[no definition available]
5-HT-4;
5-HT4;
Serotonin receptor 4
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 4-nonylphenol | Cavia porcellus (domestic guinea pig) | IC50 | 2.5710 | 1 | 0 |
| 4-nonylphenol | Cavia porcellus (domestic guinea pig) | Ki | 1.3470 | 1 | 0 |
| amiodarone | Cavia porcellus (domestic guinea pig) | IC50 | 0.4040 | 1 | 0 |
| amiodarone | Cavia porcellus (domestic guinea pig) | Ki | 0.2120 | 1 | 0 |
| amitriptyline | Cavia porcellus (domestic guinea pig) | IC50 | 0.0060 | 1 | 0 |
| amitriptyline | Cavia porcellus (domestic guinea pig) | Ki | 0.0032 | 1 | 0 |
| amoxapine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0038 | 1 | 0 |
| amoxapine | Cavia porcellus (domestic guinea pig) | Ki | 0.0020 | 1 | 0 |
| astemizole | Cavia porcellus (domestic guinea pig) | IC50 | 0.1790 | 1 | 0 |
| astemizole | Cavia porcellus (domestic guinea pig) | Ki | 0.0940 | 1 | 0 |
| bithionol | Cavia porcellus (domestic guinea pig) | IC50 | 8.7800 | 1 | 0 |
| bithionol | Cavia porcellus (domestic guinea pig) | Ki | 4.5990 | 1 | 0 |
| verapamil | Cavia porcellus (domestic guinea pig) | IC50 | 0.2970 | 1 | 0 |
| verapamil | Cavia porcellus (domestic guinea pig) | Ki | 0.1550 | 1 | 0 |
| carvedilol | Cavia porcellus (domestic guinea pig) | IC50 | 0.1150 | 1 | 0 |
| carvedilol | Cavia porcellus (domestic guinea pig) | Ki | 0.0600 | 1 | 0 |
| chlorpromazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0052 | 1 | 0 |
| chlorpromazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0027 | 1 | 0 |
| cisapride | Cavia porcellus (domestic guinea pig) | IC50 | 0.7670 | 1 | 0 |
| cisapride | Cavia porcellus (domestic guinea pig) | Ki | 0.1148 | 4 | 3 |
| citalopram | Cavia porcellus (domestic guinea pig) | IC50 | 0.2970 | 1 | 0 |
| citalopram | Cavia porcellus (domestic guinea pig) | Ki | 0.1560 | 1 | 0 |
| clomipramine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0340 | 1 | 0 |
| clomipramine | Cavia porcellus (domestic guinea pig) | Ki | 0.0180 | 1 | 0 |
| clotrimazole | Cavia porcellus (domestic guinea pig) | IC50 | 14.4720 | 1 | 0 |
| clotrimazole | Cavia porcellus (domestic guinea pig) | Ki | 7.5810 | 1 | 0 |
| cyproheptadine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0024 | 1 | 0 |
| cyproheptadine | Cavia porcellus (domestic guinea pig) | Ki | 0.0013 | 1 | 0 |
| dicyclomine | Cavia porcellus (domestic guinea pig) | IC50 | 0.4680 | 1 | 0 |
| dicyclomine | Cavia porcellus (domestic guinea pig) | Ki | 0.2450 | 1 | 0 |
| diphenhydramine | Cavia porcellus (domestic guinea pig) | IC50 | 0.9800 | 1 | 0 |
| diphenhydramine | Cavia porcellus (domestic guinea pig) | Ki | 0.5130 | 1 | 0 |
| domperidone | Cavia porcellus (domestic guinea pig) | IC50 | 1.3320 | 1 | 0 |
| domperidone | Cavia porcellus (domestic guinea pig) | Ki | 0.6980 | 1 | 0 |
| doxazosin | Cavia porcellus (domestic guinea pig) | IC50 | 0.5440 | 1 | 0 |
| doxazosin | Cavia porcellus (domestic guinea pig) | Ki | 0.2850 | 1 | 0 |
| doxepin | Cavia porcellus (domestic guinea pig) | IC50 | 0.0460 | 1 | 0 |
| doxepin | Cavia porcellus (domestic guinea pig) | Ki | 0.0240 | 1 | 0 |
| droperidol | Cavia porcellus (domestic guinea pig) | IC50 | 0.4540 | 1 | 0 |
| droperidol | Cavia porcellus (domestic guinea pig) | Ki | 0.2380 | 1 | 0 |
| ebastine | Cavia porcellus (domestic guinea pig) | IC50 | 0.2375 | 1 | 0 |
| ebastine | Cavia porcellus (domestic guinea pig) | Ki | 0.1244 | 1 | 0 |
| econazole | Cavia porcellus (domestic guinea pig) | IC50 | 11.9820 | 1 | 0 |
| econazole | Cavia porcellus (domestic guinea pig) | Ki | 6.2760 | 1 | 0 |
| fenofibrate | Cavia porcellus (domestic guinea pig) | IC50 | 2.3710 | 1 | 0 |
| fenofibrate | Cavia porcellus (domestic guinea pig) | Ki | 1.2420 | 1 | 0 |
| fluphenazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0670 | 1 | 0 |
| fluphenazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0350 | 1 | 0 |
| fluoxetine | Cavia porcellus (domestic guinea pig) | IC50 | 0.1095 | 2 | 1 |
| fluoxetine | Cavia porcellus (domestic guinea pig) | Ki | 0.0620 | 1 | 0 |
| guanfacine | Cavia porcellus (domestic guinea pig) | IC50 | 1.4530 | 1 | 0 |
| guanfacine | Cavia porcellus (domestic guinea pig) | Ki | 0.7610 | 1 | 0 |
| haloperidol | Cavia porcellus (domestic guinea pig) | IC50 | 1.6765 | 2 | 1 |
| haloperidol | Cavia porcellus (domestic guinea pig) | Ki | 2.1324 | 2 | 1 |
| haloprogin | Cavia porcellus (domestic guinea pig) | IC50 | 2.6020 | 1 | 0 |
| haloprogin | Cavia porcellus (domestic guinea pig) | Ki | 1.3630 | 1 | 0 |
| hexachlorophene | Cavia porcellus (domestic guinea pig) | IC50 | 4.6042 | 1 | 0 |
| hexachlorophene | Cavia porcellus (domestic guinea pig) | Ki | 2.4117 | 1 | 0 |
| ketotifen | Cavia porcellus (domestic guinea pig) | IC50 | 0.1600 | 1 | 0 |
| ketotifen | Cavia porcellus (domestic guinea pig) | Ki | 0.0840 | 1 | 0 |
| 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one | Cavia porcellus (domestic guinea pig) | IC50 | 1.0020 | 1 | 0 |
| 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one | Cavia porcellus (domestic guinea pig) | Ki | 0.5250 | 1 | 0 |
| maprotiline | Cavia porcellus (domestic guinea pig) | IC50 | 0.0780 | 1 | 0 |
| maprotiline | Cavia porcellus (domestic guinea pig) | Ki | 0.0410 | 1 | 0 |
| methapyrilene | Cavia porcellus (domestic guinea pig) | IC50 | 0.7440 | 1 | 0 |
| methapyrilene | Cavia porcellus (domestic guinea pig) | Ki | 0.3900 | 1 | 0 |
| metoclopramide | Cavia porcellus (domestic guinea pig) | IC50 | 2.3830 | 1 | 0 |
| metoclopramide | Cavia porcellus (domestic guinea pig) | Ki | 1.2480 | 1 | 0 |
| mianserin | Cavia porcellus (domestic guinea pig) | IC50 | 0.0012 | 1 | 0 |
| mianserin | Cavia porcellus (domestic guinea pig) | Ki | 0.0006 | 1 | 0 |
| miconazole | Cavia porcellus (domestic guinea pig) | IC50 | 5.3140 | 1 | 0 |
| miconazole | Cavia porcellus (domestic guinea pig) | Ki | 2.7840 | 1 | 0 |
| mitoxantrone | Cavia porcellus (domestic guinea pig) | IC50 | 3.5619 | 1 | 0 |
| mitoxantrone | Cavia porcellus (domestic guinea pig) | Ki | 1.8657 | 1 | 0 |
| nifedipine | Cavia porcellus (domestic guinea pig) | IC50 | 18.2730 | 1 | 0 |
| nifedipine | Cavia porcellus (domestic guinea pig) | Ki | 9.5720 | 1 | 0 |
| nortriptyline | Cavia porcellus (domestic guinea pig) | IC50 | 0.0160 | 1 | 0 |
| nortriptyline | Cavia porcellus (domestic guinea pig) | Ki | 0.0082 | 1 | 0 |
| orphenadrine | Cavia porcellus (domestic guinea pig) | IC50 | 0.5340 | 1 | 0 |
| orphenadrine | Cavia porcellus (domestic guinea pig) | Ki | 0.2800 | 1 | 0 |
| oxymetazoline | Cavia porcellus (domestic guinea pig) | IC50 | 0.5780 | 1 | 0 |
| oxymetazoline | Cavia porcellus (domestic guinea pig) | Ki | 0.3030 | 1 | 0 |
| pentamidine | Cavia porcellus (domestic guinea pig) | IC50 | 3.2780 | 1 | 0 |
| pentamidine | Cavia porcellus (domestic guinea pig) | Ki | 1.7170 | 1 | 0 |
| prochlorperazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0780 | 1 | 0 |
| prochlorperazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0410 | 1 | 0 |
| promazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0990 | 1 | 0 |
| promazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0520 | 1 | 0 |
| promethazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0120 | 1 | 0 |
| promethazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0065 | 1 | 0 |
| propafenone | Cavia porcellus (domestic guinea pig) | IC50 | 0.3840 | 1 | 0 |
| propafenone | Cavia porcellus (domestic guinea pig) | Ki | 0.2010 | 1 | 0 |
| propofol | Cavia porcellus (domestic guinea pig) | IC50 | 11.5530 | 1 | 0 |
| propofol | Cavia porcellus (domestic guinea pig) | Ki | 6.0510 | 1 | 0 |
| propranolol | Cavia porcellus (domestic guinea pig) | IC50 | 2.2940 | 1 | 0 |
| propranolol | Cavia porcellus (domestic guinea pig) | Ki | 1.2020 | 1 | 0 |
| pyrilamine | Cavia porcellus (domestic guinea pig) | IC50 | 1.1300 | 1 | 0 |
| pyrilamine | Cavia porcellus (domestic guinea pig) | Ki | 0.5920 | 1 | 0 |
| quetiapine | Cavia porcellus (domestic guinea pig) | IC50 | 3.3008 | 1 | 0 |
| quetiapine | Cavia porcellus (domestic guinea pig) | Ki | 1.7290 | 1 | 0 |
| quipazine | Cavia porcellus (domestic guinea pig) | Ki | 10.0000 | 3 | 3 |
| raloxifene | Cavia porcellus (domestic guinea pig) | IC50 | 1.1780 | 1 | 0 |
| raloxifene | Cavia porcellus (domestic guinea pig) | Ki | 0.6170 | 1 | 0 |
| risperidone | Cavia porcellus (domestic guinea pig) | IC50 | 0.0150 | 1 | 0 |
| risperidone | Cavia porcellus (domestic guinea pig) | Ki | 0.0494 | 2 | 1 |
| sdz 205-557 | Cavia porcellus (domestic guinea pig) | IC50 | 0.2512 | 1 | 1 |
| sdz 205-557 | Cavia porcellus (domestic guinea pig) | Ki | 0.1259 | 1 | 1 |
| sulconazole | Cavia porcellus (domestic guinea pig) | IC50 | 2.7850 | 1 | 0 |
| sulconazole | Cavia porcellus (domestic guinea pig) | Ki | 1.4590 | 1 | 0 |
| terfenadine | Cavia porcellus (domestic guinea pig) | IC50 | 1.2310 | 1 | 0 |
| terfenadine | Cavia porcellus (domestic guinea pig) | Ki | 0.6450 | 1 | 0 |
| tetracaine | Cavia porcellus (domestic guinea pig) | IC50 | 3.2680 | 1 | 0 |
| tetracaine | Cavia porcellus (domestic guinea pig) | Ki | 1.7120 | 1 | 0 |
| thioridazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0440 | 1 | 0 |
| thioridazine | Cavia porcellus (domestic guinea pig) | Ki | 0.0230 | 1 | 0 |
| trazodone | Cavia porcellus (domestic guinea pig) | IC50 | 0.0910 | 1 | 0 |
| trazodone | Cavia porcellus (domestic guinea pig) | Ki | 0.0470 | 1 | 0 |
| trioxsalen | Cavia porcellus (domestic guinea pig) | IC50 | 2.3560 | 1 | 0 |
| trioxsalen | Cavia porcellus (domestic guinea pig) | Ki | 1.2340 | 1 | 0 |
| phentolamine | Cavia porcellus (domestic guinea pig) | IC50 | 0.3960 | 1 | 0 |
| phentolamine | Cavia porcellus (domestic guinea pig) | Ki | 0.2070 | 1 | 0 |
| 2-acetylaminofluorene | Cavia porcellus (domestic guinea pig) | IC50 | 2.1430 | 1 | 0 |
| 2-acetylaminofluorene | Cavia porcellus (domestic guinea pig) | Ki | 1.1220 | 1 | 0 |
| mepazine | Cavia porcellus (domestic guinea pig) | IC50 | 0.4950 | 1 | 0 |
| mepazine | Cavia porcellus (domestic guinea pig) | Ki | 0.2590 | 1 | 0 |
| cyclizine | Cavia porcellus (domestic guinea pig) | IC50 | 1.0210 | 1 | 0 |
| cyclizine | Cavia porcellus (domestic guinea pig) | Ki | 0.5350 | 1 | 0 |
| phenothiazine | Cavia porcellus (domestic guinea pig) | IC50 | 2.2360 | 1 | 0 |
| phenothiazine | Cavia porcellus (domestic guinea pig) | Ki | 1.1710 | 1 | 0 |
| ergotamine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0560 | 1 | 0 |
| ergotamine | Cavia porcellus (domestic guinea pig) | Ki | 0.0290 | 1 | 0 |
| methylergonovine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0130 | 1 | 0 |
| methylergonovine | Cavia porcellus (domestic guinea pig) | Ki | 0.0066 | 1 | 0 |
| benzethonium chloride | Cavia porcellus (domestic guinea pig) | IC50 | 1.0270 | 1 | 0 |
| benzethonium chloride | Cavia porcellus (domestic guinea pig) | Ki | 0.5380 | 1 | 0 |
| sterogenol | Cavia porcellus (domestic guinea pig) | IC50 | 1.2880 | 1 | 0 |
| sterogenol | Cavia porcellus (domestic guinea pig) | Ki | 0.6740 | 1 | 0 |
| methysergide | Cavia porcellus (domestic guinea pig) | IC50 | 0.0021 | 1 | 0 |
| methysergide | Cavia porcellus (domestic guinea pig) | Ki | 0.0011 | 1 | 0 |
| dihydroergotamine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0900 | 1 | 0 |
| dihydroergotamine | Cavia porcellus (domestic guinea pig) | Ki | 0.0470 | 1 | 0 |
| dimenhydrinate | Cavia porcellus (domestic guinea pig) | IC50 | 0.6340 | 1 | 0 |
| dimenhydrinate | Cavia porcellus (domestic guinea pig) | Ki | 0.3320 | 1 | 0 |
| clemastine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0990 | 1 | 0 |
| clemastine | Cavia porcellus (domestic guinea pig) | Ki | 0.0520 | 1 | 0 |
| metergoline | Cavia porcellus (domestic guinea pig) | IC50 | 0.0007 | 1 | 0 |
| metergoline | Cavia porcellus (domestic guinea pig) | Ki | 0.0003 | 1 | 0 |
| lisuride | Cavia porcellus (domestic guinea pig) | IC50 | 0.0200 | 1 | 0 |
| lisuride | Cavia porcellus (domestic guinea pig) | Ki | 0.0100 | 1 | 0 |
| bromocriptine | Cavia porcellus (domestic guinea pig) | IC50 | 0.5320 | 1 | 0 |
| bromocriptine | Cavia porcellus (domestic guinea pig) | Ki | 0.2780 | 1 | 0 |
| dexchlorpheniramine | Cavia porcellus (domestic guinea pig) | IC50 | 2.3220 | 1 | 0 |
| dexchlorpheniramine | Cavia porcellus (domestic guinea pig) | Ki | 1.2170 | 1 | 0 |
| butaclamol | Cavia porcellus (domestic guinea pig) | Ki | 0.0018 | 1 | 1 |
| pergolide | Cavia porcellus (domestic guinea pig) | IC50 | 0.3790 | 1 | 0 |
| pergolide | Cavia porcellus (domestic guinea pig) | Ki | 0.1990 | 1 | 0 |
| sertraline | Cavia porcellus (domestic guinea pig) | IC50 | 1.0830 | 1 | 0 |
| sertraline | Cavia porcellus (domestic guinea pig) | Ki | 0.5673 | 1 | 0 |
| ergocornine | Cavia porcellus (domestic guinea pig) | IC50 | 0.1040 | 1 | 0 |
| ergocornine | Cavia porcellus (domestic guinea pig) | Ki | 0.0550 | 1 | 0 |
| msh release-inhibiting hormone | Cavia porcellus (domestic guinea pig) | Ki | 0.0601 | 1 | 1 |
| u 74006f | Cavia porcellus (domestic guinea pig) | IC50 | 0.7180 | 1 | 0 |
| u 74006f | Cavia porcellus (domestic guinea pig) | Ki | 0.3760 | 1 | 0 |
| gr 113808 | Cavia porcellus (domestic guinea pig) | Ki | 5.0000 | 2 | 2 |
| mosapride | Cavia porcellus (domestic guinea pig) | IC50 | 0.3966 | 1 | 0 |
| mosapride | Cavia porcellus (domestic guinea pig) | Ki | 0.2077 | 1 | 0 |
| sb 204070a | Cavia porcellus (domestic guinea pig) | IC50 | 0.0001 | 1 | 1 |
| sb 204070a | Cavia porcellus (domestic guinea pig) | Ki | 0.1585 | 1 | 1 |
| desloratadine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0300 | 1 | 0 |
| desloratadine | Cavia porcellus (domestic guinea pig) | Ki | 0.0160 | 1 | 0 |
| sc 53116 | Cavia porcellus (domestic guinea pig) | Ki | 0.0052 | 1 | 1 |
| ciladopa | Cavia porcellus (domestic guinea pig) | IC50 | 2.2000 | 1 | 1 |
| alpha-ergocryptine | Cavia porcellus (domestic guinea pig) | IC50 | 0.1470 | 1 | 0 |
| alpha-ergocryptine | Cavia porcellus (domestic guinea pig) | Ki | 0.0770 | 1 | 0 |
| atropine | Cavia porcellus (domestic guinea pig) | IC50 | 1.0120 | 1 | 0 |
| atropine | Cavia porcellus (domestic guinea pig) | Ki | 0.5300 | 1 | 0 |
| piboserod | Cavia porcellus (domestic guinea pig) | Ki | 0.5000 | 2 | 2 |
| 3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride | Cavia porcellus (domestic guinea pig) | Ki | 0.0190 | 1 | 1 |
| rs 23597-190 | Cavia porcellus (domestic guinea pig) | Ki | 0.6778 | 3 | 3 |
| rs 67333 | Cavia porcellus (domestic guinea pig) | Ki | 0.0039 | 1 | 1 |
| maduramicin | Cavia porcellus (domestic guinea pig) | IC50 | 0.0340 | 1 | 0 |
| maduramicin | Cavia porcellus (domestic guinea pig) | Ki | 0.0180 | 1 | 0 |
| terconazole | Cavia porcellus (domestic guinea pig) | IC50 | 6.9610 | 1 | 0 |
| terconazole | Cavia porcellus (domestic guinea pig) | Ki | 3.6460 | 1 | 0 |
| ergonovine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0210 | 1 | 0 |
| ergonovine | Cavia porcellus (domestic guinea pig) | Ki | 0.0110 | 1 | 0 |
| dihydroergocristine monomesylate | Cavia porcellus (domestic guinea pig) | IC50 | 0.2390 | 1 | 0 |
| dihydroergocristine monomesylate | Cavia porcellus (domestic guinea pig) | Ki | 0.1250 | 1 | 0 |
| diethylstilbestrol | Cavia porcellus (domestic guinea pig) | IC50 | 50.8190 | 1 | 0 |
| diethylstilbestrol | Cavia porcellus (domestic guinea pig) | Ki | 26.6190 | 1 | 0 |
| tropisetron | Cavia porcellus (domestic guinea pig) | IC50 | 3.1623 | 1 | 1 |
| tropisetron | Cavia porcellus (domestic guinea pig) | Ki | 0.0028 | 1 | 1 |
| flunarizine | Cavia porcellus (domestic guinea pig) | IC50 | 0.6690 | 1 | 0 |
| flunarizine | Cavia porcellus (domestic guinea pig) | Ki | 0.3510 | 1 | 0 |
| benztropine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0610 | 1 | 0 |
| benztropine | Cavia porcellus (domestic guinea pig) | Ki | 0.0320 | 1 | 0 |
| enclomiphene | Cavia porcellus (domestic guinea pig) | IC50 | 1.2720 | 1 | 0 |
| enclomiphene | Cavia porcellus (domestic guinea pig) | Ki | 0.6660 | 1 | 0 |
| tamoxifen | Cavia porcellus (domestic guinea pig) | IC50 | 0.4600 | 1 | 0 |
| tamoxifen | Cavia porcellus (domestic guinea pig) | Ki | 0.2410 | 1 | 0 |
| dapiprazole | Cavia porcellus (domestic guinea pig) | IC50 | 0.6250 | 1 | 0 |
| dapiprazole | Cavia porcellus (domestic guinea pig) | Ki | 0.3270 | 1 | 0 |
| prucalopride | Cavia porcellus (domestic guinea pig) | Ki | 3.9811 | 1 | 1 |
| bw 723c86 | Cavia porcellus (domestic guinea pig) | IC50 | 0.2043 | 1 | 0 |
| bw 723c86 | Cavia porcellus (domestic guinea pig) | Ki | 0.1070 | 1 | 0 |
| genistein | Cavia porcellus (domestic guinea pig) | IC50 | 14.9100 | 1 | 0 |
| genistein | Cavia porcellus (domestic guinea pig) | Ki | 7.8060 | 1 | 0 |
| 4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide | Cavia porcellus (domestic guinea pig) | Ki | 0.0200 | 1 | 1 |
| l 745870 | Cavia porcellus (domestic guinea pig) | Ki | 2.3000 | 1 | 1 |
| ml 10302 | Cavia porcellus (domestic guinea pig) | Ki | 0.0060 | 2 | 2 |
| guanabenz | Cavia porcellus (domestic guinea pig) | IC50 | 0.2040 | 1 | 0 |
| guanabenz | Cavia porcellus (domestic guinea pig) | Ki | 0.1070 | 1 | 0 |
| 2-ethyl-5-methoxy-n,n-dimethyltryptamine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0440 | 1 | 1 |
| rwj 68354 | Cavia porcellus (domestic guinea pig) | IC50 | 1.2370 | 1 | 0 |
| rwj 68354 | Cavia porcellus (domestic guinea pig) | Ki | 0.6480 | 1 | 0 |
| 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole | Cavia porcellus (domestic guinea pig) | IC50 | 0.6200 | 1 | 1 |
| clozapine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0320 | 2 | 1 |
| clozapine | Cavia porcellus (domestic guinea pig) | Ki | 0.0095 | 2 | 1 |
| olanzapine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0970 | 2 | 1 |
| olanzapine | Cavia porcellus (domestic guinea pig) | Ki | 0.0110 | 1 | 0 |
| tegaserod | Cavia porcellus (domestic guinea pig) | Ki | 10.0000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cisapride | Cavia porcellus (domestic guinea pig) | EC50 | 0.1000 | 1 | 1 |
| clofibrate | Cavia porcellus (domestic guinea pig) | EC50 | 55.0000 | 1 | 1 |
| fenofibrate | Cavia porcellus (domestic guinea pig) | EC50 | 30.0000 | 1 | 1 |
| bezafibrate | Cavia porcellus (domestic guinea pig) | EC50 | 50.0000 | 1 | 1 |
| sb 204070a | Cavia porcellus (domestic guinea pig) | Kd | 0.0000 | 1 | 1 |
| mk 767 | Cavia porcellus (domestic guinea pig) | EC50 | 1.0000 | 1 | 1 |
| muraglitazar | Cavia porcellus (domestic guinea pig) | EC50 | 0.2400 | 1 | 1 |
| gw 409544 | Cavia porcellus (domestic guinea pig) | EC50 | 0.0020 | 1 | 1 |
| drf 2725 | Cavia porcellus (domestic guinea pig) | EC50 | 3.2000 | 1 | 1 |
| tzd 18 | Cavia porcellus (domestic guinea pig) | EC50 | 0.0300 | 1 | 1 |
| ly 465608 | Cavia porcellus (domestic guinea pig) | EC50 | 0.1500 | 1 | 1 |
| td-5108 | Cavia porcellus (domestic guinea pig) | EC50 | 0.0126 | 1 | 1 |
| tegaserod | Cavia porcellus (domestic guinea pig) | EC50 | 0.0094 | 2 | 2 |