| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID143452 | Binding affinity for N-methyl-D-aspartate glutamate receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID427641 | Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor expressed in CHO cells | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. |
| AID1456726 | Inhibition of human dopamine D4.4 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID45783 | Inhibition of diltiazem binding to calcium channel | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID1456771 | Selectivity index, ratio of Ki for dopamine D3 receptor (unknown origin) to Ki for dopamine D4 receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID3844 | In vitro binding affinity to human 5-hydroxytryptamine 1A receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID63189 | Binding affinity was evaluated for the displacement of [3H]-SCH- 23390 against bovine Dopamine receptor D1 | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps. |
| AID1479868 | Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting method | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID266790 | Reduction of sc dosed 20 ug/kg 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]-pyridine-induced penile erection in Sprague-Dawley rat at 1 mg/kg, ip | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist. |
| AID61806 | Intrinsic activity as rate of incorporation of [3H]thymidine in human D4.2 receptor established in mitogenesis assay relative to quinpirole | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID198606 | Increase in plasma prolactin was determined after oral administration of a dose of 10 mg/kg; not effective | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID6598 | In vitro binding affinity to human 5-hydroxytryptamine 7 receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1456766 | Brain to plasma partition coefficient, Kp of the compound in Sprague-Dawley rat at 3 mg/kg, iv | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1456760 | Half life in Sprague-Dawley rat at 3 mg/kg, po | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID198454 | Antipsychotic potential by blockade of apomorphine or amphetamine hyperactivity. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID64965 | Binding affinity at Dopamine receptor D3 in CHO cells by radioligand displacement. | 1999 | Journal of medicinal chemistry, Dec-16, Volume: 42, Issue:25
| A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent. |
| AID1851860 | Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counting method | | | |
| AID141744 | Binding affinity to cloned Muscarinic acetylcholine receptor M3 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1526880 | Selectivity index, ratio of Ki for displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells to Ki for displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells | | | |
| AID65621 | In vitro binding affinity to cloned rat Dopamine receptor D3 measured by displacement of the radioligand [3H]sulpiride | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID65925 | Effective concentration against human Dopamine receptor D4 | 2004 | Journal of medicinal chemistry, Apr-22, Volume: 47, Issue:9
| Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. |
| AID62929 | In vitro binding affinity at human cloned dopamine receptor D2 (short) stably expressed in CHO cells by [3H]spiperone displacement. | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID198459 | Extrapyramidal liability by induction of catalepsy | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID61524 | In vitro binding affinity to cloned rat Dopamine receptor D1 measured by displacement of radioligand [3H]SCH-23,982 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID142280 | Binding affinity to cloned Muscarinic acetylcholine receptor M5 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID65921 | Intrinsic activity was measured in the human Dopamine receptor D4 calcium flux assay wiht co-transfected G-alpha-qo5 protein | 2004 | Journal of medicinal chemistry, Apr-22, Volume: 47, Issue:9
| Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. |
| AID277668 | Selectivity for dopamine D3 over dopamine D2 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID63527 | In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement. | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID29619 | Bioavailability was determined in rats | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID63531 | Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligand | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. |
| AID64179 | Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cells | 2001 | Journal of medicinal chemistry, Apr-12, Volume: 44, Issue:8
| Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapi |
| AID62911 | Binding affinity at Dopamine receptor D2 in CHO cells by radioligand displacement. | 1999 | Journal of medicinal chemistry, Dec-16, Volume: 42, Issue:25
| A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent. |
| AID1456767 | Brain to plasma partition coefficient, Kp of the compound in Sprague-Dawley rat at 3 mg/kg, po | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID156811 | Binding affinity to PCP site of rat N-methyl-D-aspartate glutamate receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID392765 | Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4
| Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups. |
| AID61626 | Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cells | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. |
| AID1456739 | Inhibition of alpha2B adrenergic receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1456729 | Inhibition of human dopamine D3 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID6481 | Binding affinity to cloned human 5-hydroxytryptamine 5A receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1526876 | Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assay | | | |
| AID1456748 | Inhibition of sigma receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID62928 | In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement. | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID198461 | Motor impairment by impaired spontaneous locomotor activity | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID1851866 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced Gi protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay | | | |
| AID1152406 | Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay | 2014 | Bioorganic & medicinal chemistry, Jun-15, Volume: 22, Issue:12
| Identification of a new selective dopamine D4 receptor ligand. |
| AID145847 | Binding affinity to cloned Nicotinic acetylcholine receptors | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID427638 | Displacement of [3H]SCH23390 from bovine dopamine D1 receptor | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. |
| AID63188 | In vitro binding affinity at human cloned dopamine receptor D1 stably expressed in CHO cells by [3H]-SCH- 23390 displacement. | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID61803 | Tested for the effective concentration against CHO 10001 cells in human D4.2 receptor established in mitogenesis assay | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID63055 | Binding affinity towards cloned human Dopamine receptor D2 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligand | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. |
| AID63065 | Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cells | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Isoindolinone enantiomers having affinity for the dopamine D4 receptor. |
| AID1456738 | Inhibition of alpha2A adrenergic receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID152070 | Binding affinity to cloned Opioid receptor mu 1 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID5144 | Inhibitory activity against cloned human 5-HT2 receptor | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. |
| AID427639 | Displacement of [3H]SCH23390 from human cloned dopamine D2 long receptor expressed in CHO cells | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. |
| AID219083 | IKr activity in ferret papillary muscle | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID65731 | In vitro binding affinity to rat Dopamine receptor D2 measured by displacement of the radioligand [3H]spiperone | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID87679 | Binding affinity to cloned Histamine H1 receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID142019 | Binding affinity to cloned Muscarinic acetylcholine receptor M4 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID63665 | In vitro binding affinity to human Dopamine receptor D4 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID63219 | In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]spiroperidol as radioligand. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand. |
| AID63535 | In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement. | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Isoindolinone enantiomers having affinity for the dopamine D4 receptor. |
| AID427642 | Displacement of [3H]spiroperidol from human cloned dopamine D4.4 receptor expressed in CHO cells | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. |
| AID1456728 | Inhibition of human dopamine D2 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID148713 | Binding affinity to cloned Opioid receptor kappa 1 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID5871 | Binding affinity to cloned human 5-hydroxytryptamine 2C receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID64993 | Binding affinity towards cloned human Dopamine receptor D3 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligand | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. |
| AID1152403 | Displacement of [3H]SCH23390 from human dopamine D1 receptor by PDSP assay | 2014 | Bioorganic & medicinal chemistry, Jun-15, Volume: 22, Issue:12
| Identification of a new selective dopamine D4 receptor ligand. |
| AID266791 | Reduction of icv dosed 1 ug 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]-pyridine-induced penile erection in Sprague-Dawley rat at 1 mg/kg, ip | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist. |
| AID1456755 | Inhibition of human dopamine D4 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID29620 | Bioavailability was determined in rhesus monkey | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID4241 | Binding affinity to cloned human 5-hydroxytryptamine 1B receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID4948 | Binding affinity to cloned human 5-hydroxytryptamine 1E receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1456741 | Inhibition of alpha1C adrenergic receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID64991 | In vitro binding affinity at human cloned dopamine receptor D3 stably expressed in CHO cells by [3H]spiperone displacement. | 2002 | Bioorganic & medicinal chemistry letters, Feb-25, Volume: 12, Issue:4
| Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. |
| AID1479889 | Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced RLuc8-fused Galphai1 activation preincubated for 15 mins followed by dopamine induction measured after 2 mins by | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID1456763 | Half life in rhesus monkey at 1 mg/kg, iv | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1851867 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced beta arrestin-2 recruitment pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay | | | |
| AID1851861 | Displacement of [3H]N-methylspiperone from human D3R receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counting method | | | |
| AID1526875 | Displacement of [3H] Spiperone from human D2L receptor expressed in CHO cells by competitive radioligand binding assay | | | |
| AID63543 | Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement; Not active. | 2000 | Bioorganic & medicinal chemistry letters, Sep-18, Volume: 10, Issue:18
| Design, synthesis, and discovery of 3-piperazinyl-3,4-dihydro-2(1H)-quinolinone derivatives: a novel series of mixed dopamine D2/D4 receptor antagonists. |
| AID1456732 | Inhibition of serotonin 5-HT2 receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID63667 | In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]YM-09151-2 as radioligand. | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand. |
| AID1526878 | Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay | | | |
| AID1456772 | Selectivity index, ratio of Ki for dopamine D5 receptor (unknown origin) to Ki for dopamine D4 receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1456731 | Inhibition of serotonin 5-HT1A receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1851868 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced G0 protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay relative to contro | | | |
| AID1479871 | Selectivity ratio of Ki for human dopamine D2 receptor to Ki for human dopamine D4 receptor | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID63528 | Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement. | 2004 | Journal of medicinal chemistry, Apr-22, Volume: 47, Issue:9
| Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. |
| AID5193 | Binding affinity to cloned human 5-hydroxytryptamine 2A receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1851863 | Selectivity ratio of pKi for displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cell membrane to pKi for displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane | | | |
| AID198601 | EPS liability measured by blockade of stereotypy at a oral administration of 1 mg/kg; not effective | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID198460 | Motor impairment by impaired rotarod performance. | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID1851869 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced Gi protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay relative to contro | | | |
| AID198462 | Antipsychotic potential by blockade of apomorphine disruption in PPI at a oral administration of 1 mg/kg; not effective | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID63835 | In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]spiperone | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID427640 | Displacement of [3H]spiroperidol from human cloned dopamine D2 short receptor expressed in CHO cells | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13
| Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. |
| AID1456765 | Oral bioavailability in rhesus monkey at 1 mg/kg | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1479891 | Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced mVenus-fused beta-arrestin2 recruitment preincubated for 15 mins followed by dopamine induction measured after 2 | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID61782 | Ability to displace [3H]spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cells | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. |
| AID1851862 | Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counting method | | | |
| AID277669 | Selectivity for dopamine D3 over dopamine D4 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID65120 | Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cells | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Isoindolinone enantiomers having affinity for the dopamine D4 receptor. |
| AID229201 | Binding affinity towards sigma receptor was determined | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID232502 | Selectivity ratio of D2 receptor to that of D4 receptor | 2004 | Journal of medicinal chemistry, Apr-22, Volume: 47, Issue:9
| Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. |
| AID27018 | Half lif period in both rats and rhesus monkey | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID277674 | Displacement of [3H]spiperone from human dopamine D4.4 expressed in CHO cell membrane | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID140944 | Binding affinity to cloned Muscarinic acetylcholine receptor M2 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1152405 | Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by PDSP assay | 2014 | Bioorganic & medicinal chemistry, Jun-15, Volume: 22, Issue:12
| Identification of a new selective dopamine D4 receptor ligand. |
| AID1152407 | Displacement of [3H]SCH23390 from human dopamine D5 receptor by PDSP assay | 2014 | Bioorganic & medicinal chemistry, Jun-15, Volume: 22, Issue:12
| Identification of a new selective dopamine D4 receptor ligand. |
| AID4624 | In vitro binding affinity to human 5-hydroxytryptamine 1D receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1479870 | Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting method | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID1526881 | Selectivity index, ratio of Ki for displacement of [3H] Spiperone from human D3 receptor expressed in CHO cells to Ki for displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells | | | |
| AID1456762 | Half life in rhesus monkey at 1 mg/kg, po | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1456764 | Oral bioavailability in Sprague-Dawley rat at 3 mg/kg | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1479869 | Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting method | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID1851864 | Selectivity ratio of pKi for displacement of [3H]N-methylspiperone from human D3R expressed in HEK293T cell membrane to pKi for displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane | | | |
| AID198599 | Antipsychotic potential by inhibition of conditioned avoidance responding at a oral administration of 1 mg/kg; not effective | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID5015 | Binding affinity towards 5-hydroxytryptamine 2 receptor was determined | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID1479872 | Selectivity ratio of Ki for human dopamine D3 receptor to Ki for human dopamine D4 receptor | 2018 | Journal of medicinal chemistry, 04-26, Volume: 61, Issue:8
| 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D |
| AID1152404 | Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by PDSP assay | 2014 | Bioorganic & medicinal chemistry, Jun-15, Volume: 22, Issue:12
| Identification of a new selective dopamine D4 receptor ligand. |
| AID1851865 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced G0 protein activation pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay | | | |
| AID150091 | Binding affinity to cloned Opioid receptor delta 1 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1456740 | Inhibition of alpha2C adrenergic receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID393002 | Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4
| Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups. |
| AID63519 | Binding affinity evaluated for the displacement of [3H]spiperone against human dopamine receptor D4 | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps. |
| AID62331 | Binding affinity was evaluated for the displacement of [3H]spiperone against bovine Dopamine receptor D2 | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps. |
| AID6526 | In vitro binding affinity to human 5-hydroxytryptamine 6 receptor | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID61309 | Ability to displace [3H]spiperone from cloned human dopamine D2 receptor stably expressed in CHO cells | 1999 | Bioorganic & medicinal chemistry letters, Feb-22, Volume: 9, Issue:4
| Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. |
| AID1526877 | Displacement of [3H] Spiperone from human D3 receptor expressed in CHO cells by competitive radioligand binding assay | | | |
| AID1456727 | Inhibition of human dopamine D1 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID65953 | Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement. | 1999 | Journal of medicinal chemistry, Dec-16, Volume: 42, Issue:25
| A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent. |
| AID1456730 | Inhibition of human dopamine D5 receptor | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID1456761 | Half life in Sprague-Dawley rat at 3 mg/kg, iv | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID277677 | Binding affinity to dopamine D2 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID63080 | Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement; Not active. | 2000 | Bioorganic & medicinal chemistry letters, Sep-18, Volume: 10, Issue:18
| Design, synthesis, and discovery of 3-piperazinyl-3,4-dihydro-2(1H)-quinolinone derivatives: a novel series of mixed dopamine D2/D4 receptor antagonists. |
| AID141970 | Binding affinity to cloned Muscarinic acetylcholine receptor M1 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID64189 | In vitro binding affinity to cloned rat D5 receptor measured by displacement of radioligand [3H]SCH-23,982 | 2001 | Bioorganic & medicinal chemistry letters, Jun-04, Volume: 11, Issue:11
| Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. |
| AID1456769 | Selectivity index, ratio of Ki for dopamine D1 receptor (unknown origin) to Ki for dopamine D4 receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID277673 | Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membrane | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID1456742 | Inhibition of alpha1B adrenergic receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID62931 | Binding affinity against human Dopamine receptor D2 using [3H]spiperone as radioligand | 2004 | Journal of medicinal chemistry, Apr-22, Volume: 47, Issue:9
| Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. |
| AID1851870 | Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced beta arrestin-2 recruitment pretreated for 10 mins followed by dopamine addition and measured after 2.5 mins by BRET assay relative to | | | |
| AID63537 | Binding affinity towards human dopamine receptor D4 | 2001 | Journal of medicinal chemistry, Feb-15, Volume: 44, Issue:4
| Current and novel approaches to the drug treatment of schizophrenia. |
| AID64980 | Binding affinity evaluated for the displacement of [3H]-spiperone against human dopamine receptor D3 | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps. |
| AID1526879 | Selectivity index, ratio of Ki for displacement of [3H] Spiperone from human D2L receptor expressed in CHO cells to Ki for displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells | | | |
| AID233385 | It is the ratio of binding affinity of D2 receptor to that of D4 receptor | 1998 | Journal of medicinal chemistry, Nov-19, Volume: 41, Issue:24
| N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand. |
| AID1456770 | Selectivity index, ratio of Ki for dopamine D2 receptor (unknown origin) to Ki for dopamine D4 receptor (unknown origin) | 2017 | Journal of medicinal chemistry, 09-14, Volume: 60, Issue:17
| Return of D |
| AID588349 | qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay | | | |
| AID1347045 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID588378 | qHTS for Inhibitors of ATXN expression: Validation | | | |
| AID1347410 | qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library | 2019 | Cellular signalling, 08, Volume: 60 | A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening. |
| AID1347059 | CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347049 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1347058 | CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347057 | CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347405 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347050 | Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID504836 | Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation | 2002 | The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. |
| AID1347151 | Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID1345814 | Human D4 receptor (Dopamine receptors) | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |