topotecan has been researched along with Sensitivity and Specificity in 19 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (15.79) | 18.2507 |
2000's | 12 (63.16) | 29.6817 |
2010's | 4 (21.05) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bai, F; Fraga, CH; Hubbard, KE; Miller, L; Panetta, JC; Schaiquevich, P; Stewart, CF | 1 |
Arellano, C; Bettuing, L; Chatelut, E; Gandia, P; Woodley, J | 1 |
Aucélio, RQ; da Cunha, AL; Marques, FF | 1 |
Chang, QY; Li, M; Li, XG; Li, YF; Liu, J; Song, PP; Tian, HM; Wang, XB; Wu, LY; Zhang, W; Zhao, D | 1 |
Ingebrandt, S; Koppenhöfer, D; Susloparova, A; Vu, XT; Weil, M | 1 |
Nyormoi, O; Satoh, TH; Surmacz, TA; Whitacre, CM | 1 |
Lane, SR; Ross, GA; ten Bokkel Huinink, W | 1 |
Daw, NC; Furman, WL; Gajjar, AJ; Hawkins, DR; Houghton, PJ; Iacono, LC; Panetta, JC; Santana, VM; Stewart, CF | 1 |
Balthasar, JP; Chen, J | 1 |
Dadashzadeh, S; Shafaghi, B; Vali, AM | 1 |
Beijnen, JH; Buckle, T; de Vries, NA; Ouwehand, M; van Tellingen, O | 1 |
Bansal, T; Jaggi, M; Khar, RK; Mishra, G; Mukherjee, R; Singh, M; Talegaonkar, S | 1 |
Kim, K | 1 |
Loos, WJ; Schellens, JH; Stoter, G; Verweij, J | 1 |
Ardizzoni, A; de Cupis, A; Favoni, RE; Grossi, F; Loprevite, M; Merlo, F; Pirani, P | 1 |
Huang, J; Kandel, JJ; Kim, E; Manley, C; Middlesworth, W; Moore, JT; O'Toole, K; Soffer, SZ; Stolar, C; Yamashiro, DJ; Yokoi, A | 1 |
Apan, A; Bayar, N; Böke, B; Koç, MC | 1 |
Bakr, M; Bauer, J; Bodmer, A; Duvoisin, B; Ketterer, N; Leyvraz, S; Perey, L; Stupp, R | 1 |
Gelderblom, H; Loos, WJ; Nooter, K; Sparreboom, A; Stoter, G; van Zomeren, DM; Verweij, J | 1 |
3 trial(s) available for topotecan and Sensitivity and Specificity
Article | Year |
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Long-term survival in a phase III, randomised study of topotecan versus paclitaxel in advanced epithelial ovarian carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Disease Progression; Drug Administration Schedule; Female; Humans; Incidence; Infusions, Intravenous; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Quality of Life; Sensitivity and Specificity; Survival Analysis; Topotecan | 2004 |
Phase I and pharmacokinetic study of topotecan administered orally once daily for 5 days for 2 consecutive weeks to pediatric patients with refractory solid tumors.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Maximum Tolerated Dose; Neoplasms; Salvage Therapy; Sampling Studies; Sensitivity and Specificity; Topotecan; Treatment Outcome | 2004 |
Is cisplatin required for the treatment of non-small-cell lung cancer? Experience and preliminary results of a phase I/II trial with topotecan and vinorelbine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Sensitivity and Specificity; Survival Rate; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine | 2001 |
16 other study(ies) available for topotecan and Sensitivity and Specificity
Article | Year |
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Application of a highly specific and sensitive fluorescent HPLC method for topotecan lactone in whole blood.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Linear Models; Methanol; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Spectrometry, Fluorescence; Topotecan | 2009 |
Quantification of topotecan by liquid chromatography-mass spectrometry (LC-MS). Application to intestinal transport using rat everted gut sacs.
Topics: Animals; Antiemetics; Antineoplastic Agents; Chromatography, Liquid; Drug Interactions; Duodenum; Hydrogen-Ion Concentration; Least-Squares Analysis; Male; Mass Spectrometry; Models, Biological; Ondansetron; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Topotecan | 2010 |
Laser induced fluorescence and photochemical derivatization for trace determination of camptothecin.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Fluorescence; Irinotecan; Lasers; Pharmaceutical Preparations; Photochemistry; Sensitivity and Specificity; Spectrometry, Fluorescence; Topotecan | 2010 |
[Application of ATP-tumor chemosensitivity assay in recurrent epithelial ovarian cancer].
Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; CA-125 Antigen; Carcinoma, Endometrioid; Cystadenocarcinoma, Serous; Deoxycytidine; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Follow-Up Studies; Gemcitabine; Humans; Luminescent Measurements; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Survival Rate; Topotecan | 2010 |
Impedance spectroscopy with field-effect transistor arrays for the analysis of anti-cancer drug action on individual cells.
Topics: Antineoplastic Agents; Apoptosis; Biosensing Techniques; Cell Line, Tumor; Cell Separation; Cell Survival; Dielectric Spectroscopy; Drug Evaluation, Preclinical; Equipment Design; Equipment Failure Analysis; Flow Cytometry; Humans; Neoplasms, Experimental; Reproducibility of Results; Sensitivity and Specificity; Topotecan; Transistors, Electronic; Treatment Outcome | 2013 |
Inhibition of focal adhesion kinase by antisense oligonucleotides enhances the sensitivity of breast cancer cells to camptothecins.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Camptothecin; Caspase 3; Caspase 9; Caspases; Cell Adhesion; Enzyme Activation; Enzyme Precursors; Female; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides, Antisense; Poly(ADP-ribose) Polymerases; Protein-Tyrosine Kinases; Sensitivity and Specificity; Topotecan; Tumor Cells, Cultured; Tumor Protein, Translationally-Controlled 1 | 2003 |
High-performance liquid chromatographic assay for the determination of total and free topotecan in the presence and absence of anti-topotecan antibodies in mouse plasma.
Topics: Animals; Antibodies; Antineoplastic Agents; Chromatography, High Pressure Liquid; Mice; Mice, Inbred BALB C; Reproducibility of Results; Sensitivity and Specificity; Topotecan | 2005 |
Simple and sensitive high performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of topotecan in human plasma.
Topics: Carboxylic Acids; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lactones; Reproducibility of Results; Sensitivity and Specificity; Topotecan | 2005 |
Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Stability; Feasibility Studies; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Spectrometry, Fluorescence; Tissue Distribution; Topotecan | 2007 |
Concurrent determination of topotecan and model permeability markers (atenolol, antipyrine, propranolol and furosemide) by reversed phase liquid chromatography: utility in Caco-2 intestinal absorption studies.
Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Chromatography, High Pressure Liquid; Drug Stability; Furosemide; Humans; Intestinal Absorption; Permeability; Propranolol; Reproducibility of Results; Sensitivity and Specificity; Topotecan | 2007 |
SEQPWR and SEQOPR: computer programs for design of maximum information trials based on group sequential logrank tests.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Data Interpretation, Statistical; Etoposide; Feasibility Studies; Follow-Up Studies; Humans; Linear Models; Lung Neoplasms; Programming Languages; Research Design; Sensitivity and Specificity; Software; Survival Rate; Topotecan | 1995 |
Sensitive high-performance liquid chromatographic fluorescence assay for the quantitation of topotecan (SKF 104864-A) and its lactone ring-opened product (hydroxy acid) in human plasma and urine.
Topics: Camptothecin; Chromatography, High Pressure Liquid; Drug Stability; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hydroxy Acids; Kinetics; Regression Analysis; Sensitivity and Specificity; Topoisomerase I Inhibitors; Topotecan | 1996 |
Pre-clinical evaluation of new antineoplastic agents in NSCLC cell lines: evidence of histological subtype-dependent cytotoxicity.
Topics: Adenocarcinoma; Antineoplastic Agents; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cisplatin; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Inhibitory Concentration 50; Irinotecan; Lung Neoplasms; Paclitaxel; Sensitivity and Specificity; Taxoids; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 1999 |
Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Disease Models, Animal; Endothelial Growth Factors; In Situ Nick-End Labeling; Injections, Intraperitoneal; Kidney Neoplasms; Lymphokines; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Reference Values; Sensitivity and Specificity; Survival Rate; Topotecan; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wilms Tumor | 2001 |
Efficacy of topotecan treatment on an experimental model of transient evoked otoacoustic emissions.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intravenous; Male; Models, Animal; Otoacoustic Emissions, Spontaneous; Probability; Rabbits; Sensitivity and Specificity; Statistics, Nonparametric; Topotecan | 2001 |
Determination of topotecan in human whole blood and unwashed erythrocytes by high-performance liquid chromatography.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Topotecan | 2002 |