Condition | Indicated | Relationship Strength | Studies | Trials |
Bowel Diseases, Inflammatory [description not available] | 0 | 2.15 | 1 | 0 |
Inflammatory Bowel Diseases Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS. | 0 | 2.15 | 1 | 0 |
Innate Inflammatory Response [description not available] | 0 | 7.08 | 46 | 0 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 7.08 | 46 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 7.56 | 68 | 0 |
Age-Related Memory Disorders [description not available] | 0 | 3.33 | 5 | 0 |
Memory Disorders Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions. | 0 | 3.33 | 5 | 0 |
Inflammatory Response Syndrome, Systemic [description not available] | 0 | 2.82 | 2 | 0 |
Cerebral Infarction, Middle Cerebral Artery [description not available] | 0 | 3.58 | 7 | 0 |
Systemic Inflammatory Response Syndrome A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever | 0 | 7.82 | 2 | 0 |
Infarction, Middle Cerebral Artery NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 3.58 | 7 | 0 |
ALS - Amyotrophic Lateral Sclerosis [description not available] | 0 | 5.22 | 4 | 2 |
Amyotrophic Lateral Sclerosis A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) | 0 | 10.22 | 4 | 2 |
Recrudescence [description not available] | 0 | 17.31 | 96 | 14 |
Acute Relapsing Multiple Sclerosis [description not available] | 0 | 22.97 | 396 | 84 |
MS (Multiple Sclerosis) [description not available] | 0 | 20.5 | 365 | 22 |
Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 1 | 22.5 | 365 | 22 |
Multiple Sclerosis, Relapsing-Remitting The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914) | 1 | 24.97 | 396 | 84 |
Grippe [description not available] | 0 | 3.7 | 1 | 1 |
Influenza, Human An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia. | 0 | 3.7 | 1 | 1 |
Autoimmune Disease [description not available] | 0 | 4.77 | 6 | 0 |
Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 4.77 | 6 | 0 |
Uveitis Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed) | 0 | 7.31 | 1 | 0 |
Dementia Praecox [description not available] | 0 | 2.41 | 1 | 0 |
Delayed Effects, Prenatal Exposure [description not available] | 0 | 3.5 | 2 | 0 |
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 8.39 | 8 | 2 |
Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. | 0 | 7.41 | 1 | 0 |
2019 Novel Coronavirus Disease [description not available] | 0 | 9.17 | 39 | 0 |
Co-infection [description not available] | 0 | 3.23 | 1 | 0 |
Infection [description not available] | 0 | 19.35 | 35 | 32 |
Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. | 0 | 14.35 | 35 | 32 |
E coli Infections [description not available] | 0 | 2.69 | 2 | 0 |
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI. | 0 | 2.69 | 2 | 0 |
Urinary Tract Infections Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA. | 0 | 2.31 | 1 | 0 |
Chronic Progressive Multiple Sclerosis [description not available] | 0 | 9.3 | 15 | 3 |
Multiple Sclerosis, Chronic Progressive A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914) | 1 | 13.67 | 30 | 6 |
Acute Ischemic Stroke [description not available] | 0 | 3.98 | 3 | 0 |
Injury, Ischemia-Reperfusion [description not available] | 0 | 4.18 | 12 | 0 |
Ischemic Stroke Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin. | 1 | 10.98 | 3 | 0 |
Reperfusion Injury Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 4.18 | 12 | 0 |
Degenerative Disc Disease [description not available] | 0 | 2.31 | 1 | 0 |
Intervertebral Disc Degeneration Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates. | 0 | 7.31 | 1 | 0 |
Lung Injury, Acute [description not available] | 0 | 2.72 | 2 | 0 |
Cognitive Decline [description not available] | 0 | 8.25 | 4 | 0 |
Acute Lung Injury A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 2.72 | 2 | 0 |
Cognitive Dysfunction Diminished or impaired mental and/or intellectual function. | 0 | 3.25 | 4 | 0 |
Complications, Pregnancy [description not available] | 0 | 5.94 | 2 | 1 |
Acute Confusional Senile Dementia [description not available] | 0 | 3.81 | 8 | 0 |
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 3.81 | 8 | 0 |
Allergic Encephalomyelitis [description not available] | 0 | 11.32 | 23 | 0 |
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 2.84 | 3 | 0 |
Pneumonia Infection of the lung often accompanied by inflammation. | 0 | 2.84 | 3 | 0 |
Coronary Heart Disease [description not available] | 0 | 7.41 | 1 | 0 |
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 2.41 | 1 | 0 |
Leukemia, Lymphoblastic, Acute, T Cell [description not available] | 0 | 2.41 | 1 | 0 |
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common. | 0 | 2.41 | 1 | 0 |
Palmoplantaris Pustulosis [description not available] | 0 | 14.2 | 89 | 12 |
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 1 | 16.2 | 89 | 12 |
Lymphocytopenia [description not available] | 0 | 11.03 | 59 | 0 |
Lymphopenia Reduction in the number of lymphocytes. | 0 | 11.03 | 59 | 0 |
Graft-Versus-Host Disease [description not available] | 0 | 7.63 | 2 | 0 |
Graft vs Host Disease The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. | 0 | 2.63 | 2 | 0 |
Opportunistic Infections An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression. | 0 | 3.1 | 4 | 0 |
Infections, Staphylococcal [description not available] | 0 | 2.72 | 2 | 0 |
Bacterial Meningitides [description not available] | 0 | 2.41 | 1 | 0 |
Staphylococcal Infections Infections with bacteria of the genus STAPHYLOCOCCUS. | 0 | 2.72 | 2 | 0 |
Meningitis, Bacterial Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots. | 0 | 2.41 | 1 | 0 |
Germinoblastoma [description not available] | 0 | 2.41 | 1 | 0 |
ATLL [description not available] | 0 | 2.9 | 2 | 0 |
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 2.41 | 1 | 0 |
Leukemia-Lymphoma, Adult T-Cell Aggressive T-Cell malignancy with adult onset, caused by HUMAN T-LYMPHOTROPIC VIRUS 1. It is endemic in Japan, the Caribbean basin, Southeastern United States, Hawaii, and parts of Central and South America and sub-Saharan Africa. | 0 | 2.9 | 2 | 0 |
Adverse Drug Event [description not available] | 0 | 13.15 | 29 | 7 |
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. | 0 | 13.15 | 29 | 7 |
Degenerative Diseases, Central Nervous System [description not available] | 0 | 4.66 | 5 | 0 |
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 9.66 | 5 | 0 |
Long Sleeper Syndrome [description not available] | 0 | 2.6 | 1 | 0 |
Sleep Wake Disorders Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle. | 0 | 2.6 | 1 | 0 |
Autoimmune Chronic Hepatitis [description not available] | 0 | 2.41 | 1 | 0 |
Hepatitis, Autoimmune A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES. | 0 | 2.41 | 1 | 0 |
Leukocytopenia [description not available] | 0 | 4.87 | 6 | 0 |
Leukopenia A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 4.87 | 6 | 0 |
Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. | 0 | 3.35 | 5 | 0 |
Lymphoma, Primary Effusion A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. It is associated with HUMAN HERPESVIRUS 8, most often occurring in the setting of immunodeficiency. | 0 | 2.41 | 1 | 0 |
Local Neoplasm Recurrence [description not available] | 0 | 6.6 | 7 | 2 |
Malignant Melanoma [description not available] | 0 | 3.34 | 6 | 0 |
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 3.34 | 6 | 0 |
Atrophy Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 3.97 | 2 | 1 |
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.91 | 3 | 0 |
Central Hypothyroidism [description not available] | 0 | 2.41 | 1 | 0 |
Hypothyroidism A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction. | 0 | 2.41 | 1 | 0 |
Carcinoma, Non-Small Cell Lung [description not available] | 0 | 2.41 | 1 | 0 |
Cancer of Lung [description not available] | 0 | 2.9 | 3 | 0 |
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 2.41 | 1 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 2.9 | 3 | 0 |
ER-Negative PR-Negative HER2-Negative Breast Cancer [description not available] | 0 | 2.41 | 1 | 0 |
Triple Negative Breast Neoplasms Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN. | 0 | 2.41 | 1 | 0 |
Cervical Tuberculous Lymphadenitis [description not available] | 0 | 2.41 | 1 | 0 |
Preterm Birth [description not available] | 0 | 2.6 | 1 | 0 |
Premature Birth CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION). | 0 | 2.6 | 1 | 0 |
Encephalitis, JC Polyomavirus [description not available] | 0 | 7.51 | 23 | 0 |
Leukoencephalopathy, Progressive Multifocal An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7) | 0 | 7.51 | 23 | 0 |
Rheumatoid Arthritis [description not available] | 0 | 7.6 | 1 | 0 |
Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 1 | 4.6 | 1 | 0 |
Hypermelanosis [description not available] | 0 | 2.41 | 1 | 0 |
Hyperpigmentation Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance. | 0 | 2.41 | 1 | 0 |
Chronic Illness [description not available] | 0 | 6.15 | 10 | 3 |
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 6.15 | 10 | 3 |
Aspergillus Infection [description not available] | 0 | 2.6 | 1 | 0 |
Eye Infections, Fungal Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses. | 0 | 2.6 | 1 | 0 |
Aspergillosis Infections with fungi of the genus ASPERGILLUS. | 0 | 2.6 | 1 | 0 |
Keratitis Inflammation of the cornea. | 0 | 7.6 | 1 | 0 |
Polyarthritis [description not available] | 0 | 2.6 | 1 | 0 |
Arthritis Acute or chronic inflammation of JOINTS. | 0 | 7.6 | 1 | 0 |
EBV Infections [description not available] | 0 | 2.6 | 1 | 0 |
Epstein-Barr Virus Infections Infection with human herpesvirus 4 (HERPESVIRUS 4, HUMAN); which may facilitate the development of various lymphoproliferative disorders. These include BURKITT LYMPHOMA (African type), INFECTIOUS MONONUCLEOSIS, and oral hairy leukoplakia (LEUKOPLAKIA, HAIRY). | 0 | 2.6 | 1 | 0 |
Necrotizing Enterocolitis [description not available] | 0 | 7.6 | 1 | 0 |
Enterocolitis, Necrotizing ENTEROCOLITIS with extensive ulceration (ULCER) and NECROSIS. It is observed primarily in LOW BIRTH WEIGHT INFANT. | 0 | 2.6 | 1 | 0 |
Delayed Hypersensitivity [description not available] | 0 | 3.6 | 2 | 0 |
Ache [description not available] | 0 | 3.83 | 2 | 1 |
Gouty Arthritis [description not available] | 0 | 7.6 | 1 | 0 |
Gout Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi. | 0 | 7.6 | 1 | 0 |
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 3.83 | 2 | 1 |
Arthritis, Gouty Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular. Acute and chronic gouty arthritis are associated with accumulation of MONOSODIUM URATE in and around affected joints. | 0 | 2.6 | 1 | 0 |
Cirrhosis [description not available] | 0 | 3.42 | 6 | 0 |
Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 3.42 | 6 | 0 |
Cholera Infantum [description not available] | 0 | 9.05 | 9 | 4 |
Carcinoma, Squamous Cell of Head and Neck [description not available] | 0 | 2.55 | 2 | 0 |
Carcinoma, Epidermoid [description not available] | 0 | 2.85 | 3 | 0 |
Cancer of Head [description not available] | 0 | 2.55 | 2 | 0 |
Cancer of Mouth [description not available] | 0 | 2.6 | 1 | 0 |
Squamous Cell Carcinoma of Head and Neck The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer. | 0 | 2.55 | 2 | 0 |
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.85 | 3 | 0 |
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.55 | 2 | 0 |
Mouth Neoplasms Tumors or cancer of the MOUTH. | 0 | 2.6 | 1 | 0 |
Branch Vein Occlusion [description not available] | 0 | 2.6 | 1 | 0 |
Retinal Vein Occlusion Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES. | 0 | 2.6 | 1 | 0 |
Alopecia Cicatrisata [description not available] | 0 | 2.63 | 2 | 0 |
Alopecia Absence of hair from areas where it is normally present. | 0 | 7.63 | 2 | 0 |
Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. | 0 | 6.33 | 4 | 2 |
Autism Spectrum Disorder Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V) | 0 | 2.6 | 1 | 0 |
Autism [description not available] | 0 | 2.6 | 1 | 0 |
Autistic Disorder A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V) | 0 | 2.6 | 1 | 0 |
Fatty Liver, Nonalcoholic [description not available] | 0 | 2.82 | 2 | 0 |
Alloxan Diabetes [description not available] | 0 | 3.47 | 6 | 0 |
Diabetes Mellitus, Adult-Onset [description not available] | 0 | 2.59 | 2 | 0 |
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 2.59 | 2 | 0 |
Non-alcoholic Fatty Liver Disease Fatty liver finding without excessive ALCOHOL CONSUMPTION. | 0 | 2.82 | 2 | 0 |
Thrombopenia [description not available] | 0 | 2.6 | 1 | 0 |
Thrombocytopenia A subnormal level of BLOOD PLATELETS. | 0 | 2.6 | 1 | 0 |
Allergic Contact Dermatitis [description not available] | 0 | 5.65 | 17 | 0 |
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | 0 | 5.65 | 17 | 0 |
Periodontitis, Acute Nonsuppurative [description not available] | 0 | 2.6 | 1 | 0 |
Inflammation, Endodontic [description not available] | 0 | 2.6 | 1 | 0 |
Periapical Periodontitis Inflammation of the PERIAPICAL TISSUE. It includes general, unspecified, or acute nonsuppurative inflammation. Chronic nonsuppurative inflammation is PERIAPICAL GRANULOMA. Suppurative inflammation is PERIAPICAL ABSCESS. | 0 | 2.6 | 1 | 0 |
Pulpitis Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis. | 0 | 2.6 | 1 | 0 |
Eosinophilia, Tropical [description not available] | 0 | 3.37 | 6 | 0 |
Eosinophilia Abnormal increase of EOSINOPHILS in the blood, tissues or organs. | 0 | 3.37 | 6 | 0 |
Kidney Failure A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. | 0 | 2.6 | 1 | 0 |
Renal Insufficiency Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | 0 | 2.6 | 1 | 0 |
Apoplexy [description not available] | 0 | 5.06 | 8 | 0 |
Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 5.06 | 8 | 0 |
Itching [description not available] | 0 | 3.94 | 2 | 1 |
Cancer of Skin [description not available] | 0 | 5.04 | 8 | 1 |
Cutaneous T-Cell Lymphoma [description not available] | 0 | 9.37 | 3 | 1 |
Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. | 0 | 3.94 | 2 | 1 |
Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 5.04 | 8 | 1 |
Lymphoma, T-Cell, Cutaneous A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders. | 1 | 6.37 | 3 | 1 |
Blood Clot [description not available] | 0 | 3.01 | 2 | 0 |
Thrombosis Formation and development of a thrombus or blood clot in the blood vessel. | 0 | 3.01 | 2 | 0 |
Acute Liver Injury, Drug-Induced [description not available] | 0 | 3.65 | 8 | 0 |
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 3.65 | 8 | 0 |
Colitis Gravis [description not available] | 0 | 3.52 | 1 | 0 |
Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN. | 0 | 3.52 | 1 | 0 |
Breast Cancer [description not available] | 0 | 2.93 | 3 | 0 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 2.93 | 3 | 0 |
Shingles [description not available] | 0 | 2.82 | 2 | 0 |
Herpes Zoster An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed) | 0 | 2.82 | 2 | 0 |
Experimental Spinal Cord Ischemia [description not available] | 0 | 2.6 | 1 | 0 |
T-Cell Lymphoma [description not available] | 0 | 2.6 | 1 | 0 |
Lymphoma, T-Cell A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes. | 0 | 2.6 | 1 | 0 |
Sclerosis A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve. | 0 | 7.76 | 2 | 0 |
Becker Muscular Dystrophy [description not available] | 0 | 2.6 | 1 | 0 |
Muscular Dystrophy, Duchenne An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415) | 0 | 2.6 | 1 | 0 |
Cardio-Renal Syndrome Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY). | 0 | 2.6 | 1 | 0 |
Blood Pressure, High [description not available] | 0 | 2.6 | 1 | 0 |
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 2.6 | 1 | 0 |
Impotence [description not available] | 0 | 2.6 | 1 | 0 |
Erectile Dysfunction The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction. | 0 | 7.6 | 1 | 0 |
Aura [description not available] | 0 | 3.86 | 3 | 0 |
Absence Seizure [description not available] | 0 | 2.72 | 2 | 0 |
Absence Status [description not available] | 0 | 2.6 | 1 | 0 |
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 8.86 | 3 | 0 |
Seizures Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. | 0 | 2.72 | 2 | 0 |
Status Epilepticus A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30) | 0 | 2.6 | 1 | 0 |
Cerebral Ischemia [description not available] | 0 | 4.61 | 8 | 0 |
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 4.61 | 8 | 0 |
Inborn Errors of Metabolism [description not available] | 0 | 2.21 | 1 | 0 |
Decreased Muscle Tone [description not available] | 0 | 2.21 | 1 | 0 |
Developmental Psychomotor Disorders [description not available] | 0 | 2.21 | 1 | 0 |
Metabolism, Inborn Errors Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero. | 0 | 2.21 | 1 | 0 |
Clinically Isolated CNS Demyelinating Syndrome [description not available] | 0 | 4.76 | 6 | 0 |
Enterically-Transmitted Non-A, Non-B Hepatitis [description not available] | 0 | 2.21 | 1 | 0 |
Demyelinating Diseases Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system. | 0 | 4.76 | 6 | 0 |
Hepatitis E Acute INFLAMMATION of the LIVER in humans; caused by HEPATITIS E VIRUS, a non-enveloped single-stranded RNA virus. Similar to HEPATITIS A, its incubation period is 15-60 days and is enterically transmitted, usually by fecal-oral transmission. | 0 | 2.21 | 1 | 0 |
Anterior Optic Neuritis [description not available] | 0 | 2.66 | 2 | 0 |
Optic Neuritis Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis). | 0 | 7.66 | 2 | 0 |
Allergic Neuritis, Experimental [description not available] | 0 | 2.83 | 3 | 0 |
Bile Duct Obstruction, Intrahepatic [description not available] | 0 | 2.21 | 1 | 0 |
Cholestasis, Intrahepatic Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC). | 0 | 2.21 | 1 | 0 |
Atherogenesis [description not available] | 0 | 2.21 | 1 | 0 |
Hyperglycemia, Postprandial Abnormally high BLOOD GLUCOSE level after a meal. | 0 | 2.21 | 1 | 0 |
Hyperglycemia Abnormally high BLOOD GLUCOSE level. | 0 | 7.21 | 1 | 0 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 7.21 | 1 | 0 |
Prodromal Characteristics [description not available] | 0 | 2.21 | 1 | 0 |
Dysplastic Nevus Syndrome, Hereditary [description not available] | 0 | 2.21 | 1 | 0 |
Colorectal Cancer [description not available] | 0 | 2.61 | 2 | 0 |
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 2.61 | 2 | 0 |
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 7.59 | 2 | 0 |
Disease Exacerbation [description not available] | 0 | 15.35 | 49 | 6 |
Nerve Pain [description not available] | 0 | 2.63 | 2 | 0 |
Neuralgia Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 2.63 | 2 | 0 |
Acute Hepatic Failure [description not available] | 0 | 2.25 | 1 | 0 |
Liver Failure, Acute A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. | 0 | 2.25 | 1 | 0 |
Experimental Mammary Neoplasms [description not available] | 0 | 2.42 | 2 | 0 |
Pemphigoid [description not available] | 0 | 3.17 | 1 | 0 |
Bullous Dermatoses [description not available] | 0 | 3.17 | 1 | 0 |
Acquired Form of Epidermolysis Bullosa [description not available] | 0 | 3.78 | 3 | 0 |
Pemphigoid, Bullous A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis. | 0 | 3.17 | 1 | 0 |
Epidermolysis Bullosa Acquisita Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. Direct immunofluorescence shows IMMUNOGLOBULIN G deposited at the dermo-epidermal junction. | 0 | 3.78 | 3 | 0 |
Neutropenia A decrease in the number of NEUTROPHILS found in the blood. | 0 | 2.25 | 1 | 0 |
Dermatoses [description not available] | 0 | 4.39 | 7 | 0 |
Skin Diseases Diseases involving the DERMIS or EPIDERMIS. | 0 | 4.39 | 7 | 0 |
Cirrhosis, Liver [description not available] | 0 | 2.25 | 1 | 0 |
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 2.25 | 1 | 0 |
Deep Vein Thrombosis [description not available] | 0 | 2.85 | 3 | 0 |
Thromboembolism, Venous [description not available] | 0 | 2.25 | 1 | 0 |
Embolism, Pulmonary [description not available] | 0 | 2.25 | 1 | 0 |
Pulmonary Embolism Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS. | 0 | 7.25 | 1 | 0 |
Venous Thrombosis The formation or presence of a blood clot (THROMBUS) within a vein. | 0 | 2.85 | 3 | 0 |
Venous Thromboembolism Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream. | 0 | 7.25 | 1 | 0 |
Abdominal Migraine [description not available] | 0 | 2.25 | 1 | 0 |
Migraine Disorders A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) | 0 | 2.25 | 1 | 0 |
Colicky Pain [description not available] | 0 | 5.05 | 3 | 1 |
Abdominal Pain Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 5.05 | 3 | 1 |
Brain Disorders [description not available] | 0 | 2.25 | 1 | 0 |
Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. | 0 | 2.25 | 1 | 0 |
Uremia A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms. | 0 | 2.25 | 1 | 0 |
Lesion of Sciatic Nerve [description not available] | 0 | 2.25 | 1 | 0 |
Alcoholic Liver Diseases [description not available] | 0 | 2.66 | 2 | 0 |
Alcoholic Fatty Liver [description not available] | 0 | 2.72 | 2 | 0 |
Liver Diseases, Alcoholic Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS. | 0 | 2.66 | 2 | 0 |
Bed Sores [description not available] | 0 | 2.25 | 1 | 0 |
Pressure Ulcer An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure. | 0 | 7.25 | 1 | 0 |
Cerebral Cryptococcosis [description not available] | 0 | 2.25 | 1 | 0 |
Meningitis, Cryptococcal Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2) | 0 | 2.25 | 1 | 0 |
Hepatitis B Virus Infection [description not available] | 0 | 2.25 | 1 | 0 |
Hepatitis B INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 2.25 | 1 | 0 |
Infections, Coronavirus [description not available] | 0 | 4.55 | 7 | 0 |
Pneumonia, Viral Inflammation of the lung parenchyma that is caused by a viral infection. | 0 | 4.55 | 7 | 0 |
Coronavirus Infections Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE). | 0 | 4.55 | 7 | 0 |
Diathesis [description not available] | 0 | 2.25 | 1 | 0 |
Breathlessness [description not available] | 0 | 2.25 | 1 | 0 |
Pyrexia [description not available] | 0 | 2.25 | 1 | 0 |
Cough A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. | 0 | 2.25 | 1 | 0 |
Dyspnea Difficult or labored breathing. | 0 | 2.25 | 1 | 0 |
Fever An abnormal elevation of body temperature, usually as a result of a pathologic process. | 0 | 2.25 | 1 | 0 |
Cytokine Release Syndrome A severe immune reaction characterized by excessive release of CYTOKINES. Symptoms include DYSPNEA; FEVER; HEADACHE; HYPOTENSION; NAUSEA; RASH; TACHYCARDIA; HYPOXIA; HYPERFERRITINEMIA, and MULTIPLE ORGAN FAILURE. It is associated with viral infections, SEPSIS; AUTOIMMUNE DISEASES and a variety of factors used in IMMUNOTHERAPY. | 0 | 3.17 | 1 | 0 |
Acute Respiratory Distress Syndrome [description not available] | 0 | 3.57 | 2 | 0 |
Respiratory Distress Syndrome A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. | 0 | 3.57 | 2 | 0 |
Diabetic Angiopathies VASCULAR DISEASES that are associated with DIABETES MELLITUS. | 0 | 2.25 | 1 | 0 |
Muscular Weakness [description not available] | 0 | 2.25 | 1 | 0 |
Day Blindness [description not available] | 0 | 2.47 | 2 | 0 |
Facio-Scapulo-Humeral Dystrophy [description not available] | 0 | 2.25 | 1 | 0 |
Muscle Weakness A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251) | 0 | 2.25 | 1 | 0 |
Muscular Dystrophy, Facioscapulohumeral An autosomal dominant degenerative muscle disease characterized by slowly progressive weakness of the muscles of the face, upper-arm, and shoulder girdle. The onset of symptoms usually occurs in the first or second decade of life. Affected individuals usually present with impairment of upper extremity elevation. This tends to be followed by facial weakness, primarily involving the orbicularis oris and orbicularis oculi muscles. (Neuromuscul Disord 1997;7(1):55-62; Adams et al., Principles of Neurology, 6th ed, p1420) | 0 | 2.25 | 1 | 0 |
Cardiovascular Stroke [description not available] | 0 | 3.03 | 4 | 0 |
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 8.03 | 4 | 0 |
B16 Melanoma [description not available] | 0 | 2.51 | 2 | 0 |
Behavior Disorders [description not available] | 0 | 2.25 | 1 | 0 |
Mental Disorders Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function. | 0 | 2.25 | 1 | 0 |
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 2.25 | 1 | 0 |
Benign Paroxysmal Peritonitis [description not available] | 0 | 2.25 | 1 | 0 |
Familial Mediterranean Fever A group of HEREDITARY AUTOINFLAMMATION DISEASES, characterized by recurrent fever, abdominal pain, headache, rash, PLEURISY; and ARTHRITIS. ORCHITIS; benign MENINGITIS; and AMYLOIDOSIS may also occur. Homozygous or compound heterozygous mutations in marenostrin gene encoding PYRIN result in autosomal recessive transmission; simple heterozygous, autosomal dominant form of the disease also exists with mutations in the same gene. | 0 | 2.25 | 1 | 0 |
Allergic Reaction [description not available] | 0 | 3.02 | 4 | 0 |
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. | 0 | 3.02 | 4 | 0 |
Alopecia Circumscripta [description not available] | 0 | 4.16 | 3 | 1 |
Alopecia Areata Loss of scalp and body hair involving microscopically inflammatory patchy areas. | 0 | 9.16 | 3 | 1 |
Genetic Predisposition [description not available] | 0 | 2.58 | 2 | 0 |
Injury, Myocardial Reperfusion [description not available] | 0 | 2.5 | 2 | 0 |
Plasmodium falciparum Malaria [description not available] | 0 | 2.25 | 1 | 0 |
Cerebral Malaria [description not available] | 0 | 2.25 | 1 | 0 |
Malaria, Falciparum Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. | 0 | 2.25 | 1 | 0 |
Idiopathic Parkinson Disease [description not available] | 0 | 2.79 | 3 | 0 |
Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) | 0 | 2.79 | 3 | 0 |
Anosmia Complete or severe loss of the subjective sense of smell. Loss of smell may be caused by many factors such as a cold, allergy, OLFACTORY NERVE DISEASES, viral RESPIRATORY TRACT INFECTIONS (e.g., COVID-19), aging and various neurological disorders (e.g., ALZHEIMER DISEASE). | 0 | 2.41 | 1 | 0 |
Lassitude [description not available] | 0 | 2.41 | 1 | 0 |
Fatigue The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. | 0 | 2.41 | 1 | 0 |
Intestinal Diseases Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM. | 0 | 2.31 | 1 | 0 |
Cranial Nerve II Injuries [description not available] | 0 | 2.25 | 1 | 0 |
Friedreich Disease [description not available] | 0 | 2.89 | 3 | 0 |
Friedreich Ataxia An autosomal recessive disease, usually of childhood onset, characterized pathologically by degeneration of the spinocerebellar tracts, posterior columns, and to a lesser extent the corticospinal tracts. Clinical manifestations include GAIT ATAXIA, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary to a cardiomyopathy), and lower extremity weakness. Most forms of this condition are associated with a mutation in a gene on chromosome 9, at band q13, which codes for the mitochondrial protein frataxin. (From Adams et al., Principles of Neurology, 6th ed, p1081; N Engl J Med 1996 Oct 17;335(16):1169-75) The severity of Friedreich ataxia associated with expansion of GAA repeats in the first intron of the frataxin gene correlates with the number of trinucleotide repeats. (From Durr et al, N Engl J Med 1996 Oct 17;335(16):1169-75) | 0 | 2.89 | 3 | 0 |
Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 3.25 | 5 | 0 |
Acute Onset Vascular Dementia [description not available] | 0 | 2.31 | 1 | 0 |
Dementia, Vascular An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44) | 0 | 2.31 | 1 | 0 |
Benign Neoplasms [description not available] | 0 | 6.04 | 9 | 0 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 6.04 | 9 | 0 |
Acute Symptom Flare [description not available] | 0 | 2.31 | 1 | 0 |
Besnier-Boeck Disease [description not available] | 0 | 5.15 | 6 | 0 |
Sarcoidosis An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands. | 0 | 5.15 | 6 | 0 |
Complex Regional Pain Syndrome [description not available] | 0 | 7.31 | 1 | 0 |
Segond Fracture [description not available] | 0 | 2.31 | 1 | 0 |
Tibial Fractures Fractures of the TIBIA. | 0 | 2.31 | 1 | 0 |
Complex Regional Pain Syndromes Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33) | 0 | 2.31 | 1 | 0 |
Demyelinative Myelitis [description not available] | 0 | 2.31 | 1 | 0 |
Astrocytoma, Grade IV [description not available] | 0 | 2.78 | 3 | 0 |
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 7.78 | 3 | 0 |
Libman-Sacks Disease [description not available] | 0 | 2.31 | 1 | 0 |
Lupus Erythematosus, Systemic A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. | 0 | 2.31 | 1 | 0 |
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 2.57 | 2 | 0 |
Adjuvant Arthritis [description not available] | 0 | 2.31 | 1 | 0 |
Diffuse Large B-Cell Lymphoma [description not available] | 0 | 2.31 | 1 | 0 |
Lymphoma, Large B-Cell, Diffuse Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. | 0 | 2.31 | 1 | 0 |
Acute Kidney Failure [description not available] | 0 | 2.72 | 2 | 0 |
Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.72 | 2 | 0 |
Cardiac Remodeling, Ventricular [description not available] | 0 | 2.9 | 3 | 0 |
Abnormalities, Drug-Induced Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment. | 0 | 3.95 | 2 | 0 |
Tauopathies Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration. | 0 | 2.63 | 2 | 0 |
Amyloidosis A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits. | 0 | 7.72 | 2 | 0 |
Dysembryoma [description not available] | 0 | 2.31 | 1 | 0 |
Anti-N-Methyl-D-Aspartate Receptor Encephalitis Disorder characterized by symptoms of CATATONIA; HYPOVENTILATION; DYSKINESIAS; ENCEPHALITIS; and SEIZURES followed by a reduced CONSCIOUSNESS. It is often followed by a viral-like prodrome. Many cases are self-limiting and respond well to IMMUNOMODULATORY THERAPIES against the NMDA RECEPTORS antibodies. | 0 | 7.31 | 1 | 0 |
Teratoma A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642) | 0 | 2.31 | 1 | 0 |
Cytomegalic Inclusion Disease [description not available] | 0 | 2.31 | 1 | 0 |
Pachymeningitis [description not available] | 0 | 2.31 | 1 | 0 |
Cytomegalovirus Infections Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults. | 0 | 2.31 | 1 | 0 |
Meningitis Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6) | 0 | 7.31 | 1 | 0 |
Hypomelanosis [description not available] | 0 | 2.15 | 1 | 0 |
Vitiligo A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. | 0 | 2.5 | 2 | 0 |
Hypopigmentation A condition caused by a deficiency or a loss of melanin pigmentation in the epidermis, also known as hypomelanosis. Hypopigmentation can be localized or generalized, and may result from genetic defects, trauma, inflammation, or infections. | 0 | 2.15 | 1 | 0 |
Protein Folding Diseases [description not available] | 0 | 2.15 | 1 | 0 |
Myoclonic Jerk [description not available] | 0 | 2.15 | 1 | 0 |
Amaurosis [description not available] | 0 | 2.15 | 1 | 0 |
Infectious Myelitis [description not available] | 0 | 2.15 | 1 | 0 |
Devic Disease [description not available] | 0 | 4.34 | 6 | 0 |
Flaccid Quadriplegia [description not available] | 0 | 2.15 | 1 | 0 |
Blindness The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE. | 0 | 2.15 | 1 | 0 |
Neuromyelitis Optica A syndrome characterized by acute OPTIC NEURITIS; MYELITIS, TRANSVERSE; demyelinating and/or necrotizing lesions in the OPTIC NERVES and SPINAL CORD; and presence of specific autoantibodies to AQUAPORIN 4. | 0 | 4.34 | 6 | 0 |
Endothelioma, Vascular [description not available] | 0 | 2.15 | 1 | 0 |
Hemangioendothelioma A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866) | 0 | 2.15 | 1 | 0 |
Brain Swelling [description not available] | 0 | 3.04 | 4 | 0 |
Brain Edema Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) | 0 | 3.04 | 4 | 0 |
Brain Vascular Disorders [description not available] | 0 | 2.59 | 2 | 0 |
Cerebrovascular Disorders A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others. | 0 | 2.59 | 2 | 0 |
Sclerosis, Systemic [description not available] | 0 | 2.57 | 2 | 0 |
Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. | 0 | 2.57 | 2 | 0 |
Encephalopathy, Traumatic [description not available] | 0 | 2.57 | 2 | 0 |
Brain Injuries, Traumatic A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. | 0 | 2.57 | 2 | 0 |
HbS Disease [description not available] | 0 | 2.55 | 2 | 0 |
Di Guglielmo Disease [description not available] | 0 | 2.15 | 1 | 0 |
Anemia A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN. | 0 | 7.15 | 1 | 0 |
Anemia, Sickle Cell A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. | 0 | 2.55 | 2 | 0 |
Leukemia, Erythroblastic, Acute A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood. | 0 | 2.15 | 1 | 0 |
Blood Poisoning [description not available] | 0 | 2.58 | 2 | 0 |
Sepsis Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.58 | 2 | 0 |
Autoimmune Diabetes [description not available] | 0 | 2.58 | 2 | 0 |
Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 2.58 | 2 | 0 |
Diabetic Cardiomyopathies Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance. | 0 | 3.46 | 2 | 0 |
Cardiac Hypertrophy Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix. | 0 | 7.58 | 2 | 0 |
Kidney, Polycystic [description not available] | 0 | 2.17 | 1 | 0 |
Cardiomegaly Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES. | 0 | 2.58 | 2 | 0 |
Polycystic Kidney Diseases Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance. | 0 | 2.17 | 1 | 0 |
Proteinuria The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 2.58 | 2 | 0 |
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.72 | 3 | 0 |
Acetonemia [description not available] | 0 | 2.17 | 1 | 0 |
Brain Inflammation [description not available] | 0 | 3.1 | 4 | 0 |
Infections, Listeria [description not available] | 0 | 2.17 | 1 | 0 |
Encephalitis Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. | 0 | 8.1 | 4 | 0 |
Dermatophytoses [description not available] | 0 | 2.58 | 2 | 0 |
Tinea Fungal infection of keratinized tissues such as hair, skin and nails. The main causative fungi include MICROSPORUM; TRICHOPHYTON; and EPIDERMOPHYTON. | 0 | 2.58 | 2 | 0 |
Fungal Diseases [description not available] | 0 | 2.17 | 1 | 0 |
Mycoses Diseases caused by FUNGI. | 0 | 2.17 | 1 | 0 |
Anxiety Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. | 0 | 2.17 | 1 | 0 |
Apnea, Obstructive Sleep [description not available] | 0 | 4.48 | 1 | 1 |
Sleep Apnea, Obstructive A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395) | 1 | 6.48 | 1 | 1 |
Polyomavirus Infections Infections with POLYOMAVIRUS, which are often cultured from the urine of kidney transplant patients. Excretion of BK VIRUS is associated with ureteral strictures and CYSTITIS, and that of JC VIRUS with progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL). | 0 | 4.4 | 2 | 0 |
Fibroma, Shope [description not available] | 0 | 4.4 | 2 | 0 |
Central Retinal Edema, Cystoid [description not available] | 0 | 2.21 | 1 | 0 |
Macular Edema Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) | 0 | 2.21 | 1 | 0 |
Acquired-Immune Deficiency Syndrome Dementia Complex [description not available] | 0 | 2.17 | 1 | 0 |
HIV Coinfection [description not available] | 0 | 5.32 | 4 | 0 |
AIDS Dementia Complex A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40) | 0 | 2.17 | 1 | 0 |
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 5.32 | 4 | 0 |
Nerve Degeneration Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. | 0 | 2.17 | 1 | 0 |
Peripheral Nerve Diseases [description not available] | 0 | 2.59 | 2 | 0 |
Peripheral Nervous System Diseases Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves. | 0 | 2.59 | 2 | 0 |
Bone Marrow Diseases Diseases involving the BONE MARROW. | 0 | 2.21 | 1 | 0 |
Anasarca [description not available] | 0 | 2.58 | 2 | 0 |
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 7.58 | 2 | 0 |
Joint Pain [description not available] | 0 | 3.12 | 1 | 0 |
Arthralgia Pain in the joint. | 0 | 8.12 | 1 | 0 |
Starvation Lengthy and continuous deprivation of food. (Stedman, 25th ed) | 0 | 2.21 | 1 | 0 |
Acute Necrotizing Encephalitis, Herpetic [description not available] | 0 | 2.17 | 1 | 0 |
Encephalitis, Herpes Simplex An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4) | 0 | 2.17 | 1 | 0 |
Blood Diseases [description not available] | 0 | 2.17 | 1 | 0 |
Flushing A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress. | 0 | 11.3 | 4 | 2 |
Hematologic Diseases Disorders of the blood and blood forming tissues. | 0 | 2.17 | 1 | 0 |
Depression, Endogenous [description not available] | 0 | 2.17 | 1 | 0 |
Depressive Disorder An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. | 0 | 2.17 | 1 | 0 |
Compensatory Hyperinsulinemia A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin. | 0 | 2.17 | 1 | 0 |
Fasting Hypoglycemia HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast. | 0 | 2.17 | 1 | 0 |
Hypothermia, Accidental [description not available] | 0 | 2.17 | 1 | 0 |
Pancreatic Diseases Pathological processes of the PANCREAS. | 0 | 2.17 | 1 | 0 |
Acute Disease Disease having a short and relatively severe course. | 0 | 2.54 | 2 | 0 |
Hyperinsulinism A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS. | 0 | 2.17 | 1 | 0 |
Hypoglycemia A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. | 0 | 2.17 | 1 | 0 |
Hypothermia Lower than normal body temperature, especially in warm-blooded animals. | 0 | 2.17 | 1 | 0 |
Flatus [description not available] | 0 | 4.48 | 1 | 1 |
Flatulence Production or presence of gas in the gastrointestinal tract which may be expelled through the anus. | 0 | 4.48 | 1 | 1 |
Anoxia-Ischemia, Brain [description not available] | 0 | 2.21 | 1 | 0 |
Astrocytosis [description not available] | 0 | 2.57 | 2 | 0 |
Hypoxia-Ischemia, Brain A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions. | 0 | 2.21 | 1 | 0 |
Erythema Nodosum An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy. | 0 | 7.21 | 1 | 0 |
Nephrolithiasis Formation of stones in the KIDNEY. | 0 | 7.21 | 1 | 0 |
Anemia, Hemolytic, Acquired [description not available] | 0 | 2.48 | 2 | 0 |
Anemia, Hemolytic A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). | 0 | 2.48 | 2 | 0 |
Cirrhoses, Experimental Liver [description not available] | 0 | 2.21 | 1 | 0 |
Sterility, Female [description not available] | 0 | 2.21 | 1 | 0 |
Infertility, Female Diminished or absent ability of a female to achieve conception. | 0 | 2.21 | 1 | 0 |
Allodynia [description not available] | 0 | 2.21 | 1 | 0 |
Chronic Lymphocytic Thyroiditis [description not available] | 0 | 2.21 | 1 | 0 |
Hashimoto Disease Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM. | 0 | 2.21 | 1 | 0 |
Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis [description not available] | 0 | 2.21 | 1 | 0 |
Diffuse Mixed Small and Large Cell Lymphoma [description not available] | 0 | 2.21 | 1 | 0 |
Brachial Paresis [description not available] | 0 | 2.53 | 2 | 0 |
Lymphoma, Non-Hodgkin Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 2.21 | 1 | 0 |
Ileus A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced. | 0 | 7.25 | 1 | 0 |
Aneurysm, Anterior Cerebral Artery [description not available] | 0 | 2.25 | 1 | 0 |
Intracranial Aneurysm Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms ( | 0 | 7.25 | 1 | 0 |
Asthma, Bronchial [description not available] | 0 | 3.45 | 2 | 0 |
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 8.45 | 2 | 0 |
Legionellosis Infections with bacteria of the genus LEGIONELLA. | 0 | 2.21 | 1 | 0 |
Hyperidrosis [description not available] | 0 | 2.08 | 1 | 0 |
Foot Dermatoses Skin diseases of the foot, general or unspecified. | 0 | 4.36 | 7 | 0 |
Hyperhidrosis Excessive sweating. In the localized type, the most frequent sites are the palms, soles, axillae, inguinal folds, and the perineal area. Its chief cause is thought to be emotional. Generalized hyperhidrosis may be induced by a hot, humid environment, by fever, or by vigorous exercise. | 0 | 2.08 | 1 | 0 |
Granuloma Annulare Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures. | 0 | 6.36 | 5 | 1 |
Antibody Deficiency Syndrome [description not available] | 0 | 2.08 | 1 | 0 |
Immunologic Deficiency Syndromes Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. | 0 | 2.08 | 1 | 0 |
Kahler Disease [description not available] | 0 | 2.08 | 1 | 0 |
Multiple Myeloma A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 2.08 | 1 | 0 |
Cerebral Nocardiosis [description not available] | 0 | 2.08 | 1 | 0 |
Central Nervous System Disease [description not available] | 0 | 3 | 1 | 0 |
Central Nervous System Diseases Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord. | 0 | 3 | 1 | 0 |
Dyspareunia Recurrent genital pain occurring during, before, or after SEXUAL INTERCOURSE in either the male or the female. | 0 | 2.1 | 1 | 0 |
Lupus Erythematosus, Chronic Cutaneous [description not available] | 0 | 2.1 | 1 | 0 |
Lupus Erythematosus, Discoid A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur. | 0 | 2.1 | 1 | 0 |
Carotid Arteriopathies, Traumatic [description not available] | 0 | 2.1 | 1 | 0 |
Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 2.1 | 1 | 0 |
Coronary Restenosis Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction. | 0 | 2.1 | 1 | 0 |
Vascular Calcification Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS. | 0 | 7.1 | 1 | 0 |
Hives [description not available] | 0 | 2.98 | 4 | 0 |
Urticaria A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress. | 0 | 7.98 | 4 | 0 |
Chronic Pancreatitis [description not available] | 0 | 7.1 | 1 | 0 |
Pancreatitis, Chronic INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse. | 0 | 2.1 | 1 | 0 |
Nervous System Disorders [description not available] | 0 | 2.1 | 1 | 0 |
Nervous System Diseases Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle. | 0 | 2.1 | 1 | 0 |
Fasciitis Inflammation of the fascia. There are three major types: 1, Eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, Necrotizing fasciitis (FASCIITIS, NECROTIZING), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, Nodular/Pseudosarcomatous /Proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma. | 0 | 2.1 | 1 | 0 |
Hematologic Malignancies [description not available] | 0 | 2.1 | 1 | 0 |
Hematologic Neoplasms Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 2.1 | 1 | 0 |
Autosomal Dominant Juvenile Parkinson Disease [description not available] | 0 | 2.11 | 1 | 0 |
Parkinsonian Disorders A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA. | 0 | 2.11 | 1 | 0 |
Collagenous Colitis [description not available] | 0 | 2.1 | 1 | 0 |
Colitis, Collagenous A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show larger-than-normal band of subepithelial COLLAGEN. | 0 | 2.1 | 1 | 0 |
Acute Edematous Pancreatitis [description not available] | 0 | 2.52 | 2 | 0 |
Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 2.52 | 2 | 0 |
Acute Brain Injuries [description not available] | 0 | 2.11 | 1 | 0 |
Hemorrhage, Subarachnoid [description not available] | 0 | 2.11 | 1 | 0 |
Brain Injuries Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.11 | 1 | 0 |
Subarachnoid Hemorrhage Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status. | 0 | 2.11 | 1 | 0 |
Neurogenic Inflammation Inflammation caused by an injurious stimulus of peripheral neurons and resulting in release of neuropeptides which affect vascular permeability and help initiate proinflammatory and immune reactions at the site of injury. | 0 | 3.03 | 1 | 0 |
Experimental Neoplasms [description not available] | 0 | 2.11 | 1 | 0 |
Cancer of Colon [description not available] | 0 | 2.97 | 4 | 0 |
Colonic Neoplasms Tumors or cancer of the COLON. | 0 | 2.97 | 4 | 0 |
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.11 | 1 | 0 |
Brain Hemorrhage, Cerebral [description not available] | 0 | 2.52 | 2 | 0 |
Cerebral Hemorrhage Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 1 | 4.52 | 2 | 0 |
Colonic Inertia Symptom characterized by the passage of stool once a week or less. | 0 | 3.03 | 1 | 0 |
Constipation Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | 0 | 3.03 | 1 | 0 |
Bone Cancer [description not available] | 0 | 2.11 | 1 | 0 |
African Lymphoma [description not available] | 0 | 2.11 | 1 | 0 |
Osteogenic Sarcoma [description not available] | 0 | 2.11 | 1 | 0 |
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 2.11 | 1 | 0 |
Burkitt Lymphoma A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative. | 0 | 2.11 | 1 | 0 |
Osteosarcoma A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 2.11 | 1 | 0 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 4.47 | 8 | 0 |
Encephalitis, West Nile Fever [description not available] | 0 | 2.11 | 1 | 0 |
West Nile Fever A mosquito-borne viral illness caused by the WEST NILE VIRUS, a FLAVIVIRUS and endemic to regions of Africa, Asia, and Europe. Common clinical features include HEADACHE; FEVER; maculopapular rash; gastrointestinal symptoms; and lymphadenopathy. MENINGITIS; ENCEPHALITIS; and MYELITIS may also occur. The disease may occasionally be fatal or leave survivors with residual neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13; Lancet 1998 Sep 5;352(9130):767-71) | 0 | 2.11 | 1 | 0 |
Cardiac Toxicity [description not available] | 0 | 2.13 | 1 | 0 |
Cardiac Rupture, Traumatic [description not available] | 0 | 2.13 | 1 | 0 |
Cardiomyopathies, Primary [description not available] | 0 | 2.13 | 1 | 0 |
Cardiomyopathies A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.13 | 1 | 0 |
Cardiotoxicity Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. | 0 | 2.13 | 1 | 0 |
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. | 0 | 2.53 | 2 | 0 |
Metastase [description not available] | 0 | 2.47 | 2 | 0 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.47 | 2 | 0 |
Glomerulonephritis, Lupus [description not available] | 0 | 2.13 | 1 | 0 |
Lupus Nephritis Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). | 0 | 2.13 | 1 | 0 |
Celiac Sprue [description not available] | 0 | 2.13 | 1 | 0 |
Celiac Disease A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. | 0 | 2.13 | 1 | 0 |
Enteritis Inflammation of any segment of the SMALL INTESTINE. | 0 | 7.13 | 1 | 0 |
Gastritis Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders. | 0 | 2.13 | 1 | 0 |
Musculoskeletal Pain Discomfort stemming from muscles, LIGAMENTS, tendons, and bones. | 0 | 2.13 | 1 | 0 |
Anoxemia [description not available] | 0 | 2.15 | 1 | 0 |
Pulmonary Hypertension [description not available] | 0 | 2.15 | 1 | 0 |
Alveolitis, Fibrosing [description not available] | 0 | 2.15 | 1 | 0 |
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 2.15 | 1 | 0 |
Hypertension, Pulmonary Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES. | 0 | 2.15 | 1 | 0 |
Pulmonary Fibrosis A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death. | 0 | 2.15 | 1 | 0 |
Erythroderma, Sezary [description not available] | 0 | 2.15 | 1 | 0 |
Sezary Syndrome A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells). | 0 | 2.15 | 1 | 0 |
Carditis [description not available] | 0 | 7.04 | 1 | 0 |
Myocarditis Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies. | 0 | 7.04 | 1 | 0 |
Contact Dermatitis [description not available] | 0 | 3.76 | 10 | 0 |
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms. | 0 | 3.76 | 10 | 0 |
Licheniform Eruptions [description not available] | 0 | 2.05 | 1 | 0 |
Dermatitis Any inflammation of the skin. | 0 | 2.46 | 2 | 0 |
Dermatitis, Eczematous [description not available] | 0 | 2.46 | 2 | 0 |
Eczema A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed). | 0 | 2.46 | 2 | 0 |
Dermatitis Medicamentosa [description not available] | 0 | 2.05 | 1 | 0 |
Invasiveness, Neoplasm [description not available] | 0 | 2.05 | 1 | 0 |
Dermatitis, Occupational A recurrent contact dermatitis caused by substances found in the work place. | 0 | 2.05 | 1 | 0 |
Lymph Node Metastasis [description not available] | 0 | 2.44 | 2 | 0 |
Environmental Hypersensitivities [description not available] | 0 | 2.05 | 1 | 0 |
Infections, Plasmodium [description not available] | 0 | 2.05 | 1 | 0 |
Malaria A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. | 0 | 2.05 | 1 | 0 |
Airway Remodeling The structural changes in the number, mass, size and/or composition of the airway tissues. | 0 | 2.05 | 1 | 0 |
Foot Diseases Anatomical and functional disorders affecting the foot. | 0 | 2.47 | 2 | 0 |
Neoplasms, Squamous Cell Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements. | 0 | 2.06 | 1 | 0 |
Carcinoma, Anaplastic [description not available] | 0 | 2.06 | 1 | 0 |
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 2.06 | 1 | 0 |
Akinetic-Rigid Variant of Huntington Disease [description not available] | 0 | 2.98 | 1 | 0 |
Weight Reduction [description not available] | 0 | 2.98 | 1 | 0 |
Huntington Disease A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4) | 0 | 2.98 | 1 | 0 |
Weight Loss Decrease in existing BODY WEIGHT. | 0 | 2.98 | 1 | 0 |
Aphthae [description not available] | 0 | 2.06 | 1 | 0 |
Stomatitis, Aphthous A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742) | 0 | 2.06 | 1 | 0 |
Bleb [description not available] | 0 | 2.06 | 1 | 0 |
Erythema Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. | 0 | 2.06 | 1 | 0 |
Pulmonary Sarcoidosis [description not available] | 0 | 2.44 | 2 | 0 |
Sarcoidosis, Pulmonary Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431) | 0 | 2.44 | 2 | 0 |
Necrobiosis Lipoidica Diabeticorum [description not available] | 0 | 5.94 | 3 | 1 |
Necrobiosis Lipoidica A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes. | 0 | 5.94 | 3 | 1 |
Dermatitis, Irritant A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms. | 0 | 2.08 | 1 | 0 |
Deficiency of Glucose-6-Phosphate Dehydrogenase [description not available] | 0 | 2.01 | 1 | 0 |
Glucosephosphate Dehydrogenase Deficiency A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia. | 0 | 2.01 | 1 | 0 |
Cataract, Membranous [description not available] | 0 | 2.01 | 1 | 0 |
Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 2.01 | 1 | 0 |
Herpes Simplex Keratitis [description not available] | 0 | 2.42 | 2 | 0 |
Keratitis, Herpetic A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) | 0 | 2.42 | 2 | 0 |
Pityriasis Rubra Pilaris A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug. | 0 | 2.02 | 1 | 0 |
Extravascular Hemolysis [description not available] | 0 | 2.02 | 1 | 0 |
Acute Kidney Tubular Necrosis [description not available] | 0 | 2.02 | 1 | 0 |
Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. | 0 | 2.02 | 1 | 0 |
Kidney Tubular Necrosis, Acute Acute kidney failure resulting from destruction of EPITHELIAL CELLS of the KIDNEY TUBULES. It is commonly attributed to exposure to toxic agents or renal ISCHEMIA following severe TRAUMA. | 0 | 2.02 | 1 | 0 |
Liver Dysfunction [description not available] | 0 | 2.02 | 1 | 0 |
Liver Diseases Pathological processes of the LIVER. | 0 | 2.02 | 1 | 0 |
Leg Dermatoses A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed) | 0 | 3.82 | 2 | 1 |
Cyclitis, Chronic [description not available] | 0 | 2.03 | 1 | 0 |
Uveitis, Intermediate Inflammation of the pars plana, ciliary body, and adjacent structures. | 0 | 2.03 | 1 | 0 |
Cancer of Intestines [description not available] | 0 | 2.03 | 1 | 0 |
Intestinal Neoplasms Tumors or cancer of the INTESTINES. | 0 | 2.03 | 1 | 0 |
Intestinal Obstruction Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL. | 0 | 2.03 | 1 | 0 |
Experimental Hepatoma [description not available] | 0 | 2 | 1 | 0 |
Glial Cell Tumors [description not available] | 0 | 2 | 1 | 0 |
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 2 | 1 | 0 |
Cell Transformation, Viral An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. | 0 | 1.97 | 1 | 0 |