Proteins > apical membrane antigen 1, AMA1
Page last updated: 2024-08-07 22:48:45

apical membrane antigen 1, AMA1

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (1514)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
dinitrochlorobenzenePlasmodium falciparum 3D7Potency39.810710
cysteine sulfinic acidPlasmodium falciparum 3D7Potency15.848910
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoic acidPlasmodium falciparum 3D7Potency3.162310
3,4-dihydroxyphenylacetic acidPlasmodium falciparum 3D7Potency8.912510
histaminePlasmodium falciparum 3D7Potency5.011910
2,2'-dipyridylPlasmodium falciparum 3D7Potency4.466810
2-aminofluorenePlasmodium falciparum 3D7Potency15.848910
pyrithionePlasmodium falciparum 3D7Potency28.183810
3,4-dichloroisocoumarinPlasmodium falciparum 3D7Potency39.810710
ethylisopropylamiloridePlasmodium falciparum 3D7Potency10.000010
6-hydroxymelatoninPlasmodium falciparum 3D7Potency4.466810
tyrphostin a23Plasmodium falciparum 3D7Potency10.000010
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolPlasmodium falciparum 3D7Potency11.220210
benzo(a)pyrenePlasmodium falciparum 3D7Potency15.848910
butylbenzyl phthalatePlasmodium falciparum 3D7Potency28.183810
busulfanPlasmodium falciparum 3D7Potency39.810710
camphor, (+-)-isomerPlasmodium falciparum 3D7Potency8.912510
3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7-[[1-oxo-2-(1-tetrazolyl)ethyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidPlasmodium falciparum 3D7Potency39.810710
deferipronePlasmodium falciparum 3D7Potency19.952610
deferoxaminePlasmodium falciparum 3D7Potency1.412510
disulfiramPlasmodium falciparum 3D7Potency14.125410
embelinPlasmodium falciparum 3D7Potency39.810710
epirizolePlasmodium falciparum 3D7Potency25.118910
myambutolPlasmodium falciparum 3D7Potency3.981110
ethionPlasmodium falciparum 3D7Potency22.387210
ethoxyquinPlasmodium falciparum 3D7Potency22.387210
etidronatePlasmodium falciparum 3D7Potency3.548110
fipexidePlasmodium falciparum 3D7Potency12.589310
fluconazolePlasmodium falciparum 3D7Potency3.162310
beta-thujaplicinPlasmodium falciparum 3D7Potency39.810710
iodoquinolPlasmodium falciparum 3D7Potency1.778310
lansoprazolePlasmodium falciparum 3D7Potency12.589310
mitoxantronePlasmodium falciparum 3D7Potency10.000010
nadifloxacinPlasmodium falciparum 3D7Potency31.622810
nialamidePlasmodium falciparum 3D7Potency17.782810
nisoldipinePlasmodium falciparum 3D7Potency14.125410
masoprocolPlasmodium falciparum 3D7Potency7.079510
omeprazolePlasmodium falciparum 3D7Potency19.952610
oxeladinPlasmodium falciparum 3D7Potency28.183810
oxethazainePlasmodium falciparum 3D7Potency3.162310
penicillin vPlasmodium falciparum 3D7Potency25.118910
perphenazinePlasmodium falciparum 3D7Potency31.622810
ppm 18Plasmodium falciparum 3D7Potency14.125410
prochlorperazinePlasmodium falciparum 3D7Potency15.848910
protoporphyrin ixPlasmodium falciparum 3D7Potency4.466810
silymarinPlasmodium falciparum 3D7Potency28.183810
sobuzoxanePlasmodium falciparum 3D7Potency3.548110
streptonigrinPlasmodium falciparum 3D7Potency39.810710
sulfaguanidinePlasmodium falciparum 3D7Potency3.162310
thiramPlasmodium falciparum 3D7Potency3.548110
tolnaftatePlasmodium falciparum 3D7Potency39.810710
trifluoperazinePlasmodium falciparum 3D7Potency11.220210
isoproterenol hydrochloridePlasmodium falciparum 3D7Potency31.622810
thyroxinePlasmodium falciparum 3D7Potency3.162310
azauridinePlasmodium falciparum 3D7Potency39.810710
triiodothyroninePlasmodium falciparum 3D7Potency1.258910
methyldimethylaminoazobenzenePlasmodium falciparum 3D7Potency15.848910
9,10-dimethyl-1,2-benzanthracenePlasmodium falciparum 3D7Potency17.782810
levodopaPlasmodium falciparum 3D7Potency14.125410
p-aminoazobenzenePlasmodium falciparum 3D7Potency11.220210
yohimbine hydrochloridePlasmodium falciparum 3D7Potency0.891310
ampicillinPlasmodium falciparum 3D7Potency2.818410
perthanePlasmodium falciparum 3D7Potency28.183810
chlorquinaldolPlasmodium falciparum 3D7Potency1.778310
n,n'-diphenyl-4-phenylenediaminePlasmodium falciparum 3D7Potency15.848910
1-amino-2-methylanthraquinonePlasmodium falciparum 3D7Potency22.387210
disperse red 9Plasmodium falciparum 3D7Potency3.981110
diphenyl phthalatePlasmodium falciparum 3D7Potency25.118910
1-phenylazo-2-naphthylaminePlasmodium falciparum 3D7Potency17.782810
1-(2-pyridylazo)-2-naphtholPlasmodium falciparum 3D7Potency10.000010
uvitex swnPlasmodium falciparum 3D7Potency22.387210
2-naphthylaminePlasmodium falciparum 3D7Potency35.481310
pyroninePlasmodium falciparum 3D7Potency22.387210
dehydrothio-4-toluidinePlasmodium falciparum 3D7Potency3.981110
phenothiazinePlasmodium falciparum 3D7Potency35.481310
n,n-diethyl 4-phenylenediaminePlasmodium falciparum 3D7Potency11.220210
2,4-d n-butyl esterPlasmodium falciparum 3D7Potency25.118910
o-aminoazotoluenePlasmodium falciparum 3D7Potency11.220210
methyl gallatePlasmodium falciparum 3D7Potency1.258910
4-aminodiphenylaminePlasmodium falciparum 3D7Potency37.685810
n,n,n',n'-tetramethyl-4,4'-methylenedianilinePlasmodium falciparum 3D7Potency14.125410
n-isopropyl-n-phenyl-4-phenylenediaminePlasmodium falciparum 3D7Potency39.810710
1-amino-4-hydroxyanthraquinonePlasmodium falciparum 3D7Potency7.079510
benzyl salicylatePlasmodium falciparum 3D7Potency28.183810
maltolPlasmodium falciparum 3D7Potency4.466810
dibenzoylmethanePlasmodium falciparum 3D7Potency15.848910
sulfan bluePlasmodium falciparum 3D7Potency15.848910
tonessPlasmodium falciparum 3D7Potency15.848910
2-Phenylethyl 2-aminobenzoatePlasmodium falciparum 3D7Potency22.387210
phenazopyridine hydrochloridePlasmodium falciparum 3D7Potency28.183810
2-aminobenzothiazolePlasmodium falciparum 3D7Potency0.631010
chelidamic acidPlasmodium falciparum 3D7Potency0.422810
nitrilotriacetic acidPlasmodium falciparum 3D7Potency0.891310
protocatechualdehydePlasmodium falciparum 3D7Potency14.125410
fluoranthenePlasmodium falciparum 3D7Potency25.118910
benz(c)acridinePlasmodium falciparum 3D7Potency28.183810
aminoimidazole carboxamidePlasmodium falciparum 3D7Potency28.183810
rheinPlasmodium falciparum 3D7Potency28.183810
cepharanthinePlasmodium falciparum 3D7Potency19.952610
flavanonePlasmodium falciparum 3D7Potency14.125410
2,4-pyridinedicarboxylic acidPlasmodium falciparum 3D7Potency23.778110
hematoxylinPlasmodium falciparum 3D7Potency1.995310
dazometPlasmodium falciparum 3D7Potency17.782810
nitrophenidePlasmodium falciparum 3D7Potency12.589310
neutral red basePlasmodium falciparum 3D7Potency2.818410
3-hydroxyflavonePlasmodium falciparum 3D7Potency39.810710
adipic acid dicyclohexyl esterPlasmodium falciparum 3D7Potency22.387210
n-acetylmelphalanPlasmodium falciparum 3D7Potency29.934910
2,2'-dipyridylaminePlasmodium falciparum 3D7Potency12.589310
2-amino-4-phenylphenolPlasmodium falciparum 3D7Potency31.622810
pimozidePlasmodium falciparum 3D7Potency31.622810
7-hydroxychlorpromazinePlasmodium falciparum 3D7Potency19.952610
1-methylpyrenePlasmodium falciparum 3D7Potency31.622810
ethyl violetPlasmodium falciparum 3D7Potency2.238710
1,2-dibromo-4-(1,2-dibromoethyl)cyclohexanePlasmodium falciparum 3D7Potency25.118910
Bis(2-furanylmethyl) disulfidePlasmodium falciparum 3D7Potency25.118910
u 0521Plasmodium falciparum 3D7Potency31.622810
cyclophosphamidePlasmodium falciparum 3D7Potency7.943310
psoromic acidPlasmodium falciparum 3D7Potency1.122010
2-bromo-N-phenylbenzamidePlasmodium falciparum 3D7Potency6.309610
salenPlasmodium falciparum 3D7Potency6.309610
benserazide hydrochloridePlasmodium falciparum 3D7Potency7.943310
gidifenPlasmodium falciparum 3D7Potency8.912510
metergolinePlasmodium falciparum 3D7Potency31.622810
razoxanePlasmodium falciparum 3D7Potency22.387210
silybinPlasmodium falciparum 3D7Potency14.125410
hoe-40045Plasmodium falciparum 3D7Potency19.952610
9-chloromethylanthracenePlasmodium falciparum 3D7Potency6.309610
cefazolinPlasmodium falciparum 3D7Potency35.481310
amoxicillinPlasmodium falciparum 3D7Potency2.238710
carbidopaPlasmodium falciparum 3D7Potency3.548110
methyldopaPlasmodium falciparum 3D7Potency11.220210
ciclopirox olaminePlasmodium falciparum 3D7Potency3.548110
permethrinPlasmodium falciparum 3D7Potency28.183810
flecainide acetatePlasmodium falciparum 3D7Potency4.466810
3,3',5,5'-tetramethylbenzidinePlasmodium falciparum 3D7Potency25.118910
FlampropPlasmodium falciparum 3D7Potency8.912510
cefadroxil anhydrousPlasmodium falciparum 3D7Potency15.848910
fenoldopam mesylatePlasmodium falciparum 3D7Potency12.589310
avobenzonePlasmodium falciparum 3D7Potency11.220210
mifepristonePlasmodium falciparum 3D7Potency14.125410
topotecan hydrochloridePlasmodium falciparum 3D7Potency25.118910
Phenylmethyl benzeneacetatePlasmodium falciparum 3D7Potency31.622810
ep 201Plasmodium falciparum 3D7Potency19.952610
Eugenyl benzoatePlasmodium falciparum 3D7Potency31.622810
paroxetine hydrochloridePlasmodium falciparum 3D7Potency22.387210
desferrioxamine b mesylatePlasmodium falciparum 3D7Potency1.258910
ro 5-3335Plasmodium falciparum 3D7Potency28.183810
2,2'-dipyridyl disulfidePlasmodium falciparum 3D7Potency39.810710
neocuproinePlasmodium falciparum 3D7Potency15.848910
dobutamine hydrochloridePlasmodium falciparum 3D7Potency10.000010
dopamine hydrochloridePlasmodium falciparum 3D7Potency3.548110
epirubicin hydrochloridePlasmodium falciparum 3D7Potency6.309610
sufentanil citratePlasmodium falciparum 3D7Potency7.079510
thioridazine hydrochloridePlasmodium falciparum 3D7Potency31.622810
salicylhydroxamic acidPlasmodium falciparum 3D7Potency8.912510
thionalidePlasmodium falciparum 3D7Potency3.981110
dibenzthionePlasmodium falciparum 3D7Potency19.952610
dabiPlasmodium falciparum 3D7Potency3.162310
dimidium bromidePlasmodium falciparum 3D7Potency35.481310
cefaloramPlasmodium falciparum 3D7Potency7.079510
5-nitroisoquinolinePlasmodium falciparum 3D7Potency0.316210
5-fluoroorotic acidPlasmodium falciparum 3D7Potency31.622810
2,3,4-trihydroxbenzophenonePlasmodium falciparum 3D7Potency12.589310
talampicillin hydrochloridePlasmodium falciparum 3D7Potency1.412510
2,2'-((3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)diimino)bis-benzoic acidPlasmodium falciparum 3D7Potency17.782810
coumarin 153Plasmodium falciparum 3D7Potency12.589310
3-hydroxy naphthoic acid hydrazidePlasmodium falciparum 3D7Potency2.818410
berberrubinePlasmodium falciparum 3D7Potency4.466810
methyl fluorone blackPlasmodium falciparum 3D7Potency2.377810
9-hydroxyphenylfluoronPlasmodium falciparum 3D7Potency1.122010
5-nitro-1,10-phenanthrolinePlasmodium falciparum 3D7Potency3.548110
1,10-phenanthroline-5,6-dionePlasmodium falciparum 3D7Potency2.818410
2,6-diphenylpyridinePlasmodium falciparum 3D7Potency39.810710
methylene violetPlasmodium falciparum 3D7Potency7.943310
2-chloranilPlasmodium falciparum 3D7Potency25.118910
ergocorninePlasmodium falciparum 3D7Potency39.810710
fangchinolinePlasmodium falciparum 3D7Potency14.125410
stictic acidPlasmodium falciparum 3D7Potency25.118910
8-hydroxy-2-quinolinecarboxylic acidPlasmodium falciparum 3D7Potency3.548110
2-phenylisatogenPlasmodium falciparum 3D7Potency12.589310
4-(2-thiazolylazo)resorcinolPlasmodium falciparum 3D7Potency1.122010
ethyl isodehydracetatePlasmodium falciparum 3D7Potency6.309610
2,4,6-tripyridyl-s-triazinePlasmodium falciparum 3D7Potency6.309610
3-amino-1-phenyl-4,5-dihydro-1h-pyrazol-5-onePlasmodium falciparum 3D7Potency6.309610
n-benzyl-4-toluidinePlasmodium falciparum 3D7Potency10.000010
2-(1H-benzimidazol-2-yl)anilinePlasmodium falciparum 3D7Potency39.810710
N,N'-bis(3-methylphenyl)ethane-1,2-diaminePlasmodium falciparum 3D7Potency22.387210
8-(4-tolylsulfonylamino)quinolinePlasmodium falciparum 3D7Potency2.511910
2-butyl-6-(butylamino)-1h-benzo(de)isoquinoline-1,3(2h)-dionePlasmodium falciparum 3D7Potency14.125410
7-(diethylamino)-1-benzopyran-2-onePlasmodium falciparum 3D7Potency31.622810
1-(10-methyl-2-phenothiazinyl)ethanonePlasmodium falciparum 3D7Potency39.810710
sennoside BPlasmodium falciparum 3D7Potency1.412510
nipecotic acid amidePlasmodium falciparum 3D7Potency17.782810
1-(2-thiazolylazo)-2-naphtholPlasmodium falciparum 3D7Potency28.183810
judaicin (eudesmane naphthofuran)Plasmodium falciparum 3D7Potency3.981110
coumarin 7Plasmodium falciparum 3D7Potency6.309610
bnps-skatolePlasmodium falciparum 3D7Potency14.125410
3-(n-salicyloyl)amino-1,2,4-triazolePlasmodium falciparum 3D7Potency14.125410
2,2',4,4'-tetrabromodiphenyl etherPlasmodium falciparum 3D7Potency25.118910
9,10-phenanthrenequinone monoximePlasmodium falciparum 3D7Potency3.162310
n',n'-dibenzylbenzohydrazidePlasmodium falciparum 3D7Potency39.810710
4-chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acidPlasmodium falciparum 3D7Potency1.412510
4,4'-ethylenebis(1-methyl-2,6-piperazinedione)Plasmodium falciparum 3D7Potency7.943310
3,3'-DihydroxyhexestrolPlasmodium falciparum 3D7Potency25.118910
6,6'-methylene bis(2,2,4-trimethyl-1,2-dihydroquinoline)Plasmodium falciparum 3D7Potency15.848910
hydroperoxyisophosphamidePlasmodium falciparum 3D7Potency27.095510
2-(3'-methoxy-4'-hydroxybenzylidene)cyclopentene-1,3-dionePlasmodium falciparum 3D7Potency11.220210
1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanolPlasmodium falciparum 3D7Potency14.125410
cyanonaphthyridinomycinPlasmodium falciparum 3D7Potency39.810710
3-chloro-6-hydrazino-pyridazinePlasmodium falciparum 3D7Potency39.810710
2,5-dihydro-2-(4-methoxyphenyl)-3h-pyrazolo(4,3-c)quinolin-3-onePlasmodium falciparum 3D7Potency7.079510
moxifloxacin hydrochloridePlasmodium falciparum 3D7Potency44.668410
s-nitrosoglutathionePlasmodium falciparum 3D7Potency1.778310
sudan yellow 3gPlasmodium falciparum 3D7Potency3.162310
tanshinonePlasmodium falciparum 3D7Potency12.589310
pivmecillinam hydrochloridePlasmodium falciparum 3D7Potency7.943310
1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanolPlasmodium falciparum 3D7Potency28.183810
histamine dihydrochloridePlasmodium falciparum 3D7Potency12.589310
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidPlasmodium falciparum 3D7Potency8.912510
nifekalant hydrochloridePlasmodium falciparum 3D7Potency2.511910
angiotensin ii, des-asp(1)-des-arg(2)-ile(5)-Plasmodium falciparum 3D7Potency17.782810
alpha-(n6-adenyl)styrene oxidePlasmodium falciparum 3D7Potency31.622810
n-succinyldesferrioxamine bPlasmodium falciparum 3D7Potency1.584910
n-(6-methoxy-8-quinolyl)-4-toluenesulfonamidePlasmodium falciparum 3D7Potency2.511910
pyrophenPlasmodium falciparum 3D7Potency12.589310
umifenovirPlasmodium falciparum 3D7Potency28.183810
tilarginine acetatePlasmodium falciparum 3D7Potency35.481310
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomerPlasmodium falciparum 3D7Potency7.943310
5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavonePlasmodium falciparum 3D7Potency15.848910
3-methyl-1,3-benzoxazole-2-thionePlasmodium falciparum 3D7Potency1.412510
8-(methylsulfonylamino)quinolinePlasmodium falciparum 3D7Potency31.622810
idazoxan hydrochloridePlasmodium falciparum 3D7Potency14.125410
sch 45752Plasmodium falciparum 3D7Potency7.079510
oxidopamine hydrochloridePlasmodium falciparum 3D7Potency0.794310
cryptotanshinonePlasmodium falciparum 3D7Potency28.183810
harmalanPlasmodium falciparum 3D7Potency8.912510
8-(4-benzenesulfonylamino)quinolinePlasmodium falciparum 3D7Potency1.995310
deferrioxamine ePlasmodium falciparum 3D7Potency6.309610
tanshinone ii aPlasmodium falciparum 3D7Potency15.848910
2-[carboxymethyl-[2-(2,6-diethylanilino)-2-oxoethyl]amino]acetic acidPlasmodium falciparum 3D7Potency1.122010
1-benzylimidazole-4,5-dicarboxylic acidPlasmodium falciparum 3D7Potency37.685810
biotinPlasmodium falciparum 3D7Potency0.316210
desaminosulfamethazinePlasmodium falciparum 3D7Potency0.946610
cirsimaritinPlasmodium falciparum 3D7Potency35.481310
bis(1-methylbenzimidazol-2-yl)methanePlasmodium falciparum 3D7Potency28.183810
2-[4-(4-methoxyphenyl)-1-piperazinyl]pyrimidinePlasmodium falciparum 3D7Potency0.946610
fonsecinPlasmodium falciparum 3D7Potency8.912510
brazilinPlasmodium falciparum 3D7Potency12.589310
colchiceinePlasmodium falciparum 3D7Potency6.309610
1-benzothiophen-2-yl-(4-dimethylaminophenyl)methanolPlasmodium falciparum 3D7Potency39.810710
2-hydroxyestradiolPlasmodium falciparum 3D7Potency14.125410
6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrilePlasmodium falciparum 3D7Potency0.707910
4-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)methylamino]benzoic acidPlasmodium falciparum 3D7Potency28.183810
nsc 83265Plasmodium falciparum 3D7Potency15.848910
n,n'-bis(salicylidene)-1,6-hexanediaminePlasmodium falciparum 3D7Potency31.622810
n-methylserotonin oxalate saltPlasmodium falciparum 3D7Potency22.387210
4-benzyloxy-2-nitroanilinePlasmodium falciparum 3D7Potency39.810710
oxolamine citratePlasmodium falciparum 3D7Potency25.118910
4-amino-1,2-dithiolane-4-carboxylic acidPlasmodium falciparum 3D7Potency28.183810
nsc-126771Plasmodium falciparum 3D7Potency7.079510
2-glycineamide-5-chlorophenyl-2-pyrryl ketonePlasmodium falciparum 3D7Potency22.387210
(1-tert-butyl-5-phenyl-3-pyrrolyl)-phenylmethanonePlasmodium falciparum 3D7Potency28.183810
N-[4-[[(3,4-dimethylanilino)-oxomethyl]amino]phenyl]-N-methylacetamidePlasmodium falciparum 3D7Potency3.981110
1-(benzenesulfonyl)indolePlasmodium falciparum 3D7Potency39.810710
hematoxylinPlasmodium falciparum 3D7Potency31.622810
3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency7.079510
4,5,7-trihydroxy-9,10-dioxo-2-anthracenecarboxylic acidPlasmodium falciparum 3D7Potency8.912510
7-benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl esterPlasmodium falciparum 3D7Potency22.387210
nsc354961Plasmodium falciparum 3D7Potency39.810710
tosylphenylalanyl chloromethyl ketonePlasmodium falciparum 3D7Potency4.466810
(R)-norlaudanosolinePlasmodium falciparum 3D7Potency2.511910
bacampicillin hydrochloridePlasmodium falciparum 3D7Potency1.995310
N-(3-Benzooxazol-2-yl-4-hydroxy-phenyl)-2-p-tolyloxyacetamidePlasmodium falciparum 3D7Potency3.548110
dironylPlasmodium falciparum 3D7Potency4.466810
desthiobiotinPlasmodium falciparum 3D7Potency7.943310
6-bromoindirubin-3'-oximePlasmodium falciparum 3D7Potency10.000010
histidyl-proline diketopiperazinePlasmodium falciparum 3D7Potency15.848910
L-cycloserinePlasmodium falciparum 3D7Potency14.125410
afimoxifenePlasmodium falciparum 3D7Potency35.481310
trimethylcolchicinic acidPlasmodium falciparum 3D7Potency39.810710
azaserinePlasmodium falciparum 3D7Potency39.810710
(2S)-2-[[[4-[[[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxo-3-phenylpropan-2-yl]amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-3-phenylpropanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency4.466810
menadione sodium bisulfite, trihydratePlasmodium falciparum 3D7Potency28.183810
2-(1H-benzimidazol-2-ylthio)-1-thiophen-2-ylethanonePlasmodium falciparum 3D7Potency39.810710
N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamidePlasmodium falciparum 3D7Potency15.003010
N'-[(2-chlorophenyl)-oxomethyl]-5-(trifluoromethoxy)-1H-indole-2-carbohydrazidePlasmodium falciparum 3D7Potency1.778310
Methyl HaematommatePlasmodium falciparum 3D7Potency3.162310
1-[[(5-hex-1-ynyl-2-furanyl)-oxomethyl]amino]-3-phenylureaPlasmodium falciparum 3D7Potency2.818410
2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepinePlasmodium falciparum 3D7Potency15.848910
2-(1-piperazinyl)-4-amino-6,7-dimethoxyquinazolinePlasmodium falciparum 3D7Potency25.118910
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanonePlasmodium falciparum 3D7Potency12.589310
benzylidenephthalidePlasmodium falciparum 3D7Potency39.810710
2-[[5-[2-(1H-benzimidazol-2-yl)ethyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamidePlasmodium falciparum 3D7Potency22.387210
LSM-34798Plasmodium falciparum 3D7Potency15.003010
2-(4-chlorophenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamidePlasmodium falciparum 3D7Potency22.387210
N-(2-pyridinylmethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-9-aminePlasmodium falciparum 3D7Potency7.079510
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency23.778110
2,4-dichlorobenzoic acid 1,2,4-triazol-1-ylmethyl esterPlasmodium falciparum 3D7Potency2.818410
1-(3-chloro-4-methoxyphenyl)sulfonyl-N-(3-pyridinyl)-3-piperidinecarboxamidePlasmodium falciparum 3D7Potency22.387210
11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrilePlasmodium falciparum 3D7Potency44.668410
4-[2-[1-(4-methoxyphenyl)sulfonyl-2-benzimidazolyl]ethyl]morpholinePlasmodium falciparum 3D7Potency3.981110
2-[(1-tert-butyl-5-tetrazolyl)-thiophen-2-ylmethyl]-2-azaspiro[5.5]undecanePlasmodium falciparum 3D7Potency4.228410
N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-4-oxo-4-(1-piperidinyl)butanamidePlasmodium falciparum 3D7Potency3.358710
N-[2-[1,3-benzodioxol-5-yl-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]amino]-2-oxoethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency39.810710
N-[2-(tert-butylamino)-2-oxo-1-pyridin-4-ylethyl]-N-cyclopropyl-4-thiadiazolecarboxamidePlasmodium falciparum 3D7Potency28.183810
5-(1,3-benzodioxol-5-yl)-1-methyl-2-imidazolaminePlasmodium falciparum 3D7Potency2.667910
2-[[5-(4-fluorophenyl)-1-methyl-2-imidazolyl]thio]-N-[2-(4-morpholinyl)phenyl]acetamidePlasmodium falciparum 3D7Potency35.481310
3-[2-hydroxy-3-(4-morpholinyl)propyl]-5,5-dimethylimidazolidine-2,4-dionePlasmodium falciparum 3D7Potency11.220210
2-[[5-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]thio]acetic acid butyl esterPlasmodium falciparum 3D7Potency31.622810
1-(ethylamino)-3-[3-(ethylamino)-2-hydroxypropoxy]-2-propanolPlasmodium falciparum 3D7Potency25.118910
1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonylazepanePlasmodium falciparum 3D7Potency21.192310
2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-[2-(1-piperidinyl)phenyl]acetamidePlasmodium falciparum 3D7Potency8.436810
N-[1-[4-(4-methylphenyl)-2-thiazolyl]-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamidePlasmodium falciparum 3D7Potency3.548110
N-(1,3-benzodioxol-5-yl)-2-[4-(4-phenyl-2-thiazolyl)-1-piperazinyl]acetamidePlasmodium falciparum 3D7Potency26.679510
2-[(2-ethyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)thio]-N-(2-furanylmethyl)acetamidePlasmodium falciparum 3D7Potency7.079510
4-[3-(4-fluorophenyl)-2,5,6-trimethyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholinePlasmodium falciparum 3D7Potency10.000010
[4-[5-tert-butyl-3-[(2-chlorophenyl)methyl]-7-triazolo[4,5-d]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanonePlasmodium falciparum 3D7Potency39.810710
6-ethoxy-3-[[2-furanylmethyl-[[1-(phenylmethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-onePlasmodium falciparum 3D7Potency15.003010
1-cyclohexyl-5-(2-phenoxyethylthio)tetrazolePlasmodium falciparum 3D7Potency35.481310
N-(2,1,3-benzothiadiazol-4-yl)-3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamidePlasmodium falciparum 3D7Potency13.371410
3-[[1-[1-(2-furanylmethyl)-5-tetrazolyl]propyl-(2-phenylethyl)amino]methyl]-7-methoxy-1H-quinolin-2-onePlasmodium falciparum 3D7Potency12.589310
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamidePlasmodium falciparum 3D7Potency14.125410
1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanonePlasmodium falciparum 3D7Potency35.481310
2-[[5-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl esterPlasmodium falciparum 3D7Potency10.000010
1-[(3,4-dimethoxyphenyl)-[1-(thiophen-2-ylmethyl)-5-tetrazolyl]methyl]-4-phenylpiperazinePlasmodium falciparum 3D7Potency25.118910
N-[2-(1H-benzimidazol-2-yl)ethyl]-2-[4-(5-fluoro-1-benzotriazolyl)-1-piperidinyl]acetamidePlasmodium falciparum 3D7Potency2.667910
1-[(2-methoxyphenyl)-[1-(2-phenylethyl)-5-tetrazolyl]methyl]-4-phenylpiperazinePlasmodium falciparum 3D7Potency14.125410
2-[[5-[[2-(3-chloroanilino)-4-thiazolyl]methyl]-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]thio]acetic acid methyl esterPlasmodium falciparum 3D7Potency9.466210
opc-2009Plasmodium falciparum 3D7Potency7.943310
mitobronitolPlasmodium falciparum 3D7Potency31.622810
benidipine hydrochloridePlasmodium falciparum 3D7Potency31.622810
dithizonePlasmodium falciparum 3D7Potency19.952610
3-(4-butyl-3,5-dimethyl-1-pyrazolyl)-5-methyl-[1,2,4]triazino[5,6-b]indolePlasmodium falciparum 3D7Potency1.000010
8-(2-furanyl)-6-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-3,3-dimethyl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrilePlasmodium falciparum 3D7Potency15.003010
N-[(2R,4S)-2-methyl-1-(1-oxopropyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamidePlasmodium falciparum 3D7Potency3.162310
7-methyl-3-(4-morpholinyl)-1-(prop-2-enylamino)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrilePlasmodium falciparum 3D7Potency2.818410
2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanonePlasmodium falciparum 3D7Potency0.707910
3-(5-cycloheptylidene-4-oxo-2-sulfanylidene-3-thiazolidinyl)propanoic acidPlasmodium falciparum 3D7Potency39.810710
4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazolePlasmodium falciparum 3D7Potency37.685810
2-(2-oxo-3H-1,4-benzoxazin-4-yl)acetic acid [2-(3-bromo-4-methoxyphenyl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency44.668410
5-[(4-chlorophenyl)methylamino]-6-methyl-2H-1,2,4-triazin-3-onePlasmodium falciparum 3D7Potency6.309610
N-cyano-N'-propan-2-ylcarbamimidothioic acid [2-(2-methoxyanilino)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency29.934910
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-phenylacetamidePlasmodium falciparum 3D7Potency33.587510
1,3-dimethyl-6-(1-naphthalenyl)pyrrolo[3,4-d]pyrimidine-2,4-dionePlasmodium falciparum 3D7Potency5.011910
3-(3,5-dimethoxyphenyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency28.183810
2-(4-chlorophenyl)-5-(1-piperidinyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency13.371410
N-[5-[[2-(4-methylanilino)-2-oxoethyl]thio]-1,3,4-thiadiazol-2-yl]-2-(4-morpholinyl)acetamidePlasmodium falciparum 3D7Potency28.183810
1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrilePlasmodium falciparum 3D7Potency26.679510
2-amino-4-(2-ethoxyphenyl)-7-methyl-5-oxo-6-(2-pyridinylmethyl)-4H-pyrano[3,2-c]pyridine-3-carbonitrilePlasmodium falciparum 3D7Potency2.993510
N-(3-methoxyphenyl)-5-oxo-6,7-dihydro-[1,2,4]triazolo[3,4-b][1,3]thiazine-7-carboxamidePlasmodium falciparum 3D7Potency39.810710
1-[(4-methylphenyl)methyl]-4-[4-(4-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidinePlasmodium falciparum 3D7Potency1.412510
5-(4-methoxyphenyl)-7-(4-methylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidinePlasmodium falciparum 3D7Potency15.003010
4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency12.589310
5-bromo-N-(2-pyridinylmethyl)-2-thiophenesulfonamidePlasmodium falciparum 3D7Potency16.833610
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanonePlasmodium falciparum 3D7Potency31.622810
N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamidePlasmodium falciparum 3D7Potency44.668410
2-(3,5-dimethyl-1-pyrazolyl)-4-(4-morpholinyl)-5-pyrimidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency15.848910
7-hexyl-3-methyl-8-(4-phenyl-1-piperazinyl)purine-2,6-dionePlasmodium falciparum 3D7Potency39.810710
5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-(2-furanyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency13.371410
2-(4-methoxyphenyl)-3-propylimidazo[4,5-b]quinoxalinePlasmodium falciparum 3D7Potency9.466210
3-[[2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-1-oxoethyl]amino]-6-methyl-1H-indole-2-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency33.587510
5-(4-methyl-1-piperidinyl)-2-(1-naphthalenylmethyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency28.183810
LSM-19719Plasmodium falciparum 3D7Potency22.387210
5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-(1-naphthalenylmethyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency39.810710
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dionePlasmodium falciparum 3D7Potency15.848910
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanonePlasmodium falciparum 3D7Potency31.622810
9,10-dimethoxy-2-(2-pyridinylmethylamino)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-onePlasmodium falciparum 3D7Potency39.810710
N5,N5-dimethyl-2,1,3-benzoxadiazole-4,5-diaminePlasmodium falciparum 3D7Potency25.118910
2-[[(4-acetyloxy-3-methoxyphenyl)-oxomethyl]amino]-5-hydroxybenzoic acidPlasmodium falciparum 3D7Potency21.192310
N-(3,4-dihydro-1H-[1,4]thiazino[4,3-a]benzimidazol-8-yl)butanamidePlasmodium falciparum 3D7Potency39.810710
3-(2-furanylmethyl)-8-(4-methoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrilePlasmodium falciparum 3D7Potency0.631010
6-amino-1-(4-fluorophenyl)-3-methyl-4-thiophen-2-yl-5-pyrazolo[3,4-b]pyridinecarbonitrilePlasmodium falciparum 3D7Potency17.782810
2-methoxy-6-[[(1-propyl-5-benzimidazolyl)amino]methyl]phenolPlasmodium falciparum 3D7Potency0.631010
4,9-dimethyl-3-(2H-tetrazol-5-ylmethoxy)-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-6-onePlasmodium falciparum 3D7Potency3.548110
2-methoxy-1-(1-methyl-2-benzimidazolyl)-1-phenylethanaminePlasmodium falciparum 3D7Potency0.843710
mercaptopurinePlasmodium falciparum 3D7Potency14.125410
3,3',4,5'-tetrahydroxystilbenePlasmodium falciparum 3D7Potency7.079510
4-methoxy-N-(5-methyl-3-isoxazolyl)benzamidePlasmodium falciparum 3D7Potency5.623410
2-mercaptonicotinic acidPlasmodium falciparum 3D7Potency39.810710
L-histidine 2-naphthylamidePlasmodium falciparum 3D7Potency10.000010
5-(4-chlorophenyl)-4h-1,2,4-triazole-3-thiolPlasmodium falciparum 3D7Potency2.511910
4-(3-amino-2-imidazo[1,2-a]pyridinyl)-2-methoxyphenolPlasmodium falciparum 3D7Potency39.810710
isatin beta-thiosemicarbazonePlasmodium falciparum 3D7Potency12.589310
4-cyclohexyl-3-(3-pyridinyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency39.810710
4-cyclohexyl-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency22.387210
6-(2-methyl-3-benzofuranyl)-2,3-dihydroimidazo[2,1-b]thiazolePlasmodium falciparum 3D7Potency22.387210
1-(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)ethanonePlasmodium falciparum 3D7Potency37.685810
2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamidePlasmodium falciparum 3D7Potency19.952610
benzylidenephthalidePlasmodium falciparum 3D7Potency39.810710
5,6-diphenyl-1,2,4-triazine-3-thiolPlasmodium falciparum 3D7Potency1.412510
n-phenyl-n'-2-pyridylthioureaPlasmodium falciparum 3D7Potency35.481310
3,5,5-trimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-onePlasmodium falciparum 3D7Potency7.943310
N1-(6-bromo-4-quinazolinyl)-N4,N4-dimethylbenzene-1,4-diaminePlasmodium falciparum 3D7Potency14.125410
3,5-dimethoxy-N-(1H-1,2,4-triazol-5-yl)benzamidePlasmodium falciparum 3D7Potency3.981110
5-(4-chlorophenyl)-3H-thieno[2,3-d]pyrimidine-4-thionePlasmodium falciparum 3D7Potency11.220210
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamidePlasmodium falciparum 3D7Potency3.162310
ceefourin 1Plasmodium falciparum 3D7Potency22.387210
4-(3-chlorophenyl)thiosemicarbazidePlasmodium falciparum 3D7Potency28.183810
5-methyl-6-phenyl-3H-thieno[2,3-d]pyrimidine-4-thionePlasmodium falciparum 3D7Potency3.548110
5-(4-cyclohexylphenyl)-1,2-dihydropyrazol-3-onePlasmodium falciparum 3D7Potency22.387210
4-(4-chlorophenyl)-3-(2-quinolinyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency1.995310
4-(4-fluorophenyl)-3H-thiazole-2-thionePlasmodium falciparum 3D7Potency15.848910
5-(2,3-dihydro-1H-inden-5-yloxymethyl)-2-furancarbohydrazidePlasmodium falciparum 3D7Potency22.387210
N-(2-chlorophenyl)hydrazine-1-carbothioamidePlasmodium falciparum 3D7Potency25.118910
10-methyl-3-phenothiazinaminePlasmodium falciparum 3D7Potency5.623410
4-[[[2-(4-fluorophenyl)ethylamino]-sulfanylidenemethyl]amino]benzoic acid ethyl esterPlasmodium falciparum 3D7Potency17.782810
phenylthiazolylthioureaPlasmodium falciparum 3D7Potency2.511910
3-(1-azepanyl)-4-chloro-1-(2-methylphenyl)pyrrole-2,5-dionePlasmodium falciparum 3D7Potency26.679510
vu0038882Plasmodium falciparum 3D7Potency3.981110
5-cyano-2-methyl-6-sulfanylidene-1H-pyridine-3-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
6-amino-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dionePlasmodium falciparum 3D7Potency22.387210
1-cyclohexyl-3-[[oxo(thiophen-2-yl)methyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
N-[4-(diethylamino)phenyl]-N'-phenylureaPlasmodium falciparum 3D7Potency39.810710
2-[(4-oxo-2-phenyl-1-benzopyran-3-yl)oxy]acetic acidPlasmodium falciparum 3D7Potency0.002410
1-benzoyl-4-phenyl-3-thiosemicarbazidePlasmodium falciparum 3D7Potency0.316210
krm iiiPlasmodium falciparum 3D7Potency3.981110
1-(3-fluorophenyl)-3-(2-pyridinylmethyl)thioureaPlasmodium falciparum 3D7Potency28.183810
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency3.162310
2-(4-hydroxyanilino)-1,4-naphthoquinonePlasmodium falciparum 3D7Potency28.183810
4-[(2-methoxy-1-naphthalenyl)methyl]thiomorpholinePlasmodium falciparum 3D7Potency31.622810
2-[[3-[(2-hydroxyphenyl)methyl]-1,3-diazinan-1-yl]methyl]phenolPlasmodium falciparum 3D7Potency0.794310
3-pyridinecarboxylic acid (5-chloro-8-quinolinyl) esterPlasmodium falciparum 3D7Potency3.548110
N2,N4-ditert-butyl-6-hydrazinyl-1,3,5-triazine-2,4-diaminePlasmodium falciparum 3D7Potency2.511910
2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazolePlasmodium falciparum 3D7Potency26.679510
2-[(4-fluorophenyl)methylthio]-5-(2-methylphenyl)-1,3,4-oxadiazolePlasmodium falciparum 3D7Potency26.679510
2,2,2-trifluoro-N-(2-methyl-8-quinolinyl)acetamidePlasmodium falciparum 3D7Potency28.183810
3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid methyl esterPlasmodium falciparum 3D7Potency44.668410
N'-[(4-chlorophenyl)-oxomethyl]-2-pyrazinecarbohydrazidePlasmodium falciparum 3D7Potency2.238710
2-(5,7-dimethyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinyl)acetic acid ethyl esterPlasmodium falciparum 3D7Potency22.387210
2-hydroxy-2,2-bis(4-methylphenyl)-N'-(2-pyridinyl)acetohydrazidePlasmodium falciparum 3D7Potency3.162310
3-(2-phenoxyethyl)-1H-benzimidazole-2-thionePlasmodium falciparum 3D7Potency31.622810
2-[4-[(3-fluorophenyl)methyl]-1-piperazinyl]pyrimidinePlasmodium falciparum 3D7Potency29.934910
3-[(4-methylphenoxy)methyl]-4-phenyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency10.000010
4-(4-chlorophenyl)-3-[(4-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.079510
3-[2-(4-methyl-2-propan-2-ylphenoxy)ethyl]-1H-benzimidazole-2-thionePlasmodium falciparum 3D7Potency12.589310
4-(6-methyl-4-phenyl-2-quinazolinyl)-1-piperazinecarboxaldehydePlasmodium falciparum 3D7Potency26.679510
3-(4-ethoxyphenyl)-1H-pyrazole-5-carbohydrazidePlasmodium falciparum 3D7Potency17.782810
1-[4-(1-azepanyl)-3-fluorophenyl]-1-propanonePlasmodium falciparum 3D7Potency28.183810
LSM-28278Plasmodium falciparum 3D7Potency8.436810
4-chloro-N-(4-hydrazinyl-6-methyl-2-pyrimidinyl)benzenesulfonamidePlasmodium falciparum 3D7Potency35.481310
n-benzamidothioureaPlasmodium falciparum 3D7Potency0.843710
6-ethyl-5-methyl-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-onePlasmodium falciparum 3D7Potency0.707910
6-bromo-3-phenyl-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency17.782810
1-[[2-(3-methylanilino)-1-oxoethyl]amino]-3-phenylthioureaPlasmodium falciparum 3D7Potency0.707910
3-amino-4-(4-chlorophenyl)-6-cyclopropyl-2-thieno[2,3-b]pyridinecarbonitrilePlasmodium falciparum 3D7Potency15.848910
4-cyano-3-methyl-5-(4-methylphenyl)-2-thiophenecarbohydrazidePlasmodium falciparum 3D7Potency8.912510
N-[[(4,6-dimethyl-2-pyrimidinyl)amino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency3.548110
[4-(2-methylphenyl)-1-piperazinyl]-(4-nitrophenyl)methanethionePlasmodium falciparum 3D7Potency17.782810
3-(3-nitrophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.943310
4-prop-2-enyl-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency39.810710
8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thionePlasmodium falciparum 3D7Potency12.589310
LSM-20909Plasmodium falciparum 3D7Potency35.481310
2-[[4-amino-2-(ethylamino)-5-thiazolyl]-phenylmethylidene]propanedinitrilePlasmodium falciparum 3D7Potency3.981110
2-[4-(4-fluorophenyl)-2-thiazolyl]-5-methyl-4H-pyrazol-3-onePlasmodium falciparum 3D7Potency5.972810
N-[[(2,4-dimethyl-8-quinolinyl)amino]-sulfanylidenemethyl]-4-methylbenzamidePlasmodium falciparum 3D7Potency3.548110
2-[2-[[benzamido(sulfanylidene)methyl]amino]-4-thiazolyl]acetic acid ethyl esterPlasmodium falciparum 3D7Potency17.782810
5-bromo-N-[(2-pyridinylamino)-sulfanylidenemethyl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency11.220210
3-fluoro-N-(1H-1,2,4-triazol-5-yl)benzamidePlasmodium falciparum 3D7Potency15.848910
3-prop-2-enyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency3.548110
8-methyl-1,5-dihydropyrimido[5,4-b]indole-4-thionePlasmodium falciparum 3D7Potency1.778310
N-(cyclopentylideneamino)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamidePlasmodium falciparum 3D7Potency31.622810
N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-4-phenylbenzamidePlasmodium falciparum 3D7Potency14.125410
N-[(4-fluoroanilino)-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamidePlasmodium falciparum 3D7Potency25.118910
6-methyl-4-oxoquinolizine-1,3-dicarboxylic acid diethyl esterPlasmodium falciparum 3D7Potency10.000010
7-chloro 5-(2-chlorophenyl)-1,3-dihydro-2h-(1,4)-benzodiazepine-2-thionePlasmodium falciparum 3D7Potency31.622810
N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolaminePlasmodium falciparum 3D7Potency37.685810
3-propyl-1-(2-pyridinylmethylamino)-4-pyrido[1,2-a]benzimidazolecarbonitrilePlasmodium falciparum 3D7Potency3.162310
2-(4-ethylphenoxy)acetic acid (4-nitrophenyl) esterPlasmodium falciparum 3D7Potency3.548110
N-[(2,3-dimethoxyphenyl)methyl]-4-(4-methyl-1-piperidinyl)anilinePlasmodium falciparum 3D7Potency23.778110
2-phenyl-1H-quinazoline-4-thionePlasmodium falciparum 3D7Potency2.511910
3-(2-furanyl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency31.622810
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamidePlasmodium falciparum 3D7Potency3.162310
1-[[(1,3-dimethyl-4-pyrazolyl)-oxomethyl]amino]-3-(4-methylphenyl)thioureaPlasmodium falciparum 3D7Potency0.707910
1-[[(1,5-dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thioureaPlasmodium falciparum 3D7Potency31.622810
3-(4-ethyl-5-methyl-3-thiophenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.981110
3-(1,3-benzodioxol-5-yl)-4-(2,5-dimethylphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency5.972810
1-(3-methylphenyl)-3-[[oxo-(5-propyl-3-thiophenyl)methyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
3-(4,5-dimethyl-3-thiophenyl)-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency6.309610
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.358710
1-[[2-furanyl(oxo)methyl]amino]-3-(3-methylphenyl)thioureaPlasmodium falciparum 3D7Potency0.670210
4,5-dimethyl-2-[4-(3-nitrophenyl)-2-thiazolyl]-1H-pyrazol-3-onePlasmodium falciparum 3D7Potency25.118910
1-(4-methoxyphenyl)-3-[[oxo(thiophen-2-yl)methyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
N2,N4-bis(4-methoxyphenyl)pyrimidine-2,4-diaminePlasmodium falciparum 3D7Potency14.125410
2-(3-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazolePlasmodium falciparum 3D7Potency39.810710
6-amino-2-mercaptobenzothiazolePlasmodium falciparum 3D7Potency11.220210
3-(3,4-dimethylanilino)-1-thiophen-2-yl-1-propanonePlasmodium falciparum 3D7Potency22.387210
2-(4-methoxyphenoxy)-N-(2-methoxyphenyl)acetamidePlasmodium falciparum 3D7Potency2.377810
3-amino-6-cyclopropyl-4-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinecarbonitrilePlasmodium falciparum 3D7Potency11.220210
N-[[(6-methyl-4-pyrimidinyl)thio]methyl]benzamidePlasmodium falciparum 3D7Potency33.587510
N-[[(6-methoxy-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency8.912510
3-(4-bromoanilino)-1-(3-nitrophenyl)-1-propanonePlasmodium falciparum 3D7Potency22.387210
3-bromo-N-[(tert-butylamino)-sulfanylidenemethyl]-4-methoxybenzamidePlasmodium falciparum 3D7Potency19.952610
2-(1H-benzimidazol-2-ylmethyl)benzene-1,4-diolPlasmodium falciparum 3D7Potency28.183810
2-[[(3-bromophenyl)-oxomethyl]amino]-5-hydroxybenzoic acidPlasmodium falciparum 3D7Potency31.622810
3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamidePlasmodium falciparum 3D7Potency2.511910
3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazolePlasmodium falciparum 3D7Potency39.810710
2-(3,4-dimethylphenoxy)ethanethioic acid S-(4-methylphenyl) esterPlasmodium falciparum 3D7Potency17.782810
N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency8.912510
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)anilinePlasmodium falciparum 3D7Potency18.887610
5-(2-furanylmethylamino)-2-(2-methylphenyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency17.782810
N-[anilino(sulfanylidene)methyl]-5-bromo-2-furancarboxamidePlasmodium falciparum 3D7Potency39.810710
6-methoxy-4-methyl-2-[(2-methylphenyl)methylthio]quinazolinePlasmodium falciparum 3D7Potency22.387210
N-(3-ethylphenyl)-2-phenoxyacetamidePlasmodium falciparum 3D7Potency4.466810
2-(2-cyclohexylidenehydrazinyl)benzoic acidPlasmodium falciparum 3D7Potency22.387210
N-(4-ethoxyphenyl)-1,2,5-thiadiazole-3-carboxamidePlasmodium falciparum 3D7Potency39.810710
2-(2-methylphenoxy)-N-[2-(methylthio)phenyl]acetamidePlasmodium falciparum 3D7Potency25.118910
4-methoxy-6-phenyl-1H-pyrimidine-2-thionePlasmodium falciparum 3D7Potency2.511910
4-bromo-1-methyl-N-(2-thiazolyl)-3-pyrazolecarboxamidePlasmodium falciparum 3D7Potency25.118910
5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamidePlasmodium falciparum 3D7Potency28.183810
deltoinPlasmodium falciparum 3D7Potency39.810710
1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dionePlasmodium falciparum 3D7Potency8.912510
5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazolePlasmodium falciparum 3D7Potency28.183810
4-chloro-N-[[(4,6-dimethyl-2-pyrimidinyl)thio]methyl]benzamidePlasmodium falciparum 3D7Potency7.943310
7,8-dichloropyrido[1,2-a]benzimidazolePlasmodium falciparum 3D7Potency5.623410
N'-(1,3-benzoxazol-2-yl)benzohydrazidePlasmodium falciparum 3D7Potency31.622810
N'-(1,3-benzothiazol-2-yl)-4-fluorobenzohydrazidePlasmodium falciparum 3D7Potency2.818410
3-(4-ethoxyphenyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency14.125410
1-(cycloheptylideneamino)-3-(4-fluorophenyl)thioureaPlasmodium falciparum 3D7Potency7.519310
N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamidePlasmodium falciparum 3D7Potency35.481310
3-amino-4-methoxy-1H-indole-2-carbohydrazidePlasmodium falciparum 3D7Potency25.118910
N'-[1-oxo-2-(4-propan-2-ylphenoxy)ethyl]-2-pyrazinecarbohydrazidePlasmodium falciparum 3D7Potency1.778310
1-(4-methylphenyl)sulfonyl-4-phenyl-3-pyrazolaminePlasmodium falciparum 3D7Potency0.266810
2-mercaptonaphth(2,3)imidazolePlasmodium falciparum 3D7Potency15.848910
2-(2-fluorophenyl)-5-(4-methyl-1-piperidinyl)-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency15.848910
2-(4-ethoxyanilino)-3-methoxynaphthalene-1,4-dionePlasmodium falciparum 3D7Potency8.912510
3-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]triazin-4-onePlasmodium falciparum 3D7Potency26.679510
8-methyl-2-(3-methylbutyl)-1,2,4-triazaspiro[4.5]decane-3-thionePlasmodium falciparum 3D7Potency17.782810
3-[5-(2-furanyl)-1H-pyrazol-3-yl]-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.548110
4-(4-chlorophenyl)-3-(2-phenylethyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.943310
curcuminPlasmodium falciparum 3D7Potency7.079510
1-(4-methyl-2-oxo-1-benzopyran-7-yl)-3-(2-pyridinylmethyl)thioureaPlasmodium falciparum 3D7Potency19.952610
2-[[(4-methyl-1-pyrazolyl)-oxomethyl]amino]benzoic acid methyl esterPlasmodium falciparum 3D7Potency8.912510
1-(3-acetylphenyl)-3-(2-pyridinylmethyl)ureaPlasmodium falciparum 3D7Potency9.466210
4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency25.118910
1-(3,4-dichlorophenyl)-3-(3,5-dimethylphenyl)thioureaPlasmodium falciparum 3D7Potency25.118910
1-[[(2-chlorophenyl)-oxomethyl]amino]-3-(2-methoxy-5-methylphenyl)thioureaPlasmodium falciparum 3D7Potency0.335910
N-[(3-bromo-4,5-diethoxyphenyl)methyl]-4-(4-morpholinyl)anilinePlasmodium falciparum 3D7Potency14.125410
N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-2,3-dihydro-1,4-benzodioxin-6-aminePlasmodium falciparum 3D7Potency22.387210
N-[(1-ethyl-2-oxo-6-benzo[cd]indolyl)sulfonyl]-N-(4-methoxyphenyl)-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency10.000010
2-[(1,5-diphenyl-2-imidazolyl)thio]-N-(2-furanylmethyl)acetamidePlasmodium falciparum 3D7Potency10.621310
1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-(2,5-dimethylphenyl)thioureaPlasmodium falciparum 3D7Potency0.794310
1-[[[2-(difluoromethoxy)phenyl]-oxomethyl]amino]-3-(4-fluorophenyl)thioureaPlasmodium falciparum 3D7Potency0.067010
1-[[[2-(difluoromethoxy)phenyl]-oxomethyl]amino]-3-(3-methylphenyl)thioureaPlasmodium falciparum 3D7Potency0.631010
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency0.266810
N-(5-bromo-8-quinolinyl)-5-[(4-chloro-1-pyrazolyl)methyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency35.481310
1-[[[2-(2,4-dichlorophenyl)-4-quinolinyl]-oxomethyl]amino]-3-phenylureaPlasmodium falciparum 3D7Potency1.000010
5-(4-bromophenyl)-N-[[(2-propyl-5-tetrazolyl)amino]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency3.162310
3-bromo-5-ethoxy-N-(4-fluorophenyl)-4-methoxybenzamidePlasmodium falciparum 3D7Potency8.912510
1-[[2-(2,4-dichlorophenoxy)-1-oxoethyl]amino]-3-(4-fluorophenyl)thioureaPlasmodium falciparum 3D7Potency1.888810
1-[[2-(4-chlorophenyl)-1-oxoethyl]amino]-3-(1-naphthalenyl)ureaPlasmodium falciparum 3D7Potency2.238710
N-[4-[[[2-(2,5-dimethylphenoxy)-1-oxoethyl]hydrazo]-oxomethyl]phenyl]propanamidePlasmodium falciparum 3D7Potency39.810710
2-bromo-N-[2,3-dihydroindol-1-yl(sulfanylidene)methyl]benzamidePlasmodium falciparum 3D7Potency5.623410
N-[[methyl-(phenylmethyl)amino]-sulfanylidenemethyl]-4-phenylbenzamidePlasmodium falciparum 3D7Potency1.258910
N-[(3-acetylanilino)-sulfanylidenemethyl]-5-bromo-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency11.220210
5-ethyl-2-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]-3-thiophenecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency1.995310
4-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-3-quinolinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency19.952610
5-bromo-3-pyridinecarboxylic acid [3-(2-naphthalenyloxy)-4-oxo-1-benzopyran-7-yl] esterPlasmodium falciparum 3D7Potency35.481310
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamidePlasmodium falciparum 3D7Potency11.220210
2-[[benzamido(sulfanylidene)methyl]amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acidPlasmodium falciparum 3D7Potency5.623410
3-chloro-5-(2-furanyl)-N-propan-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamidePlasmodium falciparum 3D7Potency0.707910
pyridine-2-carboxylic acid thiazol-2-ylamidePlasmodium falciparum 3D7Potency1.412510
1-[(4-fluorophenyl)methyl]-4-(3,4,5-trimethoxyphenyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterPlasmodium falciparum 3D7Potency25.118910
1-[(4-methylphenyl)methyl]-4-(3,4,5-trimethoxyphenyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterPlasmodium falciparum 3D7Potency19.952610
1-cyclopropyl-4-[4-(trifluoromethyl)phenyl]-4H-pyridine-3,5-dicarboxylic acid dimethyl esterPlasmodium falciparum 3D7Potency3.548110
2-[[5-[(4-methoxyphenyl)methyl]-1,3,4-oxadiazol-2-yl]thio]-N-(4-methyl-2-thiazolyl)acetamidePlasmodium falciparum 3D7Potency11.917310
3-(4-chlorophenyl)-5-propyl-1H-pyrazolo[1,5-a]pyrimidin-7-onePlasmodium falciparum 3D7Potency15.848910
N-[2-(2-pyridinyl)-3H-benzimidazol-5-yl]cyclohexanecarboxamidePlasmodium falciparum 3D7Potency6.309610
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanonePlasmodium falciparum 3D7Potency7.079510
2-ethyl-N-[1-[2-(1-piperidinyl)ethyl]-2-benzimidazolyl]-3-pyrazolecarboxamidePlasmodium falciparum 3D7Potency12.589310
3-[2-(3-methylphenoxy)ethyl]-1,3-benzothiazol-2-onePlasmodium falciparum 3D7Potency31.622810
3-[2-(4-methylphenoxy)ethyl]-1,3-benzothiazol-2-onePlasmodium falciparum 3D7Potency31.622810
2,5-dichloro-4-ethoxy-N-(2-pyridinylmethyl)benzenesulfonamidePlasmodium falciparum 3D7Potency21.192310
5-(4-bromophenyl)-1-methyl-N-(3-pyridinylmethyl)-2-imidazolaminePlasmodium falciparum 3D7Potency39.810710
N'-methyl-N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-N'-(phenylmethyl)butanediamidePlasmodium falciparum 3D7Potency2.818410
3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamidePlasmodium falciparum 3D7Potency29.934910
2-(3,4-dimethoxyphenyl)-8-methoxy-4,4-dimethyl-5H-isothiazolo[5,4-c]quinoline-1-thionePlasmodium falciparum 3D7Potency1.258910
4-(4-bromophenyl)-3-[(4-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.548110
N-[4-[[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency11.220210
3-methyl-N'-(1-oxo-2-phenoxyethyl)-1-phenyl-5-thieno[2,3-c]pyrazolecarbohydrazidePlasmodium falciparum 3D7Potency7.519310
4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolonePlasmodium falciparum 3D7Potency10.621310
1-[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanonePlasmodium falciparum 3D7Potency3.981110
2-(4-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-quinazolinaminePlasmodium falciparum 3D7Potency25.118910
4-(4-anilinoanilino)-2-quinazolinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency28.183810
N-(2-phenylethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamidePlasmodium falciparum 3D7Potency44.668410
3-imino-2-benzo[f][1]benzopyrancarbothioamidePlasmodium falciparum 3D7Potency14.125410
4-bromo-N'-(3,4-dihydro-2H-pyrrol-5-yl)benzohydrazidePlasmodium falciparum 3D7Potency5.623410
2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-(4,5-diphenyl-2-oxazolyl)acetamidePlasmodium falciparum 3D7Potency11.220210
N'-[2-(4-bromo-2-methylphenoxy)-1-oxoethyl]-2-pyrazinecarbohydrazidePlasmodium falciparum 3D7Potency1.122010
1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)ureaPlasmodium falciparum 3D7Potency1.412510
3-methyl-N-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]benzamidePlasmodium falciparum 3D7Potency35.481310
2-[(3-cyano-6-methyl-2-pyridinyl)thio]-N-(2-thiazolyl)acetamidePlasmodium falciparum 3D7Potency7.943310
2-(1,3-dioxo-2-isoindolyl)-N-(4-methyl-1,3-benzothiazol-2-yl)acetamidePlasmodium falciparum 3D7Potency1.122010
3,5-dimethoxy-N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency11.917310
2-(phenylmethyl)-5-[4-(phenylmethyl)-1-piperidinyl]-4-oxazolecarbonitrilePlasmodium falciparum 3D7Potency7.943310
N-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency0.843710
2-[(4-chlorophenyl)thio]-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamidePlasmodium falciparum 3D7Potency28.183810
N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency37.685810
6-(2,3-dihydroindol-1-ylmethyl)-3-phenylthiazolo[2,3-c][1,2,4]triazolePlasmodium falciparum 3D7Potency4.228410
2-[2-chloro-4-(2,3-dihydroindol-1-ylsulfonyl)phenoxy]-N-(2-pyridinylmethyl)acetamidePlasmodium falciparum 3D7Potency13.371410
1-[1-methyl-2-(1-pyrrolidinylmethyl)-5-benzimidazolyl]-3-phenylureaPlasmodium falciparum 3D7Potency18.887610
N-[[3-chloro-2-(4-morpholinyl)anilino]-sulfanylidenemethyl]-4-methoxy-3-nitrobenzamidePlasmodium falciparum 3D7Potency7.519310
4-(5-amino-1,2,4-oxadiazol-3-yl)-1,2,5-oxadiazol-3-aminePlasmodium falciparum 3D7Potency39.810710
1-[[4-(dimethylamino)phenyl]methyl]-1-(2-furanylmethyl)-3-(4-methoxyphenyl)thioureaPlasmodium falciparum 3D7Potency2.511910
2-[[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-(2-pyridinyl)acetamidePlasmodium falciparum 3D7Potency1.258910
N-(4-methyl-2-thiazolyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]acetamidePlasmodium falciparum 3D7Potency2.818410
N-[[4-(diethylamino)phenyl]methyl]-1-[2-(1-piperidinyl)ethyl]-2-benzimidazolaminePlasmodium falciparum 3D7Potency22.387210
N-(6-ethoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamidePlasmodium falciparum 3D7Potency3.162310
N-[4-[4-(ethylsulfonylamino)-3-methoxyphenyl]-2-methoxyphenyl]ethanesulfonamidePlasmodium falciparum 3D7Potency0.707910
3-(2,3-dimethyl-1H-indol-5-yl)-4-(3-methoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.079510
2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamidePlasmodium falciparum 3D7Potency26.679510
5-bromo-N-[[(3-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency39.810710
3-methoxy-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency39.810710
LSM-32435Plasmodium falciparum 3D7Potency14.125410
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamidePlasmodium falciparum 3D7Potency3.548110
1-(1-azepanyl)-2-(2-bromo-4-propan-2-ylphenoxy)ethanonePlasmodium falciparum 3D7Potency3.162310
5-[2-methyl-1-(phenylmethyl)-6-(trifluoromethyl)-4-pyridinylidene]-2-sulfanylidene-1,3-diazinane-4,6-dionePlasmodium falciparum 3D7Potency3.548110
N-[4-[[[[(4-tert-butylphenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]-2-methoxyphenyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency7.079510
LSM-17286Plasmodium falciparum 3D7Potency3.981110
2-[(2-cyanophenyl)thio]-N-[4-[dimethylamino(oxo)methyl]phenyl]benzamidePlasmodium falciparum 3D7Potency7.079510
2-(4-chlorophenyl)-N-[4-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]phenyl]acetamidePlasmodium falciparum 3D7Potency22.387210
2-(4-bromophenoxy)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]acetamidePlasmodium falciparum 3D7Potency2.818410
N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency17.782810
7-[4-(4-acetamidophenyl)sulfonyl-1-piperazinyl]-1-ethyl-6-fluoro-4-oxo-3-quinolinecarboxylic acidPlasmodium falciparum 3D7Potency25.118910
N-[4-(4-morpholinyl)phenyl]-5-(2-nitrophenyl)-2-furancarboxamidePlasmodium falciparum 3D7Potency7.943310
N-[[3-(2-oxazolo[4,5-b]pyridinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency8.912510
1-[5-(5-chloro-2-methylphenyl)-2-furanyl]-N-[4-(4-morpholinyl)phenyl]methaniminePlasmodium falciparum 3D7Potency11.220210
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanonePlasmodium falciparum 3D7Potency39.810710
2-[[5-(3-chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanonePlasmodium falciparum 3D7Potency25.118910
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanonePlasmodium falciparum 3D7Potency17.782810
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanonePlasmodium falciparum 3D7Potency39.810710
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.079510
2-[5-(2-aminophenyl)-2-tetrazolyl]-1-[4-(4-methoxyphenyl)-1-piperazinyl]ethanonePlasmodium falciparum 3D7Potency17.782810
1-(4-fluorophenyl)-2-[(2-propyl-4-quinazolinyl)thio]ethanonePlasmodium falciparum 3D7Potency39.810710
N'-[2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]-2-furancarbohydrazidePlasmodium falciparum 3D7Potency3.981110
N-[6-[[cyclohexyl(oxo)methyl]amino]-3-pyridinyl]-2-pyridinecarboxamidePlasmodium falciparum 3D7Potency17.782810
N'-[2-[[4-ethyl-5-(2-furanyl)-1,2,4-triazol-3-yl]thio]-1-oxoethyl]-4-methoxybenzohydrazidePlasmodium falciparum 3D7Potency7.079510
4-[(2,6-dichlorophenyl)thio]-5-methoxy-2-(2-pyridinyl)pyrimidinePlasmodium falciparum 3D7Potency1.888810
N',2-dimethyl-N'-[3-(trifluoromethyl)-2-quinoxalinyl]benzohydrazidePlasmodium falciparum 3D7Potency0.631010
2-[benzenesulfonyl(2-pyridinyl)amino]acetic acidPlasmodium falciparum 3D7Potency7.943310
1-[4-(2-fluorophenyl)-2-thiazolyl]-5-(trifluoromethyl)-4-pyrazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency23.778110
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidinePlasmodium falciparum 3D7Potency1.258910
4-[(3-methylphenyl)thio]-2-phenyl-5-pyrimidinecarboxylic acidPlasmodium falciparum 3D7Potency0.707910
4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency19.952610
N-[(4-methylphenyl)methyl]-2-(2-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamidePlasmodium falciparum 3D7Potency12.589310
1-methyl-5-[(4-methylphenyl)thio]-3-phenyl-4-pyrazolecarbonitrilePlasmodium falciparum 3D7Potency29.934910
6-methyl-5-phenyl-2-(phenylthio)-3-pyridinecarbonitrilePlasmodium falciparum 3D7Potency26.679510
5-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-2-phenylthiazolePlasmodium falciparum 3D7Potency39.810710
hydrazinopyrimidine-5-carbonitrilePlasmodium falciparum 3D7Potency3.548110
3-[2-(4-chlorophenyl)-4-thiazolyl]-4-ethyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency10.000010
3-phenyl-5-[(phenylthio)methyl]isoxazolePlasmodium falciparum 3D7Potency19.952610
3-(4-chlorophenyl)-5-[(phenylthio)methyl]isoxazolePlasmodium falciparum 3D7Potency22.387210
1-[[2-(1,2-benzoxazol-3-yl)-1-oxoethyl]amino]-3-(4-chlorophenyl)thioureaPlasmodium falciparum 3D7Potency0.707910
[[[3-[(4-methylphenyl)methoxy]-2-thiophenyl]-oxomethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.631010
5-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-1,2-dihydro-1,2,4-triazole-3-thionePlasmodium falciparum 3D7Potency2.818410
4-(2-quinoxalinylamino)benzoic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
4-[4-(2,4-dichlorophenyl)-2-thiazolyl]benzoic acidPlasmodium falciparum 3D7Potency1.995310
1-[[[1-(6-methyl-2-pyridinyl)-4-imidazolyl]-oxomethyl]amino]-3-phenylthioureaPlasmodium falciparum 3D7Potency0.707910
2-(5-methyl-3-oxo-1H-pyrazol-2-yl)-6-oxo-1H-pyrimidine-5-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency1.584910
5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency14.125410
5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency25.118910
6-methyl-5-[2-(2-methylphenoxy)ethyl]-2-sulfanylidene-1H-pyrimidin-4-onePlasmodium falciparum 3D7Potency14.125410
3,4-dichloro-N-(2-thiophen-2-ylethyl)benzamidePlasmodium falciparum 3D7Potency44.668410
4-[7-(4-methylphenyl)-5-phenyl-4-pyrrolo[2,3-d]pyrimidinyl]morpholinePlasmodium falciparum 3D7Potency15.848910
1-isonicotinoyl-4-(2-tolyl)thiosemicarbazidePlasmodium falciparum 3D7Potency0.631010
11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrilePlasmodium falciparum 3D7Potency31.622810
1-[[2-[[4-(4-chlorophenyl)-5-phenyl-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-3-phenylthioureaPlasmodium falciparum 3D7Potency35.481310
2-amino-6-ethyl-3-(3-isoxazolyl)-7-methoxy-1-benzopyran-4-onePlasmodium falciparum 3D7Potency4.228410
3-(4-phenylphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepinePlasmodium falciparum 3D7Potency31.622810
1,4-benzoquinone guanylhydrazone thiosemicarbazonePlasmodium falciparum 3D7Potency25.118910
auraptenPlasmodium falciparum 3D7Potency15.848910
1-[[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]amino]-3-phenylthioureaPlasmodium falciparum 3D7Potency0.707910
2-[2-[[1-oxo-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]ethyl]amino]-4-thiazolyl]acetic acid ethyl esterPlasmodium falciparum 3D7Potency0.100010
N-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]anilino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency14.125410
N-[(2-adamantylamino)-sulfanylidenemethyl]hexanamidePlasmodium falciparum 3D7Potency5.011910
1-amino-3-[3-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thioureaPlasmodium falciparum 3D7Potency22.387210
4-cyano-5-[[2-[[5-(2,4-dichlorophenyl)-1H-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-3-methyl-2-thiophenecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency28.183810
2-chloro-N-heptyl-N-(3-methylphenyl)acetamidePlasmodium falciparum 3D7Potency14.125410
1-[[3-(9-carbazolyl)-1-oxopropyl]amino]-3-(2-methylprop-2-enyl)thioureaPlasmodium falciparum 3D7Potency0.631010
4-methoxy-N-[[(1-oxo-2-phenoxyethyl)hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency5.011910
2-chloro-3-(prop-2-enylamino)naphthalene-1,4-dionePlasmodium falciparum 3D7Potency17.782810
N-[(benzenesulfonylhydrazo)-sulfanylidenemethyl]-4-methylbenzamidePlasmodium falciparum 3D7Potency6.309610
N-[[[2-(2-methoxyphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency3.548110
4-butyl-3-(5-ethyl-3-thiophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency14.125410
4-butyl-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency2.818410
1-ethyl-3-[[[2-(2-methylpropyl)-4-quinolinyl]-oxomethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.133710
4-butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.943310
1-(3-methoxyphenyl)-3-[[3-(4-nitro-1-pyrazolyl)-1-oxopropyl]amino]thioureaPlasmodium falciparum 3D7Potency7.943310
5-bromo-N-[[[oxo(thiophen-2-yl)methyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency2.993510
N-[[[(2-methylphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency2.818410
2-methyl-N-[[[oxo-(3,4,5-trimethoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency0.707910
4-chloro-N-[[[oxo-(3,4,5-trimethoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency0.794310
2-[[[(3-methyl-1-oxobutyl)amino]-sulfanylidenemethyl]amino]-N-phenylbenzamidePlasmodium falciparum 3D7Potency23.778110
chlorogenic acidPlasmodium falciparum 3D7Potency39.810710
2-chloro-4,6-diphenylpyrimidinePlasmodium falciparum 3D7Potency14.125410
1-[2-(2-methylphenoxy)ethyl]-3-phenylthioureaPlasmodium falciparum 3D7Potency0.707910
1-(3-phenoxypropyl)-3-indolecarbonitrilePlasmodium falciparum 3D7Potency35.481310
4-[4-(3-chlorophenyl)-1-piperazinyl]anilinePlasmodium falciparum 3D7Potency10.000010
1-ethyl-3-[[[(phenylmethyl)amino]-sulfanylidenemethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.631010
4-(2-bromo-4-methylphenyl)-3-[5-(2-furanyl)-1H-pyrazol-3-yl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency19.952610
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency22.387210
5-tert-butyl-3-(4-chlorophenyl)-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinaminePlasmodium falciparum 3D7Potency1.258910
3-(1,3-benzodioxol-5-yl)-4-(3-chloro-4-fluorophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency8.912510
2-[[2-[(2-fluorophenyl)methoxy]-3-methoxyphenyl]methylamino]phenolPlasmodium falciparum 3D7Potency39.810710
1-[[oxo(3-pyridinyl)methyl]amino]-3-(4-propan-2-ylphenyl)thioureaPlasmodium falciparum 3D7Potency0.707910
5-bromo-3-[[3-(3,3-dimethyl-1-piperidinyl)-1-oxopropyl]amino]-1H-indole-2-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency10.000010
N-[[(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamidePlasmodium falciparum 3D7Potency22.387210
1-[2-[(3-chloro-4-methoxyphenyl)methylthio]ethyl]-3-phenylthioureaPlasmodium falciparum 3D7Potency35.481310
N'-(4-phenyl-2-thiazolyl)-N-(2-pyridinylmethyl)oxamidePlasmodium falciparum 3D7Potency31.622810
N-(9-ethyl-3-carbazolyl)-2-[[4-ethyl-5-(2-furanyl)-1,2,4-triazol-3-yl]thio]acetamidePlasmodium falciparum 3D7Potency26.679510
N-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamidePlasmodium falciparum 3D7Potency31.622810
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency6.309610
1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thioureaPlasmodium falciparum 3D7Potency22.387210
2-(2-furanyl)-3,5-dimethyl-4-oxido-6-phenylpyrazin-1-ium 1-oxidePlasmodium falciparum 3D7Potency10.621310
1-[[(2-chlorophenyl)-oxomethyl]amino]-3-[3-(trifluoromethyl)phenyl]thioureaPlasmodium falciparum 3D7Potency0.631010
N-[[[(4-methoxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency35.481310
N-(4-fluorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamidePlasmodium falciparum 3D7Potency35.481310
4-oxo-3-[(1-oxo-2,2-diphenylethyl)amino]-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency0.843710
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency22.387210
3-amino-N-(2-fluorophenyl)-6-(2-furanyl)-2-thieno[2,3-b]pyridinecarboxamidePlasmodium falciparum 3D7Potency42.284110
N-(4,5-diphenyl-2-oxazolyl)-3-methoxybenzamidePlasmodium falciparum 3D7Potency1.412510
2-[5-(4-chlorophenyl)-1,3,5-dithiazinan-2-ylidene]-2-diethoxyphosphorylacetonitrilePlasmodium falciparum 3D7Potency35.481310
1-(3,5-dimethoxyphenyl)-3-(3-pyridinyl)thioureaPlasmodium falciparum 3D7Potency39.810710
2,2-diphenylacetic acid (2,6-dimethylphenyl) esterPlasmodium falciparum 3D7Potency25.118910
2-[[2-[(1-cyclohexyl-5-tetrazolyl)thio]-1-oxoethyl]amino]benzoic acid methyl esterPlasmodium falciparum 3D7Potency1.122010
(4,7-dichloro-1,3-benzothiazol-2-yl)hydrazinePlasmodium falciparum 3D7Potency28.183810
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(4-methyl-1-piperidinyl)sulfonyl]benzamidePlasmodium falciparum 3D7Potency2.511910
4-(4-chlorophenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterPlasmodium falciparum 3D7Potency14.125410
4-[4-(3-methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]morpholinePlasmodium falciparum 3D7Potency33.587510
3-(4-bromophenyl)-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency2.511910
4-(4-morpholinylsulfonyl)-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamidePlasmodium falciparum 3D7Potency1.778310
4-propan-2-ylbenzenecarbothioamidePlasmodium falciparum 3D7Potency39.810710
benzoic acid [2-oxo-2-[2-(phenylthio)anilino]ethyl] esterPlasmodium falciparum 3D7Potency1.778310
2-(2-bromophenyl)-5-[(7-nitro-4-quinazolinyl)oxymethyl]-1,3,4-oxadiazolePlasmodium falciparum 3D7Potency28.183810
2-(1,4-dioxo-3H-phthalazin-2-yl)-N-(5-methyl-4-phenyl-2-thiazolyl)acetamidePlasmodium falciparum 3D7Potency31.622810
N-(1,3-benzothiazol-2-yl)-3-(2,3-dihydroindol-1-ylsulfonyl)benzamidePlasmodium falciparum 3D7Potency25.118910
N-(4,5-dihydrothiazol-2-yl)-2-thiophen-2-yl-4-quinolinecarboxamidePlasmodium falciparum 3D7Potency28.183810
3-methyl-2-benzo[g]benzofurancarboxylic acid [2-[N-(2-cyanoethyl)anilino]-2-oxoethyl] esterPlasmodium falciparum 3D7Potency0.316210
6-(4-bromophenyl)-3-methyl-1-[2-(2H-tetrazol-5-yl)ethyl]-4-(trifluoromethyl)pyrazolo[3,4-b]pyridinePlasmodium falciparum 3D7Potency15.848910
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanonePlasmodium falciparum 3D7Potency18.887610
4-(4-hydroxyphenyl)-N-(phenylmethyl)-1-piperazinecarbothioamidePlasmodium falciparum 3D7Potency8.912510
3-amino-5-[3-(methylamino)propyl]-1H-pyrazole-4-carbonitrilePlasmodium falciparum 3D7Potency8.912510
1-[4-[(2-hydroxy-5-methylphenyl)-oxomethyl]-1-pyrazolyl]-2-(2-methyl-4-thiazolyl)ethanonePlasmodium falciparum 3D7Potency39.810710
3-(phenylmethyl)-2-sulfanylidene-1H-thieno[3,2-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency4.466810
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-phenyl-1,3,4-oxadiazol-2-aminePlasmodium falciparum 3D7Potency25.118910
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-(2-furanyl)-1,3,4-oxadiazol-2-aminePlasmodium falciparum 3D7Potency39.810710
2-(2-cyanophenoxy)acetic acid [2-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency15.848910
N-(5-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridin-2-yl)-2-(2-naphthalenyloxy)acetamidePlasmodium falciparum 3D7Potency39.810710
4-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)butanamidePlasmodium falciparum 3D7Potency28.183810
N-(1H-benzimidazol-2-yl)-3-[methyl-(4-methylphenyl)sulfamoyl]benzamidePlasmodium falciparum 3D7Potency3.548110
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3,5-dimethoxybenzamidePlasmodium falciparum 3D7Potency2.818410
5-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency3.981110
5-(3,4-dimethoxyphenyl)-3-(4-ethoxyphenyl)-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency2.818410
N-[[[oxo(thiophen-2-yl)methyl]hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency5.011910
3-phenyl-2-sulfanylidene-1H-benzofuro[3,2-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency22.387210
N-(5-ethyl-1,3,4-oxadiazol-2-yl)-4-[methyl(phenyl)sulfamoyl]benzamidePlasmodium falciparum 3D7Potency3.162310
4-(dipropylsulfamoyl)-N-[5-[(methylthio)methyl]-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency2.238710
4-[butyl(methyl)sulfamoyl]-N-[5-[(methylthio)methyl]-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency10.000010
4-[ethyl-(phenylmethyl)sulfamoyl]-N-(5-methyl-1,3,4-oxadiazol-2-yl)benzamidePlasmodium falciparum 3D7Potency3.162310
2-oxo-N-[2-[(2-phenyl-1H-indol-3-yl)thio]ethyl]-1-benzopyran-3-carboxamidePlasmodium falciparum 3D7Potency0.631010
3-[[(2,3-dimethylanilino)-sulfanylidenemethyl]amino]-1H-indole-2-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency14.125410
4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency1.412510
4-[bis(2-methylpropyl)sulfamoyl]-N-[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency35.481310
N-[(2S)-1-(1H-benzimidazol-2-ylamino)-3-methyl-1-oxobutan-2-yl]-3-methylbenzamidePlasmodium falciparum 3D7Potency14.125410
1-ethyl-3-[(1-oxo-2,2-diphenylethyl)amino]thioureaPlasmodium falciparum 3D7Potency0.299310
n-(5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamidePlasmodium falciparum 3D7Potency39.810710
2-[2-(1-naphthalenyloxy)ethylthio]pyrimidinePlasmodium falciparum 3D7Potency39.810710
5-bromo-N-[[(4-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency3.162310
1-(2,3-dimethyl-6-quinoxalinyl)-3-(3-hydroxypropyl)thioureaPlasmodium falciparum 3D7Potency39.810710
1-(4-butylphenyl)-3-(4-morpholinyl)thioureaPlasmodium falciparum 3D7Potency25.118910
N-(1,3-benzothiazol-2-yl)-2-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]thio]acetamidePlasmodium falciparum 3D7Potency10.000010
1-[3-(4-phenylphenoxy)propyl]-1,2,4-triazolePlasmodium falciparum 3D7Potency25.118910
1-(4-bromo-2-chlorophenyl)-3-[[oxo(pyridin-4-yl)methyl]amino]thioureaPlasmodium falciparum 3D7Potency1.258910
1-(3,4-dimethoxyphenyl)-3-[[2-(4-ethoxyphenyl)-1-oxoethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
4-[[[(2-methoxy-1-oxoethyl)hydrazo]-sulfanylidenemethyl]amino]benzoic acid ethyl esterPlasmodium falciparum 3D7Potency1.412510
N-[[(cyclohexylamino)-sulfanylidenemethyl]amino]carbamic acid tert-butyl esterPlasmodium falciparum 3D7Potency3.162310
4-butyl-3-(phenylmethyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency39.810710
1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-[(4-chlorophenyl)methyl]thioureaPlasmodium falciparum 3D7Potency0.707910
4-[[(2,4-difluoroanilino)-sulfanylidenemethyl]hydrazo]-N-(3,4-dimethylphenyl)-4-oxobutanamidePlasmodium falciparum 3D7Potency0.316210
N-[2-(1-naphthalenyl)-1,3-benzoxazol-5-yl]-1H-1,2,4-triazole-5-carboxamidePlasmodium falciparum 3D7Potency39.810710
1-(4-bromo-2-chlorophenyl)-3-(3-methyl-2-pyridinyl)thioureaPlasmodium falciparum 3D7Potency8.912510
N-[[[2-(2-bromo-4-propan-2-ylphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency1.584910
N-[4-[(3-bromo-5-methoxy-4-prop-2-enoxyphenyl)methylamino]-2-methoxyphenyl]-2-methylpropanamidePlasmodium falciparum 3D7Potency37.685810
6-bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(2-pyridinyl)-4-quinolinecarboxamidePlasmodium falciparum 3D7Potency17.782810
N-[[[[4-[(2-methyl-1-oxopropyl)amino]phenyl]-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency28.183810
2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamidePlasmodium falciparum 3D7Potency16.833610
N-[(3-bromoanilino)-sulfanylidenemethyl]-3-phenylpropanamidePlasmodium falciparum 3D7Potency1.995310
N-[[3-chloro-2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]butanamidePlasmodium falciparum 3D7Potency39.810710
N-[[(5-hydroxy-1-naphthalenyl)amino]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency35.481310
N-[[[(2,4-dichlorophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2,2-dimethylpropanamidePlasmodium falciparum 3D7Potency1.412510
4-phenyl-3-[2-(phenylmethylthio)ethyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency12.589310
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(5,7-diphenyl-2-pyrazolo[1,5-a]pyrimidinyl)methanonePlasmodium falciparum 3D7Potency1.122010
5-[2-(2-methoxyphenoxy)ethylthio]-1-(4-methylphenyl)tetrazolePlasmodium falciparum 3D7Potency12.589310
3,4-dimethyl-N-[sulfanylidene-[2-(trifluoromethyl)anilino]methyl]benzamidePlasmodium falciparum 3D7Potency25.118910
1-[2-(2-chlorophenoxy)ethoxy]-2-methoxy-4-methylbenzenePlasmodium falciparum 3D7Potency35.481310
1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzenePlasmodium falciparum 3D7Potency39.810710
2-chloro-N-[(2-pyrimidinylamino)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency11.220210
2-[2-(3-ethylphenoxy)ethyl]propanedioic acid diethyl esterPlasmodium falciparum 3D7Potency25.118910
N-[[(1-oxo-3-phenylpropyl)hydrazo]-sulfanylidenemethyl]pentanamidePlasmodium falciparum 3D7Potency35.481310
N-[3-cyano-4,5-bis(4-methoxyphenyl)-2-furanyl]acetamidePlasmodium falciparum 3D7Potency12.589310
1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thioureaPlasmodium falciparum 3D7Potency10.000010
N1-phenethylhydrazine-1-carbothioamidePlasmodium falciparum 3D7Potency1.000010
N-(1H-benzimidazol-2-yl)-4-(dimethylsulfamoyl)benzamidePlasmodium falciparum 3D7Potency3.162310
3-[[(4-tert-butylphenyl)-oxomethyl]amino]-1H-1,2,4-triazole-5-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency8.912510
N'-(3,4-dihydro-2H-pyrrol-5-yl)-2-(2-naphthalenylamino)acetohydrazidePlasmodium falciparum 3D7Potency10.000010
3-(4-methoxyphenyl)-N-[[[oxo(pyridin-4-yl)methyl]hydrazo]-sulfanylidenemethyl]-1-phenyl-4-pyrazolecarboxamidePlasmodium falciparum 3D7Potency0.707910
N-[5-(1,3-benzodioxol-5-ylmethyl)-4-methyl-2-thiazolyl]-4-chlorobenzamidePlasmodium falciparum 3D7Potency31.622810
1-[4-(difluoromethylthio)phenyl]-3-(phenylmethyl)thioureaPlasmodium falciparum 3D7Potency39.810710
3-methyl-5-[[1-oxo-2-(2-pyridinylmethylamino)ethyl]amino]thiophene-2,4-dicarboxylic acid diethyl esterPlasmodium falciparum 3D7Potency0.707910
2-[4-(4-chlorophenyl)-2-thiazolyl]ethanethioamidePlasmodium falciparum 3D7Potency17.782810
cyclohexanecarboxylic acid [2-oxo-2-[4-(1-piperidinyl)anilino]ethyl] esterPlasmodium falciparum 3D7Potency28.183810
2-(1,3-benzoxazol-2-ylthio)-N-(6-bromo-1,3-benzothiazol-2-yl)acetamidePlasmodium falciparum 3D7Potency39.810710
3-(1-azepanylsulfonyl)-4-chloro-N-(1H-1,2,4-triazol-5-yl)benzamidePlasmodium falciparum 3D7Potency1.683410
4-hexyl-3-thiophen-2-yl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.162310
2-(5H-[1,2,4]triazolo[5,1-a]isoindol-2-yl)ethanethioamidePlasmodium falciparum 3D7Potency37.685810
2,5-dimethyl-3-furancarboxylic acid [2-(2,3-dihydroindol-1-yl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency39.810710
4-methyl-N-[sulfanylidene-(1,2,4-triazol-4-ylamino)methyl]benzamidePlasmodium falciparum 3D7Potency19.952610
N-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)-2-furancarboxamidePlasmodium falciparum 3D7Potency39.810710
1-[[2-(1H-benzimidazol-2-ylthio)-1-oxoethyl]amino]-3-ethylthioureaPlasmodium falciparum 3D7Potency3.548110
3-[2-(cyclohexylamino)-4-(4-methoxyphenyl)-5-thiazolyl]propanoic acid methyl esterPlasmodium falciparum 3D7Potency6.309610
2-pyridin-4-yl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamidePlasmodium falciparum 3D7Potency31.622810
2-(1H-benzimidazol-2-yl)-1-(3-nitrophenyl)ethanonePlasmodium falciparum 3D7Potency25.118910
2-(4-chlorophenyl)-N-[4-(difluoromethylthio)phenyl]acetamidePlasmodium falciparum 3D7Potency39.810710
N-[4-(1-piperidinyl)phenyl]-2-quinolinecarboxamidePlasmodium falciparum 3D7Potency3.981110
2-[[5-(1,3-benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]thio]-N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]acetamidePlasmodium falciparum 3D7Potency0.707910
N-[4-bromo-3-(trifluoromethyl)phenyl]-2,4,6-trimethylbenzamidePlasmodium falciparum 3D7Potency0.316210
2,5-dimethyl-1-(3-methylphenyl)-N-(4-methylphenyl)-3-pyrrolecarboxamidePlasmodium falciparum 3D7Potency35.481310
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(2-methoxyphenyl)ethanonePlasmodium falciparum 3D7Potency12.589310
N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(4-morpholinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency39.810710
2-[(3-acetyl-5-oxo-4H-imidazol-2-yl)thio]-N-(4-methyl-5-phenyl-2-thiazolyl)-N-prop-2-enylacetamidePlasmodium falciparum 3D7Potency10.000010
1-(2,6-diethylphenyl)-3-[2-(3,4-dihydroxyphenyl)ethyl]thioureaPlasmodium falciparum 3D7Potency31.622810
4-chloro-3-(1-pyrrolidinylsulfonyl)benzoic acid [2-(butylamino)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency6.309610
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(3-nitroanilino)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency10.000010
N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-quinolinecarboxamidePlasmodium falciparum 3D7Potency3.548110
1-(2-chlorophenyl)-3-(3-phenylpropyl)thioureaPlasmodium falciparum 3D7Potency3.162310
6-[[(2-chlorophenyl)methyl-methylamino]methyl]-N2-(2-methylphenyl)-1,3,5-triazine-2,4-diaminePlasmodium falciparum 3D7Potency11.220210
N-[[(4-oxo-1-phenyl-5-pyrazolo[3,4-d]pyrimidinyl)amino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency14.125410
N2-[5-(3-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diaminePlasmodium falciparum 3D7Potency8.912510
2-phenyl-5-sulfanylidene-3,7,8,9,10,11-hexahydropyrazolo[4,5]pyrimido[3,5-a]azepin-1-onePlasmodium falciparum 3D7Potency37.685810
5-(3,4-dimethoxyphenyl)-2-methyl-4-(4-methyl-1-piperidinyl)thieno[2,3-d]pyrimidinePlasmodium falciparum 3D7Potency14.125410
N-[4-(4-methoxyphenyl)-2-thiazolyl]-5-methyl-2-phenyl-4-oxazolecarboxamidePlasmodium falciparum 3D7Potency0.707910
N-[2-(2,3-dimethylanilino)-2-oxoethyl]-3-(3-methylphenoxy)propanamidePlasmodium falciparum 3D7Potency3.162310
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(1H-pyrrol-2-yl)ethanonePlasmodium falciparum 3D7Potency10.000010
N-(1H-benzimidazol-2-yl)-4-(3-methylphenoxy)butanamidePlasmodium falciparum 3D7Potency8.912510
N-[[2-cyanoethyl(methyl)amino]-sulfanylidenemethyl]-4-(4-morpholinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency14.125410
5-methyl-2-(2-phenylethylamino)-4-thiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency31.622810
4-ethyl-3-[2-(4-methylphenyl)-4-quinolinyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency11.220210
2-[[3-[(4-fluorophenyl)methyl]-4-oxo-2-quinazolinyl]thio]-N-(thiophen-2-ylmethyl)acetamidePlasmodium falciparum 3D7Potency35.481310
5-(2-chlorophenyl)-2-(2-pyridinylmethyl)-3H-thieno[2,3-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency5.011910
4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-ethyl-1-benzopyran-2-onePlasmodium falciparum 3D7Potency5.011910
2-[[(6-chloro-4-oxo-3-prop-2-enyl-2-quinazolinyl)thio]methyl]isoindole-1,3-dionePlasmodium falciparum 3D7Potency28.183810
1-(2-benzofuranyl)-2-[(4-methyl-2-quinolinyl)thio]ethanonePlasmodium falciparum 3D7Potency17.782810
2-(2,4-dichlorophenoxy)-N-[2-(methylthio)phenyl]acetamidePlasmodium falciparum 3D7Potency15.848910
[4-(4-bromo-2-chlorophenyl)sulfonyl-1-piperazinyl]-(2-sulfanylidene-1H-pyridin-3-yl)methanonePlasmodium falciparum 3D7Potency3.548110
3-(2-furanylmethyl)-4-oxo-N,N-dipropyl-2-sulfanylidene-1H-quinazoline-7-carboxamidePlasmodium falciparum 3D7Potency15.848910
2-[4-(2-hydroxyphenyl)-1-piperazinyl]-N-(5-methyl-3-isoxazolyl)acetamidePlasmodium falciparum 3D7Potency18.887610
N-[4-(2-pyridinyl)-2-thiazolyl]cyclopentanecarboxamidePlasmodium falciparum 3D7Potency0.707910
N'-(4-quinazolinyl)acetohydrazidePlasmodium falciparum 3D7Potency19.952610
4-methyl-N'-(4-quinazolinyl)benzohydrazidePlasmodium falciparum 3D7Potency2.238710
2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methyl-methylamino]-N-(2-ethylphenyl)acetamidePlasmodium falciparum 3D7Potency0.670210
4-[[6-[(2-methyl-5-thieno[2,3-e][1,3]benzothiazolyl)oxy]-3-pyridinyl]sulfonyl]morpholinePlasmodium falciparum 3D7Potency4.228410
N-(2-bromophenyl)-2-[[2-(2,6-dimethylanilino)-2-oxoethyl]-methylamino]acetamidePlasmodium falciparum 3D7Potency6.309610
thioguanine anhydrousPlasmodium falciparum 3D7Potency25.118910
5-chloro-2-mercaptobenzothiazolePlasmodium falciparum 3D7Potency6.701610
4-amino-5-hydrazino-1,2,4-triazole-3-thiolPlasmodium falciparum 3D7Potency39.810710
diaminomaleonitrile, (z)-isomerPlasmodium falciparum 3D7Potency3.162310
4-bromotetramisole, oxalate (1:1), salt(s)-isomerPlasmodium falciparum 3D7Potency14.125410
mercaptopurinePlasmodium falciparum 3D7Potency8.912510
6-thioguanosinePlasmodium falciparum 3D7Potency5.623410
(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)-(2-chlorophenyl)methanonePlasmodium falciparum 3D7Potency0.631010
2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrilePlasmodium falciparum 3D7Potency1.584910
2-(1-adamantylcarbonyl)hydrazine-1-carbothioamidePlasmodium falciparum 3D7Potency3.548110
5-(2-chloroanilino)-3-oxo-4-isothiazolecarbonitrilePlasmodium falciparum 3D7Potency39.810710
N-(4-bromophenyl)-4-(2-methoxyphenyl)-1-piperidinecarbothioamidePlasmodium falciparum 3D7Potency22.387210
3-(9-carbazolylmethyl)-4-methyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency10.000010
1-[[2-[5-[3,5-bis(trifluoromethyl)phenyl]-2-tetrazolyl]-1-oxoethyl]amino]-3-(4-chlorophenyl)thioureaPlasmodium falciparum 3D7Potency2.511910
1-(3-methylphenyl)-3-(2-pyridinyl)thioureaPlasmodium falciparum 3D7Potency14.125410
5-(1-naphthalenylamino)-3H-1,3,4-thiadiazole-2-thionePlasmodium falciparum 3D7Potency5.623410
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency12.589310
tamoxifenPlasmodium falciparum 3D7Potency35.481310
3,4-di-O-acetyl-6-deoxy-L-glucalPlasmodium falciparum 3D7Potency3.548110
xanthane hydridePlasmodium falciparum 3D7Potency3.162310
3-Chloro-5-(trifluoromethyl)pyridine-2-carbothioamidePlasmodium falciparum 3D7Potency25.118910
1-(2,4-difluorophenyl)-3-[(5-methyl-3-phenyl-4-isoxazolyl)methyl]ureaPlasmodium falciparum 3D7Potency19.952610
2,6-dimethyl-4-(3-thienyl)pyridine-3,5-dicarboxylic acidPlasmodium falciparum 3D7Potency39.810710
N'-[(4-chlorophenyl)-oxomethyl]-2-thiophen-2-yl-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency3.162310
N'-[(4-chlorophenyl)-oxomethyl]-2-methyl-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency1.122010
N'-benzoyl-5-(3,5-dichlorophenoxy)-2-furancarbohydrazidePlasmodium falciparum 3D7Potency10.000010
5-cyano-2-(methoxymethyl)-6-sulfanylidene-1H-pyridine-3-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency31.622810
6-(2-methyl-3-imidazo[1,2-a]pyridinyl)-1H-pyrimidine-2-thionePlasmodium falciparum 3D7Potency11.220210
N-(2-chlorophenyl)-2-[[5-[5-(trifluoromethyl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]thio]acetamidePlasmodium falciparum 3D7Potency3.162310
N-(3-chlorophenyl)-2-[[2-(2-pyridinyl)-2,3-dihydro-1,3,4-thiadiazol-5-yl]thio]acetamidePlasmodium falciparum 3D7Potency39.810710
2-methoxy-4-[3-(2-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]phenolPlasmodium falciparum 3D7Potency10.000010
4-(2-furanyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
2-[bis(5-methyl-2-furanyl)methyl]-6-nitrophenolPlasmodium falciparum 3D7Potency31.622810
3-[[(2,4-dichlorophenyl)methylthio]methyl]-4-propan-2-yl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency2.238710
2-amino-6-[4-(6-chloro-2-pyridinyl)-1-piperazinyl]pyridine-3,5-dicarbonitrilePlasmodium falciparum 3D7Potency23.778110
[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]hydrazinePlasmodium falciparum 3D7Potency19.952610
4-(dimethylamino)-3-[(phenylmethoxyamino)methylideneamino]-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency10.000010
5-cyano-6-phenoxy-2-phenyl-3-pyridinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency22.387210
3-(methylthio)-4-oxo-6,7-dihydro-5H-2-benzothiophene-1-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency3.548110
4-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]morpholinePlasmodium falciparum 3D7Potency17.782810
2-[3-(4-pyridyl)-1H-1,2,4-triazol-5-yl]pyridinePlasmodium falciparum 3D7Potency17.782810
ssya10-001Plasmodium falciparum 3D7Potency15.848910
2,3-dichloro-N'-[4-(trifluoromethyl)-2-pyrimidinyl]benzenesulfonohydrazidePlasmodium falciparum 3D7Potency14.125410
(4-methylphenyl)-[4-[4-nitro-2-(1-pyrrolyl)phenyl]-1-piperazinyl]methanonePlasmodium falciparum 3D7Potency17.782810
N'-(4-tert-butyl-2-thiazolyl)-4-chlorobenzohydrazidePlasmodium falciparum 3D7Potency1.995310
N'-(3-chloro-4-methylphenyl)-5-isoxazolecarbohydrazidePlasmodium falciparum 3D7Potency22.387210
N-[3-(aminosulfonyl)phenyl]-2-phenoxynicotinamidePlasmodium falciparum 3D7Potency0.631010
4-fluoro-N-[2-(1-piperidinyl)phenyl]benzenesulfonamidePlasmodium falciparum 3D7Potency39.810710
3-[[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)thio]methyl]-4-prop-2-enyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency39.810710
4-(2-furanylmethyl)-3-[(3-methoxyphenyl)methyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency19.952610
3-oxo-2-[(5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)thio]butanoic acid ethyl esterPlasmodium falciparum 3D7Potency28.183810
5-[[(4-methoxyanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
3-(2,4-dimethoxyphenyl)-6-phenyl-2-sulfanylidene-1H-thieno[2,3-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency3.162310
N'-[4-(3-methoxyphenyl)-2-thiazolyl]-2-thiophenecarbohydrazidePlasmodium falciparum 3D7Potency1.412510
6-(2,3-dihydrobenzofuran-5-yl)-1H-pyrimidine-2-thionePlasmodium falciparum 3D7Potency25.118910
N'-benzoyl-2-(3-pyridinyl)-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency7.079510
1-tert-butyl-3-[(4-methylphenyl)sulfonylamino]thioureaPlasmodium falciparum 3D7Potency39.810710
2-(2-pyrenyl)acetonitrilePlasmodium falciparum 3D7Potency28.183810
(4-chloro-2-methylanilino)thioureaPlasmodium falciparum 3D7Potency39.810710
4-[[4-(3-methylanilino)-3,5-dinitrophenyl]-oxomethyl]-1,3-dihydroquinoxalin-2-onePlasmodium falciparum 3D7Potency28.183810
N'-[3-bicyclo[2.2.1]heptanyl(oxo)methyl]-3-chloro-1-benzothiophene-2-carbohydrazidePlasmodium falciparum 3D7Potency15.848910
3-benzylbenzothiazoliumPlasmodium falciparum 3D7Potency23.778110
5-cyclopentylidene-2-sulfanylidene-4-thiazolidinonePlasmodium falciparum 3D7Potency3.981110
4-phenyl-N-(pyridin-4-ylmethyl)-2-butanaminePlasmodium falciparum 3D7Potency29.934910
N-(2-methoxycyclohexyl)-3,4-dimethylanilinePlasmodium falciparum 3D7Potency18.887610
3,5,7-trimethyl-N-[4-morpholinyl(sulfanylidene)methyl]-1-adamantanecarboxamidePlasmodium falciparum 3D7Potency1.191710
N-(4-methylphenyl)-5-nitro-4-spiro[benzimidazole-2,1'-cyclohexane]aminePlasmodium falciparum 3D7Potency3.162310
3-methyl-2-[(4-methylphenyl)sulfonylamino]pentanoic acid (4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl) esterPlasmodium falciparum 3D7Potency1.337110
3,4-dimethyl-6-(6-nitro-1,3-benzodioxol-5-yl)-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid propyl esterPlasmodium falciparum 3D7Potency5.623410
(2-chlorophenyl)-(5-hydroxy-3-methyl-5-phenyl-4H-pyrazol-1-yl)methanonePlasmodium falciparum 3D7Potency1.995310
N'-[4-(1-adamantyl)-2-thiazolyl]-N-[(4-fluorophenyl)methyl]oxamidePlasmodium falciparum 3D7Potency15.848910
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamidePlasmodium falciparum 3D7Potency19.952610
2-methoxy-N-(2-pyridinylmethyl)-3-dibenzofuranaminePlasmodium falciparum 3D7Potency17.782810
[(2S)-1,3-dimethyl-3'-nitro-1'-spiro[cyclohepta[d]imidazol-3-ium-2,4'-cyclohexa-2,5-diene]ylidene]-dioxidoammoniumPlasmodium falciparum 3D7Potency7.943310
1-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]-4-phenylpiperazinePlasmodium falciparum 3D7Potency11.220210
N-[(2-ethyl-1-piperidinyl)-sulfanylidenemethyl]-4-nitrobenzamidePlasmodium falciparum 3D7Potency1.258910
N-(1-butyl-2-benzimidazolyl)cyclohexanecarboxamidePlasmodium falciparum 3D7Potency8.912510
4-chloro-3-(diethylsulfamoyl)-N-(2-nitrophenyl)benzamidePlasmodium falciparum 3D7Potency19.952610
N-[(2-ethyl-1-piperidinyl)-sulfanylidenemethyl]-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency0.891310
4-[[3-methoxy-4-[(4-nitrophenyl)methoxy]phenyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-onePlasmodium falciparum 3D7Potency28.183810
eskazinePlasmodium falciparum 3D7Potency35.481310
2-(2-hydroxyethylamino)-3-(4-methoxyanilino)naphthalene-1,4-dionePlasmodium falciparum 3D7Potency39.810710
N-[(5-chloro-8-hydroxy-7-quinolinyl)-(4-methoxyphenyl)methyl]acetamidePlasmodium falciparum 3D7Potency3.162310
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] esterPlasmodium falciparum 3D7Potency39.810710
4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-ethoxyphenyl] esterPlasmodium falciparum 3D7Potency23.778110
2-(3,4-dimethylphenyl)-5-ethyl-5-phenyl-1,2,4-triazolidine-3-thionePlasmodium falciparum 3D7Potency10.000010
2-[[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-methylamino]acetic acid methyl esterPlasmodium falciparum 3D7Potency28.183810
1-[2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]oxy]ethyl]-3-phenylureaPlasmodium falciparum 3D7Potency3.548110
1-[4-(3,4-dihydroxyphenyl)-6-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]ethanonePlasmodium falciparum 3D7Potency4.466810
2,6-dimethyl-4-thiophen-2-ylsulfonylmorpholinePlasmodium falciparum 3D7Potency23.778110
1-[[2-(2,4-difluorophenoxy)-1-oxopropyl]amino]-3-(2-oxolanylmethyl)thioureaPlasmodium falciparum 3D7Potency2.818410
3-(2-furanyl)-3-(4-methylphenyl)-1-(4-morpholinyl)-1-propanonePlasmodium falciparum 3D7Potency19.952610
N-[1-oxo-3-phenyl-1-(2-pyridinylmethylamino)propan-2-yl]-2-furancarboxamidePlasmodium falciparum 3D7Potency28.183810
N-(4-nitrophenyl)-2-(1-pyrrolidinyl)acetamidePlasmodium falciparum 3D7Potency6.309610
5-chloro-7-[3-pyridinyl-(2-pyridinylamino)methyl]-8-quinolinolPlasmodium falciparum 3D7Potency17.782810
4-[cyclohexyl(methyl)amino]-N-(6-methyl-2-pyridinyl)-3-nitrobenzamidePlasmodium falciparum 3D7Potency11.220210
cb 7969312Plasmodium falciparum 3D7Potency3.162310
2-[(4-methylphenyl)thio]-N-(1H-1,2,4-triazol-5-yl)propanamidePlasmodium falciparum 3D7Potency15.848910
7-ethyl-7-methyl-2-sulfanylidene-6,9-dihydro-1H-pyrano[2,3]thieno[2,4-b]pyrimidin-4-onePlasmodium falciparum 3D7Potency7.943310
2-[1-[[[(3-chloro-1-benzothiophen-2-yl)-oxomethyl]amino]-sulfanylidenemethyl]-3-oxo-2-piperazinyl]acetic acid methyl esterPlasmodium falciparum 3D7Potency2.818410
4-[1-(4-fluorophenyl)ethyl]-3-thiophen-2-yl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency25.118910
2-[3-oxo-1-[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]-2-piperazinyl]acetic acid propan-2-yl esterPlasmodium falciparum 3D7Potency7.943310
2-[1-[[[(4-methoxyphenyl)-oxomethyl]amino]-sulfanylidenemethyl]-3-oxo-2-piperazinyl]acetic acid propan-2-yl esterPlasmodium falciparum 3D7Potency3.162310
5-(2-nitrophenyl)-N-(2-thiazolyl)-2-furancarboxamidePlasmodium falciparum 3D7Potency10.000010
2-methyl-1-cyclopropanecarboxylic acid (7-bromo-4-oxo-2-pyrido[1,2-a]pyrimidinyl)methyl esterPlasmodium falciparum 3D7Potency14.125410
2-[[5-[(2-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamidePlasmodium falciparum 3D7Potency0.946610
N-(3-methyl-1,3-benzothiazol-2-ylidene)-2-pyrazinecarboxamidePlasmodium falciparum 3D7Potency4.466810
4-chloro-N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency0.707910
5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid [2-[(1,1-dioxo-3-thiolanyl)-(2-methylpropyl)amino]-2-oxoethyl] esterPlasmodium falciparum 3D7Potency28.183810
3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazinePlasmodium falciparum 3D7Potency39.810710
3-[[5,5-dimethyl-3-(4-morpholinyl)-1-cyclohex-2-enylidene]amino]-N,N-dimethylanilinePlasmodium falciparum 3D7Potency7.079510
9-phenyl-1,5,6,7,8,9-hexahydro-[1,2,4]triazolo[5,1-b]quinazolinePlasmodium falciparum 3D7Potency37.685810
N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency0.422810
nsc 336628Plasmodium falciparum 3D7Potency35.481310
6-mercapto-9-(tetrahydro-2-furyl)purinePlasmodium falciparum 3D7Potency14.125410
ly 73497Plasmodium falciparum 3D7Potency1.584910
2-amino-9-pentyl-3H-purine-6-thionePlasmodium falciparum 3D7Potency3.548110
alpha-sarcinPlasmodium falciparum 3D7Potency39.810710
p-201-1Plasmodium falciparum 3D7Potency22.387210
thiophanatePlasmodium falciparum 3D7Potency15.848910
zuclomifene citratePlasmodium falciparum 3D7Potency22.387210
9-cyclopentyl-3H-purine-6-thionePlasmodium falciparum 3D7Potency11.220210
9-(n-butyl)-6-thioguaninePlasmodium falciparum 3D7Potency12.589310
1,3-dimethyl-8-[2-(1-pyrrolidinyl)ethylthio]-6-sulfanylidene-7H-purin-2-onePlasmodium falciparum 3D7Potency8.912510
asterric acidPlasmodium falciparum 3D7Potency8.912510
2,2-dimethyl-N-[2,2,2-trichloro-1-(2-pyrimidinylthio)ethyl]propanamidePlasmodium falciparum 3D7Potency25.118910
N-methyl-5-nitro-N-(phenylmethyl)-2-furancarboxamidePlasmodium falciparum 3D7Potency14.125410
N-tert-butyl-2-[[(3-nitrophenyl)-oxomethyl]hydrazo]-2-oxoacetamidePlasmodium falciparum 3D7Potency25.118910
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-(3-methylphenyl)acetamidePlasmodium falciparum 3D7Potency39.810710
2-(2,2-dimethyl-4-oxanyl)-4-(4-nitrophenyl)thiazolePlasmodium falciparum 3D7Potency19.952610
2-[[2-(4-chlorophenoxy)-1-oxoethyl]hydrazo]-N-(2-methoxy-5-methylphenyl)-2-oxoacetamidePlasmodium falciparum 3D7Potency1.258910
(3-bromophenyl)-[5-(4-bromophenyl)-3-ethyl-5-hydroxy-4H-pyrazol-1-yl]methanonePlasmodium falciparum 3D7Potency0.707910
4-methyl-2-[3-methyl-4-(3-methylphenyl)azo-5-oxo-4H-pyrazol-1-yl]-5-thiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency28.183810
4-methyl-3-phenyl-1H-pyrazole-5-carbohydrazidePlasmodium falciparum 3D7Potency10.000010
2-[(4-chlorophenyl)-[2-[5-(4-chlorophenyl)-2-thiazolyl]-5-methyl-3-oxo-1H-pyrazol-4-yl]methyl]propanedinitrilePlasmodium falciparum 3D7Potency3.162310
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazolePlasmodium falciparum 3D7Potency35.481310
2-[[2-(2,4-dichlorophenoxy)-1-oxopropyl]hydrazo]-N-(4-methoxyphenyl)-2-oxoacetamidePlasmodium falciparum 3D7Potency4.466810
2-(2-bromophenyl)-2,3-dihydro-1H-perimidinePlasmodium falciparum 3D7Potency25.118910
1-[5-hydroxy-3-methyl-5-(3-pyridinyl)-4H-pyrazol-1-yl]-2-(4-methylphenyl)ethanonePlasmodium falciparum 3D7Potency3.548110
N'-[(2-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazidePlasmodium falciparum 3D7Potency0.707910
N'-[2-(4-methylphenoxy)-1-oxoethyl]-2-(5-phenyl-2-tetrazolyl)acetohydrazidePlasmodium falciparum 3D7Potency1.584910
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency16.833610
N-[[5-[(4-chlorophenyl)methylthio]-4-phenyl-1,2,4-triazol-3-yl]methyl]-4-ethoxyanilinePlasmodium falciparum 3D7Potency31.622810
2-(3,4-dimethoxyphenyl)-1-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]ethanonePlasmodium falciparum 3D7Potency25.118910
4-(6-bromo-1,3-benzodioxol-5-yl)-7,9-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolinePlasmodium falciparum 3D7Potency19.952610
3-nitro-N-[(1-oxopentylhydrazo)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency7.943310
N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamidePlasmodium falciparum 3D7Potency0.707910
1-[(2-ethyl-4-hydroxy-4-methyl-1-oxopentyl)amino]-3-phenylthioureaPlasmodium falciparum 3D7Potency2.511910
N'-[2-[(6-methoxy-2-methyl-4-quinolinyl)thio]-1-oxoethyl]-2-(1-naphthalenyloxy)acetohydrazidePlasmodium falciparum 3D7Potency1.000010
N-(2,5-dimethoxyphenyl)-4-(2,4-dimethyl-5-thiazolyl)-2-thiazolaminePlasmodium falciparum 3D7Potency14.125410
5-methyl-1-[3-(2-methylphenoxy)propyl]indole-2,3-dionePlasmodium falciparum 3D7Potency39.810710
N'-[2-[(4-amino-5-cyano-2-pyrimidinyl)thio]-1-oxoethyl]-2-(4-methylphenoxy)acetohydrazidePlasmodium falciparum 3D7Potency10.000010
1-(2-furanylmethyl)-3-[[[4-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
4-[[(4-tert-butylphenyl)-oxomethyl]hydrazo]-N-(5-methyl-3-isoxazolyl)-4-oxobutanamidePlasmodium falciparum 3D7Potency19.952610
7'-hydroxy-4'-(4-methoxyphenyl)-4,4,5'-trimethyl-2-spiro[1,3-diazinane-6,2'-3,4-dihydro-2H-1-benzopyran]thionePlasmodium falciparum 3D7Potency39.810710
N-[2-(tert-butylamino)-2-oxo-1-thiophen-2-ylethyl]-N-(2-oxolanylmethyl)-5-phenyl-1H-pyrrole-2-carboxamidePlasmodium falciparum 3D7Potency31.622810
4-[[4-(1,3-benzothiazol-2-yl)-1-piperazinyl]-[1-(2-phenylethyl)-5-tetrazolyl]methyl]phenolPlasmodium falciparum 3D7Potency17.782810
2-butyl-3-[(3-chlorophenyl)methyl]-5-methyl-6-imidazo[4,5-b]pyridinaminePlasmodium falciparum 3D7Potency19.952610
N'-[2-[(2-cyclohexyl-4-quinazolinyl)thio]-1-oxoethyl]-2-methylpropanehydrazidePlasmodium falciparum 3D7Potency0.707910
2-[[5-(4-fluorophenyl)-1-methyl-2-imidazolyl]thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanonePlasmodium falciparum 3D7Potency1.778310
N-(1,3-benzodioxol-5-ylmethyl)-N-[2-(cyclohexylamino)-2-oxo-1-pyridin-4-ylethyl]-2,2,2-trifluoroacetamidePlasmodium falciparum 3D7Potency31.622810
1-methyl-4-[2-oxo-2-(N-(phenylmethyl)anilino)ethyl]-5-pyrrolo[3,2-b]pyrrolecarboxylic acid propan-2-yl esterPlasmodium falciparum 3D7Potency28.183810
2-[5-[[2-(3-methoxypropylamino)-2-oxoethyl]thio]-3-oxo-2H-imidazo[1,2-c]quinazolin-2-yl]-N-(phenylmethyl)acetamidePlasmodium falciparum 3D7Potency3.358710
3-[6-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-6-oxohexyl]-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency39.810710
5-bromo-N-[6-[[(5-bromo-2-furanyl)-oxomethyl]amino]-2-pyridinyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency26.679510
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency8.912510
2-[(3-methoxyphenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency5.323310
6-bromo-3-[4-oxo-4-[4-(2-pyridinyl)-1-piperazinyl]butyl]-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency9.466210
2-phenyl-5-(1-piperidinyl)-4-triazolecarbonitrilePlasmodium falciparum 3D7Potency35.481310
1-(4-chlorophenyl)sulfonyl-N-(2-thiazolyl)-1-cyclopropanecarboxamidePlasmodium falciparum 3D7Potency29.934910
4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamidePlasmodium falciparum 3D7Potency33.587510
1-(2-methoxyethyl)-2-[(4-methylphenoxy)methyl]benzimidazolePlasmodium falciparum 3D7Potency4.466810
2-(N-ethylanilino)-4-thieno[3,2-d][1,3]thiazinonePlasmodium falciparum 3D7Potency39.810710
3-[4-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-4-oxobutyl]-6,7-diethoxy-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency21.192310
1-[[1-(2-methoxyanilino)-4-isoquinolinyl]-oxomethyl]-4-piperidinecarboxamidePlasmodium falciparum 3D7Potency39.810710
N-[4-[[4-(2-fluorophenyl)-1-piperazinyl]-oxomethyl]-1-oxo-2-isoquinolinyl]-2-pyrazinecarboxamidePlasmodium falciparum 3D7Potency2.511910
5-(6,7-diethoxy-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)-N-(2-furanylmethyl)pentanamidePlasmodium falciparum 3D7Potency37.685810
6-chloro-3-[2-(diethylamino)ethyl]-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency9.466210
4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-imidazo[1,2-a]pyrimidinyl]phenolPlasmodium falciparum 3D7Potency28.183810
2-amino-4-[5-methyl-2-(methylthio)-3-thiophenyl]-5-oxo-1-(3-pyridinyl)-4,6,7,8-tetrahydroquinoline-3-carbonitrilePlasmodium falciparum 3D7Potency1.683410
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanonePlasmodium falciparum 3D7Potency14.125410
6,7-diethoxy-3-(3-methoxypropyl)-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency7.519310
6-(1-azepanylsulfonyl)-1-ethyl-N-(2-furanylmethyl)-4-oxo-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency1.995310
N-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]cyclopropanecarboxamidePlasmodium falciparum 3D7Potency39.810710
7-(5-chloro-2-methoxyanilino)-6-[(4-methoxyphenyl)methyl]-7H-pyrrolo[3,4-b]pyridin-5-onePlasmodium falciparum 3D7Potency26.679510
5-amino-1-(3,5-dimethylphenyl)-N-(phenylmethyl)-4-triazolecarboxamidePlasmodium falciparum 3D7Potency7.079510
N-[[4-(dimethylamino)phenyl]methyl]-3-ethyl-N-(2-furanylmethyl)-5-methyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamidePlasmodium falciparum 3D7Potency39.810710
N-butan-2-yl-6-[(4-ethoxyphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamidePlasmodium falciparum 3D7Potency39.810710
7-[4-[4-(2-fluorophenyl)-1-piperazinyl]-4-oxobutyl]-6-sulfanylidene-5H-[1,3]dioxolo[4,5-g]quinazolin-8-onePlasmodium falciparum 3D7Potency3.358710
N-cycloheptyl-3-(5,7-dioxo-6-pyrrolo[3,4-b]pyridinyl)propanamidePlasmodium falciparum 3D7Potency17.782810
3-methyl-5-(4-morpholinylsulfonyl)-N-(2-pyridinylmethyl)-2-benzofurancarboxamidePlasmodium falciparum 3D7Potency15.848910
3-hydroxy-2-(2-hydroxy-3-methoxyphenyl)-1,2-dihydroquinazolin-4-onePlasmodium falciparum 3D7Potency3.162310
[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]-[4-(2-pyridinyl)-1-piperazinyl]methanonePlasmodium falciparum 3D7Potency28.183810
N-[[3-[(3-chlorophenyl)sulfamoyl]-4-methylanilino]-sulfanylidenemethyl]-4-fluorobenzamidePlasmodium falciparum 3D7Potency2.818410
2,6-dimethyl-4-(4-phenyl-2-quinolinyl)morpholinePlasmodium falciparum 3D7Potency17.782810
N-[[4-(dimethylamino)phenyl]methyl]-1-ethyl-5-benzimidazolaminePlasmodium falciparum 3D7Potency12.589310
3-[3-(N-ethylanilino)propyl]-6-(4-morpholinyl)-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency7.079510
8-[(1-ethyl-3-piperidinyl)thio]-1,3-dimethyl-6-sulfanylidene-7H-purin-2-onePlasmodium falciparum 3D7Potency22.387210
3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamidePlasmodium falciparum 3D7Potency3.548110
2-pyridinecarboxylic acid [2-(5-chloro-2-thiophenyl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency7.079510
4-(1-azepanyl)-6-hydrazinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-aminePlasmodium falciparum 3D7Potency11.220210
3-(5-ethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.548110
N-(5-acetyl-2-phenyl-4-sulfanylidene-1H-pyrimidin-6-yl)benzamidePlasmodium falciparum 3D7Potency39.810710
3-amino-4-(1,3-benzothiazol-2-yl)-N-(3-chloro-2-methylphenyl)-5-phenylimino-2H-thiophene-2-carboxamidePlasmodium falciparum 3D7Potency7.079510
N'-[5-(phenylmethyl)-4,5-dihydrothiazol-2-yl]hexanehydrazidePlasmodium falciparum 3D7Potency1.995310
2-amino-7-methyl-4-(5-nitro-2-furanyl)-5-oxo-4H-pyrano[3,2-c]pyran-3-carbonitrilePlasmodium falciparum 3D7Potency1.258910
3-(1-methyl-2-benzimidazolyl)-1-phenyl-2-pyrrolo[3,2-b]quinoxalinaminePlasmodium falciparum 3D7Potency1.995310
2-phenoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]acetamidePlasmodium falciparum 3D7Potency2.238710
LSM-19878Plasmodium falciparum 3D7Potency19.952610
2-[(4-cyano-1-oxo-5H-pyrido[1,2-a]benzimidazol-3-yl)methylthio]propanoic acidPlasmodium falciparum 3D7Potency19.952610
N,N,1-triethyl-2-sulfanylidene-3H-benzimidazole-5-sulfonamidePlasmodium falciparum 3D7Potency25.118910
5-[[(3,4-dichloroanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency0.316210
2-methyl-N'-[2-[(5-methyl-4-phenyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]benzohydrazidePlasmodium falciparum 3D7Potency8.912510
N-[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]benzenesulfonamidePlasmodium falciparum 3D7Potency17.782810
5-(3-nitrophenyl)-3-phenyl-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency6.309610
1-(3,4-dichlorophenyl)-3-[1-(4-morpholinyl)-1-phenylpropan-2-yl]ureaPlasmodium falciparum 3D7Potency5.011910
ro 41-0960Plasmodium falciparum 3D7Potency12.589310
1-[(3-chlorophenyl)methyl]-N-methyl-N-(phenylmethyl)-3-piperidinecarboxamidePlasmodium falciparum 3D7Potency7.079510
4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)-N-(5-ethyl-1,3,4-oxadiazol-2-yl)benzamidePlasmodium falciparum 3D7Potency0.532310
3-(3-chloro-2-methylphenyl)-1-[(4-methylphenyl)methyl]-1-(3-pyridinylmethyl)thioureaPlasmodium falciparum 3D7Potency22.387210
2-(2,4-dibromophenoxy)-N-[[3-(hydroxymethyl)anilino]-sulfanylidenemethyl]acetamidePlasmodium falciparum 3D7Potency25.118910
5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-8-(3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-4H-chromen-4-onePlasmodium falciparum 3D7Potency35.481310
[1-[2-(2-methylphenoxy)ethyl]-3-indolyl]-(4-methyl-1-piperazinyl)methanethionePlasmodium falciparum 3D7Potency25.118910
1-(4-butylphenyl)-3-[4-chloro-3-(dimethylsulfamoyl)phenyl]thioureaPlasmodium falciparum 3D7Potency5.011910
8-methylene-7-(phenylmethyl)-5H-[1,3]dioxolo[4,5-g]quinazoline-6-thionePlasmodium falciparum 3D7Potency11.220210
1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]ureaPlasmodium falciparum 3D7Potency31.622810
4-chloro-N-[5-(2,3-dihydro-1,4-dioxin-5-yl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency2.238710
2-methyl-1,3-bis(phenylmethoxy)benzenePlasmodium falciparum 3D7Potency28.183810
3-(1,3-benzothiazol-2-ylhydrazo)-1-(4-ethylphenyl)pyrrolidine-2,5-dionePlasmodium falciparum 3D7Potency31.622810
N'-[(3-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazidePlasmodium falciparum 3D7Potency1.412510
6,8-dibromo-2-thiophen-2-ylquinolinePlasmodium falciparum 3D7Potency31.622810
5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dionePlasmodium falciparum 3D7Potency39.810710
4-[1-oxo-6-(4-oxo-2-sulfanylidene-1H-thieno[3,2-d]pyrimidin-3-yl)hexyl]-1-piperazinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency7.943310
3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.162310
1-(4-chlorophenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]ureaPlasmodium falciparum 3D7Potency12.589310
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazidePlasmodium falciparum 3D7Potency5.011910
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazolePlasmodium falciparum 3D7Potency25.118910
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]-2-thiophenesulfonamidePlasmodium falciparum 3D7Potency3.981110
3-ethyl-2-sulfanylidene-5-thiophen-2-yl-1H-thieno[2,3-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency2.818410
5-nitro-2-mercaptobenzimidazolePlasmodium falciparum 3D7Potency31.622810
6-[(4-bromophenyl)-(1-pyrrolidinyl)methyl]-1,3-benzodioxol-5-olPlasmodium falciparum 3D7Potency22.387210
4-[[anilino-(4-methylphenyl)methyl]-propoxyphosphoryl]-N,N-dimethylanilinePlasmodium falciparum 3D7Potency15.848910
6-amino-3-(3-methoxyphenyl)-4-(3-thiophenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrilePlasmodium falciparum 3D7Potency25.118910
N-tert-butyl-1-hydroxy-5-nitro-4-spiro[benzimidazole-2,1'-cyclohexane]iminePlasmodium falciparum 3D7Potency2.818410
5-methyl-3-phenyl-7-(prop-2-enylthio)pyrazolo[1,5-a]pyrimidinePlasmodium falciparum 3D7Potency19.952610
1-ethyl-3-[[2-[(1-methyl-2-benzimidazolyl)thio]-1-oxoethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.891310
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl esterPlasmodium falciparum 3D7Potency13.371410
8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trionePlasmodium falciparum 3D7Potency22.387210
4-(2-methylcyclohexyl)-3-(3-pyridinyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency2.818410
7-chloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinonePlasmodium falciparum 3D7Potency11.220210
4-[[[2-(4-methoxyphenyl)-3-thiazolidinyl]-sulfanylidenemethyl]amino]benzoic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
4-fluoro-N-[[2-(3-pyridinyl)-1-piperidinyl]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency3.162310
5,7-dimethyl-3-phenyldiazenyl-1H-pyrazolo[1,5-a]pyrimidin-2-onePlasmodium falciparum 3D7Potency35.481310
4-chloro-N-[3-(3-methyl-1-piperidinyl)-1,4-dioxo-2-naphthalenyl]benzenesulfonamidePlasmodium falciparum 3D7Potency3.162310
6-(5,6-Dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acidPlasmodium falciparum 3D7Potency19.952610
2-(4-phenyl-1-piperazinyl)quinoxalinePlasmodium falciparum 3D7Potency10.000010
5-methyl-2-[[(4-nitrophenyl)-oxomethyl]hydrazo]-4-thiazolecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency3.162310
2-amino-7,7-dimethyl-4-(4-methylphenyl)-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbothioamidePlasmodium falciparum 3D7Potency2.238710
1-(phenylmethyl)-4-(phenylmethylthio)pyrazolo[3,4-d]pyrimidinePlasmodium falciparum 3D7Potency28.183810
N-[[[(4-fluorophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency10.000010
N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamidePlasmodium falciparum 3D7Potency0.707910
6-nitro-3-phenyl-1H-benzimidazole-2-thionePlasmodium falciparum 3D7Potency35.481310
or486Plasmodium falciparum 3D7Potency22.387210
2-(1H-benzimidazol-2-yl)-5-methyl-4-(phenylmethyl)-4H-pyrazol-3-onePlasmodium falciparum 3D7Potency2.818410
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-methyl-2,5-dioxo-4-(2-phenylethyl)-1-imidazolidinyl]acetamidePlasmodium falciparum 3D7Potency0.794310
N-(1,3-benzothiazol-2-yl)-2-ethylsulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamidePlasmodium falciparum 3D7Potency17.782810
N-[2-(4-fluorophenyl)ethyl]-2-[2-(2-hydroxyethylamino)-1-benzimidazolyl]acetamidePlasmodium falciparum 3D7Potency3.981110
1-(1H-indol-3-yl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanonePlasmodium falciparum 3D7Potency39.810710
N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-N-ethyl-2-(2-methyl-2,3-dihydroindol-1-yl)acetamidePlasmodium falciparum 3D7Potency1.778310
4-benzoyl-2-heptyl-5-methyl-4H-pyrazol-3-onePlasmodium falciparum 3D7Potency19.952610
vu0155094Plasmodium falciparum 3D7Potency31.622810
N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]cyclohexanecarboxamidePlasmodium falciparum 3D7Potency2.818410
N-(2,4-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamidePlasmodium falciparum 3D7Potency39.810710
3-(2-chlorophenyl)-N-[5-(2,4-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-4-isoxazolecarboxamidePlasmodium falciparum 3D7Potency28.183810
1-butyl-3-[[2-furanyl(oxo)methyl]amino]thioureaPlasmodium falciparum 3D7Potency0.631010
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(4-fluorophenyl)-2-(2-methoxyethyl)-1-oxo-3,4-dihydroisoquinoline-4-carboxamidePlasmodium falciparum 3D7Potency8.912510
1-[(1,2-dimethyl-5-indolyl)methyl]-3-(phenylmethyl)thioureaPlasmodium falciparum 3D7Potency25.118910
6-(4-morpholinyl)-3-(2-phenylethyl)-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency3.162310
N-(1,3-benzodioxol-5-ylmethyl)-6-[6-(4-morpholinyl)-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl]hexanamidePlasmodium falciparum 3D7Potency0.891310
N-[4-oxo-2-(2-pyridinyl)-1,2-dihydroquinazolin-3-yl]acetamidePlasmodium falciparum 3D7Potency3.162310
3,5-bis(4-methoxyphenyl)-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency3.548110
4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency7.519310
2-bromo-N-[[(2-methylcyclohexyl)amino]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency8.912510
4-(4-ethoxyphenyl)-1-(4-methoxyphenyl)-2-(methylthio)imidazolePlasmodium falciparum 3D7Potency22.387210
N-(5-phenyl-1,3,4-oxadiazol-2-yl)-1,3-benzothiazole-2-carboxamidePlasmodium falciparum 3D7Potency3.548110
3-nitro-N-[(3-sulfamoylanilino)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency28.183810
N-(1,3-diphenylpropan-2-ylideneamino)-2-hydroxybenzamidePlasmodium falciparum 3D7Potency6.309610
3-(2-fluorophenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency15.848910
2-(4-ethoxyphenyl)-1-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]ethanonePlasmodium falciparum 3D7Potency22.387210
1-(2-methylphenyl)-3-(6,7,8,9-tetrahydro-5H-carbazol-3-ylmethyl)thioureaPlasmodium falciparum 3D7Potency11.220210
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(4-propan-2-ylphenyl)-4-quinolinyl]methanonePlasmodium falciparum 3D7Potency15.848910
1-[[4-anilino-6-(1-piperidinyl)-1,3,5-triazin-2-yl]amino]-3-cyclohexylthioureaPlasmodium falciparum 3D7Potency0.707910
7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidinePlasmodium falciparum 3D7Potency44.668410
2-[1-[4-(diethylamino)phenyl]-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-phenylacetamidePlasmodium falciparum 3D7Potency3.162310
3-chloro-N-[5-(3-pyridinyl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency1.584910
6-amino-5-cyano-2-[[(3-cyano-6-methyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)thio]methyl]-4-(4-fluorophenyl)-4H-pyran-3-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency9.466210
5-[[(2-methylanilino)-sulfanylidenemethyl]amino]-1H-pyrazole-4-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency1.500310
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)benzohydrazidePlasmodium falciparum 3D7Potency0.707910
N-(2,5-dimethoxyphenyl)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1H-quinazoline-7-carboxamidePlasmodium falciparum 3D7Potency8.912510
N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-5-methyl-3-phenyl-4-isoxazolecarboxamidePlasmodium falciparum 3D7Potency6.309610
2-[4-(dimethylamino)phenyl]azobenzoic acid [2-(1-azepanyl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency17.782810
4-(3-chlorophenyl)sulfonyl-N-cyclohexyl-N-methyl-3-nitrobenzamidePlasmodium falciparum 3D7Potency10.000010
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(3-methyl-1-piperidinyl)sulfonyl]benzamidePlasmodium falciparum 3D7Potency2.511910
3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency22.387210
5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamidePlasmodium falciparum 3D7Potency22.387210
N-[2-(2,4,6-trinitrophenyl)ethyl]anilinePlasmodium falciparum 3D7Potency39.810710
5H-phenanthridine-6-thionePlasmodium falciparum 3D7Potency2.818410
2,4-dichloro-N-[(2,8-dimethyl-3,4,4a,9b-tetrahydro-1H-pyrido[4,3-b]indol-5-yl)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency3.162310
1-benzoyl-5-hydroxy-5-(4-methylphenyl)-4H-pyrazole-3-carboxylic acid ethyl esterPlasmodium falciparum 3D7Potency3.981110
2-[4-[[[[(2,4-dichlorophenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]-3-methylphenyl]-3,3,3-trifluoro-2-hydroxypropanoic acid ethyl esterPlasmodium falciparum 3D7Potency3.548110
1-[(2-fluorophenyl)methyl]-4-pyrazolaminePlasmodium falciparum 3D7Potency19.952610
2-chloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency3.162310
N-(cyclopentylideneamino)-4-(2,5-dimethyl-1-pyrrolyl)benzamidePlasmodium falciparum 3D7Potency28.183810
2-furanyl-[4-[(6-hydroxy-2-methyl-5-thiazolo[3,2-b][1,2,4]triazolyl)-thiophen-2-ylmethyl]-1-piperazinyl]methanonePlasmodium falciparum 3D7Potency19.952610
6-(2,3-dihydro-1,4-benzodioxin-3-yl)-3-(phenoxymethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazolePlasmodium falciparum 3D7Potency15.848910
N2,N6-bis[4-(dimethylamino)phenyl]pyridine-2,6-dicarboxamidePlasmodium falciparum 3D7Potency10.000010
4-bromo-N-[(2,8-dimethyl-3,4,4a,9b-tetrahydro-1H-pyrido[4,3-b]indol-5-yl)-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency2.818410
N-[2-(4-methoxyphenyl)ethyl]-2-nitro-4-(1-pyrrolidinylsulfonyl)anilinePlasmodium falciparum 3D7Potency12.589310
N-[5-(phenylmethyl)-2-thiazolyl]-4,5-dihydro-1H-imidazole-2-carboxamidePlasmodium falciparum 3D7Potency5.623410
2-(4-chlorophenoxy)-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]acetamidePlasmodium falciparum 3D7Potency1.778310
2,6-difluoro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency8.912510
isovitexinPlasmodium falciparum 3D7Potency3.548110
mucronulatolPlasmodium falciparum 3D7Potency39.810710
7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecanePlasmodium falciparum 3D7Potency3.981110
N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-4-[(2-methyl-1-piperidinyl)sulfonyl]benzamidePlasmodium falciparum 3D7Potency2.818410
4-[7-(2-methoxyethyl)-2,6-dioxo-3-(phenylmethyl)-8-purinyl]benzonitrilePlasmodium falciparum 3D7Potency11.220210
3-amino-4-[(4-chlorophenyl)thio]benzoic acid methyl esterPlasmodium falciparum 3D7Potency28.183810
1-[3-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acidPlasmodium falciparum 3D7Potency19.952610
N-(1H-benzimidazol-2-yl)-3-phenylbutanamidePlasmodium falciparum 3D7Potency31.622810
3-amino-N2-(2,3-dichlorophenyl)-5-(2-methoxyphenyl)imino-2H-thiophene-2,4-dicarboxamidePlasmodium falciparum 3D7Potency28.183810
N-[(3,5-dimethyl-1-piperidinyl)-sulfanylidenemethyl]-2-methyl-5-(4-morpholinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency2.818410
3-(4-ethoxyphenyl)-N-[(1-methyl-4-piperidinylidene)amino]-1H-pyrazole-5-carboxamidePlasmodium falciparum 3D7Potency39.810710
6-(6-bromo-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)-N-[2-(4-sulfamoylphenyl)ethyl]hexanamidePlasmodium falciparum 3D7Potency2.238710
ly 367265Plasmodium falciparum 3D7Potency35.481310
2,4-dichloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency3.162310
2-(1,3-dimethyl-2,6-dioxo-7-purinyl)-N'-[2-(2-ethoxyphenoxy)-1-oxoethyl]acetohydrazidePlasmodium falciparum 3D7Potency19.952610
2-(2-furanyl)-4-mercapto-3-(4-methylphenyl)-6-oxo-1,2-dihydropyrimidine-5-carbonitrilePlasmodium falciparum 3D7Potency22.387210
5-bromo-N-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)-2-thiophenecarboxamidePlasmodium falciparum 3D7Potency8.912510
4-chloro-N-[3-(N-methylanilino)-1,4-dioxo-2-naphthalenyl]benzamidePlasmodium falciparum 3D7Potency10.000010
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-2-(2-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamidePlasmodium falciparum 3D7Potency2.377810
4-(5-methyl-1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)benzoic acid 8-quinolinyl esterPlasmodium falciparum 3D7Potency3.981110
4-(4-chlorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency3.768610
[4-[(4-bromo-3,5-dimethyl-1-pyrazolyl)methyl]phenyl]-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanonePlasmodium falciparum 3D7Potency1.412510
2-(4-bromophenoxy)-N'-[2-[(4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]acetohydrazidePlasmodium falciparum 3D7Potency3.548110
8-nitro-5-[3-(trifluoromethyl)-1-piperidinyl]isoquinolinePlasmodium falciparum 3D7Potency19.952610
1-(2-chloro-4-nitrophenyl)-4-(2-methoxyphenyl)piperazinePlasmodium falciparum 3D7Potency22.387210
1-(2,4-difluorophenyl)-3-[4-(2-pyridinyl)-2-thiazolyl]ureaPlasmodium falciparum 3D7Potency1.995310
1-(4-methoxyphenyl)-3-[3-(1-piperidinylsulfonyl)phenyl]thioureaPlasmodium falciparum 3D7Potency2.818410
4-ethylbenzoic acid [2-(2-ethoxyanilino)-2-oxo-1-phenylethyl] esterPlasmodium falciparum 3D7Potency10.000010
1-[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]-3-[3-(dimethylamino)propyl]thioureaPlasmodium falciparum 3D7Potency31.622810
3-[(2,6-dimethyl-4-morpholinyl)sulfonyl]-N-(5-methyl-2-thiazolyl)benzamidePlasmodium falciparum 3D7Potency28.183810
4-(4-chlorophenyl)-3-(phenylmethyl)-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency6.309610
N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamidePlasmodium falciparum 3D7Potency39.810710
6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamidePlasmodium falciparum 3D7Potency3.548110
N-(1H-benzimidazol-2-yl)-2-nitrobenzamidePlasmodium falciparum 3D7Potency10.000010
2-[(2-chlorophenyl)methoxy]-N-(4,5-dihydrothiazol-2-yl)benzamidePlasmodium falciparum 3D7Potency39.810710
N-(1H-benzimidazol-2-yl)-3-(1-imidazolyl)propanamidePlasmodium falciparum 3D7Potency22.387210
2-methyl-1-cyclopropanecarboxylic acid [5-[2-(3,4-dimethoxyphenyl)-4-quinolinyl]-1,3,4-oxadiazol-2-yl]methyl esterPlasmodium falciparum 3D7Potency12.589310
5'-bromo-2'-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]onePlasmodium falciparum 3D7Potency2.818410
N-[3-[(4-chlorophenyl)methylthio]-1H-1,2,4-triazol-5-yl]-4-cyanobenzamidePlasmodium falciparum 3D7Potency1.000010
N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-aminePlasmodium falciparum 3D7Potency25.118910
4-[(2-cyano-1-oxoethyl)amino]benzoic acid [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl] esterPlasmodium falciparum 3D7Potency7.079510
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[[2-(2-pyridinyl)-1-benzimidazolyl]methyl]-1H-1,2,4-triazole-5-thionePlasmodium falciparum 3D7Potency28.183810
3-(1-methyl-2-benzimidazolyl)-1-(3-methylphenyl)-2-pyrrolo[3,2-b]quinoxalinaminePlasmodium falciparum 3D7Potency10.000010
LSM-25804Plasmodium falciparum 3D7Potency0.631010
6-(4-methoxyphenyl)-8-methyl-4-oxo-6H-pyrimido[2,1-b][1,3]thiazine-2,7-dicarboxylic acid O7-ethyl ester O2-methyl esterPlasmodium falciparum 3D7Potency3.548110
5-nitro-N-[(4-propan-2-ylphenyl)methyl]-2-pyridinaminePlasmodium falciparum 3D7Potency3.548110
3-(2-methoxyphenyl)-4-phenyl-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency19.952610
5-(3-chloroanilino)-3H-1,3,4-thiadiazole-2-thionePlasmodium falciparum 3D7Potency35.481310
4-(4-methylphenyl)-3-phenyl-1H-imidazole-2-thionePlasmodium falciparum 3D7Potency10.000010
5-carbamoyl-4-methyl-2-[[1-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]amino]-3-thiophenecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency19.952610
7-chloro-3-[2-(1-cyclohexenyl)ethyl]-2-sulfanylidene-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency2.238710
3-[4-(dimethylamino)phenyl]-1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-1-[(1,3,5-trimethyl-4-pyrazolyl)methyl]thioureaPlasmodium falciparum 3D7Potency28.183810
N-(1,3-benzodioxol-5-yl)-4-(4-methyl-1-piperidinyl)-3-nitrobenzamidePlasmodium falciparum 3D7Potency10.000010
(4-chloro-1-ethyl-3-pyrazolyl)-[3-(2-hydroxyphenyl)-5-(2-naphthalenyl)-3,4-dihydropyrazol-2-yl]methanonePlasmodium falciparum 3D7Potency3.162310
5-[2-furanyl-[4-(phenylmethyl)-1-piperidinyl]methyl]-6-thiazolo[3,2-b][1,2,4]triazololPlasmodium falciparum 3D7Potency31.622810
1-butyl-3-[[oxo-(5-propan-2-yl-3-thiophenyl)methyl]amino]thioureaPlasmodium falciparum 3D7Potency0.335910
N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-4-(1-pyrrolidinylsulfonyl)benzamidePlasmodium falciparum 3D7Potency3.981110
4-(dimethylsulfamoyl)-N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency3.548110
4-[1-(2,4-dichlorophenyl)-2-nitroethyl]-5-(2-hydroxyphenyl)-1,2-dihydropyrazol-3-onePlasmodium falciparum 3D7Potency10.000010
3-[4-(dimethylamino)phenyl]-N-methyl-5-(4-methylphenyl)-3,4-dihydropyrazole-2-carbothioamidePlasmodium falciparum 3D7Potency28.183810
4-[2-[[2-[(5-methyl-1H-pyrazol-3-yl)amino]-2-oxoethyl]thio]-4-oxo-3-quinazolinyl]-N-(phenylmethyl)butanamidePlasmodium falciparum 3D7Potency13.371410
2,5-dichloro-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamidePlasmodium falciparum 3D7Potency1.995310
2-[4-(4-chloro-2-nitrophenyl)-1-piperazinyl]phenolPlasmodium falciparum 3D7Potency22.387210
3,7-dibutyl-3,7-dimethyl-2,6-dihydro-[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dithionePlasmodium falciparum 3D7Potency22.387210
6-chloro-2-[(1H-1,2,4-triazol-5-ylthio)methyl]imidazo[1,2-a]pyridinePlasmodium falciparum 3D7Potency12.589310
[5-[(3,5-dimethyl-4-nitro-1-pyrazolyl)methyl]-2-furanyl]-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]methanonePlasmodium falciparum 3D7Potency7.079510
(3,5-dichloroanilino)thioureaPlasmodium falciparum 3D7Potency3.548110
sib 1757Plasmodium falciparum 3D7Potency14.125410
2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamidePlasmodium falciparum 3D7Potency22.387210
fraxetinPlasmodium falciparum 3D7Potency3.548110
sphingosinePlasmodium falciparum 3D7Potency11.220210
apigeninPlasmodium falciparum 3D7Potency35.481310
luteolin-7-glucosidePlasmodium falciparum 3D7Potency1.412510
quercetin 3-o-methyl etherPlasmodium falciparum 3D7Potency5.623410
kaempferolPlasmodium falciparum 3D7Potency25.118910
rescinnaminePlasmodium falciparum 3D7Potency8.912510
esculetinPlasmodium falciparum 3D7Potency17.782810
amentoflavonePlasmodium falciparum 3D7Potency35.481310
galanginPlasmodium falciparum 3D7Potency12.589310
myricetinPlasmodium falciparum 3D7Potency0.891310
acteosidePlasmodium falciparum 3D7Potency0.794310
ellagic acidPlasmodium falciparum 3D7Potency0.794310
astragalinPlasmodium falciparum 3D7Potency3.162310
domoic acidPlasmodium falciparum 3D7Potency28.183810
4-hydroxyestradiolPlasmodium falciparum 3D7Potency25.118910
indocyanine greenPlasmodium falciparum 3D7Potency8.912510
3-ethyl-2-sulfanylidene-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-onePlasmodium falciparum 3D7Potency4.466810
1-acetyl-N-[3-(N-ethyl-3-methylanilino)propyl]-2,3-dihydroindole-5-sulfonamidePlasmodium falciparum 3D7Potency39.810710
N-(5-bromo-2-thiazolyl)-3-phenyl-2-(1-pyrrolyl)propanamidePlasmodium falciparum 3D7Potency35.481310
4-[5-(4-methoxyphenyl)-3-isoxazolyl]-N-(2-pyridinylmethyl)butanamidePlasmodium falciparum 3D7Potency22.387210
4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency17.782810
2-(1,3-benzodioxol-5-ylmethyl)-3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-3H-isoindol-1-onePlasmodium falciparum 3D7Potency28.183810
N-[2-(4-morpholinyl)ethyl]-4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazine-6-carboxamidePlasmodium falciparum 3D7Potency10.000010
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrilePlasmodium falciparum 3D7Potency35.481310
N-[(3-methyl-6-imidazo[2,1-b]thiazolyl)methyl]-1-propanesulfonamidePlasmodium falciparum 3D7Potency22.387210
ro 41-1049Plasmodium falciparum 3D7Potency22.387210
u-44619Plasmodium falciparum 3D7Potency3.548110
IsolicoflavonolPlasmodium falciparum 3D7Potency19.952610
salazinic acidPlasmodium falciparum 3D7Potency1.122010
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acidPlasmodium falciparum 3D7Potency28.183810
3,5-dimethoxycinnamic acidPlasmodium falciparum 3D7Potency39.810710
erbstatinPlasmodium falciparum 3D7Potency14.125410
ag 538Plasmodium falciparum 3D7Potency1.584910
ag-490Plasmodium falciparum 3D7Potency22.387210
2-pyridylcarboxaldehyde benzoylhydrazonePlasmodium falciparum 3D7Potency2.511910
alpha-benzoin oximePlasmodium falciparum 3D7Potency15.848910
7,8-dihydroxy-4-methylcoumarinPlasmodium falciparum 3D7Potency15.848910
flavokawain bPlasmodium falciparum 3D7Potency14.125410
styrylquinolinePlasmodium falciparum 3D7Potency39.810710
4-amino-6,7-diphenyl-3H-pteridine-2-thionePlasmodium falciparum 3D7Potency2.511910
6-bromo-5-methyl-1,3-dihydroimidazo[4,5-b]pyridine-2-thionePlasmodium falciparum 3D7Potency2.818410
1-methyl-beta-carboline-3-carboxylic acidPlasmodium falciparum 3D7Potency0.794310
trientine hydrochloridePlasmodium falciparum 3D7Potency0.891310
(2R)-2-[[(2R,3R,4R)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-2-[(2S,3R,4S,5S)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]acetic acidPlasmodium falciparum 3D7Potency4.466810
aurantiaminePlasmodium falciparum 3D7Potency19.952610
2-pyridylcarboxaldehyde isonicotinoylhydrazonePlasmodium falciparum 3D7Potency1.122010
3-(4-fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene 1-oxidePlasmodium falciparum 3D7Potency31.622810
famotidinePlasmodium falciparum 3D7Potency15.848910
3,3'-diethylthiatricarbocyanine iodide, 3h-labeledPlasmodium falciparum 3D7Potency25.118910
quinaldine redPlasmodium falciparum 3D7Potency14.125410
5-(4-methyl-1-naphthalenyl)-N-phenyl-2-furancarboxamidePlasmodium falciparum 3D7Potency31.622810
3,3'-diethylthiacarbocyanine iodidePlasmodium falciparum 3D7Potency39.810710
chloride of pseudoisocyaninePlasmodium falciparum 3D7Potency22.387210
2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-N-(3-methylphenyl)acetamidePlasmodium falciparum 3D7Potency17.782810
N3,N6-bis(2,5-dimethoxyphenyl)pyridazine-3,6-diaminePlasmodium falciparum 3D7Potency22.387210
N'1-(6-methylpyridazin-3-yl)-4-chlorobenzene-1-carbohydrazidePlasmodium falciparum 3D7Potency1.412510
3-(2-oxolanylmethylthio)-5,6-diphenyl-1,2,4-triazinePlasmodium falciparum 3D7Potency22.387210
salsolinol hydrobromidePlasmodium falciparum 3D7Potency1.778310
1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-6-yl]hexitolPlasmodium falciparum 3D7Potency3.981110
paroxetine maleatePlasmodium falciparum 3D7Potency33.997210
sclerotiorinPlasmodium falciparum 3D7Potency19.952610
4-hydroxyderricinPlasmodium falciparum 3D7Potency39.810710
fomenePlasmodium falciparum 3D7Potency35.481310
2-(1,3-benzoxazol-2-ylamino)-7,7-dimethyl-4-(2-pyridinyl)-1,4,6,8-tetrahydroquinazolin-5-onePlasmodium falciparum 3D7Potency0.707910
cefpodoxime proxetilPlasmodium falciparum 3D7Potency11.220210
3,4,5-trimethoxy-N-[[[oxo-[(1S,2S)-2-phenylcyclopropyl]methyl]hydrazo]-sulfanylidenemethyl]benzamidePlasmodium falciparum 3D7Potency25.118910
b 43Plasmodium falciparum 3D7Potency15.848910
[4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazin-6-yl]-(1-piperidinyl)methanonePlasmodium falciparum 3D7Potency35.481310
(4R)-4-[[(2S)-2-[[[2-(1-amino-2-methylbutyl)-4,5-dihydrothiazol-4-yl]-oxomethyl]amino]-4-methyl-1-oxopentyl]amino]-5-[[(2S,3S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5Plasmodium falciparum 3D7Potency10.000010
epinephrine bitartratePlasmodium falciparum 3D7Potency39.810710
3-nitrobenzaldehyde isonicotinoylhydrazonePlasmodium falciparum 3D7Potency19.952610
N-(3-methylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamidePlasmodium falciparum 3D7Potency4.466810
N'-(4-fluoro-1,3-benzothiazol-2-yl)-2-phenoxyacetohydrazidePlasmodium falciparum 3D7Potency1.412510
N'-(4,5-dimethyl-1,3-benzothiazol-2-yl)propanehydrazidePlasmodium falciparum 3D7Potency1.778310
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)propanehydrazidePlasmodium falciparum 3D7Potency11.220210
N-(6-fluoro-1,3-benzothiazol-2-yl)-6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-aminePlasmodium falciparum 3D7Potency2.238710
3-(3-methylphenyl)-2-sulfanylidene-1H-benzofuro[3,2-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency3.548110
N-(4-acetylphenyl)-2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]acetamidePlasmodium falciparum 3D7Potency17.782810
N'-(1-methyl-4-pyrazolo[3,4-d]pyrimidinyl)-2-(1-naphthalenyl)acetohydrazidePlasmodium falciparum 3D7Potency7.943310
(3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dionePlasmodium falciparum 3D7Potency39.810710
1-(3-ethylphenyl)-3-(1-naphthalenyl)thioureaPlasmodium falciparum 3D7Potency25.118910
3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dionePlasmodium falciparum 3D7Potency17.782810
3-hydroxy-2-methyl-1-(phenylmethyl)-4-pyridinonePlasmodium falciparum 3D7Potency10.000010
3-(4-ethoxyphenyl)-1-[3-(4-morpholinyl)propyl]-1-[(1-propyl-3,4-dihydro-2H-quinolin-6-yl)methyl]ureaPlasmodium falciparum 3D7Potency26.679510
1-[(2-chlorophenyl)methyl]-N-[3-(N-ethyl-3-methylanilino)propyl]-5-oxo-2-pyrrolidinecarboxamidePlasmodium falciparum 3D7Potency8.912510
N-(1,3-benzodioxol-5-yl)-2-(4-methylphenyl)-3-imidazo[1,2-a]pyrazinaminePlasmodium falciparum 3D7Potency28.183810
hydralazine 4-anisaldehyde hydrazonePlasmodium falciparum 3D7Potency0.707910
cid-2745687Plasmodium falciparum 3D7Potency2.818410
naloxone benzoylhydrazonePlasmodium falciparum 3D7Potency28.183810
1-(2-methoxyphenyl)piperazine hydrochloridePlasmodium falciparum 3D7Potency3.981110
lissamine rhodamine bPlasmodium falciparum 3D7Potency14.125410
garcinone ePlasmodium falciparum 3D7Potency28.183810
macelignanPlasmodium falciparum 3D7Potency22.387210
cefotaxime sodiumPlasmodium falciparum 3D7Potency3.162310
pyrenophorolPlasmodium falciparum 3D7Potency39.810710
[5-hydroxy-3-(4-methoxyphenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]-thiophen-2-ylmethanonePlasmodium falciparum 3D7Potency14.125410
GR 127935 hydrochloridePlasmodium falciparum 3D7Potency31.622810
5-amino-1-(4-methylphenylsulfonyl)-4-pyrazolin-3-onePlasmodium falciparum 3D7Potency31.622810
2-(4-butan-2-ylanilino)-3-pyridinecarbonitrilePlasmodium falciparum 3D7Potency28.183810
N-(2-methoxyethyl)-2-[[3-[(4-methoxyphenyl)methyl]-6-(4-morpholinyl)-4-oxo-2-quinazolinyl]thio]acetamidePlasmodium falciparum 3D7Potency10.000010
2-(2,1,3-benzothiadiazol-4-ylsulfonylamino)-N-(6-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamidePlasmodium falciparum 3D7Potency11.220210
R-(-)-actinodaphninePlasmodium falciparum 3D7Potency28.183810
6-fluoronorepinephrine monohydrochloride, (+-)-isomerPlasmodium falciparum 3D7Potency1.122010
calcimycinPlasmodium falciparum 3D7Potency3.981110
2-hydroxyapomorphine, (r)-isomerPlasmodium falciparum 3D7Potency10.000010
N-[5-[2-(5-chloro-2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]hexanamidePlasmodium falciparum 3D7Potency39.810710
N-[5-[2-(3-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-3-methylbutanamidePlasmodium falciparum 3D7Potency17.782810
1-(4-bromophenyl)-3-[[[4-(4-morpholinyl)-3-nitrophenyl]-oxomethyl]amino]thioureaPlasmodium falciparum 3D7Potency0.707910
3-(3-chlorophenyl)-1-[(1-methyl-3-indolyl)methyl]-1-[3-(4-morpholinyl)propyl]thioureaPlasmodium falciparum 3D7Potency19.952610
N-butyl-N-methyl-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamidePlasmodium falciparum 3D7Potency17.782810
2-[2-fluoro-5-(4-methyl-1-piperazinyl)-4-nitrophenyl]-3,4-dihydro-1H-isoquinolinePlasmodium falciparum 3D7Potency11.220210
4-[3-(3-fluorophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamidePlasmodium falciparum 3D7Potency14.125410
3-[(3-methylphenyl)methylthio]-6-thiophen-2-ylpyridazinePlasmodium falciparum 3D7Potency17.782810
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl 6-O-(6-deoxyhexopyranosyl)hexopyranosidePlasmodium falciparum 3D7Potency7.943310
[5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoatePlasmodium falciparum 3D7Potency35.481310
(R)-Bitalin APlasmodium falciparum 3D7Potency39.810710
(1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-2-oxido-3,4-dihydro-1H-isoquinolin-2-ium-7-olPlasmodium falciparum 3D7Potency8.912510
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl 2-O-hexopyranosylhexopyranosidePlasmodium falciparum 3D7Potency7.079510
4-[3-(4-methylphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamidePlasmodium falciparum 3D7Potency11.220210
desmethylenylnocardaminePlasmodium falciparum 3D7Potency7.943310
rabeprazole sodiumPlasmodium falciparum 3D7Potency17.782810
win 62577Plasmodium falciparum 3D7Potency19.952610
3-[(4-methoxyphenyl)methyl]-N-(3-methoxypropyl)-2,4-dioxo-1H-quinazoline-7-carboxamidePlasmodium falciparum 3D7Potency35.481310
3-(2,4-dimethoxyphenyl)-N-(3-fluoro-4-methylphenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamidePlasmodium falciparum 3D7Potency3.162310
2-[1-(4-bromophenoxy)butyl]-8,9-dimethoxy-3H-[1,2,4]triazolo[1,5-c]quinazoline-5-thionePlasmodium falciparum 3D7Potency2.238710
N-[3-(diethylamino)propyl]-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamidePlasmodium falciparum 3D7Potency35.481310
5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamidePlasmodium falciparum 3D7Potency15.848910
5-chloro-2-[(3-methylphenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamidePlasmodium falciparum 3D7Potency17.782810
1-[(1-ethyl-3,4-dihydro-2H-quinolin-6-yl)methyl]-3-(3-methylphenyl)-1-[2-(4-morpholinyl)ethyl]thioureaPlasmodium falciparum 3D7Potency14.125410
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamidePlasmodium falciparum 3D7Potency3.548110
5-methyl-5-pentyl-2-phenyl-1,2,4-triazolidine-3-thionePlasmodium falciparum 3D7Potency7.943310
dafadine BPlasmodium falciparum 3D7Potency3.162310
(6-methoxy-2-naphthalenyl)-[1-[(2-methyl-5-thiazolyl)methyl]-3-piperidinyl]methanonePlasmodium falciparum 3D7Potency17.782810
[1-[(6-chloro-2H-1-benzopyran-3-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinyl]methanolPlasmodium falciparum 3D7Potency0.631010
1-cyclohexyl-2-(1H-imidazol-2-ylmethyl)-1,3,4,9-tetrahydropyrido[3,4-b]indolePlasmodium falciparum 3D7Potency14.125410
[1-(2-benzofuranylmethyl)-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanolPlasmodium falciparum 3D7Potency19.952610
1-(1,5-dimethyl-3-pyrazolyl)-N-[[5-(2-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl]methanaminePlasmodium falciparum 3D7Potency28.183810
2-[[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-(2-oxolanylmethyl)acetamidePlasmodium falciparum 3D7Potency39.810710
N'-[1-(3,4-dimethylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]acetohydrazidePlasmodium falciparum 3D7Potency1.258910
2-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(3-ethylphenyl)-3-hydroxy-5-nitro-4-triazoliminePlasmodium falciparum 3D7Potency14.125410
4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]piperidinePlasmodium falciparum 3D7Potency28.183810
N-(5-chloro-2-pyridinyl)-4H-thieno[3,2-c][1]benzopyran-2-carboxamidePlasmodium falciparum 3D7Potency5.011910
1-[3-[(2R,4R)-2-[[4-(hydroxymethyl)phenyl]methoxy]-6-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]-3,4-dihydro-2H-pyran-4-yl]-1-indolyl]ethanonePlasmodium falciparum 3D7Potency39.810710
(2S)-4-methyl-2-[[oxo-[5-[oxo-[(phenylmethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]pentanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency7.079510
(2S)-2-[[[5-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]propanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency17.782810
(2S)-2-[[oxo-[5-[oxo-[(phenylmethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]-3-phenylpropanoic acid (phenylmethyl) esterPlasmodium falciparum 3D7Potency3.162310
(2S)-4-methyl-2-[[oxo-[5-[oxo-[(phenylmethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]pentanoic acid (phenylmethyl) esterPlasmodium falciparum 3D7Potency2.818410
(2S)-4-methyl-2-[[[5-(methylcarbamoyl)-1H-imidazol-4-yl]-oxomethyl]amino]pentanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency12.589310
(2S)-4-methyl-2-[[[5-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]pentanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency14.125410
(2S)-2-[[[5-[[methyl-(phenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency31.622810
violaceol IIPlasmodium falciparum 3D7Potency4.466810
(2R,4R)-N-(1H-benzimidazol-2-ylmethyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyran-6-carboxamidePlasmodium falciparum 3D7Potency28.183810
5-chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(phenylmethyl)sulfonyl-4-pyrimidinecarboxamidePlasmodium falciparum 3D7Potency39.810710
5-chloro-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-[(4-fluorophenyl)methylsulfonyl]-4-pyrimidinecarboxamidePlasmodium falciparum 3D7Potency35.481310
xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-GlucopyranosidePlasmodium falciparum 3D7Potency1.258910
thimerosalPlasmodium falciparum 3D7Potency14.125410
(3S,5R,6S,7E,9x)-7-Megastigmene-3,6,9-triol 9-glucosidePlasmodium falciparum 3D7Potency11.220210
2-amino-N-[3-methoxy-5-[oxo-[3-(trifluoromethyl)anilino]methyl]phenyl]-4-thiazolecarboxamidePlasmodium falciparum 3D7Potency22.387210
8-{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl}-5,7-dimethoxy-4-pentyl-2H-chromen-2-onePlasmodium falciparum 3D7Potency8.912510
3-(1,3-benzodioxol-5-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanonePlasmodium falciparum 3D7Potency39.810710
8-[1-[4-(dimethylamino)phenyl]-3-(3-methyl-1-piperidinyl)propyl]-5,7-dimethoxy-4-phenyl-1-benzopyran-2-onePlasmodium falciparum 3D7Potency15.848910
(3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-onePlasmodium falciparum 3D7Potency15.848910
4-[[[5-[[[(2S)-1-[(2-methylpropan-2-yl)oxy]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-1-oxohexan-2-yl]amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]benzoic acid ethyl esterPlasmodium falciparum 3D7Potency5.623410
2-[[[4-[(3-methylanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid (phenylmethyl) esterPlasmodium falciparum 3D7Potency1.584910
N4-(4-methoxyphenyl)-N5-[(1S)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamidePlasmodium falciparum 3D7Potency3.548110
(2S)-2-[[[4-[(3-methylanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-3-phenylpropanoic acid (phenylmethyl) esterPlasmodium falciparum 3D7Potency7.943310
2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl esterPlasmodium falciparum 3D7Potency1.778310
(2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency1.995310
(2S)-2-[[[4-[[4-[[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]methyl]anilino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]propanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency7.079510
N4-(4-methoxyphenyl)-N5-[(1R)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamidePlasmodium falciparum 3D7Potency3.548110
1-[1-(4-butan-2-ylphenyl)ethyl]-3-[(4-fluorophenyl)methyl]thioureaPlasmodium falciparum 3D7Potency31.622810
N'-[(2-methoxyphenyl)-oxomethyl]-2-(4-morpholinyl)-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency10.000010
amorfrutin aPlasmodium falciparum 3D7Potency39.810710
N-[[3-(4-nitrophenyl)sulfonyl-2-oxazolidinyl]methyl]-N'-(2-pyridinylmethyl)oxamidePlasmodium falciparum 3D7Potency10.000010
1-[(4-fluorophenyl)methyl]-3-[1-(4-propan-2-ylphenyl)propyl]thioureaPlasmodium falciparum 3D7Potency25.118910
cefotiam hydrochloridePlasmodium falciparum 3D7Potency3.548110
3-[1-[[1-(4-methoxyphenyl)cyclopropyl]-oxomethyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-onePlasmodium falciparum 3D7Potency1.584910
ampicillin sodiumPlasmodium falciparum 3D7Potency3.548110
cefmetazole sodiumPlasmodium falciparum 3D7Potency10.000010
cefoxitin sodiumPlasmodium falciparum 3D7Potency35.481310
methicillin sodiumPlasmodium falciparum 3D7Potency14.125410
canrenoate potassiumPlasmodium falciparum 3D7Potency22.387210
cefamandole nafatePlasmodium falciparum 3D7Potency10.000010
cefazolin sodiumPlasmodium falciparum 3D7Potency5.011910
acid blue 129Plasmodium falciparum 3D7Potency28.183810
dicloxacillin sodiumPlasmodium falciparum 3D7Potency3.162310
leu-ser-glu-ala-leuPlasmodium falciparum 3D7Potency4.466810
N-[5-Bromo-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloridePlasmodium falciparum 3D7Potency35.481310
N-[5-Fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloridePlasmodium falciparum 3D7Potency28.183810
(2S)-2-[[oxo-[5-[oxo-(4-phenyl-1-piperazinyl)methyl]-1H-imidazol-4-yl]methyl]amino]-3-phenylpropanoic acid tert-butyl esterPlasmodium falciparum 3D7Potency11.220210
2-[[[4-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl esterPlasmodium falciparum 3D7Potency3.548110
(2R)-N2-[2-(4-bicyclo[2.2.1]heptanyl)ethyl]-N1-[(2R,3R)-3-methyl-1-(methylamino)pentan-2-yl]hexane-1,2-diaminePlasmodium falciparum 3D7Potency11.220210
4-[(2S)-2-[2-(4-ethoxyphenyl)ethylamino]-3-[[(2S)-1-(methylamino)hexan-2-yl]amino]propyl]phenolPlasmodium falciparum 3D7Potency4.466810
(2R)-3-[[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]amino]-2-[(1-phenylcyclopropyl)methylamino]-1-propanolPlasmodium falciparum 3D7Potency3.548110
(2R)-3-[[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]amino]-2-[2-[3-(trifluoromethyl)phenyl]ethylamino]-1-propanolPlasmodium falciparum 3D7Potency3.981110
2-[[[4-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl esterPlasmodium falciparum 3D7Potency14.125410
3-(4-Amino-3,5-dichlorobenzoyl)-2-(3-amino-3-oxopropyl)-2H-indazole 1-oxidePlasmodium falciparum 3D7Potency5.011910
norepinephrine bitartratePlasmodium falciparum 3D7Potency2.818410
2-(4-morpholinyl)-N'-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency10.000010
N'-[(2-methyl-3-nitrophenyl)-oxomethyl]-2-(4-morpholinyl)-4-thiazolecarbohydrazidePlasmodium falciparum 3D7Potency10.000010
pd 120697Plasmodium falciparum 3D7Potency3.981110
4-chloro-N-(5-methyl-1,3,4-oxadiazol-2-yl)-5-dithiazoliminePlasmodium falciparum 3D7Potency19.952610
4-[3-(3-methylphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamidePlasmodium falciparum 3D7Potency15.848910
4-[3-(3-bromophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamidePlasmodium falciparum 3D7Potency5.011910
flavoskyrinPlasmodium falciparum 3D7Potency5.011910
N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4,4,4-trifluorobutanamidePlasmodium falciparum 3D7Potency4.466810
1-[[(2S,3S)-10-[[(cyclohexylamino)-oxomethyl]amino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methyl-3-[4-(trifluoromethyl)phenyl]ureaPlasmodium falciparum 3D7Potency2.238710
N-[(2S,3S)-2-[[benzenesulfonyl(methyl)amino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamidePlasmodium falciparum 3D7Potency6.309610
2-[5-[(3,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridinePlasmodium falciparum 3D7Potency5.011910
amz 30Plasmodium falciparum 3D7Potency31.622810
oxytetracycline, anhydrousPlasmodium falciparum 3D7Potency1.000010
1-butyl-4-hydroxy-N-(3-methyl-2-pyridinyl)-2-oxo-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency3.548110
4-hydroxy-1-(2-methylpropyl)-2-oxo-N-(2-sulfamoylphenyl)-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency26.679510
N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-1-prop-2-enyl-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency8.912510
4-hydroxy-1-methyl-2-oxo-N-(4-oxo-2-propyl-3-quinazolinyl)-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency39.810710
1-butyl-N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency3.981110
N'-[(2-chlorophenyl)-oxomethyl]-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarbohydrazidePlasmodium falciparum 3D7Potency3.548110
4-hydroxy-1-methyl-N'-[(3-methylphenyl)-oxomethyl]-2-oxo-3-quinolinecarbohydrazidePlasmodium falciparum 3D7Potency25.118910
LSM-23565Plasmodium falciparum 3D7Potency15.848910
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxoheptyl)-3-quinolinecarbohydrazidePlasmodium falciparum 3D7Potency1.122010
N-(2-aminophenyl)-4-hydroxy-2-oxo-1-pentyl-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency14.125410
methacycline monohydrochloridePlasmodium falciparum 3D7Potency3.162310
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxodecyl)-3-quinolinecarbohydrazidePlasmodium falciparum 3D7Potency3.548110
LSM-31922Plasmodium falciparum 3D7Potency1.995310
4-hydroxy-N-(2-methyl-4-oxo-3-quinazolinyl)-1-(2-methylpropyl)-2-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamidePlasmodium falciparum 3D7Potency2.667910
4-hydroxy-1-(2-methylpropyl)-2-oxo-N-[4-oxo-2-(phenylmethyl)-3-quinazolinyl]-5,6,7,8-tetrahydroquinoline-3-carboxamidePlasmodium falciparum 3D7Potency1.778310
a 1062Plasmodium falciparum 3D7Potency3.162310
N-[2-(4-chlorophenyl)ethyl]-4-hydroxy-2-oxo-1-propyl-3-quinolinecarboxamidePlasmodium falciparum 3D7Potency6.309610
3-cinnamoyl-4-hydroxy-6-methyl-2h-pyran-2-onePlasmodium falciparum 3D7Potency35.481310
6-[5-[[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]methyl]-2-oxo-1,3-dihydroimidazol-4-yl]-6-oxohexanoic acid ethyl esterPlasmodium falciparum 3D7Potency21.192310
tju 103Plasmodium falciparum 3D7Potency25.118910
hemateinPlasmodium falciparum 3D7Potency2.818410
1-hydroxyphenazinePlasmodium falciparum 3D7Potency10.000010
2-[(2-methyl-2,3-dihydroindol-1-yl)methyl]-4-oxo-1H-quinazoline-7-carboxylic acid methyl esterPlasmodium falciparum 3D7Potency35.481310
MMP-9-IN-1Plasmodium falciparum 3D7Potency15.848910
N-(1,3-benzodioxol-5-yl)-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamidePlasmodium falciparum 3D7Potency1.000010
6,8-dibromo-2-[[[4-(difluoromethoxy)phenyl]methyl-methylamino]methyl]-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency7.079510
oosporeinPlasmodium falciparum 3D7Potency0.562310
lomofunginPlasmodium falciparum 3D7Potency1.258910
5-(4-methoxyphenyl)-6-sulfanylidene-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-onePlasmodium falciparum 3D7Potency10.000010
1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency39.810710
N-[4-[2-(2-methoxyethylamino)-6H-1,3,4-thiadiazin-5-yl]phenyl]acetamidePlasmodium falciparum 3D7Potency35.481310
pyridoxal 4-methoxybenzoyl hydrazonePlasmodium falciparum 3D7Potency25.118910
N-butyl-5-(3,4-dimethylphenyl)-6H-1,3,4-thiadiazin-2-aminePlasmodium falciparum 3D7Potency22.387210
5-[1-[(2-chlorophenyl)methyl]-2,5-dimethyl-3-pyrrolyl]-N-(1-methoxypropan-2-yl)-6H-1,3,4-thiadiazin-2-aminePlasmodium falciparum 3D7Potency19.952610
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-[4-(4-morpholinyl)phenyl]acetamidePlasmodium falciparum 3D7Potency44.668410
1-[4-[[(5-methyl-7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)-oxomethyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl esterPlasmodium falciparum 3D7Potency37.685810
2-[(dimethylamino)methyl]-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]onePlasmodium falciparum 3D7Potency2.377810
2-(diethylaminomethyl)-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]onePlasmodium falciparum 3D7Potency0.751910
6,7-dimethoxy-2-[[methyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]methyl]-1H-quinazolin-4-onePlasmodium falciparum 3D7Potency2.667910
galloflavinPlasmodium falciparum 3D7Potency10.000010
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-[2-(methylthio)phenyl]acetamidePlasmodium falciparum 3D7Potency1.995310
5,5-diethyl-2-hydrazinyl-1,6-dihydrobenzo[h]quinazolin-4-onePlasmodium falciparum 3D7Potency19.952610
N-[4-[2-(2-oxolanylmethylamino)-6H-1,3,4-thiadiazin-5-yl]phenyl]acetamidePlasmodium falciparum 3D7Potency1.412510
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-(3-fluorophenyl)acetamidePlasmodium falciparum 3D7Potency0.316210
N-[2-(4-chlorophenyl)ethyl]-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamidePlasmodium falciparum 3D7Potency8.912510
5-(2,5-difluorophenyl)-N-(2-oxolanylmethyl)-6H-1,3,4-thiadiazin-2-aminePlasmodium falciparum 3D7Potency5.623410
N-[(cyclohexylamino)-oxomethyl]-2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]acetamidePlasmodium falciparum 3D7Potency1.258910
7-[[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]methyl]-5-thiazolo[3,2-a]pyrimidinonePlasmodium falciparum 3D7Potency1.000010
2-(butylthio)-4-oxo-1H-pyrimidine-6-carboxylic acidPlasmodium falciparum 3D7Potency39.810710
4-[[(4-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)thio]methyl]benzoic acidPlasmodium falciparum 3D7Potency7.079510