Proteins > Sodium channel protein type 1 subunit alpha
Page last updated: 2024-08-07 15:38:12

Sodium channel protein type 1 subunit alpha

A sodium channel protein type 1 subunit alpha that is encoded in the genome of rat. [OMA:P04774, PRO:DNx]

Synonyms

Sodium channel protein brain I subunit alpha;
Sodium channel protein type I subunit alpha;
Voltage-gated sodium channel subunit alpha Nav1.1

Research

Bioassay Publications (9)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's6 (66.67)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Compounds (20)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
ebselenRattus norvegicus (Norway rat)Potency5.798810
1,6-bismaleimidohexaneRattus norvegicus (Norway rat)Potency6.506410
Adenosine 5'-monophosphate monohydrateRattus norvegicus (Norway rat)Potency6.506410

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
carbamazepineRattus norvegicus (Norway rat)IC50167.000012
racemethorphanRattus norvegicus (Norway rat)IC50150.650022
fluoxetineRattus norvegicus (Norway rat)IC5013.100011
lidocaineRattus norvegicus (Norway rat)IC5056.000012
lamotrigineRattus norvegicus (Norway rat)IC5082.633323
lidoflazineRattus norvegicus (Norway rat)Ki0.077011
mexiletineRattus norvegicus (Norway rat)IC5047.000011
norfluoxetineRattus norvegicus (Norway rat)IC500.800011
sipatrigineRattus norvegicus (Norway rat)IC5017.850011
lubeluzoleRattus norvegicus (Norway rat)IC502.939011
lifarizineRattus norvegicus (Norway rat)IC500.494011
l 741742Rattus norvegicus (Norway rat)Ki1.900011
oxytocinRattus norvegicus (Norway rat)Ki0.061012
(S)-(-)-pindololRattus norvegicus (Norway rat)Ki0.110011
flunarizineRattus norvegicus (Norway rat)Ki0.053011
dextromethorphanRattus norvegicus (Norway rat)IC505.650022
tetrodotoxinRattus norvegicus (Norway rat)IC500.010010