description available]low002-oxo monocarboxylic acid;
3-hydroxy monocarboxylic acid;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite
oxalic acid[no description available]low00alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
4-hydroxyphenylpyruvic acid[no description available]low002-oxo monocarboxylic acid;
phenols		human metabolite
hexadecanal[no description available]low002,3-saturated fatty aldehyde;
long-chain fatty aldehyde		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetic acid[no description available]low00benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
2-hydroxyphenethylamine[no description available]low00phenylethanolamineshuman metabolite
phenethylamine[no description available]low00alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
phosphoric acid[no description available]low00phosphoric acidsalgal metabolite;
fertilizer;
human metabolite;
NMR chemical shift reference compound;
solvent
phosphorylethanolamine[no description available]low00phosphoethanolamine;
primary amino compound		algal metabolite;
human metabolite;
mouse metabolite
picolinic acid[no description available]low00pyridinemonocarboxylic acidhuman metabolite;
MALDI matrix material
pyridoxal[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxal phosphate[no description available]low00methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine[no description available]low00aminoalkylpyridine;
hydroxymethylpyridine;
monohydroxypyridine;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine phosphate[no description available]low00aminoalkylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxine[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
quinolinic acid[no description available]low00pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
thiosulfates[no description available]low00divalent inorganic anion;
sulfur oxide;
sulfur oxoanion		human metabolite
sarcosine[no description available]low00N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines		Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite
taurine[no description available]low00amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
thiamine[no description available]low00primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thymine[no description available]low00pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-(4-methyl-1,3-thiazol-5-yl)ethanol[no description available]low001,3-thiazoles;
primary alcohol		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
tryptamine[no description available]low00aminoalkylindole;
aralkylamino compound;
indole alkaloid;
tryptamines		human metabolite;
mouse metabolite;
plant metabolite
uric acid[no description available]low00uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
urea[no description available]low00isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
vanilmandelic acid[no description available]low002-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite
perillic acid[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid		antineoplastic agent;
human metabolite;
mouse metabolite
meglutol[no description available]low003-hydroxy carboxylic acid;
dicarboxylic acid;
tertiary alcohol		anticholesteremic drug;
antimetabolite;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
human metabolite;
plant metabolite
homovanillic acid[no description available]low00guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite
3-hydroxy-4-methoxyphenethylamine[no description available]low00monomethoxybenzene;
phenols;
phenylethylamine;
primary amino compound		human metabolite;
rat metabolite
hydroxyindoleacetic acid[no description available]low00indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
5-methoxytryptamine[no description available]low00aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist
cetyl alcohol[no description available]low00hexadecanol;
long-chain primary fatty alcohol		algal metabolite;
flavouring agent;
human metabolite;
plant metabolite
4-cresol[no description available]low00cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
debrisoquin[no description available]low00carboxamidine;
isoquinolines		adrenergic agent;
antihypertensive agent;
human metabolite;
sympatholytic agent
decanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
anti-inflammatory agent;
antibacterial agent;
human metabolite;
plant metabolite;
volatile oil component
nordazepam[no description available]low001,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative
2,5-dihydroxybenzoic acid[no description available]low00dihydroxybenzoic acidEC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
fungal metabolite;
human metabolite;
MALDI matrix material;
mouse metabolite
tele-methylhistamine[no description available]low00imidazoles;
primary amino compound		human metabolite;
mouse metabolite
indolepropionic acid[no description available]low00indol-3-yl carboxylic acidauxin;
human metabolite;
plant metabolite
kynurenic acid[no description available]low00monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
3-phenyllactic acid[no description available]low002-hydroxy monocarboxylic acidhuman metabolite
2-amino-3-phosphonopropionic acid[no description available]low00alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist
2-phenylglycine[no description available]low00non-proteinogenic alpha-amino acidhuman metabolite
oxidopamine[no description available]low00benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
sebacic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite;
plant metabolite
stearic acid[no description available]low00long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
succinylacetone[no description available]low00beta-diketone;
dioxo monocarboxylic acid		human metabolite
tolbutamide[no description available]low00N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
retinoic acid[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
retinoid		human metabolite
tyramine[no description available]low00monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
estriol[no description available]low0016alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid		estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite
sorbitol[no description available]low00glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
hydroxyproline[no description available]low004-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
cysteine[no description available]low00cysteine zwitterion;
cysteine;
L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
flour treatment agent;
human metabolite
estrone[no description available]low0017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
androsterone[no description available]low0017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
etiocholanolone[no description available]low0017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid		human metabolite;
mouse metabolite
isonicotinic acid[no description available]low00pyridinemonocarboxylic acidalgal metabolite;
human metabolite
glutamine[no description available]low00amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
sucrose[no description available]low00glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
adenosine diphosphate[no description available]low00adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
uridine[no description available]low00uridinesdrug metabolite;
fundamental metabolite;
human metabolite
uridine monophosphate[no description available]low00pyrimidine ribonucleoside 5'-monophosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
levodopa[no description available]low00amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
cysteamine[no description available]low00amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
cytidine monophosphate[no description available]low00cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
cytidine[no description available]low00cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
histidine[no description available]low00amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
n-pentanol[no description available]low00pentanol;
short-chain primary fatty alcohol		human metabolite;
plant metabolite
valine[no description available]low00L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
threonine[no description available]low00amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
isoleucine[no description available]low00aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ethylamine[no description available]low00primary aliphatic aminehuman metabolite
skatole[no description available]low00methylindolehuman metabolite;
mammalian metabolite
quinaldic acid[no description available]low00quinolinemonocarboxylic acidhuman metabolite;
Saccharomyces cerevisiae metabolite
3-methylpentane[no description available]low00alkane;
volatile organic compound		allelochemical;
human metabolite;
non-polar solvent
methylcyclopentane[no description available]low00cycloalkane;
volatile organic compound		human metabolite;
plant metabolite
phosphoribosyl pyrophosphate[no description available]low005-O-phosphono-D-ribofuranosyl diphosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
1-phenethylamine[no description available]low00phenylethylaminehuman metabolite
trehalose[no description available]low00trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
isethionic acid[no description available]low00alkanesulfonic acidhuman metabolite
methylcyclohexane[no description available]low00cycloalkane;
volatile organic compound		aprotic solvent;
human metabolite;
plant metabolite
piperidine[no description available]low00azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine		base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent
undecanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		antifungal agent;
human metabolite
1-tridecanol[no description available]low00long-chain primary fatty alcohol;
tridecanol		bacterial metabolite;
human metabolite;
plant metabolite
stearyl alcohol[no description available]low00long-chain primary fatty alcohol;
octadecanol		algal metabolite;
human metabolite;
plant metabolite
acetol[no description available]low00methyl ketone;
primary alcohol;
primary alpha-hydroxy ketone;
propanones		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-methylbutanoic acid[no description available]low00methylbutyric acidbacterial metabolite;
human metabolite
hexanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		human metabolite;
plant metabolite
isopropyl palmitate[no description available]low00fatty acid ester;
isopropyl ester		human metabolite
homoarginine[no description available]low00homoarginine;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid		biomarker;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
human metabolite;
rat metabolite;
xenobiotic metabolite
dibenzo(a,l)pyrene[no description available]low00ortho- and peri-fused polycyclic arenehuman metabolite;
mutagen
diiodotyrosine[no description available]low00diiodotyrosine;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite
3-methoxytyrosine[no description available]low00aromatic L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monomethoxybenzene;
non-proteinogenic L-alpha-amino acid		human metabolite
thiocyanate[no description available]low00pseudohalide anion;
sulfur molecular entity		human metabolite
4-hydroxyphenyllactic acid[no description available]low002-hydroxy carboxylic acid;
phenols		bacterial metabolite;
human metabolite
citrulline[no description available]low00amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
lithocholic acid[no description available]low00bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite
4-methylcatechol[no description available]low00methylcatecholantioxidant;
carcinogenic agent;
hapten;
human metabolite;
plant metabolite
homocystine[no description available]low00amino acid zwitterion;
homocystines		human metabolite
glycocholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
epitestosterone[no description available]low0017alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen antagonist;
human metabolite
ninhydrin[no description available]low00aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
indican[no description available]low00aryl sulfate;
indoles		human metabolite
suberic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
hexadecanedioic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
pyridoxamine dihydrochloride[no description available]low00hydrochloride;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
aceturic acid[no description available]low00N-acetyl-amino acid;
N-acylglycine		human metabolite
myristic acid[no description available]low00long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
glycylglycine[no description available]low00dipeptide zwitterion;
dipeptide		human metabolite
lignoceric acid[no description available]low00straight-chain saturated fatty acid;
very long-chain fatty acid		Daphnia tenebrosa metabolite;
human metabolite;
plant metabolite;
volatile oil component
18-hydroxycorticosterone[no description available]low0011beta-hydroxy steroid;
18-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo steroid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
2-hydroxybutyric acid[no description available]low002-hydroxy monocarboxylic acid;
hydroxybutyric acid		algal metabolite;
human metabolite
3-methylhexane[no description available]low00alkane;
volatile organic compound		human metabolite
ethylmalonic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
galactitol[no description available]low00hexitolEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
2-hydroxyphenylacetic acid[no description available]low00hydroxy monocarboxylic acid;
phenols		human metabolite;
mouse metabolite
5-methyl-2-furfural[no description available]low00aldehyde;
furans		EC 2.2.1.6 (acetolactate synthase) inhibitor;
flavouring agent;
human metabolite;
Maillard reaction product
2-hexanol[no description available]low00hexanol;
secondary alcohol		human metabolite;
plant metabolite;
semiochemical
1,1,3,3-tetramethylurea[no description available]low00ureashuman metabolite
glycochenodeoxycholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
isocaproic acid[no description available]low00branched-chain saturated fatty acid;
medium-chain fatty acid;
methyl-branched fatty acid		human metabolite
dehydroepiandrosterone sulfate[no description available]low0017-oxo steroid;
steroid sulfate		EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite;
mouse metabolite
homoserine[no description available]low00amino acid zwitterion;
homoserine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
dodecanedioic acid[no description available]low00alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
human metabolite
deoxycytidine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyuridine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2'-deoxyadenosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cytidine diphosphate choline[no description available]low00nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
1-pentene-3-one[no description available]low00enoneflavouring agent;
genotoxin;
human metabolite;
plant metabolite
5 alpha-androstane-3 alpha,17 beta-diol[no description available]low00androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite
9,10-epoxystearic acid[no description available]low00epoxystearic acidhuman metabolite
5-hydroxyindole[no description available]low00hydroxyindoleshuman metabolite
beta-hydroxymyristic acid[no description available]low003-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
long-chain fatty acid		bacterial metabolite;
human metabolite
perillaldehyde[no description available]low00aldehyde;
olefinic compound		human metabolite;
mouse metabolite;
volatile oil component
tricosanoic acid[no description available]low00straight-chain saturated fatty acid;
very long-chain fatty acid		Daphnia magna metabolite;
human metabolite;
plant metabolite
uridine diphosphate glucuronic acid[no description available]low00UDP-D-glucuronic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
tetrahydropapaveroline[no description available]low00benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
isoquinolinol		human metabolite
dithiothreitol[no description available]low001,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
cyclic cmp[no description available]low003',5'-cyclic pyrimidine nucleotidehuman metabolite
furoylglycine[no description available]low00furans;
N-acylglycine		human metabolite
3,3',5'-triiodothyronine[no description available]low00iodothyroninehuman metabolite
hypochlorous acid[no description available]low00chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
urobilinogen[no description available]low00bilaneshuman metabolite
estetrol[no description available]low0015alpha-hydroxy steroid;
16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid;
steroid hormone		estrogen receptor agonist;
estrogen;
human metabolite;
human xenobiotic metabolite;
oral contraceptive
iron[no description available]low00divalent metal cation;
iron cation;
monoatomic dication		cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
1-methyladenosine[no description available]low00methyladenosinehuman metabolite
iodine[no description available]low00halide anion;
monoatomic iodine		human metabolite
nonanal[no description available]low00medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		human metabolite;
plant metabolite
dimethylacetamide[no description available]low00acetamides;
monocarboxylic acid amide		human metabolite
ursodeoxycholic acid[no description available]low00bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
pregnanolone[no description available]low003-hydroxy-5beta-pregnan-20-one;
3alpha-hydroxy steroid		human metabolite;
intravenous anaesthetic;
sedative
s-adenosylmethionine[no description available]low00sulfonium betainehuman metabolite
acetylgalactosamine[no description available]low00N-acetyl-D-hexosamine;
N-acetylgalactosamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
paclitaxel[no description available]low00taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
norsalsolinol[no description available]low00isoquinolinolanimal metabolite;
apoptosis inducer;
human metabolite;
marine metabolite
2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline[no description available]low00isoquinolinol;
tertiary amino compound		human metabolite;
neurotoxin;
rat metabolite
d-lactic acid[no description available]low002-hydroxypropanoic acidEscherichia coli metabolite;
human metabolite
xanthosine[no description available]low00purines D-ribonucleoside;
xanthosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
1,5-anhydroglucitol[no description available]low00anhydro sugarhuman metabolite
3-methylhistidine[no description available]low00L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion		human metabolite;
Saccharomyces cerevisiae metabolite
5-methylcytosine[no description available]low00methylcytosine;
pyrimidines		human metabolite
n-acetylaspartic acid[no description available]low00N-acetyl-L-amino acid;
N-acyl-L-aspartic acid		antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite
deoxyuridine triphosphate[no description available]low00deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
homocitrulline[no description available]low00amino acid zwitterion;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid;
ureas		human metabolite;
mouse metabolite
2'-deoxycytidine 5'-triphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
aica ribonucleotide[no description available]low001-(phosphoribosyl)imidazolecarboxamide;
aminoimidazole		cardiovascular drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
n-acetylserine[no description available]low00acetyl-L-serine;
N-acetyl-L-amino acid		human metabolite
o-4-methylthymine[no description available]low00aromatic ether;
methylthymine		human metabolite
tetraiodothyroacetic acid[no description available]low002-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid		apoptosis inducer;
human metabolite;
thyroid hormone
omega-aminocaprylic acid[no description available]low00medium-chain fatty acid;
omega-amino fatty acid		human metabolite
2-methoxyestradiol[no description available]low0017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
parabanic acid[no description available]low00hydracid;
imidazolidinone		human metabolite
n-acetyl-l-arginine[no description available]low00N-acetyl-L-amino acidhuman metabolite
cystine[no description available]low00cystine zwitterion;
cystine;
L-cysteine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
6-methyladenine[no description available]low006-alkylaminopurine;
methyladenine		human metabolite
phenylacetylglycine[no description available]low00monocarboxylic acid amide;
monocarboxylic acid;
N-acylglycine		human metabolite;
mouse metabolite
hydracrylic acid[no description available]low003-hydroxy monocarboxylic acid;
omega-hydroxy-short-chain fatty acid		Escherichia coli metabolite;
human metabolite
hordenine[no description available]low00phenethylamine alkaloidhuman metabolite;
mouse metabolite
4-methoxyestradiol[no description available]low0017beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols		estrogen;
human metabolite;
rat metabolite
glutaurine[no description available]low00dipeptide zwitterion;
dipeptide;
L-glutamine derivative;
sulfonic acid		anticonvulsant;
anxiolytic drug;
hormone;
human metabolite;
mammalian metabolite;
mouse metabolite
plasmenylserine[no description available]low00O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
ubiquinone-o[no description available]low00ubiquinonesEscherichia coli metabolite;
human metabolite
beta-hydroxyisovaleric acid[no description available]low003-hydroxy monocarboxylic acidhuman metabolite
n-acetylhistamine[no description available]low00acetamides;
imidazoles		human metabolite
indole-3-carboxylic acid[no description available]low00indol-3-yl carboxylic acidbacterial metabolite;
human metabolite
5-hydroxymethylcytosine[no description available]low00aminopyrimidine;
aromatic primary alcohol;
nucleobase analogue;
pyrimidone		human metabolite;
mouse metabolite
n-acetylglutamic acid[no description available]low00N-acetyl-L-amino acid;
N-acyl-L-glutamic acid		human metabolite;
Saccharomyces cerevisiae metabolite
2,5-dihydroxybenzaldehyde[no description available]low00dihydroxybenzaldehydehuman metabolite;
mouse metabolite;
Penicillium metabolite
D-serine[no description available]low00D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist
D-alanine[no description available]low00alanine zwitterion;
alanine;
D-alpha-amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite
2-ketopentanoic acid[no description available]low002-oxo monocarboxylic acid;
oxopentanoic acid		human metabolite
hydroxyindoleacetaldehyde[no description available]low00hydroxyindoles;
indoleacetaldehyde		human metabolite;
mouse metabolite
leucylleucine[no description available]low00dipeptide;
L-aminoacyl-L-amino acid zwitterion		human metabolite;
Mycoplasma genitalium metabolite
5-hydroxymethyluracil[no description available]low00primary alcohol;
pyrimidone		human metabolite
12-hydroxydodecanoic acid[no description available]low00omega-hydroxy-medium-chain fatty acidhuman metabolite
decane-1,2-diol[no description available]low00glycol;
volatile organic compound		anti-inflammatory agent;
antioxidant;
human metabolite
4-nitrophenyl sulfate[no description available]low00aryl sulfate;
C-nitro compound		human metabolite
glucose-1,6-bisphosphate[no description available]low00D-glucose 1,6-bisphosphateEscherichia coli metabolite;
human metabolite
biotinamide[no description available]low00biotins;
monocarboxylic acid amide		human metabolite
3,4-dihydroxymandelic acid[no description available]low002-hydroxy monocarboxylic acid;
catechols		antioxidant;
drug metabolite;
human metabolite;
mouse metabolite
3-hydroxymandelic acid[no description available]low002-hydroxy monocarboxylic acid;
phenols		human metabolite
n-acetylalanine[no description available]low00L-alanine derivative;
N-acetyl-L-amino acid		human metabolite;
Saccharomyces cerevisiae metabolite
17-alpha-hydroxypregnenolone[no description available]low0017alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
hydroxypregnenolone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
mephentermine[no description available]low002-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite
2-pinene oxide[no description available]low00epoxide;
pinane monoterpenoid		bacterial xenobiotic metabolite;
fragrance;
human metabolite
1-methylhistidine[no description available]low00L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion		human metabolite
3-hydroxybutyric acid[no description available]low003-hydroxybutyric acid;
ketone body		fungal metabolite;
human metabolite;
pheromone
L-2-aminoadipic acid[no description available]low002-aminoadipic acidEscherichia coli metabolite;
human metabolite
testosterone acetate[no description available]low003-oxo-Delta(4) steroid;
androstanoid;
sterol ester		human metabolite
phenylacetylglutamine[no description available]low00N(2)-phenylacetylglutaminehuman metabolite
5beta-pregnane-3,20-dione[no description available]low0020-oxo steroid;
3-oxo-5beta-steroid;
C21-steroid		human metabolite;
mouse metabolite
brexanolone[no description available]low003-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative
5-alpha-dihydroprogesterone[no description available]low0020-oxo steroid;
3-oxo-5alpha-steroid;
C21-steroid hormone		human metabolite;
progestogen
n-epsilon-acetyllysine[no description available]low00acetyl-L-lysine;
amino acid zwitterion;
N(6)-acyl-L-lysine		human metabolite
2-hydroxyhexadecanoic acid[no description available]low002-hydroxy fatty acid;
hydroxypalmitic acid		human metabolite
19-oxo-delta(4) androstene-3,17-dione[no description available]low0017-oxo steroid;
19-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid;
steroid aldehyde		human metabolite
gamma-glutamylglutamate[no description available]low00dipeptidehuman metabolite
indole-3-lactic acid[no description available]low00hydroxy monocarboxylic acid;
indol-3-yl carboxylic acid		human metabolite
n(alpha)-acetyllysine[no description available]low00acetyl-L-lysine;
amino acid zwitterion		human metabolite
glycyl-l-phenylalanine[no description available]low00dipeptide zwitterion;
dipeptide		human metabolite;
metabolite
5,6-dihydrothymine[no description available]low00pyrimidonehuman metabolite;
metabolite;
mouse metabolite
gamma-glutamyltyrosine[no description available]low00dicarboxylic acid;
dipeptide;
phenols;
primary amino compound;
secondary carboxamide		human metabolite
2-hydroxyisovaleric acid[no description available]low002-hydroxy monocarboxylic acidhuman metabolite
aminomalonic acid[no description available]low00amino dicarboxylic acidDaphnia magna metabolite;
human metabolite
zymostenol[no description available]low003beta-sterol;
cholestanoid		human metabolite;
mouse metabolite
16-hydroxydehydroepiandrosterone[no description available]low0016alpha-hydroxy steroid;
17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid;
secondary alpha-hydroxy ketone		human metabolite;
mouse metabolite
cortisol 21-sulfate[no description available]low0011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
cortisol ester;
steroid sulfate;
tertiary alpha-hydroxy ketone		human metabolite
1,2-distearoylphosphatidylethanolamine[no description available]low00phosphatidylethanolamine zwitterion;
phosphatidylethanolamine		human metabolite
hydrogen sulfite[no description available]low00sulfur oxoanionhuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
aflatoxin b1-2,3-oxide[no description available]low00aflatoxinhuman metabolite
fructose 2,6-diphosphate[no description available]low00D-fructofuranose 2,6-bisphosphatehuman metabolite;
mouse metabolite
3,3'-diiodothyronine[no description available]low003,3'-diiodothyronine;
amino acid zwitterion		human metabolite
l-lactic acid[no description available]low00(2S)-2-hydroxy monocarboxylic acid;
2-hydroxypropanoic acid		Escherichia coli metabolite;
human metabolite
propionylcarnitine[no description available]low00O-acylcarnitineanalgesic;
antirheumatic drug;
cardiotonic drug;
human metabolite;
peripheral nervous system drug
hypotaurine[no description available]low00aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite
testosterone 17-glucosiduronate[no description available]low003-oxo steroid;
beta-D-glucosiduronic acid;
enone;
steroid glucosiduronic acid		human metabolite
3-chloro-L-tyrosine[no description available]low00chloroamino acid;
L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monochlorobenzenes;
non-proteinogenic L-alpha-amino acid		biomarker;
human metabolite
androsterone glucuronide[no description available]low00beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
metabolite;
mouse metabolite
selenomethylselenocysteine[no description available]low00non-proteinogenic alpha-amino acid;
selenocysteines		antineoplastic agent;
human metabolite
1,5(10)-estradiene-3,4,17-trione[no description available]low0017-oxo steroid;
3-oxo-Delta(1) steroid;
orthoquinones		human metabolite
s-sulphocysteine[no description available]low00organic thiosulfate;
S-substituted L-cysteine		human metabolite;
plant metabolite
estrone-3-glucuronide[no description available]low0017-oxo steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
mouse metabolite
3,4-dihydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
catechols;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
1-hydroxyethyl radical[no description available]low00organic anionhuman metabolite;
Saccharomyces cerevisiae metabolite
deoxyhypusine[no description available]low00L-lysine derivative;
non-proteinogenic L-alpha-amino acid		human metabolite
3,7,12-trihydroxycoprostanic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
cholestanoic acid;
hydroxy monocarboxylic acid		human metabolite
triiodothyronine sulfate[no description available]low00aryl sulfate;
O-sulfoamino acid		human metabolite
3,7,12-trihydroxycholestan-26-oic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
hydroxy monocarboxylic acid;
steroid acid		human metabolite
erythrose 4-phosphate[no description available]low00erythrose phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
n(8)-acetylspermidine[no description available]low00acetylspermidineEscherichia coli metabolite;
human metabolite
7 alpha-hydroxy-4-cholesten-3-one[no description available]low003-oxo-Delta(4) steroid;
7alpha-hydroxy steroid;
cholestanoid		human metabolite;
mouse metabolite
pristanic acid[no description available]low00branched-chain saturated fatty acid;
long-chain fatty acid;
methyl-branched fatty acid		human metabolite
gamma-glutamylcysteine[no description available]low00gamma-glutamylcysteineEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
3-carboxy-4-methyl-5-propyl-2-furanpropionic acid[no description available]low00dicarboxylic acid;
furoic acid		human metabolite;
uremic toxin
dehydroalanine[no description available]low002,3-dehydroamino acid;
alpha,beta-unsaturated monocarboxylic acid;
amino acid zwitterion;
enamine;
non-proteinogenic alpha-amino acid		alkylating agent;
human metabolite;
mouse metabolite
hypothiocyanite ion[no description available]low00one-carbon compound;
sulfur oxoacid		antibacterial agent;
antifungal agent;
antiviral agent;
human metabolite;
oxidising agent;
rat metabolite
3-c-methylerythritol[no description available]low00tetritolhuman metabolite
succinylacetoacetate[no description available]low00alpha,omega-dicarboxylic acid;
beta-diketone		human metabolite
isoursodeoxycholic acid[no description available]low00dihydroxy-5beta-cholanic acidhuman metabolite
mannitol-1-phosphate[no description available]low00alditol 1-phosphate;
hexitol phosphate		Escherichia coli metabolite;
human metabolite
triiodothyronine[no description available]low00tetrahydrothiophenes;
thiolactone		human metabolite
kinetensin[no description available]low00oligopeptidehistamine releasing agent;
human metabolite
estra-1(10),4-diene-2,3,17-trione[no description available]low0017-oxo steroid;
3-oxo-Delta(4) steroid;
orthoquinones		human metabolite
2'-deoxycytidine diphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
n-methylserotonin[no description available]low00phenols;
tryptamines		human metabolite;
plant metabolite
gamma-glutamylglutamine[no description available]low00dipeptidehuman metabolite
3,4-dihydroxybutanoic acid[no description available]low003-hydroxy fatty acid;
omega-hydroxy-short-chain fatty acid		human metabolite
n-palmitoylglycine[no description available]low00fatty amide;
N-acylglycine 16:0		human metabolite;
marine metabolite
gamma-glutamyl-leucine[no description available]low00glutamyl-L-amino acidhuman metabolite
ribulose[no description available]low00ribuloseEscherichia coli metabolite;
human metabolite
3,4-dihydroxyphenylglycolaldehyde[no description available]low00catechols;
hydroxyaldehyde		human metabolite;
mouse metabolite;
neurotoxin
androsterone sulfate[no description available]low0017-oxo steroid;
androstanoid;
steroid sulfate		human metabolite;
mouse metabolite
3,7,12-trihydroxycoprostane[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
saccharopine[no description available]low00amino acid opine;
L-lysine derivative		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
allysine[no description available]low00allysine;
amino acid zwitterion;
aminoadipate semialdehyde;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
orotidylic acid[no description available]low00pyrimidine ribonucleoside 5'-monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
allocholic acid[no description available]low0012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
allo-bile acid;
C24-steroid		human metabolite;
marine metabolite;
rat metabolite
beta-ureidoisobutyric acid[no description available]low00ureidocarboxylic acidhuman metabolite;
mouse metabolite
kynurenine[no description available]low00amino acid zwitterion;
kynurenine;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
nicotinate ribonucleoside[no description available]low00ammonium betainehuman metabolite
n(6)-(n-threonylcarbonyl)adenosine[no description available]low00L-threonine derivative;
N-(adenosin-N(6)-ylcarbonyl)threonine		Escherichia coli metabolite;
human metabolite
sedoheptulose 7-phosphate[no description available]low00ketoheptose phosphate;
sedoheptulose derivative		Escherichia coli metabolite;
human metabolite;
mouse metabolite
histidinol[no description available]low00amino alcohol;
imidazoles		EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
thiocysteine[no description available]low00amino acid zwitterion;
S-substituted L-cysteine		human metabolite;
mouse metabolite
nicotinic acid adenine dinucleotide[no description available]low00nicotinic acid dinucleotideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol[no description available]low003beta-sterolhuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
bradykinin, des-phe(8)-des-arg(9)-[no description available]low00oligopeptidehuman metabolite;
rat metabolite
isobutyryl-1-carnitine[no description available]low00methyl-branched fatty acyl-L-carnitine;
O-isobutyrylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite
threitol[no description available]low00threitolhuman metabolite
biotin[no description available]low00biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
aceglutamide[no description available]low00N-acetyl-L-amino acid;
N(2)-acetylglutamine;
N(2)-acyl-L-glutamine		human metabolite
aflatoxin b1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
isospaglumic acid[no description available]low00dipeptidehuman metabolite
2'-deoxyadenosine triphosphate[no description available]low002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-ethylhydracrylic acid[no description available]low00branched-chain saturated fatty acid;
hydroxy fatty acid;
short-chain fatty acid		human metabolite
2-methyl-3-oxovaleric acid[no description available]low003-oxo monocarboxylic acidhuman metabolite
monoacetylcadaverine[no description available]low00acetamides;
N-substituted cadaverine;
primary amino compound;
secondary carboxamide		human metabolite
beta-citrylglutamic acid[no description available]low00N-acyl-L-glutamic acid;
tetracarboxylic acid		human metabolite;
iron chelator
maltotriose[no description available]low00maltotriose trisaccharidehuman metabolite
cholestane-3,7,12,26-tetrol[no description available]low0012alpha-hydroxy steroid;
26-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
beta-leucine[no description available]low00beta-amino acidhuman metabolite
2-methylbutyrylglycine[no description available]low00N-acylglycinehuman metabolite
neurotensin (1-8)[no description available]low00peptide zwitterion;
peptide		human metabolite
erythritol[no description available]low00butane-1,2,3,4-tetrolantioxidant;
human metabolite;
plant metabolite
cortisone[no description available]low0011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
5 alpha-androstane-3 beta,17 beta-diol[no description available]low0017beta-hydroxy steroid;
3beta-hydroxy steroid;
androstane-3,17-diol		Daphnia magna metabolite;
human metabolite
cholesteryl palmitate[no description available]low00cholesteryl esterhuman metabolite;
mouse metabolite
2-hydroxyestradiol[no description available]low0017beta-hydroxy steroid;
2-hydroxy steroid		carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug
5-hydroxyisourate[no description available]low00oxopurinehuman metabolite;
mouse metabolite
5-formyluracil[no description available]low00aldehyde;
nucleobase analogue;
pyrimidone		human metabolite;
mutagen
taurochenodeoxycholic acid[no description available]low00bile acid taurine conjugatehuman metabolite;
mouse metabolite
5'-methylthioadenosine[no description available]low00thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5'-deoxyadenosine[no description available]low005'-deoxyribonucleoside;
adenosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
isomaltose[no description available]low00glycosylglucosehuman metabolite;
metabolite;
mouse metabolite
n-acetylneuraminic acid[no description available]low00N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
glucosamine 6-phosphate[no description available]low002-amino-2-deoxy-D-glucopyranose 6-phosphatehuman metabolite;
Saccharomyces cerevisiae metabolite
carnosine[no description available]low00amino acid zwitterion;
dipeptide		anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent
5-hydroxytryptophan[no description available]low005-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
plant metabolite
dopaquinone[no description available]low001,2-benzoquinones;
amino acid zwitterion;
L-phenylalanine derivative		human metabolite;
mouse metabolite
pantetheine[no description available]low00pantetheines;
thiol		human metabolite;
metabolite;
mouse metabolite
tryptophanamide[no description available]low00amino acid amide;
tryptophan derivative		human metabolite
5-diphosphomevalonic acid[no description available]low00carboxyalkyl phosphatehuman metabolite;
mouse metabolite
cysteinylglycine[no description available]low00dipeptide zwitterion;
dipeptide		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
monoiodotyrosine[no description available]low00amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite
taurolithocholic acid[no description available]low00bile acid taurine conjugate;
monocarboxylic acid amide		human metabolite
n'-formylkynurenine[no description available]low00amino acid zwitterion;
N-formylkynurenine;
non-proteinogenic amino acid derivative;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
fuculose 1-phosphate[no description available]low00deoxyaldohexose phosphatehuman metabolite
nicotinamide-beta-riboside[no description available]low00N-glycosylnicotinamide;
pyridine nucleoside		geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4-hydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
trimethyllysine[no description available]low00alpha-amino-acid cationhuman metabolite;
mouse metabolite
inositol 3,4-bisphosphate[no description available]low00myo-inositol bisphosphatehuman metabolite;
mouse metabolite
n-acetylglucosamine-1-phosphate[no description available]low00N-acetyl-D-glucosamine 1-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
2-hydroxyestrone[no description available]low002-hydroxy steroid;
catechols		human metabolite
2-methoxyestrone[no description available]low0017-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols		human metabolite;
mouse metabolite
cortodoxone[no description available]low00deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
estradiol-3-glucuronide[no description available]low0017beta-hydroxy steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
mouse metabolite
acetyl adenylate[no description available]low005'-acylphosphoadenosinhuman metabolite;
mouse metabolite
epiandrosterone[no description available]low0017-oxo steroid;
3beta-hydroxy steroid;
androstanoid		androgen;
human metabolite
4,4-dimethylcholesta-8,14,24-trienol[no description available]low003beta-sterol;
Delta(14) steroid		human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
enkephalin, methionine[no description available]low00pentapeptide;
peptide zwitterion		analgesic;
antineoplastic agent;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist
7-ketolithocholic acid[no description available]low003alpha-hydroxy steroid;
bile acid;
monohydroxy-5beta-cholanic acid;
oxo-5beta-cholanic acid		human metabolite
dephosphocoenzyme a[no description available]low00adenosine 5'-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
ribothymidine[no description available]low00methyluridineantigen;
Escherichia coli metabolite;
human metabolite
docosahexaenoate[no description available]low00docosahexaenoic acid;
omega-3 fatty acid		algal metabolite;
antineoplastic agent;
Daphnia tenebrosa metabolite;
human metabolite;
mouse metabolite;
nutraceutical
tetragastrin[no description available]low00peptidyl amide;
tetrapeptide		anxiogenic;
human metabolite
hexanoyl-coenzyme a[no description available]low00medium-chain fatty acyl-CoAEscherichia coli metabolite;
human metabolite;
mouse metabolite
enkephalin, leucine[no description available]low00pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
tyrosine o-sulfate[no description available]low00aryl sulfate;
L-tyrosine derivative;
O-sulfoamino acid		human metabolite
retinaldehyde[no description available]low00retinal;
vitamin A		gap junctional intercellular communication inhibitor;
human metabolite;
mouse metabolite
thyrotropin-releasing hormone[no description available]low00peptide hormone;
tripeptide		human metabolite
n-methylproline[no description available]low00L-alpha-amino acid zwitterion;
L-proline derivative;
tertiary amino compound		human metabolite;
plant metabolite
citraconic acid[no description available]low00dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
flavin-adenine dinucleotide[no description available]low00flavin adenine dinucleotide;
vitamin B2		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group
flavin mononucleotide[no description available]low00flavin mononucleotide;
vitamin B2		bacterial metabolite;
coenzyme;
cofactor;
human metabolite;
mouse metabolite
mannose 1-phosphate[no description available]low00mannose phosphatefundamental metabolite;
human metabolite
glycerylphosphorylcholine[no description available]low00phosphocholines;
sn-glycerol 3-phosphates		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neuroprotective agent;
parasympatholytic;
Saccharomyces cerevisiae metabolite
urocanic acid[no description available]low00urocanic acidhuman metabolite
cysteine sulfinic acid[no description available]low00organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite
cholesterol acetate[no description available]low00acetate ester;
cholesteryl ester		human metabolite
1,6-anhydro-beta-glucopyranose[no description available]low00anhydrohexoseArabidopsis thaliana metabolite;
biomarker;
human metabolite
glycylvaline[no description available]low00dipeptidehuman metabolite
sodium taurodeoxycholate[no description available]low00bile acid taurine conjugatehuman metabolite
estrone sulfate[no description available]low0017-oxo steroid;
steroid sulfate		human metabolite;
mouse metabolite
hydroxylysine[no description available]low005-hydroxylysine;
hydroxy-L-lysine		human metabolite
glycodeoxycholic acid[no description available]low00bile acid glycine conjugatehuman metabolite
isobutyryl-coenzyme a[no description available]low00methyl-branched fatty acyl-CoA;
short-chain fatty acyl-CoA		human metabolite;
mouse metabolite
galactaric acid[no description available]low00hexaric acidhuman metabolite
dihydroxycoprostane[no description available]low003alpha-hydroxy steroid;
7alpha-hydroxy steroid		human metabolite;
mouse metabolite
angiotensin i, ile(5)-[no description available]low00angiotensin;
peptide zwitterion		human metabolite;
neurotransmitter agent
fructosyl-glycine[no description available]low00fructosamine;
glycine derivative;
glyco-amino acid		human metabolite
arachidoyl-coenzyme a[no description available]low0011,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA		human metabolite
lignoceroyl-coenzyme a[no description available]low00very long-chain fatty acyl-CoAhuman metabolite;
Saccharomyces cerevisiae metabolite
5-hydroxybenzimidazole[no description available]low00benzimidazoles;
phenols		bacterial metabolite;
human metabolite;
rat metabolite
n-carbamylglutamate[no description available]low00glutamic acid derivative;
ureas		human metabolite
citramalate[no description available]low00dicarboxylic acid dianionhuman metabolite;
plant metabolite
4-cresol sulfate[no description available]low00aryl sulfategut flora metabolite;
human metabolite;
uremic toxin
bilirubin[no description available]low00biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
leukotriene a4[no description available]low00epoxy fatty acid;
leukotriene;
long-chain fatty acid;
oxylipin;
polyunsaturated fatty acid		human metabolite;
mouse metabolite;
plant metabolite
prostaglandin b1[no description available]low00prostaglandins Bhuman metabolite
psychosine[no description available]low00glycosylsphingoidhuman metabolite
ubiquinone 9[no description available]low00ubiquinonesantioxidant;
human metabolite
beta carotene[no description available]low00carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
11-cis-retinal[no description available]low00retinalchromophore;
human metabolite;
mouse metabolite
leukotriene b4[no description available]low00dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
leukotriene c4[no description available]low00leukotrienebronchoconstrictor agent;
human metabolite;
mouse metabolite
prostaglandin f2beta[no description available]low00prostaglandins Fbetahuman metabolite
8,11,14-eicosatrienoic acid[no description available]low00fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical
15-keto-5,8,11,13-eicosatetraenoic acid[no description available]low00oxoicosatetraenoic acidhuman metabolite
alprostadil[no description available]low00prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent
15-hydroxy-5,8,11,13-eicosatetraenoic acid[no description available]low00(5Z,8Z,11Z,13E)-15-HETEhuman metabolite;
mouse metabolite
5-hydroxy-6,8,11,14-eicosatetraenoic acid[no description available]low00HETEhuman metabolite;
mouse metabolite
leukotriene d4[no description available]low00dipeptide;
leukotriene;
organic sulfide		bronchoconstrictor agent;
human metabolite;
mouse metabolite
prostaglandin b2[no description available]low00prostaglandins Bhuman metabolite
prostaglandin g2[no description available]low00prostaglandins Ghuman metabolite;
mouse metabolite
11-dehydro-thromboxane b2[no description available]low00thromboxanehuman metabolite
lipoxin a4[no description available]low00hydroxy polyunsaturated fatty acid;
lipoxin;
long-chain fatty acid		human metabolite;
metabolite
gamma-linolenic acid[no description available]low00linolenic acid;
omega-6 fatty acid		human metabolite;
mouse metabolite;
plant metabolite
prostaglandin e3[no description available]low00prostaglandins Ehuman metabolite
leukotriene f-4[no description available]low00dipeptide;
leukotriene;
organic sulfide		human metabolite
prostaglandin f1[no description available]low00prostaglandins Falphahuman metabolite
previtamin d(3)[no description available]low00D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol		human metabolite
brassicasterol[no description available]low003beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		algal metabolite;
animal metabolite;
biomarker;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
human metabolite;
marine metabolite;
plant metabolite;
sterol biosynthesis inhibitor
retinoyl beta-glucuronide[no description available]low00glucuronic acids;
retinoid		human metabolite
coenzyme q10[no description available]low00ubiquinonesantioxidant;
ferroptosis inhibitor;
human metabolite
prostaglandin d3[no description available]low00prostaglandins Dhuman metabolite
glyceryl 2-arachidonate[no description available]low002-acylglycerol 20:4;
endocannabinoid		human metabolite
tocotrienol, alpha[no description available]low00tocotrienol;
vitamin E		ferroptosis inhibitor;
human metabolite;
neuroprotective agent;
plant metabolite
menatetrenone[no description available]low00menaquinoneanti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent
phthioic acid[no description available]low00branched-chain saturated fatty acid;
fatty acid 26:0;
methyl-branched fatty acid;
very long-chain fatty acid		Aspergillus metabolite;
human metabolite
2-decenoic acid[no description available]low002-decenoic acidhuman metabolite
9,11-linoleic acid[no description available]low00octadeca-9,11-dienoic acidanti-inflammatory agent;
antiatherogenic agent;
antineoplastic agent;
apoptosis inducer;
bacterial xenobiotic metabolite;
human metabolite
17-phenyltrinorprostaglandin e2[no description available]low00alicyclic ketone;
beta-hydroxy ketone;
hydroxy monocarboxylic acid;
olefinic compound;
oxo monocarboxylic acid;
prostanoid;
secondary alcohol		human metabolite;
prostaglandin receptor agonist
thromboxane b2[no description available]low00thromboxanes Bhuman metabolite;
mouse metabolite
thromboxane b3[no description available]low00thromboxanes Bhuman metabolite;
mouse metabolite
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]low00(5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid;
HETE		human metabolite;
pro-angiogenic agent
20-hydroxy-5,8,11,14-eicosatetraenoic acid[no description available]low00HETE;
hydroxy monocarboxylic acid		human metabolite;
mouse metabolite
5-oxo-6,8,11,14-eicosatetraenoic acid[no description available]low00oxoicosatetraenoic acidhuman metabolite;
immunomodulator;
mouse metabolite
8-isoprostaglandin e2[no description available]low00cyclic ketone;
diol;
prostanoid;
secondary alcohol		bronchoconstrictor agent;
human metabolite;
rat metabolite;
vasoconstrictor agent
oleylamide[no description available]low00primary fatty amidehuman metabolite;
plant metabolite
monolinolein[no description available]low001-acylglycerol 18:2;
rac-1-monoacylglycerol		antiviral agent;
human metabolite;
plant metabolite
1,25-dihydroxy-24-oxo-vitamin d3[no description available]low00hydroxycalciol;
oxocalciol;
tertiary alpha-hydroxy ketone		human metabolite
calcifediol[no description available]low00D3 vitamins;
diol;
hydroxycalciol		bone density conservation agent;
human metabolite;
metabolite;
mouse metabolite;
nutraceutical
hyodeoxycholic acid[no description available]low005beta-cholanic acids;
6alpha,20xi-murideoxycholic acid;
bile acid;
C24-steroid		human metabolite;
mouse metabolite
vitamin k 1[no description available]low00phylloquinones;
vitamin K		cofactor;
human metabolite;
plant metabolite
cerium[no description available]low00CE(18:2);
cholesteryl octadeca-9,12-dienoate		human metabolite;
mouse metabolite
xylulose[no description available]low00xyluloseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
11-dehydrocorticosterone[no description available]low0011-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
1-butyl oleate[no description available]low00fatty acid esterhuman metabolite
8-hydroxyadenine[no description available]low006-aminopurines;
heteroaryl hydroxy compound;
nucleobase analogue;
oxopurine		bacterial metabolite;
human metabolite
erucyl amide[no description available]low0013-docosenamideEC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite;
mammalian metabolite;
plant metabolite;
rat metabolite
vitamin mk 8[no description available]low00menaquinoneEscherichia coli metabolite;
human metabolite
2,3-oxidosqualene[no description available]low002,3-epoxysqualenehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2-keto-4-hydroxyglutarate[no description available]low00oxo dicarboxylatehuman metabolite;
Saccharomyces cerevisiae metabolite
deoxyribose[no description available]low00deoxypentosehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
iditol[no description available]low00iditolfungal metabolite;
human metabolite
glutamate[no description available]low00glutamate(1-);
polar amino acid zwitterion		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
human metabolite;
Saccharomyces cerevisiae metabolite
fumarates[no description available]low00butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
cerotate[no description available]low00fatty acid anion 26:0;
omega-methyl fatty acid anion;
very long-chain fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine triphosphate[no description available]low00nucleoside 5'-triphoshate(4-)cofactor;
fundamental metabolite;
human metabolite
docosapentaenoic acid[no description available]low00docosapentaenoic acid;
omega-3 fatty acid		algal metabolite;
human metabolite
3-methylbutyrylcarnitine[no description available]low00C5-acylcarnitinehuman metabolite
hexanoylcarnitine[no description available]low00hexanoate ester;
O-acylcarnitine		human metabolite
linoleamide[no description available]low00primary fatty amidehuman metabolite
13-cis-retinal[no description available]low00retinalhuman metabolite
4-hydroxyretinoic acid[no description available]low00retinoid;
secondary allylic alcohol		human metabolite
4-oxo-2-nonenal[no description available]low00enal;
enone		human metabolite
biotinate[no description available]low00monocarboxylic acid anion;
vitamin B7		cofactor;
human metabolite;
Saccharomyces cerevisiae metabolite
6 beta-hydroxycortisol[no description available]low0011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
6beta-hydroxy steroid;
C21-steroid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mammalian metabolite;
probe
fuculose[no description available]low00deoxyketohexoseEscherichia coli metabolite;
human metabolite
gamma-glutamylvaline[no description available]low00glutamyl-L-amino acidhuman metabolite
ophthalmic acid[no description available]low00L-glutamine derivativebiomarker;
human metabolite
acetylcarnitine[no description available]low00O-acetylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)fundamental metabolite;
human metabolite
cyclic amp[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
1,23,25-trihydroxyvitamin d3[no description available]low00D3 vitamins;
hydroxy seco-steroid;
hydroxycalciol;
tetrol		human metabolite
phosphocreatine[no description available]low00phosphagen;
phosphoamino acid		human metabolite;
mouse metabolite
ursodoxicoltaurine[no description available]low00bile acid taurine conjugateanti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent
arachidonoylserotonin[no description available]low00N-acylserotonin;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
capsaicin receptor antagonist;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
human metabolite;
signalling molecule
homocarnosine[no description available]low00dipeptide zwitterion;
dipeptide;
homocarnosine;
L-histidine derivative;
N-acyl-L-alpha-amino acid anion;
N-acyl-L-alpha-amino acid		human metabolite
3-hydroxyproline[no description available]low003-hydroxyproline;
amino acid zwitterion;
D-proline derivative		bacterial metabolite;
human metabolite
octanoylcarnitine[no description available]low00O-octanoylcarnitine;
saturated fatty acyl-L-carnitine		human metabolite
palmitoylcarnitine[no description available]low00O-palmitoylcarnitine;
saturated fatty acyl-L-carnitine		EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
human metabolite;
mouse metabolite
cyclic 3',5'-thymidine monophosphate[no description available]low003',5'-cyclic pyrimidine nucleotidehuman metabolite
pristanal[no description available]low002-methyl-branched fatty aldehyde;
saturated fatty aldehyde		human metabolite
lanosten-3-ol-32-al[no description available]low0014alpha-formyl steroid;
3beta-sterol;
tetracyclic triterpenoid		human metabolite
thiamine pyrophosphate[no description available]low00organophosphate oxoanion;
vitamin B1		human metabolite;
Saccharomyces cerevisiae metabolite
adenosine monophosphate[no description available]low00nucleoside 5'-monophosphate(2-)cofactor;
fundamental metabolite;
human metabolite
cob(ii)alamin[no description available]low00cobalamincofactor;
human metabolite
nociceptin[no description available]low00organic molecular entity;
polypeptide		human metabolite;
rat metabolite
3-hydroxy-3-methyl-hexanoic acid[no description available]low003-hydroxy monocarboxylic acid;
volatile organic compound		human metabolite
uridine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)human metabolite;
Saccharomyces cerevisiae metabolite
n-acetylgalactosamine-1-phosphate[no description available]low00D-galactosamine 1-phosphatehuman metabolite
1-phospho-5-s-methylthioribulose[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
s-adenosylmethionine[no description available]low00organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
10-nitro-oleic acid[no description available]low00long-chain fatty acid;
monounsaturated fatty acid;
nitro fatty acid		human metabolite
ticrynafen[no description available]low00monocarboxylic acid anion;
organophosphate oxoanion		human metabolite
s-(1,2-dicarboxyethyl)cysteine[no description available]low00L-cysteine thioether;
tricarboxylic acid		human metabolite;
Maillard reaction product
neurotensin[no description available]low00peptide hormonehuman metabolite;
mitogen;
neurotransmitter;
vulnerary
apelin-13 peptide[no description available]low00oligopeptideantihypertensive agent;
autophagy inhibitor;
biomarker;
human metabolite;
neuroprotective agent
p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe[no description available]low00polypeptideapoptosis inhibitor;
human metabolite;
neuroprotective agent
taurolithocholic acid 3-sulfate[no description available]low00steroid sulfate oxoanionhuman metabolite
inositol 1,3,4-trisphosphate[no description available]low00inositol phosphate oxoanionhuman metabolite
diadenosine tetraphosphate[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
2-ketoarginine[no description available]low002-oxo monocarboxylic acid;
zwitterion		human metabolite;
mouse metabolite
adenosine diphosphate glucose[no description available]low00NDP-alpha-D-glucose(2-);
ribonucleoside 5'-diphosphate-alpha-D-glucose(2-)		human metabolite
nicotinate mononucleotide[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
oleoylcarnitine[no description available]low00monounsaturated fatty acyl-L-carnitineglycine transporter 2 inhibitor;
human metabolite
uridine diphosphate n-acetylgalactosamine[no description available]low00nucleotide-sugar oxoanionhuman metabolite
6-phosphogluconolactone[no description available]low00organophosphate oxoanionhuman metabolite;
Saccharomyces cerevisiae metabolite
3-hydroxyisovalerylcarnitine[no description available]low00O-acylcarnitinehuman metabolite
angiotensin i[no description available]low00angiotensin;
peptide zwitterion		antihypertensive agent;
cardioprotective agent;
human metabolite;
rat metabolite
9-PAHSA[no description available]low00FAHFA;
long-chain fatty acid		anti-inflammatory agent;
human metabolite;
hypoglycemic agent
angiotensin i[no description available]low00angiotensin;
peptide zwitterion		human metabolite;
neurotransmitter agent
lugdunin[no description available]low00homodetic cyclic peptide;
indoles;
macrocycle;
peptide antibiotic;
thiazolidines		human metabolite;
rat metabolite
deoxyguanosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
deoxyguanosine triphosphate[no description available]low00deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
7,8-dihydroneopterin[no description available]low00dihydropterin;
neopterins		Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine monophosphate[no description available]low00deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
guanosine diphosphate mannose[no description available]low00GDP-D-mannoseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
inosinic acid[no description available]low00inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
inosine[no description available]low00inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
inosine triphosphate[no description available]low00inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
sapropterin[no description available]low005,6,7,8-tetrahydrobiopterincoenzyme;
cofactor;
diagnostic agent;
human metabolite
folic acid[no description available]low00folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
dyspropterin[no description available]low00biopterins;
tetrahydropterin		human metabolite;
metabolite;
mouse metabolite
8-nitroguanosine 3',5'-cyclic monophosphate[no description available]low003',5'-cyclic purine nucleotide;
C-nitro compound		biomarker;
Brassica napus metabolite;
human metabolite;
signalling molecule
n(2),n(2)-dimethylguanosine[no description available]low00methylguanosinehuman metabolite
creatinine[no description available]low00imidazolidinone;
lactam		diagnostic agent;
human metabolite
apelin-12 peptide[no description available]low00oligopeptidebiomarker;
human blood serum metabolite;
human metabolite;
neuroprotective agent
ecdysone[no description available]low0014alpha-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
6-oxo steroid;
ecdysteroid		prohormone
ecdysterone[no description available]low0014alpha-hydroxy steroid;
20-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
ecdysteroid;
phytoecdysteroid		animal metabolite;
plant metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
2019 Novel Coronavirus Disease0low60
2019 Novel Coronavirus Infection0low60
2019-nCoV Disease0low60
2019-nCoV Infection0low60
Actinic Reticuloid Syndrome0low10
Acute Confusional Senile Dementia0low60
Acute Lung Injury0low20
Acute Lymphoid Leukemia0low30
Acute Myelogenous Leukemia0low10
Acute Myeloid Leukemia0low10
Acute Myeloid Leukemia with Maturation0low10
Acute Myeloid Leukemia without Maturation0low10
Acute-Phase Reaction0low10
Acute-Phase State0low10
Addison Disease and Cerebral Sclerosis0low10
Adenocarcinoma0low50
Adenocarcinoma Of Kidney0low10
Adenocarcinoma, Basal Cell0low50
Adenocarcinoma, Granular Cell0low50
Adenocarcinoma, Oxyphilic0low50
Adenocarcinoma, Renal0low10
Adenocarcinoma, Renal Cell0low10
Adenocarcinoma, Tubular0low50
Adenoma, Malignant0low50
Adrenal Cortex Cancer0low20
Adrenal Cortex Neoplasms0low20
Adrenocortical Cancer0low20
Adrenoleukodystrophy0low10
Adrenomyeloneuropathy0low10
African Swine Fever0low10
African Swine Fever Virus Infection0low10
Age-Related Macular Degeneration0low10
Age-Related Maculopathies0low10
Age-Related Maculopathy0low10
Aging0low40
AIDS, Simian0low10
Airflow Obstruction, Chronic0low10
ALD (Adrenoleukodystrophy)0low10
ALL, Childhood0low30
Allergic Encephalomyelitis0low10
Allergic Encephalomyelitis, Experimental0low10
alpha-LCAT Deficiency0low10
alpha-Lecithin-Cholesterol Acyltransferase Deficiency0low10
ALS - Amyotrophic Lateral Sclerosis0low20
Alzheimer Dementia0low60
Alzheimer Disease0low60
Alzheimer Disease, Early Onset0low60
Alzheimer Disease, Late Onset0low60
Alzheimer Sclerosis0low60
Alzheimer Syndrome0low60
Alzheimer Type Senile Dementia0low60
Alzheimer-Type Dementia (ATD)0low60
Alzheimer's Disease0low60
Alzheimer's Disease, Focal Onset0low60
Alzheimer's Diseases0low60
Amyotrophic Lateral Sclerosis0low20
Amyotrophic Lateral Sclerosis With Dementia0low20
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 10low20
Amyotrophic Lateral Sclerosis, Guam Form0low20
Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam0low20
Anaplastic Astrocytoma0low20
Aneurysm, Thoracic Aortic0low10
Angina at Rest0low10
Angina Pectoris0low10
Angina Pectoris, Unstable0low10
Angina, Preinfarction0low10
Angina, Unstable0low10
Angor Pectoris0low10
ANLL0low10
Anoxemia0low10
Anoxia0low10
Aortic Aneurysm, Thoracic0low10
Aortic Aneurysm, Thoracoabdominal0low10
Apolipoprotein B-100, Familial Defective0low10
Apolipoprotein B-100, Familial Ligand-Defective0low10
Arterial Diseases, Carotid0low10
Arterial Diseases, Common Carotid0low10
Arterial Diseases, External Carotid0low10
Arterial Diseases, Internal Carotid0low10
Arteriosclerosis0low140
Arteriosclerosis, Coronary0low20
Arthritis, Degenerative0low10
Arthroses0low10
Arthrosis0low10
Asfivirus Infection0low10
Astrocytoma0low20
Astrocytoma, Grade I0low20
Astrocytoma, Grade II0low20
Astrocytoma, Grade III0low20
Astrocytoma, Grade IV0low20
Astrocytoma, Protoplasmic0low20
Astrocytoma, Subependymal Giant Cell0low20
Astroglioma0low20
Atherogenesis0low140
Atheroma0low40
Atheromatous Plaque0low40
Atheromatous Plaques0low40
Atherosclerosis0low140
Atherosclerosis, Coronary0low20
Atherosclerotic Disease, Carotid0low10
Atherosclerotic Plaque0low40
Atherosclerotic Plaques0low40
ATLL0low10
Atrial Fibrillation0low10
Atrophy, Muscle0low10
Atypical Lipomatous Tumor0low10
Auricular Fibrillation0low10
Autoimmune Diabetes0low10
Autoimmune Disease0low10
Autoimmune Diseases0low10
Autoimmune Encephalomyelitis, Experimental0low10
Autoimmune Experimental Encephalomyelitis0low10
Autosomal Dominant Hereditary Spastic Paraplegia0medium32
Autosomal Dominant Spastic Paraplegia Hereditary0medium32
Autosomal Recessive Hereditary Spastic Paraplegia0medium32
Autosomal Recessive Spastic Paraplegia, Hereditary0medium32
Avian Diseases0low10
Bacterial Disease0low10
Bacterial Infection0low10
Bacterial Infections0low10
Benign Neoplasms0low50
Benign Neoplasms, Brain0low10
Biliary Calculi0low10
Biliary Calculi, Common Bile Duct0low10
Biliary Fistula0low10
Bird Diseases0low10
Blue-Eared Pig Disease0low20
Body Weight0low20
Bone Diseases, Developmental0low10
Bone Dysplasias0low10
Bone Loss, Osteoclastic0low10
Bone Resorption0low10
Brain Cancer0low10
Brain Inflammation0low10
Brain Metastases0low10
Brain Neoplasm, Primary0low10
Brain Neoplasms0low10
Brain Neoplasms, Benign0low10
Brain Neoplasms, Malignant0low10
Brain Neoplasms, Malignant, Primary0low10
Brain Neoplasms, Primary Malignant0low10
Brain Tumor, Primary0low10
Brain Tumor, Recurrent0low10
Brain Tumors0low10
Breast Cancer0low40
Breast Carcinoma0low40
Breast Neoplasms0low40
Breast Tumors0low40
Bronze Schilder Disease0low10
Calcification, Pathologic0low10
Calcinosis0low10
Calcinosis, Tumoral0low10
Cancer0low50
Cancer of Adrenal Cortex0low20
Cancer of Brain0low10
Cancer of Breast0low40
Cancer of Cervix0low20
Cancer of Colon0low30
Cancer of Kidney0low20
Cancer of Liver0low200
Cancer of Lung0low20
Cancer of Ovary0low20
Cancer of Prostate0low20
Cancer of Skin0low10
Cancer of Stomach0low10
Cancer of the Adrenal Cortex0low20
Cancer of the Brain0low10
Cancer of the Breast0low40
Cancer of the Cervix0low20
Cancer of the Colon0low30
Cancer of the Kidney0low20
Cancer of the Liver0low200
Cancer of the Lung0low20
Cancer of the Ovary0low20
Cancer of the Prostate0low20
Cancer of the Skin0low10
Cancer of the Stomach0low10
Cancer of the Uterine Cervix0low20
Cancer, Hepatocellular0low200
Carcinoma, Cribriform0low50
Carcinoma, Epidermoid0low10
Carcinoma, Granular Cell0low50
Carcinoma, Hepatocellular0low210
Carcinoma, Hypernephroid0low10
Carcinoma, Non-Small Cell Lung0low10
Carcinoma, Non-Small-Cell Lung0low10
Carcinoma, Ovarian Epithelial0low10
Carcinoma, Planocellular0low10
Carcinoma, Renal Cell0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Squamous Cell of Head and Neck0low10
Carcinoma, Thymic0low10
Carcinoma, Tubular0low50
Carotid Artery Diseases0low10
Carotid Artery Disorders0low10
Carotid Atherosclerosis0low10
Carotid Atherosclerotic Disease0low10
Cataract0low60
Cataract, Membranous0low60
Cell Transformation, Neoplastic0low20
Cell Transformation, Viral0low30
Cerebral Astrocytoma0low20
Cerebral Cholesterinosis0low10
Cerebral Infarction, Middle Cerebral Artery0low10
Cerebrotendinous Xanthomatosis0low10
Cervical Cancer0low20
Cervical Neoplasms0low20
Cervix Cancer0low20
Cervix Neoplasms0low20
Charcot Disease0low20
Charcot-Marie-Tooth Disease with Pyramidal Features, Autosomal Dominant0medium32
Childhood Cerebral Astrocytoma0low20
Chromophil Renal Cell Carcinoma0low10
Chromophobe Renal Cell Carcinoma0low10
Chronic Actinic Dermatitis0low10
Chronic Airflow Obstruction0low10
Chronic Hepatitis B0low10
Chronic Hepatitis B Virus Infection0low10
Chronic Hepatitis C0low10
Chronic Obstructive Airway Disease0low10
Chronic Obstructive Lung Disease0low10
Chronic Obstructive Pulmonary Disease0low10
Chronic Obstructive Pulmonary Diseases0low10
Cirrhosis0low10
Classical Swine Fever0low10
Clear Cell Renal Carcinoma0low10
Clear Cell Renal Cell Carcinoma0low10
CMT with Pyramidal Features0medium32
COAD0low10
Colitis0low10
Colitis Gravis0low10
Colitis, Granulomatous0low10
Colitis, Ulcerative0low10
Collecting Duct Carcinoma0low10
Collecting Duct Carcinoma (Kidney)0low10
Collecting Duct Carcinoma of the Kidney0low10
Colon Cancer0low30
Colon Neoplasms0low30
Colonic Cancer0low30
Colonic Neoplasms0low30
Colorectal Cancer0low20
Colorectal Carcinoma0low20
Colorectal Neoplasms0low20
Colorectal Tumors0low20
Common Bile Duct Calculi0low10
Common Bile Duct Gall Stone0low10
Common Bile Duct Gall Stones0low10
Common Bile Duct Gallstone0low10
Common Bile Duct Gallstones0low10
Common Carotid Artery Diseases0low10
Congenital Zika Syndrome0low20
Congenital Zika Virus Infection0low20
COPD0low10
Coronary Arteriosclerosis0low20
Coronary Artery Disease0low20
Coronary Artery Vasospasm0low10
Coronary Atherosclerosis0low20
Coronary Vasospasm0low10
Coronavirus Disease 20190low60
Coronavirus Disease-190low60
Coronavirus Infections0low40
COVID-190low60
COVID-19 Pandemic0low60
COVID-19 Pandemics0low60
COVID-19 Virus Disease0low60
COVID-19 Virus Infection0low60
COVID190low60
Crohn Disease0low10
Crohn's Disease0low10
Crohn's Enteritis0low10
Deficiency, Oxygen0low10
Deficiency, Protein0low10
Degenerative Diseases, Central Nervous System0low20
Degenerative Diseases, Nervous System0low20
Degenerative Diseases, Neurologic0low20
Degenerative Diseases, Spinal Cord0low20
Degenerative Neurologic Diseases0low20
Degenerative Neurologic Disorders0low20
Dementia With Amyotrophic Lateral Sclerosis0low20
Dementia, Alzheimer Type0low60
Dementia, Presenile0low60
Dementia, Primary Senile Degenerative0low60
Dementia, Senile0low60
Dermatitis, Actinic0low10
Dermatitis, Irritant0low10
Dermatitis, Primary Irritant0low10
Developmental Bone Disease0low10
Diabetes Mellitus0low10
Diabetes Mellitus, Adult-Onset0low10
Diabetes Mellitus, Brittle0low10
Diabetes Mellitus, Insulin-Dependent0low10
Diabetes Mellitus, Insulin-Dependent, 10low10
Diabetes Mellitus, Juvenile-Onset0low10
Diabetes Mellitus, Ketosis-Prone0low10
Diabetes Mellitus, Ketosis-Resistant0low10
Diabetes Mellitus, Maturity-Onset0low10
Diabetes Mellitus, Non Insulin Dependent0low10
Diabetes Mellitus, Non-Insulin-Dependent0low10
Diabetes Mellitus, Noninsulin Dependent0low10
Diabetes Mellitus, Noninsulin-Dependent0low10
Diabetes Mellitus, Slow-Onset0low10
Diabetes Mellitus, Stable0low10
Diabetes Mellitus, Sudden-Onset0low10
Diabetes Mellitus, Type 10low10
Diabetes Mellitus, Type 20low10
Diabetes Mellitus, Type I0low10
Diabetes Mellitus, Type II0low10
Diabetes, Autoimmune0low10
Diabetic Glomerulosclerosis0low10
Diabetic Kidney Disease0low10
Diabetic Nephropathies0low10
Diabetic Nephropathy0low10
Diarrhea0low10
Diathesis0low10
Disease Exacerbation0medium21
Disease Models, Animal0low180
Disease Progression0medium21
Disease Susceptibility0low10
Dyslipidemia0low10
Dyslipidemias0low10
Dyslipoproteinemias0low10
Dyslipoproteinemic Corneal Dystrophy0low10
Early Onset Alzheimer Disease0low60
Elevated Cholesterol0low50
Embolic Infarction, Middle Cerebral Artery0low10
Embolus, Middle Cerebral Artery0low10
Encephalitis0low10
Encephalitis, Rasmussen0low10
Encephalomyelitis, Allergic0low10
Encephalomyelitis, Autoimmune, Experimental0low10
Encephalomyelitis, Experimental Autoimmune0low10
Endometrioma0low10
Endometriosis0low10
Endotoxin Shock0low10
Enteritis, Granulomatous0low10
Enteritis, Regional0low10
Epithelial Neoplasms0low10
Epithelial Ovarian Cancer0low10
Epithelial Ovarian Carcinoma0low10
Experimental Allergic Encephalomyelitis0low10
Experimental Autoimmune Encephalomyelitis0low10
Experimental Hepatoma0low100
Experimental Hepatomas0low100
Experimental Liver Neoplasms0low100
Experimental Lung Inflammation0low10
Experimental Mammary Neoplasms0low10
Experimental Neoplasms0low10
External Carotid Artery Diseases0low10
Familial Alzheimer Disease (FAD)0low60
Familial Atrial Fibrillation0low10
Familial Combined Hyperlipoproteinemia0low10
Fatty Liver, Nonalcoholic0low20
Fatty Streak, Arterial0low40
Fetal Growth Restriction0low10
Fetal Growth Retardation0low10
Fever, Zika0low20
Fibrillary Astrocytoma0low20
Fibroatheroma0low40
Fibroatheromatous Plaques0low40
Fibrosarcoma0low10
Fibrosis0low10
Fish Diseases0low10
Fish-Eye Disease0low10
Focal Onset Alzheimer's Disease0low60
Fowl Paralysis0low10
Gall Stone0low10
Gall Stones0low10
Gall Stones, Common Bile Duct0low10
Gallstone0low10
Gallstones0low10
Gallstones, Common Bile Duct0low10
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Gehrig's Disease0low20
Gemistocytic Astrocytoma0low20
Genetic Predisposition0low10
Genetic Predisposition to Disease0low10
Genetic Susceptibility0low10
Giant Cell Glioblastoma0low20
Glandular and Epithelial Neoplasms0low10
Glandular Neoplasms0low10
Glial Cell Tumors0low10
Glioblastoma0low20
Glioblastoma Multiforme0low20
Glioma0low10
Glioma, Astrocytic0low20
Glomerulosclerosis, Diabetic0low10
Glucose Intolerance0low10
Grawitz Tumor0low10
Grippe0low10
Growth Retardation, Intrauterine0low10
Guam Disease0low20
Guam Form of Amyotrophic Lateral Sclerosis0low20
Hairy Cell Leukemia0low10
Head and Neck Squamous Cell Carcinoma0low10
Head And Neck Squamous Cell Carcinomas0low10
Hepatic Cancer0low200
Hepatic Neoplasms0low200
Hepatitis0low10
Hepatitis B Virus Infection, Chronic0low10
Hepatitis B, Chronic0low10
Hepatitis C0low20
Hepatitis C, Chronic0low10
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted0low20
Hepatoblastoma0low20
Hepatocellular Cancer0low200
Hepatocellular Carcinoma0low210
Hepatoma0low210
Hepatoma, Experimental0low100
Hepatoma, Morris0low100
Hepatoma, Novikoff0low100
Hepatomas, Experimental0low100
Hereditary Autosomal Dominant Spastic Paraplegia0medium32
Hereditary Autosomal Recessive Spastic Paraplegia0medium32
Hereditary Motor and Sensory Neuropathy 50medium32
Hereditary Motor And Sensory Neuropathy V0medium32
Hereditary Motor-Sensory Neuropathy with Pyramidal Signs0medium32
Hereditary Spastic Paraplegia0medium32
Hereditary Spastic Paraplegia, Autosomal Recessive0medium32
Hereditary X-Linked Recessive Spastic Paraplegia0medium32
Hereditary, Spastic Paraplegia, Autosomal Dominant0medium32
Hereditary, Spastic Paraplegia, X-Linked Recessive0medium32
Herpes Simplex0low10
Herpes Simplex Virus Infection0low10
High Cholesterol Levels0low50
HIV Coinfection0low20
HIV Infections0low20
HMSN 50medium32
HMSN Type V0medium32
HMSN V0medium32
HMSN V (Hereditary Motor and Sensory Neuropathy Type V)0medium32
HNSCC0low10
Hog Cholera0low10
Hormone-Dependent Neoplasms0low10
HPV Infection0low20
HTLV I Associated T Cell Leukemia Lymphoma0low10
HTLV-Associated Leukemia-Lymphoma0low10
HTLV-I-Associated T-Cell Leukemia-Lymphoma0low10
HTLV-III Infections0low20
HTLV-III-LAV Infections0low20
Human Flu0low10
Human Influenza0low10
Human Mammary Carcinoma0low40
Human Papillomavirus Infection0low20
Human T Lymphotropic Virus Associated Leukemia Lymphoma0low10
Human T Lymphotropic Virus-Associated Leukemia-Lymphoma0low10
Human T-Cell Leukemia-Lymphoma0low10
Hydrophobia0low10
Hyper IgD Syndrome0low10
Hyper-beta-Lipoproteinemia0low10
Hyper-IgD Syndrome0low10
Hyper-Low Density Lipoproteinemia0low10
Hyper-Low-Density-Lipoproteinemia0low10
Hyperbetalipoproteinemia0low10
Hypercholesteremia0low50
Hypercholesterolemia0low50
Hypercholesterolemia, Autosomal Dominant0low10
Hypercholesterolemia, Autosomal Dominant, Type B0low10
Hypercholesterolemia, Essential0low10
Hypercholesterolemia, Familial0low10
Hypercholesterolemic Xanthomatosis, Familial0low10
Hyperimmunoglobulinemia D0low10
Hyperimmunoglobulinemia D And Periodic Fever Syndrome0low10
Hyperlipoproteinemia Type 20low10
Hyperlipoproteinemia Type II0low10
Hyperlipoproteinemia Type IIa0low10
Hyperlipoproteinemia Type IIb0low10
Hyperlipoproteinemia, Type II0low10
Hyperlipoproteinemia, Type IIa0low10
Hypernephroma0low10
Hypertrophic Motor-Sensory Neuropathy-Spastic Paraplegia0medium32
Hypolipoproteinemia0low10
Hypolipoproteinemias0low10
Hypopharyngeal Squamous Cell Carcinoma0low10
Hypoprebetalipoproteinemia0low10
Hypoxemia0low10
Hypoxia0low10
Ichthyosis0low10
IDDM0low10
Idiopathic Proctocolitis0low10
Ileitis, Regional0low10
Ileitis, Terminal0low10
Ileocolitis0low10
Impaired Glucose Tolerance0low10
Infarction, Middle Cerebral Artery0low10
Infection, Bacterial0low10
Infections, Bacterial0low10
Infections, Coronavirus0low40
Infections, Listeria0low10
Infections, Mycobacterium0low10
Infections, Orthomyxoviridae0low10
Infections, Orthomyxovirus0low10
Infections, Picornaviridae0low10
Infections, Picornavirus0low10
Infections, Rhabdoviridae0low30
Inflammation0low250
Inflammation, Brain0low10
Inflammatory Bowel Disease 10low10
Inflammatory Bowel Disease, Ulcerative Colitis Type0low10
Influenza0low10
Influenza in Humans0low10
Influenza, Human0low10
Injuries, Spinal Cord0low10
Injury, Ischemia-Reperfusion0low20
Injury, Myocardial Reperfusion0low20
Injury, Reperfusion0low20
Innate Inflammatory Response0low250
Insulin Resistance0low10
Insulin Sensitivity0low10
Insulin-Dependent Diabetes Mellitus 10low10
Internal Carotid Artery Diseases0low10
Interstitial Cell Tumor0low30
Intracapillary Glomerulosclerosis0low10
Intracranial Astrocytoma0low20
Intracranial Neoplasms0low10
Intrauterine Growth Restriction0low10
Intrauterine Growth Retardation0low10
Invasiveness, Neoplasm0low10
Irritant Dermatitis0low10
Ischemia-Reperfusion Injury0low20
Juvenile Pilocytic Astrocytoma0low20
Juvenile-Onset Diabetes0low10
Kidney Cancer0low20
Kidney Neoplasms0low20
Kimmelstiel-Wilson Disease0low10
Kimmelstiel-Wilson Syndrome0low10
Koch's Disease0low10
Kochs Disease0low10
Laryngeal Squamous Cell Carcinoma0low10
Late Onset Alzheimer Disease0low60
LCAT Deficiency0low10
LCATA Deficiency0low10
LDL Receptor Disorder0low10
Lecithin Cholesterol Acyltransferase Deficiency0low10
Left Main Coronary Artery Disease0low20
Left Main Coronary Disease0low20
Left Main Disease0low20
Left Middle Cerebral Artery Infarction0low10
Lens Opacities0low60
Leucocythaemia0low10
Leucocythemia0low10
Leukemia0low10
Leukemia L 12100low10
Leukemia L12100low10
Leukemia Lymphoma, Adult T Cell0low10
Leukemia Lymphoma, T Cell, Acute, HTLV I Associated0low10
Leukemia P3880low30
Leukemia-Lymphoma, Adult T-Cell0low10
Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated0low10
Leukemia, Acute Lymphoblastic0low30
Leukemia, Acute Monocytic0low20
Leukemia, Acute Myelogenous0low10
Leukemia, Acute Myeloid0low10
Leukemia, Adult T-Cell0low10
Leukemia, Hairy Cell0low10
Leukemia, Lymphoblastic0low30
Leukemia, Lymphoblastic, Acute0low30
Leukemia, Lymphoblastic, Acute, L10low30
Leukemia, Lymphoblastic, Acute, L20low30
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive0low30
Leukemia, Lymphocytic0low10
Leukemia, Lymphocytic, Acute0low30
Leukemia, Lymphocytic, Acute, L10low30
Leukemia, Lymphocytic, Acute, L20low30
Leukemia, Lymphocytic, T Cell0low10
Leukemia, Lymphocytic, T-Cell0low10
Leukemia, Lymphoid0low10
Leukemia, Lymphoid, Acute0low30
Leukemia, Monoblastic, Acute0low20
Leukemia, Monocytic, Acute0low20
Leukemia, Myeloblastic, Acute0low10
Leukemia, Myelocytic, Acute0low10
Leukemia, Myelogenous, Acute0low10
Leukemia, Myeloid, Acute0low10
Leukemia, Myeloid, Acute, M10low10
Leukemia, Myeloid, Acute, M20low10
Leukemia, Myeloid, Acute, M50low20
Leukemia, Myeloid, Schilling Type0low20
Leukemia, Myeloid, Schilling-Type0low20
Leukemia, Nonlymphoblastic, Acute0low10
Leukemia, Nonlymphocytic, Acute0low10
Leukemia, T-Cell0low10
Leukemic Reticuloendotheliosis0low10
Leydig Cell Tumor0low30
Liposarcoma0low10
Liposarcoma, Dedifferentiated0low10
Liposarcoma, Pleomorphic0low10
Liposarcoma, Well Differentiated0low10
Listeria Infections0low10
Listeriosis0low10
Liver Cancer0low200
Liver Cancer, Adult0low210
Liver Cell Carcinoma0low210
Liver Cell Carcinoma, Adult0low210
Liver Diseases0low10
Liver Dysfunction0low10
Liver Neoplasms0low200
Liver Neoplasms, Experimental0low100
Lobar Pneumonia0low10
Lou Gehrig Disease0low20
Lou Gehrig's Disease0low20
Lou-Gehrigs Disease0low20
Lung Cancer0low20
Lung Inflammation0low10
Lung Injury, Acute0low20
Lung Neoplasms0low20
Lymphoblastic Leukemia0low30
Lymphoblastic Leukemia, Acute0low30
Lymphoblastic Leukemia, Acute, Adult0low30
Lymphoblastic Leukemia, Acute, Childhood0low30
Lymphoblastic Leukemia, Acute, L10low30
Lymphoblastic Leukemia, Acute, L20low30
Lymphoblastic Lymphoma0low30
Lymphocytic Leukemia0low10
Lymphocytic Leukemia, Acute0low30
Lymphocytic Leukemia, L10low30
Lymphocytic Leukemia, L20low30
Lymphocytic Leukemia, T-Cell0low10
Lymphoid Leukemia0low10
Lymphoma, Lymphoblastic0low30
Lyssa0low10
Macular Degeneration0low10
Macular Degeneration, Age-Related0low10
Macular Dystrophy0low10
Maculopathies, Age-Related0low10
Maculopathy0low10
Maculopathy, Age-Related0low10
Malignancy0low50
Malignant Glioma0low10
Malignant Melanoma0low10
Malignant Neoplasm of Breast0low40
Malignant Neoplasms0low50
Malignant Neoplasms, Brain0low10
Malignant Primary Brain Neoplasms0low10
Malignant Primary Brain Tumors0low10
Malignant Tumor of Breast0low40
Mammary Cancer0low40
Mammary Carcinoma, Human0low40
Mammary Neoplasm, Human0low40
Mammary Neoplasms, Experimental0low10
Mammary Neoplasms, Human0low40
Marasmus0low10
Marek Disease0low10
Marek's Disease0low10
Mast-Cell Sarcoma0low20
Mastocytoma, Malignant0low20
Maturity-Onset Diabetes0low10
Maturity-Onset Diabetes Mellitus0low10
MCA Infarct0low10
MCA Infarction0low10
Melanodermic Leukodystrophy0low10
Melanoma0low10
MERS (Middle East Respiratory Syndrome)0low40
Metastase0low10
Metastases, Neoplasm0low10
Metastasis0low10
Metastasis, Neoplasm0low10
Mevalonate Kinase Deficiency0low10
Mevalonic Aciduria0low10
Mevalonicaciduria0low10
Microcalcification0low10
Microcalcinosis0low10
Microcephaly0low10
Microlissencephaly0low10
Middle Cerebral Artery Circulation Infarction0low10
Middle Cerebral Artery Embolic Infarction0low10
Middle Cerebral Artery Embolus0low10
Middle Cerebral Artery Infarction0low10
Middle Cerebral Artery Occlusion0low10
Middle Cerebral Artery Stroke0low10
Middle Cerebral Artery Syndrome0low10
Middle Cerebral Artery Thrombosis0low10
Middle Cerebral Artery Thrombotic Infarction0low10
Middle East Respiratory Syndrome0low40
Mixed Glioma0low10
MODY0low10
Monoblastic Leukemia, Acute0low20
Monocytic Leukemia, Acute0low20
Motor Neuron Disease, Amyotrophic Lateral Sclerosis0low20
MS (Multiple Sclerosis)0low20
Multiple Sclerosis0low20
Multiple Sclerosis, Acute Fulminating0low20
Muscular Atrophy0low10
Mycobacterium Infections0low10
Mycobacterium tuberculosis Infection0low10
Myeloblastic Leukemia, Acute0low10
Myelocytic Leukemia, Acute0low10
Myelogenous Leukemia, Acute0low10
Myeloid Leukemia, Acute0low10
Myeloid Leukemia, Acute, M10low10
Myeloid Leukemia, Acute, M20low10
Myeloid Leukemia, Acute, M50low20
Myeloid Leukemia, Schilling-Type0low20
Myelopathy, Traumatic0low10
Myocardial Ischemic Reperfusion Injury0low20
Myocardial Preinfarction Syndrome0low10
Myocardial Reperfusion Injury0low20
Mystery Swine Disease0low20
NAFLD0low20
Necrosis0low30
Neoplasia0low50
Neoplasm0low50
Neoplasm Invasion0low10
Neoplasm Invasiveness0low10
Neoplasm Metastases0low10
Neoplasm Metastasis0low10
Neoplasms0low50
Neoplasms, Adrenal Cortex0low20
Neoplasms, Benign0low50
Neoplasms, Brain0low10
Neoplasms, Brain, Benign0low10
Neoplasms, Brain, Malignant0low10
Neoplasms, Brain, Primary0low10
Neoplasms, Breast0low40
Neoplasms, Cervical0low20
Neoplasms, Cervix0low20
Neoplasms, Colonic0low30
Neoplasms, Colorectal0low20
Neoplasms, Epithelial0low10
Neoplasms, Experimental0low10
Neoplasms, Experimental Liver0low100
Neoplasms, Experimental Mammary0low10
Neoplasms, Gastric0low10
Neoplasms, Glandular0low10
Neoplasms, Glandular and Epithelial0low10
Neoplasms, Glandular Epithelial0low10
Neoplasms, Hepatic0low200
Neoplasms, Hormone-Dependent0low10
Neoplasms, Intracranial0low10
Neoplasms, Kidney0low20
Neoplasms, Liver0low200
Neoplasms, Lung0low20
Neoplasms, Ovarian0low20
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Neoplasms, Pulmonary0low20
Neoplasms, Skin0low10
Neoplasms, Stomach0low10
Neoplastic Cell Transformation0low20
Neoplastic Transformation, Cell0low20
Nephroid Carcinoma0low10
Nervous System Degenerative Diseases0low20
Neuroblastoma0low30
Neurodegenerative Diseases0low20
Neurodegenerative Disorders0low20
Neurogenic Muscular Atrophy0low10
Neurologic Degenerative Conditions0low20
Neurologic Degenerative Diseases0low20
Neurologic Diseases, Degenerative0low20
Neurotrophic Muscular Atrophy0low10
Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia0low40
NIDDM0low10
Niemann-Pick Disease0low100
Niemann-Pick Disease Type C0low40
Niemann-Pick Disease Type D0low40
Niemann-Pick Disease with Cholesterol Esterification Block0low40
Niemann-Pick Disease without Sphingomyelinase Deficiency0low40
Niemann-Pick Disease, Chronic Neuronopathic Form0low40
Niemann-Pick Disease, Nova Scotian0low40
Niemann-Pick disease, Subacute Juvenile Form0low40
Niemann-Pick Disease, Type C0low40
Niemann-Pick Disease, Type C10low40
Niemann-Pick Disease, Type D0low40
Niemann-Pick Diseases0low100
Niemann-Pick Type C Disease0low40
Niemann-Pick Type D Disease0low40
Niemann-Pick's Disease Type C0low40
Niemann-Pick's Disease Type D0low40
Nodular Glomerulosclerosis0low10
Non-alcoholic Fatty Liver Disease0low20
Non-Small Cell Lung Cancer0low10
Non-Small Cell Lung Carcinoma0low10
Non-Small-Cell Lung Carcinoma0low10
Nonalcoholic Fatty Liver Disease0low20
Nonalcoholic Steatohepatitis0low20
Noninsulin-Dependent Diabetes Mellitus0low10
Nonlymphoblastic Leukemia, Acute0low10
Nonlymphocytic Leukemia, Acute0low10
Nonsmall Cell Lung Cancer0low10
Norum Disease0low10
Nova Scotia (Type D) Form of Niemann-Pick Disease0low40
Nova Scotia Niemann-Pick Disease (Type D)0low40
Occlusion, Middle Cerebral Artery0low10
Oesophageal Squamous Cell Carcinoma0low10
Oligoastrocytoma, Mixed0low20
Oral Cavity Squamous Cell Carcinoma0low10
Oral Squamous Cell Carcinoma0low10
Oral Squamous Cell Carcinomas0low10
Oral Tongue Squamous Cell Carcinoma0low10
Oropharyngeal Squamous Cell Carcinoma0low10
Orthomyxoviridae Infections0low10
Orthomyxovirus Infections0low10
Osteoarthritis0low10
Osteoarthrosis0low10
Osteoarthrosis Deformans0low10
Osteoclastic Bone Loss0low10
Ovarian Cancer0low20
Ovarian Cancer, Epithelial0low10
Ovarian Epithelial Cancer0low10
Ovarian Epithelial Carcinoma0low10
Ovarian Neoplasms0low20
Ovary Cancer0low20
Ovary Neoplasms0low20
Oxygen Deficiency0low10
P388D(1) Leukemia0low30
Papillary Renal Cell Carcinoma0low10
Papillomavirus Infections0low20
Pappataci Fever0low10
Paralysis, Legs0low10
Paralysis, Lower Extremities0low10
Paralysis, Lower Limbs0low10
Paraplegia0low10
Paraplegia, Ataxic0low10
Paraplegia, Cerebral0low10
Paraplegia, Flaccid0low10
Paraplegia, Spastic0low10
Paraplegia, Spastic, Hereditary0medium32
Paraplegia, Spinal0low10
Parenterally-Transmitted Non-A, Non-B Hepatitis0low20
Paroxysmal Atrial Fibrillation0low10
Pathologic Calcification0low10
Periodic Fever, Dutch Type0low10
Peripheral Arterial Disease0low10
Peripheral Arterial Diseases0low10
Peripheral Artery Disease0low10
Peroneal Muscular Atrophy with Pyramidal Features, Autosomal Dominant0medium32
Persistent Atrial Fibrillation0low10
Phlebotomus Fever0low10
Photodermatitis0low10
Photosensitivity Disorders0low10
Photosensitization0low10
Picornaviridae Infections0low10
Picornavirus Infections0low10
Pilocytic Astrocytoma0low20
Plaque, Atherosclerotic0low40
Pneumonia0low10
Pneumonia, Lobar0low10
Pneumonia, Viral0low10
Pneumonitis0low10
Porcine Epidemic Abortion and Respiratory Syndrome0low20
Porcine Reproductive and Respiratory Syndrome0low20
Post-Traumatic Myelopathy0low10
Poultry Diseases0low10
Precursor Cell Lymphoblastic Leukemia-Lymphoma0low30
Predisposition, Genetic0low10
Pregnancy0low170
Presenile Alzheimer Dementia0low60
Primary Brain Neoplasms0low10
Primary Malignant Brain Neoplasms0low10
Primary Malignant Brain Tumors0low10
Primary Senile Degenerative Dementia0low60
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Cancer0low20
Prostatic Neoplasms0low20
Protein Aggregation, Pathological0low20
Protein Deficiency0low10
Protein-Calorie Malnutrition0low10
Protein-Energy Malnutrition0low10
PRRS0low20
Pseudoaphakia0low60
PT-NANBH0low20
Pulmonary Cancer0low20
Pulmonary Disease, Chronic Obstructive0low10
Pulmonary Inflammation0low10
Pulmonary Neoplasms0low20
Rabies0low10
Rasmussen Encephalitis0low10
Rasmussen Syndrome0low10
Rasmussen's Syndrome0low10
Reaction, Acute-Phase0low10
Regional Enteritis0low10
Renal Cancer0low20
Renal Carcinoma0low10
Renal Cell Cancer0low10
Renal Cell Carcinoma0low10
Renal Cell Carcinoma, Papillary0low10
Renal Collecting Duct Carcinoma0low10
Renal Neoplasms0low20
Reperfusion Damage0low20
Reperfusion Injury0low20
Reperfusion Injury, Myocardial0low20
Response, Acute-Phase0low10
Reticuloendotheliosis, Leukemic0low10
Rhabdoviridae Infections0low30
Right Middle Cerebral Artery Infarction0low10
Rotavirus Infections0low20
SAIDS0low10
Sandfly Fever0low10
Sarcoma, Mast-Cell0low20
Sarcomatoid Renal Cell Carcinoma0low10
SARS Coronavirus 2 Infection0low60
SARS-CoV-2 Infection0low60
Schilder-Addison Complex0low10
Sclerosis, Disseminated0low20
Senile Dementia, Acute Confusional0low60
Senile Dementia, Alzheimer Type0low60
Sensitivity and Specificity0low10
Septic Shock0low10
Severe Congenital Microcephaly0low10
Shock, Endotoxic0low10
Shock, Septic0low10
Shock, Toxic0low10
Siemerling-Creutzfeldt Disease0low10
Simian Acquired Immune Deficiency Syndrome0low10
Simian Acquired Immuno-Deficiency Syndrome0low10
Simian Acquired Immunodeficiency Syndrome0low10
Simian AIDS0low10
Skin Aging0low10
Skin Cancer0low10
Skin Neoplasms0low10
Spastic Paraplegia0low10
Spastic Paraplegia 20medium32
Spastic Paraplegia Type 20medium32
Spastic Paraplegia-Hypertrophic Motor-Sensory Neuropathy0medium32
Spastic Paraplegia, Autosomal Dominant, Hereditary0medium32
Spastic Paraplegia, Autosomal Recessive, Hereditary0medium32
Spastic Paraplegia, Hereditary0medium32
Spastic Paraplegia, Hereditary, Autosomal Dominant0medium32
Spastic Paraplegia, Hereditary, Autosomal Recessive0medium32
Spastic Paraplegia, Hereditary, X-Linked Recessive0medium32
Spastic Paraplegia, X-Linked Recessive, Hereditary0medium32
Spinal Cord Contusion0low10
Spinal Cord Injuries0low10
Spinal Cord Laceration0low10
Spinal Cord Transection0low10
Spinal Cord Trauma0low10
Squamous Cell Carcinoma0low10
Squamous Cell Carcinoma of Head and Neck0low10
Squamous Cell Carcinoma of Larynx0low10
Squamous Cell Carcinoma of the Head and Neck0low10
Squamous Cell Carcinoma of the Larynx0low10
Squamous Cell Carcinoma of the Mouth0low10
Squamous Cell Carcinoma of the Nasal Cavity0low10
Squamous Cell Carcinoma, Head And Neck0low10
Stenocardia0low10
Stomach Cancer0low10
Stomach Neoplasms0low10
Stroke, Middle Cerebral Artery0low10
Subependymal Giant Cell Astrocytoma0low20
Susceptibility, Disease0low10
Susceptibility, Genetic0low10
Swine Diseases0low20
Swine Fever0low10
Swine Fever, African0low10
Swine Fever, Classical0low10
Swine Infertility and Respiratory Syndrome0low20
Swine Influenza0low10
T Cell Leukemia Lymphoma, HTLV I Associated0low10
T Cell Leukemia, Adult0low10
T Lymphocytic Leukemia0low10
T-Cell Leukemia0low10
T-Cell Leukemia-Lymphoma, Adult0low10
T-Cell Leukemia-Lymphoma, HTLV-I-Associated0low10
T-Cell Leukemia, Adult0low10
T-Lymphocytic Leukemia0low10
T-Lymphotropic Virus Type III Infections, Human0low20
Thoracoabdominal Aortic Aneurysm0low10
Thrombocytopenia0low10
Thrombopenia0low10
Thrombosis, Middle Cerebral Artery0low10
Thrombotic Infarction, Middle Cerebral Artery0low10
Thymoma0low10
Toxic Shock0low10
Toxic Shock Syndrome0low10
Transformation, Neoplastic Cell0low20
Transformation, Viral Cell0low30
Tuberculosis0low10
Tumorigenic Transformation0low20
Tumors0low50
Tumors, Breast0low40
Type 1 Diabetes0low10
Type 1 Diabetes Mellitus0low10
Type 2 Diabetes0low10
Type 2 Diabetes Mellitus0low10
Type V Hereditary Motor and Sensory Neuropathy0medium32
Ulcerative Colitis0low10
Unstable Angina0low10
Uterine Cervical Cancer0low20
Uterine Cervical Neoplasms0low20
Van Bogaert-Scherer-Epstein Disease0low10
Vascular Calcification0low20
Vascular Calcinosis0low20
Viral Cell Transformation0low30
Viral Diseases0low20
Viral Infections0low20
Viremia0low10
Virus Diseases0low20
Virus Infections0low20
Wart-Hog Disease0low10
Well Differentiated Liposarcoma0low10
X Linked Recessive Hereditary Spastic Paraplegia0medium32
X-ALD0low10
X-ALD (X-Linked Adrenoleukodystrophy)0low10
X-Linked Adrenoleukodystrophy0low10
X-linked Recessive Hereditary Spastic Paraplegia0medium32
X-Linked, Spastic Paraplegia, Hereditary0medium32
Xanthomatosis, Cerebrotendinous0low10
Xeroderma0low10
Zika Fever0low20
Zika Virus Disease0low20
Zika Virus Infection0low20
ZikV Infection0low20

Research Highlights

Safety/Toxicity (15)

ArticleYear
Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Volume: 33, Issue: 4		2019
Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol.
Journal of lipid research, Volume: 57, Issue: 10		2016
Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells.
Current eye research, Volume: 38, Issue: 11		2013
Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity.
Biochimica et biophysica acta, Volume: 1801, Issue: 9		2010
Oxysterol-induced toxicity in R28 and ARPE-19 cells.
Neurochemical research, Volume: 28, Issue: 6		2003
Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: modulatory effects of phytochemicals.
Biochemical Society transactions, Volume: 28, Issue: 2		2000
Neurotoxicity of cholesterol oxides on cultured cerebellar granule cells.
Neurochemistry international, Volume: 32, Issue: 4		1998
Neurotoxicity of 25-OH-cholesterol on sympathetic neurons.
Brain research bulletin, Volume: 45, Issue: 6		1998
Neurotoxicity of 25-OH-cholesterol on NGF-differentiated PC12 cells.
Neurochemical research, Volume: 23, Issue: 1		1998
Lipoprotein-like phospholipid particles inhibit the smooth muscle cell cytotoxicity of lysophosphatidylcholine and platelet-activating factor.
Arteriosclerosis, thrombosis, and vascular biology, Volume: 18, Issue: 1		1998
Cytotoxicity of oxysterols on cultured smooth muscle cells from human umbilical arteries.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), Volume: 202, Issue: 1		1993
Cytotoxicity of cholesterol oxides and their effects on cholesterol metabolism in cultured human aortic smooth muscle cells.
Biochemistry international, Volume: 14, Issue: 1		1987
Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region.
The American journal of pathology, Volume: 137, Issue: 2		1990
Inhibitors of protein and RNA synthesis block the cytotoxic effects of oxygenated sterols.
Biochimica et biophysica acta, Jul-22, Volume: 1136, Issue: 1		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (2)

ArticleYear
Early differences in membrane properties at the neuromuscular junctions of ALS model mice: Effects of 25-hydroxycholesterol.
Life sciences, May-15, Volume: 273		2021
In vitro binding and utilization of lipoproteins by luteal cells from ferrets treated with dopaminergic drugs during pseudopregnancy.
General and comparative endocrinology, Volume: 67, Issue: 3		1987
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (6)

ArticleYear
Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes (Danio rerio).
Aquatic toxicology (Amsterdam, Netherlands), Volume: 198		2018
Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells.
Gynecologic oncology, Volume: 135, Issue: 2		2014
25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells.
Journal of lipid research, Volume: 36, Issue: 6		1995
Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced cholesterol ac
The Journal of biological chemistry, Mar-05, Volume: 261, Issue: 7		1986
The interaction of hCG, hydroxysteroids and interstitial fluid on rat Leydig cell steroidogenesis in vitro.
Journal of reproduction and fertility, Volume: 77, Issue: 1		1986
Modifications of cellular lipids induce insulin resistance in cultured hepatoma cells.
Biochimica et biophysica acta, May-18, Volume: 928, Issue: 3		1987
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]