Proteins > DNA gyrase subunit A

Page last updated: 2024-08-07 15:50:56

DNA gyrase subunit A

A DNA gyrase subunit A that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0AES4]

Synonyms

EC 5.6.2.2

Research

Bioassay Publications (37)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (24.32)	29.6817
2010's	17 (45.95)	24.3611
2020's	11 (29.73)	2.80

Compounds (18)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
ciprofloxacin	Escherichia coli K-12	IC50	5.5934	26	26
enoxacin	Escherichia coli K-12	IC50	14.0000	1	1
isoniazid	Escherichia coli K-12	IC50	1,000.0000	1	1
nalidixic acid	Escherichia coli K-12	IC50	157.5000	2	2
norfloxacin	Escherichia coli K-12	IC50	9.6000	2	2
ofloxacin	Escherichia coli K-12	IC50	1.5000	1	1
gatifloxacin	Escherichia coli K-12	IC50	0.5000	2	2
triclosan	Escherichia coli K-12	IC50	1,000.0000	1	1
4-cumylphenol	Escherichia coli K-12	IC50	390.0000	1	1
4-phenoxyphenol	Escherichia coli K-12	IC50	530.0000	1	1
bis(4-oxyphenyl)sulfide	Escherichia coli K-12	IC50	950.0000	1	1
moxifloxacin	Escherichia coli K-12	IC50	1.4000	2	2
linezolid	Escherichia coli K-12	IC50	32.0000	1	1
gemifloxacin	Escherichia coli K-12	IC50	0.5000	1	1
pd 0305970	Escherichia coli K-12	IC50	0.2000	2	2
gsk299423	Escherichia coli K-12	IC50	0.1000	1	1
novobiocin	Escherichia coli K-12	IC50	0.1441	10	10
novobiocin	Escherichia coli K-12	Ki	0.0447	1	3

Drugs with Other Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
ciprofloxacin	Escherichia coli K-12	Activity	10.7200	4	4
ciprofloxacin	Escherichia coli K-12	EC	1.2000	1	1
ofloxacin	Escherichia coli K-12	CC25	0.2000	1	1
moxifloxacin	Escherichia coli K-12	CC25	0.5000	1	1
novobiocin	Escherichia coli K-12	Activity	3.1000	1	1
clorobiocin	Escherichia coli K-12	Activity	1.6000	1	1

chemdatabank.com