Page last updated: 2024-12-07

selenonorcholesterol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Selenonorcholesterol is a synthetic steroidal analog of cholesterol that contains selenium in place of sulfur. It is synthesized through a multi-step process involving the introduction of selenium into the steroidal scaffold. Selenonorcholesterol has been shown to exhibit a range of biological effects, including inhibition of cholesterol biosynthesis, antioxidant activity, and anti-inflammatory properties. Its ability to inhibit cholesterol biosynthesis makes it a potential therapeutic agent for hypercholesterolemia and atherosclerosis. Selenonorcholesterol is also being investigated for its potential to protect against oxidative stress and inflammation in various tissues. The unique chemical structure and biological activities of selenonorcholesterol have made it a subject of ongoing research, with the aim of understanding its full therapeutic potential and developing novel drugs based on its structure.'

selenonorcholesterol: adrenal radioisotope scanning agents [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID122051
MeSH IDM0066925

Synonyms (24)

Synonym
scintadren
(75)selenonorcholesterol
6-methyl-(75)selenomethyl-19-norcholest-5(10)-en-3beta-ol
19-norcholest-5(10)-en-3-ol, 6-((methylseleno-(75)se)methyl) (3beta,6beta)
xwr21tj99h ,
unii-xwr21tj99h
63795-61-9
selenonorcholesterol
j40.704f ,
19-norcholest-5(10)-en-3-ol, 6-((methylseleno-75se)methyl)-, (3.beta.,6.beta.)-
72521-77-8
6.beta.-(methyl(75se)selenomethyl)-19-norcholest-5(10)-en-3.beta.-ol
6-methyl-(75)selenomethyl-19-norcholest-5(10)-en-3.beta.-ol
scintadren se-75
selenonorcholesterol (75 se) [who-dd]
selenonorcholesterol (75 se)
selenium se-75 norcholesterol
selenium (75se) norcholesterol
(3.beta.,6.beta.)-6-((methyl(75se)selanyl)methyl)-19-norcholest-5(10)-en-3-ol
DB13622
DTXSID30980361
6-{[methyl(~75~se)selanyl]methyl}-19-norcholest-5(10)-en-3-ol
Q27294031
(3s,6r,8s,9s,13r,14s,17r)-13-methyl-6-(methyl(75se)selanylmethyl)-17-[(2r)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-ol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-199015 (68.18)18.7374
1990's4 (18.18)18.2507
2000's3 (13.64)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.84 (24.57)
Research Supply Index3.30 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.00%)5.53%
Reviews4 (16.00%)6.00%
Case Studies6 (24.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (56.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]