| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
acetone
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H). | 3.07 | 1 | 0 | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent |
naphthalene
[no description available] | 2.05 | 1 | 0 | naphthalenes;
ortho-fused bicyclic arene | apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component |
krypton
Krypton: A noble gas that is found in the atmosphere. It has the atomic symbol Kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs. | 2.03 | 1 | 0 | monoatomic krypton;
noble gas atom;
p-block element atom | |
tyrosine
Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring. | 2.58 | 2 | 0 | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine | EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical |
ethylene
Plastipore: high density polyethylene sponge biocompatible material; used as posts in dental bridges | 2.36 | 2 | 0 | alkene;
gas molecular entity | plant hormone;
refrigerant |
acetylene
[no description available] | 6.96 | 1 | 0 | alkyne;
gas molecular entity;
terminal acetylenic compound | |
vinyl chloride
Vinyl Chloride: A gas that has been used as an aerosol propellant and is the starting material for polyvinyl resins. Toxicity studies have shown various adverse effects, particularly the occurrence of liver neoplasms.. chloroethene : A monohaloethene that is ethene in which one of the hydrogens has been replaced by a chloro group. | 4.5 | 7 | 0 | chloroethenes;
gas molecular entity;
monohaloethene | carcinogenic agent |
ethylene oxide
Ethylene Oxide: A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794). oxirane : A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. | 7.03 | 1 | 0 | gas molecular entity;
oxacycle;
saturated organic heteromonocyclic parent | allergen;
mouse metabolite;
mutagen |
1,1-difluoroethane
[no description available] | 7.03 | 1 | 0 | | |
1,1-difluoroethylene
1,1-difluoroethylene: structure | 3.48 | 2 | 0 | olefinic compound;
organofluorine compound | |
quinic acid
(-)-quinic acid : The (-)-enantiomer of quinic acid. | 2.01 | 1 | 0 | | |
chlorotrifluoroethylene
[no description available] | 3.07 | 1 | 0 | | |
1,3-butadiene
buta-1,3-diene : A butadiene with unsaturation at positions 1 and 3. | 7.03 | 1 | 0 | butadiene | carcinogenic agent;
mutagen |
propylene
propylene: structure | 1.99 | 1 | 0 | alkene;
gas molecular entity | refrigerant;
xenobiotic |
tetrafluoroethylene
tetrafluoroethylene: RN given refers to parent cpd; structure | 3.48 | 2 | 0 | fluorocarbon | |
hexafluoropropene
[no description available] | 3.07 | 1 | 0 | | |
pregnenolone
[no description available] | 2.01 | 1 | 0 | 20-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid | human metabolite;
mouse metabolite |
vinyl bromide
vinyl bromide: structure | 7.73 | 3 | 0 | bromoalkene;
monohaloethene | |
hexafluoroacetone
hexafluoroacetone: structure; RN given refers to parent cpd. hexafluoroacetone : A ketone that is acetone in which all the methyl hydrogens are replaced by fluoro groups. | 3.07 | 1 | 0 | ketone;
perfluorinated compound | NMR chemical shift reference compound |
thorium dioxide
Thorium Dioxide: Thorium oxide (ThO2). A radiographic contrast agent that was used in the early 1930s through about 1954. High rates of mortality have been linked to its use and it has been shown to cause liver cancer. | 2 | 1 | 0 | thorium molecular entity | |
hydrofluoric acid
Hydrofluoric Acid: Hydrofluoric acid. A solution of hydrogen fluoride in water. It is a colorless fuming liquid which can cause painful burns.. hydrogen fluoride : A diatomic molecule containing covalently bonded hydrogen and fluorine atoms.. organofluorine compound : An organofluorine compound is a compound containing at least one carbon-fluorine bond. | 2.06 | 1 | 0 | hydrogen halide;
mononuclear parent hydride | NMR chemical shift reference compound |
bisphenol a-glycidyl methacrylate
Bisphenol A-Glycidyl Methacrylate: The reaction product of bisphenol A and glycidyl methacrylate that undergoes polymerization when exposed to ultraviolet light or mixed with a catalyst. It is used as a bond implant material and as the resin component of dental sealants and composite restorative materials. | 1.96 | 1 | 0 | diarylmethane | |
carbonates
Carbonates: Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed). carbonates : Organooxygen compounds that are salts or esters of carbonic acid, H2CO3. | 2.41 | 1 | 0 | carbon oxoanion | |
silver nitrate
Silver Nitrate: A silver salt with powerful germicidal activity. It has been used topically to prevent OPHTHALMIA NEONATORUM. | 1.94 | 1 | 0 | inorganic nitrate salt;
silver salt | astringent |
fluorine
Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries. | 7.41 | 2 | 0 | diatomic fluorine;
gas molecular entity | NMR chemical shift reference compound |
fluoroboric acid
[no description available] | 2.25 | 1 | 0 | boron fluoride | |
fluorides
[no description available] | 2.64 | 3 | 0 | halide anion;
monoatomic fluorine | |
alkenes
[no description available] | 2.38 | 2 | 0 | | |
finasteride
Finasteride: An orally active 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE inhibitor. It is used as a surgical alternative for treatment of benign PROSTATIC HYPERPLASIA.. finasteride : An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia. | 1.99 | 1 | 0 | 3-oxo steroid;
aza-steroid;
delta-lactam | androgen antagonist;
antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor |
perfluoroisobutylene
[no description available] | 3.07 | 1 | 0 | | |
n(2),3-ethenoguanine
N(2),3-ethenoguanine: formed from 2-halooxiranes. N(2),3-ethenoguanine : A nucleobase analogue obtained by addition of an etheno group across positions N2 and 3 of guanine. | 2 | 1 | 0 | imidazopurine;
nucleobase analogue | |
lithium
Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER. | 2.41 | 1 | 0 | alkali metal atom | |
calcitriol
dihydroxy-vitamin D3: as a major in vitro metabolite of 1alpha,25-dihydroxyvitamin D3, produced in primary cultures of neonatal human keratinocytes | 2.03 | 1 | 0 | D3 vitamins;
hydroxycalciol;
triol | antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical |
silicon
Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086]. | 2.1 | 1 | 0 | carbon group element atom;
metalloid atom;
nonmetal atom | |
1,25-dihydroxy-19-norvitamin d3
1,25-dihydroxy-19-norvitamin D3: RN refers to (1alpha,3beta,7E)-isomer; structure given in first source | 2.03 | 1 | 0 | | |
guanine
[no description available] | 2 | 1 | 0 | 2-aminopurines;
oxopurine;
purine nucleobase | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |