doxazosin has been researched along with Sensitivity and Specificity in 13 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension." | 6.70 | Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002) |
| "Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension." | 2.70 | Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002) |
| "(-)Doxazosin was monitored under positive ionization condition by multiple reaction monitoring (MRM) with an ESI source." | 1.43 | [Quantification of (-)doxazosin at very low concentration in rat plasma samples by SPE-LC-MS/MS]. ( Du, Q; Kong, DZ; Ren, LM; Zhang, PP, 2016) |
| " The assay has been successfully applied to plasma sample ana-lysis for pharmacokinetic study." | 1.33 | Validation and pharmacokinetic application of a method for determination of doxazosin in human plasma by high-performance liquid chromatography. ( Nermhom, P; Saraphanchotiwitthaya, A; Sripalakit, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, Q | 1 |
| Kong, DZ | 2 |
| Zhang, PP | 1 |
| Ren, LM | 2 |
| Zhen, YQ | 1 |
| Li, Q | 1 |
| Zhao, J | 1 |
| Liu, K | 1 |
| Zhong, D | 1 |
| Chen, X | 1 |
| Casuccio, A | 1 |
| Cillino, G | 1 |
| Pavone, C | 1 |
| Spitale, E | 1 |
| Cillino, S | 1 |
| Mulatero, P | 1 |
| Rabbia, F | 1 |
| Milan, A | 1 |
| Paglieri, C | 1 |
| Morello, F | 1 |
| Chiandussi, L | 1 |
| Veglio, F | 1 |
| Walden, PD | 1 |
| Globina, Y | 1 |
| Nieder, A | 1 |
| Sripalakit, P | 2 |
| Nermhom, P | 2 |
| Saraphanchotiwitthaya, A | 2 |
| Nageswara Rao, R | 1 |
| Nagaraju, D | 1 |
| Narasa Raju, A | 1 |
| Kim, YJ | 1 |
| Lee, Y | 1 |
| Kang, MJ | 1 |
| Huh, JS | 1 |
| Yoon, M | 1 |
| Lee, J | 1 |
| Choi, YW | 1 |
| Ji, HY | 1 |
| Park, EJ | 1 |
| Lee, KC | 1 |
| Lee, HS | 1 |
| van Mastrigt, R | 1 |
| Krämer, BK | 1 |
| Ittner, KP | 1 |
| Marienhagen, J | 1 |
1 trial available for doxazosin and Sensitivity and Specificity
| Article | Year |
|---|---|
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.
Topics: Aldosterone; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Confounding Factors, | 2002 |
12 other studies available for doxazosin and Sensitivity and Specificity
| Article | Year |
|---|---|
[Quantification of (-)doxazosin at very low concentration in rat plasma samples by SPE-LC-MS/MS].
Topics: Administration, Intravenous; Animals; Chromatography, Liquid; Doxazosin; Plasma; Prazosin; Rats; Sen | 2016 |
[Determination of doxazosin enantiomers in rat plasma and investigation of their chiral inversion].
Topics: Animals; Blood Chemical Analysis; Doxazosin; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Re | 2013 |
Enantioselective determination of doxazosin in human plasma by liquid chromatography-tandem mass spectrometry using ovomucoid chiral stationary phase.
Topics: Adrenergic alpha-1 Receptor Antagonists; Chromatography, Liquid; Doxazosin; Drug Stability; Humans; | 2010 |
Pharmacologic pupil dilation as a predictive test for the risk for intraoperative floppy-iris syndrome.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Cohort Studies; Doxazosin; Drug Combinations; Humans; | 2011 |
Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase.
Topics: Anoikis; Caspase 3; Caspases; Doxazosin; Focal Adhesion Kinase 2; Humans; Immunoblotting; Male; Pros | 2004 |
Improvement of doxazosin determination in human plasma using high-performance liquid chromatography with fluorescence detection.
Topics: Blood Proteins; Chemical Precipitation; Chromatography, High Pressure Liquid; Doxazosin; Humans; Met | 2005 |
Validation and pharmacokinetic application of a method for determination of doxazosin in human plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Doxazosin; Drug Stability; Humans; Male; Reproducibility of Re | 2006 |
Enantiomeric resolution of doxazosin mesylate and its process-related substances on polysaccharide chiral stationary phases.
Topics: Adrenergic alpha-Antagonists; Chromatography, High Pressure Liquid; Doxazosin; Polysaccharides; Repr | 2006 |
High-performance liquid chromatographic determination of doxazosin in human plasma for bioequivalence study of controlled release doxazosin tablets.
Topics: Chromatography, High Pressure Liquid; Delayed-Action Preparations; Doxazosin; Drug Stability; Humans | 2006 |
Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.
Topics: Chromatography, Liquid; Cisapride; Doxazosin; Humans; Quality Control; Reference Standards; Sensitiv | 2008 |
Quantification of lower urinary tract function and dysfunction.
Topics: Doxazosin; Female; Humans; Male; Muscle Contraction; Pilot Projects; Postoperative Period; Prostate; | 1993 |
Diagnostic strategies in renovascular hypertension.
Topics: Captopril; Doxazosin; Humans; Hypertension, Renovascular; Radioisotope Renography; Renal Artery; Ren | 1996 |