papaverine has been researched along with Sensitivity and Specificity in 32 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A total of 400 patients with erectile dysfunction were evaluated before and after diagnostic intracavernous injection of a trimix solution (papaverine+phentolamine+PGE1) using color Doppler sonography." | 5.11 | The value of penile duplex in the prediction of intracavernous drug-induced priapism. ( Ghanem, HM; Kamel, II; Mousa, AA; Salem, A; Shamloul, R, 2004) |
| "This study sought to elucidate serial changes in microvascular integrity during papaverine-induced hyperemia in the risk area for myocardial infarction." | 3.71 | Optimal time for predicting myocardial viability after successful primary angioplasty in acute myocardial infarction: a study using myocardial contrast echocardiography. ( Fujiwara, H; Hayashi, Y; Imazu, M; Okimoto, T; Otsuka, M; Sakuma, T; Sumii, K, 2001) |
| "Hyperemia was induced by administration of intrarenal papavarine." | 1.33 | Renal fractional flow reserve: a hemodynamic evaluation of moderate renal artery stenoses. ( Almagor, Y; Bashir, R; Meerkin, D; Rosenfield, K; Shalman, E; Subramanian, R; White, CJ, 2005) |
| "Hyperemia is unnecessary and not useful for predicting > 50% stenosis." | 1.29 | Analysis and comparison of pressure gradients and ratios for predicting iliac stenosis. ( Archie, JP, 1994) |
| "Sensitivity and specificity were calculated for each side separately." | 1.29 | [A comparison of color duplex sonography with selective penile DSA in assessing erectile dysfunction]. ( Bautz, W; Brandstetter, K; Lenz, M; Pickl, U; Schwarzer, JU, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 17 (53.13) | 29.6817 |
| 2010's | 4 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shiode, N | 1 |
| Okimoto, T | 2 |
| Tamekiyo, H | 1 |
| Kawase, T | 1 |
| Yamane, K | 1 |
| Kagawa, Y | 1 |
| Fujii, Y | 1 |
| Ueda, Y | 1 |
| Hironobe, N | 1 |
| Kato, Y | 1 |
| Hayashi, Y | 2 |
| Vancea, S | 1 |
| Gáll, Z | 1 |
| Donáth-Nagy, G | 1 |
| Borka-Balás, R | 1 |
| Gu, P | 1 |
| Ding, Y | 1 |
| Sun, D | 1 |
| Hang, T | 1 |
| Liu, W | 1 |
| Ding, L | 1 |
| Kahvecioğlu, N | 1 |
| Kurt, A | 1 |
| Ipek, A | 1 |
| Yazicioğlu, KR | 1 |
| Akbulut, Z | 1 |
| Dahivelkar, PP | 1 |
| Bhoir, SI | 1 |
| Bari, SB | 1 |
| Surana, SJ | 1 |
| Bhagwat, AM | 1 |
| Frydrychowski, AF | 1 |
| Gumiński, W | 1 |
| Rojewski, M | 1 |
| Kaczmarek, J | 1 |
| Juzwa, W | 1 |
| Zhuang, YF | 1 |
| Zhang, SC | 1 |
| Yu, JS | 1 |
| Ju, HX | 1 |
| El-Gindy, A | 2 |
| Emara, S | 1 |
| Hadad, GM | 1 |
| Shamloul, R | 2 |
| Ghanem, HM | 2 |
| Salem, A | 2 |
| Kamel, II | 1 |
| Mousa, AA | 2 |
| Elnashaar, A | 1 |
| Elnaggar, W | 1 |
| Darwish, H | 1 |
| Subramanian, R | 1 |
| White, CJ | 1 |
| Rosenfield, K | 1 |
| Bashir, R | 1 |
| Almagor, Y | 1 |
| Meerkin, D | 1 |
| Shalman, E | 1 |
| Kharitonov, SV | 1 |
| El-Saharty, YS | 1 |
| Metwaly, FH | 1 |
| Refaat, M | 1 |
| El-Khateeb, SZ | 1 |
| Amin, AS | 1 |
| El-Sheikh, R | 1 |
| Zahran, F | 1 |
| Gouda, AA | 1 |
| Liang, C | 1 |
| Zhang, YR | 1 |
| Jin, QY | 1 |
| Guo, YM | 1 |
| Lin, X | 1 |
| Wang, J | 1 |
| Li, L | 1 |
| Wang, X | 1 |
| Lü, H | 1 |
| Xie, Z | 1 |
| Boca, P | 1 |
| Brenner, N | 1 |
| Andrianne, R | 1 |
| Archie, JP | 1 |
| Alós, R | 1 |
| Garcia-Granero, E | 1 |
| Calvete, J | 1 |
| Uribe, N | 1 |
| Brandstetter, K | 1 |
| Schwarzer, JU | 1 |
| Bautz, W | 1 |
| Pickl, U | 1 |
| Lenz, M | 1 |
| Zuckier, LS | 1 |
| Korupolu, GR | 1 |
| Gladshteyn, M | 1 |
| Sattenberg, R | 1 |
| Goldstein, R | 1 |
| Ricciardi, R | 1 |
| Goodwin, P | 1 |
| Melman, A | 1 |
| Blaufox, MD | 1 |
| Karadeniz, T | 1 |
| Ariman, A | 1 |
| Topsakal, M | 1 |
| Eksioglu, A | 1 |
| Engin, T | 1 |
| Basak, D | 1 |
| Illig, KA | 1 |
| Ouriel, K | 1 |
| DeWeese, JA | 1 |
| Riggs, P | 1 |
| Green, RM | 1 |
| Hatzichristou, DG | 1 |
| Hatzimouratidis, K | 1 |
| Apostolidis, A | 1 |
| Ioannidis, E | 1 |
| Yannakoyorgos, K | 1 |
| Kalinderis, A | 1 |
| Sakuma, T | 1 |
| Otsuka, M | 1 |
| Fujiwara, H | 1 |
| Sumii, K | 1 |
| Imazu, M | 1 |
| Mallet, CR | 1 |
| Mazzeo, JR | 1 |
| Neue, U | 1 |
| Arslan, D | 1 |
| Esen, AA | 1 |
| Seçil, M | 1 |
| Aslan, G | 1 |
| Celebi, I | 1 |
| Dicle, O | 1 |
| Bogusz, MJ | 1 |
| Maier, RD | 1 |
| Erkens, M | 1 |
| Kohls, U | 1 |
| Casabe, A | 1 |
| Bechara, A | 1 |
| Wizenberg, P | 1 |
| D'Osvaldo, C | 1 |
| Rovegno, A | 1 |
| Fernández, H | 1 |
| Mocellini Iturralde, J | 1 |
| Wilson, RF | 1 |
| Marcus, ML | 1 |
| Christensen, BV | 1 |
| Talman, C | 1 |
| White, CW | 1 |
| Liu, LC | 1 |
| Wu, CC | 1 |
| Liu, LH | 1 |
| Chiang, CP | 1 |
| Huang, CH | 1 |
| Chou, YH | 1 |
| Tan, LB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient[NCT02387658] | 25 participants (Actual) | Observational | 2015-02-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for papaverine and Sensitivity and Specificity
| Article | Year |
|---|---|
The value of penile duplex in the prediction of intracavernous drug-induced priapism.
Topics: Alprostadil; Antihypertensive Agents; Erectile Dysfunction; Humans; Ischemia; Male; Middle Aged; Pap | 2004 |
Hemodynamic characterization of a functional erection. Arterial and corporeal veno-occlusive function in patients with a positive intracavernosal injection test.
Topics: Adult; Alprostadil; Constriction, Pathologic; Erectile Dysfunction; Hemodynamics; Humans; Impotence, | 1999 |
A new method for the evaluation of erectile dysfunction: sildenafil plus Doppler ultrasonography.
Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Erectile Dysfunction; Humans; Image Enhancem | 2001 |
29 other studies available for papaverine and Sensitivity and Specificity
| Article | Year |
|---|---|
A Comparison between the Instantaneous Wave-free Ratio and Resting Distal Coronary Artery Pressure/Aortic Pressure and the Fractional Flow Reserve: The Diagnostic Accuracy Can Be Improved by the Use of both Indices.
Topics: Aged; Aorta; Arterial Pressure; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Fe | 2017 |
Rapid LC-MS/MS method for determination of drotaverine in a bioequivalence study.
Topics: Chromatography, Liquid; Humans; Imipramine; Methanol; Papaverine; Plasma; Reference Standards; Repro | 2014 |
Quantification of henatinib maleate, a novel potent inhibitor of VEGF receptors, in rat plasma by LC-MS/MS.
Topics: Animals; Antineoplastic Agents; Azepines; Chromatography, High Pressure Liquid; Drug Stability; Fema | 2010 |
Predictive value of cavernosal peak systolic velocity in the flaccid penis.
Topics: Adult; Aged; Arteries; Blood Flow Velocity; Diabetes Mellitus, Type 2; Diagnosis, Differential; Erec | 2009 |
Simultaneous determination of diclofenac potassium and drotaverine hydrochloride in human plasma using reversed-phase high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diclofenac; Humans; Least-Squar | 2012 |
Technical foundations for noninvasive assessment of changes in the width of the subarachnoid space with near-infrared transillumination-backscattering sounding (NIR-TBSS).
Topics: Algorithms; Animals; Cerebrovascular Circulation; Head; Heart Rate; Humans; Hypercapnia; Hypoxia; Li | 2002 |
Flow injection determination of papaverine based on its sensitizing effect on the chemiluminescence reaction of permanganate-sulfite.
Topics: Flow Injection Analysis; Kinetics; Luminescent Measurements; Manganese Compounds; Oxides; Papaverine | 2003 |
Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Mephobarbital; Papaverine; Phenobarbital; Phe | 2003 |
Correlation between penile duplex findings and stress electrocardiography in men with erectile dysfunction.
Topics: Adrenergic alpha-Antagonists; Adult; Coronary Disease; Echocardiography, Stress; Humans; Impotence, | 2004 |
Renal fractional flow reserve: a hemodynamic evaluation of moderate renal artery stenoses.
Topics: Aged; Angiography; Cohort Studies; Female; Hemodynamics; Humans; Hyperemia; Linear Models; Male; Mid | 2005 |
Transport properties and electroanalytical response characteristics of drotaverine ion-selective sensors.
Topics: Calibration; Electrochemistry; Ion-Selective Electrodes; Membranes, Artificial; Papaverine; Parasymp | 2005 |
HPLC and chemometric assisted spectrophotometric methods for simultaneous determination of diprophylline, phenobarbitone and papaverine hydrochloride.
Topics: Bronchodilator Agents; Chromatography, High Pressure Liquid; Dyphylline; Papaverine; Pharmaceutical | 2005 |
Application of new membrane selective electrodes for the determination of drotaverine hydrochloride in tablets and plasma.
Topics: Calibration; Electrodes; Humans; Papaverine; Parasympatholytics; Sensitivity and Specificity; Tablet | 2006 |
Spectrophotometric determination of pipazethate HCl, dextromethorphan HBr and drotaverine HCl in their pharmaceutical preparations.
Topics: Antitussive Agents; Benzothiadiazines; Calibration; Chloroform; Dextromethorphan; Dose-Response Rela | 2007 |
[Analysis of 37 drugs in whole blood by HPLC after solid phase extraction].
Topics: Chromatography, High Pressure Liquid; Doxapram; Doxepin; Estazolam; Forensic Medicine; Humans; Morph | 2006 |
Separation and determination of five major opium alkaloids with mixed mode of hydrophilic/cation-exchange monolith by pressurized capillary electrochromatography.
Topics: Capillary Electrochromatography; Cations; Codeine; Ion Exchange; Molecular Conformation; Morphine; N | 2007 |
[Efficacy of Doppler color echography in the diagnosis of caverno-venous leakage in the impotent patient].
Topics: Arteries; Humans; Impotence, Vasculogenic; Male; Papaverine; Penis; Retrospective Studies; Sensitivi | 1995 |
Analysis and comparison of pressure gradients and ratios for predicting iliac stenosis.
Topics: Arterial Occlusive Diseases; Blood Pressure; Constriction, Pathologic; Femoral Artery; Forecasting; | 1994 |
The use of photoplethysmography and Doppler ultrasound to predict anastomotic viability after segmental intestinal ischaemia in dogs.
Topics: Anastomosis, Surgical; Animals; Arteries; Dogs; Ileum; Injections, Intra-Arterial; Ischemia; Jejunum | 1993 |
[A comparison of color duplex sonography with selective penile DSA in assessing erectile dysfunction].
Topics: Adult; Aged; Angiography, Digital Subtraction; Color; Erectile Dysfunction; Evaluation Studies as To | 1993 |
A nonimaging scintillation probe to measure penile hemodynamics.
Topics: Adult; Erythrocytes; Feasibility Studies; Humans; Impotence, Vasculogenic; Male; Papaverine; Penile | 1995 |
Value of color Doppler sonography in the diagnosis of venous impotence.
Topics: Adult; Aged; Humans; Impotence, Vasculogenic; Male; Middle Aged; Papaverine; Penile Erection; Predic | 1995 |
Increasing the sensitivity of the diagnosis of chronic venous obstruction.
Topics: Adult; Blood Vessel Prosthesis; Female; Femoral Vein; Humans; Iliac Vein; Papaverine; Polytetrafluor | 1996 |
Optimal time for predicting myocardial viability after successful primary angioplasty in acute myocardial infarction: a study using myocardial contrast echocardiography.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Circulation; Echoc | 2001 |
Evaluation of several solid phase extraction liquid chromatography/tandem mass spectrometry on-line configurations for high-throughput analysis of acidic and basic drugs in rat plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Clemastine; Diflunisal; Equipment Design; Indicators | 2001 |
Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Topics: Adult; Biomarkers; Chromatography, Liquid; Codeine; Drug Prescriptions; Heroin; Heroin Dependence; H | 2001 |
[Test with vasoactive drugs: its predictive value in the diagnosis of erectile sexual dysfunction of venous origin].
Topics: Adult; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penis; Phentolamine; Predi | 1992 |
Accuracy of exercise electrocardiography in detecting physiologically significant coronary arterial lesions.
Topics: Cardiac Output; Confidence Intervals; Coronary Angiography; Coronary Circulation; Coronary Disease; | 1991 |
Comparison of the effects of papaverine versus prostaglandin E1 on penile blood flow by color duplex sonography.
Topics: Alprostadil; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penis; Regional Blood Flow | 1991 |