Page last updated: 2024-08-01 21:51:58

c.i. fluorescent brightening agent 28

Description

Cross-References

ID SourceID
PubMed CID6108780
CHEMBL ID1256580
SCHEMBL ID790332
CHEBI ID50010
MeSH IDM0049998

Synonyms (45)

Synonym
AC-12935
fluorescent brightener 28, used as a stain and brightening agent
2,2'-stilbenedisulfonic acid, 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-
benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis(5-((4-(bis(2-hydroxyethyl)amino)-6-(phenylamino)-1,3,5-triazin-2-yl)amino)-
einecs 224-548-7
calcofluor m2r
4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbene disulfonic acid
tinopal lpw
4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulfonic acid
fluorescent brightener 28
tinopal unpa-gx
calcofluor white m2r
4,4'-bis((4-(bis(2-hydroxyethyl)amino)-6-anilino-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonic acid
benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis[5-[[4-[bis(2-hydroxyethyl)amino]-6-(phenylamino)-1,3,5-triazin-2-yl]amino]-
4404-43-7
2,2'-(e)-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonic acid]
c.i. fluorescent brightening agent 28
calcofluor
4193-55-9
4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid
4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid
calcofluor white
2,2'-ethene-1,2-diylbis[5-({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonic acid]
CHEBI:50010
5-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-[(e)-2-[4-[[4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid
fluorescent brightener
CHEMBL1256580
4,4'-bis(4-(bis(2-hydroxyethyl)amino)-6-anilino-1,3,5-triazin-2-yl)amino)stilbene-2,2'-disulphonic acid
ec 224-548-7
7s9p0y4313 ,
unii-7s9p0y4313
AKOS015894290
SCHEMBL790332
4,4'-bis(2-anilino-4-(bis(hydroxyethyl)amino)-s-triazin-6-ylamino)-2,2'-stilbenedisulfonic acid
fluorescent brightener 28 free acid
phorwite bbh
c.i. fluorescent brightening agent 28, (e)-
c.i. fluorescent brightener 28, free acid
4,4'-bis((4-anilino-6-bis((2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbenedisulfonic acid
ci fluorescent brightening agent 28
6,6'-(ethene-1,2-diyl)bis(3-((4-(bis(2-hydroxyethyl)amino)-6-(phenylamino)-1,3,5-triazin-2-yl)amino)benzenesulfonic acid)
CNGYZEMWVAWWOB-VAWYXSNFSA-N
Q27121661
Q27268792
STARBLD0009593

Bioassays (2)

Assay IDTitleYearJournalArticle
AID522114Antimicrobial activity against Candida glabrata TG162 containing calcineurin deltacnb1 mutant at 0.8 mg/ml after 48 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
ISSN: 1098-6596
Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.
AID522113Antimicrobial activity against Candida glabrata TG172 containing deltacrz1 mutant at 0.8 mg/ml after 48 hrs2010Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4
ISSN: 1098-6596
Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.

Research

Studies (321)

TimeframeStudies, This Drug (%)All Drugs %
pre-199026 (8.10)18.7374
1990's62 (19.31)18.2507
2000's114 (35.51)29.6817
2010's94 (29.28)24.3611
2020's25 (7.79)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (0.88%)5.53%
Reviews6 (1.76%)6.00%
Case Studies6 (1.76%)4.05%
Observational0 (0.00%)0.25%
Other326 (95.60%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
fluconazoleconazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug
environmental contaminant;
P450 inhibitor;
xenobiotic
2010201014.0low000100
itraconazolepiperazines2010201014.0low000100
miconazoledichlorobenzene;
ether;
imidazoles
2010201014.0low000100
congo redbis(azo) compound2010201014.0low000100
voriconazoleconazole antifungal drug;
difluorobenzene;
pyrimidines;
tertiary alcohol;
triazole antifungal drug
P450 inhibitor2010201014.0low000100
micafunginantibiotic antifungal drug;
echinocandin
antiinfective agent2010201014.0low000100
amphotericin bantibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic
antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
2010201014.0low000100
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
quinacrineacridines;
aromatic ether;
organochlorine compound;
tertiary amino compound
antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
2003200321.0low000100
phloroglucinolbenzenetriol;
phenolic donor
algal metabolite2012201212.0low000010
ethanolamineethanolamines;
primary alcohol;
primary amine
Escherichia coli metabolite;
human metabolite;
mouse metabolite
201520159.0low000010
glycerolalditol;
triol
algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
2000200024.0low001000
hydrogenelemental hydrogen;
elemental molecule;
gas molecular entity
antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
202020204.0low000010
1-anilino-8-naphthalenesulfonateaminonaphthalene;
naphthalenesulfonic acid
fluorescent probe2011201113.0low000010
2,2'-dipyridylbipyridinechelator;
ferroptosis inhibitor
201620168.0low000010
caffeinepurine alkaloid;
trimethylxanthine
adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
1994202020.3low005820
eucalyptol201720177.0low000010
dapiindolesfluorochrome2000201516.8low001120
erythrosine1985201827.3low031110
fluconazoleconazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug
environmental contaminant;
P450 inhibitor;
xenobiotic
201620168.0low000010
vitamin k 31,4-naphthoquinones;
vitamin K
angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
2008200915.3low000300
methenaminepolyazaalkane;
polycyclic cage;
tetramine
antibacterial drug1998200721.5low001100
propidiumphenanthridines;
quaternary ammonium ion
fluorochrome;
intercalator
1987201622.0low011110
sorbitolglucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
1995201517.1low002320
glutamineamino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
202220222.0low000001
uridine diphosphatepyrimidine ribonucleoside 5'-diphosphate;
uridine 5'-phosphate
Escherichia coli metabolite;
mouse metabolite
202220222.0low000001
galactoseD-galactose;
galactopyranose
Escherichia coli metabolite;
mouse metabolite
2007201910.2low000130
methylene blueorganic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
2000200024.0low001000
cycloheximideantibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol
anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
1988198836.0low010000
egtazic aciddiether;
tertiary amino compound;
tetracarboxylic acid
chelator2005200519.0low000100
n-pentanolpentanol;
short-chain primary fatty alcohol
human metabolite;
plant metabolite
2004200420.0low000100
tryptophanerythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan
antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
2001200521.0low000300
alpha-pinenepineneplant metabolite201720177.0low000010
rhodamine borganic chloride salt;
xanthene dye
fluorescent probe;
fluorochrome;
histological dye
201920195.0low000010
pyocyanineiminium betaine;
phenazines
antibacterial agent;
bacterial metabolite;
biological pigment;
virulence factor
201920195.0low000010
tolonium chloride1998201915.3low001110
trehalosetrehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2009200915.0low000100
4-cymenemonoterpene;
toluenes
human urinary metabolite;
plant metabolite;
volatile oil component
201720177.0low000010
allyl alcoholprimary allylic alcohol;
propenol
antibacterial agent;
fungicide;
herbicide;
insecticide;
plant metabolite
2000200024.0low001000
cyclohexanolcyclohexanols;
secondary alcohol
solvent201720177.0low000010
pyrrolespyrrole;
secondary amine
202020204.0low000010
thiophenesmancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound
non-polar solvent201620168.0low000010
benzoxazoles1,3-benzoxazoles;
mancude organic heterobicyclic parent
201620168.0low000010
isoxazolesisoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
2001200123.0low000100
thiazoles1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
2014201410.0low000010
evans blueorganic sodium saltfluorochrome;
histological dye;
sodium channel blocker;
teratogenic agent
1985201025.3low010200
aminoimidazole carboxamideaminoimidazole;
monocarboxylic acid amide
mouse metabolite201920195.0low000010
hydantoinsimidazolidine-2,4-dione201920195.0low000010
hematoxylinorganic heterotetracyclic compound;
oxacycle;
polyphenol;
tertiary alcohol
histological dye;
plant metabolite
2003201914.3low000210
uranyl acetate2010201014.0low000100
eosine yellowish-(ys)organic sodium salt;
organobromine compound
fluorochrome;
histological dye
2000202015.4low001330
gentian violetorganic chloride saltanthelminthic drug;
antibacterial agent;
antifungal agent;
antiseptic drug;
histological dye
1997199727.0low001000
neutral redhydrochlorideacid-base indicator;
dye;
two-colour indicator
1985201822.5low010010
congo redbis(azo) compound1985202216.5medium03317102
acetylcysteineacetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid
antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
201620168.0low000010
potassium hydroxidealkali metal hydroxide1985202211.5low110526
paraquatorganic cationgeroprotector;
herbicide
2011201113.0low000010
fluorescein2-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye
fluorescent dye;
radioopaque medium
1985198539.0low010000
thioflavin torganic chloride saltfluorochrome;
geroprotector;
histological dye
2014201410.0low000010
c.i. direct blue 1201620168.0low000010
2,2-bis(bromomethyl)-1,3-propanediolprimary alcohol1994200026.5low004000
fluorescein-5-isothiocyanatefluorescein isothiocyanate1983201229.7low020010
mannoseD-aldohexose;
D-mannose;
mannopyranose
metabolite1994199430.0low001000
dithiothreitol1,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol
chelator;
human metabolite;
reducing agent
2010201014.0low000100
limonenecycloalkene;
p-menthadiene
human metabolite201320179.0low000020
manganeseelemental manganese;
manganese group element atom
Escherichia coli metabolite;
micronutrient
2005200519.0low000100
acetylglucosamineN-acetyl-D-glucosamineepitope2013201311.0low000010
phosphotyrosineL-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine
Escherichia coli metabolite;
immunogen
1999199925.0low001000
isopentyl alcoholalkyl alcohol;
primary alcohol;
volatile organic compound
antifungal agent;
Saccharomyces cerevisiae metabolite;
xenobiotic metabolite
2004200420.0low000100
diflubenzuronbenzoylurea insecticide;
monochlorobenzenes
insect sterilant2008201014.7low000300
iprodionebenzenes;
dichlorophenyl dicarboximide fungicide;
imidazole fungicide;
imidazolidine-2,4-dione;
ureas
antifungal agrochemical;
nematicide
201920195.0low000010
itraconazolearomatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor
2006202110.3low000111
vanadatestrivalent inorganic anion;
vanadium oxoanion
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
2003200321.0low000100
acridine orangeaminoacridines;
aromatic amine;
tertiary amino compound
fluorochrome;
histological dye
1998201419.0low001110
glucose, (beta-d)-isomerD-glucopyranoseepitope;
mouse metabolite
201220208.3low000030
diacetylfluorescein1987201822.7low011010
triazoles1,2,3-triazole2006201911.5low000110
delphinidinanthocyanidin chloride1988198836.0low010000
voriconazoleconazole antifungal drug;
difluorobenzene;
pyrimidines;
tertiary alcohol;
triazole antifungal drug
P450 inhibitor2006202210.0low000101
tebuconazolemonochlorobenzenes;
tertiary alcohol;
triazoles
201920195.0low000010
fludioxonilbenzodioxoles;
nitrile;
organofluorine compound;
pyrroles
androgen antagonist;
antifungal agrochemical;
estrogen receptor agonist
202020204.0low000010
teflubenzurondichlorobenzene;
difluorobenzene;
N-acylurea
environmental contaminant;
insecticide;
xenobiotic
2010201014.0low000100
glycidyl nitrate201720177.0low000010
fast red ta2001200123.0low000100
n-acetyldopamineacetamides;
catechols;
N-(fatty acyl)-dopamine;
secondary carboxamide
human urinary metabolite;
marine metabolite
2001200123.0low000100
diacetyldichlorofluorescein2003200321.0low000100
glycerophosphoinositol 4,5-bisphosphate201620168.0low000010
aspartamecarboxylic acid;
dipeptide zwitterion;
dipeptide;
methyl ester
apoptosis inhibitor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
environmental contaminant;
micronutrient;
nutraceutical;
sweetening agent;
xenobiotic
202020204.0low000010
dithiothreitol tetraacetate2010201014.0low000100
biotinbiotins;
vitamin B7
coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
1998200622.3low001200
lignin2010201610.3low000120
4,4'-bis(2-di(2-hydroxyethyl)amino-4-(3-sulphophenylamino)-1,3,5-triazine-6-ylamino)stilbene-2,2'-disulphonic acid1988201816.7high010020
glucosamineD-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
1994199430.0low001000
epiglucan1995202315.5low003532
laminaran1995201519.0low001010
cellulasecellotriose2006202011.0low000110
phalloidinehomodetic cyclic peptide1991200329.0low002100
steviosidebeta-D-glucoside;
bridged compound;
diterpene glycoside;
ent-kaurane diterpenoid;
tetracyclic diterpenoid
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
hypoglycemic agent;
plant metabolite;
sweetening agent
202020204.0low000010
naringin(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside
anti-inflammatory agent;
antineoplastic agent;
metabolite
202020204.0low000010
ergosterol3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols
fungal metabolite;
Saccharomyces cerevisiae metabolite
2011201113.0low000010
tacrolimusmacrolide lactambacterial metabolite;
immunosuppressive agent
1999199925.0low001000
pectinsD-galactopyranuronic acid2012201212.0low000010
laminaran1991199133.0low001000
l 743,872200520199.8low000170
micafunginantibiotic antifungal drug;
echinocandin
antiinfective agent2010201014.0low000100
glycosides1985198539.0low010000
stilbenesstilbene1980200630.0low011100
phenylthioureathioureasEC 1.14.18.1 (tyrosinase) inhibitor2001200123.0low000100
curcuminaromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol
anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
2013201311.0low000010
sodium dodecyl sulfateorganic sodium saltdetergent;
protein denaturant
1997201617.3low003640
galactomannanoligosaccharide2007201910.3low000120
sulfosuccinimidyl 6-(biotinamido)hexanoate1998199826.0low001000
amphotericin bantibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic
antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
2006201613.0low000110
sirolimusantibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol
antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
2006200618.0low000100
tinopal cbs-x1997199727.0high001000
diamide1,1'-azobis(N,N-dimethylformamide)2008200816.0low000100
cesiumalkali metal atom2002200222.0low000100
methopreneisopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate;
isopropyl ester
juvenile hormone mimic1998199826.0low001000
cysteinecysteiniumfundamental metabolite2001200123.0low000100
1,5-bis(2-methoxy-4-nitro-5-sulfophenyl)-3-((phenylamino)carbonyl)formazan2004200420.0low000100
3,3'-dihexyl-2,2'-oxacarbocyanine1998199826.0low001000
carbocyaninescyanine dye;
organic iodide salt
fluorochrome1998200622.0low001100
tinopal1994199430.0low001000
hygromycin ahydroxycinnamic acidmetabolite2003200321.0low000100
papulacandin b1985199532.7medium012000
bis(1,3-dibutylbarbiturate)trimethine oxonol2001200123.0low000100
rylux bsu1994199430.0medium001000
fm1 43organic bromide salt;
pyridinium salt;
quaternary ammonium salt;
tertiary amine
fluorochrome201820195.5low000020
cilofunginantibiotic antifungal drug;
echinocandin
antiinfective agent1995199529.0low001000
staurosporineammonium ion derivative1997200821.5low001100
formazans2004200420.0low000100
nikkomycin1990201524.8low003010
tetramethylrhodaminexanthene dye2012201212.0low000010
aluminum oxide201520159.0low000010
acid phosphatase2005200519.0low000100
fungiqual1996199628.0high001000
tannins2004200420.0low000100
celluloseglycoside1980202217.0low030461
lucifer yelloworganic lithium saltfluorochrome2003200321.0low000100
chitosan1999201021.0low002100
hygromycin b1997201918.8low001310
clomiphene citrate2005200519.0low000100
aniline blue1991202115.0low001011
mannans1988201918.4low011420
agar201720177.0low000010
cytochalasin d2000200621.0low001100
antipain2004200420.0low000100
orabase202020204.0low000010
echinocandin b1995200026.5low002000
cyclic gmp3',5'-cyclic purine nucleotide;
guanyl ribonucleotide
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
2010201412.0low000110
trypan blue2000202113.5low001111
oosporein201520159.0low000010
bis(3',5')-cyclic diguanylic acidcyclic purine dinucleotide;
guanyl ribonucleotide
immunomodulator;
signalling molecule
2010201412.0low000110
cyanine dye 32006200618.0low000100
succinoglycan1991201816.6low002030
concanavalin a1991201220.3low001110
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Abscess, Amebic01986201428.8low021010
Acanthamoeba Keratitis01992200326.7low002100
Acquired Immune Deficiency Syndrome01996199827.0low002000
Acquired Immunodeficiency Syndrome01996199827.0low002000
Acute Confusional Senile Dementia02005200519.0low000100
Acute Disease01997199727.0low001000
Acute Hypercapnic Respiratory Failure01997199727.0low002000
AIDS-Related Opportunistic Infections01995200126.7low002100
Allergic Bronchopulmonary Mycosis0202120213.0low000001
Alzheimer Disease02005200519.0low000100
Amebiasis01986201428.8low021010
Aspergillosis02004201913.1low000430
Aspergillus Infection02004201913.1low000430
Benign Neoplasms0201520159.0low000010
Blastocystis hominis Infections01999199925.0low001000
Bordetella Infections02000200024.0low001000
Brachial Paresis0201620168.0low000010
Brain Inflammation02014201410.0low000010
Campylobacter Infection0201720177.0low000010
Cancer of Mouth0201620168.0low000010
Candida Infection02000201415.9low101520
Candidemia0202120213.0low000001
Candidiasis02000201415.9low101520
Candidiasis, Genital0202120213.0low000001
Candidiasis, Oral01987200926.0low010100
Candidiasis, Vulvovaginal0202120213.0low000001
Carcinoma, Epidermoid0201620168.0low000010
Carcinoma, Squamous Cell0201620168.0low000010
Central Nervous System Cysticercosis0201620168.0low000010
Cirrhosis, Liver0202120213.0low000001
Coccidioides immitis Infection02001200720.0low100200
Coccidioidomycosis02001200720.0low100200
Corneal Ulcer02013201311.0low000010
Dental Plaque02014201410.0low000010
Dermatomycoses01993202015.5low001120
Dermatophytoses0201620234.5low000011
Diarrhea01996201817.0low001010
Diathesis02007200717.0low000100
Dirofilariasis01994199430.0low001000
Disease Models, Animal02013201410.5low000020
Disseminated Fusariosis02013201311.0low000010
Encephalitis02014201410.0low000010
Encephalitozoonosis02001201516.0low000110
Eosinophilia, Pulmonary01997199727.0low001000
Eye Diseases01985198738.0low020000
Eye Disorders01985198738.0low020000
Eye Infections, Fungal02003202210.0low000212
Eye Infections, Parasitic02006200618.0low000100
Fish Diseases0201920195.0low000010
Foot Dermatoses02003200321.0low000100
Fungal Diseases01985200633.0low030100
Fungal Lung Diseases02007201712.0low000110
Fungemia02002200520.5low100200
Fusariosis02013201311.0low000010
Hemiplegia0201620168.0low000010
Hemiplegia, Crossed0201620168.0low000010
Herpes Simplex Keratitis02003200321.0low000100
Infections, Microspora01995201917.0low003130
Infections, Respiratory02001200123.0low100100
Inflammation02007200717.0low000100
Innate Inflammatory Response02007200717.0low000100
Keratitis01985202213.0low020215
Keratitis, Acanthamoeba01992200326.7low002100
Keratitis, Herpetic02003200321.0low000100
Keratitis, Ulcerative02013201311.0low000010
Kerion Celsi01996202314.5low001001
Liver Cirrhosis0202120213.0low000001
Lung Diseases, Parasitic01994199430.0low001000
Moniliasis, Oral01987200926.0low010100
Mouth Neoplasms0201620168.0low000010
Mycoses01985200633.0low030100
Nail Fungus02003201813.5low000110
Neoplasms0201520159.0low000010
Neurocysticercosis0201620168.0low000010
Onychomycosis02003201813.5low000110
Opportunistic Infections02010201014.0low000100
Orbital Diseases01987198737.0low010000
P carinii Pneumonia01991201224.1low006110
Pneumonia, Pneumocystis01991201224.1low006110
Pulmonary Eosinophilia01997199727.0low001000
Respiratory Insufficiency01997199727.0low002000
Respiratory Tract Infections02001200123.0low100100
Sensitivity and Specificity01993202117.9medium2051123
Sporothrix brasiliensis Infection0202120213.0low000001
Sporotrichosis0202120213.0low000001
Stomatitis, Denture02009200915.0low000100
Swine Diseases02000200024.0low001000
Tinea0201620234.5low000011
Tinea Capitis01996202314.5low001001

Safety/Toxicity (1)

ArticleYear
Effect of temperature modulation and bvg mutation of Bordetella bronchiseptica on adhesion, intracellular survival and cytotoxicity for swine alveolar macrophages.
Veterinary microbiology, , Apr-04, Volume: 73, Issue:1
2000

Pharmacokinetics (1)

ArticleYear
Quantification of cell volume changes upon hyperosmotic stress in Saccharomyces cerevisiae.
Integrative biology : quantitative biosciences from nano to macro, , Volume: 3, Issue:11
2011

Dosage (2)

ArticleYear
Highly Dynamic and Specific Phosphatidylinositol 4,5-Bisphosphate, Septin, and Cell Wall Integrity Pathway Responses Correlate with Caspofungin Activity against Candida albicans.
Antimicrobial agents and chemotherapy, , Volume: 60, Issue:6
2016
Comparative pathogenesis of Helicoverpa zea S nucleopolyhedrovirus in noctuid larvae.
The Journal of general virology, , Volume: 82, Issue:Pt 7
2001