Page last updated: 2024-08-07 17:31:50
Transient receptor potential cation channel subfamily V member 2
A transient receptor potential cation channel TRPV2 that is encoded in the genome of rat. [OMA:Q9WUD2, PRO:DNx]
Synonyms
TrpV2;
Osm-9-like TRP channel 2;
OTRPC2;
Stretch-activated channel 2B;
Vanilloid receptor-like protein 1;
VRL-1
Research
Bioassay Publications (13)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
Compounds (30)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| palmitic acid | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| clemizole | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 1 | 1 |
| haloperidol | Rattus norvegicus (Norway rat) | Ki | 0.0050 | 1 | 1 |
| palmidrol | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| arachidic acid | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| stearoylethanolamide | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| hexadecanamide | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| arachidonic acid | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| oleic acid | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| cannabidiol | Rattus norvegicus (Norway rat) | IC50 | 1.1000 | 1 | 1 |
| capsazepine | Rattus norvegicus (Norway rat) | IC50 | 162.9750 | 4 | 4 |
| erucic acid | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| anandamide | Rattus norvegicus (Norway rat) | IC50 | 4.7800 | 2 | 2 |
| oleylamide | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 2 | 2 |
| linoleoyl ethanolamide | Rattus norvegicus (Norway rat) | IC50 | 1.0250 | 2 | 2 |
| N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine | Rattus norvegicus (Norway rat) | IC50 | 5.8150 | 2 | 2 |
| n-oleoylethanolamine | Rattus norvegicus (Norway rat) | IC50 | 3.6000 | 2 | 2 |
| olvanil | Rattus norvegicus (Norway rat) | IC50 | 0.9300 | 2 | 2 |
| cannabigerol | Rattus norvegicus (Norway rat) | IC50 | 1.5000 | 1 | 1 |
| erucyl amide | Rattus norvegicus (Norway rat) | IC50 | 3.8850 | 2 | 2 |
| iodoresiniferatoxin | Rattus norvegicus (Norway rat) | IC50 | 4.0000 | 1 | 1 |
| linoleamide | Rattus norvegicus (Norway rat) | IC50 | 1.7000 | 2 | 2 |
| kjm 429 | Rattus norvegicus (Norway rat) | IC50 | 0.1100 | 2 | 2 |
| jyl 1421 | Rattus norvegicus (Norway rat) | IC50 | 0.0370 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cannabinol | Rattus norvegicus (Norway rat) | EC50 | 19.0000 | 1 | 1 |
| nonivamide | Rattus norvegicus (Norway rat) | EC50 | 0.5500 | 2 | 2 |
| dihydrocapsaicin | Rattus norvegicus (Norway rat) | EC50 | 0.1900 | 1 | 1 |
| cannabidiol | Rattus norvegicus (Norway rat) | EC50 | 1.2000 | 1 | 1 |
| capsaicin | Rattus norvegicus (Norway rat) | EC50 | 0.2460 | 4 | 5 |
| capsazepine | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| N-octylhomovanillamide | Rattus norvegicus (Norway rat) | EC50 | 0.3000 | 1 | 1 |
| olvanil | Rattus norvegicus (Norway rat) | EC50 | 0.1700 | 2 | 2 |
| cannabigerol | Rattus norvegicus (Norway rat) | EC50 | 1.7000 | 1 | 1 |
| ne 21610 | Rattus norvegicus (Norway rat) | EC50 | 0.2500 | 1 | 1 |