Compounds > carbazole
Page last updated: 2024-09-20

carbazole

Description

carbazole: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6854
CHEMBL ID243580
CHEBI ID27543
SCHEMBL ID7650
SCHEMBL ID6026794
MeSH IDM0123117

Synonyms (75)

Synonym
smr000112232
MLS001066363
CHEBI:27543 ,
chlorophenesin carbamate
wln: t b656 hmj
dibenzopyrrole
diphenyleneimine
nsc3498
9-azafluorene
usaf ek-600
diphenylenimide
nsc-3498
dibenzo[b,d]pyrrole
diphenylenimine
inchi=1/c12h9n/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13
NCGC00091233-01
hsdb 2164
einecs 201-696-0
dibenzo(b,d)pyrrole
ccris 121
skf 20091
nsc 3498
ai3-00096
86-74-8
9h-carbazole
carbazole
C08060
carbazole, >=95% (gc)
carbazole, analytical standard
NCGC00091233-02
MLS002415721
9h carbazole
DB07301
CHEMBL243580
BMSE000666
STK671343
AKOS000119129
A841825
NCGC00091233-03
cas-86-74-8
NCGC00256533-01
dtxcid40248
dtxsid4020248 ,
tox21_302847
tox21_201703
NCGC00259252-01
9ca ,
HMS2267P20
0p2197hhhn ,
ec 201-696-0
unii-0p2197hhhn
FT-0623455
PS-4072
carbazole [mi]
carbazole [hsdb]
carbazole [iarc]
SCHEMBL7650
9-h-carbazole
SCHEMBL6026794
Q-200795
STR04484
mfcd00004960
F0001-2148
carbazole, 96%
carbazole, vetranal(tm), analytical standard
AT24454
EN300-19085
carbazole, extra pure, 98%
Q424003
para-carbazole
carbazole 1000 microg/ml in methanol
51555-21-6
carbazole (high purity)
C3722
Z104472702

Research Excerpts

Overview

ExcerptReference
"The carbazole scaffold is an active structure showing anti-cancer biological activity, and the structural diversity has been expanded through the improvement and optimization of synthesizing methods."( Chen, YR; Li, KT; Ou, TM; Su, XX; Sun, JW; Wang, H; Wang, XN; Wu, JQ; Wu, XZ, 2022)
"Carbazole is an essential building block in various pharmaceuticals, agrochemicals, natural products, and materials. "( Cao, D; Li, CJ; Yu, J; Zeng, H, 2020)
"9H-carbazole is an aromatic molecule that is tricyclic in nature, with two benzene rings fused onto a 5-membered pyrrole ring. "( Gündisch, D; Sun, D; Tsutsumi, LS, 2016)
"Carbazole is a recalcitrant compound with a dioxin-like structure and possesses mutagenic and toxic activities. "( Deng, Z; Gai, Z; He, X; Liu, X; Tai, C; Tang, H; Wang, X; Wu, G; Xu, P, 2010)
"Carbazole is a promising pharmaceutical species. "( Chen, LX; Huang, GH; Niu, CG; Shen, GL; Yu, RQ; Zeng, GM, 2003)
"Carbazole is a nitrogen heterocyclic compound associated with fossil fuels and their products. "( Aislabie, J; Hunter, DW; Shotbolt-Brown, J, 1996)
"Carbazole (CA) is a heterocyclic nitrogen compound contained in the crude petroleum oil and recalcitrant to removal through the refinery processes. "( Kino, K; Kirimura, K; Kurane, R; Nakagawa, H; Nitta, T; Usami, S, 2002)

Effects

ExcerptReference
"Carbazole has a toxic influence on living organisms, and the knowledge of its persistence and bioconversion in ecosystems is still not complete."( Bernat, P; Felczak, A; Lisowska, K; Zawadzka, K, 2015)
"Carbazole derivatives have been reported as a kind of fluorescent probe with many excellent optical properties."( Fei, X; Gu, Y; Lin, D; Tang, Y; Wang, C; Zhang, B; Zhou, J, 2018)
"Lipocarbazole has recently been shown to be a powerful antioxidant in solution."( Banala, S; Berka, K; Calliste, CA; Fabre, G; Hänchen, A; Otyepka, M; Süssmuth, RD; Trouillas, P, 2015)
"Carbazole has a toxic influence on living organisms, and the knowledge of its persistence and bioconversion in ecosystems is still not complete."( Bernat, P; Felczak, A; Lisowska, K; Zawadzka, K, 2015)

Actions

ExcerptReference
"Carbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. "( Bagiński, M; Chylewska, A; Dąbrowska, AM; Maciejewska, N; Makowski, M; Olszewski, M; Ramotowska, S, 2020)
"Carbazole was found to inhibit rac activation as a mechanism for its inhibition of downstream inflammatory and angiogenic pathways."( Arbiser, JL; Battle, TE; Bowden, GT; Eissa, NT; Frank, DA; Govindarajan, B; Hossain, CF; Klein, E; Kolodziejski, PJ; Liu, A; Lynch, R; Nagle, DG; Perry, BN; Stern, DF; Ushio-Fukai, M, 2006)

Treatment

ExcerptReference
"Carbazole treatment also reduced activity of inducible nitric oxide synthase (iNOS), which is proinflammatory and elevated in psoriasis."( Arbiser, JL; Battle, TE; Bowden, GT; Eissa, NT; Frank, DA; Govindarajan, B; Hossain, CF; Klein, E; Kolodziejski, PJ; Liu, A; Lynch, R; Nagle, DG; Perry, BN; Stern, DF; Ushio-Fukai, M, 2006)

Drug Classes (1)

ClassDescription
carbazole
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

carbazole is involved in 1 pathway(s), involving a total of 6 unique proteins and 11 unique compounds

PathwayProteinsCompounds
carbazole degradation611

Protein Targets (24)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, HADH2 proteinHomo sapiens (human)Potency32.46480.025120.237639.8107AID886; AID893
Chain B, HADH2 proteinHomo sapiens (human)Potency32.46480.025120.237639.8107AID886; AID893
LuciferasePhotinus pyralis (common eastern firefly)Potency39.23210.007215.758889.3584AID1224835
ClpPBacillus subtilisPotency35.48131.995322.673039.8107AID651965
RAR-related orphan receptor gammaMus musculus (house mouse)Potency21.44030.006038.004119,952.5996AID1159521; AID1159523
AR proteinHomo sapiens (human)Potency24.16210.000221.22318,912.5098AID1259243; AID1259247; AID588515; AID743036
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.81070.011212.4002100.0000AID1030
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency35.03910.001022.650876.6163AID1224838; AID1224839; AID1224893
progesterone receptorHomo sapiens (human)Potency28.73620.000417.946075.1148AID1346795
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency30.91490.003041.611522,387.1992AID1159552; AID1159555
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency61.12710.001530.607315,848.9004AID1224841; AID1224848; AID1224849; AID1259403
pregnane X nuclear receptorHomo sapiens (human)Potency54.42510.005428.02631,258.9301AID1346982
estrogen nuclear receptor alphaHomo sapiens (human)Potency41.70330.000229.305416,493.5996AID1259244; AID743069
aryl hydrocarbon receptorHomo sapiens (human)Potency38.45310.000723.06741,258.9301AID743122
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency6.85900.001723.839378.1014AID743083
Histone H2A.xCricetulus griseus (Chinese hamster)Potency98.99900.039147.5451146.8240AID1224845
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency7.07953.548119.542744.6684AID743266
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency0.61130.000323.4451159.6830AID743065
histone deacetylase 9 isoform 3Homo sapiens (human)Potency53.54210.037617.082361.1927AID1259364
heat shock protein beta-1Homo sapiens (human)Potency61.64480.042027.378961.6448AID743210
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency68.58960.000627.21521,122.0200AID720636
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency53.54210.001557.789015,848.9004AID1259244
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency53.54210.001551.739315,848.9004AID1259244
Nuclear receptor ROR-gammaHomo sapiens (human)Potency26.60320.026622.448266.8242AID651802
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (13)

Processvia Protein(s)Taxonomy
negative regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
xenobiotic metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of glucose metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of steroid metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
intracellular receptor signaling pathwayNuclear receptor ROR-gammaHomo sapiens (human)
circadian regulation of gene expressionNuclear receptor ROR-gammaHomo sapiens (human)
cellular response to sterolNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of circadian rhythmNuclear receptor ROR-gammaHomo sapiens (human)
regulation of fat cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of DNA-templated transcriptionNuclear receptor ROR-gammaHomo sapiens (human)
adipose tissue developmentNuclear receptor ROR-gammaHomo sapiens (human)
T-helper 17 cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (10)

Processvia Protein(s)Taxonomy
RNA polymerase II cis-regulatory region sequence-specific DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
protein bindingNuclear receptor ROR-gammaHomo sapiens (human)
oxysterol bindingNuclear receptor ROR-gammaHomo sapiens (human)
zinc ion bindingNuclear receptor ROR-gammaHomo sapiens (human)
ligand-activated transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
sequence-specific double-stranded DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
nuclear receptor activityNuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (5)

Processvia Protein(s)Taxonomy
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
nucleoplasmNuclear receptor ROR-gammaHomo sapiens (human)
nuclear bodyNuclear receptor ROR-gammaHomo sapiens (human)
chromatinNuclear receptor ROR-gammaHomo sapiens (human)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (49)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1827138Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as inhibition of bacterial growth after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID293662Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis inhibition time at 9.26 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID293640Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis time at 15.4 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID727886Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 100 uM after 5 mins relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID318337Cytotoxicity against mock-infected MDBK cells by LDH method2008Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity.
AID1827215Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus COL assessed as oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID293637Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis time at 6.17 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID727892Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 30 uM after 72 hrs by WST8 assay relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID727901Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 1 uM after 72 hrs by spectrophotometric analysis relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID727899Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 10 uM after 72 hrs by spectrophotometric analysis relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID1827210Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus COL assessed as fold change in oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID727894Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 1 uM after 72 hrs by WST8 assay relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID727890Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 1 uM after 5 mins relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID1827143Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as fold change in oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID1827233Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as fold change in oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID727902Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 3 uM after 72 hrs by spectrophotometric analysis relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID293638Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis time at 9.26 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID727887Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 30 uM after 5 mins relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID727898Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID1827142Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID318336Antiviral activity against BVDV infected in MDBK cells assessed as reduction in viral induced cell destruction by MTT assay2008Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7
Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity.
AID293663Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis inhibition time at 12.3 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID491351Inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity at 20 uM after 30 mins by luciferase-derived luminescence assay2010Journal of medicinal chemistry, Jul-08, Volume: 53, Issue:13
Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds.
AID293641Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis time at 20.6 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID727888Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 10 uM after 5 mins relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID727893Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 3 uM after 72 hrs by WST8 assay relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID1827149Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus USA 100 assessed as fold change in oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID293665Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis inhibition time at 20.6 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID293639Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis time at 12.3 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID293661Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis inhibition time at 6.17 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID346025Binding affinity to beta cyclodextrin2009Bioorganic & medicinal chemistry, Jan-15, Volume: 17, Issue:2
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
AID727900Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells at 30 uM after 72 hrs by spectrophotometric analysis relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID1827238Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID1827235Potentiation of oxacillin induced antibacterial activity against methicillin-resistant Staphylococcus aureus USA100 assessed as oxacillin MIC at 50 uM after 18 hrs by CLSI protocol based broth microdilution assay2022ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3
Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA.
AID727889Inhibition of mushroom tyrosinase using L-DOPA as substrate after at 3 uM after 5 mins relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID293664Inhibition of AAPH-induced hemolysis in human erythrocytes assessed as hemolysis inhibition time at 15.4 uM2007Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
AID727891Cytotoxicity against mouse theophylline-induced B16-4A5 cells assessed as cell viability at 10 uM after 72 hrs by WST8 assay relative to control2013Bioorganic & medicinal chemistry, Mar-01, Volume: 21, Issue:5
Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
AID673777Cytotoxicity in UV-irradiated human U937 cells exposed to photosensitizer for 2 hrs before irradiation for 20 mins by WST-1 assay2012ACS medicinal chemistry letters, Apr-12, Volume: 3, Issue:4
Type 1 Phototherapeutic Agents. 2. Cancer Cell Viability and ESR Studies of Tricyclic Diarylamines.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1745845Primary qHTS for Inhibitors of ATXN expression
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (549)

TimeframeStudies, This Drug (%)All Drugs %
pre-199032 (5.83)18.7374
1990's17 (3.10)18.2507
2000's131 (23.86)29.6817
2010's318 (57.92)24.3611
2020's51 (9.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (0.18%)5.53%
Reviews19 (3.42%)6.00%
Case Studies1 (0.18%)4.05%
Observational0 (0.00%)0.25%
Other535 (96.22%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
phenothiazine[no description available]medium50phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger
5H-dibenzo[b,f]azepine[no description available]medium20dibenzoazepine;
mancude organic heterotricyclic parent		marine xenobiotic metabolite
diphenylamine[no description available]medium70aromatic amine;
bridged diphenyl fungicide;
secondary amino compound		antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger
phenoxazine[no description available]medium40phenoxazineferroptosis inhibitor;
radical scavenger
dibenzofuran[no description available]medium140dibenzofurans;
mancude organic heterotricyclic parent;
polycyclic heteroarene		xenobiotic
fluorene[no description available]medium170ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon
norharman[no description available]medium10beta-carbolines;
mancude organic heterotricyclic parent		fungal metabolite;
marine metabolite
alpha-carboline[no description available]medium10pyridoindole
gamma-carboline[no description available]medium10pyridoindole
4-hydroxybenzyl alcohol[no description available]medium10benzyl alcohols;
phenols		plant metabolite
4-hydroxybenzaldehyde[no description available]medium10hydroxybenzaldehydeEC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor;
mouse metabolite;
plant metabolite
4-hydroxybenzoic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
plant metabolite
ethylene glycol[no description available]medium10ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
acetaldehyde[no description available]medium20aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
acetone[no description available]medium20ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
benzaldehyde[no description available]medium10benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
benzene[no description available]medium10aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
benzoic acid[no description available]medium20benzoic acidsalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
benzyl alcohol[no description available]medium10benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
1-butanol[no description available]medium10alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
3-cresol[no description available]medium10cresolhuman xenobiotic metabolite
hydroquinone[no description available]medium10benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
methanol[no description available]medium20alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
acetanilide[no description available]medium10acetamides;
anilide		analgesic
n,n-dimethylaniline[no description available]medium20dimethylaniline;
tertiary amine
1-octanol[no description available]medium10octanol;
primary alcohol		antifungal agent;
bacterial metabolite;
fuel additive;
kairomone;
plant metabolite
4-nitrophenol[no description available]medium104-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
phenol[no description available]medium40phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
phenylacetic acid[no description available]medium10benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
1-propanol[no description available]medium10propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
toluene[no description available]medium20methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
acetohexamide[no description available]medium10acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
amobarbital[no description available]medium10barbiturates
barbital[no description available]medium10barbituratesdrug allergen
bendroflumethiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
benzocaine[no description available]medium10benzoate ester;
substituted aniline		allergen;
antipruritic drug;
sensitiser;
topical anaesthetic
butamben[no description available]medium10amino acid ester;
benzoate ester;
primary amino compound;
substituted aniline		local anaesthetic
4-cresol[no description available]medium20cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
diazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
dibenzothiophene[no description available]medium150dibenzothiophenes;
mancude organic heterotricyclic parent		keratolytic drug
fenbufen[no description available]medium104-oxo monocarboxylic acid;
biphenyls		non-steroidal anti-inflammatory drug
fludiazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound;
organofluorine compound		anxiolytic drug
flufenamic acid[no description available]medium10aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
flurbiprofen[no description available]medium10fluorobiphenyl;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
furosemide[no description available]medium10chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
hexobarbital[no description available]medium10barbiturates
hydrochlorothiazide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
2-propanol[no description available]medium10secondary alcohol;
secondary fatty alcohol		protic solvent
ketoprofen[no description available]medium10benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
meclofenamic acid[no description available]medium10aminobenzoic acid;
organochlorine compound;
secondary amino compound		analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
medazepam[no description available]medium10organic molecular entity
mefenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
vitamin k 3[no description available]medium101,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
fenamic acid[no description available]medium10aminobenzoic acid;
secondary amino compound		membrane transport modulator
nimetazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
GABA modulator;
sedative
nitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative
4-chlorophenol[no description available]medium10monochlorophenol
pentobarbital[no description available]medium10barbituratesGABAA receptor agonist
phenazine[no description available]medium10azaarene;
heteranthrene;
mancude organic heterotricyclic parent;
phenazines;
polycyclic heteroarene
phenobarbital[no description available]medium30barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
sulfadiazine[no description available]medium10pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
sulfadimethoxine[no description available]medium10aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
sulfamerazine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen
sulfamonomethoxine[no description available]medium10benzenes;
sulfonamide
sulfanilamide[no description available]medium10substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
sulfaphenazole[no description available]medium10primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor
sulfapyridine[no description available]medium10pyridines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
dermatologic drug;
drug allergen;
environmental contaminant;
xenobiotic
sulfisomidine[no description available]medium10pyrimidines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent
sulfisoxazole[no description available]medium10isoxazoles;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
drug allergen
tolnaftate[no description available]medium10monothiocarbamic esterantifungal drug
hydrocortisone acetate[no description available]medium10cortisol ester;
tertiary alpha-hydroxy ketone
cortisone acetate[no description available]medium10corticosteroid hormone
corticosterone[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
prednisolone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic
spironolactone[no description available]medium103-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
prednisolone acetate[no description available]medium10corticosteroid hormone
cyclobarbital[no description available]medium10barbiturates
allobarbital[no description available]medium10barbiturates
paramethasone[no description available]medium10fluorinated steroid
carbon tetrachloride[no description available]medium10chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
phenylethyl alcohol[no description available]medium10benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite
4-nitrobenzoic acid[no description available]medium10nitrobenzoic acid
aniline[no description available]medium20anilines;
primary arylamine
chloroform[no description available]medium10chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
fluocinolone acetonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
organic heteropentacyclic compound;
primary alpha-hydroxy ketone		anti-inflammatory drug;
antipruritic drug
4-hydroxypropiophenone[no description available]medium10acetophenones
n-pentanol[no description available]medium10pentanol;
short-chain primary fatty alcohol		human metabolite;
plant metabolite
acetonitrile[no description available]medium30aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
tert-butyl alcohol[no description available]medium10tertiary alcoholhuman xenobiotic metabolite
tert-amyl alcohol[no description available]medium10aliphatic alcohol;
tertiary alcohol		protic solvent
triamcinolone acetonide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
cyclic ketal;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
isobutyl alcohol[no description available]medium10alkyl alcohol;
primary alcohol		Saccharomyces cerevisiae metabolite
2-butanol[no description available]medium10secondary alcohol
p-tert-amylphenol[no description available]medium10alkylbenzene
dehydrocholic acid[no description available]medium1012-oxo steroid;
3-oxo-5beta-steroid;
7-oxo steroid;
oxo-5beta-cholanic acid		gastrointestinal drug
quinoline[no description available]medium80azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinolines
xanthenes[no description available]medium20xanthene
thianthrene[no description available]medium10mancude organic heterotricyclic parent;
organosulfur heterocyclic compound;
thianthrenes
benzidine[no description available]medium10biphenyls;
substituted aniline		carcinogenic agent
methyl benzoate[no description available]medium10benzoate ester;
methyl ester		insect attractant;
metabolite
ethyl benzoate[no description available]medium10benzoate ester;
ethyl ester		flavouring agent;
fragrance;
volatile oil component
butylparaben[no description available]medium10organic molecular entity
benzothiophene[no description available]medium401-benzothiophenes;
benzothiophene
benzothiazole[no description available]medium40benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic
cyclopentanol[no description available]medium10cyclopentanols
butylphen[no description available]medium10phenolsallergen
acetophenone[no description available]medium10acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
nitrobenzene[no description available]medium10nitroarene;
nitrobenzenes
4-isopropylphenol[no description available]medium10phenolsflavouring agent
4-hydroxyacetophenone[no description available]medium10monohydroxyacetophenonefungal metabolite;
mouse metabolite;
plant metabolite
4-chloronitrobenzene[no description available]medium10C-nitro compound
4-nitroaniline[no description available]medium10nitroanilinebacterial xenobiotic metabolite
ethylbenzene[no description available]medium10alkylbenzene
benzyl chloride[no description available]medium10benzyl chlorides
benzonitrile[no description available]medium10benzenes;
nitrile
methylaniline[no description available]medium10methylaniline;
phenylalkylamine;
secondary amine
anisole[no description available]medium10monomethoxybenzeneplant metabolite
phenetole[no description available]medium10aromatic ether
1,4-dibromobenzene[no description available]medium10dibromobenzene
4-bromophenol[no description available]medium10bromophenolhuman urinary metabolite;
human xenobiotic metabolite;
marine metabolite;
mouse metabolite;
persistent organic pollutant;
rat metabolite
4-xylene[no description available]medium10xylene
isobutylmethylcarbinol[no description available]medium10
3-chlorophenol[no description available]medium10monochlorophenol
bromobenzene[no description available]medium10bromoarene;
bromobenzenes;
volatile organic compound		hepatotoxic agent;
mouse metabolite;
non-polar solvent
cyclohexanol[no description available]medium10cyclohexanols;
secondary alcohol		solvent
methyl cellosolve[no description available]medium10glycol etherprotic solvent;
solvent
diethylamine[no description available]medium10secondary aliphatic amine
tetrahydrofuran[no description available]medium40cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
1,4-butanediol[no description available]medium10butanediol;
glycol		neurotoxin;
prodrug;
protic solvent
1-hexanol[no description available]medium10hexanol;
primary alcohol		alarm pheromone;
antibacterial agent;
fragrance;
plant metabolite
1,5-pentanediol[no description available]medium10primary alcohol
heptanol[no description available]medium10heptanol;
primary alcohol		flavouring agent;
fragrance;
gap junctional intercellular communication inhibitor;
plant metabolite
mephobarbital[no description available]medium10barbituratesanticonvulsant
ethyl-p-hydroxybenzoate[no description available]medium10ethyl ester;
paraben		antifungal agent;
antimicrobial food preservative;
phytoestrogen;
plant metabolite
2-methylbutanol[no description available]medium10alkyl alcohol;
primary alcohol		Saccharomyces cerevisiae metabolite
p-cresyl acetate[no description available]medium10benzoate ester;
phenols
3-hydroxyanisole[no description available]medium10monomethoxybenzene;
phenols
mequinol[no description available]medium10methoxybenzenes;
phenols		metabolite
phenanthridine[no description available]medium10azaarene;
mancude organic heterotricyclic parent;
phenanthridines;
polycyclic heteroarene
acridines[no description available]medium50acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
carbutamide[no description available]medium10benzenes;
sulfonamide
4-fluorophenol[no description available]medium10fluorophenol;
monofluorobenzenes
3-fluorophenol[no description available]medium10
betamethasone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent
fluorobenzenes[no description available]medium20monofluorobenzenesNMR chemical shift reference compound
3,3-dimethyl-2-butanol[no description available]medium10
chenodeoxycholic acid[no description available]medium10bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
phloroglucinol dimethyl ether[no description available]medium10methoxybenzenes;
phenols
1,3-propanediol[no description available]medium10propane-1,3-diolsmetabolite;
protic solvent
phenylacetylene[no description available]medium10benzenes
4-iodophenol[no description available]medium10iodophenol
3-bromophenol[no description available]medium10
3,5-dichlorophenol[no description available]medium10dichlorophenol
iodobenzene[no description available]medium10
3-isopropylphenol[no description available]medium10
3-ethylphenol[no description available]medium10phenols
4-Ethoxyphenol[no description available]medium10aromatic ether;
phenols
2-hexanol[no description available]medium10hexanol;
secondary alcohol		human metabolite;
plant metabolite;
semiochemical
hexamethylene glycol[no description available]medium10diol;
primary alcohol
4-propylphenol[no description available]medium10alkylbenzene
4-nitrophenyl acetate[no description available]medium10C-nitro compound;
phenyl acetates
4-n-Butylphenol[no description available]medium10phenols
sulfamethomidine[no description available]medium10organic molecular entity
2-octanol[no description available]medium10octanol;
secondary alcohol		plant metabolite;
volatile oil component
hydrocortisone-17-butyrate[no description available]medium10butyrate ester;
cortisol ester;
primary alpha-hydroxy ketone		dermatologic drug;
drug allergen
4-n-Pentylphenol[no description available]medium10phenols
4-ethylphenol[no description available]medium10phenolsfungal xenobiotic metabolite
isopentyl alcohol[no description available]medium10alkyl alcohol;
primary alcohol;
volatile organic compound		antifungal agent;
Saccharomyces cerevisiae metabolite;
xenobiotic metabolite
triamcinolone[no description available]medium1011beta-hydroxy steroid;
16alpha-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug
ursodeoxycholic acid[no description available]medium10bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
progabide[no description available]medium10diarylmethane
1-n-butylimidazole[no description available]medium10
cresatin[no description available]medium10benzoate ester;
phenols
3-propylphenol[no description available]medium10
cyclobutanol[no description available]medium10
1-benzylimidazole[no description available]medium10
triflumizol[no description available]medium10
1-adamantaneacetic acid[no description available]medium10
cholic acid[no description available]medium1012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
cortisone[no description available]medium1011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
griseofulvin[no description available]medium101-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite
3-coumaric acid[no description available]medium103-coumaric acid
trans-4-coumaric acid[no description available]medium104-coumaric acidfood component;
mouse metabolite;
plant metabolite
cinnarizine[no description available]medium10diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist
thiopental[no description available]medium10barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
dinoprostone[no description available]medium10prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
epoprostenol[no description available]medium10prostaglandins Imouse metabolite
2-hydroxycarbazole[no description available]medium20
methyl carbazole-3-carboxylate[no description available]medium10carbazoles
3-methoxy-9H-carbazole[no description available]medium10carbazoles
harmine[no description available]medium10harmala alkaloidanti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
metabolite
Koenimbine[no description available]medium20carbazoles
4-hydroxycarbazole[no description available]medium40
mahanimbine[no description available]medium20carbazoles
arbutin[no description available]medium10beta-D-glucoside;
monosaccharide derivative		Escherichia coli metabolite;
plant metabolite
acridone[no description available]medium10acridines;
cyclic ketone
acridan[no description available]medium10
dibenzylamine[no description available]medium10
10-methyl-9,10-dihydroacridine[no description available]medium10
carprofen[no description available]medium10carbazoles;
organochlorine compound		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
photosensitizing agent
methicillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
oxacillin[no description available]medium10penicillinantibacterial agent;
antibacterial drug
ampicillin[no description available]medium10beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
3,6-dichlorocarbazole[no description available]medium10
cefoxitin[no description available]medium10beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug
3,6-dimethoxy-9H-carbazole[no description available]medium10carbazoles
ceftazidime[no description available]medium10cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
proline[no description available]medium20amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
phenylalanine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
tryptophan[no description available]medium30erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
palladium[no description available]medium140metal allergen;
nickel group element atom;
platinum group metal atom
ellipticine[no description available]medium60indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite
benzo(a)pyrene[no description available]medium30ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
acetylcysteine[no description available]medium10acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
diphenyleneiodonium[no description available]medium10organic cation
hydrogen[no description available]medium50elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
perovskite[no description available]medium20
thiophenes[no description available]medium250mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
diphenyl[no description available]medium20aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative
piperazine[no description available]medium10azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
dehydroabietic acid[no description available]medium10abietane diterpenoid;
carbotricyclic compound;
monocarboxylic acid		allergen;
metabolite
9-methoxyellipticine[no description available]medium10
indole[no description available]medium120indole;
polycyclic heteroarene		Escherichia coli metabolite
1,3,4-oxadiazole[no description available]medium10
oxadiazoles[no description available]medium50
cyclohexene oxide[no description available]medium10
n-butyl vinyl ether[no description available]medium10
cobalt[no description available]medium30cobalt group element atom;
metal allergen		micronutrient
cadmium sulfide[no description available]medium20cadmium molecular entity
neutral red[no description available]medium20hydrochlorideacid-base indicator;
dye;
two-colour indicator
chromium dioxide[no description available]medium10
2,2'-biphenol[no description available]medium10hydroxybiphenyls
ammonium hydroxide[no description available]medium10azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
7h-dibenzo(c,g)carbazole[no description available]medium10carbazoles
thiobarbituric acid[no description available]medium10barbituratesallergen;
reagent
hypochlorous acid[no description available]medium20chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
stilbenes[no description available]medium20stilbene
mercury[no description available]medium30elemental mercury;
zinc group element atom		neurotoxin
uracil[no description available]medium20pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
cytosine[no description available]medium10aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyrazines[no description available]medium30diazine;
pyrazines		Daphnia magna metabolite
2,7-fluorenediamine[no description available]medium10
heptaphylline[no description available]medium20carbazolesmetabolite
glucosamine[no description available]medium20D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
memantine[no description available]medium10adamantanes;
primary aliphatic amine		antidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
amantadine[no description available]medium10adamantanes;
primary aliphatic amine		analgesic;
antiparkinson drug;
antiviral drug;
dopaminergic agent;
NMDA receptor antagonist;
non-narcotic analgesic
titanium[no description available]medium40titanium group element atom
phthalocyanine[no description available]medium10phthalocyanines;
tetrapyrrole fundamental parent
triazoles[no description available]medium201,2,3-triazole
methane[no description available]medium50alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
urea[no description available]medium30isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
calothrixin b[no description available]medium10
warfarin[no description available]medium20benzenes;
hydroxycoumarin;
methyl ketone
chalcone[no description available]medium20chalconeEC 3.2.1.1 (alpha-amylase) inhibitor
phenyl acetate[no description available]medium20benzenes;
phenyl acetates
cyanoacetic acid[no description available]medium10monocarboxylic acid
piperidines[no description available]medium10
silver[no description available]medium30copper group element atom;
elemental silver		Escherichia coli metabolite
piperidine[no description available]medium10azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine		base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent
thiourea[no description available]medium10one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
2-aminothiazole[no description available]medium101,3-thiazoles;
primary amino compound
cinnamamide[no description available]medium10cinnamamide
thiazoles[no description available]medium201,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
benzofurans[no description available]medium130
oxidopamine[no description available]medium10benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
benzo-1,2,3-thiadiazole[no description available]medium60
naphthalimides[no description available]medium20
oligonucleotides[no description available]medium20
anthracene[no description available]medium40acene;
anthracenes;
ortho-fused tricyclic hydrocarbon
phenanthrene[no description available]medium20ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon;
phenanthrenes		environmental contaminant;
mouse metabolite
phenanthrenes[no description available]medium20
oxazolidine[no description available]medium10oxazolidine
oxazoles[no description available]medium101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
alanine[no description available]medium10alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
gold[no description available]medium30copper group element atom;
elemental gold
rhodanine[no description available]medium20thiazolidinone
indole-3-carbinol[no description available]medium10indolyl alcoholantineoplastic agent;
plant metabolite
resveratrol[no description available]medium10resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
platinum[no description available]medium10elemental platinum;
nickel group element atom;
platinum group metal atom
cadmium[no description available]medium20cadmium molecular entity;
zinc group element atom
cytochrome c-t[no description available]medium10
bromide[no description available]medium20halide anion;
monoatomic bromine
cysteine[no description available]medium20cysteiniumfundamental metabolite
monoisopropanolamine[no description available]medium10amino alcohol;
secondary alcohol		Escherichia coli metabolite
quinone[no description available]medium301,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite
pyridine[no description available]medium70azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
carbocyanines[no description available]medium50cyanine dye;
organic iodide salt		fluorochrome
mahanine[no description available]medium30
2-(2'-pyridyl)benzimidazole[no description available]medium10
iridium[no description available]medium50cobalt group element atom;
platinum group metal atom
imidazole[no description available]medium20imidazole
ruthenium[no description available]medium20iron group element atom;
platinum group metal atom
ethidium[no description available]medium10phenanthridinesfluorochrome;
intercalator
acetylene[no description available]medium20alkyne;
gas molecular entity;
terminal acetylenic compound
2-phenylindole[no description available]medium10phenylindole
perylene[no description available]medium10ortho- and peri-fused polycyclic arene;
perylenes
2,2'-dipyridyl[no description available]medium10bipyridinechelator;
ferroptosis inhibitor
platinum tetrachloride[no description available]medium10platinum coordination entitycatalyst;
reagent
fullerene c60[no description available]medium30fullerenegeroprotector
ferrous sulfate[no description available]medium10iron molecular entity;
metal sulfate		reducing agent
fenton's reagent[no description available]medium10
picric acid[no description available]medium10C-nitro compoundantiseptic drug;
explosive;
fixative
pentamethylbenzene[no description available]medium10methylbenzene
benzyne[no description available]medium10aryne;
benzyne
indoline[no description available]medium10indoles
pyrroles[no description available]medium80pyrrole;
secondary amine
sulfur[no description available]medium40chalcogen;
nonmetal atom		macronutrient
phthalic anhydride[no description available]medium102-benzofurans;
cyclic dicarboxylic anhydride		allergen
symclosene[no description available]medium101,3,5-triazinanes;
organochlorine compound
xanthone[no description available]medium10xanthonesinsecticide
zirconium[no description available]medium20titanium group element atom
tacrine[no description available]medium10acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor
picolinamide[no description available]medium10pyridinecarboxamide
cocaine[no description available]medium30benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
naphthalene[no description available]medium30naphthalenes;
ortho-fused bicyclic arene		apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component
tin[no description available]medium10carbon group element atom;
elemental tin;
metal atom		micronutrient
benzimidazole[no description available]medium20benzimidazole;
polycyclic heteroarene
europium[no description available]medium30f-block element atom;
lanthanoid atom
ether[no description available]medium10ether;
volatile organic compound		inhalation anaesthetic;
non-polar solvent;
refrigerant
lead[no description available]medium10carbon group element atom;
elemental lead;
metal atom		neurotoxin
dimethyl maleate[no description available]medium10diester;
maleate ester;
methyl ester
carbazomycin b[no description available]medium10
carbazomycin a[no description available]medium10
indole-3-carbaldehyde[no description available]medium10heteroarenecarbaldehyde;
indole alkaloid;
indoles		bacterial metabolite;
human xenobiotic metabolite;
marine metabolite;
plant metabolite
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
2-phenylpyridine[no description available]medium10
carbostyril[no description available]medium10monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
indazoles[no description available]medium10indazole
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
nitrates[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
isoprene[no description available]medium20alkadiene;
hemiterpene;
volatile organic compound		plant metabolite
rhodium[no description available]medium20cobalt group element atom
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
o-methylmurrayamine a[no description available]medium10
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
7-hydroxycoumarin[no description available]medium10hydroxycoumarinfluorescent probe;
food component;
plant metabolite
murrayanine[no description available]medium20carbazolesmetabolite
coumarin[no description available]medium10coumarinsfluorescent dye;
human metabolite;
plant metabolite
xanthyletine[no description available]medium10coumarins
adicardin[no description available]medium10
pyrene[no description available]medium60ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
pyrimidine[no description available]medium10diazine;
pyrimidines		Daphnia magna metabolite
colchicine[no description available]medium20alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
iodine[no description available]medium20halide anion;
monoatomic iodine		human metabolite
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
temozolomide[no description available]medium10imidazotetrazine;
monocarboxylic acid amide;
triazene derivative		alkylating agent;
antineoplastic agent;
prodrug
dacarbazine[no description available]medium10dacarbazine
titanium dioxide[no description available]medium20titanium oxidesfood colouring
deferoxamine[no description available]medium10acyclic desferrioxaminebacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore
zinc hematoporphyrin[no description available]medium20
cyanides[no description available]medium30pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
acrylonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		antifungal agent;
carcinogenic agent;
fungal metabolite;
mutagen;
polar aprotic solvent
1,2,4-triazine[no description available]medium101,2,4-triazines;
triazine
biotin[no description available]medium10biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
hydroxyproline[no description available]medium104-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
alkenes[no description available]medium10
tjipanazole d[no description available]medium10
pyrrolidine dithiocarbamate[no description available]medium10dithiocarbamic acids;
pyrrolidines		anticonvulsant;
antineoplastic agent;
geroprotector;
neuroprotective agent;
NF-kappaB inhibitor;
radical scavenger
amyloid beta-peptides[no description available]medium10
singlet oxygen[no description available]medium10chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
murrayafoline a[no description available]medium10
9-fluorenone[no description available]medium10fluoren-9-onesfungal xenobiotic metabolite
fluoranthene[no description available]medium10ortho- and peri-fused polycyclic arene
dibenzo(1,4)dioxin[no description available]medium30dibenzodioxine;
heteranthrene;
mancude organic heterotricyclic parent;
oxacycle;
polycyclic heteroarene
anthranilic acid[no description available]medium70aminobenzoic acidhuman metabolite;
mouse metabolite
trifluoroacetic acid[no description available]medium10fluoroalkanoic acidhuman xenobiotic metabolite;
NMR chemical shift reference compound;
reagent
succinic acid[no description available]medium20alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
catechol[no description available]medium20catecholsallelochemical;
genotoxin;
plant metabolite
diclofenac[no description available]medium10amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
1,1-diphenyl-2-picrylhydrazyl[no description available]medium10
benzofuran[no description available]medium101-benzofurans;
benzofuran
fluorides[no description available]medium20halide anion;
monoatomic fluorine
fosbretabulin[no description available]medium10
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
alpha-terthienyl[no description available]medium10terthiophene
casein kinase ii[no description available]medium10
abacavir[no description available]medium102,6-diaminopurinesantiviral drug;
drug allergen;
HIV-1 reverse transcriptase inhibitor
tert-butyl acrylate[no description available]medium10
styrene[no description available]medium30styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
triethylenediamine[no description available]medium10bridged compound;
diamine;
saturated organic heterobicyclic parent;
tertiary amino compound		antioxidant;
catalyst;
reagent
n-vinyl-2-pyrrolidinone[no description available]medium10pyrrolidin-2-ones
sodium sulfide[no description available]medium10
tartaric acid[no description available]medium10tartaric acidEscherichia coli metabolite
aluminum[no description available]medium20boron group element atom;
elemental aluminium;
metal atom
quinoxalines[no description available]medium20mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
phosphine[no description available]medium10mononuclear parent hydride;
phosphanes;
phosphine		carcinogenic agent;
fumigant insecticide
2-methylpentane[no description available]medium20alkane
methylene chloride[no description available]medium10chloromethanes;
volatile organic compound		carcinogenic agent;
polar aprotic solvent;
refrigerant
azides[no description available]medium20pseudohalide anionmitochondrial respiratory-chain inhibitor
thiazole orange[no description available]medium10cyanine dyefluorochrome
olivacine[no description available]medium10
murrayaquinone a[no description available]medium10
cesium carbonate[no description available]medium10
cesium[no description available]medium10alkali metal atom
molybdenum trioxide[no description available]medium10molybdenum oxide
molybdenum[no description available]medium10chromium group element atommicronutrient
carbonates[no description available]medium10carbon oxoanion
hydroxyl radical[no description available]medium10oxygen hydride;
oxygen radical;
reactive oxygen species
ozone[no description available]medium10elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen		antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer
heme[no description available]medium10
caffeine[no description available]medium10purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
2-naphthol[no description available]medium10naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
cyanine dye 3[no description available]medium10
yo-pro 1[no description available]medium10cyanine dye;
organic iodide salt;
quaternary ammonium salt		fluorochrome
benzoxazoles[no description available]medium101,3-benzoxazoles;
mancude organic heterobicyclic parent
3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene[no description available]medium10
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
rebeccamycin[no description available]medium30indolocarbazole;
N-glycosyl compound;
organic heterohexacyclic compound;
organochlorine compound
carbogen[no description available]medium10
xylose[no description available]medium10D-xylose
glucuronic acid[no description available]medium70D-glucuronic acidalgal metabolite
sodium benzoate[no description available]medium10organic sodium saltalgal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite
histamine[no description available]medium20aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
phenacetin[no description available]medium10acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
benzophenone[no description available]medium10benzophenonesphotosensitizing agent;
plant metabolite
thenoyltrifluoroacetone[no description available]medium10
1,3-dicyanobenzene[no description available]medium10nitrile
3-amino-9-ethylcarbazole[no description available]medium10carbazoles
prazosin[no description available]medium10aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
rhodamine 6g[no description available]medium10
clotrimazole[no description available]medium10conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
cp 65,526[no description available]medium10
carvedilol[no description available]medium10carbazoles;
secondary alcohol;
secondary amino compound		alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent
n-hexadecane[no description available]medium20long-chain alkanenon-polar solvent;
plant metabolite;
volatile oil component
acetyl coenzyme a[no description available]medium10acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
pyruvic acid[no description available]medium102-oxo monocarboxylic acidcofactor;
fundamental metabolite
alanylglycine[no description available]medium10
deoxycholic acid[no description available]medium10bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
betadex[no description available]medium20cyclodextrin
calixarenes[no description available]medium10
n-glycylalanine[no description available]medium10dipeptidemetabolite
polygalacturonic acid[no description available]medium20D-galacturonic acid
sulfuric acid[no description available]medium10sulfur oxoacidcatalyst
hexenuronic acid[no description available]medium10
iduronate[no description available]medium10idopyranuronic acid;
L-iduronic acid
chlortetracycline[no description available]medium10
argon[no description available]medium10monoatomic argon;
noble gas atom;
p-block element atom		food packaging gas;
neuroprotective agent
methylene blue[no description available]medium30organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
methotrexate[no description available]medium10dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
benzil[no description available]medium10alpha-diketone;
aromatic ketone
phenylglyoxal[no description available]medium10phenylacetaldehydes
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
n-methylcarbazole[no description available]medium20
glutamic acid[no description available]medium10glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
mtt formazan[no description available]medium10
formazans[no description available]medium10
allopurinol[no description available]medium10nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
n-formylmethionine leucyl-phenylalanine[no description available]medium10tripeptide
pectins[no description available]medium20D-galactopyranuronic acid
sodium salicylate[no description available]medium10organic molecular entity
acid phosphatase[no description available]medium10
thioacetamide[no description available]medium10thiocarboxamidehepatotoxic agent
methyldimethylaminoazobenzene[no description available]medium10
n-ethyl-n-hydroxyethylnitrosamine[no description available]medium10nitrosamine;
primary alcohol		carcinogenic agent
2-acetylaminofluorene[no description available]medium102-acetamidofluorenesantimitotic;
carcinogenic agent;
epitope;
mutagen
hexachlorocyclohexane[no description available]medium10chlorocyclohexane
diethylnitrosamine[no description available]medium10nitrosaminecarcinogenic agent;
hepatotoxic agent;
mutagen
boric acid[no description available]medium20boric acidsastringent
cetylpyridinium[no description available]medium10pyridinium ion
1,9-dimethylmethylene blue[no description available]medium20
nitrogen dioxide[no description available]medium10nitrogen oxide
sulfur dioxide[no description available]medium10sulfur oxideEscherichia coli metabolite;
food bleaching agent;
refrigerant
diisopropanolnitrosamine[no description available]medium10diol;
nitrosamine;
secondary alcohol		carcinogenic agent
n-nitroso(di-n-propyl)amine[no description available]medium10nitroso compound
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
dibutyl ether[no description available]medium20
1-chlorohexane[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Abnormalities, Autosome0low20
Abnormalities, Chromosomal0low20
Abnormalities, Chromosome0low20
Abnormalities, Congenital0low10
Acute Confusional Senile Dementia0low60
Acute Myelogenous Leukemia0low10
Acute Myeloid Leukemia0low10
Acute Myeloid Leukemia with Maturation0low10
Acute Myeloid Leukemia without Maturation0low10
Acute Promyelocytic Leukemia0low10
Adenocarcinoma of Lung0low10
Adenocarcinoma, Mucinous0low10
Adenoma0low10
Adenoma, Basal Cell0low10
Adenoma, Follicular0low10
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Trabecular0low10
African Sleeping Sickness0low10
African Trypanosomiasis0low10
Age-Related Memory Disorders0low10
Alloxan Diabetes0low30
alpha-L-Iduronidase Deficiency0low10
Alzheimer Dementia0low60
Alzheimer Disease0low60
Alzheimer Disease, Early Onset0low60
Alzheimer Disease, Late Onset0low60
Alzheimer Sclerosis0low60
Alzheimer Syndrome0low60
Alzheimer Type Senile Dementia0low60
Alzheimer-Type Dementia (ATD)0low60
Alzheimer's Disease0low60
Alzheimer's Disease, Focal Onset0low60
Alzheimer's Diseases0low60
AML M30low10
Amyloid Deposits0low10
Amyloid Plaques0low10
Amyloidosis0low10
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
Angiohemophilia0low10
ANLL0low10
Anoxemia0low10
Anoxia0low10
Astrocytoma, Grade IV0low10
Autosome Abnormalities0low20
Bacterial Disease0low10
Bacterial Infection0low10
Bacterial Infections0low10
Bedwetting0low10
Benign Neoplasms0low110
Benign Neoplasms, Brain0low10
Birth Defects0low10
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Blood Poisoning0low10
Bloodstream Infection0low10
Body Weight0low10
Brain Cancer0low10
Brain Metastases0low10
Brain Neoplasm, Primary0low10
Brain Neoplasms0low10
Brain Neoplasms, Benign0low10
Brain Neoplasms, Malignant0low10
Brain Neoplasms, Malignant, Primary0low10
Brain Neoplasms, Primary Malignant0low10
Brain Tumor, Primary0low10
Brain Tumor, Recurrent0low10
Brain Tumors0low10
Breast Cancer0low20
Breast Carcinoma0low20
Breast Neoplasms0low20
Breast Tumors0low20
Bronchial Neoplasms0low10
Cancer0low110
Cancer of Bladder0low10
Cancer of Brain0low10
Cancer of Breast0low20
Cancer of Kidney0low10
Cancer of Liver0low60
Cancer of Lung0low20
Cancer of Pancreas0low10
Cancer of Prostate0low10
Cancer of Stomach0low10
Cancer of the Bladder0low10
Cancer of the Brain0low10
Cancer of the Breast0low20
Cancer of the Kidney0low10
Cancer of the Liver0low60
Cancer of the Lung0low20
Cancer of the Pancreas0low10
Cancer of the Prostate0low10
Cancer of the Stomach0low10
Cancer of the Thyroid0low20
Cancer of Thyroid0low20
Cancer, Hepatocellular0low60
Carcinogenesis0low10
Carcinoma0low20
Carcinoma, Anaplastic0low20
Carcinoma, Colloid0low10
Carcinoma, Hepatocellular0low10
Carcinoma, Mucinous0low10
Carcinoma, Non-Small Cell Lung0low10
Carcinoma, Non-Small-Cell Lung0low10
Carcinoma, Spindle-Cell0low20
Carcinoma, Undifferentiated0low20
Carcinomatosis0low20
Cardiac Failure0medium11
Central Nervous System Neoplasm0low10
Central Nervous System Neoplasms0low10
Central Nervous System Neoplasms, Primary0low10
Central Nervous System Tumor0low10
Central Nervous System Tumors0low10
Chromosomal Aberrations0low20
Chromosome Aberrations0low20
Chromosome Abnormalities0low20
CNS Neoplasm0low10
CNS Neoplasms0low10
Cocarcinogenesis0low10
Cognition Disorders0low10
Colitis0low10
Condition, Preneoplastic0low10
Conditions, Preneoplastic0low10
Congenital Abnormalities0low10
Congenital Defects0low10
Congestive Heart Failure0medium11
Cystic Echinococcosis0low10
Cysts, Hydatid0low10
Cytogenetic Aberrations0low20
Cytogenetic Abnormalities0low20
Defects, Congenital0low10
Deficiency, Oxygen0low10
Deformities0low10
Degenerative Diseases, Central Nervous System0low10
Degenerative Diseases, Nervous System0low10
Degenerative Diseases, Neurologic0low10
Degenerative Diseases, Spinal Cord0low10
Degenerative Neurologic Diseases0low10
Degenerative Neurologic Disorders0low10
Dementia, Alzheimer Type0low60
Dementia, Presenile0low60
Dementia, Primary Senile Degenerative0low60
Dementia, Senile0low60
Dermatitis, Contact, Phototoxic0low10
Dermatitis, Phototoxic0low10
Diabetes Mellitus, Adult-Onset0low20
Diabetes Mellitus, Experimental0low30
Diabetes Mellitus, Ketosis-Resistant0low20
Diabetes Mellitus, Maturity-Onset0low20
Diabetes Mellitus, Non Insulin Dependent0low20
Diabetes Mellitus, Non-Insulin-Dependent0low20
Diabetes Mellitus, Noninsulin Dependent0low20
Diabetes Mellitus, Noninsulin-Dependent0low20
Diabetes Mellitus, Slow-Onset0low20
Diabetes Mellitus, Stable0low20
Diabetes Mellitus, Type 20low20
Diabetes Mellitus, Type II0low20
Disease Models, Animal0low20
Early Onset Alzheimer Disease0low60
Eccentro-Osteochondrodysplasia0low10
Eccentroosteochondrodysplasia0low10
Echinococcosis0low10
Echinococcus Granulosus Infection0low10
Echinococcus Infection0low10
Electrolytes0low20
Epithelial Neoplasms, Malignant0low20
Epithelial Tumors, Malignant0low20
Epithelioma0low20
Equine Diseases0low10
Experimental Diabetes Mellitus0low30
Experimental Hepatoma0low20
Experimental Hepatomas0low20
Experimental Liver Neoplasms0low20
Experimental Neoplasms0low40
Extravascular Hemolysis0low10
Familial Alzheimer Disease (FAD)0low60
Fetal Anomalies0low10
Fetal Malformations0low10
Focal Onset Alzheimer's Disease0low60
Fungal Diseases0low10
Fungal Infections0low10
Fungus Diseases0low10
Fungus Infections0low10
Galactosamine-6-Sulfatase Deficiency0low10
GALNS Deficiency0low10
Gargoylism0low10
Gargoylism, Hurler Syndrome0low10
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Genome Instability0low10
Genome Stability0low10
Genomic Instability0low10
Genomic Stability0low10
Giant Cell Glioblastoma0low10
Glioblastoma0low10
Glioblastoma Multiforme0low10
Group A Strep Infection0low10
Group A Streptococcal Infection0low10
Group A Streptococcal Infections0low10
Group B Strep Infection0low10
Group B Streptococcal Infection0low10
Group B Streptococcal Infections0low10
Haemolysis0low10
Heart Decompensation0medium11
Heart Failure0medium11
Heart Failure, Congestive0medium11
Heart Failure, Left-Sided0medium11
Heart Failure, Right-Sided0medium11
Hemolysis0low10
Hemophilia, Vascular0low10
Hepatic Cancer0low60
Hepatic Neoplasms0low60
Hepatocellular Cancer0low60
Hepatocellular Carcinoma0low10
Hepatoma0low10
Hepatoma, Experimental0low20
Hepatoma, Morris0low20
Hepatoma, Novikoff0low20
Hepatomas, Experimental0low20
Horse Diseases0low10
Human Mammary Carcinoma0low20
Hurler Disease0low10
Hurler Syndrome0low10
Hurler-Scheie Syndrome0low10
Hurler's Disease0low10
Hurler's Syndrome0low10
Hydatid Cyst0low10
Hydatid Disease0low10
Hydatidosis0low10
Hyperlipemia0low10
Hyperlipidemia0low10
Hyperlipidemias0low10
Hypoxemia0low10
Hypoxia0low10
Infection, Bacterial0low10
Infections, Bacterial0low10
Infections, Plasmodium0low10
Infections, Streptococcal0low10
Inflammation0low10
Innate Inflammatory Response0low10
Intracranial Neoplasms0low10
Intravascular Hemolysis0low10
Invasiveness, Neoplasm0low10
Kahler Disease0low10
Kidney Cancer0low10
Kidney Neoplasms0low10
Koch's Disease0low10
Kochs Disease0low10
Late Onset Alzheimer Disease0low60
Left-Sided Heart Failure0medium11
Leucocythaemia0low10
Leucocythemia0low10
Leukemia0low10
Leukemia, Acute Myelogenous0low10
Leukemia, Acute Myeloid0low10
Leukemia, Acute Promyelocytic0low10
Leukemia, Myeloblastic, Acute0low10
Leukemia, Myelocytic, Acute0low10
Leukemia, Myelogenous, Acute0low10
Leukemia, Myeloid, Acute0low10
Leukemia, Myeloid, Acute, M10low10
Leukemia, Myeloid, Acute, M20low10
Leukemia, Myeloid, Acute, M30low10
Leukemia, Nonlymphoblastic, Acute0low10
Leukemia, Nonlymphocytic, Acute0low10
Leukemia, Progranulocytic0low10
Leukemia, Promyelocytic, Acute0low10
Lipemia0low10
Lipidemia0low10
Lipochondrodystrophy0low10
Liver Cancer0low60
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Neoplasms0low60
Liver Neoplasms, Experimental0low20
Lung Adenocarcinoma0low10
Lung Cancer0low20
Lung Neoplasms0low20
M3 ANLL0low10
Malaria0low10
Malignancy0low110
Malignant Epithelial Neoplasms0low20
Malignant Melanoma0low10
Malignant Neoplasm of Breast0low20
Malignant Neoplasms0low110
Malignant Neoplasms, Brain0low10
Malignant Primary Brain Neoplasms0low10
Malignant Primary Brain Tumors0low10
Malignant Tumor of Breast0low20
Malignant Tumor of Urinary Bladder0low10
Mammary Cancer0low20
Mammary Carcinoma, Human0low20
Mammary Neoplasm, Human0low20
Mammary Neoplasms, Human0low20
Marsh Fever0low10
Maturity-Onset Diabetes0low20
Maturity-Onset Diabetes Mellitus0low20
Melanoma0low10
Memory Deficits0low10
Memory Disorder, Semantic0low10
Memory Disorder, Spatial0low10
Memory Disorders0low10
Memory Disorders, Age-Related0low10
Memory Loss0low10
MODY0low20
Morquio A Disease0low10
Morquio B Syndrome0low10
Morquio Disease0low10
Morquio Syndrome0low10
Morquio Syndrome A0low10
Morquio Syndrome B0low10
Morquio Syndrome, Type B0low10
Morquio-B Disease0low10
Morquio's Disease0low10
Morquio's Disease Type B0low10
Morquio's Syndrome0low10
MPS IV A0low10
MPS IV B0low10
MPS IVA0low10
MPS IVB0low10
Mucopolysaccharidoses0low10
Mucopolysaccharidosis0low10
Mucopolysaccharidosis 10low10
Mucopolysaccharidosis 40low10
Mucopolysaccharidosis 4B0low10
Mucopolysaccharidosis 50low10
Mucopolysaccharidosis I0low10
Mucopolysaccharidosis I-S0low10
Mucopolysaccharidosis IV0low10
Mucopolysaccharidosis Type I0low10
Mucopolysaccharidosis Type Ih0low10
Mucopolysaccharidosis Type Ih S0low10
Mucopolysaccharidosis Type Is0low10
Mucopolysaccharidosis Type IV0low10
Mucopolysaccharidosis Type IV A0low10
Mucopolysaccharidosis Type IV B0low10
Mucopolysaccharidosis Type IVA0low10
Mucopolysaccharidosis Type IVB0low10
Mucopolysaccharidosis V0low10
Multiple Myeloma0low10
Mycobacterium tuberculosis Infection0low10
Mycoses0low10
Myeloblastic Leukemia, Acute0low10
Myelocytic Leukemia, Acute0low10
Myelogenous Leukemia, Acute0low10
Myeloid Leukemia, Acute0low10
Myeloid Leukemia, Acute, M10low10
Myeloid Leukemia, Acute, M20low10
Myeloid Leukemia, Acute, M30low10
Myeloma-Multiple0low10
Myeloma, Multiple0low10
Myeloma, Plasma-Cell0low10
Myelomatosis0low10
Myocardial Failure0medium11
Nagana0low10
Nasopharyngeal Carcinoma0low10
Neoplasia0low110
Neoplasm0low110
Neoplasm Invasion0low10
Neoplasm Invasiveness0low10
Neoplasms0low110
Neoplasms, Benign0low110
Neoplasms, Bladder0low10
Neoplasms, Brain0low10
Neoplasms, Brain, Benign0low10
Neoplasms, Brain, Malignant0low10
Neoplasms, Brain, Primary0low10
Neoplasms, Breast0low20
Neoplasms, Bronchial0low10
Neoplasms, Central Nervous System0low10
Neoplasms, Experimental0low40
Neoplasms, Experimental Liver0low20
Neoplasms, Gastric0low10
Neoplasms, Hepatic0low60
Neoplasms, Intracranial0low10
Neoplasms, Kidney0low10
Neoplasms, Liver0low60
Neoplasms, Lung0low20
Neoplasms, Malignant Epithelial0low20
Neoplasms, Pancreatic0low10
Neoplasms, Prostate0low10
Neoplasms, Prostatic0low10
Neoplasms, Pulmonary0low20
Neoplasms, Stomach0low10
Neoplasms, Thyroid0low20
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Nerve Pain0low10
Nervous System Degenerative Diseases0low10
Neuralgia0low10
Neuralgia, Atypical0low10
Neuralgia, Iliohypogastric Nerve0low10
Neuralgia, Ilioinguinal0low10
Neuralgia, Perineal0low10
Neuralgia, Stump0low10
Neuralgia, Supraorbital0low10
Neuralgia, Vidian0low10
Neuritic Plaques0low10
Neuroblastoma0low10
Neurodegenerative Diseases0low10
Neurodegenerative Disorders0low10
Neurodynia0low10
Neurologic Degenerative Conditions0low10
Neurologic Degenerative Diseases0low10
Neurologic Diseases, Degenerative0low10
Neuropathic Pain0low10
NIDDM0low20
Nighttime Urinary Incontinence0low10
Nocturnal Enuresis0low10
Non-Small Cell Lung Cancer0low10
Non-Small Cell Lung Carcinoma0low10
Non-Small-Cell Lung Carcinoma0low10
Noninsulin-Dependent Diabetes Mellitus0low20
Nonlymphoblastic Leukemia, Acute0low10
Nonlymphocytic Leukemia, Acute0low10
Nonsmall Cell Lung Cancer0low10
Obesity0low10
Oncogenesis0low10
Overinclusion0low10
Oxygen Deficiency0low10
Palmoplantaris Pustulosis0low20
Paludism0low10
Pancreas Cancer0low10
Pancreas Neoplasms0low10
Pancreatic Cancer0low10
Pancreatic Neoplasms0low10
Paroxysmal Nerve Pain0low10
Pathologic Angiogenesis0low10
Pathologic Neovascularization0low10
Pfaundler-Hurler Syndrome0low10
Phototoxic Contact Dermatitis0low10
Phototoxic Dermatitis0low10
Phototoxicity0low10
Plaque, Amyloid0low10
Plaques, Amyloid0low10
Plasma Cell Myeloma0low10
Plasmodium Infections0low10
Poisoning, Blood0low10
Precancerous Conditions0low10
Preneoplastic Condition0low10
Preneoplastic Conditions0low10
Presenile Alzheimer Dementia0low60
Primary Brain Neoplasms0low10
Primary Central Nervous System Neoplasm0low10
Primary Central Nervous System Neoplasms0low10
Primary Malignant Brain Neoplasms0low10
Primary Malignant Brain Tumors0low10
Primary Senile Degenerative Dementia0low60
Progranulocytic Leukemia0low10
Promyelocytic Leukemia, Acute0low10
Prostate Cancer0low10
Prostate Neoplasms0low10
Prostatic Cancer0low10
Prostatic Neoplasms0low10
Psoriasis0low20
Pulmonary Cancer0low20
Pulmonary Neoplasms0low20
Pustular Psoriasis of Palms and Soles0low20
Pustulosis of Palms and Soles0low20
Pustulosis Palmaris et Plantaris0low20
Pyaemia0low10
Pyemia0low10
Pyohemia0low10
Remittent Fever0low10
Renal Cancer0low10
Renal Neoplasms0low10
Retention Disorders, Cognitive0low10
Right-Sided Heart Failure0medium11
Scheie Syndrome0low10
Scheie's Syndrome0low10
Semantic Memory Disorder0low10
Senile Dementia, Acute Confusional0low60
Senile Dementia, Alzheimer Type0low60
Senile Plaques0low10
Sensitivity and Specificity0low50
Sepsis0low10
Septicemia0low10
Severe Sepsis0low10
Spatial Memory Disorder0low10
Stomach Cancer0low10
Stomach Neoplasms0low10
Streptococcal Infections0low10
Streptozocin Diabetes0low30
Streptozotocin Diabetes0low30
Thyroid Adenoma0low20
Thyroid Cancer0low20
Thyroid Carcinoma0low20
Thyroid Neoplasms0low20
Thyroid Nodule0low10
Trypanosomiasis, African0low10
Tuberculosis0low10
Tumorigenesis0low10
Tumors0low110
Tumors, Breast0low20
Tumors, Central Nervous System0low10
Type 2 Diabetes0low20
Type 2 Diabetes Mellitus0low20
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Urinary Incontinence0low10
Vascular Pseudohemophilia0low10
von Willebrand Disease0low10
von Willebrand Disease, Recessive Form0low10
von Willebrand Diseases0low10
Von Willebrand Disorder0low10
von Willebrand's Disease0low10
von Willebrand's Diseases0low10
Von Willebrand's Factor Deficiency0low10

Research Highlights

Safety/Toxicity (9)

ArticleYear
HIF-1alpha/VEGF pathway mediates 1,3,6,8-tetrabromo-9 H-carbazole-induced angiogenesis: a potential vascular toxicity of an emerging contaminant.
Journal of hazardous materials, 06-15, Volume: 432		2022
7H-Dibenzo[c,g]carbazole: Metabolic pathways and toxicity.
Chemico-biological interactions, May-25, Volume: 323		2020
Evaluation of phototoxicity of tattoo pigments using the 3 T3 neutral red uptake phototoxicity test and a 3D human reconstructed skin model.
Toxicology in vitro : an international journal published in association with BIBRA, Volume: 65		2020
Studies on interactions of carbazole derivatives with DNA, cell image, and cytotoxicity.
Bioorganic & medicinal chemistry, 01-01, Volume: 26, Issue: 1		2018
Genotoxicity of two new carbazole derivatives with antifungal activity.
Mutation research. Genetic toxicology and environmental mutagenesis, Volume: 816-817		2017
Persistence and dioxin-like toxicity of carbazole and chlorocarbazoles in soil.
Environmental science and pollution research international, Volume: 22, Issue: 2		2015
Toxicity of a polymer-graphene oxide composite against bacterial planktonic cells, biofilms, and mammalian cells.
Nanoscale, Aug-07, Volume: 4, Issue: 15		2012
In vitro metabolism and toxicity assessment of N-methylcarbazole in primary cultured rat hepatocytes.
Toxicology, Volume: 68, Issue: 3		1991
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Gliadin nanoparticles as carriers for the oral administration of lipophilic drugs. Relationships between bioadhesion and pharmacokinetics.
Pharmaceutical research, Volume: 18, Issue: 11		2001
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (2)

ArticleYear
Evaluation of phototoxicity of tattoo pigments using the 3 T3 neutral red uptake phototoxicity test and a 3D human reconstructed skin model.
Toxicology in vitro : an international journal published in association with BIBRA, Volume: 65		2020
Gliadin nanoparticles as carriers for the oral administration of lipophilic drugs. Relationships between bioadhesion and pharmacokinetics.
Pharmaceutical research, Volume: 18, Issue: 11		2001
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]