Page last updated: 2024-08-01 12:42:05

purmorphamine

Description

purmorphamine: structure in first source [MeSH]

purmorphamine : A member of the class of purines that is purine substituted at C-2 by a 1-naphthyloxy group, at C-4 by a 4-morpholinophenylamino group, and at N-9 by a cyclohexyl group. [CHeBI]

Cross-References

ID SourceID
PubMed CID5284329
CHEMBL ID1221984
SCHEMBL ID1548273
CHEBI ID63053
MeSH IDM0445467

Synonyms (60)

Synonym
chebi:63053 ,
CHEMBL1221984 ,
HSCI1_000224
MOLMAP_000073
2-(1-napthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
purmorphamine
2-(1-naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
shh signaling antagonist vi
9-cyclohexyl-n-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9h-purin-6-amine
nsc747596
nsc-747596
9-cyclohexyl-n-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine
bdbm50324671
9-cyclohexyl-n-[4-(morpholin-4-yl)phenyl]-2-(naphthalen-1-yloxy)-9h-purin-6-amine
483367-10-8
9h-purin-6-amine, 9-cyclohexyl-n-(4-(4-morpholinyl)phenyl)-2-(1-naphthalenyloxy)-
HY-15108
CS-1135
FT-0674154
NCGC00344053-01
S3042
BRD-K73397362-001-01-7
smr004701397
MLS006010334
SCHEMBL1548273
c31h32n6o2
9-cyclohexyl-n-(4-morpholinophenyl)-2-(naphthalen-1-yloxy)-9h-purin-6-amine
unii-pb12m2f8ky
DTXSID20415293
purmorphamine [mi]
9-cyclohexyl-n-(4-(4-morpholinyl)phenyl)-2-(1-naphthalenyloxy)-9h-purin-6-amine
PB12M2F8KY ,
FYBHCRQFSFYWPY-UHFFFAOYSA-N
9-cyclohexyl-n-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9h-purin-6-amine
HB3412
9-cyclohexyl-n-[4-(4-morpholinyl)ph enyl]-2-(1-naphthalenyloxy)-9h-purin-6-amine
AKOS024458218
HMS3650O20
J-519503
EX-A348
HMS3651D16
mfcd09037557
NCGC00344053-09
SW219909-1
BCP03687
purmorphamine - cas 483367-10-8
SR-01000946316-1
sr-01000946316
Q15409344
AMY20087
SB19498
9-cyclohexyl-n-[4-(morpholin-4-yl)phenyl]-2-(naphthalen-1-yloxy)-9h-purin-6 -amine
CCG-269857
A871928
gtpl10356
AS-56474
F11453
purmorphamine (gmp)
HY-15108G
CS-0626102

Roles (2)

RoleDescription
osteogenesis regulatorAny compound that induces or regulates osteogenesis.
SMO receptor agonistAn agonist that enhances the action of smoothened (SMO) receptor.

Drug Classes (4)

ClassDescription
purinesA class of imidazopyrimidines that consists of purine and its substituted derivatives.
morpholinesAny compound containing morpholine as part of its structure.
aromatic etherAny ether in which the oxygen is attached to at least one aryl substituent.
secondary amino compoundA compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups.

Protein Targets (11)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency21.3174AID1645841
EWS/FLI fusion proteinHomo sapiens (human)Potency0.0019AID1259256
GVesicular stomatitis virusPotency4.7724AID1645842
Interferon betaHomo sapiens (human)Potency4.7724AID1645842
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency4.7724AID1645842
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency4.7724AID1645842
cytochrome P450 2C9, partialHomo sapiens (human)Potency4.7724AID1645842

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Smoothened homologHomo sapiens (human)IC501.5000AID502891

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Smoothened homologMus musculus (house mouse)EC500.8000AID1321064
Sonic hedgehog proteinMus musculus (house mouse)EC501.0000AID502884

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
interferon gamma precursorHomo sapiens (human)AC5014.5550AID1259418; AID1259420

Bioassays (45)

Assay IDTitleYearJournalArticle
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
ISSN: 2472-5560
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347160Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347159Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
ISSN: 1521-0111
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
ISSN: 1521-0111
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347093qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347100qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1745845Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID1347089qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
ISSN: 2211-1247
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347090qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347096qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347106qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347107qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347102qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347104qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173ISSN: 1872-9096A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347091qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
ISSN: 1949-2553
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID509545Agonist activity at hedgehog receptor2010Bioorganic & medicinal chemistry, Sep-15, Volume: 18, Issue:18
ISSN: 1464-3391
Modulators of the hedgehog signaling pathway.
AID502890Activation of Shh in smo-expressing MEF at 0.5 uM after 30 hrs by luciferase reporter assay2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502894Ratio of EC50 for Shh in mouse Shh Light2 cells to EC50 for Shh in mouse Shh Light2 cells in presence of 100 nM 3-keto-N-aminoethyl-N'-aminocaproyldihydrocinnamoyl cyclopamine2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502889Activation of Shh in smo gene-deficient MEF at 0.5 uM after 30 hrs by luciferase reporter assay2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502885Activation of Shh in ptch1 gene-deficient MEF assessed as beta-galactosidase activity after 30 hrs by chemiluminescence assay in presence of 100 nM 3-keto-N-aminoethyl-N'-aminocaproyldihydrocinnamoyl cyclopamine2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502884Activation of Shh in mouse Shh Light2 cells after 30 hrs by luciferase reporter gene assay2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID1321065Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast at 10 uM incubated for 6 days by alkaline phosphatase assay relative to GSA-102016European journal of medicinal chemistry, Oct-04, Volume: 121ISSN: 1768-3254Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives.
AID502891Inhibition of BODIPY-cyclopamine binding to Smo expressed in HEK293T cells after 1 hr by fluorescence microscopy2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID512617Induction of osteogenesis in mouse C3H10T1/2 cells assessed as induction of osteoblast specific marker alkaline phosphatase by immunofluorescence method2005Nature chemical biology, Jul, Volume: 1, Issue:2
ISSN: 1552-4450
Diversity-oriented synthesis: exploring the intersections between chemistry and biology.
AID502892Inhibition of BODIPY-cyclopamine binding to Smo N-terminal cysteine domain expressed in HEK293T cells at 5 uM after 4 hrs by fluorescence microscopy2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502886Activation of Shh in mouse Shh Light2 cells assessed as beta-galactosidase activity after 30 hrs by luciferase reporter gene assay in presence of 100 nM 3-keto-N-aminoethyl-N'-aminocaproyldihydrocinnamoyl cyclopamine2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID502893Inhibition of BODIPY-cyclopamine binding to Smo C-terminal cytoplasmic domain expressed in HEK293T cells at 5 uM after 4 hrs by fluorescence microscopy2006Nature chemical biology, Jan, Volume: 2, Issue:1
ISSN: 1552-4450
Purmorphamine activates the Hedgehog pathway by targeting Smoothened.
AID1321064Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase assay2016European journal of medicinal chemistry, Oct-04, Volume: 121ISSN: 1768-3254Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives.
AID1347411qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary2020ACS chemical biology, 07-17, Volume: 15, Issue:7
ISSN: 1554-8937
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.

Research

Studies (88)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (17.05)29.6817
2010's62 (70.45)24.3611
2020's11 (12.50)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (3.37%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other86 (96.63%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
boheminepurinesEC 2.7.11.22 (cyclin-dependent kinase) inhibitor00low000000
8-chlorotheophyllineorganochlorine compound;
purines
central nervous system stimulant00low000000
2-fluoroadenineorganofluorine compound;
purines
antineoplastic agent00low000000
cytidylyl-3',5'-adenosinenucleoside analogue;
purines
00low000000
uridylyl-(3'-5')-adenosinenucleoside analogue;
purines
00low000000
1,n(6)-ethenodeoxyadenosinepurines00low000000
adenylyl-(2'-5')-uridinenucleoside analogue;
purines
00low000000
2-(4-morpholinoanilino)-6-cyclohexylaminopurinemorpholines;
purines;
secondary amino compound;
tertiary amino compound
adenosine A3 receptor antagonist;
antineoplastic agent;
Aurora kinase inhibitor;
cell dedifferentiation agent
00low000000
(2R,3S,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-oxolanol3'-deoxyribonucleoside;
purines
00low000000
mercaptopurinearyl thiol;
purines;
thiocarbonyl compound
anticoronaviral agent;
antimetabolite;
antineoplastic agent
00low000000
benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester3'-deoxyribonucleoside;
purines
00low000000
6-mercapto-9-(tetrahydro-2-furyl)purinepurines;
thiocarbonyl compound
00low000000
2-amino-9-pentyl-3H-purine-6-thionepurines;
thiocarbonyl compound
00low000000
9-cyclopentyl-3H-purine-6-thionepurines;
thiocarbonyl compound
00low000000
6-methylpurinepurinesEC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor00low000000
6-chloropurinepurines00low000000
2'-deoxyadenylyl-(3'-5')-2'-deoxyadenosinenucleoside analogue;
purines
00low000000
idelalisibaromatic amine;
organofluorine compound;
purines;
quinazolines;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
00low000000
agrocin 84purines00low000000
4-[[9-[(3R)-3-oxolanyl]-8-(2,4,6-trifluoroanilino)-2-purinyl]amino]-1-cyclohexanolpurines00low000000
valganciclovirL-valyl ester;
purines
antiviral drug;
prodrug
00low000000
5-(4-methoxyphenyl)-6-sulfanylidene-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-oneorganosulfur compound;
purines
00low000000
guanylyl-(3'-5')-guanosinenucleoside analogue;
purines
00low000000
2'-deoxyguanylyl-(3'-5')-2'-deoxycytidinenucleoside analogue;
purines
00low000000
guanine ribonucleotidyl-(3'-5')-adenosinenucleoside analogue;
purines
00low000000
dimorpholaminemorpholines;
ureas
00low000000
1-phenyl-2-palmitoylamino-3-morpholino-1-propanolbenzyl alcohols;
fatty amide;
morpholines;
secondary alcohol;
tertiary amino compound
00low000000
doxaprammorpholines;
pyrrolidin-2-ones
central nervous system stimulant00low000000
hemicholinium 3morpholines00low000000
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-onechromones;
morpholines;
organochlorine compound
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
00low000000
minaprinemorpholines;
pyridazines;
secondary amine
antidepressant;
antiparkinson drug;
cholinergic drug;
dopamine uptake inhibitor;
serotonin uptake inhibitor
00low000000
moclobemidebenzamides;
monochlorobenzenes;
morpholines
antidepressant;
environmental contaminant;
xenobiotic
00low000000
molsidomineethyl ester;
morpholines;
oxadiazole;
zwitterion
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent
00low000000
phenmetrazinemorpholinesmetabolite;
sympathomimetic agent
00low000000
pramoxinearomatic ether;
morpholines
local anaesthetic00low000000
linsidominemorpholines00low000000
morpholinemorpholines;
saturated organic heteromonocyclic parent
NMR chemical shift reference compound00low000000
trimetozinemorpholines00low000000
trifenmorphmorpholines00low000000
fenbutrazatemorpholines00low000000
tridemorphmorpholines;
tertiary amino compound
antifungal agrochemical00low000000
moricizinecarbamate ester;
morpholines;
phenothiazines
anti-arrhythmia drug00low000000
morazonemorpholines00low000000
delmopinolmorpholines00low000000
3-morpholinopropylaminemorpholines;
primary amino compound
00low000000
morzidmorpholines00low000000
methoxy-morpholinyl-doxorubicinanthracycline antibiotic;
morpholines;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone
00low000000
morphazinamidemorpholines;
pyrazines;
secondary carboxamide
00low000000
morpholinopropane sulfonic acidMOPS;
morpholines;
organosulfonic acid
00low000000
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimidecarbodiimide;
morpholines
cross-linking reagent00low000000
dextromoramidemorpholines;
N-acylpyrrolidine
opioid analgesic00low000000
landiololmorpholines00low000000
mosapridearomatic ether;
benzamides;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
secondary carboxamide;
substituted aniline;
tertiary amino compound
00low000000
gefitinibaromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
epidermal growth factor receptor antagonist
00low000000
pre 084morpholines00low000000
xamoterolmorpholines00low000000
canertinibmonochlorobenzenes;
morpholines;
organofluorine compound;
quinazolines
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
birb 796aromatic ether;
morpholines;
naphthalenes;
pyrazoles;
ureas
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
immunomodulator
00low000000
Landiolol hydrochloridemorpholines00low000000
4-2-Aminoethyl-morpholinemorpholines00low000000
rocuronium3alpha-hydroxy steroid;
acetate ester;
androstane;
morpholines;
quaternary ammonium ion;
tertiary amino compound
drug allergen;
muscle relaxant;
neuromuscular agent
00low000000
linezolidacetamides;
morpholines;
organofluorine compound;
oxazolidinone
antibacterial drug;
protein synthesis inhibitor
00low000000
cp-640186anthracenes;
bipiperidines;
morpholines;
N-acylpiperidine
00low000000
4-Morpholinyl(4-pentylcyclohexyl)methanonemorpholines00low000000
2-[5-[4-(dimethylamino)phenyl]-2-tetrazolyl]-N-[2-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
2-[[5-(4-fluorophenyl)-1-methyl-2-imidazolyl]thio]-N-[2-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
2-(2,4-dioxo-3-thiazolidinyl)-N-[4-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
N-(2-methylphenyl)-2-[5-[4-(4-morpholinyl)phenyl]-2-tetrazolyl]acetamidemorpholines00low000000
5-[4-morpholinyl(oxo)methyl]-2-pyranonemorpholines00low000000
5-(1,3-benzodioxol-5-ylmethylamino)-2-(4-morpholinyl)benzoic acid methyl estermorpholines00low000000
N-[4-(4-morpholinyl)phenyl]-2-thiophenesulfonamidemorpholines00low000000
4-(4-morpholinyl)-N-(pyridin-4-ylmethyl)anilinemorpholines00low000000
[4-amino-3-(4-methylphenyl)-2-sulfanylidene-5-thiazolyl]-(4-morpholinyl)methanonemorpholines00low000000
2-(1,3-dimethyl-2,6-dioxo-9-purinyl)-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]acetamidemorpholines00low000000
DND-167 dyemorpholinesfluorochrome00low000000
1-(2,1,3-benzothiadiazol-5-yl)-3-[4-(4-morpholinyl)phenyl]ureamorpholines00low000000
2-(4-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-quinazolinaminemorpholines00low000000
2-(3-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-quinazolinaminemorpholines00low000000
1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-[4-(4-morpholinyl)phenyl]thioureamorpholines00low000000
1-[5-(5-chloro-2-methylphenyl)-2-furanyl]-N-[4-(4-morpholinyl)phenyl]methaniminemorpholines00low000000
N-[4-(4-morpholinyl)phenyl]carbamic acid butyl estermorpholines00low000000
2-(2,4-dioxo-1H-pyrimidin-6-yl)-N-[2-(4-morpholinyl)ethyl]acetamidemorpholines;
pyrimidone;
secondary carboxamide;
tertiary amino compound
00low000000
1-(4-butylphenyl)-3-(4-morpholinyl)thioureamorpholines00low000000
5-[[2-methoxy-4-(4-morpholinyl)phenyl]methylidene]-1,3-diazinane-2,4,6-trionemorpholines00low000000
N-[2,2-dichloro-1-(3-fluoro-4-methylphenyl)ethenyl]-4-morpholinecarboxamidemorpholines00low000000
2-(methylthio)-3-pyridinecarboxylic acid [2-[2-(4-morpholinyl)-5-(trifluoromethyl)anilino]-2-oxoethyl] estermorpholines00low000000
2-[(2-hydroxy-1-naphthalenyl)methyl-methylamino]-N-[4-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
N-(2,5-diethoxy-4-morpholinophenyl)acetamidemorpholines00low000000
Benzo[b]thiophen-2-yl(morpholino)methanonemorpholines00low000000
5-(4-morpholinoanilino)-5-oxo-3-phenylpentanoic acidmorpholines00low000000
N-(2-morpholinophenyl)-N'-phenylureamorpholines00low000000
N,N'-di[4-(2,6-dimethylmorpholino)phenyl]thioureamorpholines00low000000
3,5,7-trimethyl-N-[4-morpholinyl(sulfanylidene)methyl]-1-adamantanecarboxamidemorpholines00low000000
N-[2-(3-methylphenoxy)ethyl]-5-(4-morpholinyl)-2-nitroanilinemorpholines00low000000
N-[2-(4-methoxyphenoxy)ethyl]-5-(4-morpholinyl)-2-nitroanilinemorpholines00low000000
[3-[(2-chlorophenoxy)methyl]phenyl]-(2,6-dimethyl-4-morpholinyl)methanonemorpholines00low000000
2,6-dimethyl-4-thiophen-2-ylsulfonylmorpholinemorpholines00low000000
1-[4-(dimethylamino)phenyl]-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dionemorpholines00low000000
1-(2,4-dimethoxyphenyl)-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dionemorpholines00low000000
N-[3-chloro-4-(4-morpholinyl)phenyl]-1,1-dioxo-1,2-benzothiazol-3-aminemorpholines00low000000
7-[(2,6-dimethyl-4-morpholinyl)methyl]-5-thiazolo[3,2-a]pyrimidinonemorpholines;
thiazolopyrimidine
00low000000
3-(4-chlorophenyl)sulfonyl-N-[2,5-diethoxy-4-(4-morpholinyl)phenyl]propanamidemorpholines00low000000
3-(methanesulfonamido)benzoic acid [1-[4-(4-morpholinyl)anilino]-1-oxopropan-2-yl] estermorpholines00low000000
2-(4-chloro-2-methylphenoxy)-N-[2-(4-morpholinyl)phenyl]propanamidemorpholines00low000000
3-amino-5-morpholinomethyl-2-oxazolidinonemorpholines;
oxazolidinone
marine xenobiotic metabolite;
xenobiotic metabolite
00low000000
5-ethyl-2-[[[3-(4-morpholinyl)-4-nitrophenyl]-oxomethyl]amino]-3-thiophenecarboxylic acid ethyl estermorpholines00low000000
1-methyl-N-[4-(4-morpholinyl)phenyl]-2-quinoliniminemorpholines00low000000
4-morpholinecarboxylic acid [3-(6-amino-5-cyano-3-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)phenyl] estermorpholines;
pyranopyrazole
00low000000
4-morpholinecarboxylic acid [3-(6-amino-5-cyano-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)phenyl] estermorpholines;
pyranopyrazole
00low000000
(4-amino-3-ethyl-2-sulfanylidene-5-thiazolyl)-(4-morpholinyl)methanonemorpholines00low000000
LSM-19878morpholines00low000000
2-(4-morpholinyl)-5-(1-piperidinylsulfonyl)benzoic acid [2-[2-(4-fluorophenyl)ethylamino]-2-oxoethyl] estermorpholines00low000000
4-(4-morpholinyl)-3-nitro-N-(2-thiazolyl)benzamidemorpholines00low000000
2-(1-adamantyl)-N-[2,5-diethoxy-4-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
2-[2,5-diethoxy-4-(4-morpholinyl)anilino]-1-(4-methyl-1-piperidinyl)-1-propanonemorpholines00low000000
[4-[bis(4-morpholinyl)phosphoryl]-1-methyl-2-pyrrolyl]-bis(4-morpholinyl)-sulfanylidenephosphoranemorpholines00low000000
5-benzoyl-6-methyl-4-[4-(4-morpholinyl)phenyl]-3,4-dihydro-1H-pyrimidin-2-onemorpholines00low000000
(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanonemorpholines;
naphthyl ketone;
organic heterotricyclic compound;
synthetic cannabinoid
analgesic;
apoptosis inhibitor;
neuroprotective agent
00low000000
molsidomineethyl ester;
morpholines;
oxadiazole;
zwitterion
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent
00low000000
DPI2benzenes;
morpholines;
secondary carboxamide;
tertiary amino compound;
thiazolidinone
ferroptosis inducer00low000000
N-(3-methylphenyl)-4-[4-(4-morpholinyl)-3-nitrophenyl]-1-phthalazinaminemorpholines00low000000
rivaroxabanaromatic amide;
lactam;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
oxazolidinone;
thiophenes
anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
00low000000
pi103aromatic amine;
morpholines;
organic heterotricyclic compound;
phenols;
tertiary amino compound
antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
00low000000
zm 447439aromatic ether;
benzamides;
morpholines;
polyether;
quinazolines;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor
00low000000
tae226morpholines00low000000
flumorpharomatic ether;
enamide;
morpholines;
organofluorine compound;
tertiary carboxamide
00low000000
epoxomicinmorpholines;
tripeptide
proteasome inhibitor00low000000
MI-63azaspiro compound;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
oxindoles;
pyrrolidines;
secondary carboxamide
apoptosis inducer00low000000
chir 090acetylenic compound;
benzamides;
hydroxamic acid;
L-threonine derivative;
morpholines
antimicrobial agent;
EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor;
lipopolysaccharide biosynthesis inhibitor
00low000000
carfilzomibepoxide;
morpholines;
tetrapeptide
antineoplastic agent;
proteasome inhibitor
00low000000
zstk474benzimidazoles;
morpholines;
organofluorine compound;
triamino-1,3,5-triazine
antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
00low000000
1-(4-bromophenyl)-3-[[[4-(4-morpholinyl)-3-nitrophenyl]-oxomethyl]amino]thioureamorpholines00low000000
4-[(2-heptan-3-yl-1,3-dioxolan-4-yl)methyl]-4-methylmorpholin-4-iummorpholines00low000000
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(4-morpholinyl)phenyl]-3-imidazo[1,2-a]pyrazinaminemorpholines00low000000
buparlisibaminopyridine;
aminopyrimidine;
morpholines;
organofluorine compound
antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
00low000000
ku 0063794benzyl alcohols;
monomethoxybenzene;
morpholines;
pyridopyrimidine;
tertiary amino compound
antineoplastic agent;
mTOR inhibitor
00low000000
gdc 0941indazoles;
morpholines;
piperazines;
sulfonamide;
thienopyrimidine
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor00low000000
lde225aminopyridine;
aromatic ether;
benzamides;
biphenyls;
morpholines;
organofluorine compound;
tertiary amino compound
antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist
00low000000
quizartinibbenzoimidazothiazole;
isoxazoles;
morpholines;
phenylureas
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
necroptosis inhibitor
00low000000
navitoclaxaryl sulfide;
monochlorobenzenes;
morpholines;
N-sulfonylcarboxamide;
organofluorine compound;
piperazines;
secondary amino compound;
sulfone;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
00low000000
n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamideaminopyrimidine;
benzamides;
morpholines;
nitrile;
secondary amino compound;
tertiary amino compound
anti-anaemic agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
00low000000
cobicistat1,3-thiazoles;
carbamate ester;
monocarboxylic acid amide;
morpholines;
ureas
P450 inhibitor00low000000
(5-(2,4-bis((3s)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanolbenzyl alcohols;
morpholines;
pyridopyrimidine;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
mTOR inhibitor
00low000000
alectinibaromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
3-fluorophenmetrazinemorpholines00low000000
HG-10-102-01aminopyrimidine;
aromatic ether;
monocarboxylic acid amide;
morpholines;
organochlorine compound;
secondary amino compound
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
MLI-2aromatic ether;
cyclopropanes;
indazoles;
morpholines;
pyrimidines;
tertiary amino compound
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
aprepitant(trifluoromethyl)benzenes;
cyclic acetal;
morpholines;
triazoles
antidepressant;
antiemetic;
neurokinin-1 receptor antagonist;
peripheral nervous system drug;
substance P receptor antagonist
00low000000
fosaprepitant(trifluoromethyl)benzenes;
cyclic acetal;
morpholines;
phosphoramide;
triazoles
antiemetic;
neurokinin-1 receptor antagonist;
prodrug
00low000000
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-[4-(4-morpholinyl)phenyl]acetamidemorpholines00low000000
ver 52296aromatic amide;
isoxazoles;
monocarboxylic acid amide;
morpholines;
resorcinols
angiogenesis inhibitor;
antineoplastic agent;
Hsp90 inhibitor
00low000000
2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrilehydroxyindoles;
morpholines;
nitrile;
pyridines;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
tau aggregation inhibitor
00low000000
quinacrineacridines;
aromatic ether;
organochlorine compound;
tertiary amino compound
antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
00low000000
vanilmandelic acid2-hydroxy monocarboxylic acid;
aromatic ether;
phenols
human metabolite00low000000
4-(2,4-dichlorophenoxy)butyric acidaromatic ether;
monocarboxylic acid;
organochlorine compound
agrochemical;
phenoxy herbicide;
synthetic auxin
00low000000
win 52035aromatic ether00low000000
win 52084aromatic ether00low000000
5-(nonyloxy)tryptaminearomatic ether;
primary amino compound;
tryptamines
serotonergic agonist00low000000
methylbufoteninaromatic ether;
tertiary amino compound;
tryptamine alkaloid
hallucinogen;
plant metabolite
00low000000
5-methoxytryptaminearomatic ether;
primary amino compound;
tryptamines
5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist
00low000000
ro 48-8071aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound
antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor
00low000000
rtki cpdaromatic ether;
monochlorobenzenes;
quinazolines
antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector
00low000000
amsacrineacridines;
aromatic ether;
sulfonamide
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
00low000000
aristolochic acid iaristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound
carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
00low000000
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-onearomatic ether;
benzoxazine;
cyclic hydroxamic acid;
lactol
allelochemical;
plant metabolite
00low000000
bufetololaromatic ether00low000000
bufexamacaromatic ether;
hydroxamic acid
antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
bunitrololaromatic ether00low000000
bupranololaromatic ether00low000000
verapamilaromatic ether;
nitrile;
polyether;
tertiary amino compound
00low000000
cgp 12177aromatic ether;
benzimidazoles;
secondary alcohol;
secondary amino compound
beta-adrenergic antagonist00low000000
ciglitazonearomatic ether;
thiazolidinone
antineoplastic agent;
insulin-sensitizing drug
00low000000
cirazolinearomatic ether00low000000
clofibratearomatic ether;
ethyl ester;
monochlorobenzenes
anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
00low000000
clofibric acidaromatic ether;
monocarboxylic acid;
monochlorobenzenes
anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist
00low000000
colchicine, (+-)-isomeracetamides;
alkaloid;
aromatic ether;
carbotricyclic compound
microtubule-destabilising agent;
plant metabolite
00low000000
croconazolearomatic ether;
conazole antifungal drug;
imidazole antifungal drug;
monochlorobenzenes
00low000000
cypermethrinaromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound
agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide
00low000000
racemethorphanaromatic ether;
morphinane alkaloid;
morphinane-like compound;
organic heterotetracyclic compound
00low000000
dibucainearomatic ether;
monocarboxylic acid amide;
tertiary amino compound
topical anaesthetic00low000000
dilacor xracetate ester;
aromatic ether;
benzothiazepine;
lactam;
tertiary amino compound
00low000000
domiphenaromatic ether00low000000
donepezilaromatic ether;
indanones;
piperidines;
racemate
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
00low000000
epirizolearomatic ether00low000000
ethacrynic acidaromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid
EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
00low000000
ethoxyquinaromatic ether;
quinolines
antifungal agrochemical;
food antioxidant;
genotoxin;
geroprotector;
herbicide;
Hsp90 inhibitor;
neuroprotective agent;
UDP-glucuronosyltransferase activator
00low000000
ethoxzolamidearomatic ether;
benzothiazoles;
sulfonamide
antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
00low000000
2-hexyloxybenzamidearomatic ether;
benzamides
antifungal agent00low000000
carbonyl cyanide p-trifluoromethoxyphenylhydrazonearomatic ether;
hydrazone;
nitrile;
organofluorine compound
ATP synthase inhibitor;
geroprotector;
ionophore
00low000000
fenofibratearomatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes
antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
00low000000
fenvaleratearomatic ether;
carboxylic ester;
monochlorobenzenes
pyrethroid ester acaricide;
pyrethroid ester insecticide
00low000000
flecainidearomatic ether;
monocarboxylic acid amide;
organofluorine compound;
piperidines
anti-arrhythmia drug00low000000
fluoxetine(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound
00low000000
gallamine triethiodidearomatic ether00low000000
gemfibrozilaromatic etherantilipemic drug00low000000
haloproginaromatic ether00low000000
indomethacinaromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole
analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
00low000000
ipriflavonearomatic ether;
isoflavones
bone density conservation agent00low000000
ly 171883acetophenones;
aromatic ether;
phenols;
tetrazoles
anti-asthmatic drug;
leukotriene antagonist
00low000000
mephenesinaromatic ether;
glycerol ether
00low000000
methocarbamolaromatic ether;
carbamate ester;
secondary alcohol
00low000000
methoctraminearomatic ether;
tetramine
muscarinic antagonist00low000000
methoxsalenaromatic ether;
psoralens
antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite
00low000000
metoprololaromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic
00low000000
mexiletinearomatic ether;
primary amino compound
anti-arrhythmia drug00low000000
midodrineamino acid amide;
aromatic ether;
secondary alcohol
alpha-adrenergic agonist;
prodrug;
sympathomimetic agent;
vasoconstrictor agent
00low000000
clorgylinearomatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound
antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor
00low000000
nefazodonearomatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles
alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor
00low000000
nimesulidearomatic ether;
C-nitro compound;
sulfonamide
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
00low000000
nisoxetinearomatic ether;
secondary amino compound
adrenergic uptake inhibitor;
antidepressant
00low000000
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamidearomatic ether;
C-nitro compound;
sulfonamide
antineoplastic agent;
cyclooxygenase 2 inhibitor
00low000000
omeprazolearomatic ether;
benzimidazoles;
pyridines;
sulfoxide
00low000000
oxprenololaromatic ether00low000000
pantoprazolearomatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide
anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic
00low000000
pd 153035aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist
00low000000
pentamidinearomatic ether;
carboxamidine;
diether
anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
00low000000
phenacetinacetamides;
aromatic ether
cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
00low000000
pioglitazonearomatic ether;
pyridines;
thiazolidinediones
antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic
00low000000
piretanidearomatic ether00low000000
prazosinaromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines
alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
00low000000
primaquineaminoquinoline;
aromatic ether;
N-substituted diamine
antimalarial00low000000
proglumetacinaromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine
antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug
00low000000
propoxuraromatic ether;
carbamate ester
acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
00low000000
pyrilaminearomatic ether;
ethylenediamine derivative
H1-receptor antagonist00low000000
sulfadimethoxinearomatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide
antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
00low000000
tetrahydropapaverinearomatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
polyether;
secondary amino compound
00low000000
tiloronearomatic ether;
diether;
fluoren-9-ones;
tertiary amino compound
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
interferon inducer;
nicotinic acetylcholine receptor agonist
00low000000
ultramaromatic ether;
tertiary alcohol;
tertiary amino compound
00low000000
triclosanaromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols
antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic
00low000000
viloxazinearomatic ether00low000000
wb 4101aromatic ether;
benzodioxine;
secondary amino compound
alpha-adrenergic antagonist00low000000
3,3',5-triiodothyropropionic acidaromatic ether00low000000
methacetinacetamides;
aromatic ether
00low000000
mestranol17beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound
prodrug;
xenoestrogen
00low000000
visnaginaromatic ether;
furanochromone;
polyketide
anti-inflammatory agent;
antihypertensive agent;
EC 1.1.1.37 (malate dehydrogenase) inhibitor;
phytotoxin;
plant metabolite;
vasodilator agent
00low000000
2-tert-butyl-4-hydroxyanisolearomatic ether;
phenols
00low000000
mecoproparomatic ether;
monocarboxylic acid;
monochlorobenzenes
00low000000
phenetidinearomatic ether;
substituted aniline
00low000000
2-methyl-4-chlorophenoxy gamma-butyric acidaromatic ether;
monocarboxylic acid;
monochlorobenzenes
environmental contaminant;
phenoxy herbicide;
xenobiotic
00low000000
4-bromophenyl phenyl etheraromatic ether;
organobromine compound
00low000000
di-(4-aminophenyl)etheraromatic ether00low000000
phenyl etheraromatic etherplant metabolite00low000000
diglycidyl resorcinol etheraromatic ether00low000000
phenetolearomatic ether00low000000
scoparonearomatic ether;
coumarins
anti-allergic agent;
anti-inflammatory agent;
antihypertensive agent;
antilipemic drug;
immunosuppressive agent;
plant metabolite
00low000000
dimethoxyphenylethylaminealkaloid;
aromatic ether;
phenylethylamine
allergen;
plant metabolite
00low000000
dichlorproparomatic ether;
dichlorobenzene;
monocarboxylic acid
00low000000
3-tert-butyl-4-hydroxyanisolearomatic ether;
phenols
antioxidant;
human xenobiotic metabolite
00low000000
ethyl vanillinaromatic ether;
benzaldehydes;
phenols
antioxidant;
flavouring agent
00low000000
benzethonium chloridearomatic ether;
chloride salt;
quaternary ammonium salt
antibacterial agent;
antifungal agent;
antiseptic drug;
antiviral agent;
disinfectant
00low000000
peucedaninaromatic ether;
furanocoumarin;
lactone
plant metabolite00low000000
phenetidinearomatic ether;
primary amino compound;
substituted aniline
drug metabolite00low000000
6-methoxybenzoxazolinonearomatic ether;
benzoxazole
antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite
00low000000
3-anisidinearomatic ether;
substituted aniline
00low000000
domiphen bromidearomatic ether00low000000
dibrompropamidinearomatic ether00low000000
4-Ethoxyphenolaromatic ether;
phenols
00low000000
bulbocapnineaporphine alkaloid;
aromatic ether;
oxacycle;
phenols
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
EC 1.4.3.22 (diamine oxidase) inhibitor;
plant metabolite
00low000000
benzydaminearomatic ether;
indazoles;
tertiary amino compound
analgesic;
central nervous system stimulant;
hallucinogen;
local anaesthetic;
non-steroidal anti-inflammatory drug
00low000000
xylocholinearomatic ether00low000000
3-methoxycatecholaromatic ether;
catechols
G-protein-coupled receptor agonist00low000000
2-phenoxypropanoic acidaromatic ether;
carboxylic acid
00low000000
6-methoxyquinolinearomatic ether;
quinolines
00low000000
metaxalonearomatic ether00low000000
heliaminearomatic ether;
diether;
isoquinoline alkaloid;
isoquinolines
plant metabolite00low000000
2,4,6-trichlorophenyl 4-nitrophenyl etheraromatic ether;
C-nitro compound;
chlorobenzenes
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
00low000000
etridiazolaromatic ether;
organochlorine compound;
thiadiazole antifungal agent;
thiadiazoles
antifungal agrochemical;
nitrification inhibitor
00low000000
toliprololaromatic ether00low000000
5-methoxyindoleacetic acidaromatic ether;
indole-3-acetic acids
antibacterial agent;
Brassica napus metabolite;
carcinogenic agent;
human urinary metabolite;
marine xenobiotic metabolite;
rat metabolite
00low000000
iproclozidearomatic ether00low000000
phenoxyacetic acidaromatic ether;
monocarboxylic acid
allergen;
Aspergillus metabolite;
human xenobiotic metabolite;
plant growth retardant
00low000000
nafenopinaromatic ether;
monocarboxylic acid
00low000000
methyl vanillatearomatic ether;
benzoate ester;
phenols
antioxidant;
plant metabolite
00low000000
5-methoxyindole-2-carboxylic acidaromatic ether;
indolecarboxylic acid
EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor;
hypoglycemic agent;
plant metabolite
00low000000
2-isopropoxyphenolaromatic ether;
phenols
00low000000
dehydroemetinearomatic ether;
isoquinolines;
pyridoisoquinoline
antileishmanial agent;
antimalarial;
antiprotozoal drug
00low000000
1,2-epoxy-3-(p-nitrophenoxy)propanearomatic ether;
C-nitro compound;
epoxide
00low000000
laurolitsineaporphine alkaloid;
aromatic ether;
phenols
HIV-1 integrase inhibitor;
metabolite
00low000000
metocurine iodidearomatic ether00low000000
ac 45594aromatic ether00low000000
3-phenoxybenzylalcoholaromatic ether;
benzyl alcohols
marine xenobiotic metabolite00low000000
devrinolaromatic ether;
monocarboxylic acid amide;
naphthalenes
00low000000
fluorodifenaromatic ether00low000000
acridine half-mustardaminoacridines;
aromatic ether;
organochlorine compound;
secondary amino compound
mutagen00low000000
precocene iaromatic ether;
chromenes
plant metabolite;
precocenes
00low000000
oxadiazonaromatic ether00low000000
lofexidinearomatic ether;
carboxamidine;
dichlorobenzene;
imidazoles
alpha-adrenergic agonist;
antihypertensive agent
00low000000
alclofenacaromatic ether;
monocarboxylic acid;
monochlorobenzenes
drug allergen;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
phenylglycidyl etheraromatic ether00low000000
phenoxyethanolaromatic ether;
glycol ether;
primary alcohol
antiinfective agent;
central nervous system depressant
00low000000
metipranololacetate ester;
aromatic ether;
propanolamine;
secondary amino compound
anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
00low000000
silybinaromatic ether;
benzodioxine;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone
antineoplastic agent;
antioxidant;
hepatoprotective agent;
plant metabolite
00low000000
oxamethacinaromatic ether;
hydroxamic acid;
N-acylindole;
organochlorine compound
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
canadinearomatic ether;
berberine alkaloid;
organic heteropentacyclic compound;
oxacycle
00low000000
7-ethoxycoumarinaromatic ether;
coumarins
00low000000
medifoxaminearomatic ether00low000000
chlormethoxynilaromatic ether00low000000
climbazolearomatic ether;
hemiaminal ether;
imidazoles;
ketone;
monochlorobenzenes
00low000000
4-hexyloxyanilinearomatic ether;
substituted aniline
00low000000
ticrynafenaromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes
antihypertensive agent;
hepatotoxic agent;
loop diuretic
00low000000
2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acidaromatic ether;
dichlorobenzene;
diether;
monocarboxylic acid
00low000000
bezafibratearomatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes
antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
00low000000
oxyfluorofenaromatic etherEC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
00low000000
triadimefonaromatic ether;
hemiaminal ether;
ketone;
monochlorobenzenes;
triazoles
00low000000
levobunololaromatic ether;
cyclic ketone;
propanolamine
antiglaucoma drug;
beta-adrenergic antagonist
00low000000
dichlorfop-methylaromatic ether;
dichlorobenzene;
diether;
methyl ester
00low000000
decamethrinaromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound
agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide
00low000000
triadimenolaromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide
antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite
00low000000
triclopyraromatic ether;
chloropyridine;
monocarboxylic acid
agrochemical;
environmental contaminant;
herbicide;
xenobiotic
00low000000
prenalterolaromatic ether00low000000
st 1059aromatic ether;
primary amino compound;
secondary alcohol
alpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent
00low000000
paroxetinearomatic ether;
benzodioxoles;
organofluorine compound;
piperidines
antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor
00low000000
acifluorfenaromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound
agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
00low000000
bopindololaromatic ether;
benzoate ester;
methylindole;
secondary amino compound
00low000000
fenpropathrin, (+-)-isomeraromatic ether;
cyclopropanecarboxylate ester
agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
00low000000
triflumuronaromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound
00low000000
flutolanil(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
benzanilide fungicide
antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
00low000000
fenoxaprop ethylaromatic ether00low000000
triclabendazolearomatic ether00low000000
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acidaminopyridine;
aromatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound
environmental contaminant;
herbicide;
xenobiotic
00low000000
fluvalinate(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide
agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
00low000000
haloxyfoparomatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines
00low000000
fluazifop-butylaromatic ether;
carboxylic ester;
organofluorine compound;
pyridines
00low000000
fomesafenaromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols
agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
00low000000
fenoxycarbaromatic ether;
carbamate ester
environmental contaminant;
insecticide;
juvenile hormone mimic;
xenobiotic
00low000000
quizalofop-ethylaromatic ether;
ethyl ester;
organochlorine compound;
quinoxaline derivative
00low000000
cetamololaromatic ether00low000000
atomoxetinearomatic ether;
secondary amino compound;
toluenes
adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
00low000000
methyl bensulfuronaromatic ether;
methyl ester;
N-sulfonylurea;
pyrimidines
agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
00low000000
itraconazolearomatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor
00low000000
loxtidinearomatic ether;
piperidines;
primary alcohol;
triazoles
H2-receptor antagonist00low000000
disoxarilaromatic ether00low000000
chlorimuron ethylaromatic ether;
ethyl ester;
N-sulfonylurea;
organochlorine pesticide;
pyrimidines;
sulfamoylbenzoate
agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide
00low000000
tepoxalinaromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles
antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
esmololaromatic ether;
ethanolamines;
methyl ester;
secondary alcohol;
secondary amino compound
00low000000
pioglitazone hydrochloridearomatic ether00low000000
aripiprazolearomatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone
drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist
00low000000
sulfametrolearomatic ether;
substituted aniline;
sulfonamide antibiotic;
thiadiazoles
00low000000
propamidinearomatic ether;
guanidines;
polyether
antimicrobial agent;
antiseptic drug
00low000000
hexamidinearomatic ether;
guanidines;
polyether
antimicrobial agent;
antiseptic drug
00low000000
o-4-methylthyminearomatic ether;
methylthymine
human metabolite00low000000
fenclofenacaromatic ether00low000000
tetraiodothyroacetic acid2-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid
apoptosis inducer;
human metabolite;
thyroid hormone
00low000000
fluazuronaromatic ether;
chloropyridine;
monochlorobenzenes;
N-acylurea;
organochlorine acaricide;
organofluorine acaricide;
phenylureas
acaricide;
mite growth regulator
00low000000
etiroxatearomatic ether00low000000
etofamidearomatic ether00low000000
d 888aromatic ether;
nitrile;
tertiary amino compound
anti-arrhythmia drug;
calcium channel blocker;
vasodilator agent
00low000000
esreboxetinearomatic ether00low000000
guaetholaromatic ether;
phenols;
volatile organic compound
flavouring agent00low000000
spiramidearomatic ether;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound
dopaminergic antagonist;
serotonergic antagonist
00low000000
5'-nitro-2'-propoxyacetanilidearomatic ether;
C-nitro compound
00low000000
suberosinaromatic ether;
coumarins
anticoagulant;
plant metabolite
00low000000
4-methoxyestradiol17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols
estrogen;
human metabolite;
rat metabolite
00low000000
toltrazurilaromatic ether00low000000
plafibridearomatic ether00low000000
cinitapridearomatic ether;
C-nitro compound
00low000000
isoscopoletinaromatic ether;
hydroxycoumarin
plant metabolite00low000000
ethofenproxaromatic etherpyrethroid ether insecticide00low000000
uk 68798aromatic ether;
sulfonamide;
tertiary amino compound
anti-arrhythmia drug;
potassium channel blocker
00low000000
hp 8731,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound
dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
00low000000
fenoxypropazinearomatic ether00low000000
fluphenacuraromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound
00low000000
ameziniumaromatic ether;
primary arylamine;
pyridazinium ion
adrenergic uptake inhibitor;
antihypotensive agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
sympathomimetic agent
00low000000
rubrofusarinaromatic ether;
benzochromenone;
phenols;
polyketide
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
fungal metabolite
00low000000
triasulfuron1,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound
agrochemical;
herbicide
00low000000
dauricinearomatic ether;
bisbenzylisoquinoline alkaloid;
isoquinolines;
phenols;
tertiary amino compound
plant metabolite00low000000
uvaretinaromatic ether;
dihydrochalcones;
polyketide;
resorcinol
antineoplastic agent;
plant metabolite
00low000000
fangchinolinearomatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle
anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite
00low000000
prochlorazamide fungicide;
aromatic ether;
conazole fungicide;
imidazole fungicide;
imidazoles;
trichlorobenzene;
ureas
antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
00low000000
stictic acidaromatic ether00low000000
pramoxine hydrochloridearomatic ether00low000000
4-methoxybenzylaminearalkylamino compound;
aromatic ether;
primary amino compound
00low000000
xanthurenic acid 8-methyl etheraromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid
carcinogenic agent;
metabolite;
mouse metabolite
00low000000
adriamycinolaminoglycoside;
anthracycline antibiotic;
aromatic ether;
deoxy hexoside;
p-quinones;
phenols;
polyol;
tetracenequinones
cardiotoxic agent;
drug metabolite
00low000000
difenoconazolearomatic ether;
conazole fungicide;
cyclic ketal;
dioxolane;
triazole fungicide;
triazoles
antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic
00low000000
a 8947aromatic ether;
biaryl;
N-sulfonylurea;
pyrazole pesticide;
tetrazoles
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
00low000000
thifluzamide1,3-thiazoles;
anilide fungicide;
aromatic amide;
aromatic ether;
dibromobenzene;
organofluorine compound
antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
00low000000
ethylhydrocupreinearomatic ether;
cinchona alkaloid
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor00low000000
7,8-dihydromethysticin2-pyranones;
aromatic ether
00low000000
4,5-dimethoxy-2-nitrobenzaldehydearomatic ether;
C-nitro compound
00low000000
bisphenol f diglycidyl etheraromatic ether;
diarylmethane;
epoxide
00low000000
oryzemate1,2-benzisothiazole;
aromatic ether;
benzothiazole fungicide;
sulfone
antifungal agrochemical;
plant activator
00low000000
bitertanolaromatic ether;
biphenyls;
secondary alcohol;
triazoles
00low000000
fluazifoparomatic ether;
monocarboxylic acid;
organofluorine compound;
pyridines
00low000000
diflufenican(trifluoromethyl)benzenes;
aromatic ether;
pyridinecarboxamide
carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
00low000000
hexafluoronaromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organochlorine insecticide;
organofluorine insecticide
00low000000
diethofencarbaromatic ether;
carbamate ester;
carbanilate fungicide
antifungal agrochemical00low000000
pyriproxyfenaromatic ether;
pyridines
juvenile hormone mimic00low000000
methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoatearomatic ether;
benzoate ester;
diamino-1,3,5-triazine;
methyl ester;
N-sulfonylurea
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
00low000000
dpx e9636aromatic ether;
N-sulfonylurea;
pyridines;
pyrimidines;
sulfone
environmental contaminant;
herbicide;
xenobiotic
00low000000
aclonifenaromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline
agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
00low000000
cinosulfuronaromatic ether00low000000
clodinafop-propargylaromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines
agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide
00low000000
triflusulfuron-methyl1,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound
agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide
00low000000
vestitolaromatic ether;
hydroxyisoflavans;
methoxyisoflavan
anti-inflammatory agent;
phytoalexin;
plant metabolite
00low000000
laudaninearomatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
phenols;
racemate
00low000000
cryptopleurinealkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound
antineoplastic agent;
antiviral agent;
protein synthesis inhibitor
00low000000
6-hydroxymethylmexiletinearomatic ether00low000000
4-hydroxymexiletinearomatic ether;
phenols
00low000000
cloquintocet-mexylaromatic ether;
carboxylic ester;
organochlorine compound;
quinolines
00low000000
novaluronaromatic ether;
benzoylurea insecticide;
monochlorobenzenes;
organofluorine compound
00low000000
burseherninaromatic ether;
benzodioxoles;
butan-4-olide;
lignan
plant metabolite00low000000
2,2',4,4'-tetrabromodiphenyl etheraromatic ether;
organobromine compound
00low000000
allocryptopinearomatic ether;
cyclic acetal;
cyclic ketone;
dibenzazecine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound
00low000000
sporidesminaromatic ether;
cyclic ketone;
diketone;
organic disulfide;
organic heteropentacyclic compound;
organochlorine compound;
secondary alcohol;
tertiary alcohol;
tertiary amino compound
mycotoxin;
Wnt signalling activator
00low000000
syringaresinolaromatic ether;
furofuran;
lignan;
polyether;
polyphenol
plant metabolite00low000000
p-methoxy-n-methylphenethylaminearomatic ether;
secondary amino compound
metabolite00low000000
aflatoxin q1aflatoxin;
aromatic ether;
aromatic ketone
carcinogenic agent;
human xenobiotic metabolite
00low000000
u 73122aromatic ether;
aza-steroid;
maleimides
EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor00low000000
cyfluthrinaromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound
agrochemical;
pyrethroid ester insecticide
00low000000
norverapamilaromatic ether;
nitrile;
polyether;
secondary amino compound
00low000000
fumitremorgin aaromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide
mycotoxin00low000000
deguelinaromatic ether;
diether;
organic heteropentacyclic compound;
rotenones
angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor;
plant metabolite
00low000000
aristolochic acid iiaristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound
carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
00low000000
tephrosinaromatic ether;
cyclic ketone;
organic heteropentacyclic compound;
rotenones
antineoplastic agent;
metabolite;
pesticide
00low000000
alpha-hydroxymetoprololaromatic ether00low000000
5-(tetradecyloxy)-2-furancarboxylic acidaromatic ether;
furoic acid
antineoplastic agent;
apoptosis inducer;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
PPARalpha agonist
00low000000
tafenoquine(trifluoromethyl)benzenes;
aminoquinoline;
aromatic ether;
primary amino compound;
secondary amino compound
00low000000
5-hydroxymethylomeprazolearomatic ether;
benzimidazoles;
pyridines;
sulfoxide
drug metabolite00low000000
ym 12617aromatic ether;
secondary amino compound;
sulfonamide
00low000000
cgp 28392aromatic ether00low000000
sodium-binding benzofuran isophthalate1-benzofurans;
aromatic ether;
crown compound;
tetracarboxylic acid
fluorochrome00low000000
garenoxacinaromatic ether;
cyclopropanes;
isoindoles;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic
antibacterial drug;
non-steroidal anti-inflammatory drug
00low000000
ay 25545acetate ester;
aromatic ether;
C-glycosyl compound;
naphthoisochromene;
olefinic compound;
phenols;
tertiary amine
antimicrobial agent;
antineoplastic agent;
bacterial metabolite
00low000000
reboxetinearomatic ether00low000000
b 823-08aromatic ether00low000000
cyclazosinaromatic amide;
aromatic ether;
furans;
monocarboxylic acid amide;
quinazolines;
quinoxaline derivative
adenosine A2A receptor antagonist00low000000
ivabradinearomatic ether;
benzazepine;
carbobicyclic compound;
tertiary amino compound
cardiotonic drug00low000000
febuxostat1,3-thiazolemonocarboxylic acid;
aromatic ether;
nitrile
EC 1.17.3.2 (xanthine oxidase) inhibitor00low000000
marsupsin1-benzofurans;
aromatic ether;
polyphenol
antilipemic drug;
hypoglycemic agent;
metabolite
00low000000
6,6'-bieckolaromatic ether;
oxacycle;
phlorotannin
anti-HIV-1 agent;
metabolite;
radical scavenger
00low000000
xibenololaromatic ether00low000000
cicloprololaromatic ether00low000000
chs 828aromatic ether00low000000
2-(4-methoxyphenoxy)propanoic acidaromatic ether;
carboxylic acid
00low000000
moxifloxacinaromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone
antibacterial drug00low000000
rp 73401aromatic ether;
benzamides;
chloropyridine;
monocarboxylic acid amide
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
phosphodiesterase IV inhibitor
00low000000
2,2',4,4',5,5'-hexabrominated diphenyl etheraromatic ether;
organobromine compound
00low000000
varespladibaromatic ether;
benzenes;
dicarboxylic acid monoamide;
indoles;
monocarboxylic acid;
primary carboxamide
anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor
00low000000
schizandrin baromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin
anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite
00low000000
s 23121aromatic ether;
dicarboximide;
monochlorobenzenes;
monofluorobenzenes;
pyrroline;
terminal acetylenic compound
00low000000
acrovestoneacetophenones;
aromatic ether;
olefinic compound;
polyphenol
antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite
00low000000
corytuberineaporphine alkaloid;
aromatic ether;
organic heterotetracyclic compound;
polyphenol;
tertiary amino compound
plant metabolite00low000000
actinodaphineaporphine alkaloid;
aromatic ether;
organic heteropentacyclic compound;
phenols;
secondary amino compound
antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite;
platelet aggregation inhibitor;
topoisomerase inhibitor
00low000000
isohomovanillic acidaromatic ether;
phenols;
phenylacetic acids
metabolite00low000000
3,5-diiodothyropropionic acidaromatic ether;
monocarboxylic acid;
organoiodine compound;
phenols
00low000000
7,8-dihydro-5,6-dehydrokawain2-pyranones;
aromatic ether
00low000000
4-amino-2-methoxypyrimidineaminopyrimidine;
aromatic ether;
methylcytosine
metabolite00low000000
aristolochic acid Daristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound
carcinogenic agent;
metabolite;
nephrotoxin;
toxin
00low000000
myricanonearomatic ether;
cyclic ketone;
diarylheptanoid;
methoxybenzenes;
phenols
antineoplastic agent;
plant metabolite
00low000000
pannarinaldehyde;
aromatic ether;
depsidones;
organic heterotricyclic compound;
organochlorine compound;
phenols
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lichen metabolite
00low000000
aminopotentidinearomatic ether;
benzamides;
guanidines;
nitrile;
piperidines;
substituted aniline
H2-receptor antagonist00low000000
aristolochic acid caristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound
carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
00low000000
pluviatolidearomatic ether;
benzodioxoles;
butan-4-olide;
lignan;
phenols
plant metabolite00low000000
erysodinearomatic ether;
diether;
Erythrina alkaloid;
organic heterotetracyclic compound;
phenols
antiparasitic agent;
nicotinic antagonist;
phytogenic insecticide
00low000000
erlotinibaromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound
antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor
00low000000
rubrofusarin Baromatic ether;
benzochromenone;
naphtho-gamma-pyrone;
phenols;
polyketide
Aspergillus metabolite00low000000
ly 293111aromatic ether00low000000
enrasentanaromatic ether;
benzodioxoles;
indanes;
monocarboxylic acid;
monomethoxybenzene;
primary alcohol
antihypertensive agent;
endothelin receptor antagonist
00low000000
quizalofoparomatic ether;
monocarboxylic acid;
organochlorine compound;
quinoxaline derivative
00low000000
cyhalofop-butylaromatic ether00low000000
cyperinaromatic ether00low000000
aflatoxin b1aflatoxin;
aromatic ether;
aromatic ketone
carcinogenic agent;
human metabolite
00low000000
etravirineaminopyrimidine;
aromatic ether;
dinitrile;
organobromine compound
antiviral agent;
HIV-1 reverse transcriptase inhibitor
00low000000
5-o-methyllicoricidinaromatic ether;
hydroxyisoflavans;
methoxyisoflavan
antibacterial agent;
plant metabolite
00low000000
pronuciferinearomatic ether;
cyclic ketone;
isoquinoline alkaloid;
isoquinolines;
organic heterotetracyclic compound
plant metabolite00low000000
dronedarone1-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound
anti-arrhythmia drug;
environmental contaminant;
xenobiotic
00low000000
famoxadonearomatic ether;
carbohydrazide;
oxazolidinone
00low000000
cimicoxibaromatic ether;
imidazoles;
organochlorine compound;
organofluorine compound;
sulfonamide
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
00low000000
sorafenib(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
phenylureas;
pyridinecarboxamide
angiogenesis inhibitor;
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
ferroptosis inducer;
tyrosine kinase inhibitor
00low000000
dabuzalgronaromatic ether;
imidazoles;
monochlorobenzenes;
sulfonamide
alpha-adrenergic agonist00low000000
fonsecinaromatic ether;
cyclic hemiketal;
heptaketide;
naphtho-gamma-pyrone;
phenols
Aspergillus metabolite;
marine metabolite
00low000000
lasofoxifenearomatic ether;
N-alkylpyrrolidine;
naphthols;
tetralins
antineoplastic agent;
bone density conservation agent;
cardioprotective agent;
estrogen receptor agonist;
estrogen receptor antagonist
00low000000
(+-)-Dihydromethysticin2-pyranones;
aromatic ether
00low000000
2-[2-[2-(2-aminophenoxy)ethoxy]ethoxy]anilinearomatic ether;
substituted aniline
00low000000
chondocurine (1beta)-(+-)-isomeraromatic ether00low000000
1-methyl-4-prop-2-enoxy-2-pyrimidinonearomatic ether;
pyrimidone
00low000000
noscapinearomatic ether;
benzylisoquinoline alkaloid;
cyclic acetal;
isobenzofuranone;
organic heterobicyclic compound;
organic heterotricyclic compound;
tertiary amino compound
antineoplastic agent;
antitussive;
apoptosis inducer;
plant metabolite
00low000000
4-[4-(3-methyl-4-nitrophenoxy)butoxy]benzonitrilearomatic ether;
C-nitro compound
00low000000
lariciresinolaromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol
antifungal agent;
plant metabolite
00low000000
tryptoquivalinearomatic ether;
indole alkaloid;
organic heteropentacyclic compound
breast cancer resistance protein inhibitor;
mycotoxin
00low000000
2-methoxyestrone17-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols
human metabolite;
mouse metabolite
00low000000
win 54954aromatic ether00low000000
silychristin1-benzofurans;
aromatic ether;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone
lipoxygenase inhibitor;
metabolite;
prostaglandin antagonist;
radical scavenger
00low000000
cleomiscosin aaromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol
anti-inflammatory agent;
metabolite
00low000000
bispyribacaromatic ether;
benzoic acids;
monocarboxylic acid;
pyrimidines
herbicide00low000000
petunidin-3-glucosideanthocyanin cation;
aromatic ether;
beta-D-glucoside
antioxidant;
metabolite
00low000000
malvidin-3-glucosideanthocyanin cation;
aromatic ether;
beta-D-glucoside
metabolite00low000000
dioncophylline caromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthols
antimalarial;
antiplasmodial drug;
metabolite
00low000000
stigmatellinaromatic ether;
chromones;
olefinic compound;
phenols
bacterial metabolite;
quinol oxidation site inhibitor
00low000000
roflumilastaromatic ether;
benzamides;
chloropyridine;
cyclopropanes;
organofluorine compound
anti-asthmatic drug;
phosphodiesterase IV inhibitor
00low000000
teniposidearomatic ether;
beta-D-glucoside;
cyclic acetal;
furonaphthodioxole;
gamma-lactone;
monosaccharide derivative;
phenols;
thiophenes
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
00low000000
prinomastataromatic ether;
hydroxamic acid;
pyridines;
sulfonamide;
thiomorpholines
antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
matrix metalloproteinase inhibitor
00low000000
posaconazolearomatic ether;
conazole antifungal drug;
N-arylpiperazine;
organofluorine compound;
oxolanes;
triazole antifungal drug;
triazoles
trypanocidal drug00low000000
gancaonin I1-benzofurans;
aromatic ether;
resorcinols
antibacterial agent;
plant metabolite
00low000000
glycyrinaromatic ether;
coumarins;
hydroxyisoflavans
antibacterial agent;
metabolite;
plant metabolite
00low000000
glyasperin Daromatic ether;
hydroxyisoflavans;
methoxyisoflavan
plant metabolite00low000000
licoricidinaromatic ether;
hydroxyisoflavans;
methoxyisoflavan
antibacterial agent;
plant metabolite
00low000000
egonol1-benzofurans;
aromatic ether;
benzodioxoles;
primary alcohol
plant metabolite00low000000
N-ethylharminearomatic ether;
beta-carbolines;
semisynthetic derivative
anti-HIV agent00low000000
pf 1163aaromatic ether;
lactam;
macrolide antibiotic;
secondary alcohol
antifungal agent;
Penicillium metabolite
00low000000
pf 1163baromatic ether;
lactam;
macrolide antibiotic
antifungal agent;
Penicillium metabolite
00low000000
licocoumarone1-benzofurans;
aromatic ether;
resorcinols
antibacterial agent;
apoptosis inducer;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite
00low000000
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamidearomatic ether00low000000
LSM-22807aromatic ether00low000000
N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamidearomatic ether00low000000
piperlactam salkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols
anti-inflammatory agent;
antioxidant;
plant metabolite
00low000000
5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-onearomatic ether00low000000
antofinealkaloid antibiotic;
alkaloid;
aromatic ether;
organic heteropentacyclic compound
angiogenesis inhibitor;
anti-inflammatory agent;
antimicrobial agent;
antineoplastic agent;
antiviral agent;
phytotoxin;
plant metabolite
00low000000
xanthohumolaromatic ether;
chalcones;
polyphenol
anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite
00low000000
2-phenoxy-N-(2-pyridinyl)butanamidearomatic ether00low000000
6-amino-4-(2-ethoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrilearomatic ether;
pyranopyrazole
00low000000
N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamidearomatic ether00low000000
2-(3,4-diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazolearomatic ether00low000000
2-[[5-(phenoxymethyl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]acetamidearomatic ether00low000000
1-(8-methyl-2,5,11,14-tetraoxa-8-azabicyclo[13.4.0]nonadeca-1(15),16,18-trien-17-yl)ethanolaromatic ether00low000000
3-[2-(3-phenoxypropyl)-5-tetrazolyl]pyridinearomatic ether00low000000
1-cyclohexyl-5-(2-phenoxyethylthio)tetrazolearomatic ether00low000000
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamidearomatic ether00low000000
6-amino-4-[3-ethoxy-4-[2-(4-morpholinyl)ethoxy]phenyl]-3-ethyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrilearomatic ether;
pyranopyrazole
00low000000
2-[[5-[(2,3-dimethylphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-1-thiophen-2-ylethanonearomatic ether00low000000
(1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanolaromatic ether00low000000
5-(3-butoxyphenyl)-1,3,4-thiadiazol-2-aminearomatic ether00low000000
3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazolearomatic ether00low000000
6-(3,4,5-triethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazolearomatic ether;
triazolothiadiazole
00low000000
4-(1-benzotriazolyl)-5-(2-methoxyphenoxy)benzene-1,2-dicarbonitrilearomatic ether00low000000
4-cyclohexyl-3-[(3-methylphenoxy)methyl]-1H-1,2,4-triazole-5-thionearomatic ether00low000000
7-ethoxy-9-nitro-5H-benzo[b][1,4]benzoxazepin-6-onearomatic ether00low000000
4-[4-(2-quinoxalinyl)phenoxy]benzene-1,2-dicarbonitrilearomatic ether00low000000
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(phenoxymethyl)-4-triazolecarboxylic acid ethyl esteraromatic ether00low000000
2-(4-ethylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamidearomatic ether00low000000
2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamidearomatic ether00low000000
5-[(4-ethylphenoxy)methyl]-N-(2-pyridinylmethyl)-2-furancarboxamidearomatic ether00low000000
7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethionearomatic ether00low000000
N-[4-(4-ethylphenyl)-2-thiazolyl]carbamic acid phenyl esteraromatic ether00low000000
2-(2-bromo-4-methylphenoxy)-N-(2-pyridinylmethyl)acetamidearomatic ether00low000000
1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazinearomatic ether00low000000
2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenolaromatic ether;
C-nitro compound
00low000000
4-[[4-(ethylamino)-6-(methylthio)-1,3,5-triazin-2-yl]oxy]benzoic acid ethyl esteraromatic ether00low000000
5-ethyl-3-[[4-(2-methylpropoxy)phenyl]methylthio]-1H-1,2,4-triazolearomatic ether00low000000
[4-[(2-fluorophenyl)methoxy]phenyl]-(1-pyrrolidinyl)methanethionearomatic ether00low000000
5-[(2-chlorophenoxy)methyl]-3-pyridin-4-yl-1,2,4-oxadiazolearomatic ether00low000000
4-(4-phenylmethoxyphenyl)thiadiazolearomatic ether00low000000
N-methyl-2-[[4-methyl-5-[(4-nitrophenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamidearomatic ether;
C-nitro compound
00low000000
2-[[5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-morpholinyl)ethanonearomatic ether00low000000
4-(3-pyridinyloxy)benzene-1,2-dicarbonitrilearomatic ether00low000000
N-tert-butyl-2-(4-chloro-3-methylphenoxy)acetamidearomatic ether00low000000
1-(2-furanylmethyl)-3-(4-phenoxyphenyl)thioureaaromatic ether00low000000
1-(2-methylpropyl)-3-(4-phenoxyphenyl)thioureaaromatic ether00low000000
1-cyclopentyl-3-(4-phenoxyphenyl)thioureaaromatic ether00low000000
5-[(4-ethoxyphenoxy)methyl]-N-(3-pyridinyl)-2-furancarboxamidearomatic ether00low000000
2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamidearomatic ether00low000000
5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamidearomatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamidearomatic ether00low000000
N-(4,5-dihydrothiazol-2-yl)-2-(2-methylphenoxy)acetamidearomatic ether00low000000
5-(2-fluorophenoxy)-1-methyl-3-nitro-1,2,4-triazolearomatic ether00low000000
1-methyl-5-(1-naphthalenyloxy)-4-nitroimidazolearomatic ether00low000000
curcuminaromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol
anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
00low000000
1-(3,4-dimethoxyphenyl)-3-(2-methoxy-5-nitrophenyl)ureaaromatic ether;
C-nitro compound
00low000000
1-cyclopentyl-3-(2-phenoxyphenyl)thioureaaromatic ether00low000000
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamidearomatic ether;
C-nitro compound
00low000000
2-chloro-12-(4-methoxyphenyl)sulfonylquinoxalino[2,3-b][1,4]benzoxazinearomatic ether00low000000
1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)ureaaromatic ether;
C-nitro compound
00low000000
2-(2-bromo-4-chlorophenoxy)-N-cyclohexyl-N-methylacetamidearomatic ether00low000000
2-furanyl-[4-(4-phenoxyphenyl)sulfonyl-1-piperazinyl]methanonearomatic ether00low000000
4-(2-methoxyphenoxy)-N-(3-pyridinyl)benzenesulfonamidearomatic ether00low000000
1-(3-chlorophenyl)-3-(2-phenoxyphenyl)thioureaaromatic ether00low000000
N-[3-[2-(1-azepanyl)-4,5-dicyanophenoxy]phenyl]acetamidearomatic ether00low000000
2,5-dimethoxy-N-(4-phenoxyphenyl)benzenesulfonamidearomatic ether00low000000
4-[[4-(dimethylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl esteraromatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamidearomatic ether00low000000
1-[4-[[4-(2-chloro-6-nitrophenoxy)phenyl]methoxy]phenyl]ethanonearomatic ether00low000000
N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2,2-dimethylpropanamidearomatic ether00low000000
N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamidearomatic ether00low000000
2-(4-fluorophenoxy)-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)acetamidearomatic ether00low000000
4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-N-propan-2-ylbenzenesulfonamidearomatic ether00low000000
4-(4-tert-butylphenoxy)-5-methoxy-2-phenylpyrimidinearomatic ether00low000000
4-phenoxy-2-phenyl-5-pyrimidinecarboxylic acid ethyl esteraromatic ether00low000000
Src Inhibitor-1aromatic ether;
polyether;
quinazolines;
secondary amino compound
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor00low000000
N-[2,5-dioxo-6-(4-phenoxyphenyl)-3-pyrano[3,2-c]pyridinyl]benzamidearomatic ether00low000000
2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrilearomatic ether00low000000
6-methyl-5-[2-(2-methylphenoxy)ethyl]-2-sulfanylidene-1H-pyrimidin-4-onearomatic ether00low000000
4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanonearomatic ether00low000000
N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diaminearomatic ether00low000000
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thionearomatic ether00low000000
1-[[1-oxo-3-(4-propan-2-yloxyphenyl)propyl]amino]-3-(phenylmethyl)thioureaaromatic ether00low000000
N-[3-(3-methylphenoxy)-5-nitrophenyl]-2-(3-nitro-1,2,4-triazol-1-yl)acetamidearomatic ether00low000000
N-bis(2-fluorophenoxy)phosphoryl-3,4-dimethylanilinearomatic ether00low000000
2-[[4-(2-ethoxyanilino)-6-(4-ethoxyanilino)-2-pyrimidinyl]methylidene]propanedinitrilearomatic ether00low000000
5-methyl-3-[(4-pentoxyphenyl)methylthio]-1H-1,2,4-triazolearomatic ether00low000000
4,5-dichloro-1-[2-(4-chlorophenoxy)ethyl]imidazolearomatic ether00low000000
1-butyl-3-(4-phenoxyphenyl)thioureaaromatic ether00low000000
N-(3-cyano-2-thiophenyl)-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]acetamidearomatic ether00low000000
2-(2-bromophenyl)-5-[(2-chlorophenoxy)methyl]-1,3,4-oxadiazolearomatic ether00low000000
5-(4-ethoxyphenyl)-N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-1,3,4-oxadiazol-2-aminearomatic ether00low000000
4-(4-chloro-2-methylphenoxy)-1-(4-morpholinyl)-1-butanonearomatic ether00low000000
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diaminearomatic ether00low000000
2-[2-(4-chlorophenoxy)ethylthio]pyrimidinearomatic ether00low000000
5-(3-phenoxypropyl)-3-(3-pyridinyl)-1,2,4-oxadiazolearomatic ether00low000000
N-[(3-ethoxy-2-prop-2-enoxyphenyl)methyl]-2-thiazolaminearomatic ether00low000000
2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamidearomatic ether00low000000
4-[2-[(4-chlorophenyl)thio]ethoxy]-3-ethoxybenzaldehydearomatic ether00low000000
1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl esteraromatic ether;
C-nitro compound
00low000000
5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thionearomatic ether00low000000
N-tert-butyl-4-(2-fluorophenoxy)-1-butanaminearomatic ether00low000000
N-butyl-4-phenoxy-1-butanaminearomatic ether00low000000
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) esteraromatic ether00low000000
1,3-dimethyl-5-[[2-[2-(4-nitrophenoxy)ethoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trionearomatic ether;
C-nitro compound
00low000000
4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholinearomatic ether00low000000
2-[2-(3-ethylphenoxy)ethyl]propanedioic acid diethyl esteraromatic ether00low000000
2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] esteraromatic ether00low000000
1-[3-(2-bromo-4-chlorophenoxy)propyl]-4-methylpiperidinearomatic ether00low000000
N4-(2-methoxyphenyl)benzene-1,4-diaminearomatic ether;
substituted aniline
00low000000
4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] esteraromatic ether00low000000
2-phenoxybenzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] esteraromatic ether00low000000
1-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-[4-(1,3,4-oxadiazol-2-yl)phenoxy]ethanonearomatic ether00low000000
N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-2-(2-methylphenoxy)-N-(2-methylpropyl)acetamidearomatic ether00low000000
4-[[6-[(2-methyl-5-thieno[2,3-e][1,3]benzothiazolyl)oxy]-3-pyridinyl]sulfonyl]morpholinearomatic ether00low000000
5-(3-fluorophenoxy)-8-nitroisoquinolinearomatic ether00low000000
1-[4-(2-prop-2-enylphenoxy)butyl]pyrrolidinearomatic ether00low000000
2-(2,4-dibromophenoxy)-N-[oxo-(propan-2-ylamino)methyl]acetamidearomatic ether00low000000
4-phenoxyphenyl 4-hydroxypiperidine-1-carboxylatearomatic ether00low000000
N'-benzoyl-5-(3,5-dichlorophenoxy)-2-furancarbohydrazidearomatic ether00low000000
1-[2-[(4-chlorophenoxy)methyl]-4-thiazolyl]ethanonearomatic ether00low000000
5-(benzyloxy)-2-(hydroxymethyl)-1,4-dihydropyridin-4-onearomatic ether00low000000
2-(4-aminophenoxy)isophthalonitrilearomatic ether00low000000
N5-(2-chloro-6-phenoxybenzyl)-1H-1,2,4-triazole-3,5-diaminearomatic ether00low000000
N-[(2-chloro-6-phenoxyphenyl)methyl]benzenesulfonamidearomatic ether00low000000
N-[5-(tert-butyl)-3-isoxazolyl]-N'-[2-(trifluoromethoxy)phenyl]ureaaromatic ether00low000000
6-(4-methoxyphenoxy)-2-imidazo[1,2-b]pyridazinecarboxylic acid ethyl esteraromatic ether00low000000
2-fluoro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamidearomatic ether;
C-nitro compound
00low000000
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrilearomatic ether;
C-nitro compound
00low000000
2,4-dichloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamidearomatic ether;
C-nitro compound
00low000000
1-anilino-3-[4-(3-anilino-2-hydroxypropoxy)phenoxy]-2-propanolaromatic ether00low000000
1-[4-(3-ethoxyphenoxy)butyl]imidazolearomatic ether00low000000
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-oxolanecarboxamidearomatic ether00low000000
1-[[2-(2,4-difluorophenoxy)-1-oxopropyl]amino]-3-(2-oxolanylmethyl)thioureaaromatic ether00low000000
N-[[(5-bromo-6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-(2-chlorophenoxy)acetamidearomatic ether00low000000
2-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-methoxy-2-nitrophenyl)acetamidearomatic ether;
C-nitro compound
00low000000
4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxidearomatic ether00low000000
1-(2-fluorophenyl)-3-(4-methoxy-2-nitrophenyl)ureaaromatic ether;
C-nitro compound
00low000000
2-[[5-[(2-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamidearomatic ether00low000000
cyclopropanecarboxylic acid [2-oxo-2-(4-phenoxyanilino)ethyl] esteraromatic ether00low000000
toremifenearomatic ether;
organochlorine compound;
tertiary amine
antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
00low000000
dieckolaromatic ether;
oxacycle;
phlorotannin
anticoagulant;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
metabolite;
radical scavenger
00low000000
2-[(2-ethoxyphenoxy)-phenylmethyl]morpholinearomatic ether00low000000
naproxolaromatic etherantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
tamoxifen n-oxidearomatic ether;
tertiary amine oxide
anti-estrogen;
metabolite
00low000000
diafenthiuronaromatic ether;
thiourea acaricide;
thiourea insecticide
oxidative phosphorylation inhibitor;
proinsecticide
00low000000
ospemifenearomatic ether;
organochlorine compound;
primary alcohol
anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator
00low000000
tandutinibaromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
piperidines;
quinazolines;
tertiary amino compound
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
zd 6474aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
adefoviraromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol
antimalarial;
Aspergillus metabolite;
marine metabolite
00low000000
3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamidearomatic ether;
C-nitro compound
00low000000
N-(2-hydroxyethyl)-4-[2-nitro-4-(trifluoromethyl)phenoxy]benzamidearomatic ether00low000000
N'-[2-[(4-amino-5-cyano-2-pyrimidinyl)thio]-1-oxoethyl]-2-(4-methylphenoxy)acetohydrazidearomatic ether00low000000
N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamidearomatic ether00low000000
6-amino-4-(2-ethoxy-4-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrilearomatic ether;
pyranopyrazole
00low000000
1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylureaaromatic ether00low000000
quinoxyfenaromatic ether;
monofluorobenzenes;
organochlorine compound;
quinolines
antifungal agrochemical00low000000
nafadotridearomatic ether;
naphthalenecarboxamide;
nitrile;
pyrrolidines;
tertiary amino compound
dopaminergic antagonist00low000000
1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]ureaaromatic ether;
C-nitro compound
00low000000
2-methyl-1,3-bis(phenylmethoxy)benzenearomatic ether00low000000
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)ureaaromatic ether00low000000
3-[(4-ethylphenoxy)methyl]-4-(6-methylheptan-2-yl)-1H-1,2,4-triazole-5-thionearomatic ether00low000000
2-chloro-N-(2-methyl-6-oxo-5H-benzo[b][1,4]benzoxazepin-8-yl)acetamidearomatic ether00low000000
5-(benzenesulfonyl)-4-(2,6-dimethylphenoxy)-2-phenylpyrimidinearomatic ether00low000000
4-(2-methylphenoxy)-6-phenylfuro[2,3-d]pyrimidinearomatic ether00low000000
1-[4-(2-chlorophenoxy)butyl]imidazolearomatic ether;
imidazoles;
monochlorobenzenes
00low000000
N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamidearomatic ether;
C-nitro compound
00low000000
N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamidearomatic ether;
C-nitro compound
00low000000
N-[4-(phenoxymethyl)-2-thiazolyl]-1-adamantanecarboxamidearomatic ether00low000000
hydroxypioglitazonearomatic ether;
pyridines;
thiazolidinediones
human xenobiotic metabolite00low000000
sc 560aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles
angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug
00low000000
sc-19220aromatic ether00low000000
5-methyl-4-(3-phenoxyphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-6-carboxylic acid ethyl esteraromatic ether00low000000
8-[4-(4-fluorophenoxy)-3-nitrophenyl]-7-(2-hydroxyethyl)-3-(phenylmethyl)purine-2,6-dionearomatic ether00low000000
2-phenoxybenzoic acid [2-oxo-2-(propan-2-ylamino)ethyl] esteraromatic ether00low000000
2-(4-bromophenoxy)-N'-[2-[(4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]acetohydrazidearomatic ether00low000000
2-(2-methoxyanilino)-2-(2-phenylmethoxyphenyl)acetonitrilearomatic ether;
substituted aniline
00low000000
N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamidearomatic ether00low000000
5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-olaromatic ether00low000000
3,3-dimethyl-1,5-dinitro-6-phenoxy-3-azoniabicyclo[3.3.1]non-6-enearomatic ether00low000000
fraxinaromatic ether;
beta-D-glucoside;
hydroxycoumarin
anti-inflammatory agent;
hepatoprotective agent;
plant metabolite
00low000000
fraxetinaromatic ether;
hydroxycoumarin
anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent
00low000000
5,6-dehydrokawain2-pyranones;
aromatic ether
00low000000
jtk-303aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone
HIV-1 integrase inhibitor00low000000
coniferinaromatic ether;
cinnamyl alcohol beta-D-glucoside;
monosaccharide derivative
plant metabolite00low000000
daphnoretinaromatic ether;
hydroxycoumarin
antineoplastic agent;
antiviral agent;
metabolite
00low000000
kavain2-pyranones;
aromatic ether
00low000000
methysticin2-pyranones;
aromatic ether
00low000000
yangonin2-pyranones;
aromatic ether
00low000000
hinokiflavonearomatic ether;
biflavonoid;
hydroxyflavone
antineoplastic agent;
metabolite;
neuroprotective agent
00low000000
gentiacauleinaromatic ether;
polyphenol;
xanthones
plant metabolite00low000000
gentisinaromatic ether;
polyphenol;
xanthones
plant metabolite00low000000
isogentisinaromatic ether;
polyphenol;
xanthones
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite
00low000000
mangostinaromatic ether;
phenols;
xanthones
antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite
00low000000
1,8-dihydroxy-3,7-dimethoxyxanthonearomatic ether;
polyphenol;
xanthones
plant metabolite00low000000
swerchirinaromatic ether;
phenols;
xanthones
hypoglycemic agent;
metabolite
00low000000
1,2,8-trihydroxy-6-methoxyxanthonearomatic ether;
polyphenol;
xanthones
antioxidant;
plant metabolite
00low000000
wedelolactonearomatic ether;
coumestans;
delta-lactone;
polyphenol
antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite
00low000000
cyhalothrinaromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound
agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
00low000000
sofalconearomatic ether;
chalcones;
monocarboxylic acid
anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite
00low000000
neticonazolearomatic ether;
benzenes;
conazole antifungal drug;
enamine;
imidazole antifungal drug;
imidazoles;
methyl sulfide
antifungal drug;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
00low000000
pibutidinearomatic ether;
cyclobutenones;
olefinic compound;
piperidines;
primary amino compound;
pyridines;
secondary amino compound
anti-ulcer drug;
H2-receptor antagonist
00low000000
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrilearomatic ether00low000000
ro 41-5253aromatic ether;
benzoic acids;
sulfone;
thiochromane
apoptosis inducer;
retinoic acid receptor alpha antagonist
00low000000
glycycoumarinaromatic ether;
coumarins;
resorcinols
antispasmodic drug;
plant metabolite
00low000000
isoginkgetinaromatic ether;
biflavonoid
antineoplastic agent;
EC 3.4.24.35 (gelatinase B) inhibitor;
plant metabolite
00low000000
neoglycyrolaromatic ether;
coumestans;
delta-lactone;
polyphenol
antineoplastic agent;
plant metabolite
00low000000
rhamnazinaromatic ether;
dimethoxyflavone;
phenols;
trihydroxyflavone
antineoplastic agent;
plant metabolite
00low000000
bosutinibaminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
bw b70caromatic ether;
hydroxamic acid;
organofluorine compound;
ureas
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor00low000000
lichexanthonearomatic ether;
phenols;
xanthones
plant metabolite00low000000
alternariol monomethyl etheraromatic ether;
benzochromenone
antifungal agent;
fungal metabolite;
mycotoxin
00low000000
decussatinaromatic ether;
phenols;
xanthones
plant metabolite00low000000
bedaquilinearomatic ether;
naphthalenes;
organobromine compound;
quinolines;
tertiary alcohol;
tertiary amino compound
antitubercular agent;
ATP synthase inhibitor
00low000000
dimethomorpharomatic ether;
enamide;
monochlorobenzenes;
morpholine fungicide;
tertiary carboxamide
00low000000
benanomicin baromatic ether;
disaccharide derivative;
L-alanine derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol
00low000000
pradimicin baromatic ether;
L-alanine derivative;
monosaccharide derivative;
polyketide;
polyphenol;
pradimicin;
secondary alcohol
00low000000
1,7-dihydroxy-4-methoxyxanthonearomatic ether;
phenols;
xanthones
metabolite;
plant metabolite
00low000000
pradimicin aaromatic ether;
carboxylic acid;
disaccharide derivative;
L-alanine derivative;
p-quinones;
polyphenol;
pradimicin;
secondary alcohol
00low000000
clodinafoparomatic ether;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
pyridines
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
phenoxy herbicide
00low000000
ici 118551aromatic ether;
indanes;
secondary alcohol;
secondary amino compound
beta-adrenergic antagonist00low000000
ochnaflavonearomatic ether;
biflavonoid;
hydroxyflavone
anti-inflammatory agent;
antiatherogenic agent;
antibacterial agent;
EC 3.1.1.4 (phospholipase A2) inhibitor;
leukotriene antagonist;
plant metabolite
00low000000
3-(4-fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene 1-oxidearomatic ether00low000000
flavasperonearomatic ether;
naphtho-gamma-pyrone;
phenols
acyl-CoA:cholesterol acyltransferase 2 inhibitor;
antiviral agent;
Aspergillus metabolite;
marine metabolite
00low000000
4-hydroxycordoinaromatic ether;
chalcones;
polyphenol
anti-inflammatory agent;
antibacterial agent;
plant metabolite
00low000000
n-feruloylserotoninaromatic ether;
cinnamamides;
hydroxyindoles;
phenols;
secondary carboxamide
plant metabolite00low000000
tyrphostin ag825aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide
epidermal growth factor receptor antagonist00low000000
kresoxim-methylaromatic ether;
methoxyiminoacetate strobilurin antifungal agent;
methyl ester;
oxime O-ether
antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
00low000000
5-methoxy-3,6-diphenyl-1,2,4-triazinearomatic ether00low000000
pyrachlostrobinaromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles
antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic
00low000000
piericidin aaromatic ether;
methylpyridines;
monohydroxypyridine;
secondary allylic alcohol
antimicrobial agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor;
mitochondrial respiratory-chain inhibitor
00low000000
metrafenonearomatic ether;
aryl phenyl ketone fungicide;
benzophenones;
organobromine compound
antifungal agrochemical00low000000
2-(4-fluoro-3-(trifluoromethyl)phenoxy)-n-(phenylmethyl)butanamide(trifluoromethyl)benzenes;
aromatic ether;
monocarboxylic acid amide;
monofluorobenzenes
00low000000
b 43aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector
00low000000
5-(4-phenylbutoxy)psoralenaromatic ether;
benzenes;
psoralens
geroprotector;
immunosuppressive agent;
potassium channel blocker
00low000000
5-ia-85380aromatic ether00low000000
yunaconitineacetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound
antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic
00low000000
ru 5866817beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
organofluorine compound;
sulfone
anti-estrogen;
antineoplastic agent;
estrogen receptor antagonist
00low000000
altenusinaromatic ether;
carboxybiphenyl;
catechols;
hydroxybiphenyls;
polyphenol
antifungal agent;
fungal metabolite
00low000000
gw 5015161,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound
carcinogenic agent;
PPARbeta/delta agonist
00low000000
bay 58-2667aromatic ether;
benzoic acids;
dicarboxylic acid;
tertiary amino compound
antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent
00low000000
camostataromatic ether;
phenols
00low000000
lenvatinibaromatic amide;
aromatic ether;
cyclopropanes;
monocarboxylic acid amide;
monochlorobenzenes;
phenylureas;
quinolines
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist;
orphan drug;
vascular endothelial growth factor receptor antagonist
00low000000
nsc 716970aromatic amine;
aromatic ether;
indolecarboxamide;
organochlorine compound
antineoplastic agent00low000000
lobeglitazonearomatic ether00low000000
noviflumuronaromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound
00low000000
etomoxiraromatic ether00low000000
fr 148083aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone
antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor
00low000000
9-methoxycanthin-6-onearomatic ether;
indole alkaloid;
organic heterotetracyclic compound
antineoplastic agent;
antiplasmodial drug;
metabolite
00low000000
sb 3ct compoundaromatic ether00low000000
varespladib methylaromatic ether;
benzenes;
indoles;
methyl ester;
primary carboxamide
anti-inflammatory drug;
antidote;
EC 3.1.1.4 (phospholipase A2) inhibitor;
prodrug
00low000000
dapagliflozinaromatic ether;
C-glycosyl compound;
monochlorobenzenes
hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
00low000000
naveglitazararomatic ether00low000000
tivozanibaromatic ether00low000000
ustiloxin baromatic ether;
heterodetic cyclic peptide;
macrocycle;
phenols;
secondary alcohol;
secondary carboxamide;
sulfoxide
Aspergillus metabolite;
microtubule-destabilising agent;
mycotoxin
00low000000
hypothemycinaromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone
antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite
00low000000
tryprostatin aaromatic ether;
dipeptide;
indole alkaloid;
indoles;
pyrrolopyrazine
breast cancer resistance protein inhibitor00low000000
cediranibaromatic ether00low000000
3-iodothyronaminearomatic ether00low000000
n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloridearomatic ether;
hydrochloride;
methoxybenzenes;
tertiary amino compound
antipsychotic agent;
receptor modulator
00low000000
rubraxanthonearomatic ether;
polyphenol;
xanthones
antibacterial agent;
antineoplastic agent;
metabolite
00low000000
7,8-Dihydroyangonin2-pyranones;
aromatic ether
00low000000
sch 51344aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound
antineoplastic agent00low000000
ancistroealaine aaromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes
antileishmanial agent;
antiplasmodial drug;
metabolite;
trypanocidal drug
00low000000
pimavanserinaromatic ether;
monofluorobenzenes;
piperidines;
tertiary amino compound;
ureas
5-hydroxytryptamine 2A receptor inverse agonist;
antipsychotic agent;
serotonergic antagonist
00low000000
tolfenpyradaromatic amide;
aromatic ether;
organochlorine compound;
pyrazole insecticide
agrochemical;
antifungal agent;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor
00low000000
SIS3 free basearomatic ether;
enamide;
isoquinolines;
monocarboxylic acid amide;
pyrrolopyridine;
tertiary carboxamide
Smad3 inhibitor00low000000
apixabanaromatic ether;
lactam;
piperidones;
pyrazolopyridine
anticoagulant;
EC 3.4.21.6 (coagulation factor Xa) inhibitor
00low000000
bibw 2992aromatic ether;
enamide;
furans;
monochlorobenzenes;
organofluorine compound;
quinazolines;
secondary carboxamide;
tertiary amino compound
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
dihydrokavain2-pyranones;
aromatic ether
00low000000
troglitazone sulfatearomatic ether;
thiazolidinone
00low000000
arisugacinaromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol
antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite
00low000000
saracatinibaromatic ether;
benzodioxoles;
diether;
N-methylpiperazine;
organochlorine compound;
oxanes;
quinazolines;
secondary amino compound
anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
radiosensitizing agent
00low000000
fonsecinone aaromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol
antibacterial agent;
Aspergillus metabolite
00low000000
crenolanibaminopiperidine;
aromatic ether;
benzimidazoles;
oxetanes;
quinolines;
tertiary amino compound
angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
aiphanolaromatic ether;
benzodioxine;
lignan;
stilbenoid
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor00low000000
nigerloxinaromatic ether;
benzamides;
benzoic acids;
phenols;
styrenes
antioxidant;
Aspergillus metabolite;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
radical scavenger
00low000000
msdc-0160aromatic ether00low000000
dihydroxanthohumolaromatic ether;
dihydrochalcones;
polyphenol
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite
00low000000
PB28aromatic ether;
piperazines;
tetralins
anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist
00low000000
7-phloroeckolaromatic ether;
phlorotannin
antioxidant;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
metabolite
00low000000
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranosidearomatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol
antineoplastic agent;
metabolite
00low000000
PDGF receptor tyrosine kinase inhibitor IIIaromatic ether;
N-arylpiperazine;
N-carbamoylpiperazine;
phenylureas;
quinazolines;
tertiary amino compound
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor00low000000
fluoxastrobinaromatic ether;
dioxazine;
monochlorobenzenes;
organofluorine compound;
oxime O-ether;
pyrimidines;
strobilurin antifungal agent
antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
00low000000
regorafenib(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide
antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor
00low000000
erastinaromatic ether;
diether;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
quinazolines;
tertiary carboxamide
antineoplastic agent;
ferroptosis inducer;
voltage-dependent anion channel inhibitor
00low000000
brivanibaromatic ether;
diether;
fluoroindole;
pyrrolotriazine;
secondary alcohol
angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
drug metabolite;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist
00low000000
fg-4592aromatic ether;
isoquinolines;
N-acylglycine
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
00low000000
picoxystrobinaromatic ether;
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
organofluorine compound;
pyridines
antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor
00low000000
cenicrivirocaromatic ether;
benzazocine;
diether;
imidazoles;
secondary carboxamide;
sulfoxide
anti-HIV agent;
anti-inflammatory agent;
antirheumatic drug;
chemokine receptor 2 antagonist;
chemokine receptor 5 antagonist
00low000000
mandipropamidaromatic ether;
monocarboxylic acid amide;
monochlorobenzenes;
terminal acetylenic compound
00low000000
glyceryl ferulate1-monoglyceride;
aromatic ether;
enoate ester;
phenols
antioxidant;
plant metabolite;
ultraviolet filter
00low000000
ki 8751aromatic ether00low000000
ceratamine aalkaloid;
aromatic ether;
cyclic ketone;
organic heterobicyclic compound;
organobromine compound;
secondary amino compound;
tertiary amine
antimitotic;
metabolite
00low000000
azd 8931aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
tertiary amino compound
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist
00low000000
bay94 9172(18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline
radioactive imaging agent00low000000
olodaterolaromatic ether;
benzoxazine;
phenols;
secondary alcohol;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent
00low000000
dorsomorphinaromatic ether;
piperidines;
pyrazolopyrimidine;
pyridines
bone morphogenetic protein receptor antagonist;
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
00low000000
cj-042794aromatic ether00low000000
hu 308aromatic ether;
bridged compound;
carbobicyclic compound;
primary allylic alcohol;
synthetic cannabinoid
anti-inflammatory agent;
antihypertensive agent;
apoptosis inhibitor;
bone density conservation agent;
CB2 receptor agonist
00low000000
ki11502aromatic ether;
benzamides;
quinolines;
thioureas
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
apremilastaromatic ether;
N-acetylarylamine;
phthalimides;
sulfone
non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor
00low000000
PF-00835231aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide
anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
00low000000
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amineaminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate
antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
chir-265aromatic ether00low000000
aminocandinaromatic ether;
echinocandin;
homodetic cyclic peptide
antiinfective agent00low000000
zk 756326aromatic ether00low000000
bay 60-6583aminopyridine;
aromatic ether;
aryl sulfide;
cyanopyridine;
cyclopropanes;
monocarboxylic acid amide
adenosine A2B receptor agonist;
anti-inflammatory agent;
cardioprotective agent
00low000000
empagliflozinaromatic ether;
C-glycosyl compound;
monochlorobenzenes;
tetrahydrofuryl ether
hypoglycemic agent;
sodium-glucose transport protein subtype 2 inhibitor
00low000000
4-[5-(4-ethoxyphenyl)-3-isoxazolyl]-N-[(4-methylphenyl)methyl]butanamidearomatic ether00low000000
bgt226aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines
antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
00low000000
n-desmethylrosiglitazonearomatic ether00low000000
4-(5-methyl-3-nitro-1-pyrazolyl)-N-[3-(4-methylphenoxy)-5-nitrophenyl]butanamidearomatic ether00low000000
verruculogenaromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide
Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker
00low000000
1-O-feruloyl-beta-D-glucosearomatic ether;
beta-D-glucoside;
cinnamate ester;
phenols
antioxidant;
plant metabolite
00low000000
2,2',4,5'-tetrabromodiphenyl etheraromatic ether;
organobromine compound
00low000000
hexabromodiphenyl ether 154aromatic ether;
organobromine compound
00low000000
bde 183aromatic ether;
organobromine compound
00low000000
l-798106aromatic ether;
bromobenzenes;
N-sulfonylcarboxamide
prostaglandin receptor antagonist00low000000
aflatoxin m1aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol
Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite
00low000000
macitentanaromatic ether;
organobromine compound;
pyrimidines;
ring assembly;
sulfamides
antihypertensive agent;
endothelin receptor antagonist;
orphan drug
00low000000
CDN1163aromatic ether;
quinolines;
secondary carboxamide
SERCA activator00low000000
e 7050aromatic ether00low000000
N-[(5-chloro-2-thiophenyl)methyl]-5-[(2,6-difluorophenoxy)methyl]-3-isoxazolecarboxamidearomatic ether00low000000
dafadine Caromatic amide;
aromatic ether;
difluorobenzene;
isoxazoles;
N-acylpiperidine;
pyridines
P450 inhibitor00low000000
dafadine Baromatic amide;
aromatic ether;
isoxazoles;
monochlorobenzenes;
monofluorobenzenes;
N-acylpiperidine;
pyridines
P450 inhibitor00low000000
3-[5-(5-methyl-2-thiophenyl)-1,3,4-oxadiazol-2-yl]-N-[2-(3-pyridinyloxy)propyl]propanamidearomatic ether00low000000
violaceol IIaromatic ether;
catechols;
resorcinols
mycotoxin00low000000
pamapimodaromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound
antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
gsk6906931,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
00low000000
cnf 20242-aminopurines;
aromatic ether;
organochlorine compound;
pyridines
antineoplastic agent;
Hsp90 inhibitor
00low000000
uk 453,061aromatic ether00low000000
8-{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl}-5,7-dimethoxy-4-pentyl-2H-chromen-2-onearomatic ether;
coumarins;
pyrrolidines;
tertiary amino compound
00low000000
zm323881aromatic ether;
benzyl ether;
fluorophenol;
halophenol;
monofluorobenzenes;
organic cation;
quinazolines;
secondary amino compound;
substituted aniline
vascular endothelial growth factor receptor antagonist00low000000
compound waromatic ether00low000000
2-[[4-[2-[(2-methylpropan-2-yl)oxy]anilino]-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanolaromatic ether00low000000
interiotherin baromatic ether;
fatty acid ester;
lignan;
organic heteropentacyclic compound;
oxacycle
anti-HIV agent;
metabolite
00low000000
5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-onearomatic ether;
homoisoflavonoid;
polyphenol
angiogenesis modulating agent;
plant metabolite
00low000000
ph 797804aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone
anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
diorcinolaromatic ether;
phenols
fungal metabolite;
marine metabolite;
metabolite
00low000000
2-[[4-(2-phenoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanolaromatic ether00low000000
2-[[4-(1-pyrrolidinyl)-6-[2-(trifluoromethoxy)anilino]-1,3,5-triazin-2-yl]amino]ethanolaromatic ether00low000000
2-[[4-(5-chloro-2-ethoxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanolaromatic ether00low000000
2-[[4-(5-chloro-2-propan-2-yloxyanilino)-6-(1-pyrrolidinyl)-1,3,5-triazin-2-yl]amino]ethanolaromatic ether00low000000
mk 5108aromatic ether00low000000
1-azepanyl-[5-[(4-chloro-3,5-dimethylphenoxy)methyl]-3-isoxazolyl]methanonearomatic ether00low000000
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridinearomatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines
geroprotector;
P450 inhibitor
00low000000
dafadine Daromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
organofluorine compound;
pyridines
P450 inhibitor00low000000
1-[(1-ethyl-3-methyl-4-pyrazolyl)methyl]-N-[4-(2-fluorophenoxy)phenyl]-4-piperidinecarboxamidearomatic ether00low000000
dafadine Oaromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines;
ring assembly
P450 inhibitor00low000000
5-[(3,4-dimethylphenoxy)methyl]-N-methyl-N-(4-oxanylmethyl)-3-isoxazolecarboxamidearomatic ether00low000000
pci 32765acrylamides;
aromatic amine;
aromatic ether;
N-acylpiperidine;
pyrazolopyrimidine;
tertiary carboxamide
antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
00low000000
florbetapir f 18(18)F radiopharmaceutical;
aromatic ether;
organofluorine compound;
pyridines;
substituted aniline
radioactive imaging agent00low000000
AMG-208aromatic ether;
quinolines;
triazolopyridazine
antineoplastic agent;
c-Met tyrosine kinase inhibitor
00low000000
6-methoxyspirotryprostatin baromatic ether;
azaspiro compound;
indole alkaloid;
indolones
antineoplastic agent;
Aspergillus metabolite
00low000000
lucitanibaromatic ether;
cyclopropanes;
naphthalenecarboxamide;
primary amino compound;
quinolines
antineoplastic agent;
fibroblast growth factor receptor antagonist;
vascular endothelial growth factor receptor antagonist
00low000000
act-132577aromatic ether;
organobromine compound;
pyrimidines;
sulfamides
antihypertensive agent;
drug metabolite;
endothelin receptor antagonist;
xenobiotic metabolite
00low000000
cabozantinibaromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
poziotinibacrylamides;
aromatic ether;
dichlorobenzene;
diether;
monofluorobenzenes;
N-acylpiperidine;
quinazolines;
secondary amino compound;
substituted aniline
antineoplastic agent;
apoptosis inducer;
epidermal growth factor receptor antagonist
00low000000
gsk 2126458aromatic ether;
difluorobenzene;
pyridazines;
pyridines;
quinolines;
sulfonamide
anticoronaviral agent;
antineoplastic agent;
autophagy inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor;
radiosensitizing agent
00low000000
gsk 1363089aromatic ether00low000000
1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-propan-2-ylureaaromatic ether00low000000
1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(methylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-propan-2-ylureaaromatic ether00low000000
3-cyclohexyl-1-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylureaaromatic ether00low000000
3-cyclohexyl-1-[[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-10-[[oxo-(propan-2-ylamino)methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methylureaaromatic ether00low000000
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-pyridinecarboxamidearomatic ether00low000000
1-(3,5-dimethyl-4-isoxazolyl)-3-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]ureaaromatic ether00low000000
monepantel(trifluoromethyl)benzenes;
aromatic ether;
aryl sulfide;
nitrile;
secondary carboxamide
anthelminthic drug;
nematicide
00low000000
an2728aromatic ether;
benzoxaborole;
nitrile
antipsoriatic;
non-steroidal anti-inflammatory drug;
phosphodiesterase IV inhibitor
00low000000
grazopreviraromatic ether;
azamacrocycle;
carbamate ester;
cyclopropanes;
lactam;
N-sulfonylcarboxamide;
quinoxaline derivative
antiviral drug;
hepatitis C protease inhibitor;
hepatoprotective agent
00low000000
hordatine aaromatic ether;
benzofurans;
dicarboxylic acid diamide;
guanidines;
phenols
adrenergic antagonist;
metabolite
00low000000
kavain2-pyranones;
aromatic ether
00low000000
5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinonearomatic ether00low000000
tak-632(trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide
antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor
00low000000
lrrk2-in1aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
00low000000
quinolobactinaromatic ether;
monohydroxyquinoline;
phenols;
quinolinemonocarboxylic acid
bacterial metabolite;
siderophore
00low000000
AZD1979aromatic ether;
azaspiro compound;
carboxamide;
N-acylazetidine;
oxadiazole;
oxaspiro compound;
oxetanes
melanin-concentrating hormone receptor antagonist00low000000
ML240aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound
antineoplastic agent00low000000
aripiprazole lauroxilaromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone
H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist
00low000000
abt-199aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
00low000000
xl765aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide
antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
00low000000
DMH1aromatic ether;
pyrazolopyrimidine;
quinolines
antineoplastic agent;
bone morphogenetic protein receptor antagonist;
protein kinase inhibitor
00low000000
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamidearomatic ether;
methylpyridines;
olefinic compound;
quinazolines;
secondary amino compound;
secondary carboxamide;
toluenes
00low000000
pf 4800567aromatic ether;
monochlorobenzenes;
oxanes;
pyrazolopyrimidine
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor00low000000
propenylphosphonic acidaromatic ether00low000000
abt-333aromatic ether;
naphthalenes;
pyrimidone;
sulfonamide
antiviral drug;
nonnucleoside hepatitis C virus polymerase inhibitor
00low000000
naloxegolaromatic ether;
organic heteropentacyclic compound;
phenols;
polyether;
tertiary alcohol
cathartic;
mu-opioid receptor antagonist
00low000000
ceritinibaminopyrimidine;
aromatic ether;
organochlorine compound;
piperidines;
secondary amino compound;
sulfone
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
MK-8353aromatic ether;
dihydropyridine;
indazoles;
methyl sulfide;
N-alkylpyrrolidine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
triazoles
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
N-[(5-methyl-2-furanyl)methylideneamino]-2-phenoxybenzamidearomatic ether00low000000
saroglitazararomatic ether;
methyl sulfide;
monocarboxylic acid;
pyrroles
hypoglycemic agent;
PPARalpha agonist;
PPARgamma agonist
00low000000
fertaric acidaromatic ether;
cinnamate ester;
dicarboxylic acid;
phenols;
tetraric acid derivative
00low000000
2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
tertiary alcohol;
triazoles
00low000000
pf-06463922aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
DDR1-IN-1(trifluoromethyl)benzenes;
aromatic ether;
benzamides;
N-alkylpiperazine;
oxindoles;
secondary carboxamide
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor00low000000
ldc4297aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
00low000000
ap20187aromatic ether;
carboxylic ester;
N-acylpiperidine;
tertiary amino compound
ligand00low000000
methysticin2-pyranones;
aromatic ether
00low000000
biliatresonearomatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols
plant metabolite;
toxin
00low000000
tak 4911,2,4-oxadiazole;
aromatic ether;
benzimidazoles;
carboxylic ester;
cyclic carbonate ester;
dioxolane
angiotensin receptor antagonist;
antihypertensive agent;
prodrug
00low000000
azilsartan1,2,4-oxadiazole;
aromatic ether;
benzimidazolecarboxylic acid
angiotensin receptor antagonist;
antihypertensive agent
00low000000
hydrazinocurcuminaromatic ether;
olefinic compound;
polyphenol;
pyrazoles
angiogenesis modulating agent;
antineoplastic agent;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
00low000000
mirodenafilaromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide
EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
00low000000
cerulomycinaldoxime;
aromatic ether;
bipyridines;
pyridine alkaloid
antineoplastic agent;
bacterial metabolite;
marine metabolite
00low000000
undecylprodigiosinalkaloid;
aromatic ether;
tripyrrole
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent
00low000000
sb-590885aromatic ether;
imidazoles;
ketoxime;
pyridines;
tertiary amino compound
00low000000
2-[[4-(trifluoromethoxy)phenyl]methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-onearomatic ether00low000000
PF-07304814aromatic ether;
indolecarboxamide;
L-leucine derivative;
phosphate monoester;
pyrrolidin-2-ones;
secondary carboxamide
anticoronaviral agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
prodrug
00low000000
bupropionaromatic ketone;
monochlorobenzenes;
secondary amino compound
antidepressant;
environmental contaminant;
xenobiotic
00low000000
sk&f-38393benzazepine;
catechols;
secondary amino compound
00low000000
monomethylpropionaromatic ketone;
secondary amino compound
00low000000
acebutololaromatic amide;
ethanolamines;
ether;
monocarboxylic acid amide;
propanolamine;
secondary amino compound
anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympathomimetic agent
00low000000
albuterolphenols;
phenylethanolamines;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
00low000000
alminoprofenamino acid;
monocarboxylic acid;
secondary amino compound;
substituted aniline
antipyretic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
alprenololsecondary alcohol;
secondary amino compound
anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
sympatholytic agent
00low000000
amodiaquineaminoquinoline;
organochlorine compound;
phenols;
secondary amino compound;
tertiary amino compound
anticoronaviral agent;
antimalarial;
drug allergen;
EC 2.1.1.8 (histamine N-methyltransferase) inhibitor;
non-steroidal anti-inflammatory drug;
prodrug
00low000000
benzylhydrochlorothiazidebenzenes;
benzothiadiazine;
organochlorine compound;
secondary amino compound;
sulfonamide
00low000000
betahistineaminoalkylpyridine;
secondary amino compound
H1-receptor agonist;
vasodilator agent
00low000000
carvedilolcarbazoles;
secondary alcohol;
secondary amino compound
alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent
00low000000
chloroquineaminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound
anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
00low000000
clenbuterolamino alcohol;
dichlorobenzene;
ethanolamines;
primary arylamine;
secondary amino compound;
substituted aniline
beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
00low000000
clorprenalineethanolamines;
monochlorobenzenes;
secondary amino compound
00low000000
desipraminedibenzoazepine;
secondary amino compound
adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
00low000000
diclofenacamino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound
antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
00low000000
fenfluramine(trifluoromethyl)benzenes;
secondary amino compound
appetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
00low000000
berotekresorcinols;
secondary alcohol;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent;
tocolytic agent
00low000000
formoterol fumarateformamides;
phenols;
phenylethanolamines;
secondary alcohol;
secondary amino compound
00low000000
glafenineaminoquinoline;
carboxylic ester;
glycol;
organochlorine compound;
secondary amino compound
inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
guazatinealiphatic nitrogen antifungal agent;
guanidines;
secondary amino compound
antifungal agrochemical00low000000
guvacinealpha,beta-unsaturated monocarboxylic acid;
beta-amino acid;
pyridine alkaloid;
secondary amino compound;
tetrahydropyridine
GABA reuptake inhibitor;
plant metabolite
00low000000
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamidebromobenzenes;
isoquinolines;
olefinic compound;
secondary amino compound;
sulfonamide
EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor00low000000
hydroxychloroquineaminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound
anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug
00low000000
isoproterenolcatechols;
secondary alcohol;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
00low000000
ketaminecyclohexanones;
monochlorobenzenes;
secondary amino compound
analgesic;
environmental contaminant;
intravenous anaesthetic;
neurotoxin;
NMDA receptor antagonist;
xenobiotic
00low000000
labetalolbenzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound
00low000000
meclofenamic acidaminobenzoic acid;
organochlorine compound;
secondary amino compound
analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
00low000000
mefenamic acidaminobenzoic acid;
secondary amino compound
analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
00low000000
metaproterenolaralkylamino compound;
phenylethanolamines;
resorcinols;
secondary alcohol;
secondary amino compound
00low000000
n(1), n(12)-diethylsperminepolyazaalkane;
secondary amino compound;
substituted spermine;
tetramine
antineoplastic agent00low000000
fenamic acidaminobenzoic acid;
secondary amino compound
membrane transport modulator00low000000
nemonapridebenzamides;
monochlorobenzenes;
monomethoxybenzene;
N-alkylpyrrolidine;
secondary amino compound;
secondary carboxamide;
substituted aniline
00low000000
oxamniquinearomatic primary alcohol;
C-nitro compound;
quinolines;
secondary amino compound
00low000000
pd 158780aromatic amine;
bromobenzenes;
diamine;
pyridopyrimidine;
secondary amino compound
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
practololacetamides;
ethanolamines;
propanolamine;
secondary alcohol;
secondary amino compound
anti-arrhythmia drug;
beta-adrenergic antagonist
00low000000
propafenonearomatic ketone;
secondary alcohol;
secondary amino compound
anti-arrhythmia drug00low000000
salmeterol xinafoateether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound
00low000000
sotalolethanolamines;
secondary alcohol;
secondary amino compound;
sulfonamide
anti-arrhythmia drug;
beta-adrenergic antagonist;
environmental contaminant;
xenobiotic
00low000000
xylazine1,3-thiazine;
methylbenzene;
secondary amino compound
alpha-adrenergic agonist;
analgesic;
emetic;
muscle relaxant;
sedative
00low000000
phenylephrinephenols;
phenylethanolamines;
secondary amino compound
alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
00low000000
n,n'-diphenyl-4-phenylenediamineN-substituted diamine;
secondary amino compound
antioxidant00low000000
methyl n-methylanthranilatebenzoate ester;
methyl ester;
secondary amino compound;
substituted aniline
animal metabolite;
fungal metabolite;
plant metabolite
00low000000
pseudoephedrinephenylethanolamines;
secondary alcohol;
secondary amino compound
anti-asthmatic drug;
bronchodilator agent;
central nervous system drug;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
00low000000
dyrenemonochlorobenzenes;
organochlorine pesticide;
secondary amino compound;
triazines
antifungal agrochemical00low000000
propylhexedrinesecondary amino compound00low000000
4-aminodiphenylaminearomatic amine;
secondary amino compound
allergen00low000000
cyclopentaminesecondary amino compound00low000000
benzonatatebenzoate ester;
secondary amino compound;
substituted aniline
anaesthetic;
antitussive
00low000000
diisopropanolamineaminodiol;
secondary alcohol;
secondary amino compound
buffer;
emulsifier;
surfactant
00low000000
megluminehexosamine;
secondary amino compound
00low000000
cytisinealkaloid;
bridged compound;
lactam;
organic heterotricyclic compound;
secondary amino compound
nicotinic acetylcholine receptor agonist;
phytotoxin;
plant metabolite
00low000000
octamylaminesecondary amino compound00low000000
noramidopyrinepyrazoles;
secondary amino compound
antipyretic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
opioid analgesic;
peripheral nervous system drug
00low000000
diphenylaminearomatic amine;
bridged diphenyl fungicide;
secondary amino compound
antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger
00low000000
spectinomycincyclic acetal;
cyclic hemiketal;
cyclic ketone;
pyranobenzodioxin;
secondary alcohol;
secondary amino compound
antibacterial drug;
antimicrobial agent;
bacterial metabolite
00low000000
isometheptenesecondary amino compound00low000000
n-methylaspartateamino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound
neurotransmitter agent00low000000
colterolcatechols;
ethanolamines;
secondary alcohol;
secondary amino compound;
triol
anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent
00low000000
du-21220benzyl alcohols;
polyphenol;
secondary alcohol;
secondary amino compound
00low000000
amoscanateC-nitro compound;
isothiocyanate;
secondary amino compound
schistosomicide drug00low000000
norflurazone(trifluoromethyl)benzenes;
organochlorine compound;
pyridazinone;
secondary amino compound
agrochemical;
carotenoid biosynthesis inhibitor;
herbicide
00low000000
amineptinamino acid;
carbocyclic fatty acid;
carbotricyclic compound;
secondary amino compound
antidepressant;
dopamine uptake inhibitor
00low000000
bitolterolcarboxylic ester;
diester;
ethanolamines;
secondary alcohol;
secondary amino compound
anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
prodrug
00low000000
pendimethalinC-nitro compound;
secondary amino compound;
substituted aniline
agrochemical;
environmental contaminant;
herbicide
00low000000
bupirimateaminopyrimidine;
pyrimidine fungicide;
secondary amino compound;
sulfamate ester
androgen antagonist;
antifungal agrochemical
00low000000
torsemideaminopyridine;
N-sulfonylurea;
secondary amino compound
antihypertensive agent;
loop diuretic
00low000000
ractopaminebenzyl alcohols;
polyphenol;
secondary alcohol;
secondary amino compound
00low000000
temafloxacinamino acid;
monocarboxylic acid;
N-arylpiperazine;
organofluorine compound;
quinolone antibiotic;
quinolone;
secondary amino compound;
tertiary amino compound
00low000000
plerixaforazacycloalkane;
azamacrocycle;
benzenes;
crown amine;
secondary amino compound;
tertiary amino compound
anti-HIV agent;
antineoplastic agent;
C-X-C chemokine receptor type 4 antagonist;
immunological adjuvant
00low000000
sertralinedichlorobenzene;
secondary amino compound;
tetralins
antidepressant;
serotonin uptake inhibitor
00low000000
nebivololchromanes;
diol;
organofluorine compound;
secondary alcohol;
secondary amino compound
00low000000
aceclofenacamino acid;
carboxylic ester;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
tubulosinebeta-carbolines;
isoquinoline alkaloid;
isoquinolines;
phenols;
secondary amino compound;
tertiary amino compound
00low000000
2-(methylamino)isobutyric acidalanine derivative;
alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
secondary amino compound
human urinary metabolite00low000000
caldopentaminepolyazaalkane;
primary amino compound;
secondary amino compound
marine metabolite00low000000
mepanipyrimacetylenic compound;
aminopyrimidine;
anilinopyrimidine fungicide;
secondary amino compound
antifungal agrochemical;
aryl hydrocarbon receptor agonist;
hepatotoxic agent
00low000000
cyprodinilaminopyrimidine;
anilinopyrimidine fungicide;
cyclopropanes;
secondary amino compound
antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
00low000000
pyrimethanilaminopyrimidine;
anilinopyrimidine fungicide;
secondary amino compound
antifungal agrochemical;
aryl hydrocarbon receptor agonist;
environmental contaminant;
xenobiotic
00low000000
fluazinam(trifluoromethyl)benzenes;
aminopyridine;
C-nitro compound;
chloropyridine;
monochlorobenzenes;
secondary amino compound
allergen;
antifungal agrochemical;
apoptosis inducer;
environmental contaminant;
xenobiotic
00low000000
2-(3,4-dimethoxyphenyl)-5-amino-2-isopropylvaleronitriledimethoxybenzene;
nitrile;
secondary amino compound
drug metabolite;
marine xenobiotic metabolite
00low000000
phenylisopropyladenosinearomatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound
adenosine A1 receptor agonist;
neuroprotective agent
00low000000
3,4-methylenedioxyethamphetaminebenzodioxoles;
secondary amino compound
00low000000
beta-n-methylamino-l-alaninediamino acid;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid;
secondary amino compound
bacterial metabolite;
neurotoxin
00low000000
nopalineamino acid opine;
D-glutamic acid derivative;
guanidines;
L-arginine derivative;
secondary amino compound;
tricarboxylic acid
00low000000
octopineamino acid opine;
amino dicarboxylic acid;
D-alpha-amino acid zwitterion;
D-arginine derivative;
guanidines;
secondary amino compound
animal metabolite;
xenobiotic metabolite
00low000000
4'-hydroxydiclofenacdichlorobenzene;
monocarboxylic acid;
phenols;
secondary amino compound
allergen;
drug metabolite
00low000000
mannopineamino acid opine;
dicarboxylic acid monoamide;
hexitol derivative;
L-glutamine derivative;
non-proteinogenic L-alpha-amino acid;
secondary amino compound
plant metabolite00low000000
ezogabinecarbamate ester;
organofluorine compound;
secondary amino compound;
substituted aniline
anticonvulsant;
potassium channel modulator
00low000000
aj 76secondary amino compound;
tetralins
dopaminergic antagonist00low000000
nsc 2240701,4-benzoquinones;
aziridines;
enamine;
primary alcohol;
secondary amino compound
alkylating agent;
antineoplastic agent
00low000000
als 8123carboxylic acid;
ethanolamines;
secondary amino compound
00low000000
7-nitrobenzoxadiazole-6-aminohexanoic acidbenzoxadiazole;
C-nitro compound;
epsilon-amino acid;
secondary amino compound
fluorochrome00low000000
5,5,7,12,12,14-hexamethyl-1,4,8,11-tetrazacyclotetradecanesecondary amino compound00low000000
cox 189amino acid;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
secondary amino compound
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
00low000000
vatalanibmonochlorobenzenes;
phthalazines;
pyridines;
secondary amino compound
angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist
00low000000
cinacalcet(trifluoromethyl)benzenes;
naphthalenes;
secondary amino compound
calcimimetic;
P450 inhibitor
00low000000
guvacolinealpha,beta-unsaturated carboxylic ester;
beta-amino acid ester;
enoate ester;
methyl ester;
pyridine alkaloid;
secondary amino compound;
tetrahydropyridine
muscarinic agonist;
plant metabolite
00low000000
baeocystinorganic phosphate;
secondary amino compound;
tryptamine alkaloid
fungal metabolite;
hallucinogen
00low000000
dizocilpinesecondary amino compound;
tetracyclic antidepressant
anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
00low000000
melagatranazetidines;
carboxamidine;
dicarboxylic acid monoamide;
non-proteinogenic alpha-amino acid;
secondary amino compound
anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
serine protease inhibitor
00low000000
alpha-putrescinylthymineN-substituted putrescine;
pyrimidine nucleobase;
pyrimidone;
secondary amino compound;
tertiary amino compound
00low000000
demecolcinealkaloid;
secondary amino compound
antineoplastic agent;
microtubule-destabilising agent
00low000000
nsc 23766aminopyrimidine;
aminoquinoline;
primary amino compound;
secondary amino compound;
tertiary amino compound
antiviral agent;
apoptosis inducer;
EC 3.6.5.2 (small monomeric GTPase) inhibitor;
muscarinic antagonist
00low000000
norbelladinecatechols;
phenethylamine alkaloid;
polyphenol;
secondary amino compound
plant metabolite00low000000
e 3040benzothiazoles;
organic hydroxy compound;
pyridines;
secondary amino compound
anti-inflammatory drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
uricosuric drug
00low000000
E3040 glucuronidebenzothiazoles;
beta-D-glucosiduronic acid;
pyridines;
secondary amino compound
xenobiotic metabolite00low000000
validamycin aantibiotic fungicide;
polyol;
secondary amino compound;
validamycins
antifungal agrochemical;
EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor;
EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor;
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor
00low000000
ergonovineergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound
diagnostic agent;
fungal metabolite;
oxytocic;
toxin
00low000000
1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-onebenzoic acids;
primary alcohol;
pyrrolidin-2-ones;
secondary amino compound
00low000000
tolfenamic acidaminobenzoic acid;
organochlorine compound;
secondary amino compound
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
N-benzylquinazolin-4-aminebenzenes;
quinazolines;
secondary amino compound
00low000000
s 1033(trifluoromethyl)benzenes;
imidazoles;
pyridines;
pyrimidines;
secondary amino compound;
secondary carboxamide
anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-aminearomatic amine;
monofluorobenzenes;
pyridines;
quinazolines;
secondary amino compound;
substituted aniline
00low000000
lolineloline alkaloid;
secondary amino compound
00low000000
SMER 28organobromine compound;
quinazolines;
secondary amino compound
autophagy inducer00low000000
amn082benzenes;
diamine;
diarylmethane;
secondary amino compound
metabotropic glutamate receptor agonist;
neuroprotective agent
00low000000
N-{3-[(2-phenylquinazolin-4-yl)amino]phenyl}acetamideacetamide;
aromatic amine;
quinazolines;
secondary amino compound;
substituted aniline
00low000000
spiraprilatazaspiro compound;
dicarboxylic acid;
dipeptide;
dithioketal;
pyrrolidinecarboxylic acid;
secondary amino compound;
tertiary carboxamide
antihypertensive agent;
drug metabolite;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
00low000000
5-hydroxydiclofenacdichlorobenzene;
monocarboxylic acid;
phenols;
secondary amino compound
allergen;
drug metabolite
00low000000
dasatinib1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound
anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
00low000000
noribogainemonoterpenoid indole alkaloid;
organic heteropentacyclic compound;
secondary amino compound;
tertiary amino compound
kappa-opioid receptor agonist;
NMDA receptor antagonist;
psychotropic drug;
serotonin uptake inhibitor
00low000000
6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolineorganic heterotricyclic compound;
organofluorine compound;
pyridines;
secondary amino compound
00low000000
n,o-didesmethylvenlafaxinecyclohexanols;
phenols;
secondary amino compound
drug metabolite;
marine xenobiotic metabolite
00low000000
n-desmethylvenlafaxinecyclohexanols;
monomethoxybenzene;
secondary amino compound
drug metabolite;
marine xenobiotic metabolite
00low000000
sb 415286C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline
antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
00low000000
N-(3-{[2-(2-fluorophenyl)quinazolin-4-yl]amino}phenyl)acetamideacetamide;
aromatic amine;
monofluorobenzenes;
quinazolines;
secondary amino compound;
substituted aniline
00low000000
N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-aminearomatic amine;
piperidines;
pyridines;
quinazolines;
secondary amino compound;
tertiary amino compound
00low000000
chanoclavinebenzoindole;
ergot alkaloid;
organic heterotricyclic compound;
primary alcohol;
secondary amino compound
00low000000
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin1,4-benzoquinones;
ansamycin;
carbamate ester;
secondary amino compound;
tertiary amino compound
Hsp90 inhibitor00low000000
spiraprilazaspiro compound;
dicarboxylic acid monoester;
dipeptide;
dithioketal;
ethyl ester;
pyrrolidinecarboxylic acid;
secondary amino compound;
tertiary carboxamide
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
00low000000
palbociclibaminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
00low000000
trandolaprilatdicarboxylic acid;
dipeptide;
organic heterobicyclic compound;
secondary amino compound;
tertiary carboxamide
antihypertensive agent;
drug metabolite;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
human xenobiotic metabolite
00low000000
amocarzineC-nitro compound;
N-methylpiperazine;
secondary amino compound;
thioureas
antinematodal drug00low000000
imidaprildicarboxylic acid monoester;
dipeptide;
ethyl ester;
imidazolidines;
N-acylurea;
secondary amino compound
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
00low000000
imidaprilatdicarboxylic acid;
dipeptide;
imidazolidines;
N-acylurea;
secondary amino compound
antihypertensive agent;
drug metabolite;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
00low000000
ximelagatranamidoxime;
azetidines;
carboxamide;
ethyl ester;
hydroxylamines;
secondary amino compound;
secondary carboxamide;
tertiary carboxamide
anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
prodrug;
serine protease inhibitor
00low000000
trandolaprildicarboxylic acid monoester;
dipeptide;
ethyl ester;
organic heterobicyclic compound;
secondary amino compound;
tertiary carboxamide
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
00low000000
GSK3-XIIIaromatic amine;
pyrazoles;
quinazolines;
secondary amino compound
EC 2.7.11.26 (tau-protein kinase) inhibitor00low000000
robenacoxibaromatic amino acid;
monocarboxylic acid;
organofluorine compound;
phenylacetic acids;
secondary amino compound
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
00low000000
tanespimycin1,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
Hsp90 inhibitor
00low000000
indacaterolindanes;
monohydroxyquinoline;
quinolone;
secondary alcohol;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent
00low000000
panobinostatcinnamamides;
hydroxamic acid;
methylindole;
secondary amino compound
angiogenesis modulating agent;
antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor
00low000000
bis(7)-tacrinesecondary amino compoundapoptosis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neuroprotective agent
00low000000
r 115866aromatic amine;
benzothiazoles;
secondary amino compound;
triazoles
00low000000
pd 0325901difluorobenzene;
hydroxamic acid ester;
monofluorobenzenes;
organoiodine compound;
propane-1,2-diols;
secondary amino compound
antineoplastic agent;
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
00low000000
dysiherbaineamino dicarboxylic acid;
furopyran;
hydroxy carboxylic acid;
secondary amino compound
animal metabolite;
excitatory amino acid agonist;
marine metabolite;
neurotoxin
00low000000
cangreloradenosine 5'-phosphate;
aryl sulfide;
nucleoside triphosphate analogue;
organochlorine compound;
organofluorine compound;
secondary amino compound
P2Y12 receptor antagonist;
platelet aggregation inhibitor
00low000000
mocetinostataminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
00low000000
ticagreloraryl sulfide;
hydroxyether;
organofluorine compound;
secondary amino compound;
triazolopyrimidines
P2Y12 receptor antagonist;
platelet aggregation inhibitor
00low000000
solabegroncarboxybiphenyl;
monochlorobenzenes;
secondary alcohol;
secondary amino compound;
substituted aniline
beta-adrenergic agonist00low000000
rucaparibazepinoindole;
caprolactams;
organofluorine compound;
secondary amino compound
antineoplastic agent;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
00low000000
chir 99021aminopyridine;
aminopyrimidine;
cyanopyridine;
diamine;
dichlorobenzene;
imidazoles;
secondary amino compound
EC 2.7.11.26 (tau-protein kinase) inhibitor00low000000
azd 6244benzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monochlorobenzenes;
organofluorine compound;
secondary amino compound
anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
vilanterolbenzyl alcohols;
dichlorobenzene;
ether;
phenols;
secondary amino compound
beta-adrenergic agonist;
bronchodilator agent
00low000000
binimetinibbenzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monofluorobenzenes;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
3-epi-fagomineamino monosaccharide;
hydroxypiperidine;
primary alcohol;
secondary alcohol;
secondary amino compound;
triol
EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor;
EC 3.2.1.23 (beta-galactosidase) inhibitor;
plant metabolite
00low000000
ethaboxam1,3-thiazoles;
aromatic amide;
aromatic amine;
nitrile;
secondary amino compound;
thiophenes
00low000000
abt-737aromatic amine;
aryl sulfide;
biphenyls;
C-nitro compound;
monochlorobenzenes;
N-arylpiperazine;
N-sulfonylcarboxamide;
secondary amino compound;
tertiary amino compound
anti-allergic agent;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
00low000000
validoxylamine aamino cyclitol;
secondary amino compound
animal metabolite;
antibiotic insecticide;
bacterial metabolite;
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor
00low000000
azd 1152anilide;
monoalkyl phosphate;
monofluorobenzenes;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound
antineoplastic agent;
Aurora kinase inhibitor;
prodrug
00low000000
pf 00299804enamide;
monochlorobenzenes;
monofluorobenzenes;
piperidines;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound
antineoplastic agent;
epidermal growth factor receptor antagonist
00low000000
finafloxacincyclopropanes;
monocarboxylic acid;
nitrile;
organofluorine compound;
quinolone;
secondary amino compound;
tertiary amino compound
antibacterial drug;
antimicrobial agent
00low000000
sarpagineindole alkaloid;
phenols;
primary alcohol;
secondary amino compound;
tertiary amino compound
00low000000
vizamyl(18)F radiopharmaceutical;
aromatic amine;
benzothiazoles;
secondary amino compound
radioactive imaging agent00low000000
azd 1152-hqpaanilide;
monofluorobenzenes;
primary alcohol;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound
antineoplastic agent;
Aurora kinase inhibitor
00low000000
gdc-0973aromatic amine;
difluorobenzene;
N-acylazetidine;
organoiodine compound;
piperidines;
secondary amino compound;
tertiary alcohol
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
00low000000
pevonedistatcyclopentanols;
indanes;
pyrrolopyrimidine;
secondary amino compound;
sulfamidate
antineoplastic agent;
apoptosis inducer
00low000000
tg101209N-alkylpiperazine;
N-arylpiperazine;
pyrimidines;
secondary amino compound;
sulfonamide
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
00low000000
WAY-316606(trifluoromethyl)benzenes;
piperidines;
secondary amino compound;
sulfonamide;
sulfone
secreted frizzled-related protein 1 inhibitor00low000000
asp3026aromatic amine;
diamino-1,3,5-triazine;
monomethoxybenzene;
N-methylpiperazine;
piperidines;
secondary amino compound;
sulfone
antimalarial;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
00low000000
entrectinibbenzamides;
difluorobenzene;
indazoles;
N-methylpiperazine;
oxanes;
secondary amino compound;
secondary carboxamide
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
pexidartinibaminopyridine;
organochlorine compound;
organofluorine compound;
pyrrolopyridine;
secondary amino compound
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
(R)-DRF0532,6-diaminopurines;
phenylpyridine;
primary alcohol;
secondary amino compound
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor00low000000
GDC-0623hydroxamic acid ester;
imidazopyridine;
monofluorobenzenes;
organoiodine compound;
primary alcohol;
secondary amino compound;
substituted aniline
antineoplastic agent;
apoptosis inducer;
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
00low000000
cblc137aromatic ketone;
carbazoles;
methyl ketone;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
NF-kappaB inhibitor;
p53 activator
00low000000
mephedroneamphetamines;
aromatic ketone;
secondary amino compound
environmental contaminant;
xenobiotic
00low000000
ml228 probe1,2,4-triazines;
biphenyls;
pyridines;
secondary amino compound
hypoxia-inducible factor pathway activator00low000000
gilteritinibaromatic amine;
monomethoxybenzene;
N-methylpiperazine;
oxanes;
piperidines;
primary carboxamide;
pyrazines;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
chir 98014aminopyrimidine;
C-nitro compound;
diaminopyridine;
dichlorobenzene;
imidazoles;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
hypoglycemic agent;
tau aggregation inhibitor;
Wnt signalling activator
00low000000
AZD3463aminopiperidine;
aminopyrimidine;
indoles;
monomethoxybenzene;
organochlorine compound;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
00low000000
gsk2879552benzenes;
benzoic acids;
cyclopropanes;
monocarboxylic acid;
piperidines;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
00low000000
ML355benzothiazoles;
monomethoxybenzene;
phenols;
secondary amino compound;
substituted aniline;
sulfonamide
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
platelet aggregation inhibitor
00low000000
osimertinibacrylamides;
aminopyrimidine;
biaryl;
indoles;
monomethoxybenzene;
secondary amino compound;
secondary carboxamide;
substituted aniline;
tertiary amino compound
antineoplastic agent;
epidermal growth factor receptor antagonist
00low000000
ly3009120aminotoluene;
aromatic amine;
biaryl;
monofluorobenzenes;
phenylureas;
pyridopyrimidine;
secondary amino compound
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
B-Raf inhibitor;
necroptosis inhibitor
00low000000
as 1842856organofluorine compound;
primary amino compound;
quinolinemonocarboxylic acid;
quinolone;
secondary amino compound;
tertiary amino compound
anti-obesity agent;
antineoplastic agent;
apoptosis inducer;
autophagy inhibitor;
forkhead box protein O1 inhibitor;
hypoglycemic agent
00low000000
hg-9-91-01aminopyrimidine;
dimethoxybenzene;
N-alkylpiperazine;
N-arylpiperazine;
phenylureas;
secondary amino compound
antineoplastic agent;
salt-inducible kinase 2 inhibitor
00low000000
praliciguataminopyrimidine;
isoxazoles;
monofluorobenzenes;
organofluorine compound;
pyrazoles;
secondary amino compound;
tertiary alcohol
anti-inflammatory agent;
antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent
00low000000
chrysopineamino acid opine;
carboxamide;
delta-lactone;
secondary amino compound;
spiroketal;
triol
plant metabolite00low000000
enasidenib1,3,5-triazines;
aminopyridine;
aromatic amine;
organofluorine compound;
secondary amino compound;
tertiary alcohol
antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
00low000000
BDA-366anthraquinone;
epoxide;
secondary alcohol;
secondary amino compound;
tertiary amino compound
antineoplastic agent;
apoptosis inducer
00low000000
THZ531aminopyrimidine;
enamide;
indoles;
N-acylpiperidine;
organochlorine compound;
secondary amino compound;
secondary carboxamide
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
00low000000
indolmycin1,3-oxazoles;
indoles;
secondary amino compound
antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor
00low000000
ethirimolaminopyrimidine;
pyrimidine fungicide;
pyrimidone;
secondary amino compound
antifungal agrochemical00low000000
liproxstatin-1azaspiro compound;
monochlorobenzenes;
organic heterotricyclic compound;
secondary amino compound
antioxidant;
cardioprotective agent;
ferroptosis inhibitor;
radical scavenger
00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
u 0126aryl sulfide;
dinitrile;
enamine;
substituted aniline
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
00low000000
quercetin 3-o-glucopyranosidebeta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone
antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite
00low000000
salvianolic acid B1-benzofurans;
catechols;
dicarboxylic acid;
enoate ester;
polyphenol
anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
autophagy inhibitor;
cardioprotective agent;
hepatoprotective agent;
hypoglycemic agent;
neuroprotective agent;
osteogenesis regulator;
plant metabolite
00low000000
jte 013chloropyridine;
pyrazolopyridine
anti-asthmatic agent;
anti-inflammatory agent;
antineoplastic agent;
osteogenesis regulator;
pro-angiogenic agent;
sphingosine-1-phosphate receptor 2 antagonist
00low000000
halcinonideorganic molecular entitySMO receptor agonist00low000000
clobetasol11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid;
tertiary alpha-hydroxy ketone
anti-inflammatory drug;
SMO receptor agonist
00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
itraconazolepiperazines2010201014.0low000100
veratraminepiperidine alkaloid2010201014.0low000100
jervinepiperidines2010201014.0low000100
25-hydroxycholesterol25-hydroxy steroid;
oxysterol
human metabolite2010201014.0low000100
(20s)-20-hydroxycholesterol20-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol
human metabolite;
mouse metabolite
2010201014.0low000100
24-hydroxycholesterol24-hydroxycholesterolbiomarker;
human blood serum metabolite;
mouse metabolite
2010201014.0medium000100
22s-hydroxycholesterol22-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol
2010201014.0medium000100
gant58pyridines2010201014.0low000100
gant 61aminal;
dialkylarylamine;
pyridines;
substituted aniline;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
glioma-associated oncogene inhibitor;
Hedgehog signaling pathway inhibitor
2010201014.0low000100
cyclopaminepiperidinesglioma-associated oncogene inhibitor2006201016.0low000200
sag compound2006201613.3high000210
fexaraminebiphenyls2005200519.0low000100
tubacin1,3-oxazoles2005200519.0low000100
tws 119pyrroles2005200519.0low000100
cardiogenol cmethoxybenzenes;
substituted aniline
2005200519.0low000100
gdc 0449benzamides;
monochlorobenzenes;
pyridines;
sulfone
antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist;
teratogenic agent
2010201014.0low000100
robotnikinin2010201014.0medium000100
physalin fenone;
epoxy steroid;
lactone;
physalin
antileishmanial agent;
antimalarial;
antineoplastic agent;
apoptosis inducer;
immunosuppressive agent
2010201014.0low000100
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
lactic acid2-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
2014201410.0low000010
valproic acidbranched-chain fatty acid;
branched-chain saturated fatty acid
anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
2011201113.0low000010
metforminguanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
201720177.0low000010
bromodeoxyuridinepyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
202120213.0low000001
thiophenesmancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound
non-polar solvent200920209.2low000140
quinazolinesazaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
2013201311.0low000010
durapatite201720177.0low000010
amiloridearomatic amine;
guanidines;
organochlorine compound;
pyrazines
diuretic;
sodium channel blocker
201720177.0low000010
fluorescein-5-isothiocyanatefluorescein isothiocyanate201820186.0low000010
n-methylaspartateamino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound
neurotransmitter agent201620168.0low000010
titaniumtitanium group element atom2005202011.3low000120
tricalcium phosphatecalcium phosphate2011201610.7low000030
colforsinacetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol
adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
2004201913.0low000210
25-hydroxycholesterol25-hydroxy steroid;
oxysterol
human metabolite2014201410.0low000010
tomatidine3beta-hydroxy steroid;
azaspiro compound;
oxaspiro compound
2009200915.0low000100
cyc 2022,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
201720177.0low000010
gant 61aminal;
dialkylarylamine;
pyridines;
substituted aniline;
tertiary amino compound
antineoplastic agent;
apoptosis inducer;
glioma-associated oncogene inhibitor;
Hedgehog signaling pathway inhibitor
202120213.0low000001
cyclopaminepiperidinesglioma-associated oncogene inhibitor2004202010.8medium000490
tretinoinretinoic acid;
vitamin A
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
2008201911.3medium000380
gw 3965diarylmethane2009200915.0low000100
t09013172009200915.0low000100
h 89N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide2010201014.0low000100
tamoxifenstilbenoid;
tertiary amino compound
angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
2014201410.0low000010
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamidebenzamides;
benzodioxoles;
imidazoles;
pyridines
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor2011201113.0low000010
genistein7-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
201720177.0low000010
sag compound202020204.0low000010
sirolimusantibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol
antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
2013201311.0low000010
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl estercarboxylic ester;
difluorobenzene;
dipeptide;
tert-butyl ester
EC 3.4.23.46 (memapsin 2) inhibitor2014201410.0low000010
pregna-4,17-diene-3,16-dione3-hydroxy steroidandrogen201920195.0low000010
trisialoganglioside gt12012201610.0low000020
chir 99021aminopyridine;
aminopyrimidine;
cyanopyridine;
diamine;
dichlorobenzene;
imidazoles;
secondary amino compound
EC 2.7.11.26 (tau-protein kinase) inhibitor2011201411.5low000020
bucladesine3',5'-cyclic purine nucleotide2011201113.0low000010
gdc 0449benzamides;
monochlorobenzenes;
pyridines;
sulfone
antineoplastic agent;
Hedgehog signaling pathway inhibitor;
SMO receptor antagonist;
teratogenic agent
2009200915.0low000100
4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBODIPY compound202020204.0low000010
bms-8339232013201311.0low000010
cyclin d1201220179.5low000020
tomatine2009200915.0low000100
phenylamilguanidines;
pyrazines
201720177.0low000010
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Abnormalities, Multiple0201720177.0low000010
Adenoma, Prostatic02014201410.0low000010
Age-Related Osteoporosis0201920195.0low000010
Akinetic-Rigid Variant of Huntington Disease02011201113.0low000010
Anemia, Cooley's0201820186.0low000010
Apoplexy02014201410.0low000010
Arachnoidal Cerebellar Sarcoma, Circumscribed02010201014.0low000100
Benign Cerebellar Neoplasms02010201014.0low000100
Benign Neoplasms02010201014.0low000100
beta-Thalassemia0201820186.0low000010
Brain Inflammation0201820186.0low000010
Brain Ischemia02014201410.0low000010
Cancer of Liver0201720177.0low000010
Cancer of Lung0201720177.0low000010
Cancer of Prostate02013201311.0low000010
Cancer of Skin02012201212.0low000010
Carcinoma, Basal Cell02012201212.0low000010
Carcinoma, Basal Cell, Pigmented02012201212.0low000010
Carcinoma, Hepatocellular0201720177.0low000010
Cardiovascular Stroke0201820186.0low000010
Cell Transformation, Neoplastic02012201710.0low000030
Cerebral Ischemia02014201410.0low000010
Chronic Kidney Failure0201720177.0low000010
Ciliopathies0201720177.0low000010
Colorectal Cancer0202120213.0low000001
Colorectal Neoplasms0202120213.0low000001
Congenital Zika Syndrome0202020204.0low000010
Cystic Kidney Diseases0201720177.0low000010
Disease Models, Animal0201420206.2low000040
Encephalitis0201820186.0low000010
Eye Abnormalities0201720177.0low000010
Hepatocellular Carcinoma0201720177.0low000010
Huntington Disease02011201113.0low000010
Hyperdactyly02008200816.0low000100
Idiopathic Parkinson Disease0201720177.0low000010
Inflammation0201420178.5low000020
Injuries, Spinal Cord02014201410.0low000010
Injury, Myocardial Reperfusion0201820186.0low000020
Innate Inflammatory Response0201420178.5low000020
Kidney Diseases, Cystic0201720177.0low000010
Kidney Failure, Chronic0201720177.0low000010
Kidney, Polycystic0201720177.0low000010
Liver Neoplasms0201720177.0low000010
Lung Neoplasms0201720177.0low000010
Medulloblastoma02010201014.0low000100
Myocardial Infarction0201820186.0low000010
Neoplasms02010201014.0low000100
Osteolysis0202020204.0low000010
Osteoporosis0201920195.0low000010
Parkinson Disease0201720177.0low000010
Polycystic Kidney Diseases0201720177.0low000010
Prostatic Hyperplasia02014201410.0low000010
Prostatic Neoplasms02013201311.0low000010
Sensitivity and Specificity0201620168.0low000010
Skin Neoplasms02012201212.0low000010
Spinal Cord Injuries02014201410.0low000010
Stroke02014201410.0low000010
Zika Virus Infection0202020204.0low000010

Bioavailability (2)

ArticleYear
Discovery of small-molecule modulators of the secretin receptor: Purmorphamine as novel anti-hypertensive agent.
European journal of medicinal chemistry, , Nov-15, Volume: 242
2022
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, , Volume: 96, Issue:5
2019