Proteins > Transient receptor potential cation channel subfamily M member 8
Page last updated: 2024-08-07 14:59:13
Transient receptor potential cation channel subfamily M member 8
A transient receptor potential cation channel TRPM8 that is encoded in the genome of mouse. [OMA:Q8R4D5, PRO:DNx]
Synonyms
Long transient receptor potential channel 6;
LTrpC-6;
LTrpC6;
Transient receptor potential p8;
Trp-p8
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| allyl isothiocyanate | Mus musculus (house mouse) | EC50 | 0.5000 | 1 | 1 |
| voacamine | Mus musculus (house mouse) | EC50 | 8.0000 | 1 | 1 |
| voacristine | Mus musculus (house mouse) | EC50 | 27.0000 | 1 | 1 |
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.Journal of natural products, , Feb-28, Volume: 77, Issue:2, 2014
Identification of Indole Alkaloid Structural Units Important for Stimulus-Selective TRPM8 Inhibition: SAR Study of Naturally Occurring Iboga Derivatives.Journal of natural products, , Aug-22, Volume: 77, Issue:8, 2014